世界危重病急救学杂志(英文版)最新文献

{"title":"Delta shock index predicts injury severity, interventions, and outcomes in trauma patients: A 10-year retrospective observational study.","authors":"Mohammad Asim, Ayman El-Menyar, Khalid Ahmed, Mushreq Al-Ani, Saji Mathradikkal, Abubaker Alaieb, Abdel Aziz Hammo, Ibrahim Taha, Ahmad Kloub, Hassan Al-Thani","doi":"10.5492/wjccm.v13.i4.99587","DOIUrl":"10.5492/wjccm.v13.i4.99587","url":null,"abstract":"<p><strong>Background: </strong>Most trauma occurs among young male subjects in Qatar. We examined the predictive values of the delta shock index (DSI), defined as the change in the shock index (SI) value from the scene to the initial reading in the emergency unit (<i>i.e.</i>, subtracting the calculated SI at admission from SI at the scene), at a Level 1 trauma center.</p><p><strong>Aim: </strong>To explore whether high DSI is associated with severe injuries, more interventions, and worse outcomes [<i>i.e.</i>, blood transfusion, exploratory laparotomy, ventilator-associated pneumonia, hospital length of stay (HLOS), and in-hospital mortality] in trauma patients.</p><p><strong>Methods: </strong>A retrospective analysis was conducted after data were extracted from the National Trauma Registry between 2011 and 2021. Patients were grouped based on DSI as low (≤ 0.1) or high (> 0.1). Data were analyzed and compared using <i>χ</i> ² and Student's <i>t</i>-tests. Correlations between DSI and injury severity score (ISS), revised trauma score (RTS), abbreviated injury scale (AIS), Glasgow coma scale (GCS), trauma score-ISS (TRISS), HLOS, and number of transfused blood units (NTBU), were assessed using correlation coefficient analysis. The diagnostic testing accuracy for predicting mortality was determined using the validity measures of the DSI. Logistic regression analysis was performed to identify predictors of mortality.</p><p><strong>Results: </strong>This analysis included 13212 patients with a mean age of 33 ± 14 years, and 24% had a high DSI. Males accounted for 91% of the study population. The trauma activation level was higher in patients with a high DSI (38% <i>vs</i> 15%, <i>P</i> = 0.001). DSI correlated with RTS (<i>r</i> = -0.30), TRISS (<i>r</i> = -0.30), NTBU (<i>r</i> = 0.20), GCS (<i>r</i> = -0.24), ISS (<i>r</i> = 0.22), and HLOS (<i>r</i> = 0.14) (<i>P</i> = 0.001 for all). High DSI was associated with significantly higher rates of intubation, laparotomy, ventilator-associated pneumonia, massive transfusion activation, and mortality than low DSI. For mortality prediction, a high DSI had better specificity, negative predictive value, and negative likelihood ratio (77%, 99%, and 0.49%, respectively). After adjusting for age, emergency medical services time, GCS score, and ISS, multivariable regression analysis showed that DSI was an independent predictor of mortality (odds ratio = 1.9; 95% confidence interval: 1.35-2.76).</p><p><strong>Conclusion: </strong>In addition to sex-biased observations, almost one-quarter of the study cohort had a higher DSI and were mostly young. High DSI correlated significantly with the other injury severity scores, which require more time and imaging to be ready to use. Therefore, DSI is a practical, simple bedside tool for triaging and prognosis in young patients with trauma.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"13 4","pages":"99587"},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspectives on non-emergent neonatal intensive care unit to pediatric intensive care unit care transfers in the United States.","authors":"Phillip D Cohen, Renee D Boss, David C Stockwell, Meghan Bernier, Joseph M Collaco, Sapna R Kudchadkar","doi":"10.5492/wjccm.v13.i4.97145","DOIUrl":"10.5492/wjccm.v13.i4.97145","url":null,"abstract":"<p><strong>Background: </strong>There is a substantial population of long-stay patients who non-emergently transfer directly from the neonatal intensive care unit (NICU) to the pediatric intensive care unit (PICU) without an interim discharge home. These infants are often medically complex and have higher mortality relative to NICU or PICU-only admissions. Given an absence of data surrounding practice patterns for non-emergent NICU to PICU transfers, we hypothesized that we would encounter a broad spectrum of current practices and a high proportion of dissatisfaction with current processes.</p><p><strong>Aim: </strong>To characterize non-emergent NICU to PICU transfer practices across the United States and query PICU providers' evaluations of their effectiveness.</p><p><strong>Methods: </strong>A cross-sectional survey was drafted, piloted, and sent to one physician representative from each of 115 PICUs across the United States based on membership in the PARK-PICU research consortium and membership in the Children's Hospital Association. The survey was administered <i>via</i> internet (REDCap). Analysis was performed using STATA, primarily consisting of descriptive statistics, though logistic regressions were run examining the relationship between specific transfer steps, hospital characteristics, and effectiveness of transfer.