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[Association between obesity and the risk of microvascular complications in Yinzhou District, Ningbo adults with type 2 diabetes mellitus]. [宁波市鄞州地区成人2型糖尿病患者肥胖与微血管并发症的关系]。
卫生研究 Pub Date : 2025-07-01 DOI: 10.19813/j.cnki.weishengyanjiu.2025.04.012
Penghao Wang, Zhifeng Xu, Qinkang Lu, Peng Shen, Yuqiong Li, Tao Chen, Wen Ye, Bingqi Li, Lindan Ji
{"title":"[Association between obesity and the risk of microvascular complications in Yinzhou District, Ningbo adults with type 2 diabetes mellitus].","authors":"Penghao Wang, Zhifeng Xu, Qinkang Lu, Peng Shen, Yuqiong Li, Tao Chen, Wen Ye, Bingqi Li, Lindan Ji","doi":"10.19813/j.cnki.weishengyanjiu.2025.04.012","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2025.04.012","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the association between various obesity indices and the risk of developing microvascular complications in adult patients with Type 2 diabetes(T2DM), using cohort data derived from Yinzhou District Health Big Data Platform of China.</p><p><strong>Methods: </strong>This study included adult patients with type 2 diabetes(T2DM) who were enrolled between January 1, 2008, and December 31, 2013, in Yinzhou District, Ningbo, and did not have any microvascular complications at baseline. Data collection encompassed demographic characteristics, lifestyle behaviors, laboratory test result, and physical examination findings, obtained at both baseline and during follow-up periods through structured epidemiological surveys and clinical assessments. Various obesity indices were calculated, including body mass index(BMI), waist-to-height ratio(WHtR), a body shape index(ABSI) and body roundness index(BRI). We also computed the coefficients of variation for these obesity indices during the follow-up period. A Cox proportional hazards regression model was used to analyze the association between obesity indices at baseline and follow-up, and the risk of developing microvascular complications. Additionally, receiver operating characteristic(ROC) curves were used to analyze the predictive efficacy of the coefficients of variation for BMI, WHtR, ABSI and BRI in relation to microvascular complications, and the areas under the curve(AUCs) were calculated.</p><p><strong>Results: </strong>A total of 27 635 patients with type 2 diabetes(T2DM) were included, contributing to 153 717 person-years of follow-up. During this period, 12 969 new cases of microvascular complications were identified, resultsing in an incidence rate of 84.37 cases per 1000 person-years. Patients were categorized into two groups based on the occurrence of complications: those with microvascular complications and those without. There was no significant difference in blood glucose levels between the two groups at baseline. After adjusting for sociodemographic characteristics, laboratory indicators, and potential confounders such as a history of hypertension and hyperlipidemia, it was found that only the WHtR(HR=1.027, 95%CI 1.008-1.046), ABSI(HR=1.035, 95%CI 1.018-1.053) and BRI(HR=1.030, 95%CI 1.011-1.049) were independently associated with the risk of microvascular complications at baseline, while waist circumference(HR=1.010, 95%CI 0.992-1.029) and BMI(HR=0.985, 95%CI 0.967-1.002) were not significantly related(P>0.05). During the follow-up period, the coefficients of variation for all obesity indices were independently associated with an increased risk of microvascular complications. Among them, abdominal obesity indices, such as waist circumference(HR=0.063, 95%CI 1.057-1.069), WHtR(HR=1.060, 95%CI 1.054-1.066), and ABSI(HR=1.062, 95%CI 1.058-1.066), were most strongly linked to the risk of microvascular complications. Further stratified analysis based","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"54 4","pages":"608-620"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Role of SCO1 in regulating microglial mitochondrial copper accumulation in neurological damage of mice exposed to lead and high-glucose diet]. [SCO1在铅和高糖饮食暴露小鼠神经损伤中调节小胶质线粒体铜积累中的作用]。
