{"title":"ACOUSTIC RHINOMETRY STUDY IN PATIENTS WITH ALLERGIC RHINITIS.","authors":"Atanas Vlaykov","doi":"10.20471/acc.2024.63.03-04.42","DOIUrl":"https://doi.org/10.20471/acc.2024.63.03-04.42","url":null,"abstract":"<p><p>Acoustic rhinometry is a non-invasive technique that requires minimal cooperation from patients compared to other diagnostic methods. This technique can be used even in children under 3 years of age, which makes it widely applicable in the practice of rhinologists. The aim of this research was to study nasal patency and nasal volume in patients with persistent allergic rhinitis (PAR) and intermittent allergic rhinitis (IAR) using acoustic rhinometry and to compare the degree of swelling of the nasal mucosa in patients with different forms of the disease. The study was conducted on the territory of the University Hospital \"Prof. Dr. St. Kirkovich\" (Stara Zagora, Bulgaria), where 139 participants (111 with allergic rhinosinusitis [AR] and 28 controls), aged 19 to 84 years, were examined. To compare the results, an acoustic rhinometry study was performed on the participants and the control group. The main indicators considered were the volume of the nasal cavity, the minimum cross-section area of the left and right halves, as well as the distance from the nasal entrance where it is located. To check the reactivity of the nasal mucosa, the same test was repeated after using a nasal decongestant. Increased nasal mucosal swelling in patients with IAR than those with PAR has been found. More manifested nasal congestion is observed in patients with IAR, probably because pollen has a stronger immunological stimulus and causes more manifested expression of symptoms than allergens provoking year-round forms of AR. A severely reduced reactive response to nasal decongestants has been demonstrated in participants with persistent AR.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"801-807"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS (AGEP) CAUSED BY ANTIBIOTIC POLYTHERAPY: A CASE REPORT.","authors":"Siniša Jolić, Zdenka Šitum Čeprnja, Toni Čeprnja, Ognjen Jolić, Mirna Šitum","doi":"10.20471/acc.2024.63.03-04.48","DOIUrl":"https://doi.org/10.20471/acc.2024.63.03-04.48","url":null,"abstract":"<p><p>Acute generalized exanthematous pustulosis (AGEP) is a rare disease, usually associated with drug intake or infections. It is characterized by generalized acute pustules and non-follicular exanthema together with systemic symptoms. Histologically, it is characterized by a subcorneal intraepidermal spongiform pustule, papillary edema and dermal vasodilatation surrounded by a polymorphous infiltrate of neutrophils, eosinophils and mononuclear cells. The aim of this article is to present current knowledge regarding the etiology and treatment, as well as the clinical and histologic features of AGEP. We present a case of a 50-year-old male patient who was prescribed several antibiotics and developed a drug-related cutaneous adverse effect. Treatment involved rapid identification of the causative agent and its discontinuation together with supportive measures, with resolution of symptoms within two weeks. Early diagnosis and timely treatment result in a favorable outcome and prevent systemic complications.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"834-838"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490489/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Uğur Bozlar, Hatice Merve Sahin, Cantürk Tasci, Eda Karaismailoglu, Sümeyra Altekin, Kenan Saglam, Mustafa Tasar
