Acta Medica PhilippinaPub Date : 2024-09-30eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i17.7501
Kimberly Anne G Ednalino, Claudine Yap-Silva
{"title":"Alopecia Induced by Fluoroscopy-guided Embolization: A Case Report.","authors":"Kimberly Anne G Ednalino, Claudine Yap-Silva","doi":"10.47895/amp.v58i17.7501","DOIUrl":"10.47895/amp.v58i17.7501","url":null,"abstract":"<p><p>Alopecia resulting from radiation exposure occurs 2-8 weeks after exposure. It can be temporary or permanent depending on the dose of exposure. Alopecia following fluoroscopy-guided procedures are increasing in frequency. We report the case of a 22-year-old female who underwent fluoroscopically-guided embolization of an arteriovenous malformation. Twelve days after embolization, significant hair shedding was noted, resulting in a large rectangular hairless patch with no erythema or pain on the irradiated site. Hair pull test was positive and the hair mount showed dystrophic anagen hairs. Hair tug test was negative. Trichoscopy showed yellow dots, black dots, vellus hairs, and flame hairs. Histopathologic examination showed an increase in catagen and telogen hairs. On review of the procedure, she received a total peak skin dose of 4.67 Gray from the procedure. The diagnosis of radiation-induced alopecia was made and topical minoxidil was started, resulting in complete hair growth after six months. Patients undergoing fluoroscopy-guided procedures should have adequate follow-up weeks to months post-procedure to monitor for skin and hair reactions. Physicians should also consider delayed radiation reactions in patients with a history of radiation exposure. Safety protocols must be in place, and measures should be done to minimize the dose delivered.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 17","pages":"106-109"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-09-30eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i17.9010
Ysabel Regina H Ortiz, Maria Christina Filomena R Batac
{"title":"Botryomycosis Secondary to <i>Staphylococcus simulans</i> Masquerading as Mycetoma in a 46-year-old Filipino Female.","authors":"Ysabel Regina H Ortiz, Maria Christina Filomena R Batac","doi":"10.47895/amp.v58i17.9010","DOIUrl":"10.47895/amp.v58i17.9010","url":null,"abstract":"<p><p>Botryomycosis is a rare pyogenic disease that presents with chronic suppurative and granulomatous skin lesions, commonly caused by <i>Staphylococcus aureus</i>. We report a case of botryomycosis presenting similarly to mycetoma, secondary to the emerging cutaneous pathogen <i>Staphylococcus simulans.</i> A 46-year-old female who previously worked in a wet market presented with a 13-year history of suppurative papules on a gradually enlarging right foot, and pain on ambulation. She had no systemic symptoms or co-morbidities, and does not recall preceding trauma. Physical examination showed brawny edema of the right foot with multiple sinus tracts draining purulent discharge. The clinical diagnosis at presentation was mycetoma. Magnetic resonance imaging showed a soft tissue mass involving the right foot and ankle with osseous destruction. Biopsy revealed suppurative granulomatous dermatitis; staining with Grocott methenamine silver did not highlight fungal elements. Potassium hydroxide mount of the purulent discharge did not show grains or hyphal elements. Tissue cultures showed growth of co-trimoxazole-susceptible <i>Staphylococcus simulans</i>. The patient was managed as a case of botryomycosis and treated with co-trimoxazole for 12 months. There was a significant decrease in right foot circumference along with scarring and resolution of associated pain. Repeat biopsy showed no evidence of infection. This is the first reported case of botryomycosis in the Philippines as well as the first report citing <i>Staphyloccocus simulans</i> as a causative agent. Botryomycosis is an important differential in patients clinically presenting as mycetoma. Animal pathogens may need to be considered as etiologic agents in at-risk patients with chronic subcutaneous infections.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 17","pages":"64-68"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-09-30eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i17.9670
Mary Antonette D Atienza, Maragaille R Capiroso, Maria Christina Filomena R Batac, Antonio C Sison
