Chinese Journal of Plastic and Reconstructive Surgery最新文献

{"title":"Inferior alveolar nerve injury after sagittal split osteotomy of the mandible: A literature review","authors":"Iryna Logvynenko,&nbsp;Valeriia Bursova","doi":"10.1016/j.cjprs.2024.11.001","DOIUrl":"10.1016/j.cjprs.2024.11.001","url":null,"abstract":"<div><h3>Background</h3><div>Inferior alveolar nerve (IAN) injury is a serious potential complication of orthognathic surgery because the osteotomy cut-line during sagittal split osteotomy (SSO) of the mandible runs close to the mandibular canal. According to statistics, 9%–85% of patients who undergo such surgery suffer from complications. It causes neurosensory disorders (NSD) of the lower lip and chin with a wide variety of symptoms such as numbness, hypoesthesia, hyperesthesia, hypoalgesia, hyperalgesia, and allodynia. However, the accurate planning and thorough analysis using cone-beam computed tomography helps improve the predictability of possible IAN damage by considering the specific anatomical features of each patient and all risk factors. This study aimed to review the frequency of IAN occurrence, risk factors, and diagnostic, prophylactic, and treatment methods used for inferior alveolar nerve regeneration and IAN sensory disturbance recovery following SSO of the mandible.</div></div><div><h3>Methods</h3><div>We conducted a comprehensive literature search (2020–2024) across PubMed, Scopus, Google Scholar, and ScienceDirect, focusing on mandibular SSO complications, IAN damage, nerve regeneration, and treatments such as corticosteroids, vitamin B12, platelet concentrates, and low-level laser therapy. All systematic review, randomized controlled trial, controlled clinical trial, or retrospective/prospective study involving both animals and humans were included.</div></div><div><h3>Results</h3><div>Surgeons prescribed medicines for general therapy before surgery and applied intraoperative treatment methods to minimize the degree of NSD manifestation after surgery. Fortunately, majority instances of NSD recover spontaneously by 6 months after the operation; however, if symptoms persist after 1 year, it is considered permanent NSD, which may cause a significant decrease in quality of life. In the postoperative period, assessing neurosensory disturbances with subjective (questionnaires) and objective tests (light touch, 2-point discrimination tests, and others), or their combination, is necessary for determining the management. According to recent studies, dexamethasone, a complex of vitamin B, melatonin, and low-level lasers, is actively used in inferior alveolar nerve regeneration during and after SSO. Moreover, isolated studies have reported the intraoperative use of platelet concentrates during SSO.</div></div><div><h3>Conclusion</h3><div>The mentioned treatment methods demonstrated positive results in decreasing NSD. However, their effectiveness for IAN regeneration has not been sufficiently studied.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 4","pages":"Pages 219-227"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143100519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodegradable membrane for lower eyelid reconstruction: Clinical outcomes and patient satisfaction","authors":"Maria Cervatiuc ,&nbsp;Igor Vladimirovich Reshetov ,&nbsp;Eldor Jonnazarov ,&nbsp;Svetlana Vagovna Saakyan","doi":"10.1016/j.cjprs.2024.10.004","DOIUrl":"10.1016/j.cjprs.2024.10.004","url":null,"abstract":"<div><h3>Background</h3><div>Eyelid malignancies often require radical surgical intervention, with a major risk of tissue loss. Reconstructing the eyelid after such procedures is essential to restoring its protective function and aesthetic appearance. Traditional reconstruction methods involve using grafts from other sites of the body; however, these methods are limited by factors such as the availability of donor tissue, potential mismatches in tissue characteristics, and associated complications, including graft failure or scarring. Additionally, donor site morbidity and achieving a perfect match in texture and color remain challenging. Recent advances in biomaterials offer new possibilities for improving surgical outcomes by providing more biocompatible and flexible options that can be tailored to meet patient-specific needs, potentially reducing complications and improving functional and cosmetic outcomes.