Analytical Methods最新文献

{"title":"Ultrasensitive detection of E. coli using bioinspired based platform†","authors":"Sawsan Almohammed, Tristan Nolan, Niamh Martin, Wim G. Meijer, Brian J. Rodriguez and James H. Rice","doi":"10.1039/D4AY01677G","DOIUrl":"10.1039/D4AY01677G","url":null,"abstract":"<p >Bacterial infections are a leading cause of mortality worldwide, underscoring the urgent need for effective detection methods. This study introduces a novel approach that combines surface-enhanced Raman spectroscopy (SERS) with an electro-optic technique for bacterial detection. The method utilizes a metal–semiconductor substrate that, when activated by an external electric field, significantly amplifies the SERS signal intensity. We validated this approach through a proof-of-concept study, demonstrating that the SERS signal of Gram-negative <em>Escherichia coli</em> can be enhanced tenfold by applying an electric field, confirming the method's efficacy for bacterial detection. Our findings highlight the potential of this rapid, label-free biosensor for pathogen detection with near single-cell sensitivity.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 1","pages":" 10-14"},"PeriodicalIF":2.7,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid low-level nitrate determination by UV spectroscopy in the presence of competing ions†","authors":"S. E. Mackay, D. S. Eldridge and F. Malherbe","doi":"10.1039/D4AY01641F","DOIUrl":"10.1039/D4AY01641F","url":null,"abstract":"<p >The presence of excessive nitrate in environmental and drinking water even at low levels can pose both environmental and health hazards. Because of this, various methods for its removal have been investigated. Essential to conducting such research is a method to reliably quantify nitrate in relevant matrices. However, current approaches have drawbacks related to cost, analysis time or health hazards. This study evaluates a UV spectroscopy-based method for nitrate determination, suitable for quantifying low nitrate concentrations in the presence of bicarbonate, sulfate, chloride and phosphate. The limits of detection and quantification were found to be 0.003 ppm N and 0.0077 ppm N respectively, lower than that observed in the ion chromatography method it was compared to. Additionally, a calibration curve created with 11 standards ranging from 0 to 2.5 ppm N demonstrated an exceptionally strong correlation, with an <em>R</em><small>²</small> value greater than 0.9999. This method is developed with a focus on accessibility and speed, minimising hazards and waste generation for reduced environmental footprint. The effects of contaminants introduced through the use of commercial laboratory consumables are also discussed.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 48","pages":" 8471-8481"},"PeriodicalIF":2.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A high-performance ionic liquid-based microextraction (ILBME) method for the trace determination of paroxetine as a pharmaceutical pollutant in environmental and biological samples†","authors":"Mehdi Hosseini","doi":"10.1039/D4AY01668H","DOIUrl":"10.1039/D4AY01668H","url":null,"abstract":"<p >A high-performance ionic liquid-based microextraction technique utilizing a task-specific imidazolium-based ionic liquid was employed for the analysis of paroxetine as a pharmaceutical pollutant at trace levels in some real environmental and biological samples. An ionic liquid, 3-(2-hydroxy-4-(isopropylamino)butyl)-1-methylimidazolium chloride, abbreviated to [Hibmim][Cl], was synthesized with a yield of 90.4%. Its physical properties were determined and characterized using FTIR, HNMR, CNMR, and CHNO techniques. The ionic liquid was then used for preconcentration prior to the determination of paroxetine in water and urine samples. Specifically, the ionic liquid served as both the extractor and the extracting phase, demonstrating high efficiency in extracting paroxetine from real samples. Density functional theory (DFT) studies, as well as UV-Vis and FTIR analyses indicated that the ionic liquid could successfully form a chelate with paroxetine <em>via</em> hydrogen bonds. To confirm the method efficacy for analyzing real samples, the figures of merit and parameters affecting the microextraction procedure were assessed and optimized. Under optimal conditions, the limit of detection, limit of quantification, linear dynamic range, intra-day and inter-day relative standard deviations, preconcentration factor, and enhancement/enrichment factor were determined to be 0.42 μg L<small>⁻¹</small>, 1.41 μg L<small>⁻¹</small>, 5.0–60.0 μg L<small>⁻¹</small>, 2.58%, 3.83%, 197.3, and 193.3, respectively. The maximum yield of paroxetine extraction under optimal conditions was 98.8%. Finally, to evaluate the method validity, a standard addition procedure was used, yielding satisfactory recovery values ranging from 98.7% to 101.2%.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 48","pages":" 8457-8470"},"PeriodicalIF":2.