{"title":"Knowledge, Attitude, and Practice Patterns on Psychodermatology among Filipino Dermatologists: A Cross-sectional Study.","authors":"Mary Antonette D Atienza, Maragaille R Capiroso, Maria Christina Filomena R Batac, Antonio C Sison","doi":"10.47895/amp.v58i17.9670","DOIUrl":"10.47895/amp.v58i17.9670","url":null,"abstract":"<p><strong>Background: </strong>Psychodermatology is a field that focuses on the interaction of the skin and the mind. Psychodermatology patients are often challenging to manage because they often lack insight and are not amenable to psychiatric treatment or referral. Therefore, it is important that dermatologists become aware of the psychosocial impact of cutaneous disease and be knowledgeable in the fundamentals of psychodermatologic diagnosis and therapy. However, studies done in several countries report a general lack of perceived knowledge, awareness, and confidence in the management of psychodermatology disorders among dermatologists.</p><p><strong>Objective: </strong>This study aims to determine the knowledge, attitudes, and practices of Filipino dermatologists towards psychodermatology using a self-administered questionnaire.</p><p><strong>Methods: </strong>This is a mixed methods study using qualitative and quantitative measures. A self-administered questionnaire was validated and disseminated among the dermatologists in the country. Descriptive analysis was done.</p><p><strong>Results: </strong>Of the 153 participating dermatologists, majority (70.59%) reported psychodermatologic patients comprised <10% of their practice. While more than half (56.2%) have a clear understanding of psychodermatology and are comfortable (57.52%) in approaching patients with these conditions, only 58 (37.91%) participants are able to demonstrate adequate knowledge on psychodermatology. Patients with primary psychiatric disorders are less frequently encountered than dermatologic disorders with psychiatric component or secondary psychiatric disorders. Most commonly prescribed medications are anti-histamines. Other psychotropic medications are rarely or never prescribed by the participants. All participants agree that psychodermatology is important in the practice of dermatology; 127 (62.1%) have attended at least one Continuing Medical Education (CME) on psychodermatology and 114 (74.51%) expressed willingness to attend CME training in psychodermatology. One hundred nine (71.24%) participants think that the best practice approach is a multidisciplinary approach to psychodermatology. The top recommendations for better healthcare delivery in psychodermatology were better access to mental health specialists (86.27%), more training opportunities and better training during residency (75.16%), and increase collaboration with psychiatrists (71.9%). The knowledge score was found to be associated with the duration of dermatology practice and attendance in CME proceedings but was not associated with the perceived adequacy of knowledge gained during training. Longer duration of practice may be associated with the knowledge score owing to the greater exposure to cases and more access to training opportunities.</p><p><strong>Conclusions: </strong>There are many challenges to providing psychodermatologic care in the Philippines but the positive attitude towards psychoderma","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 17","pages":"50-59"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-09-30eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i17.9202
Denise Marie B David, Koreen Blossom T Chan, Carmela Augusta F Dayrit-Castro
{"title":"5% Simvastatin Ointment as Treatment for Congenital Hemidysplasia with Ichthyosiform Erythroderma and Limb Defects (CHILD) Syndrome in a 4-year-old Female: A Case Report.","authors":"Denise Marie B David, Koreen Blossom T Chan, Carmela Augusta F Dayrit-Castro","doi":"10.47895/amp.v58i17.9202","DOIUrl":"10.47895/amp.v58i17.9202","url":null,"abstract":"<p><p>A 4-year-old female with Congenital Hemidysplasia with Ichthyosiform erythroderma and Limb Defects (CHILD) syndrome, with a pathogenic variant of the NSDHL gene, c.130G>A (p.Gly44Ser), and unilateral right-sided erythematous verrucous plaques with scaling and ipsilateral limb defects, was started on 5% simvastatin ointment. It was applied twice daily for four months, with improvement already seen starting week 2. Monotherapy with 5% simvastatin ointment was able to decrease the thickness of the verrucous plaques seen in our patient, highlighting that the accumulation of toxic metabolites may play a more crucial role in its disease pathogenesis.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 17","pages":"94-99"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-09-30eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i17.9040