卫生研究 Pub Date : 2025-07-01 DOI: 10.19813/j.cnki.weishengyanjiu.2025.04.019
Zeming Wang, Xueyan Zhang, Fan Shi, Licheng Yan, Weixuan Wang, Yanshu Zhang
{"title":"[Role of SCO1 in regulating microglial mitochondrial copper accumulation in neurological damage of mice exposed to lead and high-glucose diet].","authors":"Zeming Wang, Xueyan Zhang, Fan Shi, Licheng Yan, Weixuan Wang, Yanshu Zhang","doi":"10.19813/j.cnki.weishengyanjiu.2025.04.019","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2025.04.019","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the mechanism of neurological damage in mice induced by Pb exposure combined with high glucose.</p><p><strong>Methods: </strong>SPF C57 mice were randomly divided into a control group, a Pb group, a high-glucose diet group, and a Pb + high-glucose diet group. Mice in the control group and the Pb group were given basic feed, while those in the high-glucose diet group and the Pb + high-glucose diet group were given a high-glucose diet(50.26% carbohydrates, 21.44% fat, 17.45% protein, 4.21% minerals, and 3.64% fiber). The control group and the high-glucose diet group had free access to pure water, while the Pb group and the Pb + high-glucose diet group were given free access to 250 mg/L Pb acetate water for 12 weeks. The sucrose water preference test and elevated plus maze test were used to assess anxiety and depression-like behaviors in mice. The murine microglial cell line BV-2 was randomly divided into a control group, a Pb group, a high-glucose environment group, and a Pb + high-glucose environment group. The control group received no treatment, the Pb group was given 10 μmol/L Pb acetate, the high-glucose environment group was given 40 mmol/L glucose, and the Pb + high-glucose environment group was given 10 μmol/L Pb acetate and 40 mmol/L glucose for 24 hours. siRNA transfection in BV-2 cells was used to establish a synthesis of cytochrome C oxidase 1(SCO1) knockdown cell model(siSCO1 cells), which were exposed to 10 μmol/L Pb acetate and 40 mmol/L glucose for 24 hours. ICP-MS, immunofluorescence, and kit method were applied to detect copper and Pb content in mice cortex and BV-2 cells. Kits were used to detect superoxide dismutase(SOD) and catalase(CAT) in mice cortex and BV-2 cells. Western blot was used to measure the protein expression of SCO1, ionized calcium binding adaptor molecule 1(Iba-1), interleukin-1β(IL-1β) and interleukin-6(IL-6) in mice cortex and BV-2 cells.</p><p><strong>Results: </strong>The sucrose water preference test result showed that the sucrose water preference rate of mice in the Pb + high-glucose diet group was 31.00%, which was significantly lower than that in the Pb group and the high-glucose diet group(P<0.05). The elevated plus maze result showed that the percentage of entries into the open arms(27.20%) and the percentage of time spent in the open arms(24.20%) of mice in the Pb + high-glucose diet group were significantly lower than those in the Pb group and the high-glucose diet group(P<0.05). The content of SOD in the cerebral cortex of mice in the Pb + high-glucose diet group was 210.96 U/mg prot and the content of CAT was 108.94 U/mg prot, which were significantly lower than those in the Pb group and the high-glucose diet group(P<0.05). The total copper content in the cerebral cortex of mice in the Pb + high-glucose diet group was 4.41 μg/g, which was significantly higher than that in the Pb or high-glucose diet groups alone(P<0.05). Additionally, the e","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"54 4","pages":"663-672"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Association between triglyceride-glucose index and the risk of diabetes among participants with normal fasting serum glucose]. [在空腹血糖正常的受试者中,甘油三酯-葡萄糖指数与糖尿病风险的关系]。
卫生研究 Pub Date : 2025-07-01 DOI: 10.19813/j.cnki.weishengyanjiu.2025.04.005
Yuxiang Yang, Hongtao Yuan, Zengxu Tang, Shuya Cai, Szili-Torok Tamas, Yaqin Yang, Wei Piao, Shuai Zhang, Jing Nan, Fusheng Li, Liyun Zhao, Dongmei Yu
