世界危重病急救学杂志(英文版)最新文献

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Antimicrobial and synergistic effects of lemongrass and geranium essential oils against Streptococcus mutans, Staphylococcus aureus, and Candida spp. 柠檬草和天竺葵精油对变异链球菌、金黄色葡萄球菌和白色念珠菌的抗菌和协同作用
世界危重病急救学杂志(英文版) Pub Date : 2024-09-09 DOI: 10.5492/wjccm.v13.i3.92531
Patrícia Michelle Nagai de Lima, Thaís Cristine Pereira, Lara Steffany de Carvalho, Letícia Ferreira Dos Santos, Carlos Eduardo Rocha Oliveira, Lucas de Paula Ramos, Maria Cristina Marcucci, Amjad Abu Hasna, Luciane Dias de Oliveira
{"title":"Antimicrobial and synergistic effects of lemongrass and geranium essential oils against <i>Streptococcus mutans</i>, <i>Staphylococcus aureus</i>, and <i>Candida</i> spp.","authors":"Patrícia Michelle Nagai de Lima, Thaís Cristine Pereira, Lara Steffany de Carvalho, Letícia Ferreira Dos Santos, Carlos Eduardo Rocha Oliveira, Lucas de Paula Ramos, Maria Cristina Marcucci, Amjad Abu Hasna, Luciane Dias de Oliveira","doi":"10.5492/wjccm.v13.i3.92531","DOIUrl":"https://doi.org/10.5492/wjccm.v13.i3.92531","url":null,"abstract":"<p><strong>Background: </strong>The oral cavity harbors more than 700 species of bacteria, which play crucial roles in the development of various oral diseases including caries, endodontic infection, periodontal infection, and diverse oral diseases.</p><p><strong>Aim: </strong>To investigate the antimicrobial action of <i>Cymbopogon Schoenanthus</i> and <i>Pelargonium graveolens</i> essential oils against <i>Streptococcus mutans, Staphylococcus aureus, Candida albicans, Ca. dubliniensis</i>, and <i>Ca. krusei</i>.</p><p><strong>Methods: </strong>Minimum microbicidal concentration was determined following Clinical and Laboratory Standards Institute documents. The synergistic antimicrobial activity was evaluated using the Broth microdilution checkerboard method, and the antibiofilm activity was evaluated with the 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide assay. Data were analyzed by one-way analysis of variance followed by the Tukey post-hoc test (<i>P</i> ≤ 0.05).</p><p><strong>Results: </strong><i>C. schoenanthus</i> and <i>P. graveolens</i> essential oils were as effective as 0.12% chlorhexidine against <i>S. mutans</i> and <i>St. aureus</i> monotypic biofilms after 24 h. After 24 h <i>P. graveolens</i> essential oil at 0.25% was more effective than the nystatin group, and <i>C. schoenanthus</i> essential oil at 0.25% was as effective as the nystatin group.</p><p><strong>Conclusion: </strong><i>C. schoenanthus</i> and <i>P. graveolens</i> essential oils are effective against <i>S. mutans, St. aureus, Ca. albicans, Ca. dubliniensis</i>, and <i>Ca. krusei</i> at different concentrations after 5 min and 24 h.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis and management of severe pulmonary and extrapulmonary tuberculosis in critically ill patients: A mini review for clinicians. 重症患者严重肺结核和肺外结核病的诊断与管理:临床医生小综述。
世界危重病急救学杂志(英文版) Pub Date : 2024-06-09 DOI: 10.5492/wjccm.v13.i2.91435
Dominic Ti Ming Tan, Kay Choong See
{"title":"Diagnosis and management of severe pulmonary and extrapulmonary tuberculosis in critically ill patients: A mini review for clinicians.","authors":"Dominic Ti Ming Tan, Kay Choong See","doi":"10.5492/wjccm.v13.i2.91435","DOIUrl":"10.5492/wjccm.v13.i2.91435","url":null,"abstract":"<p><p>Among critically ill patients, severe pulmonary and extrapulmonary tuberculosis has high morbidity and mortality. Yet, it is a diagnostic challenge given its nonspecific clinical symptoms and signs in early stages of the disease. In addition, management of severe pulmonary and extrapulmonary tuberculosis is complicated given the high risk of drug-drug interactions, drug-disease interactions, and adverse drug reactions. To help clinicians acquire an up-to-date approach to severe tuberculosis, this paper will provide a narrative review of contemporary diagnosis and management of severe pulmonary and extrapulmonary tuberculosis in critically ill patients.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Future of neurocritical care: Integrating neurophysics, multimodal monitoring, and machine learning. 神经重症监护的未来:整合神经物理学、多模态监测和机器学习。
世界危重病急救学杂志(英文版) Pub Date : 2024-06-09 DOI: 10.5492/wjccm.v13.i2.91397
Bahadar S Srichawla
