Journal of Inclusion Phenomena and Macrocyclic Chemistry最新文献

{"title":"Complexes of cationic non-symmetric porphyrin with synthetic and natural nucleic acids","authors":"Natalya Sh. Lebedeva,&nbsp;Elena S. Yurina,&nbsp;Sabir S. Guseinov,&nbsp;Sergey A. Syrbu","doi":"10.1007/s10847-023-01207-z","DOIUrl":"10.1007/s10847-023-01207-z","url":null,"abstract":"<div><p>Porphyrins, owing to their unique physicochemical properties, hold great potential as candidates for the synthesis of new materials and active pharmaceutical drugs. The introduction of functional groups into porphyrin structures enables the creation of novel compounds with finely tuned structural and optical properties, as well as complex-forming abilities. In this study, spectral and thermochemical investigations were conducted to explore the complex formation of 5-[4′-(<i>N</i>-methyl-1″,3″-benzoimidazol-2″-yl)phenyl]-10,15,20-tris-(<i>N</i>-methyl-3′-pyridyl)porphyrin triiodide with synthetic (poly[d(GC)2], poly[d(AT)2]) and natural (ssDNA, ctDNA) nucleic acids. It was observed that the porphyrin forms complexes with poly[d(AT)2] and ssDNA, localized within the major groove of the biopolymer. Additionally, the porphyrin forms multiple intercalation complexes with varying geometries when interacting with poly[d(GC)2] and ctDNA. These findings demonstrate a new potential for enhancing the selective binding of ligands with nucleic acids (NA). Moreover, the study highlights the methodological aspect that establishing the type of formed complexes based on ligands’ electronic absorption spectra, known as “fingerprints,“ may lead to incorrect conclusions.</p></div>","PeriodicalId":638,"journal":{"name":"Journal of Inclusion Phenomena and Macrocyclic Chemistry","volume":"103 11-12","pages":"429 - 440"},"PeriodicalIF":2.3,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135137271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Synthesis of functional (thia)calix[4]arene derivatives using modular azide-alkyne cycloaddition approach","authors":"Egor Makarov,&nbsp;Zarina Iskhakova,&nbsp;Vladimir Burilov,&nbsp;Svetlana Solovieva,&nbsp;Igor Antipin","doi":"10.1007/s10847-023-01202-4","DOIUrl":"10.1007/s10847-023-01202-4","url":null,"abstract":"","PeriodicalId":638,"journal":{"name":"Journal of Inclusion Phenomena and Macrocyclic Chemistry","volume":"103 9-10","pages":"355 - 368"},"PeriodicalIF":2.3,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135475809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemically controlled self-assembly behaviors of dibenzo-24-crown-8 bearing ammonium salt moiety","authors":"Xia Tian,&nbsp;Jianrong Han,&nbsp;Sheng wei Zhou,&nbsp;Yupeng Wang,&nbsp;Yuting Li,&nbsp;Chengbin Wang,&nbsp;Wei Su,&nbsp;Shouxin Liu","doi":"10.1007/s10847-023-01208-y","DOIUrl":"10.1007/s10847-023-01208-y","url":null,"abstract":"<div><p>A novel [c2] daisy chain was successfully constructed by the hermaphroditic monomer of dibenzo[24]-crown-8 (DB24C8) derivative bearing secondary ammonium salt (1) from the analysis of the solution-phase behavior of parent monomers and single-crystal X-ray analysis. ¹H NMR spectroscopy was employed to show that the crown ether moiety and the secondary ammonium salt unit underwent acid–base and alkali metal cation dependent switches. The complexation behavior of this hermaphroditic monomer in the solution was further demonstrated to exhibit the controlled photophysical behavior as a reversible luminescent switch in the presence of acids or bases. Solid morphology was determined by SEM.</p></div>","PeriodicalId":638,"journal":{"name":"Journal of Inclusion Phenomena and Macrocyclic Chemistry","volume":"103 11-12","pages":"441 - 450"},"PeriodicalIF":2.3,"publicationDate":"2023-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135773674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"β-Cyclodextrins bearing ethylene glycol chains at their primary side: their preparations and evaluation as solubilizing agents for 17-β-estradiol and nuclear magnetic resonance structural analysis of a 17-β-estradiol inclusion complex","authors":"Yoshiki Oda,&nbsp;Junki Nakagawa,&nbsp;Kaname Kasturaya,&nbsp;Takashi