卫生研究最新文献

{"title":"[Survey on chloropropanol esters content and characteristics in commercially available vegetable oils and exposure assessment].","authors":"Luyue Wang, Feng Pan, Pei Cao, Lei Zhang, Jianwen Li, Pingping Zhou, Dajin Yang","doi":"10.19813/j.cnki.weishengyanjiu.2026.02.021","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2026.02.021","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the levels of chloropropanol esters(MCPDE) in commercially available vegetable oils in 2022 and their potential dietary health risks.</p><p><strong>Methods: </strong>Dietary exposure assessment was conducted using the simple distribution approach, based on 2022 national food safety risk monitoring data and 2018-2020 national food consumption data.</p><p><strong>Results: </strong>The average detection rates of 3-monochloro-1, 2-propanediol(3-MCPDE) and 2-monochloro-1, 3-propanediol(2-MCPDE) in vegetable oils were 67.07% and 58.84%, respectively, with average concentrations of 0.86 and 0.47 mg/kg. The average exposure levels of 3-MCPDE and 2-MCPDE from vegetable oil intake in the general population were 0.374 and 0.204 μg/(kg·BW·d), respectively; for high-consumption individuals(P95), the exposure levels were 1.062 and 0.580 μg/(kg·BW·d). The average exposure levels across age groups ranged from 0.298 to 0.737 and 0.163 to 0.403 μg/(kg·BW·d), respectively; while P95 exposures ranged from 0.834 to 2.011 and 0.456 to 1.099 μg/(kg·BW·d), respectively. For the general population and the P95 group in China, the 3-MCPDE exposure from vegetable oil intake accounted for 9.4% and 26.6% of their provisional maximum tolerable daily intake(PMTDI), respectively. while the average and P95 exposure levels across all age groups accounted for 7.5%-18.4% and 20.9%-50.3% of their respective PMTDI.</p><p><strong>Conclusion: </strong>3-MCPDE and 2-MCPDE were detected in some commercially available vegetable oils in China, with 3-MCPDE levels higher than 2-MCPDE. Dietary exposure assessments indicate that the current health risk from 3-MCPDE in vegetable oils is low.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"55 2","pages":"319-325"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association between energy-adjusted dietary inflammatory index and cognitive function in individuals aged 55 and over across four Chinese provinces from 2018 to 2019].","authors":"Zhongting Lu, Zhiru Wang, Liusen Wang, Hongru Jiang, Jiguo Zhang, Zhihong Wang","doi":"10.19813/j.cnki.weishengyanjiu.2026.02.010","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2026.02.010","url":null,"abstract":"<p><strong>Objective: </strong>To examine the association between the energy-adjusted dietary inflammatory index(E-DII) and multiple cognitive domains, and to assess potential interactions across population subgroups.</p><p><strong>Methods: </strong>Baseline data(2018-2019) from the Community Cohort Study of Neurological Diseases(CCSNSD) were analyzed. Cognitive function was assessed using the Montreal cognitive assessment(MoCA), covering six domains in the following order: memory(memory index score, MIS), executive function(executive index score, EIS), visuospatial ability(visuospatial index score, VIS), language(language index score, LIS), attention(attention index score, AIS), and orientation(orientation index score, OIS). Generalized linear models evaluated associations between E-DII and domain-specific scores, with stratified analyses by age, gender, education(level), and income(level). Restricted cubic spline models were used to assess dose-response relationships.</p><p><strong>Results: </strong>Each one-unit increase in E-DII was significantly associated with lower scores in AIS, EIS, LIS, MIS, and OIS(all β&lt;0, P&lt;0.05), with the strongest inverse association observed for attention(AIS; β=-1.243, P&lt;0.001). VIS scores were significantly lower in the higher E-DII quartiles(Q3 and Q4; P&lt;0.05). Restricted cubic spline analyses showed a progressive decline in cognitive domain scores with increasing E-DII, with steeper decreases at higher E-DII levels. These associations were most evident among individuals aged 65-74 years, women, and those with lower education or income level.</p><p><strong>Conclusion: </strong>A higher dietary inflammatory potential was linked to poorer cognitive performance. This associationwas particularly pronounced among women, individuals with lower education levels, and those with lower income.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"55 2","pages":"230-237"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Bibliometric mapping of the application of artificial intelligence in nutrition: a visualization analysis].","authors":"Yunshang Cui, Zengxu Tang, Hongtao Yuan, Yuanyuan Xu","doi":"10.19813/j.cnki.weishengyanjiu.2026.02.020","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2026.02.020","url":null,"abstract":"<p><strong>Objective: </strong>To reveal the knowledge structure, research hotspots, and development trends in the field of nutrition through visual analysis of core literature on the application of artificial intelligence(AI), providing a reference for nutritional research.