Analytical Methods最新文献

{"title":"Honeysuckle-derived carbon dots as fluorescent nanoprobes for determination of sunset yellow and cell imaging","authors":"Lina Yu, Xue Cao, Xiaoqi Wang, Lili Yuan, Xin Chen, Caiyun Wang, Congying Shao and Shun Lu","doi":"10.1039/D5AY01132A","DOIUrl":"10.1039/D5AY01132A","url":null,"abstract":"<p >Sunset yellow (SY) is a widely used food and pharmaceutical colorant, but concerns over its safety highlight the need for sensitive and accurate detection methods. In this work, carbon dots were synthesized from the herbal medicine Honeysuckle (H-CDs). H-CDs exhibited excellent luminescent properties, structural stability, and remarkable selectivity and sensitivity toward SY. This enabled the development of a label-free fluorescent sensor with an ultralow detection limit of 11 nM and a linear detection range of 0–40 μM for SY. The sensor was successfully applied to detect SY in fruit juice samples, yielding recovery rates between 96.1% and 101.0%, demonstrating its practical potential. Additionally, smartphone-assisted SY detection allows convenient real-time, on-site screening. H-CDs also showed low cytotoxicity (cell viability &gt;95% at concentrations up to 2.0 mg mL<small>⁻¹</small>), indicating promise for bioimaging and cellular imaging applications. This work presents a sustainable, eco-friendly synthesis of carbon dots with versatile applications in food safety and biological fields.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 36","pages":" 7178-7183"},"PeriodicalIF":2.6,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144936410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-performance identification of insulating materials by using generalized spectrum in laser-induced breakdown spectroscopy","authors":"Junfei Nie, Furong Chen, Ting Luo, Jinke Chen, Jiapei Cao, Qiang Huang, Deng Zhang and Zhenlin Hu","doi":"10.1039/D5AY01151E","DOIUrl":"10.1039/D5AY01151E","url":null,"abstract":"<p >The high-performance identification of insulating materials is crucial for reducing resource waste, minimizing pollution, and promoting resource recycling. To achieve this, a novel method based on laser-induced breakdown spectroscopy (LIBS), named the generalized spectrum method (GSM-LIBS), was proposed in this study. Compared to traditional dimensionality reduction methods such as PCA, GSM-LIBS outperforms by integrating multiple spectral features, preserving both global and local information that may be lost in PCA-based methods. GSM-LIBS not only effectively reduces the spectral dimensions but also extracts more key features, such as peak intensity, integral intensity, intensity ratio, radiation background, and spectral shape. These features help retain important information from the spectrum, providing more precise details such as plasma state, element concentration, and spectral characteristics, thereby significantly improving analysis performance. To verify the effectiveness of GSM-LIBS, this method was applied to the classification study of seven types of insulating materials and compared with principal component analysis (PCA-LIBS). To ensure the general applicability of this study, two traditional machine learning models, <em>k</em>-nearest neighbor (KNN) and support vector machine (SVM), and one deep learning model, neural network (NN), were used. For the machine learning models, the accuracy of the KNN and SVM classification models on the prediction set improved from 0.935 and 0.965 to 0.979 and 0.996, respectively. For the deep learning model, the performance of the NN classification model was also significantly improved, with accuracy increasing from 0.984 to 0.994. These experimental results strongly demonstrate the feasibility and effectiveness of GSM-LIBS in effectively reducing the spectral dimensions while retaining key information.