Acta Medica PhilippinaPub Date : 2024-10-31eCollection Date: 2024-01-01DOI: 10.47895/amp.vi0.7867
Sean Patrick Catalon de Guzman, Lorelei Legaspi Chavez, Aedrian Arcangel Abrilla
{"title":"Single-arm Cohort Study on the Effects of the COVID-19 Pandemic on the Radiation Treatment of Cancer Patients Referred to the Radiation Oncology Division of a Tertiary Hospital.","authors":"Sean Patrick Catalon de Guzman, Lorelei Legaspi Chavez, Aedrian Arcangel Abrilla","doi":"10.47895/amp.vi0.7867","DOIUrl":"10.47895/amp.vi0.7867","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to identify the effects of COVID-19 pandemic on radiation treatment delays, interruptions, and cancer outcomes if any, in a Philippine tertiary hospital.</p><p><strong>Methods: </strong>A retrospective observational cohort study was conducted among patients living with cancer who were referred for radiation therapy from March to July 2020. Data on treatment delays, treatment interruptions, and average treatment times were collected and analyzed. An association between radiation treatment interruption and disease failure rate was also evaluated.</p><p><strong>Results: </strong>The study found the mean radiation treatment time ranged from 50.3 days to 140.6 days from the start of radiation treatment to the end of radiation treatment, and 181.7 days to 217.3 days from the date of CT simulation to the end of radiation treatment. These radiation treatment times and treatment interruptions are beyond any published recommendations for external beam radiation therapy, thus potentially leading to worse oncologic outcomes. However, no association between treatment interruption and disease failure rate was noted. This may be due to limitations of the study such as small sample size and heterogeneous patient characteristics such as different cancer pathologies and different disease stages.</p><p><strong>Conclusion: </strong>This study showed that the COVID-19 pandemic had a significant impact on radiation treatment interruptions and delays, potentially leading to worse oncologic outcomes. The lack of association between treatment interruption and disease failure rate needs further investigation with a larger sample size, more homogeneous patient characteristics, and longer follow-up. The findings highlight the importance of maintaining cancer care services during pandemics and implementing measures to minimize treatment interruptions and delays to improve cancer outcomes.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 19","pages":"50-55"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-10-31eCollection Date: 2024-01-01DOI: 10.47895/amp.vi0.8215
Raymund F Mamayson, Wyn P Cawalo, Elliz John P Morales, Rhomayne Xyla D Morla, Kayla Louise M Nebrida, Zia Marizz P Orca, Leigh Shamaine R Pacolor, Diana P Paran, Alexandra Ysabelle P Ramos, Ezra Nicole S Razon, Ma Marie Antonette C Sales, Sir Josh Marlowe G Soriano, Alexandra Krisha Danielle I Tagorda, Rex Daniel B Tingson
{"title":"Effects of E-Learning Materials on Caregivers' Knowledge about the 3Ds of Geriatric Psychiatry.","authors":"Raymund F Mamayson, Wyn P Cawalo, Elliz John P Morales, Rhomayne Xyla D Morla, Kayla Louise M Nebrida, Zia Marizz P Orca, Leigh Shamaine R Pacolor, Diana P Paran, Alexandra Ysabelle P Ramos, Ezra Nicole S Razon, Ma Marie Antonette C Sales, Sir Josh Marlowe G Soriano, Alexandra Krisha Danielle I Tagorda, Rex Daniel B Tingson","doi":"10.47895/amp.vi0.8215","DOIUrl":"10.47895/amp.vi0.8215","url":null,"abstract":"<p><strong>Background: </strong>E-learning has emerged as a crucial technique that educators embrace and apply. Two effective e-learning materials are video-based learning (VBL) and e-book-based remote learning (EBRL). While several studies have proven their effectiveness, none have compared these e-learning materials, especially regarding caregivers' knowledge of delirium, dementia, and depression (3Ds). Based on the extant literature, many caregivers are untrained and often lack the knowledge and skills to lessen the burden on delirious, demented, and depressed older adults. Hence, there is a growing need to explore how e-learning materials will address caregivers' lack of knowledge about the 3Ds of geriatric psychiatry.