{"title":"[Association between triglyceride-glucose index and the risk of diabetes among participants with normal fasting serum glucose].","authors":"Yuxiang Yang, Hongtao Yuan, Zengxu Tang, Shuya Cai, Szili-Torok Tamas, Yaqin Yang, Wei Piao, Shuai Zhang, Jing Nan, Fusheng Li, Liyun Zhao, Dongmei Yu","doi":"10.19813/j.cnki.weishengyanjiu.2025.04.005","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2025.04.005","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the association between the triglyceride-glucose(TyG) index and the risk of diabetes among Chinese adults with normal fasting serum glucose levels.</p><p><strong>Methods: </strong>A total of 2161 participants were selected from China Nutrition and Health Surveillance(2010-2012) and China Nutrition and Health Follow-up Study(2021), who were not diabetes patients and fasting serum glucose&lt;6.1 mmol/L at baseline. Information on socioeconomic status, lifestyle habits, physical examination, and laboratory examination was collected. TyG index was calculated by fasting serum triglyceride and glucose. Participants were categorized into quartiles based on their baseline TyG index(2010-2012). Multiple adjusted logistic regression analysis was used to explore the association between TyG index and the risk of new-onset type 2 diabetes. Subgroup analysis was conducted among participants stratified by sex, age group, and body mass index(BMI).</p><p><strong>Results: </strong>In 2161 participants, there were significant differences in age, BMI, household income, systolic and diastolic blood pressure, fasting serum total cholesterol, and high-density lipoprotein cholesterol across quartiles of the TyG index. After adjusting for potential confounders such as age, sex, BMI, living area, education level, marital status, household income, current smoking, excessive drinking, leisure physical activity level, family history of diabetes, systolic blood pressure, diastolic blood pressure, fasting serum total cholesterol, and high-density lipoprotein cholesterol, compared with the lowest quartile(Q1), the highest(Q4) showed a 2.82-fold increase in type 2 diabetes risk(95%CI=1.65-4.84, P_(trend)=0.007). Considering TyG index as continuous variable, the risk for diabetes will be 2.22-fold higher with the per unit increase of TyG index(95%CI=1.61-3.06, P&lt;0.001). Subgroup analysis showed that the association remained robust among participants over 45 years old, in males and females alike, and in people with different BMI. And the result showed to be more pronounced among those were over 60 years old, female, and BMI&lt;24. No significant interactions between subgroups and TyG index were observed.</p><p><strong>Conclusion: </strong>Among Chinese adults with normal fasting serum glucose, the TyG index was positively associated with the risk of new onset type 2 diabetes.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"54 4","pages":"557-565"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Distribution of virulence genes of foodborne Bacillus cereus in Beijing from 2021 to 2023]. [2021 - 2023年北京市食源性蜡样芽孢杆菌毒力基因分布]。
卫生研究 Pub Date : 2025-07-01 DOI: 10.19813/j.cnki.weishengyanjiu.2025.04.014
Zheng Lu, Xia Cui, Di Wang, Yi Zhang, Jiali Duan, Rong Zhao
{"title":"[Distribution of virulence genes of foodborne Bacillus cereus in Beijing from 2021 to 2023].","authors":"Zheng Lu, Xia Cui, Di Wang, Yi Zhang, Jiali Duan, Rong Zhao","doi":"10.19813/j.cnki.weishengyanjiu.2025.04.014","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2025.04.014","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the pollution level and the carrying and distribution of virulence genes of foodborne Bacillus cereus in Beijing.</p><p><strong>Methods: </strong>The contamination levels of B. cereus in 805 food items sold in Beijing from 2021 to 2023 was examined and analyzed, and the 10 virulence genes of B. cereus were screened in the isolated stains by PCR. Meanwhile, the distribution of virulence genes related to the production of diarrhea and vomiting toxins was studied.