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 35","pages":" 6982-6988"},"PeriodicalIF":2.6,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144936291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender profiling based on amino acids in fingermark residues: a study on stability†","authors":"Lu-Chuan Tian, Ya-Bin Zhao, Shi-Si Tian, Yanda Zheng, Shuo Zhang and Linyuan Fan","doi":"10.1039/D4AY01954G","DOIUrl":"10.1039/D4AY01954G","url":null,"abstract":"<p >Chemical residues in fingermarks have been proven to assist in suspect tracing and population profiling. However, the composition and levels of these chemicals are derived from complex metabolic systems and are easily influenced by biological activities, which has hindered judicial institutions worldwide from establishing standardized analytical procedures. To develop a rapid, accurate, and straightforward analytical method, this study employed UPLC-QqQ-MS/MS to quantify amino acid levels in fingermark residues, integrating machine learning techniques and intelligent optimization algorithms for gender prediction. We evaluated whether the relative concentrations of amino acids in fingermark residues—normalized to endogenous serine—could reliably serve as indicators for gender determination, while also examining the effects of donors' physical activity levels, living regions, and fingermark aging periods (0–64 days) on gender classification. The results indicate that significant differences in gender were observed. Under various physical activity frequencies, leucine and valine consistently exhibited statistically significant differences, while across different living regions, valine and phenylalanine remained significant. Moreover, a comprehensive Mann–Whitney significance analysis, followed by Bonferroni correction on all measured fingermarks, revealed that the concentrations of Phe, Ile, Leu, Val, Pro, Asn, Glu, His, and Asp differ significantly between genders. Four classification models were developed based on the relative abundances of amino acids in fingermark residues, and their hyperparameters were optimized using the particle swarm optimization algorithm. Ultimately, the PSO-BP model achieved the highest accuracy of 84.49%. In summary, this study introduces a novel approach utilizing the relative concentrations of amino acids in fingermarks for gender determination. The established method is simple, accurate, and does not require derivatization, making it less susceptible to transfer loss, aging time, or individual factors. The developed models exhibit high classification accuracy and robust generalization ability. The conclusions from this study may provide valuable references for the development of sensitive amino acid reagents and also address a gap in the stability discussion of fingermark residue research.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 35","pages":" 7005-7018"},"PeriodicalIF":2.6,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144936367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel label-free NIR aptasensor based on triphenylmethane dyes for rapid detection of salicylic acid","authors":"Lingli Bu, Xinxin Li, Junhao Hu, Mengyao Liang, Luyao Li and Teck-Peng Loh","doi":"10.1039/D5AY01023C","DOIUrl":"10.1039/D5AY01023C","url":null,"abstract":"<p >Salicylic acid (SA) is a critical phytohormone involved in plant growth, development, and defense responses, making its precise quantification essential for both agricultural management and environmental monitoring. Here, we report a novel label-free near-infrared aptasensor (NIRApt) for the rapid and sensitive detection of SA, utilizing a rationally selected triphenylmethane (TPM) dye. Through systematic screening, ethyl violet (EV) was identified as the optimal fluorophore, showing pronounced fluorescence enhancement upon binding to a SA-specific aptamer. The sensing mechanism relies on target-induced competitive displacement, in which SA binding triggers the release of EV from the aptamer complex, resulting in a marked quenching of the fluorescence signal. The developed NIRApt exhibits high specificity and sensitivity, with a detection limit of 0.63 μM and a broad linear range of 0–30 μM. Remarkably, it demonstrates an ultrafast response within one minute, highlighting its efficiency for rapid quantitative detection. Its practicality was validated in spiked cherry tomato samples, achieving high detection accuracy. This platform offers key advantages including label-free operation, low background signal, minimal sample preparation and rapid response, demonstrating strong potential for food safety analysis and environmental monitoring of SA.