{"title":"COMPARISON OF CT REPORTING SYSTEMS IN PATIENTS UNDERGOING THORAX COMPUTED TOMOGRAPHY FOR COVID-19 PNEUMONIA.","authors":"Uğur Bozlar, Hatice Merve Sahin, Cantürk Tasci, Eda Karaismailoglu, Sümeyra Altekin, Kenan Saglam, Mustafa Tasar","doi":"10.20471/acc.2024.63.03-04.11","DOIUrl":"https://doi.org/10.20471/acc.2024.63.03-04.11","url":null,"abstract":"<p><p>We aimed to compare three commonly used computed tomography (CT) reporting systems for COVID-19, i.e., Radiological Society of North America (RSNA) Consensus, British Society of Thoracic Imaging (BSTI) Guideline, and Dutch Radiological Society Categorical CT Assesment Scheme: COVID-19 Reporting and Data System (CO-RADS). Three thousand thoracic CT scans taken consecutively because of COVID-19 suspicion, diagnosis or follow-up after admission to our hospital between March 2020 and May 2020 were studied. All CT examinations were assigned to the appropriate groups of the aferomentioned CT reporting systems and these systems were compared with each other. Thorax CT imaging did not reveal any findings indicative of infection (RSNA: 40.7%, BTSI: nonapplicable, and CO-RADS: 40.1%) in the vast majority of polymerase chain reaction (PCR) (+) cases in all three reporting systems. The highest number of cases was included in the groups classified as typical/classic/CO-RADS 5 findings in all three reporting systems (RSNA: 213, BSTI: 212, and CO-RADS:101) in COVID-19 diagnosed cases with lung findings. There was no significant difference between PCR (+) and (-) cases with probable COVID-19 infection according to BSTI reporting system and CO-RADS 4 cases (30/23, p=0.381 and 22/19, p=0.245, respectively). In addition, typical thoracic CT findings were observed in RSNA: 70, BSTI: 71, CO-RADS: 71 individuals in all three classifications, but the PCR result was detected negative. When the three reporting systems were compared, we concluded that they did not show distinct advantage to each other and all three ensured that patients were properly classified with similar accuracy.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"533-541"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CLINICAL EVALUATION, DIAGNOSIS AND TREATMENT OF PHEOCHROMOCYTOMA.","authors":"Romana Marušić, Tajana Turk, Tatjana Bačun","doi":"10.20471/acc.2024.63.03-04.07","DOIUrl":"https://doi.org/10.20471/acc.2024.63.03-04.07","url":null,"abstract":"<p><p>Pheochromocytomas are rare neuroendocrine tumors that originate in chromaffin cells of the adrenal medulla and excessively secrete catecholamines, which leads to a multitude of different symptoms. The most common symptoms include headaches, palpitations, and sweating. Because of a diverse clinical presentation, pheochromocytomas pose a major diagnostic challenge and often go unidentified. These tumors can occur sporadically or as a part of hereditary syndromes. The diagnosis is confirmed by measuring plasma and 24-hour urinary metanephrine and normetanephrine. Computed tomography, magnetic resonance imaging, and functional morphological examinations are used for tumor localization. The treatment is operative and requires special preoperative patient preparation to prevent hypertensive crisis and arrhythmias. Due to the possibility of recurrence, the patient needs to be monitored. Pheochromocytoma has a high fatality rate if not recognized on time due to the effect of catecholamines on the cardiovascular system.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"501-512"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Petra Kovačević, Ivana Gusar, Marija Ljubičić, Nika Samardžić, Doroteja Caktaš, Matej Lovrić, Klara Lauš, Petra Pantalon, Juraj Pantalon, Ana-Marija Gusar, Katarina Vukojević
{"title":"KNOWLEDGE, ATTITUDES AND BEHAVIOR OF MEDICAL STUDENTS REGARDING APPROPRIATE COVID-19 PROTECTION: A CROSS-SECTIONAL STUDY OF CROATIAN AND BOSNIAN MEDICAL STUDENTS.","authors":"Petra Kovačević, Ivana Gusar, Marija Ljubičić, Nika Samardžić, Doroteja Caktaš, Matej Lovrić, Klara Lauš, Petra Pantalon, Juraj Pantalon, Ana-Marija Gusar, Katarina Vukojević","doi":"10.20471/acc.2024.63.03-04.32","DOIUrl":"https://doi.org/10.20471/acc.2024.63.03-04.32","url":null,"abstract":"<p><p>The aim of this cross-sectional study was to determine the knowledge, attitudes and behavior of medical students in relation to COVID-19 according to different medical schools and duration of studies. A validated questionnaire was administered to 192 