</p><p><strong>Methods: </strong>Using bibliometric method, we retrieved relevant literature from the Web of Science database between 2016 and 2024, limiting the literature types to original articles or reviews. CiteSpace 6.4. R1 software was used for visual analysis, including keyword co-occurrence, clustering, timeline, and emergence analysis, to construct a knowledge graph and analyze author, institutional collaboration networks, and research themes.</p><p><strong>Results: </strong>A total of 1896 core papers were included, showing an accelerating growth trend in publication volume, entering a rapid growth phase after 2021, with a total growth rate of 485.7% and an average annual growth rate of 19.8%. Core authors included 78 individuals, accounting for 25.74% of all researchers, publishing 433 papers, which accounted for 22.84% of the total literature. Research institutions were mainly concentrated in China and the United States, with the University of California and Harvard University in the U. S. , and the Chinese Academy of Sciences and the Chinese Academy of Medical Sciences/Union Medical College in China, occupying core positions in the collaboration network. Keyword analysis revealed that keywords such as \"machine learning\"\"metabolic syndrome\"\"gut microbiota\" were high-frequency terms, accounting for 45.31% of the total word frequency. Keyword clustering analysis formed 11 thematic clusters, covering key application scenarios such as chronic disease risk assessment and personalized dietary interventions. The keyword burst analysis reveals evolving research priorities, shifting from disease-diet association studies to nutrition interventions, mental health, and technical standardization.</p><p><strong>Conclusion: </strong>The findings indicate that AI applications in nutrition are advancing toward diversified and refined development. Future efforts should emphasize interdisciplinary collaboration to promote standardized and policy-driven implementation of these technologies.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"55 2","pages":"311-318"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Diabetes and dyslipidemia status among adult residents in Xinjiang Uygur Autonomous Region in 2015].","authors":"Xiaoli Xu, Shujuan Li, Qiya Guo, Xue Cheng, Hongyun Fang, Lahong Ju, Weiyi Gong, Xiaoqi Wei, Wenwen Du, Jiguo Zhang, Huijun Wang","doi":"10.19813/j.cnki.weishengyanjiu.2026.02.003","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2026.02.003","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the prevalence, awareness, and control rates of diabetes and dyslipidemia among adult residents in Xinjiang Uygur Autonomous Region in 2015.</p><p><strong>Methods: </strong>Based on data from the 2015 China Chronic Disease and Nutrition Surveillance, adults aged 18 years and older in Xinjiang with complete demographic information and data related to diabetes and blood lipids were selected as 4666 study subjects.</p><p><strong>Results: </strong>In 2015, the prevalence of diabetes among adults aged ≥18 years in Xinjiang Uygur Autonomous Region was 7.1%. The prevalence was significantly higher in men(8.0%) than in women(6.2%), and higher in urban(9.0%) than in rural(5.3%) areas. By age group, the prevalence was highest in adults aged ≥60 years(13.7%), followed by those aged 45-59 years(8.9%) and 18-44 years(2.4%)(all P&lt;0.05). The prevalence of dyslipidemia was 46.6%, with low high-density lipoprotein cholesterol(HDL-C) being the most prevalent subtype(34.0%). The prevalence rates of dyslipidemia, hypertriglyceridemia, and low HDL-C were significantly higher in males than in females(P&lt;0.05). The prevalence of hypertriglyceridemia was higher in urban(17.0%) than in rural areas(12.4%), while the prevalence of low HDL-C was higher in rural(35.7%) than in urban areas(31.9%)(P&lt;0.05). The prevalence of hypercholesterolemia and high LDL-C was higher in older adults, whereas that of low HDL-C was higher in younger adults(P&lt;0.05). In this study, the awareness rates for diabetes and dyslipidemia were 52.9% and 18.1%, respectively. The treatment rates among patients with diabetes and dyslipidemia were 46.2% and 11.0%, respectively. Awareness and treatment rates for dyslipidemia were higher in adult females than in males(P&lt;0.05). Urban residents had higher awareness rates for dyslipidemia and higher treatment rates for both diabetes and dyslipidemia than rural residents(P&lt;0.05). Awareness and treatment rates for both diabetes and dyslipidemia showed increasing trends with age(P&lt;0.05).