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 36","pages":" 7327-7333"},"PeriodicalIF":2.6,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantification and discovery of quality control chemical markers for Shouhui Tongbian capsules by UPLC-MS/MS","authors":"Jieting Zhang, Shuo Diao, Zhen Huang, Mengyuan Wu, Xintong Wang, Yiran Zhao, Mingming Yu, Xianzhen Wang, Jingchun Yao, Guimin Zhang, Sherwin K. B. Sy, Zhihua Lv and Hai Yang","doi":"10.1039/D5AY00842E","DOIUrl":"https://doi.org/10.1039/D5AY00842E","url":null,"abstract":"<p >Guided by the principles of Analytical Quality by Design (AQbD), a highly selective and sensitive LC-MS/MS method was established for the simultaneous quantification of 15 compounds in Shouhui Tongbian capsules, enabling their effective quality control. The separation was carried out on a BEH C18 column (1.7 μm, 2.1 × 100 mm) with a mobile phase comprising 0.1% formic acid in 3 mM ammonium acetate aqueous solution and methanol (60 : 40, v/v) at a flow rate of 0.30 mL min<small>⁻¹</small>. The method exhibited good linearity within a certain concentration range (<em>R</em><small>²</small> &gt; 0.9906) depending on the compound; the precision ranged from 0.6% to 14.7% and accuracy was within 11.2%. Among the 15 detected compounds, aloin had the highest content in the Shouhui Tongbian capsules, reaching 227.3780 mg g<small>⁻¹</small>, followed by betaine and <small>L</small>-hydroxyproline, with concentrations of 1.3204 mg g<small>⁻¹</small> and 1.2929 mg g<small>⁻¹</small>, respectively. This method simultaneously detected the content of 15 compounds in five batches of Shouhui Tongbian capsules.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 34","pages":" 6821-6830"},"PeriodicalIF":2.6,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring toluene diisocyanate concentrations in accordance with the ACGIH® inhalable fraction and vapor (IFV) notation","authors":"Charles Larocque, Pierre-Luc Cloutier, Sébastien Gagné, Loïc Wingert, Sylvain Canesi, Jacques Lesage and Simon Aubin","doi":"10.1039/D5AY00863H","DOIUrl":"10.1039/D5AY00863H","url":null,"abstract":"<p >Toluene diisocyanate (TDI) is an irritant (skin, eye and respiratory) and a sensitizer. This compound is used to manufacture polyurethane materials such as flexible foams. The use of isocyanates may lead to exposure by inhalation and/or skin contact and isocyanates are recognized as a cause of occupational asthma. The American Conference of Governmental Industrial Hygienists (ACGIH®) recommends a threshold limit value (TLV) for TDI of 1 part per billion (ppb) (7 μg m<small>⁻³</small>) with the inhalable fraction and vapor (IFV) notation. This notation means that the inhalable fraction of particles and the vapor phase of TDI may contribute to the exposure, and therefore the evaluation methods must comply with the IFV notation. This study aimed at developing and validating a TDI measurement method, compliant with the ACGIH IFV notation, using an IOM sampler with an impregnated filter. The new sampling method (IOM-IFV) used an IOM sampler (stainless steel cassette) with a glass fiber filter coated with 1,2-(methoxyphenyl)piperazine (MP) and diethyl phthalate. The sample was extracted using acetonitrile and analyzed by UPLC-MS. This application of the IOM sampler for such a reactive chemical was characterized and tested in the laboratory to ensure efficient TDI recovery from both spiked samples and air samples. Based on a sampling time of 2 hours, the method has a measuring range of 0.3 to 15 μg m<small>⁻³</small>. At its reporting limit, the method is capable of measuring 8% of the 15 min short-term TLV (36 μg m<small>⁻³</small>). Method comparisons using a laboratory generation system showed that, under the conditions tested, the OSHA 5002 method was in agreement with the new IOM-IFV method. The ISO 17334-1 method showed a significant negative bias of −40% compared to the IOM-IFV method. The new IOM-IFV method demonstrated its suitability for measuring exposure to TDI for comparison with the ACGIH® TLVs, <em>i.e.</em> the STEL (15 min) and the TWA (8 h). A comparative study should be carried out in occupational settings to confirm the conclusions obtained in the laboratory.