{"title":"Future of neurocritical care: Integrating neurophysics, multimodal monitoring, and machine learning.","authors":"Bahadar S Srichawla","doi":"10.5492/wjccm.v13.i2.91397","DOIUrl":"10.5492/wjccm.v13.i2.91397","url":null,"abstract":"<p><p>Multimodal monitoring (MMM) in the intensive care unit (ICU) has become increasingly sophisticated with the integration of neurophysical principles. However, the challenge remains to select and interpret the most appropriate combination of neuromonitoring modalities to optimize patient outcomes. This manuscript reviewed current neuromonitoring tools, focusing on intracranial pressure, cerebral electrical activity, metabolism, and invasive and noninvasive autoregulation monitoring. In addition, the integration of advanced machine learning and data science tools within the ICU were discussed. Invasive monitoring includes analysis of intracranial pressure waveforms, jugular venous oximetry, monitoring of brain tissue oxygenation, thermal diffusion flowmetry, electrocorticography, depth electroencephalography, and cerebral microdialysis. Noninvasive measures include transcranial Doppler, tympanic membrane displacement, near-infrared spectroscopy, optic nerve sheath diameter, positron emission tomography, and systemic hemodynamic monitoring including heart rate variability analysis. The neurophysical basis and clinical relevance of each method within the ICU setting were examined. Machine learning algorithms have shown promise by helping to analyze and interpret data in real time from continuous MMM tools, helping clinicians make more accurate and timely decisions. These algorithms can integrate diverse data streams to generate predictive models for patient outcomes and optimize treatment strategies. MMM, grounded in neurophysics, offers a more nuanced understanding of cerebral physiology and disease in the ICU. Although each modality has its strengths and limitations, its integrated use, especially in combination with machine learning algorithms, can offer invaluable information for individualized patient care.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Point-of-care ultrasonography spotlight: Could venous excess ultrasound serve as a shared language for internists and intensivists? 护理点超声聚焦:静脉过度超声检查能否成为内科医生和重症监护医生的共同语言?
世界危重病急救学杂志(英文版) Pub Date : 2024-06-09 DOI: 10.5492/wjccm.v13.i2.93206
Anosh Aslam Khan, Hasham Saeed, Ibtehaj Ul Haque, Ayman Iqbal, Doantrang Du, Abhilash Koratala
{"title":"Point-of-care ultrasonography spotlight: Could venous excess ultrasound serve as a shared language for internists and intensivists?","authors":"Anosh Aslam Khan, Hasham Saeed, Ibtehaj Ul Haque, Ayman Iqbal, Doantrang Du, Abhilash Koratala","doi":"10.5492/wjccm.v13.i2.93206","DOIUrl":"10.5492/wjccm.v13.i2.93206","url":null,"abstract":"<p><p>Point-of-care ultrasonography (POCUS), particularly venous excess ultrasound (VExUS) is emerging as a valuable bedside tool to gain real-time hemodynamic insights. This modality, derived from hepatic vein, portal vein, and intrarenal vessel Doppler patterns, offers a scoring system for dynamic venous congestion assessment. Such an assessment can be crucial in effective management of patients with heart failure exacerbation. It facilitates diagnosis, quantification of congestion, prognostication, and monitoring the efficacy of decongestive therapy. As such, it can effectively help to manage cardiorenal syndromes in various clinical settings. Extended or eVExUS explores additional veins, potentially broadening its applications. While VExUS demonstrates promising outcomes, challenges persist, particularly in cases involving renal and liver parenchymal disease, arrhythmias, and situations of pressure and volume overload overlap. Proficiency in utilizing spectral Doppler is pivotal for clinicians to effectively employ this tool. Hence, the integration of POCUS, especially advanced applications like VExUS, into routine clinical practice necessitates enhanced training across medical specialties.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ten misconceptions regarding decision-making in critical care. 关于重症监护决策的十大误解。
世界危重病急救学杂志(英文版) Pub Date : 2024-06-09 DOI: 10.5492/wjccm.v13.i2.89644
Tara Ramaswamy, Jamie L Sparling, Marvin G Chang, Edward A Bittner
{"title":"Ten misconceptions regarding decision-making in critical care.","authors":"Tara Ramaswamy, Jamie L Sparling, Marvin G Chang, Edward A Bittner","doi":"10.5492/wjccm.v13.i2.89644","DOIUrl":"10.5492/wjccm.v13.i2.89644","url":null,"abstract":"<p><p>Diagnostic errors are prevalent in critical care practice and are associated with patient harm and costs for providers and the healthcare system. Patient complexity, illness severity, and the urgency in initiating proper treatment all contribute to decision-making errors. Clinician-related factors such as fatigue, cognitive overload, and inexperience further interfere with effective decision-making. Cognitive science has provided insight into the clinical decision-making process that can be used to reduce error. This evidence-based review discusses ten common misconceptions regarding critical care decision-making. By understanding how practitioners make clinical decisions and examining how errors occur, strategies may be developed and implemented to decrease errors in Decision-making and improve patient outcomes.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critical care specialists, the missing link in organ procurement for transplantation. 重症监护专家是器官移植中缺失的一环。
