国际生物医学工程杂志最新文献

{"title":"Ureteroscopy under conscious sedation: A proof-of-concept study.","authors":"Kunal Jain, Ruben Blachman-Braun, Esha Jain, Amanda Eng, Brian Peters, Premal Patel","doi":"10.5489/cuaj.7750","DOIUrl":"10.5489/cuaj.7750","url":null,"abstract":"<p><strong>Introduction: </strong>Ureteroscopy (URS) is commonly performed under general anesthesia (GA) to maximize patient tolerability and minimize surgical complications; however, given the improvements in endoscopic technology and risks associated with GA, alternate forms of anesthesia have been postulated. We aimed to evaluate the outcomes of URS under conscious sedation.</p><p><strong>Methods: </strong>We completed a retrospective cohort study from November 2019 to June 2020 at a tertiary-level hospital. All URSs that were performed under urologist-directed conscious sedation were included. Our primary outcome was the ability to complete URS, defined as success rate. Secondary outcomes included: stone-free rate, intraoperative complication rate, hospital admission rate, and sedation requirement. Univariate- and multivariate-adjusted logistic regression analyses were employed.</p><p><strong>Results: </strong>Ninety-nine URSs were included. Most (73/99, 73.7%) were performed for urolithiasis. The overall success rate was 83.8% (83/99), with 81.0% (34/42) intra-renal and 70.0% (16/23) proximal ureter success rates. The stone-free rate was 80.8% (59/73). No intraoperative complications nor hospital admissions were reported. The mean amount of sedation required was 3 mg (interquartile range [IQR] 2-4] of midazolam and 100 μg (100-150) of fentanyl. On multivariate analysis, midazolam was significantly associated with increased success (odds ratio 2.496, 95% confidence interval 1.057-5.892, p=0.037).</p><p><strong>Conclusions: </strong>We have shown that proximal and intrarenal URS under conscious sedation is safe and effective. We were limited by our lack of followup, small sample size, selection bias to chose healthy patients, and lack of patient tolerability data. Patients and healthcare systems may benefit from implementing this innovation more broadly.</p>","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":"41 1","pages":"E461-E467"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75664203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study on Assessment of Depression, Anxiety and Stress among South Indian Population During the COVID-19 Pandemic","authors":"Sreeja Nyayakar","doi":"10.37628/IJBME.V6I2.748","DOIUrl":"https://doi.org/10.37628/IJBME.V6I2.748","url":null,"abstract":"","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43191266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Antiviral Activities of Glycyrrhizin","authors":"Changchao Huan, Chun-qiao Chen, Xu Weiyin, Guo Tingting, Haochun Pan, Song Gao","doi":"10.11648/J.IJBECS.20200604.11","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20200604.11","url":null,"abstract":"Licorice has been a common Chinese medicine for thousands of years, which has good medicinal value and nutritional value. Is widely apply to traditional Chinese medicine. Many studies have shown that licorice contains more than 20 triterpenoids and nearly 300 flavonoids. According to the literature, licorice has many activities such as antibacterial, antiviral, antioxidant, and anticancer. It not only directly inactivates the virus, but also inhibits its adsorption. However, glycyrrhizin, glycyrrhetinic acid, glycyrrhiza polysaccharide and glycyrrhiza flavonoids are the main components of licorice which possess antiviral and antimicrobial activities. Among them, glycyrrhizin has many pharmacological activities, such as antiviral, anti-inflammatory, anti-tumor, antibacterial and many other activities. This paper provides a summary of antiviral activities of glycyrrhizin. This active ingredients and possible mechanisms are summarized in detail. The results showed that glycyrrhizin was widely used in antiviral field, but its material basis and mechanism of action were not perfect and unified. A large number of literatures about glycyrrhizin anti-virus were reviewed and analyzed, and it was suggested that more different ways should be adopted to study it, so as to provide a broader theoretical basis for developing new antivirus drugs of glycyrrhizin. It is hoped that this review will be helpful to further study the potential therapeutic effect of glycyrrhizin as an antiviral drug.","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":"6 1","pages":"68"},"PeriodicalIF":0.0,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48105420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Clinical Teaching of Fourth Year Anaesthesia Students: The Case of Wolaita Sodo University","authors":"M. S. Obsa, Getahun Molla Shanka, Getahun Dendir Wolde, Wolde Facha