medical students at two universities in Croatia and one from Bosnia and Herzegovina. Fisher-Freeman-Halton and Kruskal-Wallis tests were used to examine differences among study groups. The association of variables was tested with a linear regression model. A negative correlation was found between adherence to measures and attitudes (ß=-0.36; p<0.001). Studying at the University of Zagreb was positively associated with students' knowledge about COVID-19 (ß=0.24; p=0.033) but negatively with students' attitudes (ß= 0.26; p=0.013). Compared to the last study year students, second-year students had lower knowledge (ß=-0.28; p=0.040) and statistically nonsignificant negative attitudes (ß=-0.24; p=0.055). Fifth-year students had more negative attitudes (ß=-0.24; p=0.008) compared to sixth-year students. The association between knowledge and attitudes was weak and statistically borderline nonsignificant (ß=0.14; p=0.056). The lack of association between knowledge and attitudes requires additional research to identify the potential factors that favor the formation of attitudes toward appropriate protection against COVID-19.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"710-723"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana-Meyra Potkonjak, Ivana Terzić, Mario Lovrić, Vesna Gall, Hrvojka Soljačić Vraneš, Danko Milošević, Neven Tučkar, Goran Vujić, Vesna Košec, Ana Budimir, Boris Filipović-Grčić
{"title":"ETIOLOGY OF URINARY TRACT INFECTIONS IN NEONATES AND BACTERIAL RESISTANCE IN CROATIA.","authors":"Ana-Meyra Potkonjak, Ivana Terzić, Mario Lovrić, Vesna Gall, Hrvojka Soljačić Vraneš, Danko Milošević, Neven Tučkar, Goran Vujić, Vesna Košec, Ana Budimir, Boris Filipović-Grčić","doi":"10.20471/acc.2024.63.03-04.26","DOIUrl":"https://doi.org/10.20471/acc.2024.63.03-04.26","url":null,"abstract":"<p><p>Urinary tract infection (UTI) occurs in approximately 15% of full-term neonates and 8% of those born before 37 weeks of gestation. Severe UTI can lead to sepsis or long-term complications such as renal scarring and hypertension. Given the rising concern of bacterial resistance to antibiotics, this research aimed to examine the epidemiology of neonatal UTI, most common antibiotic prescription patterns, as well as resistance of the causative agents in Croatia. This retrospective multicenter analysis was focused on neonates born in 2005 and 2015. Of the 103 bacterial UTI cases, 78.6% affected term neonates. Male neonates constituted 62.1% of the study population. Eutrophic neonates accounted for 87.4%, and hospital-acquired infections were prevalent in 47.6% of cases. The main causative pathogens were <i>Escherichia coli</i> (60.2%) and <i>Klebsiella pneumoniae</i> (28.2%). Most commonly prescribed empirical antibiotics included ceftriaxone (31.1%) and the ampicillin-gentamicin combination (10.7%). In 2005, 72.7% of isolates were sensitive to empirical therapy. In 2015, sensitivity to empirical antibiotic therapy was observed in 75.6% of cases. In this study, <i>Escherichia coli</i> frequently exhibited antibiotic resistance to ampicillin, amoxicillin, trimethoprim-sulfamethoxazole, and gentamicin. For UTIs attributed to <i>Klebsiella pneumoniae</i>, the prevailing bacterial resistance was observed against gentamicin, ceftibuten, ampicillin, cefazolin, and piperacillin. The predominance of <i>Escherichia coli</i> as the most common pathogen causing UTI was consistent with global trends. Founded on continuous differences in bacterial resistance, this study can serve as a basis for comprehending local resistance patterns of pathogens causing neonatal UTI, highlighting the need of additional prospective research.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"662-669"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucija Pavljak, Krešimir Bulić, Maksimilian Mrak, Anko Antabak
