2009 2nd International Conference on Biomedical Engineering and Informatics最新文献_第8页

Physical Properties of LYSO Scintillator for NN-PET Detectors 用于NN-PET探测器的LYSO闪烁体的物理性质

2009 2nd International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305107

Junwei Du, Yonggang Wang, Lijun Zhang, Zhong-qiu Zhou, Zizhong Xu, Xiaolian Wang

{"title":"Physical Properties of LYSO Scintillator for NN-PET Detectors","authors":"Junwei Du, Yonggang Wang, Lijun Zhang, Zhong-qiu Zhou, Zizhong Xu, Xiaolian Wang","doi":"10.1109/BMEI.2009.5305107","DOIUrl":"https://doi.org/10.1109/BMEI.2009.5305107","url":null,"abstract":"Cerium doped lutetium oxyorthosilicate scintillators, such as LYSO, which possess high stopping power, high light output and fast decay time, are promising candidates for use in positron emission tomography. In this paper, the luminescence and nuclear spectroscopic properties of two LYSO samples, used in the NN-PET detectors, are studied. UV-excited emission spectra show that maximum emission spectral values are within the range of 400-425nm, which is well compatible with spectral response of PMT H7546B. The decay time, energy resolution, light output and energy spectra related to coincidence time window were investigated. The decay times of the two LYSO samples are 34.16±1.43ns, 34.26±1.95ns, respectively. The energy resolution and the light output, relative to NaI(Tl), are 10.25%±0.06%, 10.17%±0.10% and 75.3±5.7, 76.1±5.8 respectively when detected with PMT XP2262B. The energy spectra change obviously with coincidence time window and coincidence energy resolution is 14% when obtained using coincidence detector based on LYSO and H7546B. Keywords-LYSO;Decay time;Energy resolution;Light output; Energy spectra;","PeriodicalId":6389,"journal":{"name":"2009 2nd International Conference on Biomedical Engineering and Informatics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72603665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Epithelial Tissue Abnormity Analysis Based on Single Backscattering Polarimetric Spectrum 基于单次后向散射偏振光谱的上皮组织异常分析

2009 2nd International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305339

Yongqiang Zhao, PeiFeng Wei

引用次数: 0

Prediction of Membrane Protein Types by Using Support Vector Machine Based on Composite Vector 基于复合向量的支持向量机预测膜蛋白类型

2009 2nd International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305127

Ting Wang, Xiuzhen Hu

引用次数: 0

The Implementation and Application of the Microarray Preprocessing Generalized PDNN Model 微阵列预处理广义PDNN模型的实现与应用

2009 2nd International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5302030

Wei Wei, Lin Wan, M. Qian, Minghua Deng

{"title":"The Implementation and Application of the Microarray Preprocessing Generalized PDNN Model","authors":"Wei Wei, Lin Wan, M. Qian, Minghua Deng","doi":"10.1109/BMEI.2009.5302030","DOIUrl":"https://doi.org/10.1109/BMEI.2009.5302030","url":null,"abstract":"The preprocessing of the Microarray data is a hot topic in the bioinformatics research. The key point of a successful preprocessing method is to remove the noise of nonspecific binding and to keep the information of specific binding as much as possible. One way to solve these problems is to understand the principle of the binding between probes and target sequences, and to distinguish specific binding from nonspecific binding correctly. In this paper, we introduce MM probe intensities into position dependent nearest neighbor (PDNN) model, which contain much information of nonspecific binding.We use two-step model to estimate the parameters,which can simplify the computation. Based on the Wilcoxon rank test, we can determine whether a gene is present, with which we can obtain the training data set for the specific binding and non specific binding parameters. We also apply our model to gene expression data (HGU133plus2.0 and HGU133A) . We find that all these improvements increase the precision and stability, and show better result compared to the other four methods( Mas5.0, dChip, RMA and PDNN ).","PeriodicalId":6389,"journal":{"name":"2009 2nd International Conference on Biomedical Engineering and Informatics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84587542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Experimental Study on Ocular Rigidity of Rabbit In Vivo 兔眼强直的体内实验研究

2009 2nd International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305808

Weiyi Chen, Chunsheng Liu, Xiaojun Wang, Yanjun Li, Xiao-na Li, Lei Ma

引用次数: 2

Analysis of Synonymous Codon Usage in the UL26.5 Gene of Duck Enteritis Virus 鸭肠炎病毒UL26.5基因同义密码子使用分析