</div></div><div><h3>Methods</h3><div>The study included 61 patients who underwent lower eyelid reconstruction following the radical removal of malignant tumors. The patients were divided into the experimental (31 patients in whom a biodegradable Diplen membrane was used) and control (30 patients in whom the membrane was not used) groups. Patients were followed up for at least 1 year, with clinical outcomes and patient satisfaction carefully evaluated.</div></div><div><h3>Results</h3><div>The experimental group demonstrated significantly better outcomes regarding eyelid position and color, with fewer complications compared to the control group. Patient satisfaction was significantly higher in the experimental group, demonstrating a strong correlation with clinical outcomes. These findings highlight the effectiveness of the biodegradable Diplen membrane in achieving better functional and aesthetic outcomes.</div></div><div><h3>Conclusions</h3><div>Eyelid reconstruction using the biodegradable Diplen membrane offers excellent functional and aesthetic outcomes, significantly enhancing patient satisfaction, which is crucial for postoperative rehabilitation and improved quality of life.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 4","pages":"Pages 172-175"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large necrosis of the scalp following temporal catheter placement in an infant with severe acute malnutrition: A case report","authors":"Mongwa Mbikilile Justin ,&nbsp;Ntambala Prince ,&nbsp;Nanga Batende ,&nbsp;Alumeti Munyali","doi":"10.1016/j.cjprs.2024.10.001","DOIUrl":"10.1016/j.cjprs.2024.10.001","url":null,"abstract":"<div><div>Scalp necrosis is uncommon in malnourished children, yet temporal catheterization is frequently observed in pediatric hospital settings. The condition is characterized by a black, hard, and unresponsive scalp. Etiologies such as temporal arteritis, burns, and Takayasu’s disease, have been proposed. There is a decline in the use of peripheral catheter monitoring in hospitals. War-related food shortages and social instability significantly affect the trauma and risks that undermine the health, social, and psychological well-being of children. This report describes the case of a 5-month-old infant suffering from severe acute malnutrition following the abduction and subsequent release of his mother by armed individuals after one and a half weeks. The infant, who underwent temporal catheterization for medication administration, presented with extensive scalp necrosis. The necrotic tissue was surgically removed, and the malnutrition was successfully treated, resulting in a favorable clinical outcome. The mother received comprehensive mother-child care from a psychologist.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 4","pages":"Pages 196-198"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment and application of a fibrosis/scar biospecimen repository and systematic research platform","authors":"Zhiyuan Zhou,&nbsp;Ya Gao,&nbsp;Chiakang Ho,&nbsp;Dongsheng Wen,&nbsp;Yangdan Liu,&nbsp;Tingyu Tsai,&nbsp;Yuxin Lin,&nbsp;Qingfeng Li,&nbsp;Yifan Zhang","doi":"10.1016/j.cjprs.2024.10.003","DOIUrl":"10.1016/j.cjprs.2024.10.003","url":null,"abstract":"<div><div>Fibrosis is a pathological outcome of a dysregulated repair response to injury, which can occur in any organ and have devastating effects on hundreds of millions of patients worldwide. However, challenges remain in delineating the complex and dynamic network regulating fibrosis, as well as translating this information into effective anti-fibrotic treatments. A comprehensive understanding of existing methodologies and the development of new research tools are essential for ensuring the transferability of findings from bench to bedside. In this review, we present a framework consisting of a large biospecimen repository that integrates diverse patient cohorts with corresponding clinical data, and a systematic research platform incorporating multiple layers of experimental strategies, primarily focused on skin fibrosis. We summarize current advancements and the applications of various tools for preclinical fibrosis research and examine the limitations of traditional methods used to simulate and investigate biomechanical signals in the fibrotic environment. Importantly, we highlight the strengths of research techniques and translational approaches of varying physiological relevance developed by us over the past decade. Collectively, we emphasize a trend toward more faithfully replicating the functional, structural, and biological complexity of fibrosis while providing high spatio-temporal control over soluble cues and intricate interactions. Our comprehensive overview of methodology paves the way for minimizing batch-to-batch variation and improving the reproducibility of experimental systems.