中华整形外科杂志最新文献

{"title":"[Clinical application of orbital fat autograft for tear trough deformity through tranconjunctival approach].","authors":"Zhibing Ma,&nbsp;Gang Chen,&nbsp;Jinlong Huang,&nbsp;Jinming Wang,&nbsp;Wenting Huang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To discuss the orbital fat autograft for lower baggy eyelid with tear trough deformity and its therapeutic effect through tranconjunctival approach.</p><p><strong>Methods: </strong>The patients with lower eyelid bag and tear trough deformity were included into the study. The included 32 patients met the following criterias: ①less than 40 years old;②lower eyelid skin was not relaxed;③less than 1 s in Snap test; ④ Hirmand type Ⅰ and Ⅱ. They were treated with tranconjunctival lower blepharoplasty combined with the tears ligament relaxation. The orbital fat was repositioned on the depression site above orbital periosteum to correct tear trough deformity. The effect was evaluated through Tear Trough Rating Scale (TTRS) and satisfaction degree.</p><p><strong>Results: </strong>Three cases with Hirmand type Ⅱ didn't have good effect. Among them, the baggy eyelid was corrected in 2 cases, while the tear trough deformity need additional hyaluronic acid injection. One patient underwent secondary lower blepharoplasty through cutaneous incision. Good effect was achieved in the other 29 cases with no depression deformity and eyelid withdrawal. The TTRS scores 6 months after operation was significantly improved(P ＜ 0.01).Satisfaction degree was 100％ (14/14) and 83.3％ (15/18) in type Ⅰ and Ⅱ patients.</p><p><strong>Conclusions: </strong>The technique can simultaneously improve lower eyelid bag and the tear trough deformity. It can be applied in periorbital rejuvenation for middle-aged and young patients.</p>","PeriodicalId":69147,"journal":{"name":"中华整形外科杂志","volume":"33 2","pages":"116-9"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36365944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Thinning of the free muscle flaps for the treatment of hand and foot defects].","authors":"Jianwu Chen,&nbsp;Baoqiang Song,&nbsp;Chen Chen,&nbsp;Dongliang Zhang,&nbsp;Na Wang,&nbsp;Xianjie Ma,&nbsp;Shuzhong Guo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the feasibility of one-stage thinning of latissimus dorsi muscle, rectus abdominis muscle and gracilis flap in reconstruction of the hand and foot defects.</p><p><strong>Methods: </strong>From June 2009 to April 2015,24 free muscle flaps were thinned during transfer operation by removing their superficial muscle layers on the basis of their vessel pedicles running in the deep surface of flaps. The surface of the muscle flaps were covered by split-thickness skin grafts. There were 16 latissimus dorsi muscle flaps,4 gracilis flaps and 4 rectus abdominis muscle flaps. Flap size ranged from 6 cm × 4 cm to 20 cm × 12 cm. Thinned muscle flaps were used to resurface 7 hand defects and 17 foot defects.</p><p><strong>Results: </strong>All muscle flaps survived the thinning procedures without any circulation problems except for one case which suffered total flap necrosis due to venous thrombosis. Skins grafts on muscle flaps also took well. One patient experienced partial skin loss. Two patients underwent secondary debridement and thinning procedure for infection and bulkiness. During the 0.3-20 months follow-up, the contour of thinned muscle flaps matched well with the recipient areas. Reconstructed feet are able to wear regular shoes.</p><p><strong>Conclusions: </strong>Intraoperative immediate thinning of free muscle flaps can be safely accomplished during the primary reconstruction procedure. This procedure prevents the limitations of muscle flap bulkiness and may provide an alternative for surface coverage.</p>","PeriodicalId":69147,"journal":{"name":"中华整形外科杂志","volume":"33 2","pages":"112-5"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36365945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[One-stage reconstruction of distal urethra with free graft of tublar oral mucosa ].","authors":"Yong Tang,&nbsp;Yangqun Li,&nbsp;Muxin Zhao,&nbsp;Zhe Yang,&nbsp;Ning Ma,&nbsp;Weixin Wang,&nbsp;Lisi Xu,&nbsp;Zuo Feng,&nbsp;Jiangting Chen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Objective To investigate the therapeuctic effect of one-stage reconstruction of distal urethra with free graft of tublar oral mucosa. .</p><p><strong>Methods: </strong>Two strips of oral mucosa graft(0.4-0.6 cm in width),were harvested and sutured around an oiled silk roll to form mucosa tube. The mucosa tube was used to reconstruct distal urethra. Postoperative pressure dressing and earlier urination were recommended</p><p><strong>Results: </strong>From May 2007 to October 2015,16 cases with distal urethra defect or stenosis were treated with this method. The urethra defect was 2-4 cm in length. Urethral fistula happened in 3 patients. All the other 13 cases healed primarily.10 cases were followed up for 1-5 years by telephone with normal function.