Journal of Analytical Chemistry最新文献_第7页

Determination of Pesticide Residues in Wheat Grains by GC–MS/MS after Their Extraction by a Modified QuEChERS Method Using Hyper-Cross-Linked Polystyrene at the Purification Stage 超交联聚苯乙烯改性QuEChERS法提取小麦籽粒中农药残留的GC-MS /MS测定

IF 1.1 4区化学

Journal of Analytical Chemistry Pub Date : 2025-07-05 DOI: 10.1134/S1061934825700418

E. S. Osinova, A. O. Melekhin, D. P. Bulkatov, V. V. Tishchenko, I. A. Khalyavin

{"title":"Determination of Pesticide Residues in Wheat Grains by GC–MS/MS after Their Extraction by a Modified QuEChERS Method Using Hyper-Cross-Linked Polystyrene at the Purification Stage","authors":"E. S. Osinova, A. O. Melekhin, D. P. Bulkatov, V. V. Tishchenko, I. A. Khalyavin","doi":"10.1134/S1061934825700418","DOIUrl":"10.1134/S1061934825700418","url":null,"abstract":"Hyper-crosslinked polystyrene is proposed for the purification of extracts after sample preparation by the QuEChERS method using multicomponent dispersive solid-phase extraction in the determination of residues of 19 pesticides in wheat grains by gas chromatography with tandem mass spectrometry detection. Sample preparation included extraction with water and acetonitrile followed by the purification of the extracts using hyper-crosslinked polystyrene. The method ensures the quantitative isolation of pesticides (recovery range from 66 to 100%). Pesticides are identified by selected transitions in the multiple reaction monitoring mode. The determination is performed using the matrix calibration method, the limits of detection and quantification are 0.03–0.3 and 0.1–1.0 μg/kg, respectively. An analysis of contaminated wheat samples show that the results satisfactorily coincide with the data obtained by the classical QuEChERS method in determining pesticide residues in agricultural products.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"80 6","pages":"1068 - 1076"},"PeriodicalIF":1.1,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145162341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound-Assisted Deep Eutectic Solvent-Based Liquid-Liquid Microextraction for Pre-Concentration and Determination of Trace Amounts of Cobalt in Real Samples 超声辅助深共晶溶剂-液-液微萃取预富集及测定样品中痕量钴

IF 1.1 4区化学

Journal of Analytical Chemistry Pub Date : 2025-07-05 DOI: 10.1134/S1061934825700339

Ali Mohammadzadeh, Atefeh Ranjbar

引用次数: 0

Application of the H-Point Standard Addition Method for Simultaneous Spectrophotometric Determination of Isoniazid and Mesalazine via Charge-Transfer Complex Formation Reactions h点标准加入法在电荷转移络合物形成反应中同时光度测定异烟肼和美沙拉嗪中的应用

IF 1.1 4区化学

Journal of Analytical Chemistry Pub Date : 2025-07-05 DOI: 10.1134/S1061934825700340

Theia’a N. Al-Sabha, Mohammed S. El-Enizzi

引用次数: 0

Chromatography–Mass Spectrometry of Trinitrotoluene Isomers in the Negative Ionization Mode Under Resonance Electron Capture 共振电子俘获下负电离模式下三硝基甲苯异构体的色谱-质谱分析

IF 1.1 4区化学

Journal of Analytical Chemistry Pub Date : 2025-07-05 DOI: 10.1134/S1061934825700431

R. V. Khatymov, A. G. Terentyev, A. V. Dudkin, A. V. Dyachkov, M. D. Krykin

{"title":"Chromatography–Mass Spectrometry of Trinitrotoluene Isomers in the Negative Ionization Mode Under Resonance Electron Capture","authors":"R. V. Khatymov, A. G. Terentyev, A. V. Dudkin, A. V. Dyachkov, M. D. Krykin","doi":"10.1134/S1061934825700431","DOIUrl":"10.1134/S1061934825700431","url":null,"abstract":"Processes of the chromatographic separation and the formation of negative ion (NI) mass spectra are studied by gas chromatography–mass spectrometry (GC–MS) in the resonance electron capture mode, implemented with the minimal technical modification of the domestic serial GC–MS Chromatec-Crystal complex, and a comparison with the basic positive ion (PI) mode upon electron ionization is made. It is found that the chromatographic retention time for isomers increases in direct proportion to the dipole moment of their molecules, illustrating the importance of intermolecular dipole interactions between the polar molecules of the analyte and the stationary phase. It is shown that the chromatograms by the total current of the NI recorded with the fast continuous scanning by the energy of ionizing electrons in the low-energy range 0–10 eV reflect well the component composition of the analyzed sample, and the integral mass spectra of the NI are characteristic of and selective for isomers, and are complementary in information content to the standard PI mass spectra. This is due to the predominance of nitro–nitrite rearrangements and the simple cleavage of the C–NO2 bond during negative ion formation over H-shift reactions, dominating in the formation of PI from TNT isomers.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"80 6","pages":"1089 - 1101"},"PeriodicalIF":1.1,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145162348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Ion-Selective Electrode for the Rapid Determination of Ceftriaxone in Biological Samples 离子选择电极快速测定生物样品中的头孢曲松

