2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)最新文献_第9页

A Microfluidic Device Platform Reconstructing Lung Pattern for Cancer Immunotherapy Applications 一种用于肿瘤免疫治疗的肺形态重建微流控装置平台

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495673

Yu-Chen Chen, Han-Jung Liao, Jean-An Chich, Pin-Tzu Lai, Yi-Ying Liang, Kang-Yun Lee, Wei-Lun Sun, S. Ho, Yu-Shiuan Wang, Wan-Chen Huang, Wei-Chiao Chang, Sung-Yang Wei, Cheng-Hsien Liu

{"title":"A Microfluidic Device Platform Reconstructing Lung Pattern for Cancer Immunotherapy Applications","authors":"Yu-Chen Chen, Han-Jung Liao, Jean-An Chich, Pin-Tzu Lai, Yi-Ying Liang, Kang-Yun Lee, Wei-Lun Sun, S. Ho, Yu-Shiuan Wang, Wan-Chen Huang, Wei-Chiao Chang, Sung-Yang Wei, Cheng-Hsien Liu","doi":"10.1109/Transducers50396.2021.9495673","DOIUrl":"https://doi.org/10.1109/Transducers50396.2021.9495673","url":null,"abstract":"Cancer is one of the leading causes of death globally. To simulate a similar environment of human tissue is the difficulty in cancer research. The development of 3D culture model is used to imitate the environment to provide a potential research strategy. Matrigel is the most commonly used material for 3D culture models. However, it is derived from murine tumors, unsuitable for clinical applications. In this study, the methacrylated gelatin (GelMA) was blended with type I collagen as a biomaterial in our microfluidic device. We further optimized the device design; it can perform entirely experimental functions without requiring complicated parts such as pumps and valves. On this microfluidic platform, the biocompatible hydrogel and cells could be patterned via liquid dielectrophoresis (LDEP) and dielectrophoretic force (DEP). The experimental results demonstrated that the human lung cancer cells were patterned via both DEP/LDEP and light-curing hydrogel with low cell mortality. The patterned cells' mortality rate is less than 5% after 24 hr of cultivation. Our results suggest the potential of this device for future clinical cancer study applications. Furthermore, we also expect to achieve bionic tumors and explore the interaction between 3D cell models and drugs.","PeriodicalId":6814,"journal":{"name":"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)","volume":"169 1","pages":"479-482"},"PeriodicalIF":0.0,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85077854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Compact Acoustic Particle Velocity Gradient Sensor Based on MEMS Hot-Wire Sensor Chips 基于MEMS热线传感器芯片的小型声粒子速度梯度传感器

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495574

Lingmeng Yang, Zhezheng Zhu, Wenhan Chang, Fanrui Meng, Chengchen Gao, Y. Hao, Zhenchuan Yang

引用次数: 2

Development of a Thermo-Computing Platform 热计算平台的开发

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495663

V. Shirmohammadli, B. Bahreyni

{"title":"Development of a Thermo-Computing Platform","authors":"V. Shirmohammadli, B. Bahreyni","doi":"10.1109/Transducers50396.2021.9495663","DOIUrl":"https://doi.org/10.1109/Transducers50396.2021.9495663","url":null,"abstract":"There is an increasing demand for the recognition of context from sensor data. This is presently achieved through running complicated statistical signal processing algorithms with significant computing and memory requirements. In order to reduce the complexity and power requirements, unconventional computing platforms are being considered, which rely on the responses of the materials or devices instead of digitizing information and processing them. Herein, for the first time to the best of our knowledge, we propose a thermo-computing platform, which can shift much of the complex computations to the sensors. The proposed platform employs an entirely passive network of thermistors for processing temporal data. We present results that confirm the capability of the thermo-computer in processing data. A thermo-computer was then used for processing benchmark data, and its results are compared against algorithmic programming. The proposed platform, in addition to its use as a thermal computer, can lay the foundation for the development of cognizant sensor that utilize thermistor-like devices, such as MOX multi-gas sensors.","PeriodicalId":6814,"journal":{"name":"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)","volume":"141 1","pages":"1307-1310"},"PeriodicalIF":0.0,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89216987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biofunctional and Self-Contractable Silk-Based Sensing Threads 生物功能和自收缩丝绸传感线

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495408

Yating Xie, Keyin Liu, T. Tao

引用次数: 0

Heterogeneous LiNbO3/Si Direct Bonding for Wavelength-Dependent Mid-Infrared Imaging 非均相LiNbO3/Si直接键合用于波长相关的中红外成像