</p><p><strong>Results: </strong>805 pieces of food sold in Beijing have an overall pollution level between 10-5.7×10~4 CFU/g, and no samples with a concentration greater than 10~5 CFU/g have been detected. A total of 37 virulence gene carrige patterns were identified, among which the non-hemolysin gene had the highest carriage rate of 100%(80/80), and the carrier rate of hemolysin BL genes is 65%(52/80). There are 16 strains carrying three non-hemolysin genes and three hemolysin genes simultaneously. The carrying rate of ces gene is 15.0%.</p><p><strong>Conclusion: </strong>The food contamination level of B. cereus in Beijing from 2021 to 2023 is relatively low, but it generally carries virulence genes.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"54 4","pages":"626-630"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Associations between dietary approaches to stop hypertension diet and serum uric acid levels and the risk of hyperuricemia:the mediation role of systematic inflammation]. [停止高血压饮食的饮食方法与血清尿酸水平和高尿酸血症风险之间的关系:系统性炎症的中介作用]。
卫生研究 Pub Date : 2025-07-01 DOI: 10.19813/j.cnki.weishengyanjiu.2025.04.003
Yuxiang Yang, Shuya Cai, Szili-Torok Tamas, Shuai Zhang, Wei Piao, Jing Nan, Fusheng Li, Liyun Zhao, Dongmei Yu
{"title":"[Associations between dietary approaches to stop hypertension diet and serum uric acid levels and the risk of hyperuricemia:the mediation role of systematic inflammation].","authors":"Yuxiang Yang, Shuya Cai, Szili-Torok Tamas, Shuai Zhang, Wei Piao, Jing Nan, Fusheng Li, Liyun Zhao, Dongmei Yu","doi":"10.19813/j.cnki.weishengyanjiu.2025.04.003","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2025.04.003","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the association between adherence to the dietary approaches to stop hypertension(DASH)diet and serum uric acid levels, the risk of hyperuricemia, and the mediation role of systematic inflammation, among Chinese adults from 5 provinces.</p><p><strong>Methods: </strong>China Nutrition and Health Follow-up Study(2021) was conducted based on a part of the participants in China Nutrition and Health Surveillance(2010-2012) and subsequently newly sampled participants. A total of 6963 Chinese adults were selected from and information on socioeconomic status, diet, body measurements, and laboratory examination were investigated. Using the DASH score to evaluate the adherence to the DASH diet, the participants were categorized into quintiles. Using multiple adjustment generalized linear regression and logistic regression analysis the association between DASH diet and serum uric acid level and the risk of hyperuricemia were explored. The mediation role of systematic inflammation on the above associations was evaluated among 2112 participants who were tested for serum high-sensitivity C-reactive protein(hs-CRP).</p><p><strong>Results: </strong>In 6963 participants, the average serum uric acid level was 317.4 μmol/L, and the prevalence of hyperuricemia was 21.18%. The result showed that participants who were 18-44 years, female, overweight or obese, urban residents, higher education level, married, higher household income, non-smokers, higher physical activity level, non-hyperuricemia had higher adherence to the DASH diet(P&lt;0.05). After adjusting for potential confounders, including age, gender, body mass index, living area, education level, marital status, household income, current smoking, excessive drinking, physical activity level, and condition of hypertension, diabetes mellitus, and dyslipidemia, the adherence to DASH diet had a negative association with serum uric acid levels(Q5 vs. Q1, relative concentration =0.93, 95%CI 0.91-0.94, P_(trend)&lt;0.01) and with the risk of hyperuricemia(Q5 vs. Q1, OR =0.59, 95%CI 0.48-0.73, P_(trend)&lt;0.01). Mediation analysis revealed that hs-CRP significantly mediated 17.69%(95%CI 10.22%-25.15%, P_(mediation)&lt;0.01)of the association between DASH diet and serum uric acid level and 26.00%(95%CI 7.50%-44.49%, P_(mediation)&lt;0.01)of the association between DASH score and the risk of hyperuricemia, respectively.</p><p><strong>Conclusion: </strong>Adhering to the DASH diet had negative associations with serum uric acid levels and the risk of hyperuricemia among Chinese adults from 5 provinces. Systematic inflammation may be an important biological mechanism partially mediating the association between the DASH diet on serum uric acid levels and hyperuricemia.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"54 4","pages":"540-548"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Determination of 10 phenolic compounds in vegetables by high performance liquid chromatography]. [高效液相色谱法测定蔬菜中10种酚类化合物]。