</p><p><strong>Results: </strong>One PICU attending from each of 81 institutions in the United States completed the survey (overall 70% response rate). Over half (52%) indicated their hospital transfers patients without using set clinical criteria, and only 33% indicated that their hospital has a standardized protocol to facilitate non-emergent transfer. Fewer than half of respondents reported that their institution's non-emergent NICU to PICU transfer practices were effective for clinicians (47%) or patient families (38%). Respondents evaluated their centers' transfers as less effective when they lacked any transfer criteria (<i>P</i> = 0.027) or set transfer protocols (<i>P</i> = 0.007). Respondents overwhelmingly agreed that having set clinical criteria and standardized protocols for non-emergent transfer were important to the patient-family experience and patient safety.</p><p><strong>Conclusion: </strong>Most hospitals lacked any clinical criteria or protocols for non-emergent NICU to PICU transfers. More positive perceptions of transfer effectiveness were found among those with set criteria and/or transfer protocols.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"13 4","pages":"97145"},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Driving pressure: A useful tool for reducing postoperative pulmonary complications.","authors":"Domenico Posa, Fabio Sbaraglia, Giuliano Ferrone, Marco Rossi","doi":"10.5492/wjccm.v13.i3.96214","DOIUrl":"https://doi.org/10.5492/wjccm.v13.i3.96214","url":null,"abstract":"<p><p>The operating room is a unique environment where surgery exposes patients to non-physiological changes that can compromise lung mechanics. Therefore, raising clinicians' awareness of the potential risk of ventilator-induced lung injury (VILI) is mandatory. Driving pressure is a useful tool for reducing lung complications in patients with acute respiratory distress syndrome and those undergoing elective surgery. Driving pressure has been most extensively studied in the context of single-lung ventilation during thoracic surgery. However, the awareness of association of VILI risk and patient positioning (prone, beach-chair, park-bench) and type of surgery must be raised.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"13 3","pages":"96214"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why do thoracic epidurals fail? A literature review on thoracic epidural failure and catheter confirmation.","authors":"Kamal Kumar, Fuhazia Horner, Mohamed Aly, Gopakumar S Nair, Cheng Lin","doi":"10.5492/wjccm.v13.i3.94157","DOIUrl":"https://doi.org/10.5492/wjccm.v13.i3.94157","url":null,"abstract":"<p><p>Thoracic epidural anesthesia (TEA) has been the gold standard of perioperative analgesia in various abdominal and thoracic surgeries. However, misplaced or displaced catheters, along with other factors such as technical challenges, equipment failure, and anatomic variation, lead to a high incidence of unsatisfactory analgesia. This article aims to assess the different sources of TEA failure and strategies to validate the location of thoracic epidural catheters. A literature search of PubMed, Medline, Science Direct, and Google Scholar was done. The search results were limited to randomized controlled trials. Literature suggests techniques such as electrophysiological stimulation, epidural waveform monitoring, and x-ray epidurography for identifying thoracic epidural placement, but there is no one particular superior confirmation method; clinicians are advised to select techniques that are practical and suitable for their patients and practice environment to maximize success.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"13 3","pages":"94157"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reimagining critical care: Trends and shifts in 21^st century medicine.","authors":"Sai Doppalapudi, Bilal Khan, Muhammad Adrish","doi":"10.5492/wjccm.v13.i3.94020","DOIUrl":"https://doi.org/10.5492/wjccm.v13.i3.94020","url":null,"abstract":"<p><p>Critical care medicine has undergone significant evaluation in the 21^st century, primarily driven by advancements in technology, changes in healthcare delivery, and a deeper understanding of disease processes. Advancements in technology have revolutionized patient monitoring, diagnosis, and treatment in the critical care setting. From minimally invasive procedures to advances imaging techniques, clinicians now have access to a wide array of tools to assess and manage critically ill patients more effectively. In this editorial we comment on the review article published by Padte S <i>et al</i> wherein they concisely describe the latest developments in critical care medicine.