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495511

Jikai Xu, Zhihao Ren, Xinmiao Liu, Cheng Xu, Chenxi Wang, Yanhong Tian, Chengkuo Lee

{"title":"Heterogeneous LiNbO3/Si Direct Bonding for Wavelength-Dependent Mid-Infrared Imaging","authors":"Jikai Xu, Zhihao Ren, Xinmiao Liu, Cheng Xu, Chenxi Wang, Yanhong Tian, Chengkuo Lee","doi":"10.1109/Transducers50396.2021.9495511","DOIUrl":"https://doi.org/10.1109/Transducers50396.2021.9495511","url":null,"abstract":"Lithium niobate (LiNbO3) is one of the most important multifunctional materials, which possesses excellent electro-optic and piezoelectric properties, as well as high transmittance in the mid-infrared (mid-IR) wavelength range. In this work, we developed a wet sequential plasma activated method for the heterogeneous direct bonding of single-crystal LiNbO3 and Si with a nanometer-scale (∼6.4 nm) interface. Both surface and interface characterizations are used for the exploration of the bonding mechanism. For the first time, atomic structures of the LiNbO3/Si direct bonding interface have been disclosed. Leveraging this direct bonding method, we creatively integrate the metasurface into the LiNbO3-based nanofluidics for wavelength-dependent imaging. Because of the accurate nanogap control between the nanoantenna and metal reflector, the quadrupole resonance can be well excited. Therefore, the mid-IR imaging with ultrahigh contrast has been achieved in the wavelength of $2.68 mu mathrm{m}, 3.16 mu mathrm{m}$, and $3.61 mumathrm{m}$. Moreover, since the hot spots are completely exposed in the nanochamber, which can be filled with various types of liquids. More images can be designed and presented based on the light-matter interaction and changes of refractive index. Therefore, this hybrid LiNbO3-based nanofluidics has great potential in the applications of switchable optical devices and information encryption.","PeriodicalId":6814,"journal":{"name":"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)","volume":"120 1","pages":"585-588"},"PeriodicalIF":0.0,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87793171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intersecting Book Inspired High-Power-Density Electret/Triboelectric Multilayered Power Generator with Flexible Interdigital Electrodes 具有柔性数字间电极的高功率密度驻极体/摩擦电多层发电机

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495628

Hao Huang, Zhe Zhao, K. Tao, Jin Wu, Bowen Ji, W. Yuan, Honglong Chang

{"title":"Intersecting Book Inspired High-Power-Density Electret/Triboelectric Multilayered Power Generator with Flexible Interdigital Electrodes","authors":"Hao Huang, Zhe Zhao, K. Tao, Jin Wu, Bowen Ji, W. Yuan, Honglong Chang","doi":"10.1109/Transducers50396.2021.9495628","DOIUrl":"https://doi.org/10.1109/Transducers50396.2021.9495628","url":null,"abstract":"Inspired by the classic friction phenomenon in life, a multi-layer interdigital Electret/Triboelectric Multilayered Power Generator (ET-MPG) that imitates the friction of book pages is designed. Its production is based on a flexible substrate and has special properties that other rigid devices do not have. For example, a very small positive pressure can increase its output performance by 80%, and the final peak power density can reach 0.18W/m2. Through exploration experiments, it is known that the number of output peaks of the interdigital electrode has a corresponding relationship with the number of figures, and the output performance can be multiplied. When the sliding rate is 1m/s, the highest peak voltage reaches 30 V, the average output power of a single layer reaches 10 µW, and the power density can reach 54 mW/m2 in the preliminary results. In addition, by exploring the influencing factors of the friction between the intersecting books, we can understand the large amount of energy contained in this multi-layer flexible structure. The peak energy density of a single page reaches 2.3 J/m2. In addition, the electret generator not only has a high-performance output, but also because it uses all flexible materials, its wearing comfort is unmatched by other rigid devices. This is of great significance to the energy supply of wearable devices and the energy collection on the surface of the human body.","PeriodicalId":6814,"journal":{"name":"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)","volume":"7 1","pages":"936-939"},"PeriodicalIF":0.0,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87945736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biomimic Antibacterial Sensing Silk Bio-Patch 仿生抗菌传感丝生物贴片