卫生研究 Pub Date : 2025-07-01 DOI: 10.19813/j.cnki.weishengyanjiu.2025.04.007
Yanfeng Chen, Huachun Weng, Zengxu Tang, Junjie Lu, Liqiang Wang, Weisheng Xu
{"title":"[Determination of 10 phenolic compounds in vegetables by high performance liquid chromatography].","authors":"Yanfeng Chen, Huachun Weng, Zengxu Tang, Junjie Lu, Liqiang Wang, Weisheng Xu","doi":"10.19813/j.cnki.weishengyanjiu.2025.04.007","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2025.04.007","url":null,"abstract":"<p><strong>Objective: </strong>To establish a high performance liquid chromatography(HPLC) method for determination of flavonoids(epicatechin, L-epicatechin, quercetin, luteolin and kaempferol) and phenolic acids(gallic acid, chlorogenic acid, caffeic acid, p-coumaric acid, and ferulic acid) in vegetables.</p><p><strong>Methods: </strong>Phenolic compounds were isolated by ethanol-water(1∶1, V/V) from homogenized vegetable samples under ultrasonic extraction at 50 ℃ for 10 min. The supernatant after centrifugation was dried and re-dissolved, which was eluted with Symmetry C_(18)(4.6 mm× 250 mm, 5 μm) chromatographic column at 280 nm wavelength, and quantified by external standard method.</p><p><strong>Results: </strong>The 10 phenolic compounds could be separated within 40 min, with linear correlation coefficients greater than 0.999. The detection limit was 0.006-0.034 μg/g, and the limit of quantitation of the method was 0.020-0.100 μg/g. The recoveries of phenolic compounds in the three vegetables were 57.7%-96.8%, and the relative standard deviation of recoveries were less than 11.3%(n=6). The composition and concentration of phenolic compounds in 25 kinds of vegetable samples were different, and the total concentration of phenolic compounds in brassica vegetables were the highest.</p><p><strong>Conclusion: </strong>The method is sensitive, accurate and reproducible, and is suitable for the determination of phenolic compounds in vegetables.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"54 4","pages":"573-581"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Main nutritional components and evaluation of commercially available teas in Guizhou Province]. [贵州省市售茶叶的主要营养成分及评价]。
卫生研究 Pub Date : 2025-07-01 DOI: 10.19813/j.cnki.weishengyanjiu.2025.04.010
Yiyanwen Huang, Yiya Liu, Linjuan He, Shengnan Wu, Hongjiang Long, Wenzheng Liu, Yuehua Pan
{"title":"[Main nutritional components and evaluation of commercially available teas in Guizhou Province].","authors":"Yiyanwen Huang, Yiya Liu, Linjuan He, Shengnan Wu, Hongjiang Long, Wenzheng Liu, Yuehua Pan","doi":"10.19813/j.cnki.weishengyanjiu.2025.04.010","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2025.04.010","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the main nutrient components of commercially available teas in Guizhou Province and to evaluate their nutritional value.</p><p><strong>Methods: </strong>A total of 17 kinds of tea samples(12 kinds of unfermented tea and 5 kinds of fermented tea) with local characteristics were collected in 4 different regions of Guizhou Province, and the samples were divided into 3 batches according to different varieties. According to national standards, direct drying method, Kjeldahl method, Soxhlet extraction method, high performance liquid chromatography, inductively coupled plasma mass spectrometry and other detection method were used for the determination of general nutrients, vitamins, minerals, and ash and other indexes, and the content of the detection indexes was analyzed and made into a comprehensive evaluation of the method of the affiliation function.