甘草酸的抗病毒活性研究

Changchao Huan, Chun-qiao Chen, Xu Weiyin, Guo Tingting, Haochun Pan, Song Gao
{"title":"甘草酸的抗病毒活性研究","authors":"Changchao Huan, Chun-qiao Chen, Xu Weiyin, Guo Tingting, Haochun Pan, Song Gao","doi":"10.11648/J.IJBECS.20200604.11","DOIUrl":null,"url":null,"abstract":"Licorice has been a common Chinese medicine for thousands of years, which has good medicinal value and nutritional value. Is widely apply to traditional Chinese medicine. Many studies have shown that licorice contains more than 20 triterpenoids and nearly 300 flavonoids. According to the literature, licorice has many activities such as antibacterial, antiviral, antioxidant, and anticancer. It not only directly inactivates the virus, but also inhibits its adsorption. However, glycyrrhizin, glycyrrhetinic acid, glycyrrhiza polysaccharide and glycyrrhiza flavonoids are the main components of licorice which possess antiviral and antimicrobial activities. Among them, glycyrrhizin has many pharmacological activities, such as antiviral, anti-inflammatory, anti-tumor, antibacterial and many other activities. This paper provides a summary of antiviral activities of glycyrrhizin. This active ingredients and possible mechanisms are summarized in detail. The results showed that glycyrrhizin was widely used in antiviral field, but its material basis and mechanism of action were not perfect and unified. A large number of literatures about glycyrrhizin anti-virus were reviewed and analyzed, and it was suggested that more different ways should be adopted to study it, so as to provide a broader theoretical basis for developing new antivirus drugs of glycyrrhizin. It is hoped that this review will be helpful to further study the potential therapeutic effect of glycyrrhizin as an antiviral drug.","PeriodicalId":61751,"journal":{"name":"国际生物医学工程杂志","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Study on Antiviral Activities of Glycyrrhizin\",\"authors\":\"Changchao Huan, Chun-qiao Chen, Xu Weiyin, Guo Tingting, Haochun Pan, Song Gao\",\"doi\":\"10.11648/J.IJBECS.20200604.11\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Licorice has been a common Chinese medicine for thousands of years, which has good medicinal value and nutritional value. Is widely apply to traditional Chinese medicine. Many studies have shown that licorice contains more than 20 triterpenoids and nearly 300 flavonoids. According to the literature, licorice has many activities such as antibacterial, antiviral, antioxidant, and anticancer. It not only directly inactivates the virus, but also inhibits its adsorption. However, glycyrrhizin, glycyrrhetinic acid, glycyrrhiza polysaccharide and glycyrrhiza flavonoids are the main components of licorice which possess antiviral and antimicrobial activities. Among them, glycyrrhizin has many pharmacological activities, such as antiviral, anti-inflammatory, anti-tumor, antibacterial and many other activities. This paper provides a summary of antiviral activities of glycyrrhizin. This active ingredients and possible mechanisms are summarized in detail. The results showed that glycyrrhizin was widely used in antiviral field, but its material basis and mechanism of action were not perfect and unified. A large number of literatures about glycyrrhizin anti-virus were reviewed and analyzed, and it was suggested that more different ways should be adopted to study it, so as to provide a broader theoretical basis for developing new antivirus drugs of glycyrrhizin. It is hoped that this review will be helpful to further study the potential therapeutic effect of glycyrrhizin as an antiviral drug.\",\"PeriodicalId\":61751,\"journal\":{\"name\":\"国际生物医学工程杂志\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-11-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"国际生物医学工程杂志\",\"FirstCategoryId\":\"1087\",\"ListUrlMain\":\"https://doi.org/10.11648/J.IJBECS.20200604.11\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"国际生物医学工程杂志","FirstCategoryId":"1087","ListUrlMain":"https://doi.org/10.11648/J.IJBECS.20200604.11","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3

摘要

甘草作为一种常见的中药已有数千年的历史,具有良好的药用价值和营养价值。广泛应用于中医。许多研究表明,甘草中含有20多种三萜类化合物和近300种黄酮类化合物。据文献记载,甘草具有抗菌、抗病毒、抗氧化、抗癌等多种活性。它不仅能直接灭活病毒,还能抑制病毒的吸附。然而,甘草酸、甘草次酸、甘草多糖和甘草黄酮是甘草的主要成分,具有抗病毒和抗菌活性。其中,甘草甜素具有抗病毒、抗炎、抗肿瘤、抗菌等多种药理活性。本文综述了甘草甜素的抗病毒活性。对这些活性成分及其可能的作用机制进行了详细的综述。结果表明,甘草甜素在抗病毒领域有着广泛的应用,但其物质基础和作用机制尚不完善和统一。对大量有关甘草甜素抗病毒的文献进行了综述和分析,认为应采用更多不同的方法对其进行研究,为开发新的甘草甜素类抗病毒药物提供更广阔的理论基础。希望这篇综述将有助于进一步研究甘草甜素作为一种抗病毒药物的潜在治疗作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Study on Antiviral Activities of Glycyrrhizin
Licorice has been a common Chinese medicine for thousands of years, which has good medicinal value and nutritional value. Is widely apply to traditional Chinese medicine. Many studies have shown that licorice contains more than 20 triterpenoids and nearly 300 flavonoids. According to the literature, licorice has many activities such as antibacterial, antiviral, antioxidant, and anticancer. It not only directly inactivates the virus, but also inhibits its adsorption. However, glycyrrhizin, glycyrrhetinic acid, glycyrrhiza polysaccharide and glycyrrhiza flavonoids are the main components of licorice which possess antiviral and antimicrobial activities. Among them, glycyrrhizin has many pharmacological activities, such as antiviral, anti-inflammatory, anti-tumor, antibacterial and many other activities. This paper provides a summary of antiviral activities of glycyrrhizin. This active ingredients and possible mechanisms are summarized in detail. The results showed that glycyrrhizin was widely used in antiviral field, but its material basis and mechanism of action were not perfect and unified. A large number of literatures about glycyrrhizin anti-virus were reviewed and analyzed, and it was suggested that more different ways should be adopted to study it, so as to provide a broader theoretical basis for developing new antivirus drugs of glycyrrhizin. It is hoped that this review will be helpful to further study the potential therapeutic effect of glycyrrhizin as an antiviral drug.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
1974
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信