Feyza Nur Yücel, Semiha Özgüç, Yeliz Bahar-Özdemir, Emre Ata
{"title":"The impact of central sensitization-related symptoms on subacromial steroid injection outcomes in patients with subacromial impingement syndrome: an observational study.","authors":"Feyza Nur Yücel, Semiha Özgüç, Yeliz Bahar-Özdemir, Emre Ata","doi":"10.3344/kjp.24290","DOIUrl":"10.3344/kjp.24290","url":null,"abstract":"<p><strong>Background: </strong>Evidence indicates that central sensitization (CS) plays a role in subacromial impingement syndrome (SIS). Reduced treatment response has been associated with pretreatment pain sensitization features, such as CSrelated symptoms.</p><p><strong>Methods: </strong>Patients who received subacromial steroid injection were evaluated before the injection, at the first and third months. CS-related symptoms were investigated through the central sensitization inventory (CSI), and pain hypersensitivity was investigated by pressure pain threshold (PPT). Patients were evaluated using the visual analog scale (VAS), Quick Disabilities of the Arm, Shoulder, and Hand, Hospital Anxiety and Depression Scale, and Short Form-36.</p><p><strong>Results: </strong>With the injection, all participants had a significant reduction in shoulder pain (<i>P</i> < 0.05). In all follow-ups, VAS values did not differ significantly between the groups, and patients with CSI ≥ 40 had higher levels of disability, anxiety, depression, and worse quality of life before treatment (<i>P</i> < 0.05). Post-injection disability decreased significantly in the CS group and reached similar levels in both groups at the third month (<i>P</i> > 0.05). Although both groups' PPT values were comparable pre-treatment and at the third month, the CS group's affected shoulder showed a notable PPT decline at the first month (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>Pre-treatment CS-related symptoms had no effect on SIS patients' responsiveness to steroid injections.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":" ","pages":"29-42"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characterizing pain in Parkinson's disease: types, predictors, and management implications.","authors":"Ceren Alis, Derya Selcuk Demirelli, Elvin Ay, Gencer Genc","doi":"10.3344/kjp.24245","DOIUrl":"10.3344/kjp.24245","url":null,"abstract":"<p><strong>Background: </strong>Pain impacts quality of life (QoL) in Parkinson's disease (PD) patients, yet it is often overlooked. This study aims to comprehensively evaluate pain in PD, particularly focusing on differences between neuropathic pain (NP) and other types.</p><p><strong>Methods: </strong>We conducted a cross-sectional study involving PD patients, assessing the prevalence and characteristics of pain. Various scales were employed to evaluate anxiety, depression, and QoL. We investigated associations between pain, demographic, and clinical variables to determine predictors and pain-related factors. Additionally, factors related to NP were explored.</p><p><strong>Results: </strong>During the study period, a total of 109 patients were examined. Sixteen patients were excluded due to various reasons. The final analysis included 93 patients (34 females and 59 males). Pain was reported by 80.6% of PD patients, with no significant demographic or clinical differences between those with and without pain. However, longer disease duration predicted NP, and musculoskeletal pain was more prevalent in females. Anxiety was common in patients with central parkinsonian pain (CPP). Patients taking amantadine reported less radicular/ neuropathic pain (RNP), suggesting a therapeutic role.</p><p><strong>Conclusions: </strong>Our findings underscore the high prevalence of pain in PD and its impact on QoL. NP appears to be associated with disease progression, while sex-specific differences highlight the need for personalized pain management strategies. The association between anxiety and CPP emphasizes the importance of addressing psychological factors in PD pain management. Further research on amantadine's benefits in reducing RNP is warranted, emphasizing the importance of tailored pain management strategies for PD patients.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"38 1","pages":"43-50"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In-Ae Song, Joon Hee Lee, Woong Ki Han, Francis Sahngun Nahm
{"title":"The actual duration of spinal cord stimulator use in patients with complex regional pain syndrome: a Korean nationwide cohort study.","authors":"In-Ae Song, Joon Hee Lee, Woong Ki Han, Francis Sahngun Nahm","doi":"10.3344/kjp.24209","DOIUrl":"10.3344/kjp.24209","url":null,"abstract":"<p><strong>Background: </strong>Spinal cord stimulators (SCSs) are used to reduce pain and improve quality of life in patients with complex regional pain syndrome (CRPS). However, many patients opt for device removal after SCS implantation due to diminished effect or complications. There is limited research on the actual duration of SCS use in CRPS patients, and no nationwide population-based studies exist. This study aimed to estimate the real-world duration of SCS use in CRPS patients and examine the influencing factors on the duration of SCS use by analyzing the National Healthcare Insurance Database.