Marine Biotechnology最新文献

{"title":"Tissue Mosaicism in Xenogenic Common Carp (Cyprinus carpio) Injected with Unsorted Gonadal Cells from Blue Catfish (Ictalurus furcatus)","authors":"Baofeng Su,&nbsp;Logan Bern,&nbsp;Kate B. Pottle,&nbsp;Darshika Udari Hettiarachchi,&nbsp;Mei Shang,&nbsp;Veronica Alston,&nbsp;Jacob Al-Armanazi,&nbsp;Misha Soman,&nbsp;Hamza Dilawar,&nbsp;Jinhai Wang,&nbsp;Ian A.E. Butts,&nbsp;Luke A. Roy,&nbsp;Anthony Moss,&nbsp;Rex A. Dunham","doi":"10.1007/s10126-025-10542-w","DOIUrl":"10.1007/s10126-025-10542-w","url":null,"abstract":"<div><p>Xenogenic individuals are sterilized hosts that are colonized by germ cells transplanted from a donor species and can subsequently produce donor-derived gametes. In our case, unsorted gonadal cells from a donor species injected near the genital ridge of a sterile surrogate should colonize only that region, eventually becoming donor gametes. Unsorted gonadal cells from blue catfish (<i>Ictalurus furcatus</i>) injected into triploid common carp (<i>Cyprinus carpio</i>) embryos and fry were detected by PCR assays predominantly in recipient gonads and, in a subset of individuals, occasionally in DNA extracts from pectoral fin, anal fin, or muscle tissue, resulting in mosaicism in these tissues (presence of donor DNA/cells). Recipients retained normal common carp morphology. Donor signal was not detected in other assayed tissues, including eyes, livers, intestines, and hearts. This is the first report of such aberrant, presumably gonadal stem cell migration and colonization outside the gonads in xenogenic fish. Individuals injected later in development had reduced or no mosaicism compared to those injected at early developmental stages. Catfish donor cells were detected in the gonad, muscle, anal fin, and pectoral fin of both diploid and triploid common carp hosts. The incidence of non-target tissues containing blue catfish DNA trended towards being higher in triploids than diploids, especially when mosaicism involved three tissues. These findings provide preliminary insights into donor unsorted gonadal cell migration, tissue-specific persistence, and developmental timing in reproductive biology. These PCR findings indicate tissue mosaicism but do not establish somatic differentiation.</p></div>","PeriodicalId":690,"journal":{"name":"Marine Biotechnology","volume":"27 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145720309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Comparative Genomics Analysis Provides Insights into Pregnancy Maintenance Mechanisms in the Ovoviviparous Teleost Black Rockfish (Sebastes schlegelii)","authors":"Xinlin Yang,&nbsp;Chong Zhang,&nbsp;Haishen Wen,&nbsp;Yun Li,&nbsp;Jianshuang Li,&nbsp;Bingyan Zheng,&nbsp;Chengpeng Zuo,&nbsp;Xin Qi","doi":"10.1007/s10126-025-10545-7","DOIUrl":"10.1007/s10126-025-10545-7","url":null,"abstract":"","PeriodicalId":690,"journal":{"name":"Marine Biotechnology","volume":"27 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145613156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcriptome Analysis Revealed the Copper Ion Uptake by Oocystis borgei from Offshore Polluted Water","authors":"Junyu Tang,&nbsp;Qizhao Liang,&nbsp;Rui Zhang,&nbsp;Xiaoping Huang","doi":"10.1007/s10126-025-10543-9","DOIUrl":"10.1007/s10126-025-10543-9","url":null,"abstract":"<div><p>Copper ion pollution poses a significant threat to marine ecosystems. Seaweeds exhibit potential for metal bioremediation through their inherent mechanisms of metal absorption and tolerance. However, the understanding of seaweed resistance to metal ions, particularly copper, continues to evolve, despite previous studies elucidating some underlying molecular mechanisms. This study delineates the transcriptomic adaptations of <i>Oocystis borgei</i> to copper exposure via RNA-seq, highlighting its remarkable bioremoval efficacy, consistently averages 82%. RNA sequencing revealed profound alterations in transcriptomic profiles, which were further examined through Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways analyses. This comprehensive examination identified key mechanisms facilitating copper absorption and enhanced tolerance in <i>Oocystis borgei</i>, including transporter activity, oxidation-reduction processes, photosynthesis, and glutathione metabolism. Overall, this analysis provides essential insights into the molecular mechanisms driving seaweed adaptive responses to copper-induced stress, laying the groundwork for future studies on their bioremediative capabilities.