中国医学科学院学报最新文献_第2页

Application of Multi-Model Adaptive Statistical Iterative Reconstruction-Veo in Ultra-Low Dose Chest CT Examination of Children in Plateau Area. 多模型自适应统计迭代重建-Veo在高原地区儿童超低剂量胸部CT检查中的应用

中国医学科学院学报 Pub Date : 2025-02-01 DOI: 10.3881/j.issn.1000-503X.16068

Xian-Tao Wang, Rui-Ting Bai, Cidanwangjiu, Suolangnima, Nimazhuoga, Bai-Yan Su

{"title":"Application of Multi-Model Adaptive Statistical Iterative Reconstruction-Veo in Ultra-Low Dose Chest CT Examination of Children in Plateau Area.","authors":"Xian-Tao Wang, Rui-Ting Bai, Cidanwangjiu, Suolangnima, Nimazhuoga, Bai-Yan Su","doi":"10.3881/j.issn.1000-503X.16068","DOIUrl":"10.3881/j.issn.1000-503X.16068","url":null,"abstract":"Objective To explore the application value of multi-model adaptive statistical iterative reconstruction-Veo (ASiR-V) in ultra-low dose chest CT examination of children in the plateau area. Methods The children who underwent chest CT examination in Xizang Autonomous Region People's Hospital were enrolled in this study and assigned into two groups according to the scanning conditions.Group A underwent scanning at a tube voltage of 100 kV and ASiR-V 50% reconstruction,and group B underwent scanning at a tube voltage of 80 kV and ASiR-V 0 (Group B1) and ASiR-V 50% (Group B2) reconstruction.The image quality of each group was evaluated objectively and subjectively.The radiation dose and image quality were compared between groups. Results Groups A and B showed the volume CT dose indexes of (2.33±0.62) mGy and (0.86±0.01) mGy and the dose length products of (65.01±25.12) mGy·cm and (23.55±3.38) mGy·cm,respectively,which presented differences between groups (both P<0.001).The image noise in the bilateral upper and middle lung areas in group B2 was lower than that in group B1 but higher than that in group A (all P<0.001).There was no significant difference in image quality score of the lung window among groups (all P>0.05).Groups A,B1,and B2 had no significant differences in ascending aorta (P=0.538) or liver CT value (P=0.175) in the mediastinal window.The signal-to-noise ratios and contrast-to-noise ratios of ascending aorta and liver in group B2 were higher than those in group B1 (all P<0.001) and lower than those in group A (all P<0.05).The image quality score of the mediastinal window followed a descending order of group A>group B2>group B1 (all P<0.001)。Conclusion ASiR-V combined with low tube voltage can effectively reduce the radiation dose and guarantee the image quality of chest CT of children in the plateau area.","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":" ","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experience and Implications on Advance Medical Directives in Hong Kong.

中国医学科学院学报 Pub Date : 2025-02-01 DOI: 10.3881/j.issn.1000-503X.16193

Gao Xiao-Yi

引用次数: 0

Cellular and Histopathological Characteristics of Ultrasonically Underdiagnosed 3/4a Thyroid Nodules.

中国医学科学院学报 Pub Date : 2025-02-01 DOI: 10.3881/j.issn.1000-503X.16040

W U Wei-Qi, X U Cun-Bao, L I You-Jia, S U Chun-Yang, Zhang Feng-Shun, Chen Yi-Feng

{"title":"Cellular and Histopathological Characteristics of Ultrasonically Underdiagnosed 3/4a Thyroid Nodules.","authors":"W U Wei-Qi, X U Cun-Bao, L I You-Jia, S U Chun-Yang, Zhang Feng-Shun, Chen Yi-Feng","doi":"10.3881/j.issn.1000-503X.16040","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.16040","url":null,"abstract":"Objective To analyze the cellular and histopathological characteristics of underdiagnosed thyroid nodules of Chinese thyroid imaging reporting and data system(C-TIRADS) categories 3 and 4a,thus improving the understanding of these lesions. Methods The data of ultrasound and fine needle aspiration cytology were collected from 683 nodules diagnosed based on pathological evidence in 549 patients undergoing thyroid surgery.The cellular and histopathological characteristics of C-TIRADS 3 and 4a nodules were analyzed. Results Two hundred and sixty-eight nodules were classified as C-TIRADS category 3,including 236 benign nodules,12 low-risk ones,and 20 (7.46%) malignant ones.Two hundred and twenty-one nodules were classified as C-TIRADS category 4a,including 133 benign nodules,7 low-risk ones,and 81 (36.65%) malignant ones.The malignancy rates differed between C-TIRADS 3 and 4a nodules (χ2=58.93,P<0.001),and both were higher than the recommended malignancy rate in the guidelines for malignancy risk stratification of thyroid nodules (C-TIRADS) (both P<0.001).According to the pathological evidence,the underdiagnosed C-TIRADS 3/4a nodules were mainly papillary thyroid carcinoma,especially in patients with Hashimoto thyroiditis.There was not a consistent one-to-one match between each ultrasound result and each cytological classification of low-risk thyroid nodules.Conclusions When the malignant features in preoprative ultrasound imaging are atypical or absent,papillary thyroid carcinoma (especially with Hashimoto thyroiditis),follicular carcinoma,and medullary carcinoma are likely to be underdiagnosed as C-TIRADS 3 or 4a nodules.Therefore,efforts should be made to fully understand the cellular and pathological characteristics of these lesions.","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":"47 1","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Characteristics of Patients With Idiopathic Multicentric Castleman Disease Complicated by Autoimmune Hemolytic Anemia.