{"title":"SKIN SURFACE TEMPERATURE CHANGES BEFORE AND AFTER MEDIAN NERVE DECOMPRESSION IN CARPAL TUNNEL SYNDROME.","authors":"Lucija Pavljak, Krešimir Bulić, Maksimilian Mrak, Anko Antabak","doi":"10.20471/acc.2024.63.03-04.41","DOIUrl":"https://doi.org/10.20471/acc.2024.63.03-04.41","url":null,"abstract":"<p><p>Carpal tunnel syndrome is the most common upper extremity compression neuropathy caused by compression of the median nerve at the wrist. Along with motor and sensory fibers, sympathetic fibers also pass through the median nerve, playing an important role in the regulation of blood flow to the skin which interacts between the body interior and its environment. The aim of this study was to examine the preand postoperative correlation between skin temperature changes in the area innervated by compressed median nerve compared to the skin areas innervated by radial and ulnar nerve and median nerve of the unaffected hand. The study included 16 patients with carpal tunnel syndrome with an indication for open carpal tunnel decompression. Skin temperature was measured preoperatively, at 2-week, 2and 6-month follow-ups on the areas innervated by median, ulnar and radial nerve of the affected hand and median nerve of the non-affected hand. On the affected hand, median nerve innervated skin temperature showed maximum increase at 2-month follow-up before decreasing to a level higher than preoperatively. Radial nerve innervated skin temperature was lower than the preoperative value at 2-week follow-up, increasing to higher levels afterwards. Ulnar nerve temperature followed the curve of the median nerve innervated skin at all follow-ups. Unaffected median nerve innervated skin temperature increased at all follow-ups compared to the preoperative values. In conclusion, two or even five additional measurements should be made after at least one year. The results should be correlated with clinical and electromyoneurography recovery.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"795-800"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lada Lijović, Josip Jaman, Yannick Mudrovčić, Dominik Ivanković, Katarina Jelić, Lana Videc Penavić, Tomislav Radočaj, Hrvoje Silovski
{"title":"CHANGES IN PRE-AND POST-INTERVENTION HAND HYGIENE COMPLIANCE IN ICU ON WHO HANDWASHING POSTERS.","authors":"Lada Lijović, Josip Jaman, Yannick Mudrovčić, Dominik Ivanković, Katarina Jelić, Lana Videc Penavić, Tomislav Radočaj, Hrvoje Silovski","doi":"10.20471/acc.2024.63.03-04.17","DOIUrl":"https://doi.org/10.20471/acc.2024.63.03-04.17","url":null,"abstract":"<p><p>Healthcare-associated infections (HAI) cause more deaths in the European Union than all other infectious diseases. Hand hygiene (HH) has been considered the most important means of preventing HAIs but HH compliance is generally less than 50%. One of the five steps that the World Health Organization (WHO) guidelines identify to be specifically implemented are poster reminders. The aim of this study was to evaluate compliance with HH by healthcare workers before and after an intervention on standardized WHO HH poster reminders. An observational one-month study was conducted in a university hospital center surgical intensive care unit. HH compliance was measured through direct observation using WHO observation tool. Intervention was done on day 15 by replacement of standard WHO posters with posters containing a message aimed to call for personal responsibility in patient outcome. A total of 1113 HH opportunities were observed. Overall, HH was performed in 15.4% of cases pre-intervention and 28.3% of cases post-intervention (p<0.001). The preferred method of HH was soap and water. Healthcare workers mostly chose to perform HH after exposure to body fluids, where compliance was 35.1% pre-intervention and 58.7% post-intervention. Gloves were used in 98% of cases of clean/aseptic procedures where HH was not performed. In conclusion, using standard posters to convey additional messages of awareness of consequences and personal responsibility may improve HH and should be considered in multimodal approaches to improve HH compliance.