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 4","pages":"Pages 199-205"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric analysis of ChatGPT and plastic surgery research: Insights from diverse search strategies and co-word analysis","authors":"Siddig Ibrahim Abdelwahab ,&nbsp;Abdullah Farasani ,&nbsp;Hassan Ahmad Alfaifi ,&nbsp;Waseem Hassan","doi":"10.1016/j.cjprs.2024.10.002","DOIUrl":"10.1016/j.cjprs.2024.10.002","url":null,"abstract":"<div><h3>Background</h3><div>The rise of artificial intelligence in healthcare, particularly the development of large language models like ChatGPT, has opened new avenues for innovation in medical fields, including plastic surgery. ChatGPT offers potential applications in patient education, surgical planning, and decision-making support, making it an important research subject. However, there has been limited investigation into its impact on plastic surgery. The objective of this study was to investigate the progress of research on ChatGPT and plastic surgery, focusing on key contributors and emerging topics within the field.</div></div><div><h3>Methods</h3><div>Five distinct search strategies were employed to analyze relevant publications from the Scopus database.</div></div><div><h3>Results</h3><div>The analysis identified and presented the top authors, universities, countries, sponsors, and journals (within each search strategy). The co-authorship networks of authors, universities, and countries are graphically presented. The authors’ performance was depicted by various indicators, such as total publications, citations, h-index, g-index, and m-index. A co-word analysis revealed the focus of the papers, which were presented in 15 groups. This multifaceted approach provides a detailed understanding of key themes in the field.</div></div><div><h3>Conclusion</h3><div>This report offers a comprehensive overview of the current state of research at the intersection of ChatGPT and plastic surgery.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 4","pages":"Pages 185-195"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasma radiofrequency-assisted microsuction for the treatment of facial overfilled syndrome induced by diverse causes in Asians","authors":"Ming Ni ,&nbsp;Dong Wang","doi":"10.1016/j.cjprs.2024.11.003","DOIUrl":"10.1016/j.cjprs.2024.11.003","url":null,"abstract":"<div><h3>Background</h3><div>In Asia, facial overfilled syndrome (FOS) can arise from iatrogenic causes involving the excessive use of filling materials, as well as physiological causes such as adipose tissue hypertrophy type, age-related type, and lacuna type. This study aimed to demonstrate the safety and effectiveness of plasma radiofrequency-assisted microsuction (PRFAMS) for improving the appearance of FOS induced by various causes.</div></div><div><h3>Methods</h3><div>PRFAMS was performed on 84 anatomical regions of 37 female patients (including 12 with physiological causes, 6 with hyaluronic acid causes, and 19 with fat causes), aged between 20 and 50 years (mean, 35.9 years), who had FOS. Demographic and surgical data were collected retrospectively. Preoperative and postoperative photographs were taken, and satisfaction interviews were conducted at least six months after surgery.</div></div><div><h3>Results</h3><div>All the patients underwent successful surgery under local or intravenous anesthesia. Only four anatomic regions showed noticeable asymmetry postoperatively, requiring a secondary operation. Postoperative skin numbness, muscle paralysis, bruising, and minor contouring irregularities improved significantly within 2–3 weeks of recovery. Additionally, five patients with longer edema periods demonstrated substantial improvement after more than five weeks. No cases of skin necrosis, thermal injury, or other serious complications related to the device or procedure were reported. Ultimately, all patients expressed satisfaction with their outcomes.</div></div><div><h3>Conclusion</h3><div>The PRFAMS technique is a safe and effective method for treating FOS induced by various causes, while minimizing complications and ensuring high patient satisfaction.