Chinese Journal of Plastic and Reconstructive Surgery最新文献

{"title":"Trends and key contributors in peripheral nerve regeneration research: A bibliometric study","authors":"Siddig Ibrahim Abdelwahab ,&nbsp;Abdullah Farasani ,&nbsp;Zenat A. Khired ,&nbsp;Ahmad Assiri ,&nbsp;Abdelkhalig Hussein Elhilu ,&nbsp;Waseem Hassan","doi":"10.1016/j.cjprs.2025.05.002","DOIUrl":"10.1016/j.cjprs.2025.05.002","url":null,"abstract":"<div><h3>Background</h3><div>Peripheral nerve regeneration is a critical research area with significant implications for neurology, neurosurgery, and regenerative medicine. A bibliometric analysis was conducted to provide a structured overview of research trends, intellectual impact, and evolving themes in peripheral nerve regeneration. This study aimed to identify the most influential research articles on peripheral nerve regeneration; analyze keyword trends, thematic evolution, and co-word structures; assess the contributions of top authors, universities, and countries; and examine collaboration networks and research dynamics.</div></div><div><h3>Methods</h3><div>A systematic bibliometric approach was employed using two search strategies. The first strategy involved searching within the title, abstract, and keyword fields, yielding 15 ​317 papers, whereas the second strategy was restricted to searching titles only, retrieving 3 531 papers. From these, the 100 most cited papers were selected for analysis. A thematic analysis was conducted using co-word clustering. The leading contributors were ranked according to the number of publications, citations, h-index, g-index, and m-index.</div></div><div><h3>Results</h3><div>The bibliometric analysis provided several key insights. Keyword analysis using bi- and tri-gram techniques revealed the dominant research themes within the field. The top contributors, including authors, universities, and countries, were ranked based on their productivity and citation impact. Collaboration networks were mapped at the author, institutional, and country levels, highlighting key partnerships and global research interactions. Thematic analysis classified research into seven major domains: neural regeneration and repair; cellular and molecular biology; biomaterials and tissue engineering; experimental studies and statistical analyses; functional and therapeutic aspects; neuropathic pain and peripheral nerve disorders; and Schwann cell and cellular responses. Additionally, the ten most influential papers were reviewed in detail to understand their contributions to the field.</div></div><div><h3>Conclusion</h3><div>This study provides a comprehensive and structured overview of peripheral nerve regeneration research. These findings offer valuable insights into the intellectual foundation of the field by identifying key contributors, research trends, and collaboration patterns. The results serve as a guide for future research, helping researchers to navigate the evolving landscape of peripheral nerve regeneration.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"7 2","pages":"Pages 111-121"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144471321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From solid to fluid: The possible role of tissue fluidity in mechanical stretch-induced tissue expansion","authors":"Shengzhou Shan,&nbsp;Xusong Luo","doi":"10.1016/j.cjprs.2024.11.008","DOIUrl":"10.1016/j.cjprs.2024.11.008","url":null,"abstract":"<div><div>Tissue expansion is a widely utilized technique in plastic and reconstructive surgery; however, the biological mechanisms underlying the skin response remain poorly understood. We propose that tissue fluidity, the transition of tissue from a solid-like state to a fluid-like state, plays a pivotal role in enabling the reorganization of the epidermal structure and cellular spatial order, which is essential for effective tissue expansion. Drawing parallels between fluidity in materials science and biological systems, we suggest that the fluid-like behavior in the skin may be critical for mechanical adaptability. Understanding the influence of tissue fluidity may open pathways for modulating this process, potentially enhancing tissue expansion efficiency, reducing procedural duration, and improving clinical outcomes. This perspective highlights the importance of investigating the biological dynamics of tissue fluidity and exploring the potential for targeted manipulation of fluidity-related pathways to optimize tissue expansion. Such advancements could profoundly affect regenerative and reconstructive surgical practices.