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smartphone-assisted colorimetric detection of nickel(ii) ions using a novel benzothiazole–quinoline dyad in semi-aqueous media†","authors":"Suman Joseph, Pranati Somkuwar, Gayathri G. Menon, Anjana C. Rajesh, Pravinkumar Selvam, Selva Kumar Ramasamy, R. Bhaskar and S. K. Ashok Kumar","doi":"10.1039/D4AY01574F","DOIUrl":"10.1039/D4AY01574F","url":null,"abstract":"<p >In this study, we present three different approaches for the colorimetric detection of Ni<small>²⁺</small> ions using a specifically designed benzothiazole–quinoline dyad (<strong>L</strong>) synthesized <em>via</em> the Knoevenagel condensation reaction in high yield. The unique properties of <strong>L</strong> enable a rapid and selective response to Ni<small>²⁺</small> ions, making it an ideal probe for practical applications. The probe <strong>L</strong> shows a pale yellow color under normal conditions. Upon interaction with Ni<small>²⁺</small> ions, <strong>L</strong> undergoes a significant color change from pale yellow to bright orange, allowing for visual detection in semi-aqueous media. This rapid colorimetric response enables real-time monitoring of Ni<small>²⁺</small> concentrations. The absorption maximum of <strong>L</strong> undergoes a bathochromic shift in the presence of Ni<small>²⁺</small> ions due to ligand-to-metal charge transfer (LMCT). The probe <strong>L</strong> could form a 2 : 1 [<strong>L</strong> : Ni<small>²⁺</small>] stoichiometric complex, confirmed through Job's plot and ESI mass analysis with an estimated association constant of 2.61 × 10<small>⁶</small> M<small>⁻²</small>. The probe <strong>L</strong> could detect Ni<small>²⁺</small> concentration down to 61 nM, 106 nM, and 129 nM <em>via</em> a UV-Vis spectrophotometer, smartphone-assisted RGB method, and test paper strip analysis. The binding mechanism of probe <strong>L</strong> with metal ions was studied using <small>¹</small>H NMR, ESI mass spectrometry, and DFT calculations. The zeta potential analysis showed a potential of −28.38 mV for the free ligand and +12.09 mV upon complexation with Ni<small>²⁺</small>. More importantly, the potential application of probe <strong>L</strong> includes the quantification of Ni<small>²⁺</small> ions in various water samples through all three sensing approaches.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 2","pages":" 265-274"},"PeriodicalIF":2.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction: Novel 8,9-dihydroxy-7-methyl-12H-benzothiazolo[2,3-b]quinazolin-12-one multiwalled carbon nanotubes paste electrode for simultaneous determination of ascorbic acid, acetaminophen and tryptophan","authors":"Manzarbanou Asnaashariisfahani, Hassan Karimi-maleh, Hamid Ahmar, Ali A. Ensafi, Ali R. Fakhari, Mohammad A. Khalilzadeh and Fatemeh Karimi","doi":"10.1039/D4AY90149E","DOIUrl":"https://doi.org/10.1039/D4AY90149E","url":null,"abstract":"<p >Retraction of ‘Novel 8,9-dihydroxy-7-methyl-12<em>H</em>-benzothiazolo[2,3-<em>b</em>]quinazolin-12-one multiwalled carbon nanotubes paste electrode for simultaneous determination of ascorbic acid, acetaminophen and tryptophan’ by Manzarbanou Asnaashariisfahani <em>et al.</em>, <em>Anal. Methods</em>, 2012, <strong>4</strong>, 3275–3282, https://doi.org/10.1039/C2AY25418B.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 47","pages":" 8285-8285"},"PeriodicalIF":2.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/ay/d4ay90149e?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142778028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction: Modified multiwalled carbon nanotubes paste electrode as a sensor for the electrocatalytic determination of N-acetylcysteine in the presence of high concentrations of folic acid","authors":"Mohsen Keyvanfard, Ali A. Ensafi, Hassan Karimi-Maleh and Khadijeh Alizad","doi":"10.1039/D4AY90150A","DOIUrl":"https://doi.org/10.1039/D4AY90150A","url":null,"abstract":"<p >Retraction of ‘Modified multiwalled carbon nanotubes paste electrode as a sensor for the electrocatalytic determination of <em>N</em>-acetylcysteine in the presence of high concentrations of folic acid’ by Mohsen Keyvanfard <em>et al.</em>, <em>Anal. Methods</em>, 2012, <strong>4</strong>, 3268–3274, https://doi.org/10.1039/C2AY05802B.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 47","pages":" 8284-8284"},"PeriodicalIF":2.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/ay/d4ay90150a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142778027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of matrix-matched calibration standards for accurate determination of elemental concentrations in uric acid stones by LA-ICP-MS","authors":"Qingling Zhou, Xinyi Chen, Duoduo Ao, Hui Hu, Jianzong Zhou, Yongmei Hu, Wanqing Yang, Yuqiu Ke, Xiaoqing Yi and Hui Xu","doi":"10.1039/D4AY01440E","DOIUrl":"10.1039/D4AY01440E","url":null,"abstract":"<p >Accurate determination of elemental concentrations in uric acid (UA) stones is crucial for understanding their formation process. However, the lack of matrix-matched calibration standards has limited the application of laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) in this field. This study addresses this limitation by preparing a synthetic UA precipitate (UA-1) doped with 17 elements using a recrystallization method. Reference concentrations of these elements were measured using pneumatic nebulization-ICP-MS (PN-ICP-MS) for calibration purposes. The synthetic standard was characterized through 30 random spot analyses, demonstrating a homogeneity of approximately 5%. Using this synthetic standard, a reliable analytical method was developed, achieving limits of detection (LODs) ranging from 0 to 0.42 μg g<small>⁻¹</small>. The method's accuracy, with relative deviations between −8.33% and 0 and correlation coefficients (<em>R</em><small>²</small>) greater than 0.99, confirms its reliability. Additionally, elemental distribution differences observed across various zones in a real UA stone suggest that this method offers a promising approach for the precise analysis of elemental concentrations in UA stones.