Yamanoi","doi":"10.1007/s10847-023-01206-0","DOIUrl":"10.1007/s10847-023-01206-0","url":null,"abstract":"<div><p>In this study, we designed and prepared two new β-cyclodextrins (<b>1</b> and <b>2</b>) bearing ethylene glycol chains to develop highly water-soluble cyclodextrins. They had excellent water solubility and could successfully dissolve 17-β-estradiol in water, which was considered a poorly soluble drug model. Additionally, the nuclear magnetic resonance structural analysis of a mixed sample of 17-β-estradiol and <b>1</b> in D₂O–H₂O suggested two different types of inclusion complexes with different 17-β-estradiol molecule orientations inside the cavity of <b>1</b>.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":638,"journal":{"name":"Journal of Inclusion Phenomena and Macrocyclic Chemistry","volume":"103 11-12","pages":"421 - 428"},"PeriodicalIF":2.3,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135809681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macroscopic supramolecular self-assembly detection based on HALCON machine vision","authors":"Yajun Zhang,&nbsp;Jiadong He,&nbsp;Fengsheng Huang,&nbsp;Yanbo Lu,&nbsp;Cheng Yu,&nbsp;Zhiming Jin","doi":"10.1007/s10847-023-01205-1","DOIUrl":"10.1007/s10847-023-01205-1","url":null,"abstract":"<div><p>Macroscopic supramolecular self-assembly (MSSA) has emerged as a new area of research in the field of supramolecular chemistry. The construction of macroscopic supramolecular structures using interfacial assembly by modifying functional groups on the surface of macromolecules and exploiting the weak interactions between surface functional groups is gaining more and more attention. With the advancement of gel technology, significant progress has been made in MSSA. However, MSSA still faces challenges such as low detection efficiency and accuracy. In this paper, a MSSA detection technique based on HALCON machine vision is designed. The technique first locates the hydrogel block (HB) by shape-based template matching and then uses machine vision techniques to detect whether the HBs are assembled. Finally, through the self-assembly judgment and detection of 500 groups of HBs, the results show that the technology can efficiently and accurately complete the MSSA detection function, which is of great significance for the development of supramolecular chemistry.</p></div>","PeriodicalId":638,"journal":{"name":"Journal of Inclusion Phenomena and Macrocyclic Chemistry","volume":"103 11-12","pages":"407 - 419"},"PeriodicalIF":2.3,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136234747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gamma-cyclodextrin functionalized silver nanoparticle-based colorimetric assay for the determination of metformin in pharmaceutical samples","authors":"Pervin Işik Bilgili,&nbsp;Saliha Esin Çelik,&nbsp;Reşat Apak","doi":"10.1007/s10847-023-01204-2","DOIUrl":"10.1007/s10847-023-01204-2","url":null,"abstract":"<div><p>Metformin hydrochloride (MET) (N,N-dimethylbiguanide) is an antidiabetic drug and widely used for treating worldwide disease, Type 2 diabetes. MET shows significant benefits for human health such as reducing high blood sugar and cholesterol/triglyceride levels, treating for polycystic ovary syndrome and having anticancer and antiaging effects. In this study, a facile colorimetric determination of metformin in drug preparations was carried out by environmentally friendly gamma-cyclodextrin (γ-CD) stabilized silver nanoparticles (CD-AgNPs). Gamma-cyclodextrin was used for the formation of AgNPs as both the metal salt − reducing and nanoparticle − stabilizing agent. As a visual optical probe, well-dispersed spherical yellow-colored CD-AgNPs (at an average particle size of 10 ± 2 nm) showing maximal surface plasmon resonance absorption at 405 nm was synthesized by one-step method. In the presence of metformin, dispersed AgNPs get aggregated, and a controlled destabilization of CD-AgNPs and core-centered growth of Ag(0) atoms (20 ± 2 nm) were observed a result of host-guest interaction between CD-AgNPs and metformin. Non-covalent hydrogen bonding between the hydroxyl groups of CD-AgNPs (in the outer cavity) and the guanidine groups of MET enables the