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 4","pages":"Pages 176-184"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute traumatic extratemporal facial nerve injury: A 5-year review","authors":"Enrique Chávez-Serna,&nbsp;Kenzo Alejandro Fukumoto-Inukai,&nbsp;Ricardo Romero-Caballero,&nbsp;José Eduardo Telich-Tarriba,&nbsp;Elsa Natalia Haro-Álvarez,&nbsp;Damián Palafox,&nbsp;Alexander Cárdenas-Mejía","doi":"10.1016/j.cjprs.2024.08.004","DOIUrl":"10.1016/j.cjprs.2024.08.004","url":null,"abstract":"<div><h3>Background</h3><div>Traumatic facial nerve injury is the second leading cause of facial paralysis, presenting significant challenges such as difficulties with eating, speaking, impaired vision, and loss of facial expression. Understanding these injuries is critical for plastic surgeons to optimize recovery and functional outcomes. This study examined our experience with acute traumatic extratemporal facial nerve injuries, focusing on their characteristics, the frequency of affected nerve branches, and identification using Seckel’s facial danger zones as anatomical landmarks. We also explored the implications of surgical management based on the current literature and our experience.</div></div><div><h3>Methods</h3><div>We reviewed 50 patients with acute traumatic extratemporal facial nerve injuries treated at Hospital General Dr. Manuel Gea González in Mexico City from January 2019 to January 2024. The collected data included demographics (age, sex, severity, and time to medical attention), injury mechanism, affected nerve branches using Seckel’s zones, and treatment methods.</div></div><div><h3>Results</h3><div>The majority of the patients were male (82%), with an average age of 29 ​± ​16 years. Sharp trauma from assault was the most common cause (66%). The buccal and frontal branches were most frequently affected, with Seckel zones IV and II involved in 46.86% and 33.33% of cases, respectively. Primary neurorrhaphy was performed in 96% of the patients.</div></div><div><h3>Conclusion</h3><div>The effective management of traumatic facial nerve injuries relies on understanding the characteristics of the injury and using anatomical landmarks for prompt localization. Primary neurorrhaphy is the preferred surgical approach, with nerve grafting being an alternative. Ideally, early intervention within 72 h is crucial for optimal nerve recovery.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 4","pages":"Pages 161-165"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143100520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New frontiers in scar management: Adipose tissue transplantation techniques","authors":"Ilgiz Gareev ,&nbsp;Ozal Beylerli ,&nbsp;Boxian Zhao ,&nbsp;Elmar Musaev","doi":"10.1016/j.cjprs.2024.09.001","DOIUrl":"10.1016/j.cjprs.2024.09.001","url":null,"abstract":"<div><div>A scar is a condition characterized by excessive repair of skin tissue, resulting in a fibroproliferative disorder marked by abnormal deposition of extracellular matrix. This disorder typically stems from deep dermal damage caused by burns or trauma and presents with symptoms such as itching and pain. Moreover, scarring can lead to disfigurement and psychological distress in affected individuals, making it a prevalent concern in burn plastic surgery outpatient clinics. In the current scar treatment landscape, one of the forefront approaches involves the grafting of adipose tissue and its components. This cutting-edge methodology encompasses various techniques, including nanofat grafting, adipose-derived stem cell matrigel applications, stromal vascular component transplantation, and adipose-derived mesenchymal stem cell infusion. Research in this domain has consistently demonstrated the remarkable capabilities of adipose tissue and its components in tissue regeneration, extracellular matrix remodeling, and anti-fibrotic actions. Notably, topical grafting of adipose tissue has emerged as a promising therapeutic avenue, showing significant improvements in both visual appearance and symptomatic relief associated with scars. The multifaceted functions of adipose tissue play a pivotal role in enhancing the overall outcomes of scar treatments. Therefore, this review aims to comprehensively evaluate and highlight the role of adipose tissue and its various components in scar treatment. By providing a theoretical foundation, this review aimed to serve as a valuable reference for improving the efficacy of scar management strategies.