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"13 3","pages":"94020"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of different intravenous bolus rates on fluid and electrolyte balance and mortality in critically ill patients.","authors":"Mutaz I Othman, Emad M Mustafa, Moayad Alfayoumi, Mohamad Y Khatib, Abdulqadir J Nashwan","doi":"10.5492/wjccm.v13.i3.95781","DOIUrl":"https://doi.org/10.5492/wjccm.v13.i3.95781","url":null,"abstract":"<p><p>The effect of intravenous bolus rates on patient outcomes is a complex and crucial aspect of critical care. Fluid challenges are commonly used in critically ill patients to manage their hemodynamic status, but there is limited information available on the specifics of when, how much, and at what rate fluids should be administered during these challenges. The aim of this review is to thoroughly examine the relationship between intravenous bolus rates, fluid-electrolyte balance, and mortality and to analyze key research findings and methodologies to understand these complex dynamics better. Fluid challenges are commonly employed in managing hemodynamic status in this population, yet there is limited information on the optimal timing, volume, and rate of fluid administration. Utilizing a narrative review approach, the analysis identified nine relevant studies that investigate these variables. The findings underscore the importance of a precise and individualized approach in clinical settings, highlighting the need to tailor intravenous bolus rates to each patient's specific needs to maximize outcomes. This review provides valuable insights that can inform and optimize clinical practices in critical care, emphasizing the necessity of meticulous and exact strategies in fluid administration.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"13 3","pages":"95781"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of COVID-19 infection in patients on antihypertensives: A cross-sectional study.","authors":"Sakthivadivel Varatharajan, Gopal K Bohra, Pradeep K Bhatia, Satyendra Khichar, Mahadev Meena, Naveenraj Palanisamy, Archana Gaur, Mahendra K Garg","doi":"10.5492/wjccm.v13.i3.96882","DOIUrl":"https://doi.org/10.5492/wjccm.v13.i3.96882","url":null,"abstract":"<p><strong>Background: </strong>Patients with coronavirus disease 2019 (COVID-19) infection frequently have hypertension as a co-morbidity, which is linked to adverse outcomes. Antihypertensives may affect the outcome of COVID-19 infection.</p><p><strong>Aim: </strong>To assess the effects of antihypertensive agents on the outcomes of COVID-19 infection.</p><p><strong>Methods: </strong>A total of 260 patients were included, and their demographic data and clinical profile were documented. The patients were categorized into nonhypertensive, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (ACEI/ARB), calcium channel blocker (CCB), a combination of ACEI/ARB and CCB, and beta-blocker groups. Biochemical, hematological, and inflammatory markers were measured. The severity of infection, intensive care unit (ICU) intervention, and outcome were recorded.</p><p><strong>Results: </strong>The mean age of patients was approximately 60-years-old in all groups, except the nonhypertensive group. Men were predominant in all groups. Fever was the most common presenting symptom. Acute respiratory distress syndrome was the most common complication, and was mostly found in the CCB group. Critical cases, ICU intervention, and mortality were also higher in the CCB group. Multivariable logistic regression analysis revealed that age, duration of antihypertensive therapy, erythrocyte sedimentation rate, high-sensitivity C-reactive protein, and interleukin 6 were significantly associated with mortality. The duration of antihypertensive therapy exhibited a sensitivity of 70.8% and specificity of 55.7%, with a cut-off value of 4.5 years and an area under the curve of 0.670 (0.574-0.767; 95% confidence interval) for COVID-19 outcome.</p><p><strong>Conclusion: </strong>The type of antihypertensive medication has no impact on the clinical sequence or mortality of patients with COVID-19 infection. However, the duration of antihypertensive therapy is associated with poor outcomes.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"13 3","pages":"96882"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traumatic brain injury and variants of shock index.","authors":"Sai Doppalapudi, Muhammad Adrish","doi":"10.5492/wjccm.v13.i3.93478","DOIUrl":"https://doi.org/10.5492/wjccm.v13.i3.93478","url":null,"abstract":"<p><p>Traumatic Brain Injury is a major cause of death and long-term disability. The early identification of patients at high risk of mortality is important for both management and prognosis. Although many modified scoring systems have been developed for improving the prediction accuracy in patients with trauma, few studies have focused on prediction accuracy and application in patients with traumatic brain injury. The shock index (SI) which was first introduced in the 1960s has shown to strongly correlate degree of circulatory shock with increasing SI. In this editorial we comment on a publication by Carteri <i>et al</i> wherein they perform a retrospective analysis studying the predictive potential of SI and its variants in populations with severe traumatic brain injury.