</p><p><strong>Results: </strong>The differences in general nutrients and ash content among the 17 teas with different tea-making processes were not statistically significant. The differences in carotenoids(9837.52 μgRAE/100 g vs.3042.9 μgRAE/100 g) and vitamin C(206.95 mg/100 g vs.12.42 mg/100 g) between the fermented teas and the unfermented teas were statistically significant(carotenoids Z=-2.85, vitamin C Z=-2.21, P&lt;0.05). The difference between sodium content in fermented and unfermented tea(42.65 mg/100 g vs.32.87 mg/100 g) was statistically significant(Z=-2.11, P&lt;0.05) and there were synergistic and antagonistic effects between the elements, sodium and phosphorus(r=0.592, P&lt;0.05), manganese and iron(r= 0.673, P&lt;0.01) showed significant positive correlation. According to the comprehensive evaluation by membership function method, the highest nutritional quality varieties were Kaiyang selenium rich tea(X_μ= 0.5944), Zunyi Maofeng(X_μ=0.5872), Meitan Cuiya(X_μ= 0.5844) and Fanjingshan Cuifeng(X_μ= 0.5506).</p><p><strong>Conclusion: </strong>Most of the nutritional values of unfermented tea in commercially available tea in Guizhou were higher than those of fermented tea, and from the nutritional point of view, green tea retained more natural components.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"54 4","pages":"593-598"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sleep quality and mental health after bloodborne occupational exposure among medical staff in a new crown square cabin: chain mediation of social support and psychological resilience]. 新冠方舱医务人员血源性职业暴露后睡眠质量与心理健康:社会支持与心理弹性的连锁中介作用
卫生研究 Pub Date : 2025-07-01 DOI: 10.19813/j.cnki.weishengyanjiu.2025.04.015
Guoai Yao, Beina Mu, Zhigang Huang, Yali Feng, Sheng Li, Jinyu Wang
{"title":"[Sleep quality and mental health after bloodborne occupational exposure among medical staff in a new crown square cabin: chain mediation of social support and psychological resilience].","authors":"Guoai Yao, Beina Mu, Zhigang Huang, Yali Feng, Sheng Li, Jinyu Wang","doi":"10.19813/j.cnki.weishengyanjiu.2025.04.015","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2025.04.015","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the relationship between sleep quality, social support, psychological resilience and mental health status of medical staff following bloodborne occupational exposure in a square pod hospital, and the mediating role of social support and psychological resilience.</p><p><strong>Methods: </strong>A whole group sample of medical staff who had blood-borne occupational exposure in Lanzhou City Square Cabin Hospital from November to December 2022 were surveyed using self-administered general information questionnaire, Pittsburgh Sleep Quality Index(PSQI), self-reporting inventory(SCL-90) scale, social support rating scale(SSRS) and psychological resilience scale(CD-RISC), and SPSS 27.0 software and Process V 4.1 plug-in were used to analyze the quality of medical staff&apos;s sleep, psychological well-being, relationships between social support and psychological resilience were analyzed.</p><p><strong>Results: </strong>(1) A total of 332 medical personnel who had experienced blood-borne occupational exposure were investigated in this study. Most of them were male(n=254, 76.51%), mostly aged 26-45 years(n=262, 78.92%), and the majority of them were aged 11-19 years(n=138, 41.57%). The detection rate of needle stab injury was 73.49%(n=244), and the detection rate of sharp instrument injury was 82.53%(n=274). The detection rate of sleep disorder was 60.84%(n=202) and the positive rate of SCL-90 was 50.30%(n=167). (2) The total score of sleep quality was negatively correlated with the total score of social support(r=-0.257, P&lt;0.01), the total score of mental resilience was negatively correlated with r=-0.276, P&lt;0.01, and the total score of symptom checklist was positively correlated with r=0.580, P&lt;0.01. The total score of SSCS was negatively correlated with the total score of social support(r=-0.286, P&lt;0.01) and the total score of mental resilience(r=-0.403, P&lt;0.01). The total score of social support was positively correlated with the total score of mental resilience(r=0.406, P&lt;0.01). (3) Sleep quality had a direct negative effect on mental health, with an effect value of 11.83%(95%CI 0.462-1.386). Psychological resilience mediated the relationship between sleep quality and mental health, with an effect value of 5.43%(95%CI 0.093-0.837). Social support and psychological resilience mediated the relationship between sleep quality and mental health. mediating role, with an effect value of 2.66%(95%CI 0.080-0.353).