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":690,"journal":{"name":"Marine Biotechnology","volume":"27 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145613098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Natural Perkinsus Olseni Infection Abundance on the Lipid Metabolism in the Gills of Manila Clam (Ruditapes philippinarum)","authors":"Haoyi Jiang,&nbsp;Yuxiang Wang,&nbsp;Shengli Fu,&nbsp;Jie Lu,&nbsp;Tuo Yao,&nbsp;Jingyue Zhang,&nbsp;Zhaozhong Zhang,&nbsp;Yaotong Hao,&nbsp;Zhifu Liang,&nbsp;Lingtong Ye","doi":"10.1007/s10126-025-10544-8","DOIUrl":"10.1007/s10126-025-10544-8","url":null,"abstract":"<div><p><i>Perkinsus olseni</i> is a highly pathogenic protozoan parasite affecting mollusks worldwide, posing a significant threat to Manila clam (<i>Ruditapes philippinarum</i>) aquaculture. This study investigated the impact of natural <i>P. olseni</i> infection abundance on the gill lipid metabolism of clams collected from Dandong City, Liaoning Province. The parasite species was identified via Polymerase Chain Reaction (PCR), while infection prevalence, abundance, and infection grade classification were assessed using Ray’s Fluid Thioglycolate Medium (RFTM) culture. Lipid metabolomics analysis was performed to compare lipid profiles among uninfected (Neg), lightly infected (L), and moderately infected (M) clam gills. Results confirmed the presence of <i>P. olseni</i> with an overall prevalence of 91%. The infection abundance was significantly higher in the gills and digestive gland than in the mantle and siphon tissues. Lipidomic analysis of 18 samples (6 biological replicates per Neg, L, and M group) using a Liquid Chromatography-Mass Spectrometry (LC-MS) platform identified 1,561 metabolites, with significant differences observed across infection groups. 28 differential lipid metabolites were common to both the L and M groups when compared to the Neg group. KEGG pathway enrichment and correlation network analysis highlighted two key metabolites: diacylglycerol (DG) (16:0/18:2) and triacylglycerol (TG) (18:0/18:1/18:2). These metabolites were associated with 13 pathways, including T cell receptor signaling, fat digestion and absorption, and regulation of lipolysis in adipocytes. These findings elucidate tissue-specific infection patterns and reveal lipid metabolic reprogramming in clam gills in response to <i>P. olseni</i>, providing insights into host-parasite interactions and potential metabolic biomarkers for perkinsosis.</p></div>","PeriodicalId":690,"journal":{"name":"Marine Biotechnology","volume":"27 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145601558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stimulating the Growth of Chlorella Microalgae Using Ultrasound","authors":"Dmitry S. Dvoretsky,&nbsp;Mikhail S. Temnov,&nbsp;Viktoria O. Milenina,&nbsp;Alexandra K. Bryankina,&nbsp;Anastasia A. Paramonova,&nbsp;Kirill I. Meronyuk","doi":"10.1007/s10126-025-10540-y","DOIUrl":"10.1007/s10126-025-10540-y","url":null,"abstract":"<div><p>The study investigated the effect of ultrasonic radiation on the growth of <i>Chlorella</i> microalgae cells and the accumulation of intracellular metabolites (intracellular water-soluble proteins, lipids) in them. The results of the study showed that daily ultrasonic radiation (72 J/ml) with a power of 300 W for 60 s had a significant positive effect on the growth rate of microalgae. Increasing the ultrasound power from 20 W (4.8 J/mL) to 300 W (72 J/mL) resulted in a 1.3-fold increase in cell concentration in suspension and 1.4-fold increase in biomass concentration after 24 days of cultivation. The positive effect of ultrasound treatment on the process of periodic cultivation of microalgae is attributed to the acceleration of metabolism due to the increase in temperature of the suspension and the destruction of extracellular phenolic metabolites that inhibit the nitrate-anion transport system. In addition, ultrasound has a positive effect on the accumulation of intracellular metabolites in the biomass (the concentration of intracellular water-soluble proteins and total lipids became 1.4-fold and 2-fold higher, respectively, compared to the control). The research aims to increase the efficiency of the cultivation stage and may have practical significance for microalgae producers and researchers involved in the development of new methods to improve the production and obtain valuable substances from microalgae.