</p><p><strong>Objectives: </strong>This study ascertained the effects of e-learning materials on caregivers' knowledge about the 3Ds of geriatric psychiatry and determined significant differences within and between groups.</p><p><strong>Methods: </strong>A three-arm, quasi-experimental study, which included 63 informal caregivers in Baguio City who met the inclusion criteria and were chosen through purposive sampling, was conducted. Data were gathered using the Delirium-related knowledge tool, the Bangladesh version of the Depression Literacy Questionnaire, and the Dementia Knowledge Assessment Tool version 2. Data collection was done face-to-face and was conducted from March to April 2023. Data were treated with descriptive and inferential statistics using means, paired t-test, one-way omnibus ANOVA, and the post hoc Scheffé's test. Ethics approval was provided by the Saint Louis University Research Ethics Committee (SLU-REC-UG 2023-004).</p><p><strong>Results: </strong>All the pretest mean scores of respondents in the VBL, EBRL, and control groups increased in the posttest. Additionally, the paired t-test revealed that the VBL and EBRL materials significantly affected the caregivers' knowledge about the 3Ds of geriatric psychiatry, evidenced by a t-statistic of -5.80 (p=0.00001) and -4.48 (p= 0.00023), respectively. Lastly, one-way ANOVA revealed that there was a statistically significant difference in mean scores between at least two groups (F(2,60) = [7.060], p=0.002). Post hoc analysis using Scheffé's test for multiple comparisons found that the mean values significantly differed between the VBL and the waitlist control group (Scheffé=10.589), and between the EBRL and the waitlist control group (Scheffé=10.589). There was no statistically significant difference between the VBL and the EBRL groups (Scheffé=0).</p><p><strong>Conclusions: </strong>This study suggests that informal caregivers in Baguio City are moderately knowledgeable about the 3Ds of geriatric psychiatry. Moreover, both VBL and EBRL materials showed effectiveness in improving caregivers' knowledge about the 3Ds of geriatric psychiatry, highlighting the substantial equivalence of both materials. Lastly, caregivers' knowledge about the 3Ds of geriatric psychia","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 19","pages":"18-28"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-10-31eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i19.11986
Shelley F Dela Vega
{"title":"E-Learning Modules for the Care of Caregivers of Older Filipinos.","authors":"Shelley F Dela Vega","doi":"10.47895/amp.v58i19.11986","DOIUrl":"10.47895/amp.v58i19.11986","url":null,"abstract":"","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 19","pages":"7-8"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-10-31eCollection Date: 2024-01-01DOI: 10.47895/amp.v58i19.11983
Wilfredo Ii Francis F Mina
{"title":"Navigating the Stream: Empowering Filipinos in their Mental Health Journey.","authors":"Wilfredo Ii Francis F Mina","doi":"10.47895/amp.v58i19.11983","DOIUrl":"10.47895/amp.v58i19.11983","url":null,"abstract":"","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 19","pages":"5-6"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-10-31eCollection Date: 2024-01-01DOI: 10.47895/amp.vi0.8002
Richelle Ann M Manalo-Cabalinan, Gerwin Louis T Dela Torre, Angelina A Atienza, Erna C Arollado