Faltamo","doi":"10.11648/J.IJBECS.20200603.11","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20200603.11","url":null,"abstract":"Background: Anesthesia programs prepare students through course work that develops knowledge and skills in anesthesia practice as well as in organizational and leadership skills, and courses are strongly related to theoretical and clinical teaching. In health science professions, clinical or practical experience is necessary to develop knowledge and skills acquired theoretically. For this reason, both theoretical and clinical components of education are included in health science educational programmes. The purpose of the theoretical component is to provide students the opportunity to learn principles and concepts relevant for professional performance. Objective: To improve the practical teaching of fourth-year anesthesia students, CHSM, WSU from March 10-April 10, 2019. Methods and Materials: A cross-sectional study design was employed. Training was given for data collectors and supervisors. Regular supervision and follow-up were performed. Questionnaires was used as data collection tools. Conclusion: Anesthesia students’ clinical experiences are an important element of the profession as well as clinical teaching, which is the cornerstone of education.","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":"6 1","pages":"55"},"PeriodicalIF":0.0,"publicationDate":"2020-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41531668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Depressive Symptoms with Iron Management in Patients on Maintenance Hemodialysis: A Cross-sectional Study","authors":"Yoshihiro Tsuji, Naoki Suzuki, Yasumasa Hitomi, Y. Mizuno-Matsumoto, T. Tokoro, M. Nishimura","doi":"10.11648/J.IJBECS.20200602.14","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20200602.14","url":null,"abstract":"Background: Iron status has a critical role in depressive symptoms, but evaluation of depressive symptoms associated with iron metabolism is not usually included as a clinical parameter in hemodialysis (HD) patients. We aimed to assess the correlations between depressive symptoms and clinical, demographic, and laboratory variables including iron metabolism. Methods: One hundred and thirty-eight HD patients were evaluated in this study. The Beck Depression Inventory Second Edition (BDI−II) was used to quantify levels of depressive symptoms. BDI−II scores ≥ 14 were defined as depressive symptoms. Mean age, duration of HD, haemoglobin levels, serum ferritin levels, serum iron levels, transferrin saturation (TSAT), total iron binding capacity, serum albumin levels, and C-reactive protein were included in the model. Patients were categorized into four groups according to serum ferritin levels and TSAT. Backward stepwise logistic regression analysis was performed and odds ratios (ORs) and 95% confidence intervals derived. Results: Depressive symptoms were significantly associated with increased serum ferritin levels (OR, 1.010; p=0.0008). Compared with group 1 (ferritin <100 ng/dL, TSAT ≥20%) as reference, ORs for depressive symptoms were significantly increased in group 4 (ferritin ≥100 ng/dL, TSAT < 20%) (OR, 6.419; p=0.0073). Conclusion: Higher serum ferritin levels and decreased iron utilization efficiency were found to be involved in depressive symptoms among patients undergoing HD. Understanding the pathophysiology of depressive symptoms could provide insights into the design of clinical iron management in HD patients.","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64791950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hearing Aids of the Future: A Simulation Study","authors":"Akshay Mendhakar, Sneha Poochiriyan, Devi Neelamegarajan, Renuka Chandrakanth","doi":"10.37628/IJBME.V6I1.649","DOIUrl":"https://doi.org/10.37628/IJBME.V6I1.649","url":null,"abstract":"Modern hearing aids are a derivative of bulky systems. Though the adaptability and effectiveness of hearing aid plays a crucial role, the current hearing aids fail to account these factors in different listening situations due to the limitations in their signal processing abilities. To tackle this issue, the current paper presents a simulation study which highlights the use of machine learning for dynamically programming hearing aids for different listening situations. To represent these conditions, a Deep Neural Network (DNN) was built and real time inputs of six different listening situations were taken. The dynamical programmability of the DNN was compared with that of a classic fit hearing aid. The final results were used to understand the impact of DNN on speech processing abilities of a single fit hearing aid. Keywords : adaptive, hearing aid, listening condition, machine learning, neural network Cite this Article: Akshay Mendhakar, Sneha K C, Devi N, Renuka C. Hearing Aids of the Future: A Simulation Study. International Journal of Biomedical Engineering . 