世界危重病急救学杂志(英文版) Pub Date : 2024-06-09 DOI: 10.5492/wjccm.v13.i2.90274
Francisca Del Rocio Gonzalez Cohens, Fernando M Gonzalez
{"title":"Critical care specialists, the missing link in organ procurement for transplantation.","authors":"Francisca Del Rocio Gonzalez Cohens, Fernando M Gonzalez","doi":"10.5492/wjccm.v13.i2.90274","DOIUrl":"10.5492/wjccm.v13.i2.90274","url":null,"abstract":"<p><p>The procurement process for organ donation begins with the identification of potential organ donors in emergency or critical care units (CCU), followed by their clinical evaluation, diagnostic procedures, and therapeutic interventions, mostly conducted in CCUs. It concludes with the request for organ donation and, if accepted, the retrieval of organs. Despite most interventions occurring in detection units, there has been a neglect of the strategic role played by critical care specialists (CCS) in managing and caring for brain-dead or near-brain-death patients. Questions arise: Are they willing to undertake this responsibility? Do they fully comprehend the nature of organ procurement? Are they aware of the specific interventions required to maintain possible organ donors in optimal physiological condition? Our objective is to examine the role of CCS in organ procurement and propose ways to enhance it, ultimately aiming to increase and enhance organ donation rates.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Driving pressure decoded: Precision strategies in adult respiratory distress syndrome management. 驱动压力解码:成人呼吸窘迫综合征管理的精准策略。
世界危重病急救学杂志(英文版) Pub Date : 2024-06-09 DOI: 10.5492/wjccm.v13.i2.92441
Muhammad Adrish, Sai Doppalapudi, Dmitry Lvovsky
{"title":"Driving pressure decoded: Precision strategies in adult respiratory distress syndrome management.","authors":"Muhammad Adrish, Sai Doppalapudi, Dmitry Lvovsky","doi":"10.5492/wjccm.v13.i2.92441","DOIUrl":"10.5492/wjccm.v13.i2.92441","url":null,"abstract":"<p><p>Mechanical ventilation (MV) is an important strategy for improving the survival of patients with respiratory failure. However, MV is associated with aggravation of lung injury, with ventilator-induced lung injury (VILI) becoming a major concern. Thus, ventilation protection strategies have been developed to minimize complications from MV, with the goal of relieving excessive breathing workload, improving gas exchange, and minimizing VILI. By opting for lower tidal volumes, clinicians seek to strike a balance between providing adequate ventilation to support gas exchange and preventing overdistension of the alveoli, which can contribute to lung injury. Additionally, other factors play a role in optimizing lung protection during MV, including adequate positive end-expiratory pressure levels, to maintain alveolar recruitment and prevent atelectasis as well as careful consideration of plateau pressures to avoid excessive stress on the lung parenchyma.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Major liver resections, perioperative issues and posthepatectomy liver failure: A comprehensive update for the anesthesiologist. 肝脏大部切除术、围手术期问题和肝切除术后肝功能衰竭:麻醉医师的全面更新。
世界危重病急救学杂志(英文版) Pub Date : 2024-06-09 DOI: 10.5492/wjccm.v13.i2.92751
Andrea De Gasperi, Laura Petrò, Ombretta Amici, Ilenia Scaffidi, Pietro Molinari, Caterina Barbaglio, Eva Cibelli, Beatrice Penzo, Elena Roselli, Andrea Brunetti, Maxim Neganov, Alessandro Giacomoni, Paolo Aseni, Elena Guffanti
{"title":"Major liver resections, perioperative issues and posthepatectomy liver failure: A comprehensive update for the anesthesiologist.","authors":"Andrea De Gasperi, Laura Petrò, Ombretta Amici, Ilenia Scaffidi, Pietro Molinari, Caterina Barbaglio, Eva Cibelli, Beatrice Penzo, Elena Roselli, Andrea Brunetti, Maxim Neganov, Alessandro Giacomoni, Paolo Aseni, Elena Guffanti","doi":"10.5492/wjccm.v13.i2.92751","DOIUrl":"10.5492/wjccm.v13.i2.92751","url":null,"abstract":"<p><p>Significant advances in surgical techniques and relevant medium- and long-term outcomes over the past two decades have led to a substantial expansion in the indications for major liver resections. To support these outstanding results and to reduce perioperative complications, anesthesiologists must address and master key perioperative issues (preoperative assessment, proactive intraoperative anesthesia strategies, and implementation of the Enhanced Recovery After Surgery approach). Intensive care unit monitoring immediately following liver surgery remains a subject of active and often unresolved debate. Among postoperative complications, posthepatectomy liver failure (PHLF) occurs in