{"title":"<i>Carica papaya</i> Flower Extracts Possess Antioxidant and 5α-reductase Inhibitory Activities.","authors":"Richelle Ann M Manalo-Cabalinan, Gerwin Louis T Dela Torre, Angelina A Atienza, Erna C Arollado","doi":"10.47895/amp.vi0.8002","DOIUrl":"10.47895/amp.vi0.8002","url":null,"abstract":"<p><strong>Objectives: </strong><i>Carica papaya</i> has been widely used commercially for skin care due to its therapeutic benefits. The potential of its flower to promote hair growth has been traditionally recognized in other countries but not in the Philippines. In this study, we explored the effect of various extracts of <i>C. papaya</i> flower in the biological activities associated with hair loss, including 5α-reductase inhibition and antioxidation, as well as identified the putative compounds present in the most potent extract.</p><p><strong>Methods: </strong>The flowers of <i>C. papaya</i> were macerated separately with ethanol, ethyl acetate, and hexane to obtain their corresponding crude extracts. These extracts were subjected to antioxidant tests via 2,2'-diphenyl-1-picrylhydrazyl (DPPH), and ferric-reducing antioxidant power (FRAP) assays. The total phenolic and flavonoid contents (TPC and TFC) of the crude extracts were determined, as well as the ability of the extracts to inhibit 5α-reductase. The compounds present in the most potent extract were determined using ultraperformance liquid chromatography quadrupole time of flight mass spectrometer (UPLC/MS-QToF).</p><p><strong>Results: </strong>Ethyl acetate extract displayed significantly higher DPPH activity (0.001755 ± 0.00092 ascorbic acid equivalent antioxidant capacity) and 5α-reductase inhibitory activity (115.18 ± 11.61 mg dutasteride/g) compared to ethanol (DPPH: <i>p</i>=0.0121; 5α-reductase: <i>p</i>=0.0016) and hexane (DPPH: <i>p</i>=0.0038; 5α-reductase: <i>p<</i>0.0001) extracts. Similarly, ethyl acetate extract gave the highest FRAP (0.4842 ± 0.0936 mg ascorbic acid/g) activity, TFC (0.0403 mg quercetin/g), and TPC (0.0463 mg gallic acid/g) among the extracts. Forty-nine compounds were annotated in the ethyl acetate extract, with seven (7) putatively identified as fatty acids (9-hydroxy-10,12-pentadecadienoic acid, 9,12,15-octadecatrienoic acid), hydroxyflavone (5-methylkaempferol), alkaloid (allomatrine), dipeptide derivative (aurantiamide acetate), bufotalinin, and 6β-acetoxy-5-epilimonin based on the Traditional Chinese Medicine Library.</p><p><strong>Conclusion: </strong>These results suggest that local <i>C. papaya</i> flowers can be a source of hair growth-promoting agents via their antioxidant and 5α-reductase inhibitory potential.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 19","pages":"83-92"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-10-31eCollection Date: 2024-01-01DOI: 10.47895/amp.vi0.7369
Ana Sarahi Mulia Soto, Miriam Deyanira Rodríguez Piña, Acela Marlen Santamaría Benhumea, Hugo Mendieta Zerón
{"title":"Use of Renal Replacement Therapy in Pregnant Women with Acute Kidney Injury or Chronic Kidney Disease: A Systematic Review.","authors":"Ana Sarahi Mulia Soto, Miriam Deyanira Rodríguez Piña, Acela Marlen Santamaría Benhumea, Hugo Mendieta Zerón","doi":"10.47895/amp.vi0.7369","DOIUrl":"10.47895/amp.vi0.7369","url":null,"abstract":"<p><strong>Objectives: </strong>Acute Kidney Injury (AKI) during pregnancy is a complication that poses a serious risk of life for the mother and the fetus. In most cases, the treatment considered in the first instance is pregnancy interruption with subsequent conventional treatment of AKI. The aim of this review is to describe the risks and benefits of using renal replacement therapy [peritoneal dialysis (PD) and hemodialysis (HD)] in pregnant patients with AKI.</p><p><strong>Methods: </strong>A systematic review of pregnant women with AKI/CKD on RRT (pointing out the results of maternal and neonatal morbidity and mortality) in the last three decades was done between January and March 2021 using the databases Pubmed, LILACS, Cochrane, Tripdatabase, AJKD, and Elsevier. Articles in Spanish, English, and French languages were included. A summary of cases of pregnant women on RRT with women and fetus survival percentages was shown in a table.</p><p><strong>Results: </strong>Making a summary of all the included patients, it resulted in 1673 women, 1208 in HD and 170 in PD with 15 maternal deaths and survival percentages for the fetus of 74% in HD and 40% in PD.</p><p><strong>Conclusion: </strong>The RRT in pregnant women with AKI/CKD offers a high survival rate for the women and fetus.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 19","pages":"101-108"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-10-31eCollection Date: 2024-01-01DOI: 10.47895/amp.vi0.8005