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495518

Zhiheng Gao, T. Tao, Keyin Liu

引用次数: 0

Particle Size Determination in Impedance Flow Cytometry Using Measured Opacity 采用测量不透明度的阻抗流式细胞术测定颗粒大小

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495740

Douwe S de Bruijn, K. F. Jorissen, W. Olthuis, A. van den Berg

引用次数: 1

Characterization of Smart Hydrogel-Based Ultrasound Resonators for Implantable Sensing Applications 用于植入式传感应用的智能水凝胶超声谐振器的表征

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495729

Navid Farhoudi, P. Kairy, J. Magda, F. Solzbacher, C. Reiche

{"title":"Characterization of Smart Hydrogel-Based Ultrasound Resonators for Implantable Sensing Applications","authors":"Navid Farhoudi, P. Kairy, J. Magda, F. Solzbacher, C. Reiche","doi":"10.1109/Transducers50396.2021.9495729","DOIUrl":"https://doi.org/10.1109/Transducers50396.2021.9495729","url":null,"abstract":"Many biomedical sensing concepts for continuous monitoring of analytes rely on implanting electronic components inside the body to operate, which raises issues about long-term biocompatibility. In recent reports, an implantable sensing modality was reported in which ultrasound absorption in smart hydrogel resonators at a particular probing frequency is used to track the changes in ionic strength and glucose concentration of an analyte solution. This sensing concept allows the implanted component to be free from electronics, with corresponding possible advantages with respect to biocompatibility and lifetime of the device. However, an unsuitable probing frequency can undermine the received signal's quality from the implants or even entirely cause a signal loss. Here we present our work on creating an ultrasound characterization system and using it to determine optimum probing frequencies for the hydrogel resonator structures within a given frequency window. Furthermore, we demonstrate that the signal amplitude depends on the probing frequency's location relative to the frequency response peaks at a fixed dynamic range for swelling of smart hydrogels.","PeriodicalId":6814,"journal":{"name":"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)","volume":"47 1","pages":"839-842"},"PeriodicalIF":0.0,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87018235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single-Chip Integration of CMOS Compatible Mems Temperature/Humidity and Highly Sensitive Flow Sensors for Human Thermal Comfort Sensing Application CMOS兼容Mems温度/湿度和高灵敏度流量传感器的单芯片集成，用于人体热舒适传感应用

2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495565

Izhar, Wei-Qing Xu, Hadi Tavakkoli, Jose Cabot, Xu Zhao, Mingzheng Duan, Yi-Kuen Lee

{"title":"Single-Chip Integration of CMOS Compatible Mems Temperature/Humidity and Highly Sensitive Flow Sensors for Human Thermal Comfort Sensing Application","authors":"Izhar, Wei-Qing Xu, Hadi Tavakkoli, Jose Cabot, Xu Zhao, Mingzheng Duan, Yi-Kuen Lee","doi":"10.1109/Transducers50396.2021.9495565","DOIUrl":"https://doi.org/10.1109/Transducers50396.2021.9495565","url":null,"abstract":"In this work, we report a single-chip integration of CMOS compatible MEMS temperature, humidity, and highly sensitive flow sensor for the application of human thermal comfort (HTC) sensing. The present multi-sensors chip (MSC) comes up with a couple of merits. Firstly, it utilizes a low-cost 3-mask fabrication process to fabricate temperature, humidity, and flow sensors on a single chip with a proper packaging layer (parylene C) that acts as both packaging (for temperature & flow sensors) and a humidity sensing layer. Secondly, a fully released thermoresistive calorimetric flow (TCF) sensor with dual pairs of detectors is fabricated to achieve high sensitivity. The fabricated (flow, humidity, and temperature) sensors were characterized under different air velocities, humidity, and temperature levels, respectively. The measurement results indicated a maximum sensitivity of 312 mV/ms−1 for the developed TCF sensor with dual detectors design which is almost doubled compared to conventional single pair of detectors design. Furthermore, the humidity sensor achieved an average sensitivity of 7.83 fF/%RH, whereas the temperature sensor shows a resistance change of $5.78Omega/^{circ}mathrm{C}$ and TCR of $1.43 times 10^{-3}/^{circ} mathrm{C}$. The experimental results indicated that our MSC is promising for the HTC sensing application for smart buildings in the era of Internet of Things (IoT).","PeriodicalId":6814,"journal":{"name":"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)","volume":"42 1","pages":"1219-1222"},"PeriodicalIF":0.0,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87208656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4