</p><p><strong>Conclusion: </strong>The prevalence of diabetes in Xinjiang is slightly lower than the national average, but dyslipidemia is prominent, particularly low HDL-C, with a noticeable trend of younger onset.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"55 2","pages":"188-194"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Effects of high-fat diet on gut microbiota in rats transplanted with gut microbiota from normal/high triglyceridemic individuals].","authors":"Di Chen, Bing Zhang, Ou Wang, Xiyue Zhang, Jian Huang","doi":"10.19813/j.cnki.weishengyanjiu.2026.02.014","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2026.02.014","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;Using sterile SD rats as a model, the fat accumulation and changes in the intestinal flora of rats transplanted with normal/high triglyceride(TG) population under high-fat diet were studied.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;10-week-old male sterile rats were randomly divided into 3 groups according to body weight, with 6 rats in each group. The non-colonizing group was gavaged with normal saline, the normal lipid group was gavaged with normal TG(&lt;1.7 mmol/L) human intestinal flora, and the high TG group was gavaged with high TG(≥1.7 mmol/L) human intestinal flora. Rats were given fecal bacterial solution by gavage at a dose of 1 mL per 100 g of body weight, every other day, for a total of 3 times, followed by 2 weeks of adaptive growth of the microbiota. After the transplanting was completed, a 9-week feeding experiment with high-fat diet(fat energy supply ratio 40.5%) was conducted. The body weight of the rats was measured weekly, and feces were collected every three weeks. After the experiment, liver, perirenal, subcutaneous and brown fat were weighed. The fat weight was used to represent the fat accumulation of the rats, and lipid indicators were determined. Liver HE staining was used to observe steatosis, and high-throughput sequencing was used to analyze the intestinal flora of the rats.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;After the experiment, compared with the colonized normal TG population microbiota group, there were no significant differences in body weight, perirenal, subcutaneous and brown fat mass, and blood lipid levels in the colonized high TG microbiota group. Liver HE staining sections showed that both the colonized high TG and non-colonized dyslipidemia microbiota groups could observe more severe steatosis and obvious fat vacuums. The intestinal microbiota profiles of the two groups of rats colonized with different population microbiota showed different variation patterns at the phylum and genus levels. At 0 weeks of high-fat diet, the F/B ratios of the microbiota phylum in rats colonized with the feces of the high-TG population and those colonized with the feces of the normal TG population were 1.24 and 0.48, respectively. After 9 weeks of high-fat diet, The F/B ratios of the Firmicutes and Bacteroidetes phyla of the bacteria phyla in rats colonized with the feces of the high TG population and those colonized with the feces of the normal TG population were 3.37 and 0.81, respectively. In the fecal colonization group of rats in the high TG population under a high-fat diet, more obvious intestinal flora disorders occurred, the relative abundance of beneficial bacteria was inhibited, and the relative abundance of pathogenic bacteria increased.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Under high-fat diet, the colonization of intestinal flora in volunteers with different blood lipid levels has a certain relationship with the weight changes and fat accumulation of rats. The species composition and abundance of ","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"55 2","pages":"261-268"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association between 24 h activity behaviors and body fat percentage among children with intellectual disabilities: based on compositional data analyses].","authors":"Yaqing Yuan, Yang Liu, Jingmin Liu","doi":"10.19813/j.cnki.weishengyanjiu.2026.02.012","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2026.02.012","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the correlation between 24 h activity behaviors and body fat percentages in children with intellectual disabilities(ID), and the changes in body fat percentage of children with ID after isochronous substitution between behaviors in 24 h activity behaviors.