Gerwin Louis T Dela Torre, Richelle Ann M Manalo, Szarina Krisha K Ko, Erna C Arollado, Arlene A Samaniego
{"title":"<i>Lactobacillus brevis</i> BIOTECH 1766 Attenuates Oxidative Stress and Histopathological Changes following Aluminum Poisoning in ICR Mice.","authors":"Gerwin Louis T Dela Torre, Richelle Ann M Manalo, Szarina Krisha K Ko, Erna C Arollado, Arlene A Samaniego","doi":"10.47895/amp.vi0.8005","DOIUrl":"10.47895/amp.vi0.8005","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the protective effects of <i>Lactobacillus brevis</i> BIOTECH 1766 against oxidative damage in the brain, liver, and kidneys induced by aluminum (Al) poisoning in ICR mice.</p><p><strong>Methods: </strong>Twenty mice were divided into four groups (n = 5): (I) control, (II) Al, (III) citric acid (CA), and (IV) <i>L. brevis</i> BIOTECH 1766 group. A 14-day treatment period was implemented, wherein groups I and II received sterile water, while groups III and IV received 10 mg/kg bw of CA and 1 x 10<sup>9</sup> cfu/kg bw of <i>L. brevis</i> BIOTECH 1766, respectively. On day 15, all except the control group received a single oral dose of 1438 mg/kg bw of AlCl<sub>3</sub> <sup>.</sup>6H<sub>2</sub>O. After 24 h, mice were euthanized to collect the brain, liver, and kidneys for the oxidative stress marker analyses and histopathological examination.</p><p><strong>Results: </strong>Acute intoxication of Al led to a significant increase in tissue malondialdehyde (MDA) and a significant decrease in the tissue's reduced glutathione (GSH), catalase (CAT), and superoxide dismutase (SOD). Mice pretreated with CA or <i>L. brevis</i> BIOTECH 1766 have markedly reduced CAT activity in the liver, and SOD in all three organs. Extensive organ injuries were also prevented by CA and <i>L. brevis</i> BIOTECH 1766 pretreatment, with the latter providing better protection against liver damage.</p><p><strong>Conclusion: </strong>The findings showed that <i>L. brevis</i> BIOTECH 1766 provides a protective effect against acute Al poisoning in mice by ameliorating oxidative damage in the brain, liver, and kidneys.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 19","pages":"56-63"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-10-31eCollection Date: 2024-01-01DOI: 10.47895/amp.vi0.7600
Jay T Dalet, Jose Kenneth T Narag, Arnold V Hallare, Francisco T Heralde
{"title":"Effects of <i>Apis dorsata</i> Honey on the mRNA Expression of Selected <i>CYP450</i>, Pro-apoptotic, and Anti-apoptotic Genes during Induced Cytotoxicity in Cyclophosphamide-treated Human Lung Carcinoma (A549) Cells.","authors":"Jay T Dalet, Jose Kenneth T Narag, Arnold V Hallare, Francisco T Heralde","doi":"10.47895/amp.vi0.7600","DOIUrl":"10.47895/amp.vi0.7600","url":null,"abstract":"<p><strong>Introduction: </strong>One of the novel strategies in cancer treatment is the combination of conventional chemotherapeutic drugs and natural products. In a previous study, co-treatment of the anti-cancer drug cyclophosphamide (CP) with honey from giant honey bee (<i>Apis dorsata</i>) resulted to a dose-dependent increase in its cytotoxic effect in human lung carcinoma (A549) cells. However, the molecular mechanism of this combinatorial effect remains unknown.</p><p><strong>Objectives: </strong>In this study, the effect of <i>A. dorsata</i> honey on the expression of selected CYP450 genes at the mRNA level, as well as the proapoptotic gene <i>CASP8</i> and antiapoptotic gene <i>BCL2</i> was investigated in CP-treated A549 cells.