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 37","pages":" 7491-7499"},"PeriodicalIF":2.6,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous determination of ten sweeteners in soybean products using PRiME HLB purification combined with ultra-high-performance liquid chromatography-tandem mass spectrometry","authors":"Yi Bao, Jinping Guo, Jinming Wang, Dan Li, Zhuo Lv, Xu Zhang, Xue Yang, Zeyue Gao and Lanying Zhou","doi":"10.1039/D5AY00897B","DOIUrl":"10.1039/D5AY00897B","url":null,"abstract":"<p >A method for determination of ten kinds of sweeteners in soybean products by multi-plug filtration cleanup (<em>m</em>-PFC) combined with ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was established. The sample was extracted with acetonitrile (containing 1% formic acid), degreased by using <em>n</em>-hexane liquid–liquid extraction and purified by solid phase extraction using an <em>m</em>-PFC column (Oasis PRiME HLB). The analytes were separated by using a Waters ACQUITY UPLC® BEH C<small>₁₈</small> (2.1 mm × 150 mm, 1.7 μm) column, and gradient eluted with a mixed solution of (5 mmol L<small>⁻¹</small> ammonium formate +0.1% formic acid) and acetonitrile. The mass spectrometric acquisition was performed by multiple-reaction monitoring (MRM) in both negative and positive ionization mode. Quantitative analysis was performed using an external standard method with matrix-matched calibration curves. Under optimal conditions, a total of ten target compounds were well separated within 10 min, and a good linearity was obtained in the concentration range of 5.00–500 μg L<small>⁻¹</small> with correlation coefficients greater than 0.99, and the limits of detection (LODs) and quantification (LOQs) for ACE-K, SAC and SCL were 25.0 and 50.0 μg kg<small>⁻¹</small>; the limits of detection (LODs) and quantification (LOQs) for CYC, ASP, ALI, RBA, STV, ADV and NEO were 12.5 and 25.0 μg kg<small>⁻¹</small>,respectively. The recoveries of the ten sweeteners in soymilk samples ranged from 76.9% to 115% at low, medium and high spiked levels (25.0–50.0 μg kg<small>⁻¹</small>, 50.0–100 μg kg<small>⁻¹</small>, and 250–500 μg kg<small>⁻¹</small>), with precisions (RSD) in the range of 0.62–3.98%. This method is simple, rapid, accurate and sensitive, which greatly improves the efficiency of sample analysis and the accuracy of qualitative and quantitative analysis results of the target substances. It could meet the needs of quantitative analysis and qualitative screening of sweeteners in bulk soybean product samples, and provide technical support for rapid analysis of sweeteners in soybean products. It is of great significance for the analysis of trace components of sweeteners in soybean products.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 37","pages":" 7482-7490"},"PeriodicalIF":2.6,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of inorganic chemical constituents in the secretions of Populus euphratica","authors":"Yuan Yuan Chen, Zulhumar Tursun, Turghun Muhammad, Ümüt Halik, Almire Dolkun and Munire Aimaitiniyazi","doi":"10.1039/D5AY00945F","DOIUrl":"https://doi.org/10.1039/D5AY00945F","url":null,"abstract":"<p > <em>Populus euphratica</em> (<em>P. euphratica</em>) is a key desert riparian plant species in central Asia. This species has adapted to harsh habitat conditions by excreting salts in the form of <em>P. euphratica</em> secretion (PES). PES is known to have therapeutic benefits for ailments such as sore throats, gastrointestinal disorders, and neurasthenia. Meanwhile, local inhabitants harvest PES for the preparation of an alkaline paste, a digestive beverage for their diet and flour leavening agent. Despite its various uses, the chemical composition of PES remains to be elucidated. In this study, the elemental and ionic composition of PES was quantitatively analyzed using elemental analysis, ICP-OES, ion chromatography, and potentiometric titration. The main inorganic compounds were determined by X-ray diffraction. Na, K, Ca, Mg, Cl<small>⁻</small>, HCO<small>₃</small><small>⁻</small> and SO<small>₄</small><small>²⁻</small> were identified in PES. Na<small>₂</small>CO<small>₃</small>·NaHCO<small>₃</small>·2H<small>₂</small>O (Trona) and KCl, the two main components, were found and quantified in PES for the first time. Additionally, NaHCO<small>₃</small>, NaCl and SiO<small>₂</small> were also detected in PES. This work thoroughly characterized PES, a highly nutritious and culturally valued food material, through qualitative and quantitative analyses, fully elucidating its inorganic chemical composition. These findings address several gaps in the fundamental composition data of PES and support its physiological functions in plants and potential health benefits in traditional applications.