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"7 1","pages":"Pages 56-58"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel therapeutic approaches with poly-L-lactic acid for treating gluteal skin laxity in male patients","authors":"Antony de Paula Barbosa,&nbsp;Alan Cristian Marinho Ferreira,&nbsp;Aline Castellar Duarte,&nbsp;Rafaella Vilela da Silva","doi":"10.1016/j.cjprs.2024.11.006","DOIUrl":"10.1016/j.cjprs.2024.11.006","url":null,"abstract":"<div><div>Poly-L-lactic acid (PLLA) has become a popular treatment for body skin laxity, especially in female patients; however, research on its use in male patients remains limited, particularly in addressing changes in the gluteal region due to aging. This case report investigates the efficacy of PLLA in treating skin laxity in the gluteal area of three male patients aged 36, 41, and 50 years who were treated at the Antony Barbosa Institute between May 2023 and June 2024. The Male Gluteal Contour Method™: C-Tech Collagen Boost was employed using a C-shaped injection technique with an 18G × 70 mm cannula. Patients underwent four sessions of PLLA injections, reconstituted with bacteriostatic sterile water and lidocaine, at 4–6-week intervals. Improvements in the gluteal contour and skin laxity were noted in all patients, with increased collagen production contributing to enhanced muscle definition and firmness. Minimal side effects such as mild bruising, swelling, and tenderness were reported, and no nodules were observed. This study highlights the importance of tailored treatment plans that cater to the specific needs of middle-age and older men. The C-shaped injection technique allowed for an even distribution of the biostimulator while respecting male anatomy. PLLA is a promising nonsurgical solution for improving male gluteal contour and skin quality, although further research with larger groups is warranted to establish more definitive guidelines for its use in male gluteal augmentation.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"7 1","pages":"Pages 23-29"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of the Chinese version of the Clinician-reported submental fat rating scale","authors":"Yuming Chong ,&nbsp;Yilin Li ,&nbsp;Xiaojun Wang ,&nbsp;Nanze Yu ,&nbsp;Jiuzuo Huang ,&nbsp;Hairu Cao ,&nbsp;Wenyun Ting ,&nbsp;Xiao Long","doi":"10.1016/j.cjprs.2024.12.003","DOIUrl":"10.1016/j.cjprs.2024.12.003","url":null,"abstract":"<div><h3>Background</h3><div>Excess submental fat (SMF) is a common facial aesthetic concern, and assessment scales play a crucial role in its evaluation. Existing SMF scales are based on Caucasian populations, although genetic background significantly influences SMF distribution. Therefore, this study aimed to develop and validate a 5-point Chinese version of the Clinician-Reported Submental Fat Rating Scale (CR-SMFRS).</div></div><div><h3>Methods</h3><div>The study included 150 volunteers, and captured photographs from the frontal, oblique, and lateral views were combined for each participant. A 5-point scale with descriptive criteria was primarily designed. Internal validation involved three experienced plastic surgeons, while external validation was conducted on 50 live volunteers by six additional raters. Intra- and inter-rater reliability were assessed.</div></div><div><h3>Results</h3><div>A 5-point grading system with descriptive criteria was developed and validated as the Chinese CR-SMFRS. Internal validation demonstrated a good intra- and inter-rater consistency. During external validation, intraclass correlation coefficient values for each rater exceeded 0.850, indicating high intra-rater consistency. Moreover, the inter-rater reliability showed good consistency.</div></div><div><h3>Conclusion</h3><div>The Chinese version of the SMF rating scale is a reliable tool for clinical use.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"7 1","pages":"Pages 1-4"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of 3D-printed rehabilitation aids for hypertrophic scars","authors":"Danyang Zhao ,&nbsp;Jia Xu ,&nbsp;Xin Li,&nbsp;Jiajun Fan,&nbsp;Tianyi Shen,&nbsp;Zijing Du,&nbsp;Yi Cao,&nbsp;Hao Jiang,&nbsp;Dong Han","doi":"10.1016/j.cjprs.2024.12.005","DOIUrl":"10.1016/j.cjprs.2024.12.005","url":null,"abstract":"<div><div>Hypertrophic scars (HS) are fibrotic proliferative diseases that develop after deep skin injuries caused by trauma, burns, and surgery. Traditional treatment methods include both surgical and nonsurgical therapies. Early intervention and combination therapy tailored to the individual needs of the patients are crucial for achieving optimal results. Three-dimensional (3D) printing technology, a rapid prototyping technique, is increasingly being applied in the medical field. The customization and precise functionality of 3D printing technology are particularly important for the rehabilitation of HS. This review provides an overview of HS and the role of 3D printing technology in medical applications, analyses the application of 3D-printed rehabilitation aids for HS, and discusses the use of 3D printing technology to improve HS treatment outcomes, thereby providing clinical guidance for effective HS rehabilitation.