CDs to form a host-guest inclusion complexation followed by aggregation leading to color change from yellow to orange and an increase of the absorbance at 550 nm. Inclusion complex formation was characterized by using FTIR, UV-Vis spectroscopy, DSC and STEM techniques. Under optimized conditions, the absorbance ratio at A_{550 nm}/A_{405 nm} was linearly correlated to the concentration of metformin in the range of 0.2–1.25 µM. The proposed assay showed high sensitivity with 42 nM detection limit. The method was selective toward possible interferents (potassium, carbonate, sulfate, chloride and sodium ions, urea, glucose) and also successfully applied to conventional drug samples including MET. The results obtained by proposed, reference and HPLC assays were analyzed statistically using the two-way ANOVA test to demonstrate their agreement with each other at 95% confidence level (P = 0.05, F_exp = 0.068, F_crit(table) = 6.943, F_exp &lt; F_crit(table)). MET contents (mg) of drug samples in tablet form were determined with high accuracy (REC% 97.3-100.7) and reproducibility (RSD% 1.49–2.78). It is noteworthy that the developed CD-AgNP − based colorimetric method seems to be of higher or comparable sensitivity compared to other nanoparticle − based optical assays.</p></div>","PeriodicalId":638,"journal":{"name":"Journal of Inclusion Phenomena and Macrocyclic Chemistry","volume":"103 9-10","pages":"393 - 405"},"PeriodicalIF":2.3,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135858598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly conductive MXene/Ag nanowire/UV-resin/polycarbonate flexible transparent electrode for capacitive sensors","authors":"Ho-Jung Jeong,&nbsp;Young Hyun Song,&nbsp;Hyeon Woo Kim,&nbsp;Yangkyu Park","doi":"10.1007/s10847-023-01203-3","DOIUrl":"10.1007/s10847-023-01203-3","url":null,"abstract":"<div><p>In the field of wearable electronics, MXenes have emerged as promising two-dimensional (2D) materials, exhibiting exceptional properties such as metallic conductivity, water dispersibility, thermal stability, mechanical stability, and high optical transmittance. In this study, we present a unique flexible transparent conductive electrode (FTCE) composed of MXene, Ag nanowire (AgNW), ultraviolet resin (UV-resin), and polycarbonate (PC). Our fabrication process involves a roll-to-roll process and entirely solution-based methods including UV-resin dispensing, AgNW solution coating, and FTCE dipping in an MXene solution, providing a cost-effective manufacturing approach. Notably, compared to the pure AgNW-based FTCE, the proposed FTCE incorporating an MXene concentration of 5 mg/mL showed a significant enhancement of 40% in electrical conductivity, while the FTCE with a concentration of 2 mg/mL exhibited an improved figure of merit. Furthermore, we successfully demonstrate an embedded system integrating the FTCE-based capacitive touch and proximity sensor. These achievements in optoelectronic performance signify a tremendous potential for the development of high-performance flexible devices.</p></div>","PeriodicalId":638,"journal":{"name":"Journal of Inclusion Phenomena and Macrocyclic Chemistry","volume":"104 5-6","pages":"307 - 315"},"PeriodicalIF":2.3,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134961129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A note on false Scott-test positives for uril-based macrocycles","authors":"Giovanni Batista de Santana Dias,&nbsp;Vitor Granero Lago,&nbsp;Grégoire Jean-François Demets","doi":"10.1007/s10847-023-01201-5","DOIUrl":"10.1007/s10847-023-01201-5","url":null,"abstract":"<div><p>This short note shows that the Scott test, which is widely used for the detection of cocaine by authorities, produces false-positives for the entire series of cucurbit[<i>n</i>]uril-type uril macrocycles and also for hemi-cucurbit[<i>n</i>]uril. For analogous macrocycles such as bambus[6]uril and biotin[6]uril this does not happen. This is a wake-up call to the scientific community and international authorities.