IF 1.1 4区化学

Journal of Analytical Chemistry Pub Date : 2025-07-05 DOI: 10.1134/S1061934825700443

S. D. Tatateva, A. Sh. Ramazanov

{"title":"An Ion-Selective Electrode for the Rapid Determination of Ceftriaxone in Biological Samples","authors":"S. D. Tatateva, A. Sh. Ramazanov","doi":"10.1134/S1061934825700443","DOIUrl":"10.1134/S1061934825700443","url":null,"abstract":"An ion-selective electrode is proposed for the rapid determination of ceftriaxone (Ceftr) in biological samples. The ion-pair of octadecylamine (ODA) with ceftriaxone is a ionophore of the ceftriaxone-selective electrode (Ceftr-ISE) membrane. To elucidate the membrane’s operation mechanism, we investigated equilibria in the membrane–solution system as functions of medium acidity and ionophore concentration. At pH values ranging from 6 to 9, the ion pair (ODA)(_{2}^{ + })·Ceftr2– remains stable, and the membrane responds selectively to ceftriaxone. The optimal membrane composition for the Ceftr-ISE was determined as follows (wt %): (ODA)(_{2}^{ + })·Ceftr2– 0.80, polyvinyl chloride 33.06, ODA 1.7 (100 mM), dioctyl sebacate 66.14. The internal electrolyte consisted of Ceftr (0.01 M) and KCl (0.01 M). The electrochemical performance of the Ceftr-ISE membrane was characterized by a linear response range from 1 × 10–5 to 0.1 M, electrode slope of 24.9 mV per decade, and limit of detection of 8.3 × 10–6 M. Potentiometric selectivity coefficients of the Ceftr-ISE were determined using the separate solution method. The electrode enabled the determination of Ceftr in blood and saliva samples from COVID-19 patients. The accuracy of Ceftr quantification was validated using the standard addition method.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"80 6","pages":"1110 - 1116"},"PeriodicalIF":1.1,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145162350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inverted Multivariate Calibrations as an Instrument for the Separate Determination of Similar Analytes from a Mixture Spectrum with Non-Additive Absorbance 反向多元校准作为非加性吸光度混合光谱中相似分析物的分离测定仪器

IF 1.1 4区化学

Journal of Analytical Chemistry Pub Date : 2025-06-17 DOI: 10.1134/S1061934825700248

I. V. Vlasova, A. A. Matusevich, V. I. Vershinin

{"title":"Inverted Multivariate Calibrations as an Instrument for the Separate Determination of Similar Analytes from a Mixture Spectrum with Non-Additive Absorbance","authors":"I. V. Vlasova, A. A. Matusevich, V. I. Vershinin","doi":"10.1134/S1061934825700248","DOIUrl":"10.1134/S1061934825700248","url":null,"abstract":"Multivariate calibrations are used in spectrophotometric analysis to determine multiple analytes in multicomponent solutions. These calibrations relate generalized signals measured at multiple wavelengths with concentrations of the analytes. The aim of this study was to assess the applicability of inverted multivariate calibrations (IMCs) for the separate determination of similar analytes under conditions of nonadditive absorbance. The test samples were model aqueous solutions simultaneously containing Cu(II), Co(II), Ni(II), Zn(II), and Pb(II) along with an excess of the photometric reagent 4-(2-pyridylazo)resorcinol. In these solutions, statistically significant deviations from additive absorbance were observed, likely due to a shift in the complexation equilibrium. The input data for constructing the IMC were the spectra of model mixtures from the training set. The number of analytical wavelengths (m) and the number of mixtures in the training set (n) were varied during the experiment. The metal concentrations in the mixtures of the test set were calculated individually by multiple linear regression, using different spectral regions and different IMCs. The best results were obtained with m = 16 and n = 30. The determination errors for Co, Ni, and Zn in single mixtures did not exceed 25 rel % (in modulo), while the generalized errors (RMSEP) were 10–15 rel %. The determination errors for copper and lead were significantly higher. The experiment demonstrated that IMCs allow to determine the separate components of mixtures with similar but nonadditive spectra. However, the amount of the input data required must be significantly larger than in assessing the total amount of the same analytes, the accuracy of the results will be lower, and the correct determination of all analytes cannot be guaranteed.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"80 5","pages":"856 - 863"},"PeriodicalIF":1.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145143719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of the Phosphomolybdate Blue Colorimetric Method to the Detection of Alkaline Phosphatase Activity 磷酸钼酸盐蓝比色法在碱性磷酸酶活性检测中的应用

IF 1.1 4区化学

Journal of Analytical Chemistry Pub Date : 2025-06-17 DOI: 10.1134/S1061934824605449