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"588-594"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ESOPHAGEAL DIAMETER ON HIGH-RESOLUTION COMPUTED TOMOGRAPHY - A POTENTIAL USEFUL MARKER FOR INTERSTITIAL LUNG DISEASE SEVERITY IN PATIENTS WITH SYSTEMIC SCLEROSIS.","authors":"Anja Ljilja Posavec, Lea Šalamon, Renata Huzjan Korunić, Nevenka Piskač Živković, Joško Mitrović","doi":"10.20471/acc.2024.63.03-04.30","DOIUrl":"https://doi.org/10.20471/acc.2024.63.03-04.30","url":null,"abstract":"<p><p>Patients with systemic sclerosis (SSc) are at an increased risk of developing interstitial lung disease (ILD) and esophageal dysfunction, with frequently present esophageal dilatation. Our study aimed to investigate the relationship between esophageal diameter (ED) analyzed on high-resolution computed tomography (HRCT) with lung function tests and ILD evaluated with Warrick score. Thirty-nine patients with SSc were enrolled in this study. ED and Warrick score were evaluated by HRCT. The relationships between Warrick score, lung function, and ED were analyzed. Multivariate regression analysis was used to determine the effect of individual predictors on SSc-ILD. ILD was present in 25 (64%) patients. ED >10 mm in one or more of the measured locations on HRCT was present in 25 (64%) patients and 19 (76%) of these patients had concurrent ILD. Subjects with esophageal dilatation had a higher Warrick score and lower lung function tests. The measurement of ED was able to predict the presence of ILD in 69% of patients. Results suggest that evaluation of ED during regular HRCT follow-up could be useful in patients with SSc due to the association of esophageal dilatation with worse lung function tests and a more severe form of ILD.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"693-700"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivan Bohaček, Mihovil Plečko, Hrvoje Lindi, Drago Plečko, Mirna Vranić Ladavac, Jasmina Kučinar, Tomislav Čengić, Aleksandar Stojanović, Domagoj Delimar
{"title":"RAPID ANTIGEN TESTING FOR COVID-19 SHOULD BE AVOIDED AS SCREENING TEST AT LARGE SPORTING EVENTS WITH CLOSE PHYSICAL CONTACT BETWEEN COMPETITORS.","authors":"Ivan Bohaček, Mihovil Plečko, Hrvoje Lindi, Drago Plečko, Mirna Vranić Ladavac, Jasmina Kučinar, Tomislav Čengić, Aleksandar Stojanović, Domagoj Delimar","doi":"10.20471/acc.2024.63.03-04.14","DOIUrl":"https://doi.org/10.20471/acc.2024.63.03-04.14","url":null,"abstract":"<p><p>Large sporting events during the pandemic are organized as 'COVID-19 free zones', function under quarantine measures, and are regularly testing all participants. Recently, point-of-care tests (POCT) for rapid detection of COVID-19 antigen were presented as a cheaper, faster, and easier-to-perform option than reverse transcription polymerase chain reaction (RT-PCR) testing. However, no study confirmed the efficacy of POCT used at a large sporting event that includes close physical contact, such as judo. An observational study was conducted that included 670 participants from 36 countries attending two consecutive judo competitions. In total, 839 RT-PCR tests and 839 POCT tests for COVID-19 were performed. There were 508 participants tested at one time point when entering the venue, while 162 were tested at two time points in order to participate in both competitions. Seven subjects had positive RT-PCR results, while 4 had positive POCT results, meaning the prevalence of COVID-19 at the competitions was 1.04% according to the RT-PCR results. The main finding of this study was that POCT testing proved to be an effective method in detecting true-negative results. However, due to sensitivity that is insufficient to detect all true-positive cases, POCT should always be used in combination with RT-PCR at large sporting events with close physical contact between competitors in order to avoid COVID-19 outbreak.</p>","PeriodicalId":7072,"journal":{"name":"Acta clinica Croatica","volume":"63 3-4","pages":"560-567"},"PeriodicalIF":0.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}