</p><p><strong>Conclusion: </strong>Overall poor sleep quality and mental health among medical staff following bloodborne occupational exposure in square pod hospitals, in which social support and psychological resilience play chain-mediated roles.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"54 4","pages":"631-637"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Associations between parental control and prosocial behavior among middle school students in Xuancheng and Suzhou in 2022: Mediating role of peer relationships]. [2022年宣城、苏州地区中学生父母控制与亲社会行为的关系:同伴关系的中介作用]。
卫生研究 Pub Date : 2025-07-01 DOI: 10.19813/j.cnki.weishengyanjiu.2025.04.017
Zhenghao Qi, Zhiyuan Qi, Wengeng Han, Hui Han
{"title":"[Associations between parental control and prosocial behavior among middle school students in Xuancheng and Suzhou in 2022: Mediating role of peer relationships].","authors":"Zhenghao Qi, Zhiyuan Qi, Wengeng Han, Hui Han","doi":"10.19813/j.cnki.weishengyanjiu.2025.04.017","DOIUrl":"10.19813/j.cnki.weishengyanjiu.2025.04.017","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To explore the relationship between the level of parental control and peer relationships and prosocial behavior of junior high school students.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;In June-July 2022, a total of 2564 junior high school students were selected from one junior high school in each of the urban, rural and combined urban and rural areas of Xuancheng City and Suzhou City, Anhui Province, using random whole cluster sampling to collect data using the Level of Parental Control Scale, the Tendency to Prosocial Behavior Scale for Junior High School Students, and the Children&apos;s Junior High School Student Peer Relationships Scale, and the SPSS 25.0 software was used to data were analyzed, descriptive analysis, t-test, ANOVA and correlation analysis were performed on the data, and the mediating effects of parental control and prosocial behavior were verified using the bias-corrected nonparametric percentile Bootstrap method.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The study population consisted of 1281 boys and 1283 girls, aged between 11 and 17 years with a mean age of(13.39±0.80) years. Male students had higher parental control score than female students(185.31±27.49 vs 178.21±25.13, P&lt;0.01) and male students had lower peer relationship score than female students(47.13±10.84 vs 48.41±11.26, P&lt;0.01). Rural students had lower parental control scores than urban and urban-rural students(172.47±25.40 vs 183.03±24.63 vs 190.37±26.61, P&lt;0.01). Rural students had higher peer relationship scores than urban and urban-rural students(49.57±10.57 vs 48.33±10.84 vs 45.25±11.39, P&lt;0.01). Rural students had lower pro-social behavior scores than urban and combined urban and rural students(86.27±16.98 vs 91.64±17.26 vs 95.14±19.27, P&lt;0.01). The differences in parental control and peer relationship scores among middle school students of different genders were statistically significant(P&lt;0.01). The differences in parental control, pro-social behavior and peer relationship scores among students from different cities, urban-rural areas and rural areas were statistically significant(P&lt;0.01). Parental control was positively correlated with both pro-social behavior scores of junior high school students(r=0.315). Peer relationship played a masking effect between parental control and junior high school students&apos; pro-social behavior(a×b and c' heteroscedastic, |a×b|/c'=8.50%). Among students in rural and urban-rural combined areas, peer relationship played a masking effect between parental control and junior high school students&apos; prosocial behavior(a×b and c' heteroscedastic, |a×b|/c'=17.81%), and the mediating effect of peer relationships was not statistically significant among students in urban areas(Bootstrap 95% CI-0.0157-0.004).