2020; 6(1): 18–23p.","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":"6 1","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44204325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between the Distributions of Mean Corpuscular Hemoglobin and Red Blood Cell, and Mortality in a 3-Year Retrospective Study of Hemodialysis Patients","authors":"Yoshihiro Tsuji, Yasumasa Hitomi, Naoki Suzuki, Y. Mizuno-Matsumoto, T. Tokoro, M. Nishimura","doi":"10.11648/J.IJBECS.20200602.13","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20200602.13","url":null,"abstract":"Introduction: A red blood cell (RBC) concentration of 300 to 350×104/μL and mean corpuscular hemoglobin (MCH) concentration of 30 to 35 pg have been proposed as management target values from the relationship of Hb=RBC×MCH to control anemia, wherein Hb levels should not exceed 12 g/dL. In contrast, even in patients whose Hb levels are maintained at 10 to 12 g/dL, Hb levels are widely distributed when divided into RBC and MCH. Objective: We examined the prognosis in the distribution of MCH and RBC. Methods: Patients were classified into two groups based on MCH and RBC values, wherein patients with MCH≥30 pg but 350×104/μL (Group II, n=217). Associations between all-cause mortality and the distributions of MCH and RBC as well as the iron profiles of these two groups were assessed by Kaplan-Meier curves and Cox proportional hazards regression model, respectively. Results: Patients with MCH 350×104/μL (Group II, n=217) had an increased long-term risk of death and a higher rate of iron deficiency than patients with MCH≥30 pg but<35 pg and RBC≤350×104/μL (Group I, n=177). Conclusions: The management goal for renal anemia would be to control MCH within the range of 30−35 pg and RBC within the range of 300−350×104/μL, and to avoid absolute iron deficiency.","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":"6 1","pages":"41"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46736730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational Stress and Associated Factors among Nurses working in Public Hospitals of Arsi Zone, Oromia Regional State, Central Ethiopia, 2018","authors":"B. Hailu, Yohannes Ejigu, Y. Siraneh","doi":"10.11648/J.IJBECS.20200602.11","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20200602.11","url":null,"abstract":"Nursing, by its nature, is an occupation subject to a high degree of stress. This profession involves working with people who are themselves suffering a considerable degree of stress. Occupational stress compromised quality of service delivery and also leads as employees’ burnout, turnover and absenteeism. The Objective of the study is to determine the level of occupational stress and associated factors among nurses. The study employed facility based cross sectional study was conducted from August 13 –September 02, 2018. All nurses who served at least for 6 months in Arsi zone public hospitals were asked using self-administered structured questionnaire. The collected data was checked manually, edited, coded and entered into Epi-data version 3.1 and finally it was exported in to statistical package for social science version 24 for cleaning and analysis. Descriptive statistics were used to estimate frequency percent and mean. Dependent variables (occupational stress) were computed based on the respondents having average score of mean and above in expanded nursing stress scale. Then, associations between independent and dependent variables were analyzed first using bivariate binary logistic regression. Variables that had p<0.25 on bivariate binary logistic regression were entered into multivariable binary logistic regression and adjusted odds ratio (AOR) with 95% CI were reported. The study finding showed that 202 (53%) with (95% CI: 48.2-58.1) of nurses were occupationally stressful. Factors significantly associated with occupational stress among nurses were sex of respondents (female: AOR=2.37, 95% CI: 1.41, 3.97), marital status (ever married: AOR=2.49, 95% CI: 1.35, 4.60), Role ambiguity (nurses who had Role ambiguity: AOR=3.01, 95% CI: 1.79, 5.05) and working hours. (≥8hrs hours per day: AOR=2.85, 95% CI: 1.10, 7.36). In this study, more than half of nurses had occupational stress, Thus, Arsi zone public hospitals collaborative with concerned stakeholders to design stress reduction program for tackling occupational stress among nurses.","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":"6 1","pages":"17"},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64791875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Improved Urostomy Pouch in Collection of Seepage from Nephrostomy Tube Entry After Percutaneous Nephrolithotomy","authors":"L. Lan, Guo