Marian Rosel D Villaverde, Juan Paolo David S Villena, Claudine Yap Silva
{"title":"A Peculiar Pattern: Nodular Secondary Syphilis with Granulomatous Dermatitis.","authors":"Marian Rosel D Villaverde, Juan Paolo David S Villena, Claudine Yap Silva","doi":"10.47895/amp.v58i17.9040","DOIUrl":"10.47895/amp.v58i17.9040","url":null,"abstract":"<p><p>Nodular syphilis with a granulomatous inflammatory histopathologic pattern is an uncommon cutaneous presentation of secondary syphilis which could pose a diagnostic challenge for clinicians and pathologists alike. A 33-year-old male diagnosed with HIV presented with a 5-week history of asymptomatic generalized erythematous papules and nodules with overlying scales, with involvement of the palms and soles. Histopathologic examination of a nodule from the forearm revealed non-caseating granulomas in a background of a mixed cell inflammatory infiltrate composed of lymphocytes, epithelioid and foamy histiocytes, plasma cells, neutrophils, and multinucleated giant cells. Warthin-Starry Stain revealed spirochetal organisms, while Fite-Faraco and Periodic Acid-Schiff stains were negative for acid-fast bacilli and fungal elements, respectively. Rapid plasma reagin (RPR) was reactive (1:256). Patient was given a single dose of benzathine penicillin G 2.4 million units intramuscularly, with noted complete resolution of skin lesions as well as an 8-fold decrease in RPR titers. Nodular lesions are an uncommon cutaneous manifestation of secondary syphilis, and the associated histopathologic finding of granulomatous inflammatory pattern is also unusual, posing a diagnostic challenge. With the increasing prevalence of syphilis, especially among HIV patients, dermatologists, dermatopathologists, internists, and infectious disease specialists should be aware of such presentations of syphilis.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 17","pages":"60-63"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-09-30eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i17.9703
Rowena F Genuino, Ma Christina Filomena R Batac, Alena Marie B Mariano, Ma Carla E Buenaflor, Ma Veronica Pia N Arevalo, Francis R Capule, Fernando B Garcia, Mary Ann J Ladia, Malaya P Santos, Ailyn M Yabes, Maria Stephanie Fay S Cagayan
{"title":"Understanding Perceptions and Experiences on Acceptability of Oral Ivermectin, Topical Permethrin, and their Combination in the Treatment of Adult Filipino Patients with Scabies: A Multiple Case Study.","authors":"Rowena F Genuino, Ma Christina Filomena R Batac, Alena Marie B Mariano, Ma Carla E Buenaflor, Ma Veronica Pia N Arevalo, Francis R Capule, Fernando B Garcia, Mary Ann J Ladia, Malaya P Santos, Ailyn M Yabes, Maria Stephanie Fay S Cagayan","doi":"10.47895/amp.v58i17.9703","DOIUrl":"10.47895/amp.v58i17.9703","url":null,"abstract":"<p><strong>Background and objective: </strong>Oral ivermectin, a broad-spectrum anti-parasitic drug, alone or in combination with permethrin, may be a cheaper and more convenient alternative drug to topical permethrin alone in the treatment of classic scabies. There are no previous studies on the treatment acceptability of the three interventions among individual patients with scabies in the Philippines.The purpose of this study was to understand the experiences and perceptions on treatment acceptability for oral ivermectin, topical permethrin or combination treatment among patients with scabies using the multiple-case study approach.</p><p><strong>Methods: </strong>We conducted a qualitative multiple case study among adult Filipino patients with classic scabies who were prescribed oral ivermectin, topical permethrin or its combination at a government tertiary hospital dermatology outpatient clinic from December 2022 to September 2023. Semi-structured interviews were used as the primary source of data and analyzed together with chart reviews, Dermatology Life Quality Index (DLQI) scores, and clinical images. Interviews were transcribed, coded, and triangulated with other secondary data. A three-person research team employed a reflexive and iterative process of familiarization, coding, and thematic analysis using a modified Theoretical Framework of Acceptability (TFA) to generate case descriptions, within-case analyses, and cross-case syntheses.