中国医学科学院学报 Pub Date : 2025-02-01 DOI: 10.3881/j.issn.1000-503X.16135

Gao Yu-Han, L I Si-Yuan, Dang Yue, L I Jian, Zhang Lu

{"title":"Clinical Characteristics of Patients With Idiopathic Multicentric Castleman Disease Complicated by Autoimmune Hemolytic Anemia.","authors":"Gao Yu-Han, L I Si-Yuan, Dang Yue, L I Jian, Zhang Lu","doi":"10.3881/j.issn.1000-503X.16135","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.16135","url":null,"abstract":"Objective To investigate the clinical characteristics,treatment responses,and prognosis of patients with idiopathic multicentric Castleman disease(iMCD)complicated by autoimmune hemolytic anemia(AIHA). Methods The patients diagnosed with iMCD in Peking Union Medical College Hospital from January 2010 to December 2023 and having complete baseline blood routine data were retrospectively enrolled in the study.The iMCD patients were further assigned into AIHA and non-AIHA groups based on baseline laboratory examinations,and the clinical characteristics and prognosis were compared between the two groups. Results A total of 341 patients with iMCD were enrolled in this study,including 277(81.2%)exhibiting anemia at baseline.Five(1.8%)patients were identified as having iMCD-AIHA,all of whom were iMCD-not otherwise specified type complicated by warm antibody-type AIHA,and two of them were simultaneously diagnosed with Evans syndrome.The timing relationship between the first onset of AIHA and iMCD diagnosis varied,with 2 patients experiencing their first hemolytic episode prior to the diagnosis of iMCD.In terms of treatment,the therapy targeting iMCD was effective in alleviating AIHA.The AIHA group had a poorer prognosis(HR=4.61,95% CI=1.08-19.80,P=0.040)and a lower 5-year survival rate(90% vs.60%,P=0.024)than the non-AIHA group.Conclusions iMCD-AIHA is clinically rare,and AIHA can occur at different stages of iMCD.Although the primary treatment principle remains targeting iMCD,great attention should be paid to the exacerbation of immune dysfunction caused by AIHA and the possible adverse prognosis it may bring.","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":"47 1","pages":"10-15"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lymphatic and Venous Contrast-Enhanced Ultrasound Imaging for Differential Diagnosis of Cervical Lymph Node Metastasis in Thyroid Cancer. 淋巴和静脉对比增强超声成像用于甲状腺癌颈淋巴结转移的鉴别诊断

中国医学科学院学报 Pub Date : 2025-02-01 DOI: 10.3881/j.issn.1000-503X.16120

L I Xu, Wan Wen-Bo, Gao Tian, Gou Tao-Hua, Zhang Yan

{"title":"Lymphatic and Venous Contrast-Enhanced Ultrasound Imaging for Differential Diagnosis of Cervical Lymph Node Metastasis in Thyroid Cancer.","authors":"L I Xu, Wan Wen-Bo, Gao Tian, Gou Tao-Hua, Zhang Yan","doi":"10.3881/j.issn.1000-503X.16120","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.16120","url":null,"abstract":"Objective To investigate the value of the novel lymphatic contrast-enhanced ultrasound(LCEUS)and conventional venous contrast-enhanced ultrasound(VCEUS)in the differential diagnosis of benign and malignant cervical lymph nodes in patients with thyroid cancer. Methods Patients with suspected thyroid cancer underwent conventional ultrasound,VCEUS,and LCEUS examinations of cervical lymph nodes before biopsy.The diagnostic abilities of conventional ultrasound,VCEUS,and LCEUS were compared with pathological results as the golden standard. Results Forty-four patients with 52 lymph nodes were included in the final data.Thirty-eight metastatic lymph nodes were confirmed by pathological results,and 14 were benign.The diagnostic sensitivity,specificity,and accuracy were 97.37%,71.43%,and 90.38% for LCEUS,92.11%,35.71%,and 76.92% for VCEUS,and 94.74%,21.43%,and 75.00% for conventional ultrasound,respectively.The area under the curve of LCEUS analyzed by the receiver operating characteristic curve was greater than that of VCEUS(P=0.020)and conventional ultrasound(P<0.001). Conclusion LCEUS could significantly improve the differential diagnosis of cervical lymph node metastasis in the patients with thyroid cancer,providing a basis for precise clinical treatment.","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":"47 1","pages":"16-22"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research Progress in Effects of Vermiform Appendix on the Occurrence and Development of Diseases Related to Gut-Brain Axis.

中国医学科学院学报 Pub Date : 2025-02-01 DOI: 10.3881/j.issn.1000-503X.16046

M O Shu-Ting, Tian Zhe, Lei Xin, Han Chao, Chen Yu-Hua

引用次数: 0

Thermal Ablation of Pulmonary Nodules by Electromagnetic Navigation Bronchoscopy Combined With Real-Time CT-Based 3D Fusion Navigation:Report of One Case. 通过电磁导航支气管镜结合实时 CT 3D 融合导航对肺结节进行热消融：一例病例的报告。

中国医学科学院学报 Pub Date : 2025-02-01 DOI: 10.3881/j.issn.1000-503X.16198

Yuan Xu, Qun Liu, Chao Guo, Yi-Bo Wang, Xiao-Fang Wu, Chen-Xi Ma, Gui-Ge Wang, Qian-Shu Liu, Nai-Xin Liang, Shan-Qing Li

引用次数: 0

Multiple Organ Dysfunction Syndrome Caused by Human Herpes Virus 6B Infection in Adults:Report of One Case.

中国医学科学院学报 Pub Date : 2025-02-01 DOI: 10.3881/j.issn.1000-503X.16029

Q I Yan, Zhang Hong