</p><p><strong>Methods: </strong>MTT Assay was performed to determine the cell viability of A549 cells after treatment with CP with or without <i>A. dorsata</i> honey, as well as the EC<sub>50</sub> of CP with honey thereafter. RT-qPCR was then performed to study the effect of <i>A. dorsata</i> honey on the expression of selected CYP450 genes as well as <i>CASP8</i> and <i>BCL2</i> genes in CP-treated A549 cells. LC-MS was carried out to screen for putative compounds in <i>A. dorsata</i> honey which may possibly have anti-cancer activity.</p><p><strong>Results: </strong>Honey in the lowest concentration (0.6% v/v) most effectively enhanced the cytotoxic effect of CP. <i>CYP2J2</i> and <i>CYP1B1</i> indicated a 2.38-fold and 1.49-fold upregulation, respectively as compared to untreated cells. This cytotoxic effect is further enhanced by upregulation of <i>CASP8</i> that is paralleled by a downregulation of <i>BCL2</i>. Phytosphingosine and sphinganine are honey constituents which may be linked to the increased cytotoxicity of CP observed in A549 cells.</p><p><strong>Conclusion: </strong>This study provides further knowledge on the molecular basis by which <i>A. dorsata</i> honey potentiates the cytotoxic effect of cyclophosphamide in A549 cells.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 19","pages":"37-49"},"PeriodicalIF":0.0,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11586291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-10-15eCollection Date: 2024-01-01DOI: 10.47895/amp.vi0.9460
Karl Matthew C Sy Su, Ivan Gil P Balmadrid
{"title":"Outcomes of Peripheral Nerve Blocks in Elderly Patients with Fragility Hip Fractures in the Philippine General Hospital: A 6-month Prospective Study.","authors":"Karl Matthew C Sy Su, Ivan Gil P Balmadrid","doi":"10.47895/amp.vi0.9460","DOIUrl":"10.47895/amp.vi0.9460","url":null,"abstract":"<p><strong>Background and objective: </strong>Hip fractures among the elderly continue to be a serious public health concern. Hip fractures result in extremely painful injuries and given the higher risk of the elderly for complications, managing pain in this population can be challenging. This study aimed to describe the outcomes of peripheral nerve blocks on elderly patients with fragility hip fractures who will undergo elective or emergency hip surgery.</p><p><strong>Methods: </strong>A single-center prospective cohort study was conducted at the Philippine General Hospital from May 2022 to November 2022. Patients included were aged 60 years old and above with fragility hip fracture, for elective or emergency hip surgery, and with American Society of Anesthesiologists (ASA) Physical Status Score 1-3. Patients' baseline profile, intraoperative characteristics, and postoperative outcomes were collected using a standard data collection form. The data collector was blinded to the type of block performed.</p><p><strong>Results: </strong>A total of 29 patients who underwent hip surgery were included in the study. Most (65.5%) had Subarachnoid block + Peripheral Nerve Block (SAB+PNB) while 24.1% had General Anesthesia + Peripheral Nerve Block (GA+PNB) and 10.3% had no Peripheral Nerve Block (PNB). The median Numerical Rating Scale (NRS) 30 minutes post block was similar (p=0.977) in those who had PNB blocks (GA+PNB = 0, SAB+PNB = 0). The median NRS at rest during Postoperative day 1 (POD1) was significantly highest (p=0.023) in the No PNB group (3) than in both GA+PNB (0) and SAB+PNB (0). In contrast, the median NRS at rest during POD2 was similar (p=0.713) in the three groups (GA+PNB = 0, SAB+PNB = 0, No PNB = 0). The median NRS at motion during POD1 was significantly highest (p=0.008) in the No PNB group (6) than in both GA+PNB (0) and SAB+PNB (1). Also, the median NRS at motion during POD2 was significantly highest (p=0.009) in No PNB group (4) than in both GA+PNB (0) and SAB+PNB (1). Median Morphine Milligram Equivalent (MME) of postoperative opioid was significantly higher in the No PNB group among the three groups (p=0.047). The median satisfaction score (p=0.210), median delirium score at POD2 (p=0.993), and median length of hospitalization (p=0.173) were all similar in the three groups.