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 4","pages":"Pages 206-213"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143100518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing tissue regeneration studies with luciferase-transgenic rats and bioluminescence imaging: A comprehensive review","authors":"Poh-Ching Tan ,&nbsp;Eiji Kobayashi ,&nbsp;Qingfeng Li ,&nbsp;Shuangbai Zhou","doi":"10.1016/j.cjprs.2024.09.003","DOIUrl":"10.1016/j.cjprs.2024.09.003","url":null,"abstract":"<div><div>Bioluminescence imaging (BLI) in rodent models has revolutionized preclinical research in recent decades, enabling precise and noninvasive observation of cellular and molecular processes <em>in vivo</em>. Among various bioluminescent systems, the firefly luciferase-luciferin system is one of the most widely employed for <em>in vivo</em> cell tracking. This comprehensive review focuses on using luciferase-transgenic (Luc-Tg) rat models, known as firefly rats, in conjunction with BLI to investigate tissue regeneration and stem cell dynamics. Compared with other imaging modalities, BLI offers enhanced tissue penetration, reduced background noise, and the capacity to perform longitudinal studies with fewer animals, aligning with ethical research principles. Applications of Luc-Tg rats in fat grafting, soft tissue expansion, hair growth cycle analysis, and other skin studies are discussed, demonstrating the versatility and precision of BLI in tracking complex biological processes. Integrating advanced analytical and genome-editing techniques with BLI promises to enhance data interpretation’s accuracy and efficiency. These advancements have deepened our understanding of the cellular fate and mechanisms underlying tissue regeneration, presenting promising avenues for optimizing therapeutic strategies in reconstructive surgery and regenerative medicine. Combining luciferase reporter genes and BLI is crucial to unraveling complex biological phenomena, advancing soft tissue regeneration research, and developing innovative therapeutic strategies for various medical conditions.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 4","pages":"Pages 214-218"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of negative pressure wound therapy on inflammatory cell counts in porcine deep dermal burn wound models","authors":"Giri Yurista ,&nbsp;Nabilah Anisa Novebri ,&nbsp;Irianiwati ,&nbsp;Muhammad Rosadi Seswandhana","doi":"10.1016/j.cjprs.2024.09.002","DOIUrl":"10.1016/j.cjprs.2024.09.002","url":null,"abstract":"<div><h3>Background</h3><div>The inflammatory phase of acute burns can last for 7 days. Meanwhile, severe burns may exhibit persistent inflammation long after the initial tissue damage. Negative pressure wound therapy (NPWT) is recommended to treat various lesions, including burns. This study aimed to compare the number of inflammatory cells on days 3, 14, and 21 in deep dermal burns treated with two different therapies.</div></div><div><h3>Methods</h3><div>This experimental study was conducted at the Prof. Soeparwi Veterinary Hospital, Yogyakarta, from February to September 2022. A total of 36 wounds created in 10-kg Yorkshire pig burn models were subjected to one of the following treatments: 0.9% sodium chloride or NPWT. These wounds were then sampled as paraffin blocks for microscopic inflammatory cell counts by an anatomical pathology specialist. Comparative analyses of lymphocytes, neutrophils, and plasma cells were performed using IBM SPSS version 22 for Windows.</div></div><div><h3>Results</h3><div>A significant difference was found only in neutrophil counts on day 3 (5.30 ​± ​5.41), day 14 (42.83 ± 38.58), and day 21 (9.80 ​± ​8.97) (<em>P</em>=0.009), with notable changes from day 3 to day 14 (37.53 ​± ​40.51; <em>P</em>=0.043) and day 14 to day 21 (−33.03 ​± ​42.79; <em>P</em>=0.049). Meanwhile, no significant differences were found in either lymphocytes or plasma cells between days in either treatment group.</div></div><div><h3>Conclusion</h3><div>NPWT effectively reduced neutrophil counts on day 21 of treatment, indicating its beneficial effects in preventing prolonged inflammation during wound healing. This demonstrates its potential as an alternative dressing therapy for deep dermal burn injuries.</div></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 4","pages":"Pages 166-171"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143156124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}