</p><p><strong>Methods: </strong>From February to May 2024, the stratified random sampling strategy to recruit 207 children with ID aged 6-12 years old from six special education schools in Jinan City. The 24 h activity behaviors were assessed using triaxial accelerometers, and body fat percentages(BF%) were measured with a multi-frequency bioelectrical impedance analyzer. Compositional data were analyzed in R. Multiple linear regression examined associations between 24 h activity behaviors and BF%. Using 5-min increments, the isotemporal substitution was applied to explore dose-response effects of reallocating time between behaviors.</p><p><strong>Results: </strong>The time in moderate-to-vigorous physical activity(MVPA) was negatively correlated with BF%(β=-3.68, P&lt;0.01), and the time of SB was positively correlated with body fat percentage(β=3.78, P&lt;0.01); reallocating time to MVPA significantly reduced BF% when replacing sleep(SLP), SB, and light-intensity physical activity(LPA) by 1.39%, 1.99%, and 1.51%, respectively. The substitution effects between MVPA and SLP/SB/LPA were asymmetric. Replacing SB with LPA reduced BF% by 0.47%, and replacing SB with sleep reduced BF% by 0.59%; substitution effects among LPA, SLP, and SB were approximately symmetric.</p><p><strong>Conclusion: </strong>Among children with ID, 24 h activity behaviors are associated with BF%. Of all substitutions analyzed, replacing SB with MVPA produced the greatest reduction in BF%.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"55 2","pages":"247-252"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Physical activity and leisure sedentary behavior among adult residents in Xinjiang Uygur Autonomous Region in 2015].","authors":"Yongqi Ding, Hongyun Fang, Xiaoli Xu, Rong Zhang, Shujuan Li, Lahong Ju, Osmanjan Xayida, Xue Cheng, Xiaoqi Wei, Weiyi Gong, Wenwen Du, Jiguo Zhang, Huijun Wang, Qiya Guo","doi":"10.19813/j.cnki.weishengyanjiu.2026.02.007","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2026.02.007","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the physical activity and leisure-time sedentary behavior patterns among adults aged 18 years and older in Xinjiang Uyghur Autonomous Region in 2015.</p><p><strong>Methods: </strong>Using physical activity data from the 2015 China Adult Chronic Disease and Nutrition Surveilance, this study analyzed the physical activity levels, exercise habits, and leisure-time sedentary behavior duration among adults in Xinjiang across different demographic subgroups. Multivariate logistic regression analysis was used to examine the effects of different demographic factors on exercise-related behaviors and physical inactivity rates. Non-parametric tests were employed to assess differences in the distribution of daily leisure-time sedentary behavior duration.</p><p><strong>Results: </strong>In 2015, the physical inactivity rate among adult residents in Xinjiang was 23.3%, with 9.4% engaging in regular exercise and 86.3% never exercising. There were statistically significant differences in the rates of regular exercise and physical inactivity among different age groups, educational levels, and occupations(P&lt;0.05). The median and mean±standard deviation of leisure-time sedentary behavior time among Xinjiang residents were 170(120, 240) min/d and 189.8±130.9 min/d, respectively. Men had higher values than women(P&lt;0.0001), and higher in urban areas than in rural areas(P&lt;0.0001). Leisure-time sedentary behavior time decreased with increasing age(P&lt;0.0001) and increased with higher educational attainment(P&lt;0.0001). The primary leisure-time sedentary behavior was watching television, with a median and mean of 120(60, 180) min/d and 120.4±79.4 min/d, respectively; followed by using mobile phone, with a median and mean of 10(0, 40) min/d and 34.6±61.8 min/d, respectively. Statistically significant differences in leisure-time sedentary behavior duration were observed across different occupations and marital statuses(P&lt;0.0001).</p><p><strong>Conclusion: </strong>In 2015, insufficient physical activity was prevalent among adult residents in Xinjiang, characterised by low exercise rates and prolonged leisure-time sedentary behaviour predominantly involving electronic screen use. Particular attention should be directed towards the physical activity levels and sedentary habits of males, young adults, rural residents, and professionals.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"55 2","pages":"210-218"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Differences in DNA methylation alterations in blood samples from patients with silicosis and coal workers' pneumoconiosis].","authors":"Zitong Chen, Xue Li, Rangrang Su, Yiwen Dong, Lin Zhang, Xin Wang, Ning Kang, Hongying Bian, Ying Xia, Meng Ye","doi":"10.19813/j.cnki.weishengyanjiu.2026.02.019","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2026.02.019","url":null,"abstract":"<p><strong>Objective: </strong>To explore the biological processes and regulatory mechanisms of methylation alterations in genes involved in silicosis and coal workers&apos; pneumoconiosis(CWP).