</p><p><strong>Methods: </strong>Adult patients (age ≥ 18) with CRPS who underwent permanent SCS implantation between 2014 and 2021 were included. The authors analyzed the median duration of SCS implantation and evaluated the impacts of age, sex, hospital type, and insurance type.</p><p><strong>Results: </strong>Of 408 potential patients, 373 patients were included. The median duration of SCS use was 4.4 (95% confidence interval [CI]: 4.0-4.8) years. Male patients retained SCSs longer than female patients (4.7 vs . 4.0 years, <i>P</i> = 0.014), and veterans' healthcare beneficiaries showed the longest duration of SCS use (median 6.9 [95% CI: 4.6-7.8] years). Age and hospital type did not affect the duration of SCS use (<i>P</i> = 0.381 and <i>P</i> = 0.122, respectively).</p><p><strong>Conclusions: </strong>The median SCS use duration in CRPS patients was 4.4 years. Considering the high cost and invasiveness of SCS, patients should be informed about the expected duration of SCS use, alongside potential risks and benefits.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":" ","pages":"51-57"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Data sharing and research integrity: lessons from a recent retraction.","authors":"Francis Sahngun Nahm","doi":"10.3344/kjp.24391","DOIUrl":"10.3344/kjp.24391","url":null,"abstract":"","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"38 1","pages":"1-3"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seungeun Choi, Taeyup Kim, Hae Kyeong Yoo, Sang-Youn Park, Soo-Hyuk Yoon, Ho-Jin Lee
{"title":"Validation of the Korean version of defense and veterans pain rating scale for assessment of postoperative pain: a prospective observational cohort study.","authors":"Seungeun Choi, Taeyup Kim, Hae Kyeong Yoo, Sang-Youn Park, Soo-Hyuk Yoon, Ho-Jin Lee","doi":"10.3344/kjp.24346","DOIUrl":"10.3344/kjp.24346","url":null,"abstract":"<p><strong>Background: </strong>The defense and veterans pain rating scale (DVPRS) is a pain assessment tool combining a numerical rating scale (NRS) with descriptive words, colors, and facial expressions. This study aimed to validate the Korean version of the DVPRS (K-DVPRS) for postoperative pain assessment.</p><p><strong>Methods: </strong>This study included patients who underwent elective laparoscopic or robotic abdominal surgery. The original DVPRS was translated into Korean using a forward-backward method. Pain intensities at rest and during coughing were assessed at 24 and 48 hours postoperatively using the NRS and K-DVPRS, respectively. The EuroQol 5-Dimension 5-Level (EQ-5D-5L) questionnaire was also used. The validity, reliability, and responsiveness of the K-DVPRS were evaluated.</p><p><strong>Results: </strong>Of the 174 patients screened, 150 were enrolled, and 148 completed the study. The K-DVPRS had strong convergent validity with the NRS at 24 and 48 hours postoperatively (ρ: 0.75 to 0.78, all <i>P</i> < 0.001). Construct validity was confirmed by significant differences in pain scores based on surgical extent and duration. The internal consistency was acceptable (Cronbach's alpha: 0.77 and 0.85 at 24 and 48 hours, respectively), and test-retest reliability at 24 hours was excellent (intraclass correlation coefficient: 0.90 at rest and 0.95 during coughing). Responsiveness, measured by Cliff's effect size, was high from preoperative to 24 hours postoperatively and moderate from 24 to 48 hours. At 48 hours, the K-DVPRS had stronger correlations with the EQ-5D-5L index and EQVAS than with the NRS.</p><p><strong>Conclusions: </strong>The K-DVPRS is a valid, reliable, and responsive tool for assessing postoperative pain in Korean patients.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":" ","pages":"58-68"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142904179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jieun Bae, Yun Hee Lim, Sung Jun Hong, Jae Hun Jeong, Hey Ran Choi, Sun Kyung Park, Jung Eun Kim, Jae Hun Kim
{"title":"Perceptions of treatment, accompanying symptoms, and other problems in patients with chronic pain: a multicenter cross-sectional study in Korea.","authors":"Jieun Bae, Yun Hee Lim, Sung Jun Hong, Jae Hun Jeong, Hey Ran Choi, Sun Kyung Park, Jung Eun Kim, Jae Hun Kim","doi":"10.3344/kjp.24314","DOIUrl":"10.3344/kjp.24314","url":null,"abstract":"<p><strong>Background: </strong>Chronic pain significantly affects daily activities, mental health, and the interpersonal relationships of patients. Consequently, physicians use various treatments to manage pain. This study investigated the perceptions of treatment, accompanying symptoms, and other problems in patients with chronic pain.</p><p><strong>Methods: </strong>The authors enrolled patients with chronic pain from 19 university hospitals in South Korea. Data was collected on age, gender, diagnosis, disease duration, severity of pain, perception of pain treatment, and accompanying symptoms or problems using an anonymous survey comprising 19 questions.