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 34","pages":" 6810-6820"},"PeriodicalIF":2.6,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Boron nitride-based magnetic nanocomposite for magnetic solid-phase extraction coupled with HPLC-UV for simultaneous determination of three tetracyclines in pork, egg, and milk","authors":"Junmei Li, Weiran Wang, Yupeng Sun, Yan Fu, Haoqi Zhang, Bingrong Wang, Chunying Wang and Xue Xiong","doi":"10.1039/D5AY01104C","DOIUrl":"10.1039/D5AY01104C","url":null,"abstract":"<p >Tetracycline antibiotic residue in food is of vital significance for public health. Hexagonal boron nitride (h-BN)-based materials are excellent absorbents for antibiotics, and modification of the h-BN surface would improve its adsorption ability. In this study, a Fe<small>₃</small>O<small>₄</small>-modified h-BN nanocomposite (Fe<small>₃</small>O<small>₄</small>@h-BN) was fabricated by a simple one-step coprecipitation method. The nanocomposite was characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, and vibrating sample magnetometer (VSM). Fe<small>₃</small>O<small>₄</small>@h-BN was used as a magnetically recyclable adsorbent for magnetic solid phase extraction (MSPE) of tetracycline (TC), oxytetracycline (OTC), and chlortetracycline (CTC), and the adsorption performance was investigated under different influencing factors, including contact time, adsorbent dosage, pH conditions, and ionic strength. The nanocomposite Fe<small>₃</small>O<small>₄</small>@h-BN was used for the analysis of three tetracyclines (TCs) in pork, egg, and milk samples using MSPE coupled with high-performance liquid chromatography equipped with a UV detector (HPLC-UV). Under the optimized experimental conditions, the recoveries measured for pork, egg, and milk samples ranged from 84.2% to 96.6%, 92.8% to 108.2%, and 84.1% to 102.6%, respectively, with relative standard deviations (RSDs) of 0.3–9.4%, 0.8–9.7%, and 1.3–7.1%, respectively. This work presents a simple and effective method for antibiotic analysis in food samples.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 34","pages":" 6847-6858"},"PeriodicalIF":2.6,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harm reduction of heated tobacco in outdoor spaces in place of burnt tobacco smoking","authors":"Daniel Gallart-Mateu, Esther Fuentes-Ferragud, Clara Coscollà and Miguel de la Guardia","doi":"10.1039/D5AY00954E","DOIUrl":"10.1039/D5AY00954E","url":null,"abstract":"<p >The effect of heat-not-burn (HnB) tobacco in smoking practices has been evaluated in outdoor scenarios by using gas sensors. The data obtained confirmed that the use of HnB tobacco has a minimal impact on ambient suspended particles, that is, PM<small>₁₀</small> and PM<small>_2.5</small> levels, resulting in approximately half the effect of combustion tobacco, in line with harm reduction principles. In addition, using HnB products outdoors did not lead to high levels of VOCs in the surrounding air nor in the breath of people who use them, whether directly or through passive exposure. This contrasts sharply with the increased levels found in the breath of both active and passive users of traditional tobacco cigarettes. On the other hand, liquid chromatography high resolution mass spectrometry (LC-HRMS) analysis of HnB passive volunteers' exhaled breath extracts showed typical compounds of tobacco manufacturing products.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 34","pages":" 6831-6839"},"PeriodicalIF":2.6,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/ay/d5ay00954e?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}