</p><p><strong>Methods: </strong>Differentially methylated genes(DMGs) volcano map, pheatmap package was used to construct heatmap; using sesame(SEnsible Step-wise Analysis of DNA MEthylation BeadChips) software mixed linear model for each two groups of samples were analyzed to obtain the detected differentially methylated CpG(DMC) sites, then FDR corrected to obtain the corrected P value, and screened using P&lt;0.05 and Δβ absolute value &gt;0.05. Gene ontology(GO) enrichment was performed on the differentially methylated gene analysis to find the biological processes in which they are mainly involved, kyoto encyclopedia of genes and genomes(KEGG) pathway analysis was used to find relevant cellular pathways that may be involved, and potential biomarkers were further identified based on the overlap of Venn diagrams and the result of unique DMGs.</p><p><strong>Results: </strong>The group of silicosis patients consisted of 4 males and 1 female, with an average age of(54.60±2.70) years old and an average duration of occupational hazard exposure of(12.80±8.01) years. Coal workers&apos; pneumoconiosis patient group had 15 males and 1 female, with an average age of(74.80±8.14) years old and an average duration of occupational hazard exposure of(31.38±10.11) years. The control group consisted of 49 males and 7 females with a mean age of(64.91±12.29) years old. The differences in age(F=7.78, P&lt;0.01), length of service(t=4.67, P&lt;0.01), and smoking(χ~2=16.41, P&lt;0.01) were statistically significant between the groups, and the differences in gender(χ~2=0.88, P&gt;0.05) were not statistically significant between the groups. The result of gene sequencing showed that there were 1128 significantly different DMGs(including 720 up-regulated and 408 down-regulated DMGs) in the group of silicosis patients compared to the control group. A total of 423 significantly different DMGs were found in the group of CWP patients(including 139 up-regulated and 284 down-regulated DMGs). Compared to CWP, a total of 711 significantly different DMGs were found in the group of silicosis patients(including 440 up-regulated and 271 down-regulated DMGs). GO enrichment analysis showed that the differential genes between silicosis and CWP were associated with 276 biological processes, 45 cellular components, and 64 molecular functions. KEGG analysis revealed that the differential genes were significantly enriched in 30 signaling pathways.</p><p><strong>Conclusion: </strong>There are differences in the distribution of DMGs in blood samples from patients with silicosis and CWP, as well as in the involved biological processes and regulatory mechanisms.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"55 2","pages":"297-310"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Energy and nutrients intakes among adult residents in Xinjiang Uygur Autonomous Region from 1982 to 2015].","authors":"Xiaoqi Wei, Huijun Wang, Jiguo Zhang, Hongyun Fang, Lahong Ju, Wenwen Du, Weiyi Gong, Qiya Guo, Shujuan Li, Xiaoli Xu, Xue Cheng, Aidong Liu","doi":"10.19813/j.cnki.weishengyanjiu.2026.02.001","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2026.02.001","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To analyze changes in dietary structure and energy and nutrient intakes among adult residents aged 18-64 years in the Xinjiang Uygur Autonomous Region from 1982 to 2015.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Study participants were drawn from five national nutrition surveys and surveillance programs(1982, 1992, 2002, 2010-2012, and 2015). Adult residents aged 18-64 years in the Xinjiang Uygur Autonomous Region with complete data were included; pregnant women, lactating women, and individuals with abnormal energy intake(&lt;500 kcal/d or &gt;5000 kcal/d) were excluded. The numbers of participants included for each year were 2660, 1672, 789, 391, and 1384, respectively. Dietary assessment method included the weighed food record method, household food inventory method, 3-day 24-hour dietary recall method, and condiment weighing method(with slight method ological differences across years). Food consumption data were converted into energy and nutrient intakes per day using food composition tables. The adequacy of macronutrient intake was evaluated according to the acceptable macronutrient distribution ranges(AMDRs: protein 10%-15%, fat 20%-30%, carbohydrate 50%-65%) specified in the Chinese Dietary Reference Intakes(2023 edition). Statistical analyses were conducted using SAS software. Categorical variables were described as frequencies(percentages), and energy and nutrient intakes were described as mean±standard deviation. Differences in population characteristics across years were assessed using the chi-square test. Trend analyses of macronutrient intakes relative to DRIs in 2015 were performed using the nonparametric Jonckheere-Terpstra test. Temporal trends in energy and nutrient intakes were analyzed using linear regression. An α value of 0.05 was considered statistically significant.