</p><p><strong>Results: </strong>In total, 833 patients with chronic pain completed the survey, and 257 (31.0%) and 537 (64.5%) patients expressed concerns about the potential adverse effects of medication and opioid addiction, respectively. Personality changes such as irritability or anger were the most frequent accompanying symptoms in 507 (63.8%) patients, followed by depression and sleep disturbance in 462 (58.1%) and 450 (54.5%) patients, respectively. Depression (<i>P</i> = 0.001) and anxiety (<i>P</i> = 0.029) were more common among women, whereas divorce (<i>P</i> = 0.016), family conflict (<i>P</i> < 0.001), unemployment (<i>P</i> < 0.001), suicide attempts (<i>P</i> < 0.001), and restrictions on economic activity (<i>P</i> < 0.001) were more common among men. The frequency of accompanying symptoms, except for suicidal ideation, was higher in the younger patients aged ≤ 40 years than in the older patients aged > 40 years.</p><p><strong>Conclusions: </strong>Many patients with chronic pain had concerns about adverse effects or medication tolerance and experienced anxiety, depression, or sleep disturbances. The prevalence of accompanying problems varies according to age and gender.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"38 1","pages":"69-78"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nociplastic pain: controversy of the concept.","authors":"Valdas Macionis","doi":"10.3344/kjp.24257","DOIUrl":"10.3344/kjp.24257","url":null,"abstract":"<p><p>Classically, pain can be of a nociceptive or neuropathic nature, which refers to non-neural or neural tissue lesions, respectively. Chronic pain in conditions such as migraine, fibromyalgia, and complex regional pain syndrome (CRPS), is thought to perpetuate without a noxious input. Pain in such patients can be assigned neither to the nociceptive nor neuropathic category. Therefore, a third pain descriptor, named \"nociplastic pain\", has been adopted by the International Association for the Study of Pain. The current controversy-focused narrative review updates littledebated aspects of the new pain concept. The most disputable feature of nociplastic pain is its autonomous persistence, i.e., existence without causative tissue damage, presumably because of a malfunction of pain pathways and processing. This contradicts the fact that nociplastic pain is accompanied by persistent central sensitization that has been shown to require a continuing noxious input, <i>e.g .</i>, nerve injury. Even if sensitization occurs without a lesion, <i>e.g .</i>, in psychogenic and emotional pain, peripheral stimulus is necessary to produce pain. A logical weakness of the concept is that the word \"plastic\" in biology refers to adaptation rather than to maladaptation. The pathophysiologic mechanism of nociplastic pain may, in fact, be associated with background conditions that elude diagnosis because of the limitations of current diagnostic means. Misapplication of the nociplastic pain category may weaken diagnostic alertness toward occult causes of pain. Possible diagnostic errors could be avoided by understanding that nociplastic pain is a mechanism of pain rather than a diagnosis. Clinical use of this pain descriptor deserves a wider critical discussion.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"38 1","pages":"4-13"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of ultrasound-guided ilioinguinal-iliohypogastric nerve block on chronic pain in patients undergoing open inguinal hernia surgery under spinal anesthesia: a randomized double-blind study.","authors":"Rajendra Kumar Sahoo, Amit Pradhan, Priyadarsini Samanta, Laxman Kumar Senapati, Ganesh Chandra Satapathy","doi":"10.3344/kjp.24172","DOIUrl":"10.3344/kjp.24172","url":null,"abstract":"<p><strong>Background: </strong>Pre-operative ilioinguinal-iliohypogastric nerve block (II-IHNB) has a proven role in lessening acute postoperative pain and opioid consumption following hernia repair. However, its role in preventing post-herniorrhaphy groin pain (PHGP) is still unknown. The current study aims to assess pre-operative II-IHNB's impact on PHGP three and six months after open inguinal hernia repair under spinal anesthesia.</p><p><strong>Methods: </strong>Seventy patients posted for inguinal hernia surgery were randomly allocated into group A (received ultrasound-guided II-IHNB with 10 mL of 0.5% ropivacaine and 4 mg [1 mL] dexamethasone) and group B (received ultrasound-guided II-IHNB with 11 mL of 0.9% normal saline). The time to first analgesic request, pain scores, opioid consumption, DN4 score, and PHGP at 3 and 6 months were analyzed using appropriate statistical tests.</p><p><strong>Results: </strong>The numerical pain rating scale at movement in group A was significantly reduced at all the time intervals of 3, 6, 12, and 24 hours compared to group B. Total opioid usage was lower in group A (3.71 mg [3.90]) <i>versus</i> group B (12.14 mg [4.90]) with a mean difference of -8.43 mg (95% CI -10.54, -6.32), <i>P</i> < 0.001. The time required for the first rescue analgesic was significantly longer in group A (360 min [180-360]) <i>versus</i> (180 min [180-360]) in group B (<i>P</i> < 0.001). However, there was no difference in the incidence of PHGP at three and six months between the two groups.</p><p><strong>Conclusions: </strong>Pre-operative ultrasound-guided II-IHNB reduces postoperative analgesic requirement but does not reduce the incidence of chronic PHGP following hernia surgery at 6 months.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":" ","pages":"332-342"},"PeriodicalIF":3.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}