</p><p><strong>Conclusions: </strong>One-stage reconstruction with free graft of bulbar oral mucosa is suitable and reliable for distal urethra defect less than 4 cm in length.</p>","PeriodicalId":69147,"journal":{"name":"中华整形外科杂志","volume":" ","pages":"34-6"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36366076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The effects of down-regulated ITGB5 expression on the proliferation of keloid fibroblasts].","authors":"Tongtong Yang,&nbsp;Minliang Chen,&nbsp;Kui Ma,&nbsp;Xiaobing Fu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To explore the effects of down-regulated ITGB5 expression on the proliferation of keloid fibroblasts and clarify the possible role of β5-integrin (ITGB5) in keloid.</p><p><strong>Methods: </strong>Construct lentiviral sh-RNA-expression vector targeting ITGB5 and infect keloid fibroblasts, the expression of ITGB5 were detected by Western Blot, the proliferation ability was identified by MTT.</p><p><strong>Results: </strong>The expression quantity of ITGB5 mRNA and protein in KFb group,LV-NC group and LV-KFb group are 1.00 ± 0.00,1.08 ±0.05,0.34 ±0.01 and 0.91 ±0.03,0.93 ±0.02,0.28 ±0.07.Compared with LV-NC group and KFb group, the expression quantity of ITGB5 mRNA and protein in LV-KFb group decreased significantly (P ＜ 0.01).Compared with LV-NC group and KFb group,the proliferation rate decreased significantly in LV-KFb group at 48 h(P ＜ 0.01).</p><p><strong>Conclusions: </strong>These results suggest that ITGB5 can accelerate fibroblasts proliferation in keloids.</p>","PeriodicalId":69147,"journal":{"name":"中华整形外科杂志","volume":" ","pages":"49-52"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36366506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Repair of the preauricular defects by the superficial temporal artery frontal branch flap and the retrograde retroauricular artery flap].","authors":"Kaizuo Nie,&nbsp;Wei Chen,&nbsp;Zairong Wei,&nbsp;Guangfeng Sun,&nbsp;Xueqin Zeng,&nbsp;Chenglan Yang,&nbsp;Jianping Qi,&nbsp;Wenhu Jin,&nbsp;Shujun Li","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the feasibility and effectiveness of the superficial temporal artery frontal branch flap combine with the retrograde retroauricular artery flap in repairing the preauricular defects.</p><p><strong>Methods: </strong>The superficial temporal artery frontal branch flap with hair is designed for sideburns reconstruction, and the hairless retrograde retroauricular artery flap for repair the hairless area which is between the tragus and the temples.The donor sites were closed directly.</p><p><strong>Results: </strong>From September 2012 to September 2015,9 cases were treated. All flaps survived completely.Surgical incisions and wounds at donor sites and recipient sites healed primarily. All cases were followed up for 6-18 months (10 months on average) and cosmetic results were satisfactory without visible scar.</p><p><strong>Conclusions: </strong>The method of the superficial temporal artery fiontal branch flap combined with the retrograde retroauricular artery flap for the repair of preauricular a large skin defect is simple with less and inconspicious auxiliary incision. The sidebums and hairless area can be simultaneously reconstructed with satisfactory appearance.</p>","PeriodicalId":69147,"journal":{"name":"中华整形外科杂志","volume":" ","pages":"8-11"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36366070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Effects of PRX-2 gene on the phenotype changes of epidermal stem cells differentiating into sweat gland cells].","authors":"Fuzuo Chen,&nbsp;Huifeng Song,&nbsp;Ximin Guo,&nbsp;Xiaotong Yue,&nbsp;Lingying Liu,&nbsp;Yong Zhou,&nbsp;Donghua Liu,&nbsp;Zhiyong Qian,&nbsp;Tongmin Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effects of PRX-2 gene on phenotype changes in epidermal stem cells differentiating into sweat gland cells.</p><p><strong>Methods: </strong>Epidermal stem cells and sweat gland cells separated and cultured from healthy foreskin and adult full-thick skin respectively, were identified by immunofluorescence staining. Lentiviral vector-mediated overexpression and knockdown of PRX-2 gene in epidermal stem cells were performed respectively,with empty vector-mediated epidermal stem cells as a control group. Overexpression blank control and know down group's PRX-2 expressions in gene and protein levels were detected using RT-PCR and Western blot technology. The ESCs of each group were co-cultured with sweat gland cells through transwell plate, and the expressions of CEA and β1 integrin in epidermal stem cells were determined by flow cytometry before and after co-culturing.