</p></div>","PeriodicalId":638,"journal":{"name":"Journal of Inclusion Phenomena and Macrocyclic Chemistry","volume":"103 11-12","pages":"451 - 453"},"PeriodicalIF":2.3,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41875711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial and follow-up evaluations on cerebrospinal fluid involvement by hematologic malignancy.","authors":"Nouran Momen, Joseph Tario, Kai Fu, You-Wen Qian","doi":"10.1007/s12308-023-00550-x","DOIUrl":"10.1007/s12308-023-00550-x","url":null,"abstract":"<p><p>Central nervous system (CNS) involvement is a serious complication in hematologic malignancy, and early detection and management of CNS involvement in these cases significantly impact the prognosis. Currently, there is no consensus on the use of multiparametric flow cytometry (MFC) and conventional cytology (CC) testing for initial and follow-up cerebrospinal fluid (CSF) specimens to diagnose CNS involvement by hematologic malignancy. In our institution, after initial MFC and CC, two subsequent negative MFCs are required before discontinuing MFC. The aim of this study is to evaluate the outcome of this approach. CSF cytology and MFC reports were retrieved from Laboratory Information System, and data was reviewed. Between January 2020 and December 2021, 1789 CSF samples from 280 patients were submitted for CSF analysis. For those 517 CSF samples tested by both MFC and CC, 97 cases tested positive by both MFC and CC with 95% concordance. Eighteen cases were MFC + /CC - and 7 were MFC - /CC + . Thirty-six cases had initially positive MFCs followed by more than one MFC evaluation. Among those 36 cases, 22 cases (61.1%) converted to negative after the second follow-up sample, 9 cases (25%) were continuously positive for at least three samples, and 5 cases (13.9%) exhibited negative to positive conversion. Compared to negative CSF cases, positive CSFs had higher total nucleated cell count and higher total protein levels while red blood cells, glucose, and lactate dehydrogenase levels remained at comparable levels. The concordance between MFC and CC was excellent. The high incidence of positive MFCs on two or more follow-up samples and the high frequency of negative MFC to positive conversion indicate the necessity of repeated negative MFCs before discontinuing MFC. The fact that more than half of the positive cases converted to negative after the second CSF specimen and most follow-up positive cases can be detected by CC alone suggests it is adequate to use CC alone for follow-up CSF study after two consecutive negative MFCs.</p>","PeriodicalId":638,"journal":{"name":"Journal of Inclusion Phenomena and Macrocyclic Chemistry","volume":"29 1","pages":"131-140"},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72470256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of functional (thia)calix[4]arene derivatives using modular azide-alkyne cycloaddition approach","authors":"Egor Makarov,&nbsp;Zarina Iskhakova,&nbsp;Vladimir Burilov,&nbsp;Svetlana Solovieva,&nbsp;Igor Antipin","doi":"10.1007/s10847-023-01200-6","DOIUrl":"10.1007/s10847-023-01200-6","url":null,"abstract":"<div><p>Today, the modification of the organic molecules using the copper-catalyzed azide-alkyne cycloaddition reaction (CuAAC) is of great interest, as evidenced by the Nobel Prize in Chemistry awarded in 2022 to the founder of “click” chemistry. Supramolecular chemistry, in turn, is one of the actively developing branches of modern science. Using the CuAAC approach is a very convenient method to obtain new macrocyclic structures of interest. This review focuses on the use of the modular “click”-chemistry approach for the synthesis of various triazole derivatives of thiacalix[4]arenes and calix[4]arenes as well as general routes for the synthesis of their precursors (azides and alkynes). Examples of some functional systems based on triazole-containing macrocycles, such as chemosensors, multicalixarenes, amphiphilic calixarenes as well as examples of the use of triazole calixarenes for bioapplications are described.</p></div>","PeriodicalId":638,"journal":{"name":"Journal of Inclusion Phenomena and Macrocyclic Chemistry","volume":"103 9-10","pages":"319 - 353"},"PeriodicalIF":2.3,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44512406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}