Xiaoxia","doi":"10.11648/J.IJBECS.20200601.13","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20200601.13","url":null,"abstract":"Objective: We attempt to explore the effect of improved urostomy pouch on collecting the seepage from the entry of the nephrostomy tube after percutaneous nephrolithotomy. Methods: We selected 106 patients who underwent percutaneous nephrolithotomy and had indwelling nephrostomy tube with abnormal increase in seepage from the nephrostomy tube entry. Random number table was used to averagely divide them into observation group (53) and control group (53). For the observation group, we used improved urostomy pouches to collect seepage from the nephrostomy tube entry while for the control group, we dealt with the seepage through changing dressings following surgical routine. After that, we compared occurrence of dermatitis around the stoma, discomfort of stoma, stoma care cost, medical staff’s satisfaction with collection of seepage, frequency of changing dressings for stoma and material expenditure, etc. between the two groups. Results: occurrence of dermatitis around the stoma, discomfort of stoma and stoma care cost in observation group were lower than those in control group with a significant difference (P=0.000). Besides, medical staff’s satisfaction with collection of seepage in observation group was higher than that in control group with a significant difference (P=0.000). Frequency of caring for the stoma expenditure of dressings in the observation group were lower than those in the control group also with a significant difference (P=0.000). Conclusions: Improved urostomy pouches in collection of seepage from the stoma after PCNL can not only ensure the leakproofness of the urinary system and the function of nephrostomy tube but also reduce the occurrence of stoma infection to improve comfort of patients and accuracy of measurement of seepage, and reduce workload of medical staff. What’s more, the improved urostomy pouches help reduce the cost of changing dressings for patients and cost of materials of the department, and thus is worth application in collection of seepage from other drainage tubes.","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":"6 1","pages":"12"},"PeriodicalIF":0.0,"publicationDate":"2020-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45721912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing Care Practices at Jimma University Medical Center: A Retrospective Cross - Sectional Study in Ethiopia","authors":"G. Abdissa, Daniel Geleta, Hiwot Berhanu, Birtukan Edilu","doi":"10.11648/J.IJBECS.20200601.12","DOIUrl":"https://doi.org/10.11648/J.IJBECS.20200601.12","url":null,"abstract":"Nursing care is the gathering of information and prioritizing interventions before providing an appropriate cares using a specified assessment format to intervene the most common problems in Hospitals. Most of the nursing care activities were left undone or poorly assessed in Europe with further disrespect & abuse of women during institutional childbirth services in low-middle-income countries including Ethiopia. The current study focused to determine the status of nursing care practices in the obstetric ward of Jimma University medical center. Wherefore, a retrospective cross-sectional study was conducted from April 16, 2019 to May 15, 2019 with documentary analysis of 344 randomly selected medical records. A semi-structured and pretested questionnaire containing 16 items of nursing diagnoses were used to collect data, which was then analyzed by SPSS version 20 under formal consent of participants. During the process of management, frequencies & percentages were calculated and used to describe the data by tables & figures for ranking among the identified nursing cares. A total of 344 records were reviewed and analyzed by the study making 100% review rate. The study revealed all the nursing cares indicated in the domains were provided to labouring mothers with variable degrees. The most prominent nursing cares in the ward were recognized to be cares related to nausea (95.9%), fatigue (95.1%), acute pain relieve related to uterine contractions (94.8%), avoidance of imbalance nutrition due to poor intake (38.1%), bathing/toileting self-care deficit related to pain (27.6%) and constipation due hemorrhoids (24.4%). The remaining elements were practiced rarely. The care practice of labouring mothers in the study unit was not comprehensive. Therefore, the researchers recommend a compressive care approach as much as possible to the study unit and further study on the determinants of variation among the care domains.","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":"6 1","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2020-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44886321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}