different grades of severity (A-C) and frequency (9%-30%), and it is the main cause of 90-d postoperative mortality. PHLF, recently redefined with pragmatic clinical criteria and perioperative scores, can be predicted, prevented, or anticipated. This review highlights: (1) The systemic consequences of surgical manipulations anesthesiologists must respond to or prevent, to positively impact PHLF (a proactive approach); and (2) the maximal intensive treatment of PHLF, including artificial options, mainly based, so far, on Acute Liver Failure treatment(s), to buy time waiting for the recovery of the native liver or, when appropriate and in very selected cases, toward liver transplant. Such a clinical context requires a strong commitment to surgeons, anesthesiologists, and intensivists to work together, for a fruitful collaboration in a mandatory clinical continuum.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serotonin syndrome controversies: A need for consensus. 血清素综合征的争议:需要达成共识。
世界危重病急救学杂志(英文版) Pub Date : 2024-06-09 DOI: 10.5492/wjccm.v13.i2.94707
Sanjay Prakash, Chetsi S Shah, Anurag Prakash
{"title":"Serotonin syndrome controversies: A need for consensus.","authors":"Sanjay Prakash, Chetsi S Shah, Anurag Prakash","doi":"10.5492/wjccm.v13.i2.94707","DOIUrl":"10.5492/wjccm.v13.i2.94707","url":null,"abstract":"<p><p>Serotonin syndrome (SS) is a drug-induced clinical syndrome resulting from increased serotonergic activity in the central nervous system. Although more than seven decades have passed since the first description of SS, it is still an enigma in terms of terminology, clinical features, etiology, pathophysiology, diagnostic criteria, and therapeutic measures. The majority of SS cases have previously been reported by toxicology or psychiatry centers, particularly in people with mental illness. However, serotonergic medications are used for a variety of conditions other than mental illness. Serotonergic properties have been discovered in several new drugs, including over-the-counter medications. These days, cases are reported in non-toxicology centers, such as perioperative settings, neurology clinics, cardiology settings, gynecology settings, and pediatric clinics. Overdoses or poisonings of serotonergic agents constituted the majority of the cases observed in toxicology or psychiatry centers. Overdose or poisoning of serotonergic drugs is uncommon in other clinical settings. Patients may develop SS at therapeutic dosages. Moreover, these patients may continue to use serotonergic medications even if they develop mild to moderate SS due to several reasons. Thus, the clinical presentation (onset, severity, and clinical features) in such instances may not exactly match what toxicologists or psychiatrists observe in their respective settings. They produce considerable diversity in many aspects of SS. However, other experts discount these new developments in SS. Since SS is a potentially lethal illness, consensus is required on several concerns related to SS.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Community-acquired pneumonia: The importance of the early detection of drug-resistant organisms. 社区获得性肺炎:早期发现耐药菌的重要性。
世界危重病急救学杂志(英文版) Pub Date : 2024-06-09 DOI: 10.5492/wjccm.v13.i2.91314
Sai Doppalapudi, Muhammad Adrish
{"title":"Community-acquired pneumonia: The importance of the early detection of drug-resistant organisms.","authors":"Sai Doppalapudi, Muhammad Adrish","doi":"10.5492/wjccm.v13.i2.91314","DOIUrl":"10.5492/wjccm.v13.i2.91314","url":null,"abstract":"<p><p>Pneumonia is a disease associated with significant healthcare burden with over 1.5 million hospitalizations annually and is the eighth leading cause of death in the United States. While community-acquired pneumonia (CAP) is generally considered an acute time-limited illness, it is associated with high long-term mortality, with nearly one-third of patients requiring hospitalization dying within one year. An increasing trend of detecting multidrug-resistant (MDR) organisms causing CAP has been observed, especially in the Western world. In this editorial, we discuss about a publication by Jatteppanavar <i>et al</i> which reported that a case of a MDR organism was the culprit in developing pneumonia, bacteremia, and infective endocarditis that led to the patient's death. The early detection of these resistant organisms helps improve patient outcomes. Significant advances have been made in the biotechnological and research space, but preventive measures, diagnostic techniques, and treatment strategies need to be developed.</p>","PeriodicalId":66959,"journal":{"name":"世界危重病急救学杂志(英文版)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11155498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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