</p><p><strong>Results: </strong>The acceptability of scabies treatments (permethrin, ivermectin, and combination therapy) was generally positive. Permethrin, used in three patient cases, was generally perceived as effective but itch relief varied. The burden of whole-body application of permethrin was context-dependent, influenced by living arrangements and family support. Perceived affordability of permethrin was linked to socioeconomic status. Ivermectin, used by one patient case, was perceived as highly effective with no side effects. Its single dose use did not interfere with patient routine. Combination therapy was also considered effective but potential antagonistic effects and the cost of adding permethrin made it less preferred. Reluctance in taking oral pills was noted. All patients valued medical advice and deferred to their physicians for treatment decisions.</p><p><strong>Conclusion and recommendations: </strong>All three treatment options were considered effective and safe. Patients generally preferred permethrin over oral ivermectin due to its topical nature and perceived lower side effects. However, affordability and logistical challenges, especially for large households and low-income families, were noted with permethrin. Oral ivermectin elicited hesitation due to its controversial role in COVID-19 and veterinary use. Concerns about added costs and potential antagonism in combination therapy were raised. Despite these considerations, patients ultimately relied on physicians for treatment de","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 17","pages":"24-41"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-09-30eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i17.7495
Amanda Christine F Esquivel, Juan Raphael M Gonzales, Geraldine T Zamora, Giselle Marie S Tioleco-Ver
{"title":"Bullous Herpes Zoster in a Lupus Nephritis Patient Treated with Rituximab: A Case Report.","authors":"Amanda Christine F Esquivel, Juan Raphael M Gonzales, Geraldine T Zamora, Giselle Marie S Tioleco-Ver","doi":"10.47895/amp.v58i17.7495","DOIUrl":"10.47895/amp.v58i17.7495","url":null,"abstract":"<p><p>Herpes zoster is a clinical syndrome associated with reactivation of varicella zoster virus (VZV), often occurring years after VZV infection, and characterized typically by painful grouped vesicles in a dermatomal distribution. Bullous herpes zoster, an atypical presentation of herpes zoster, is a relatively rare phenomenon; to the authors' knowledge, there have only been eight reports in worldwide literature. We present a case of a 59-year-old female with lupus nephritis who presented with multiple grouped vesicles evolving into large tender bullae filled with serosanguinous fluid on the lateral aspect of the right leg, and dorsal and medial aspects of the right foot, four days after the first dose of 1g of rituximab therapy. The diagnosis of bullous herpes zoster along L4-L5 dermatomes was made based on the clinical presentation and the presence of multinucleated giant cells on Tzanck smear. The giant bullae were drained and dressed, and the patient was treated with valacyclovir at the renally adjusted dose of 1g once a day for seven days and pregabalin 150 mg once daily. After seven days of antiviral treatment, there were no new bullae or vesicles, and the pain improved. Recognizing this atypical presentation of a common disease, especially in patients with an immunocompromised state, highlights the importance of prompt recognition and treatment.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 17","pages":"69-73"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-09-30eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i17.7474
Aznaida T Pandapatan, Belen L Dofitas, Mia Katrina R Gervasio, Jolene Kristine G Dumlao