</p></div>","PeriodicalId":690,"journal":{"name":"Marine Biotechnology","volume":"27 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145601616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Marine-Derived Polysaccharides Through In Vitro and Zebrafish In Vivo Assays: Initial Trends of A Novel Approach to Drug Screening","authors":"Sofía Latorre-Redoli,&nbsp;Piedad Valverde-Guillén,&nbsp;Jorge García-Márquez,&nbsp;Félix L. Figueroa,&nbsp;Roberto Abdala-Díaz,&nbsp;Manuel Marí-Beffa","doi":"10.1007/s10126-025-10531-z","DOIUrl":"10.1007/s10126-025-10531-z","url":null,"abstract":"<div><p>The sulfated polysaccharides derived from marine species have attracted attention for their nutraceutical and pharmaceutical potential. Initially examined in cell culture, many labs have further tested their activity in in vivo rodent assays. Zebrafish embryos have been recently proposed as an alternative model species to test anti-inflammatory, fungicidal, immunomodulatory, antioxidant, antitumour, or toxicity effects with significant success. In this article, we systematically review by PRISMA strategy the assays that use zebrafish to evaluate potential nutraceutical and pharmaceutical applications of polysaccharides from more than 30 marine algal species. Effects against cancer, inflammation, and oxidative stress or over regeneration capacity, immunomodulation, and photoprotection in zebrafish are here compared. From this review, some polysaccharides appear as safe antitumour compounds (e.g. neutral <i>S. skottsbergii</i>–derived fraction over G-361 melanoma) while others show significant toxicity to embryos. The current bibliography shows a clear trend to use in parallel zebrafish larvae and in vitro assays to test the effects of polysaccharide fractions recovered from a variety of bioprocesses from different marine algae–derived biomass. Its potential application in the pharmacology and nutraceutical industry is discussed.</p></div>","PeriodicalId":690,"journal":{"name":"Marine Biotechnology","volume":"27 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145585772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glycine-rich Kunitz-type Serine Protease Inhibitor (HcGrKuSPI) Prevents Extracellular Degradation of Matrix Proteins during Shell Formation in Hyriopsis Cumingii","authors":"Can Jin,&nbsp;Jiayi Zhang,&nbsp;Xiaoyang Tan,&nbsp;Fangmengjie Wei,&nbsp;Zhiyi Bai,&nbsp;Wen Luo","doi":"10.1007/s10126-025-10537-7","DOIUrl":"10.1007/s10126-025-10537-7","url":null,"abstract":"<div><p>Mollusk shell formation is a delicate and comprehensive physiological process that relies on the precise deposition of crystals under the control of shell matrix proteins. However, the underlying protective mechanisms governing this process remain largely unknown. Herein, a novel shell matrix protein gene was identified from the freshwater mussel, <i>Hyriopsis cumingii</i>. The predicted protein is characterized by a high glycine content and two Kunitz-type SPI domains, designated as <i>Hc</i>GrKuSPI. The <i>Hc</i>GrKuSPI gene was highly expressed in the outer epithelial of the mantle edge and mantle pallial. Immunostaining in situ analysis revealed the presence of <i>Hc</i>GrKuSPI in the thick inter-prism matrix of the prismatic layer and the organic membrane of the nacreous layer. The expression of <i>Hc</i>GrKuSPI in the pearl sac significantly increased during the ordered deposition of pearl nacre tablets. The resultant recombinant protein, SUMO-<i>Hc</i>GrKuSPI, exhibited a strong affinity for aragonite and calcite and was involved in the morphological modification of calcite crystals in vitro. These results indicate that <i>Hc</i>GrKuSPI is involved in organic framework