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"13 3","pages":"93478"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low T3 <i>vs</i> low T3T4 euthyroid sick syndrome in septic shock patients: A prospective observational cohort study.","authors":"Mirza Kovacevic, Visnja Nesek-Adam, Semir Klokic, Ekrema Mujaric","doi":"10.5492/wjccm.v13.i3.96132","DOIUrl":"https://doi.org/10.5492/wjccm.v13.i3.96132","url":null,"abstract":"<p><strong>Background: </strong>Both phases of euthyroid sick syndrome (ESS) are associated with worse prognosis in septic shock patients. Although there are still no indications for supplementation therapy, there is no evidence that both phases (initial and prolonged) are adaptive or that only prolonged is maladaptive and requires supplementation.</p><p><strong>Aim: </strong>To analyze clinical, hemodynamic and laboratory differences in two groups of septic shock patients with ESS.</p><p><strong>Methods: </strong>A total of 47 septic shock patients with ESS were divided according to values of their thyroid hormones into low T3 and low T3T4 groups. The analysis included demographic data, mortality scores, intensive care unit stay, mechanical ventilation length and 28-day survival and laboratory with hemodynamics.</p><p><strong>Results: </strong>The Simplified Acute Physiology Score II score (<i>P</i> = 0.029), dobutamine (<i>P</i> = 0.003) and epinephrine requirement (<i>P</i> = 0.000) and the incidence of renal failure and multiple organ failure (MOF) (<i>P</i> = 0.000) were significantly higher for the low T3T4. Hypoalbuminemia (<i>P</i> = 0.047), neutrophilia (<i>P</i> = 0.038), lymphopenia (<i>P</i> = 0.013) and lactatemia (<i>P</i> = 0.013) were more pronounced on T2 for the low T3T4 group compared to the low T3 group. Diastolic blood pressure at T0 (<i>P</i> = 0.017) and T1 (<i>P</i> = 0.007), as well as mean arterial pressure at T0 (<i>P</i> = 0.037) and T2 (<i>P</i> = 0.033) was higher for the low T3 group.</p><p><strong>Conclusion: </strong>The low T3T4 population is associated with higher frequency of renal insufficiency and MOF, with worse laboratory and hemodynamic parameters. These findings suggest potentially maladaptive changes in the chronic phase of septic shock.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"13 3","pages":"96132"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early clinical outcomes of two regimens of prophylactic antibiotics in cardiac surgical patients with delayed sternal closure.","authors":"Mahmoud Ismail Allam Eissa, Rasha Kaddoura, Danial Hassan, Cornelia S Carr, Samy Hanoura, Yasser Shouman, Abdulwahid Almulla, Amr Salah Omar","doi":"10.5492/wjccm.v13.i3.92658","DOIUrl":"https://doi.org/10.5492/wjccm.v13.i3.92658","url":null,"abstract":"<p><strong>Background: </strong>Delayed sternal closure (DSC) can be a lifesaving approach for certain patients who have undergone cardiac surgery. The value of the type of prophylactic antibiotics in DSC is still debatable.</p><p><strong>Aim: </strong>To investigate clinical outcomes of different prophylactic antibiotic regimens in patients who had DSC after cardiac surgery.</p><p><strong>Methods: </strong>This was a retrospective observational single-center study. Fifty-three consecutive patients who underwent cardiac surgery and had an indication for DSC were included. Patients were subjected to two regimens of antibiotics: Narrow-spectrum and broad-spectrum regimens.</p><p><strong>Results: </strong>The main outcome measures were length of hospital and intensive care unit (ICU) stay, duration of mechanical ventilation, and mortality. Of the 53 patients, 12 (22.6%) received narrow-spectrum antibiotics, and 41 (77.4%) received broad-spectrum antibiotics. The mean age was 59.0 ± 12.1 years, without significant differences between the groups. The mean duration of antibiotic use was significantly longer in the broad-spectrum than the narrow-spectrum group (11.9 ± 8.7 <i>vs</i> 3.4 ± 2.0 d , <i>P</i> < 0.001). The median duration of open chest was 3.0 (2.0-5.0) d for all patients, with no difference between groups (<i>P</i> = 0.146). The median duration of mechanical ventilation was significantly longer in the broad-spectrum group [60.0 (Δ interquartile range (IQR) 170.0) h <i>vs</i> 50.0 (ΔIQR 113.0) h, <i>P</i> = 0.047]. Similarly, the median length of stay for both ICU and hospital were significantly longer in the broad-spectrum group [7.5 (ΔIQR 10.0) d <i>vs</i> 5.0 (ΔIQR 5.0) d, <i>P</i> = 0.008] and [27.0 (ΔIQR 30.0) d <i>vs</i> 19.0 (ΔIQR 21.0) d, <i>P</i> = 0.031]. Five (9.8%) patients were readmitted to the ICU and 18 (34.6%) patients died without a difference between groups.</p><p><strong>Conclusion: </strong>Prophylactic broad-spectrum antibiotics did not improve clinical outcomes in patients with DSC post-cardiac surgery but was associated with longer ventilation duration, length of ICU and hospital stays <i>vs</i> narrow-spectrum antibiotics.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":"13 3","pages":"92658"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}