中国医学科学院学报最新文献

{"title":"Application of Multi-Model Adaptive Statistical Iterative Reconstruction-Veo in Ultra-Low Dose Chest CT Examination of Children in Plateau Area.","authors":"Xian-Tao Wang, Rui-Ting Bai, Cidanwangjiu, Suolangnima, Nimazhuoga, Bai-Yan Su","doi":"10.3881/j.issn.1000-503X.16068","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.16068","url":null,"abstract":"<p><p>Objective To explore the application value of multi-model adaptive statistical iterative reconstruction-Veo (ASiR-V) in ultra-low dose chest CT examination of children in the plateau area. Methods The children who underwent chest CT examination in Xizang Autonomous Region People's Hospital were enrolled in this study and assigned into two groups according to the scanning conditions.Group A underwent scanning at a tube voltage of 100 kV and ASiR-V 50% reconstruction,and group B underwent scanning at a tube voltage of 80 kV and ASiR-V 0 (Group B1) and ASiR-V 50% (Group B2) reconstruction.The image quality of each group was evaluated objectively and subjectively.The radiation dose and image quality were compared between groups. Results Groups A and B showed the volume CT dose indexes of (2.33±0.62) mGy and (0.86±0.01) mGy and the dose length products of (65.01±25.12) mGy·cm and (23.55±3.38) mGy·cm,respectively,which presented differences between groups (both P<0.001).The image noise in the bilateral upper and middle lung areas in group B2 was lower than that in group B1 but higher than that in group A (all P<0.001).There was no significant difference in image quality score of the lung window among groups (all P>0.05).Groups A,B1,and B2 had no significant differences in ascending aorta (P=0.538) or liver CT value (P=0.175) in the mediastinal window.The signal-to-noise ratios and contrast-to-noise ratios of ascending aorta and liver in group B2 were higher than those in group B1 (all P<0.001) and lower than those in group A (all P<0.05).The image quality score of the mediastinal window followed a descending order of group A>group B2>group B1 (all P<0.001). Conclusion ASiR-V combined with low tube voltage can effectively reduce the radiation dose and guarantee the image quality of chest CT of children in the plateau area.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Research on Application of Quantitative CT in Clinical Diagnosis and Treatment of Osteoporosis.","authors":"Ning Xia, Dong-Fa Liao, Xiang-Wei Li, Da Liu","doi":"10.3881/j.issn.1000-503X.16035","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.16035","url":null,"abstract":"<p><p>Quantitative CT (QCT) is a method of measuring bone mineral density (BMD) of human based on a CT machine,calibrated by QCT body model and analyzed by professional software.Compared with dual-energy X-ray absorptiometry,QCT can not only assess the cortical and cancellous BMD but also exclude the influences of osteophytes and aortic/vascular calcification,thus being capable of accurately reflecting patients' bone mass.In recent years,increasing studies on QCT and osteoporosis (OP) have been carried out,and the application of QCT in the diagnosis of OP,evaluation of vertebral bone conditions,prediction of fracture risks,and assessment of anti-OP treatment is garnering increasing attention from researchers at home and abroad.This article reviews the research progress in this field,aiming to provide a reference for the research on QCT in the diagnosis and treatment of OP.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Progress of Drugs in Prevention and Treatment of Nephrolithiasis.","authors":"Sha-Sha Xia, Jun Shen, Kai-Wen Shen, Qiang Wang, Wei-Hu Cen","doi":"10.3881/j.issn.1000-503X.15987","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.15987","url":null,"abstract":"<p><p>With the improvement of people's living standards,the incidence of nephrolithiasis is increasing year by year.Nephrolithiasis poses a serious threat to the patients due to the unclear etiology,complicated composition of stones,and high recurrence rate after surgery.As the research on the pathogenesis and pathophysiology of nephrolithiasis keeps deepening in recent years,researchers have made achievements in the drug treatment,which has become a hot topic for urologists.This paper reviews the advances in the research on the possible formation mechanism and drug-induced litholysis and prevention for nephrolithiasis,aiming to provide theoretical references for subsequent clinical research.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermal Ablation of Pulmonary Nodules by Electromagnetic Navigation Bronchoscopy Combined With Real-Time CT-Based 3D Fusion Navigation:Report of One Case.","authors":"Yuan Xu, Qun Liu, Chao Guo, Yi-Bo Wang, Xiao-Fang Wu, Chen-Xi Ma, Gui-Ge Wang, Qian-Shu Liu, Nai-Xin Liang, Shan-Qing Li","doi":"10.3881/j.issn.1000-503X.16198","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.16198","url":null,"abstract":"<p><p>A nodule in the right middle lobe of the lung was treated by a combination of cone-beam CT,three-dimensional registration for fusion imaging,and electromagnetic navigation bronchoscopy-guided thermal ablation.The procedure lasted for 90 min,with no significant bleeding observed under the bronchoscope.The total radiation dose during the operation was 384 mGy.The patient recovered well postoperatively,with only a small amount of blood in the sputum and no pneumothorax or other complications.A follow-up chest CT on the first day post operation showed that the ablation area completely covered the lesion,and the patient was discharged successfully.