2009 2nd International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305044

Yao Zhang, A. Cheng, Mingshu Wang, Dekang Zhu, R. Jia, Fei Liu, Xiaoyue Chen

{"title":"Analysis of Synonymous Codon Usage in the UL26.5 Gene of Duck Enteritis Virus","authors":"Yao Zhang, A. Cheng, Mingshu Wang, Dekang Zhu, R. Jia, Fei Liu, Xiaoyue Chen","doi":"10.1109/BMEI.2009.5305044","DOIUrl":"https://doi.org/10.1109/BMEI.2009.5305044","url":null,"abstract":"The analysis on codon usage bias of UL26.5 gene of duck enteritis virus (DEV) may provide a basis for understanding the evolution and pathogenesis of DEV and for selecting appropriate host expression systems to improve the expression of target genes in vivo and in vitro. In this study, the synonymous codon usage in the UL26.5 gene of DEV and 27 reference herpesviruses have been investigated . The results reveals that the synonymous codons with A and T at the third codon positon have widely usage in the codon of UL26.5 gene of DEV. G + C compositional constraint is the main factor that determines the codon usage bias in UL26.5 gene. The phylogentic analysis suggested that DEV was evolutionarily closer to fowl herpesviruses which further clustered into Alphaherpesvirinae. There were both 21 codons showing distinct usage differences between DEV with Escherichia coli and yeast, 25 between DEV and Homo sapiens, 26 between DEV and adenovirus. Therefore the yeast and E. coli expression system may be suitable for the expression of DEV UL26.5 gene if some codons could be optimized.","PeriodicalId":6389,"journal":{"name":"2009 2nd International Conference on Biomedical Engineering and Informatics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85442106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Analytical System Based on Raman Spectroscopy in Melamine Detection 基于拉曼光谱的三聚氰胺检测分析系统

2009 2nd International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305231

Hai-ling Xiao, Ru-gang Zhong, D. Zheng

{"title":"Analytical System Based on Raman Spectroscopy in Melamine Detection","authors":"Hai-ling Xiao, Ru-gang Zhong, D. Zheng","doi":"10.1109/BMEI.2009.5305231","DOIUrl":"https://doi.org/10.1109/BMEI.2009.5305231","url":null,"abstract":"People have paid close attention to melamine by Sanlu Event. Melamine, a widely used as an organic chemical in industry, was added in milk to increase the protein content. Obviously, traditional kjeldahl hasn't suitable to detect real protein content. Focusing on the milk with melamine in market, a rapid and easy method is necessary to meet the needs to detect melamine from the milk. In this study, the analytical system was developed by surface enhanced Raman spectrum (SERS) and portable Raman spectrometer, which had fast detecting and alarming functions. Firstly, Qualitative analysis method for detecting melamine in milk was found. And the peak 709cm -1 was used as the essential peak for qualitative analysis method. On the basis of that, quantitative method was further defined. The concentration of melamine in milk vs Ratio of 709cm -1 /1026cm -1 showed a good linear relationship when the standard concentration of melamine in milk within 3ppm to 10ppm. Detective limit of this method was 1ppm, and the quantization limit was 3ppm. Recovery was in 86% to 106% and satisfied the request of GB/T22388-2008 (80%- 110%). Analytical system was established for determination melamine in milk. Multiple functions were contained in this system. Detecting and result were completed rapidly by used analytical system on condition that the concentration of melamine within 3ppm to 10ppm. The red signal was displaying at concentration above 3ppm, and the green signal was giving at concentration below 3ppm.","PeriodicalId":6389,"journal":{"name":"2009 2nd International Conference on Biomedical Engineering and Informatics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79751197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Novel k'-Means Algorithm for Clustering Analysis 一种新的k′-均值聚类分析算法

2009 2nd International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5304816

Chonglun Fang, Jinwen Ma

引用次数: 9

An Integrated Cross-Database Search System for microRNA microRNA的集成跨数据库检索系统

2009 2nd International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305536

Yijun Chen

引用次数: 2

A Hybrid System for Prediction of Protein Subcellular Localization 预测蛋白质亚细胞定位的杂交系统

2009 2nd International Conference on Biomedical Engineering and Informatics Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305500

Shu-Bo Zhang, J. Lai

引用次数: 0