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"7 1","pages":"Pages 49-55"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined therapy of a case of multiple venous malformation with FLT4 gene mutation","authors":"Yang Yang ,&nbsp;Ningyuan Gao ,&nbsp;Ming Ren ,&nbsp;Lu Wang ,&nbsp;Zixu Gao ,&nbsp;Rongkui Luo ,&nbsp;Chuanyuan Wei ,&nbsp;Jianying Gu","doi":"10.1016/j.cjprs.2024.11.004","DOIUrl":"10.1016/j.cjprs.2024.11.004","url":null,"abstract":"<div><div>As the study of vascular anomalies progresses, it is imperative for plastic surgeons to individualize their in-depth research and practice to develop more effective and personalized treatment plans. Recent advancements in genome sequencing technology have highlighted the importance of vascular endothelial growth factor (VEGF) and its receptor (VEGFR) in the formation and alteration of vascularity. However, definitive reports regarding mutations associated with this locus and treatment experiences remain scarce. Herein, we report a clinical case of multiple venous malformations with mutations in VEGFR3 (<em>FLT4</em>). We implemented a comprehensive approach, including local lesion excision of the left foot and trunk, oral propranolol administration, and local physiotherapy. After two years of follow-up, the patient’s left foot venous malformation did not recur, and he expressed satisfaction with the outcomes of the combined therapy. This case offers valuable insights into the clinical management of this mutant type and similar presentations of multiple venous malformations.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"7 1","pages":"Pages 18-22"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reconstruction of the first web space post cicatricial contracture: Which technique to use?","authors":"Omar M. Nouh,&nbsp;Noura Khaled Abdelwahed,&nbsp;Wael S. Abdelnasser,&nbsp;Ahmed Ragab Morsi,&nbsp;Amr Ahmed Zaki,&nbsp;Shaimaa Mostafa","doi":"10.1016/j.cjprs.2025.01.001","DOIUrl":"10.1016/j.cjprs.2025.01.001","url":null,"abstract":"<div><h3>Background</h3><div>The first web space not only plays an integral role in hand functionality, but also holds an important aesthetic function for patients with cicatricial contractures, which hinders the ability to move joints, thereby restricting the performance of everyday activities. Therefore, a wide variety of reconstruction options are available. In this study, our main aim was to have a clear surgical plan prior to surgery according to preoperative findings and the degree of thumb abduction span.</div></div><div><h3>Methods</h3><div>This study was conducted at Kasr Al-Ainy Hospital. This cohort study included 33 patients with cicatricial first web space contractures who underwent reconstructive procedures to restore the first web space. Patients were assessed preoperatively and categorized according to the degree of contracture, and the reconstruction procedure was chosen accordingly. They were assessed using both objective and subjective methods.</div></div><div><h3>Results</h3><div>In this study, 33 cases of cicatricial contracture of the first web space due to physical or thermal trauma were included. Measurements of the change in the span of abduction were performed for all patients included in the study preoperatively and postoperatively. Skin grafting and skin substitutes had an average change in abduction span of 32.5° (± 14.4°), Z-plasty release had a mean of 30.59° (± 8.82°) increase in abduction span, regional flaps had an increase of 40.71° (± 12.39°), while distant flaps had an increase of 35° (± 3.54°).</div></div><div><h3>Conclusion</h3><div>No single reconstruction method can be used in all cases. When viewing a patient, one must consider that each individual has a unique representation. However, if we follow a systematic method for the initial evaluation, the most efficient flap can be chosen for each case, thus reducing the need for secondary procedures. Categorizing the cases according to the abduction span into mild, moderate, or severe forms is the first building block of this algorithm. Adjacent tissue condition, patient occupation, compliance, and the need to return to work are important factors.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"7 1","pages":"Pages 5-10"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast augmentation complications with three planes of implant placements","authors":"Haibo Zhao ,&nbsp;Nienwei Liu ,&nbsp;Zeren Shen ,&nbsp;Jinghong Xu","doi":"10.1016/j.cjprs.2024.12.002","DOIUrl":"10.1016/j.cjprs.2024.12.002","url":null,"abstract":"<div><div>Breast augmentation with implants is a popular cosmetic surgery that enhances breast volume and contour through various placement planes. In this review, we examine the impact of subglandular, subpectoral, and subfascial implant planes on postoperative outcomes and complication rates. Subglandular placement offers simplicity but is associated with higher risks of capsular contracture, hematoma, and rippling in patients with low tissue coverage. The subpectoral plane, widely adopted for its natural appearance and reduced capsular contracture risk, may cause dynamic deformity due to muscle contraction. Although technically challenging, the subfascial plane combines the benefits of soft tissue support and reduced implant displacement. We highlight the importance of choosing an optimal implant plane tailored to each patient’s anatomical and aesthetic needs to enhance surgical outcomes and minimize complications. Further research is needed to validate long-term efficacy, particularly for subfascial placement.