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Construction and Evaluation of a Risk Prediction Model for Septic Cardiomyopathy Based on MIMIC-Ⅳ Database].","authors":"Bin Xiong, Yin-Zhou Liu, An Zhang","doi":"10.3881/j.issn.1000-503X.16031","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.16031","url":null,"abstract":"<p><p>Objective To analyze the risk factors of septic cardiomyopathy (SC),and to construct and evaluate the risk prediction model of SC. Methods The clinical data of patients with sepsis were extracted from MIMIC-Ⅳ database and randomized into a training set and a validation set at a ratio of 7 to 3.According to the presence or absence of SC,the patients were assigned into SC and non-SC groups.The independent risk factors of SC were determined by univariate and multivariate Logistic regression analysis,and a risk prediction model and a nomogram were established.The area under the receiver operating characteristic curve (AUC),calibration curve,and decision curve analysis (DCA) were employed to evaluate the distinguishing degree,calibration,and clinical applicability of the model,respectively. Results A total of 2628 sepsis patients were enrolled in this study,including 1865 patients in the training set and 763 patients in the validation set.There was no significant difference in the incidence of SC between the training set and the validation set (58.98% <i>vs.</i> 62.25%,<i>P</i>=0.120).Except chronic obstructive pulmonary disease (<i>P</i>=0.015) and length of stay in intensive care unit (<i>P</i>=0.016),there was no significant difference in other clinical indicators between the two groups (all <i>P</i>>0.05).Logistic regression analysis showed that coronary heart disease (<i>P</i>=0.028),heart failure (<i>P</i><0.001),increased neutrophil count (<i>P</i>=0.001),decreased lymphocyte count (<i>P</i>=0.036),increased creatine kinase isoenzyme (<i>P</i><0.001),and increased blood urea nitrogen (<i>P</i>=0.042) were independent risk factors for SC.The AUC of the nomogram prediction model in the training set and validation set was 0.759 (95% <i>CI</i>=0.732-0.785) and 0.765 (95% <i>CI</i>=0.723-0.807),respectively.The established model showcased good fitting degrees in both data sets (training set:<i>P</i>=0.075;validation set:<i>P</i>=0.067).The DCA results showed that the nomogram prediction model had good clinical applicability. Conclusion The nomogram prediction model based on basic diseases and clinical biochemical indicators can effectively predict the risk of SC occurrence.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":"46 5","pages":"671-677"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Construction of a Continuous Nursing Quality Evaluation Indicator System for Inflammatory Bowel Disease Patients Based on Donabedian's Three-Dimensional Quality Structure].","authors":"Gai-Rong Ma, Xin-Xian Zhao, Hui-Qin Xi, Ying Ju, Chun-Feng Ruan, Mei Xu, Jing-Jing Wang","doi":"10.3881/j.issn.1000-503X.16028","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.16028","url":null,"abstract":"<p><p>Objective To construct a continuous nursing quality evaluation indicator system for inflammatory bowel disease patients and provide a basis for the evaluation of continuous nursing quality. Methods On the basis of Donabedian's three-dimensional (structure,process,and outcome) quality structure,we employed literature review,qualitative interview,Delphi method,and hierarchical analysis to determine the content and weights of indicators of continuous nursing quality for the patients with inflammatory bowel disease. Results A total of 15 experts completed 2 rounds of consultation,which had the questionnaire recovery rates of 100%,the expert authority coefficients of 0.930 and 0.919,and the Kendall harmony coefficients of 0.149 and 0.177 (both <i>P</i><0.001),respectively.The established nursing quality evaluation indicator system included 3 first-level indicators,10 second-level indicators,and 39 third-level indicators. Conclusion The continuous nursing quality evaluation indicator system for the patients with inflammatory bowel disease that was constructed in this study was reasonable,reliable,and practical,providing reference for evaluating the continuous nursing quality for the patients with inflammatory bowel disease.