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Parental control positively affects peer relationships and prosocial behavior among junior high school students, and good peer relationships significant","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"54 4","pages":"646-653"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Relationship between nurses' sleep quality and quality of life in class Ⅲ grade a hospitals in Lanzhou in 2023: the chain mediating role of social support and psychological resilience]. [2023年兰州市Ⅲ三级甲等医院护士睡眠质量与生活质量的关系:社会支持和心理弹性的连锁中介作用]。
卫生研究 Pub Date : 2025-07-01 DOI: 10.19813/j.cnki.weishengyanjiu.2025.04.016
Yanni Zheng, Qing Guo, Yan Wang, Lian Li, Rong Zhao
{"title":"[Relationship between nurses' sleep quality and quality of life in class Ⅲ grade a hospitals in Lanzhou in 2023: the chain mediating role of social support and psychological resilience].","authors":"Yanni Zheng, Qing Guo, Yan Wang, Lian Li, Rong Zhao","doi":"10.19813/j.cnki.weishengyanjiu.2025.04.016","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2025.04.016","url":null,"abstract":"<p><strong>Objective: </strong>To explore the relationship between sleep quality and quality of life of nurses in tertiary hospitals, and to verify the chain-mediated role of social support and psychological resilience.</p><p><strong>Methods: </strong>A questionnaire survey was conducted from November to December 2023 on 732 nurses from three tertiary hospitals in Lanzhou City, China, using cross-sectional whole cluster sampling. The Quality of Life Scale(SF-36), the Psychological Resilience Scale(CD-RISC), the Pittsburgh Sleep Quality Index(PSQI), and the Social Support Rating Scale(SSRS) were applied to measure their quality of life, psychological resilience, quality of sleep, and social support levels. A partial correlation was used to determine the relationship between the factors.</p><p><strong>Results: </strong>(1) The demographic characteristics were dominated by females(95.5%), Han Chinese(98.2%), and bachelor&apos;s degree(83.6%); the occupation-related characteristics were dominated by the length of service of 6-10 years(39.9%) and 11-19 years(38.5%), and the job title was dominated by nurse practitioner(52.9%). (2) Nurses&apos; sleep quality was negatively correlated with the level of social support(r=-0.226, P&lt;0.01), negatively correlated with the level of psychological resilience(r=-0.118, P&lt;0.01), and negatively correlated with the level of quality of life(r=-0.502, P&lt;0.01). The level of social support and the level of psychological resilience were positively correlated(r=-0.311, P&lt;0.01). and positively correlated with the level of quality of life(r=0.347, P&lt;0.01). The level of psychological resilience was positively correlated with the level of quality of life(r=0.382, P&lt;0.01). (3) The sleep status of nurses had a direct impact on the quality of life, that is, the direct effect was significant(Direct effect accounted for 84.3%, 95%CI-18.951-13.099). The degree of social support has a significant partial mediating effect between sleep quality and quality of life, that is, indirect effect 1(Indirect effect 1 accounted for 9.84%, 95%CI-4.261--1.179). The degree of social support and the level of mental resilience have significant chain mediating effect between sleep quality and quality of life, that is, indirect effect 2 is significant(Indirect effect 2 accounted for 5.33%, 95%CI-1.710--0.682).</p><p><strong>Conclusion: </strong>Level of social support and level of psychological resilience chain-mediated the relationship between sleep status and quality of life among nurses.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"54 4","pages":"638-645"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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