</p><p><strong>Results: </strong>Epidermal stem cells and sweat gland cells were in line with their respective specific antigens .Before co-cultured, epidermal stem cells highly expressed β1 integrin (98.69 ± 0.67)％,hardly expressed CEA (6.20 ± 3.15)％.After co-cultured,β1 integrin expression levels were showed as knockdown group (19.30 ± 0.53) ％ ＜blank control group (65.77 ± 2.32)％ ＜ overexpress group (92.63 ± 10.97)％,and CEA expression levels as knockdown (95.43 ±2.36)％ ＞ blank control group (51.20 ±0.79)％ ＞ overexpress group (45.91 ±0.93)％.There had significant differences between those of each two groups.</p><p><strong>Conclusions: </strong>PRX-2 gene can inhibit the phenotypic change of Epidermal Stem Cells differentiating into Sweat Gland Cells and improve the ability to maintain their own specific antigens.</p>","PeriodicalId":69147,"journal":{"name":"中华整形外科杂志","volume":" ","pages":"37-42"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36366507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Recontruction of facial aesthetic subunit with kite flap after resection of benign tumor at supraorbital ridge].","authors":"Chi Zhang,&nbsp;Xiujun Tang,&nbsp;Dali Wang,&nbsp;Zairong Wei,&nbsp;Bo Wang,&nbsp;Jianping Qi,&nbsp;Hai Li,&nbsp;Chengliang Deng","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the recontruction of facial aesthetic subunit with kite flap after resection of benign tumor at supraorbital ridge.</p><p><strong>Methods: </strong>From June 2012 to September 2015,12 cases(8 male and 4 female, aged 34-68 years) with benign tumor at supraorbital ridge underwent tumor resection, following by reconstruction with kite flap. The tumor size ranged from 0.3 cm × 1.0 cm to 0.5 cm× 1.0 cm, and the defects size ranged from0.5 cm× 1.2 cmto0.8 cm×1.2 cm.The kite flaps were 0.6 cm × 1.2 cm to 1.0 cm × 1.5 cm.</p><p><strong>Results: </strong>All the 12 flaps survived completely with primary healing and no complication. The scar was inconspicious,which was hidden into brows. The brows showed good symmetric cosmetic effect.</p><p><strong>Conclusions: </strong>The kite flap has reliable blood supply and survival rate, which does not affect the brows symmetry. Aesthetic result can be achieved by Kite flap in the reconstruction of defect after resection of benign tumor at supraorbital ridge.</p>","PeriodicalId":69147,"journal":{"name":"中华整形外科杂志","volume":" ","pages":"12-5"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36366071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Thinning of the deep inferior epigastric artery perforator flap based on the vascular structure of the arterial perforator].","authors":"Bairong Fang,&nbsp;Yang Sun,&nbsp;Xiang Xiong,&nbsp;Jiyong He,&nbsp;Xiancheng WAng","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To explore flap thinning based on the study of the arterial structure and blood perfusion of the deep inferior epigastric artery perforator (DIEP) flap using computed tomography (CT) angiography.</p><p><strong>Methods: </strong>Clinical imaging study: Preoperative CT angiography was performed in 15 patients with DIEP flap reconstruction to investigate the vascular structure of arterial perforator. Cadaveric imaging study:10 abdominal specimens harvested from fresh cadavers were cannulated with trocar and injected with contrast medium in the deep inferior epigastric artery perforator. During the perfusion of the contrast medium in the flap,the flap was scanned by three-dimensional CT. The CT data was then sent to CT workstation and the images were processed and reformatted to study the vascular structure of arterial perforators and the blood perfusion.</p><p><strong>Results: </strong>75 artery perforators in clinical study and 40 artery perforators in cadaveric study were chosen and analyzed. The major deep inferior epigastric artery perforators run directly across the deep layer of adipose tissue without bifurcating beneath the Scarpa's fascia. Above the Scarpa's fascia, the artery perforators bifurcate and ultimately terminate in the subdermal vascular plexus. Blood perfusion mode: The subdermal vascular plexus served as the only pathway for blood perfusion between perforasomes. There are two different pathways for blood perfusion in the perforasome: the subdermal plexus and the existing vascular structure of perforator.</p><p><strong>Conclusions: </strong>Based on the vascular structure of arterial perforator and blood perfusion of the DIEP flap, thinning of the DIEP flap under the Scarpa's fascia is safe while thinning above the Scarpa's fascia should performed according to the blood supply zone of the DIEP flap.