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;This study showed that from 1982 to 2015, the dietary structure of adult residents in the Xinjiang Uygur Autonomous Region underwent a transition from a high-carbohydrate, low-fat pattern to a high-fat, moderate-protein pattern. Energy intake exhibited a trend of initial increase followed by decrease. Overall, the proportion of the population with protein energy contribution within the AMDR increased, rising from 38.6% in 1982 to 66.2% in 2015, while the proportion with protein energy contribution exceeding 15% increased year by year, indicating improvement in protein nutritional status. The proportion of individuals with fat energy contribution exceeding 30% increased from 26.3% to 43.9%, and the proportion with carbohydrate energy contribution below 50% rose to 22.5%. Significant differences in energy and nutrient intakes were observed between urban and rural residents and between sexes. Urban residents experienced a greater decline in energy intake(from 2561.6 kcal/d to 2067.2 kcal/d), and women showed a larger reduction in mean daily energy intake(from 2405.3 kcal/d to 2059.8 kcal/d). Among rural residents","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"55 2","pages":"173-179"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Obesity and related health status among children and adolescents aged 7-17 years in Xinjiang Uygur Autonomous Region from 2016 to 2017].","authors":"Youxia Ren, Huijun Wang, Hongyun Fang, Muyiduli Xiamusiye, Jiguo Zhang, Lahong Ju, Jun Zhang, Weiyi Gong, Xiaoqi Wei, Qiya Guo, Shujuan Li, Xiaoli Xu, Xue Cheng, Wenwen Du","doi":"10.19813/j.cnki.weishengyanjiu.2026.02.008","DOIUrl":"https://doi.org/10.19813/j.cnki.weishengyanjiu.2026.02.008","url":null,"abstract":"<p><strong>Objective: </strong>To assess the prevalence of obesity and related health conditions among children and adolescents aged 7-17 in the Xinjiang Uygur Autonomous Region from 2016 to 2017.</p><p><strong>Methods: </strong>The data were sourced from the 2016-2017 China Children and Lactating Mothers Nutrition and Health Surveillance Program. A total of 1112 individuals were surveyed in this study, with 754 from urban schools and 358 from rural schools. Among them, boys accounted for 49.01% and girls for 50.99%; students aged 7-11 years comprised 49.01%, and those aged 12-17 years comprised 50.99%. Obesity, central obesity, hypertension, diabetes, and dyslipidemia were defined according to the following criteria: \"Screening for Overweight and Obesity Among School-Age Children and Adolescents(WS/T 586-2018)\", \"Threshold for High Waist Circumference Screening in Children and Adolescents Aged 7-18 Years(WS/T 611-2018)\", \"Blood Pressure Reference for Hypertension Screening in Chinese Children and Adolescents Aged 7-18 Years\", \"Guidelines for the Diagnosis and Treatment of Type 2 Diabetes in Children(2025)\", and \"Chinese Guidelines for Lipid Management(2023)\". Referring to the clinical obesity definition and diagnostic criteria framework proposed by the Lancet Diabetes &amp; Endocrinology Commission, and considering the availability of indicators in this study, criteria for defining subclinical obesity and clinical obesity in children and adolescents were established.</p><p><strong>Results: </strong>The general obesity rate was 3.96%, and the central obesity rate was 9.44%. According to the clinical obesity criteria, the subclinical obesity rate was 2.34%, and the clinical obesity rate was 0.45%. The general obesity rate, central obesity rate, and clinical obesity rate were higher among urban school students compared to rural school students, with all differences being statistically significant(P&lt;0.05). The general obesity rate was higher in boys than in girls(P&lt;0.05), while no statistically significant difference was observed in central obesity rate between genders. The obesity rate was higher in the 7-11-year-old group than in the 12-17-year-old group, whereas the central obesity rate was lower in the 7-11-year-old group compared to the 12-17-year-old group; both differences were statistically significant(P&lt;0.05). In both boys and girls, a trend of increasing cental obesity rate and dyslipidemia rate was observed with increasing BMI(P&lt;0.05). No association was found between BMI and hypertension.</p><p><strong>Conclusion: </strong>The prevalence of obesity among children and adolescents in the Xinjiang Uygur Autonomous Region shows population-specific differences and is associated with increased health risks.</p>","PeriodicalId":57744,"journal":{"name":"卫生研究","volume":"55 2","pages":"219-224"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}