construction and crystal morphological modification during the prismatic and nacreous layers formation. Furthermore, the expression of <i>Hc</i>GrKuSPI in the mantle significantly increased following bacterial infection within the extrapallial fluid, and SUMO-<i>Hc</i>GrKuSPI exhibited a strong inhibitory effect against bacterial growth and trypsin activity. Antibody injection in vivo led to severe damage to the thick inter-column framework of the prismatic layer and morphological deformities of nacre tablets. These findings indicate that <i>Hc</i>GrKuSPI exhibits excellent protease inhibitory and antibacterial activities, providing a matrix protection system to ensure the smoothness of shell and pearl formation. Overall, these results enhance our understanding of the protective mechanisms involved in mollusk biomineralization.</p></div>","PeriodicalId":690,"journal":{"name":"Marine Biotechnology","volume":"27 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145547544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current State of Fish Reference Genome and Pangenome: Methodologies, Sampling Strategies, Quality Assessment and Future Perspectives to Aquaculture Breeding","authors":"Zhanjiang Liu,&nbsp;Dongya Gao","doi":"10.1007/s10126-025-10535-9","DOIUrl":"10.1007/s10126-025-10535-9","url":null,"abstract":"<div><p>Genome research has dominated life sciences research in the last two decades. Of approximately 11,000 sequenced vertebrate genomes, genomes of teleost fish represent about 30%, with reference genome sequences available for most aquaculture fish species. While such progress has accelerated progress in aquaculture genetics research and breeding, it is clear that understanding of full genomic variations among aquaculture species is lacking. This is largely because of the way reference genomic sequences were produced, with a single or just a few genomes being sequenced. In addition, haplotype variations and their representation in the species or population are unknown. This hinders understanding of genomic basis of phenotypic variations relevant to performance and production traits such as growth rates, feed conversion efficiency, disease resistance, stress responses, processing yields, and reproductive traits, among other traits, especially so with strain-specific performance traits. The pangenome refers to a whole collection of genomic sequences found in the entire species or population rather than in a single individual, as represented in reference genomes. Pangenome includes the core genome sequence that are shared in all individuals, and variable or dispensable genome sequence found in a subset of individuals, representing intraspecies genomic variations. In this review, we present the current state of reference genomes and reference pangenomes, compare the advantages and disadvantages of various methods in producing pangenomes, propose the concept of pangenome plus (pangenome⁺) to include genomes of related species with which interspecific hybrids can be made to introgress the beneficial genes. Revealing full genomic variations, determination of genomic variations relevant to performance traits, and combining beneficial genes and alleles into aquaculture breeds are three most important steps for the application of genome-based technologies to aquaculture breeding. To accomplish these three steps is challenging but offers unprecedented opportunities for aquaculture.</p></div>","PeriodicalId":690,"journal":{"name":"Marine Biotechnology","volume":"27 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145538219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genome-wide Identification and Expression Profiling Indicate the Segon Gene Family Diversity and their Possible Role in Shell Formation in Oysters","authors":"Xiangjie Kong,&nbsp;Sheng Liu,&nbsp;Li Tan,&nbsp;Youli Liu,&nbsp;Zhihua Lin,&nbsp;Qinggang Xue","doi":"10.1007/s10126-025-10536-8","DOIUrl":"10.1007/s10126-025-10536-8","url":null,"abstract":"<p>Bivalves dominate global marine aquaculture, with shell biomineralization mediated by hemocytes and specialized proteins. Segon, the second-most abundant plasma protein in oysters, contains high calcium content and is hypothesized to participate