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":"46 5","pages":"692-699"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Experience of Integrative Palliative Care at Peking Union Medical College Hospital].","authors":"Rui-Xuan Geng, Ying Zheng, Chen-Chen Sun, Xi Zeng, Hong-Yan Fang, Wen-Qian Zhan, Yuan-Feng Yu, Qin Yang, Xiao-Yan Dai, Xiao-Hong Ning","doi":"10.3881/j.issn.1000-503X.16062","DOIUrl":"10.3881/j.issn.1000-503X.16062","url":null,"abstract":"<p><p>Objective To summarize the experience of integrative palliative care at Peking Union Medical College Hospital and provide a reference for promoting the integrative palliative care model. Methods Twenty cases receiving integrative palliative care at Peking Union Medical College Hospital were collected.The clinical characteristics,reasons for initiating integrative palliative care,the process of integrative palliative care,and feedback from these cases were summarized. Results Insomnia (11 cases,55%) and pain (9 cases,45%) were the most common symptoms requiring control in the 20 cases.The integrative palliative care team assisted in medical decision-making for 17 cases (85%),prepared end-of-life for 9 cases (45%),assisted in the transfer for 3 cases (15%),and provided comfort care for all the 20 cases (100%). Conclusions The integrative palliative care model can help alleviate suffering in end-of-life patients and provide support to patients' families and the original medical teams.This model is worth further promotion within class A tertiary hospitals.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":"46 5","pages":"706-710"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Correlations of Ultrasound Features With Gene Mutations and Pathologic Subtypes in Papillary Thyroid Carcinoma].","authors":"Hui-Lin Li, Bo Zhang","doi":"10.3881/j.issn.1000-503X.15845","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.15845","url":null,"abstract":"<p><p>The prognosis of papillary thyroid carcinoma (PTC) is highly dependent on gene mutations and pathologic features.The common gene mutations in PTC include BRAF V600E,RET/PTC rearrangement,and RAS mutations.These mutations have been suggested to be associated with an increased risk of recurrence,poorer efficacy of postoperative radioactive iodine therapy,and reduced survival.The pathologic subtypes of PTC include classic,follicular,tall cell,hobnail,columnar cell,diffuse sclerosing,solid/trabecular,oncocytic,Warthin-like,clear cell,and spindle cell subtypes,which have different aggressiveness and linked with varied clinical prognosis.Therefore,detecting the gene mutations and pathologic subtypes of PTC is of great importance for therapeutic regimen selection and prognosis evaluation.Ultrasound imaging with non-invasiveness,convenience,and high resolution has become the primary examination method for the diagnosis and treatment of thyroid cancer.This paper reviews the correlations of gene mutations and pathologic subtypes with the ultrasound features of PTC,aiming to give new insights into the application of ultrasound imaging in predicting gene mutations and pathologic subtypes of PTC before surgery as well as provide new ideas for accurate assessment of preoperative prognosis.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":"46 5","pages":"747-755"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Erythroderma Complicated With Kaposi Varicelliform Eruption:Report of One Case].","authors":"He Cheng, Zu-Sha Qiao, Yan Ma","doi":"10.3881/j.issn.1000-503X.15886","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.15886","url":null,"abstract":"<p><p>Kaposi varicelliform eruption (KVE) refers to an infectious skin disease that occurs after infection with herpes simplex virus,Coxsackie virus,or other viruses on the basis of preexisting skin diseases,commonly observed in the patients with eczema.It is rare for the patients with erythroderma to be complicated with KVE,and symptoms are often atypical,which pose a challenge to the diagnosis and treatment.This article reports a case of erythroderma complicated with KVE,aiming to raise awareness of clinicians in treating this disease.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":"46 5","pages":"788-791"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Thyroid Hormone Resistance Syndrome Complicated With Papillary Thyroid Carcinoma and Madelung's Disease:Report of One Case].","authors":"Xiao-Han Ma, Rui-Qi Liu, Xue Chen, Ru-Xing Zhao, Qin He, Ming Dong","doi":"10.3881/j.issn.1000-503X.15913","DOIUrl":"https://doi.org/10.3881/j.issn.1000-503X.15913","url":null,"abstract":"<p><p>Thyroid hormone resistance syndrome complicated with papillary thyroid cancer is clinically rare.Madelung's disease is a rare disorder of lipid metabolism.We analyzed the clinical data of a case of thyroid hormone resistance syndrome complicated with papillary thyroid carcinoma and Madelung's disease,performed whole-exon sequencing for the patient's peripheral blood samples,and retrospectively analyzed the relevant literature.This review is expected to provide experience for clinical diagnosis and treatment.</p>","PeriodicalId":6919,"journal":{"name":"中国医学科学院学报","volume":"46 5","pages":"783-787"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}