Jiajia Xu, Jiamin Lin, Suyan Chen, Zhengzhong Lin

{"title":"Application of the Phosphomolybdate Blue Colorimetric Method to the Detection of Alkaline Phosphatase Activity","authors":"Jiajia Xu, Jiamin Lin, Suyan Chen, Zhengzhong Lin","doi":"10.1134/S1061934824605449","DOIUrl":"10.1134/S1061934824605449","url":null,"abstract":"In this article, a new colorimetric method is proposed to detect the activity of alkaline phosphatase, which is based on the principle that alkaline phosphatase catalyzes the hydrolysis of L-ascorbic acid-2-phosphoric acid trisodium salt, generating ascorbic acid and phosphate. The phosphate then reacts with ammonium molybdate to produce a phosphomolybdenum heteropolyacid, which is further reduced to phosphomolybdic acid blue by SnCl2 with an absorption at 710 nm. Thus, the quantitative detection of alkaline phosphatase (ALP) activity can be achieved by absorbance. The effects of catalytic conditions and test conditions based on the detection results were investigated, and the optimized conditions were determined as Tris-HCl solution at pH 9.5 at room temperature, 150 μmol/L of substrate, 2 mg/L of SnCl2 solution, and 2 mg/L ammonium molybdate-sulfuric acid solution. Under the optimized conditions, the linear range of the method was 2–100 U/L, with a limit of detection of 0.18 U/L. This method was used for the detection of ALP in human serum, with recoveries close to 100%, indicating that this method has potential application prospects. Due to the fast and convenient nature of the test strip sensor technique, the performance of this method on different test strips was studied. It was found that using a polyvinylidene fluoride filter membrane as the test strip enabled rapid and qualitative detection of alkaline phosphatase with high sensitivity.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"80 5","pages":"813 - 821"},"PeriodicalIF":1.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145144040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Analytical Characteristics of Multicapillary Columns with Different Capillary Diameters 不同毛细管直径多毛细管柱的比较分析特性

IF 1.1 4区化学

Journal of Analytical Chemistry Pub Date : 2025-06-17 DOI: 10.1134/S1061934825700273

I. I. Naumenko, A. P. Efimenko, V. K. Soboleva

{"title":"Comparative Analytical Characteristics of Multicapillary Columns with Different Capillary Diameters","authors":"I. I. Naumenko, A. P. Efimenko, V. K. Soboleva","doi":"10.1134/S1061934825700273","DOIUrl":"10.1134/S1061934825700273","url":null,"abstract":"Straight gas-chromatographic multicapillary columns (MCCs) with capillaries of 40 μm diameter (hereinafter 40 μm MCCs) have been known for a long time and are well studied; they are used in portable gas analyzers. Some chromatographic characteristics of the relatively recently developed 25 μm MCCs have also been studied, while commercially available 60 and 80 μm MCCs are poorly studied. In this paper, the main analytical characteristics of 60 and 80 μm MCCs are determined and compared with the characteristics of 25 and 40 μm MCCs. It is shown that the maximum specific efficiency of the columns decreases with increasing column capillary diameter and is approximately 24.8, 18.2, 13.7, and 9.5 thousand theoretical plates (t.p.) per one meter of length for 25, 40, 60, and 80 μm MCCs, respectively. It is found that the height equivalent to a theoretical plate for 60 and 80 μm MCCs does not change much in a wide range of carrier gas (nitrogen and helium) velocities, which allows MCC operation at high carrier gas flow rates without a significant loss of their efficiency. In this case, for all MCCs, the separation rate of peaks with a retention factor of more than 10 exceeds 600 t.p./s, and for peaks with a lower retention factor, it can be several thousand t.p./s, which is significantly higher than for conventional capillary and packed columns. It is found that, for 60 μm MCC and especially 80 μm MCC, very high carrier gas flow rates (up to 1000 cm3/min and more) can be generated at a relatively low pressure drop across the column; therefore they can be used in chromatographic systems requiring high carrier gas flow rates.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"80 5","pages":"912 - 919"},"PeriodicalIF":1.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145144042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Flexible Electrochemical Sensor System for Sweat pH Detection 一种用于汗液pH检测的柔性电化学传感器系统

IF 1.1 4区化学

Journal of Analytical Chemistry Pub Date : 2025-06-17 DOI: 10.1134/S1061934825700315

Mei Wang, Yunqi Liu, Hao Zheng, Liying Jiang

引用次数: 0

A New 2,4-Bis(1H-benzoimidazol-2-yl)-phenol-cupric Complex System for the Detection of Glutathione 一种新的2,4-二（1h -苯并咪唑-2-基）-酚-铜配合物体系检测谷胱甘肽

IF 1.1 4区化学

Journal of Analytical Chemistry Pub Date : 2025-06-17 DOI: 10.1134/S1061934824605607

Yingjie Lei, Xiaofeng Shi, Yanping Shi, Xiangbo Gou

引用次数: 0