</p>","PeriodicalId":69147,"journal":{"name":"中华整形外科杂志","volume":" ","pages":"16-20"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36366072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The orbicularis muscle partial resection combined with orbital fat flap or orbicularis muscle flap graft for treatment of crow's feet in women].","authors":"Zhaowei Chen,&nbsp;Tong Liu,&nbsp;Jingxiang Shao,&nbsp;Tong Zhu,&nbsp;Huasheng Liu,&nbsp;Huanli Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To observe the effect of the outer orbicularis muscle partial resection combined with orbital fat flap or orbicularis muscle flap transfer to block orbicularis muscle for improvement of crow's feet.</p><p><strong>Methods: </strong>From October 2010 to May 2015,82 cases of females (aged from 27 to 54 years old) with crow's feet were treated with new method(n =41) and traditional method(control, n =41).The new method included partial resection and orbital fat flap or orbicularis muscle flap transfer to block orbicularis muscle. The traditional method was performed to lift the skin and orbicularis oculi muscle to improve the crow's feet. The operation time, the postoperative recovery time, eyes closing function and hematoma, nerve injury and other complications were recorded.1,3,6 and 12 months after operation, the effect was assessed by one cosmetic surgeon who is unkown the groups. Completely correction was assed as 5 points and no improvement or even worse as 0 point.12 months after operation, the patients satisfactory rate was recorded.</p><p><strong>Results: </strong>75 cases were followed up, including 39 in new method group and 36 in control group. The operative time and postoperative recovery time were (50 ± 5) min,(58 ± 4) min and (5 ±1) d,(6.0±1.5) d in the new method group and control group respectively (P＜0.05).The two groups both had good eyes closing function, no eyes closing fatigue or difficult or other serious complications such as hematoma, nerve injury. Visual analog scale were 3.2 ± 0.6,3.5 ± 0.5,4.2 ± 0.8,4.3 ±0.8 and 3.1 ±0.6,3.4 ±0.9,3.0 ±0.6,2.8 ±0.5 in the new method group and control group at 1,3,6,12 months after surgery respectively. Obviously, the effect in new method group was much better than that in control group after 6 and 12 months with statistical significance (P ＜ 0.05).12 months after surgery, the satisfaction surveys showed satisfactory in 33 cases; fairly satisfactory in 4 cases; dissatisfactory in 2 cases in new method group, and satisfactory in 10 cases; fairly satisfactory in 15 cases; dissatisfactory in 11 cases in the control group, showing significant difference between the 2 groups (P ＜0.05).</p><p><strong>Conclusions: </strong>The outer orbital orbicularis muscle partial resection combined with orbital fat flap or orbicularis muscle flap is reasonable and reliable to correct crow's feet with short recovery and less complication. It is a worthy new method for recommendation.</p>","PeriodicalId":69147,"journal":{"name":"中华整形外科杂志","volume":" ","pages":"4-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36365490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Anatomical basis of the flap based on the perforator of the deep palmar arch].","authors":"Peng Niu,&nbsp;Deqing Hu,&nbsp;Jian Lin,&nbsp;Tian Wang,&nbsp;Lei Huang,&nbsp;Xu Hong,&nbsp;Ruilin Qi,&nbsp;Heping Zheng","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the morphological characters of the dorsal perforators originated from the deep palmar arch,so as to provide anatomic basis for V-Y advanced perforator flap.</p><p><strong>Methods: </strong>The following contents were investigated in 30 aduh hand specimens perfused with red latex under surgical magnifier:① The origin, courses, branches and distribution of the dorsal perforators originated from the deep palmar arch. ②The characters of anastomosis among the dorsal perforators, the dorsal carpal and metacarpal arteries. Mimic operation was performed on another fresh specimens perfused with red latex.</p><p><strong>Results: </strong>There were three perforators originated from the deep palmar arch, which passed through the 2nd-4th dorsal interossei and then divided into an ascending branch and a descending branch at the dorsum of hand. Then the ascending branch anastomosed with the dorsal carpal artery, and the descending branch stretched to the 2nd-4th dorsal metacarpal arteries. The originating outer diameters of the 1st-3rd perforators were (1.1 ±0.2) mm,(0.9 ±0.3) mm and (0.7 ±0.1) mm respectively, and the length of the stems were (1.1 ±0.3) cm,(1.0 ±0.2)cm and (0.9 ±0.1) cm respectively.</p><p><strong>Conclusions: </strong>The V-Y advanced perforator flap with the dorsal perforator of the deep palmar arch as its vascular pedicle could be used to repair the dorsal carpal or dorsal metacarpal soft tissue defects.</p>","PeriodicalId":69147,"journal":{"name":"中华整形外科杂志","volume":" ","pages":"53-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36366077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}