</p><p><strong>Conclusion: </strong>Peripheral nerve block is effective in elderly patients undergoing surgery for fragility hip fractures. It results in lower pain scores and can be administered with equal effectiveness either with general anesthesia or with subarachnoid block. Mortality rate, incidence of delirium, and hospital length of stay did not vary between those with and without peripheral nerve block.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 18","pages":"49-55"},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142556876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta Medica PhilippinaPub Date : 2024-10-15eCollection Date: 2024-01-01DOI: 10.47895/amp.vi0.8551
Jonah Mikka B Dorado, Leonila F Dans, Carol Stephanie C Tan-Lim, Cara Lois T Galingana, Janelle Micaela S Panganiban, Mia P Rey, Josephine T Sanchez, Herbert S Zabala, Maria Rhodora N Aquino, Antonio L Dans
{"title":"Frequency Distribution of Pediatric Primary Care Cases in a Rural Site in The Philippines: A Cross-Sectional Study.","authors":"Jonah Mikka B Dorado, Leonila F Dans, Carol Stephanie C Tan-Lim, Cara Lois T Galingana, Janelle Micaela S Panganiban, Mia P Rey, Josephine T Sanchez, Herbert S Zabala, Maria Rhodora N Aquino, Antonio L Dans","doi":"10.47895/amp.vi0.8551","DOIUrl":"10.47895/amp.vi0.8551","url":null,"abstract":"<p><strong>Background: </strong>Primary care for pediatric patients focuses on providing comprehensive, accessible, and coordinated healthcare from the neonatal period to adolescence. The implementation and use of electronic medical records (EMR) in pediatric primary care facilities is an efficient strategy to gather necessary information on the epidemiology of common pediatric diseases in the Philippines.</p><p><strong>Objectives: </strong>This study aimed to determine the frequency distribution of pediatric diseases in a rural primary healthcare facility in the Philippines.</p><p><strong>Methods: </strong>This cross-sectional study reviewed the EMR of all pediatric patients who consulted in a primary care facility in Samal, Bataan from April 2019 to March 2021. Data gathered include sex, age in years, chief complaint, diagnosis, and month of consultation. Data was summarized using descriptive statistics.</p><p><strong>Results: </strong>A total of 14,462 pediatric consults were recorded from April 2019 to March 2021. There were slightly more male patients (52.1%). The mean age of the patients was 6.5 years (standard deviation 5.22). The highest number of consults came from the 1- to 4-year-old age group (41.5%). The most common chief complaints were cough (45.9%), fever (25.5%), and colds (24.9%). The most frequent diagnoses were upper respiratory tract infections (47.4%), followed by lower respiratory tract infections (6.9%), and skin and soft tissue infections (5.3%). Majority of the consults for respiratory tract infections, skin and soft tissue infections, gastroenteritis, asthma, and dermatitis were in the 1- to 4-year-old age group. Urinary tract infections and otitis media or externa were recorded more frequently in the 5- to 9-year-old age group.</p><p><strong>Conclusions: </strong>Respiratory tract infections, followed by skin and soft tissue infections, were the most frequently identified diseases in children consulting a primary care facility at a rural site in the Philippines. The most common chief complaints, defined as the primary reason for seeking consult, were cough, fever, and colds. Data was gathered through EMR review, which may aid in the planning of programs and policies to improve primary care service delivery.</p>","PeriodicalId":6994,"journal":{"name":"Acta Medica Philippina","volume":"58 18","pages":"71-78"},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142556875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}