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 2","pages":" 246-255"},"PeriodicalIF":2.7,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142737722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the performance of 3D printed (spectro)photometers based on multi-channel color sensors for colorimetric determinations†","authors":"Caio C. S. Machado, Alegre N. S. Cadeado, Yugo S. N. da Mota, João F. S. Petruci and Sidnei G. Silva","doi":"10.1039/D4AY01831A","DOIUrl":"10.1039/D4AY01831A","url":null,"abstract":"<p >Portable and affordable (spectro)photometers based on digital color sensors are gaining significance in analytical chemistry due to their compact design, cost-effectiveness and integration capabilities. Despite their inherent straight-forward operation, various digital light sensors with distinct performance and optical characteristics are available on the market. For instance, AS7341 and AS7262 are multi-channel color sensors that covers eight and six spectra regions, respectively, while TCS34725 operates using three channels (red, green, and blue). In this study, the analytical performance of 3D printed, reflectance-based (spectro)photometers employing different digital color sensors was evaluated. Spectra resolution, signal gain and LED current were systematically evaluated to ensure the best performance for each sensor. The sensors' analytical performance was obtained by quantifying different dyes in aqueous solutions and sunset yellow in beverages as a proof-of-concept. All three sensors presented sub-millimolar detection with excellent linear coefficient (<em>r</em><small>²</small> &gt; 0,99) and sensitivity comparable to a conventional spectrophotometer. In the quantification of sunset yellow (<em>λ</em><small>_max</small> = 480 nm) in the presence of tartrazine (<em>λ</em><small>_max</small> = 430 nm), the AS sensors showed enhanced sensitivity and linearity, minimizing the spectral overlapping. Their versatility and cost-effectiveness make them ideal for real-time, portable applications. Furthermore, their compatibility with microcontrollers and capability for wireless data transmission enhance their utility across diverse analytical environments.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 48","pages":" 8427-8436"},"PeriodicalIF":2.7,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction: p-Chloranil modified carbon nanotubes paste electrode as a voltammetric sensor for the simultaneous determination of methyldopa and uric acid","authors":"Hassan Karimi-Maleh, Mohammad A. Khalilzadeh, Zahra Ranjbarha, Hadi Beitollahi, Ali A. Ensafi and Daryoush Zareyee","doi":"10.1039/D4AY90148G","DOIUrl":"https://doi.org/10.1039/D4AY90148G","url":null,"abstract":"<p >Retraction of ‘<em>p</em>-Chloranil modified carbon nanotubes paste electrode as a voltammetric sensor for the simultaneous determination of methyldopa and uric acid’ by Hassan Karimi-Maleh <em>et al.</em>, <em>Anal. Methods</em>, 2012, <strong>4</strong>, 2088–2094, https://doi.org/10.1039/C2AY05865K.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 46","pages":" 8046-8046"},"PeriodicalIF":2.7,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/ay/d4ay90148g?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142736725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent progress in gold-derived nanomaterials for tumor theranostics","authors":"Xi Deng, Lei Hu, Hui Xing, Yun Liu and Hong Yin","doi":"10.1039/D4AY01932F","DOIUrl":"10.1039/D4AY01932F","url":null,"abstract":"<p >It is widely acknowledged that gold-based materials are of significant interest in the field of biomedicine. Consequently, considerable efforts have been devoted to identifying gold nanoparticles that exhibit effective performance in tumor diagnosis and treatment. However, the underlying reasons for the enhanced efficacy of these gold-based nanomaterials in cancer therapy and diagnosis remain unclear, primarily due to the lack of an in-depth understanding of the mechanisms involved. Therefore, it is essential to summarize the progress in the field to facilitate the rational design of more efficient nanodevices. In this review, we present recent achievements drawn from the latest research to demonstrate the broad applications of gold-based materials. We begin by illustrating the mechanisms of gold-derived nanoparticles during therapeutic and diagnostic processes, including photothermal therapy, photodynamic therapy, sonodynamic therapy, photoacoustic tomography, fluorescence imaging, and X-ray computed tomography. We then summarize the advancements of gold-based nanomaterials in cancer diagnosis and treatment while also analyzing the factors contributing to their enhanced performance. Finally, we highlight key descriptors for evaluating the efficacy and strategies for designing high-performance nanomaterials. This review aims to pave the way for addressing future challenges and outlines directions for the advancement of gold-based biomedicine.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 47","pages":" 8058-8067"},"PeriodicalIF":2.7,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}