{"title":"Knowledge, Attitudes, and Practices of Barangay Health Workers in Marawi City regarding Hansen's Disease.","authors":"Aznaida T Pandapatan, Belen L Dofitas, Mia Katrina R Gervasio, Jolene Kristine G Dumlao","doi":"10.47895/amp.v58i17.7474","DOIUrl":"10.47895/amp.v58i17.7474","url":null,"abstract":"<p><strong>Objective: </strong>To assess the knowledge, attitudes, and practices of Barangay Health Workers (BHWs) in Marawi City regarding Hansen's Disease (HD).</p><p><strong>Methods: </strong>A cross-sectional study was conducted among the Barangay Health Workers of Marawi City. This study was conducted in two phases. Phase 1 was questionnaire development where the knowledge, attitudes, and practices (KAP) questionnaire was formulated and administered to six Barangay Health Workers for pre-testing. Phase 2 of the study included the survey and focus group discussion (FGD). A questionnaire comprising of 27 questions was administered to BHWs to assess knowledge, attitude, and practices regarding HD.</p><p><strong>Results: </strong>A total of 49 BHWs underwent the Phase 2 survey and six BHWs joined the FGD. The mean age of all the survey participants was 34.9 ± 19.3 years. Among the 49 participants, 40 (81.6%) were females. The knowledge of BHWs was found to be adequate only in six (12%) BHWs. Positive attitude was observed in 12 (24.5%) and adequate practices regarding HD were observed in 33 (67.3%) BHWs. First-hand experience of diagnosing HD patients was significantly associated with adequate knowledge (p < 0.001) and positive attitude of BHWs (p < 0.001). There was a significant association between > 5 years of experience as BHWs (p = 0.027) and first-hand experience in diagnosing leprosy (p = 0.005) with adequate practices of BHWs regarding HD. In the FGD, BHWs expressed their lack of training which highlighted the need for refresher courses on HD.</p><p><strong>Conclusions: </strong>Knowledge about HD is low among Marawi BHWs due to their inadequate training. The attitudes and practices of BHWs are also affected because of deficient knowledge regarding etiology and transmission of HD. There is a need for adequate training and refresher courses on HD to increase the knowledge of BHWs regarding HD.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 17","pages":"8-16"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-09-30eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i17.9208
Amanda T Chung, Jerson N Taguibao, Arunee H Siripunvarapon, Ma Lorna F Frez
{"title":"Cutaneous Squamous Cell Carcinoma and Multiple Basal Cell Carcinomas in Xeroderma Pigmentosum-Variant Type Treated with Imiquimod 5% Cream and Radiotherapy: A Case Report.","authors":"Amanda T Chung, Jerson N Taguibao, Arunee H Siripunvarapon, Ma Lorna F Frez","doi":"10.47895/amp.v58i17.9208","DOIUrl":"10.47895/amp.v58i17.9208","url":null,"abstract":"<p><p>Xeroderma pigmentosum (XP) is a rare DNA repair disorder characterized by sensitivity to sunlight and predisposition to cutaneous malignancies. There are various types, including the Variant type, which does not manifest with acute sunburn reactions. This results to the development of multiple malignancies that are often discovered at late stages, making management more challenging. This is a case of a 54-year-old Filipino female presenting with multiple basal cell carcinomas (BCCs) on several areas of the face and advanced cutaneous squamous cell carcinoma (cSCC) on the right zygomatic area, treated with imiquimod 5% cream and external beam radiation therapy, respectively. There was an excellent response of the BCCs to imiquimod 5% cream and good tumoral response of the SCC to radiation therapy, with tolerable side effects, highlighting the use of these palliative treatment modalities for XP patients with multiple, unresectable, or difficult-to-treat cutaneous malignancies.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 17","pages":"100-105"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-09-30eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i17.8194
Roy Luister C Acos, Marie Len C Balmores, Eileen Liesl A Cubillan
{"title":"Hemosiderotic Dermatofibroma in a Filipino Male.","authors":"Roy Luister C Acos, Marie Len C Balmores, Eileen Liesl A Cubillan","doi":"10.47895/amp.v58i17.8194","DOIUrl":"10.47895/amp.v58i17.8194","url":null,"abstract":"<p><p>Dermatofibroma (DF) is a common, benign fibrohistiocytic tumor with unknown pathogenesis. There are multiple uncommon histologic variants of DF reported in literature, one of which is hemosiderotic DF. It can variably present as a pigmented papule or nodule commonly located on the lower extremities. Hemosiderotic DF remains to be underreported in the Philippines despite the widely available dermatopathology services in the country.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 17","pages":"110-112"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}