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"7 1","pages":"Pages 45-48"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective function of adipocyte-derived extracellular vesicles and adipose stem cells in damage repair and regeneration","authors":"Yanwen Wang ,&nbsp;Poh-ching Tan ,&nbsp;Xuewen Xu ,&nbsp;Shuangbai Zhou","doi":"10.1016/j.cjprs.2024.11.007","DOIUrl":"10.1016/j.cjprs.2024.11.007","url":null,"abstract":"<div><div>Adipocyte-secreted extracellular vesicles (EVs) and adipose-derived stem cells (ADSCs) regulate physiological and pathological processes by delivering nucleic acids, proteins, and lipids. Both adipocyte- and ADSC-derived EVs regulate local inflammatory levels, tumor progression, and insulin sensitivity. These two types of EVs also have significant therapeutic effects on damage repair, including wound healing, angiogenesis, myocardial damage, vessel re-endothelialization, bone and cartilage regeneration, muscle repair, and nerve repair. With regard to wound healing, microRNA-21, microRNA-126, microRNA-31, and long non-coding RNA-H19 accelerate the proliferation and migration of fibroblasts, human immortalized keratinocytes, and endothelial cells via the PI3K/Akt/ERK pathway or <em>fibrillin 1</em>. ADSC-derived EVs contain various growth factors that are beneficial for wound healing. Numerous miRNAs in ADSC-derived EVs and β3-adrenergic receptors on brown adipocytes exhibit protective effects against myocardial infarction. Proteins in adipocyte- and ADSC-derived EVs play a role in promoting vessel re-endothelialization and regulating vasodilation. Angiogenesis is beneficial for the regeneration and repair of injured bone, cartilage, muscle, and nerves. Compared with adipocyte EVs, ADSC-EVs contain a greater variety of miRNAs and proteins that promote tissue regeneration. EV therapy is a promising cell-free therapy, and EV-loaded materials have been used for wound healing and myocardial damage. Future research will focus on identifying the molecules in EVs and the repair mechanisms that contribute to damage repair and regeneration. In addition, we aim to discover materials designed for slow release and specificity to facilitate tissue repair and optimize EV transportation.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"7 1","pages":"Pages 35-44"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends and dynamics in facelift surgery research: A bibliometric analysis of the top 50 most cited papers","authors":"Siddig Ibrahim Abdelwahab ,&nbsp;Abdullah Farasani ,&nbsp;Hassan Ahmad Alfaifi ,&nbsp;Waseem Hassan","doi":"10.1016/j.cjprs.2024.12.004","DOIUrl":"10.1016/j.cjprs.2024.12.004","url":null,"abstract":"<div><h3>Background</h3><div>Facelift procedures represent a critical area of aesthetic and reconstructive surgery that addresses the physical and psychological impacts of facial aging. Advancements in techniques and technologies over time have transformed the field, making it essential to assess the evolution of research trends. This study performed a bibliometric analysis of facelift research by examining the top 50 most cited publications to evaluate their contributions, thematic evolution, and collaborative networks.</div></div><div><h3>Methods</h3><div>The Scopus database was used to identify relevant publications. A total of 50 documents were selected, comprising 47 articles and 3 reviews published across 16 academic sources. The inclusion criteria focused on publications with substantial relevance to facelift research; this ensured comprehensive coverage of the topic. Key performance indicators (for the authors) such as the number of papers, total citations, h-index, g-index, m-index, HG composite, and Q2 index were calculated. Citation analysis and collaborative network mapping were conducted to identify the leading contributors, including authors, universities, countries, and sources.</div></div><div><h3>Results</h3><div>The findings indicated an annual growth rate of 1.34%, with an average document age of 29.4 years and an average citation count per document of 134.9. The analysis identified the top authors and their collaborative networks, along with key contributions from various universities, countries, and sources. The thematic evolution of facelift research was examined across these 50 papers; this revealed important trends and shifts within the field.</div></div><div><h3>Conclusion</h3><div>This bibliometric analysis offers valuable insights into the development and influence of facelift research over a 52-year span. It highlights significant contributors and outlines thematic shifts, providing directions for future research and collaboration in this field.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"7 1","pages":"Pages 11-17"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}