in shell formation via calcium transportation. However, its gene family distribution and functional dynamics remain unexplored. This study aimed to systematically identify <i>segon</i> gene family, analyze their structural and evolutionary features, and elucidate expression patterns for developmental stages and shell damage response. Twelve <i>segon</i> genes were identified exclusively in family Ostreidae, with no gene found in other studied mollusks. All Segon proteins were predicted to be acidic (pI 4.98 ~ 6.07), hydrophilic, and localized to the extracellular space with a high Asp/Glu content indicating predicted calcium-binding capacity. Analysis of aligned <i>segon</i> sequences revealed that in <i>Crassostrea virginica</i>, <i>segon</i> and <i>dominin</i> did not form a fusion gene, whereas in all other species, <i>segon</i> sequences encompassed the <i>dominin</i> sequence. In silico predicted tertiary structures revealed conserved β-sheets and α-helices. <i>segon</i> transcript abundance was nearly undetectable in early larvae but sharply increased in spat-stage across oyster species, coinciding with the transition from aragonite to calcite shell polymorphs. The <i>segon</i> gene family is unique to Ostreidae and likely evolved through gene fusion events. Its spatiotemporal expression and structural features suggest that Segon possibly plays a vital role in calcium transport, offering novel targets for understanding oyster biomineralization and aquaculture enhancement.</p>","PeriodicalId":690,"journal":{"name":"Marine Biotechnology","volume":"27 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145538300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Transcription Factor-based Framework for Monitoring Stress Status in Oysters: Applications in Conservation and Restoration","authors":"Shen-Tong Wang,&nbsp;Li Li,&nbsp;Qi Yang,&nbsp;Wei Wang,&nbsp;Ming-Kun Liu,&nbsp;Xin-Xing Wang,&nbsp;Yu Wang,&nbsp;Guo-Fan Zhang","doi":"10.1007/s10126-025-10539-5","DOIUrl":"10.1007/s10126-025-10539-5","url":null,"abstract":"<div><p>Developing effective molecular indicators to monitor stress status of coastal species is a top priority due to the impacts of climate change. However, the complexity of stress responses, which are regulated by multiple genes, limits the effectiveness of single-gene approaches in accurately reflecting stress status. Transcription factors (TFs) are promising candidates for comprehensively assessing stress responses, as they regulate numerous stress-responsive genes. In this study, we present a framework for identifying TF indicators that reflect the stress status of Pacific oysters (<i>Crassostrea gigas</i>). Specifically, oysters were exposed to high, medium, and low tide conditions to assess the physiological responses of oysters to tidal-induced stress. Enrichment analysis of differentially accessible chromatin peaks derived from assay for transposase-accessible chromatin sequencing (ATAC-seq) identified several key TFs. Among these, <i>CCCTC-binding factor</i> (<i>Cg</i>-<i>CTCF</i>) and <i>MYB proto-oncogene A</i> (<i>Cg-MYBA</i>) were significantly upregulated under tidal-induced stress and occupied critical positions in regulatory networks, as indicated by RNA-seq. RNA interference experiments confirmed that both genes contribute to enhancing survival under heat stress, a major stressor affecting oysters. Additionally, field experiments demonstrated significant upregulation of these genes under natural stress conditions, suggesting their potential as indicators for oyster reef management. To our knowledge, this is the first study on the coastal invertebrate to combine ATAC/RNA-seq with in vivo TF knockdown and field validation to propose TFs as practical stress indicators. We advocate for the broad application of our framework to explore TFs as molecular indicators of health status in marine organisms, thereby enabling informed strategies for conservation management.</p></div>","PeriodicalId":690,"journal":{"name":"Marine Biotechnology","volume":"27 6","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10126-025-10539-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145538257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}