Korean Journal of Pain最新文献

{"title":"Association between fatty infiltration in the cervical multifidus and treatment response following cervical interlaminar epidural steroid injection.","authors":"Hyun-Jung Kwon,&nbsp;Chan-Sik Kim,&nbsp;Sungwon Kim,&nbsp;Syn Hae Yoon,&nbsp;Jungho Koh,&nbsp;Young Ki Kim,&nbsp;Seong-Soo Choi,&nbsp;Jin-Woo Shin,&nbsp;Doo-Hwan Kim","doi":"10.3344/kjp.23092","DOIUrl":"https://doi.org/10.3344/kjp.23092","url":null,"abstract":"<p><strong>Background: </strong>Recent attention has been directed towards fatty infiltration in the cervical extensor muscles for predicting clinical outcomes in several cervical disorders. This study aimed to investigate the potential association between fatty infiltration in the cervical multifidus and treatment response following cervical interlaminar epidural steroid injection (CIESI) in patients with cervical radicular pain.</p><p><strong>Methods: </strong>The data of patients with cervical radicular pain who received CIESIs between March 2021 and June 2022 were reviewed. A responder was defined as a patient with a numerical rating scale decrease of ≥ 50% from the baseline to three months after the procedure. The presence of fatty infiltration in the cervical multifidus was assessed, along with patient characteristics, and cervical spine disease severity. To assess cervical sarcopenia, fatty infiltration in the bilateral multifidus muscles was evaluated at the C5-C6 level using the Goutallier classification.</p><p><strong>Results: </strong>Among 275 included patients, 113 (41.1%) and 162 (58.9%) were classified as non-responders and responders, respectively. The age, severity of disc degeneration, and grade of cervical multifidus fatty degeneration were significantly lower in responders. Multivariate logistic regression analysis revealed that pre-procedural symptoms (radicular pain with neck pain, odd ratio [OR] = 0.527, <i>P</i> = 0.024) and high-grade cervical multifidus fatty degeneration (Goutallier grade 2.5-4, OR = 0.320, <i>P</i> = 0.005) were significantly associated with an unsuccessful response to CIESI.</p><p><strong>Conclusions: </strong>These results suggest high-grade cervical multifidus fatty infiltration is an independent predictor of poor response to CIESI in patients with cervical radicular pain.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"36 3","pages":"358-368"},"PeriodicalIF":2.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5b/42/kjp-36-3-358.PMC10322661.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10119578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Household catastrophic health expenditure related to pain in Korea.","authors":"Sun Mi Shin","doi":"10.3344/kjp.23041","DOIUrl":"https://doi.org/10.3344/kjp.23041","url":null,"abstract":"<p><strong>Background: </strong>The data related to pain and catastrophic health expenditure (CHE) needed to be further explored. This study aims to understand the relationship between pain and CHE.</p><p><strong>Methods: </strong>Using cross-sectional analysis of 4-year data (2015-2018) from the Korea Health Panel, the prevalence of CHE and adjusted odds ratio (AOR) by pain type were confirmed.</p><p><strong>Results: </strong>Among participants (n = 46,597), the prevalence of pain and severe pain were 24.2% and 1.1%, respectively. The use of medical services in emergency rooms, hospitalizations, and outpatients increased in the order of pain-free, pain, and severe pain (<i>P</i> < 0.001). Prevalence of household CHE was 3.3% vs. 11.1% vs. 25.9%, (<i>P</i> < 0.001). The AOR of CHE was 1.5 (95% confidence interval [CI], 1.4-1.7) for pain and 3.1 (95% CI, 2.5-3.9) for severe pain. Household capacity to pay per year was lower and lower in the order of pain-free, pain, and severe pain ($25,094 vs. $17,965 vs. $14,056, <i>P</i> < 0.001). Also, the household out-of-pocket expenditure per year was higher and higher in the order of pain-free, pain, and severe pain ($1,649, $1,870, $2,331, <i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>It can be inferred that pain is one of the mechanisms of poverty. Positivist healthcare policies for the prevention and management of pain should be sought.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"36 3","pages":"347-357"},"PeriodicalIF":2.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/49/b9/kjp-36-3-347.PMC10322657.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9750979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the existence of and a block technique for the inferior lateral genicular nerve: cadaveric study.","authors":"Jiyoung Kim,&nbsp;Ji Yeong Kim,&nbsp;Hwa Yong Shin,&nbsp;Sung Eun Sim,&nbsp;Siwook Chung,&nbsp;Youngjae Jeon,&nbsp;Sang Hyun Kim,&nbsp;Jong Min Jeong,&nbsp;Jieun Kim,&nbsp;U-Young Lee,&nbsp;Hue Jung Park","doi":"10.3344/kjp.23112","DOIUrl":"https://doi.org/10.3344/kjp.23112","url":null,"abstract":"<p><strong>Background: </strong>Among the four genicular nerves innervating the anterior aspect of the knee, the inferior lateral genicular nerve has been omitted as a target of blocking. Some authors have suggested that the inferior lateral genicular nerve of the knee might pass beneath the lateral collateral ligament of knee. The authors aimed to study the location of the inferior lateral genicular nerve and the spread of injectate during the inferior lateral genicular nerve block.</p><p><strong>Methods: </strong>In ten knees from fresh frozen cadavers, the authors performed on each an ultrasound-guided block of the inferior lateral genicular nerve of the knee just below the lateral collateral ligament. The needle was inserted below the lateral collateral ligament, and 2 mL of blue dye was injected. A week later, the cadavers were dissected, and the existence of the inferior lateral genicular nerve and the spread of dye around it was investigated.</p><p><strong>Results: </strong>The proportion of inferior lateral genicular nerves branching from the common peroneal nerve was found in 8 of 10 (80.0%) cadavers. Of these eight cadavers with inferior lateral genicular nerve, five specimens (62.5%) were stained with blue dye. The common peroneal nerve was not infiltrated with dye in any specimens.</p><p><strong>Conclusions: </strong>When 2 mL of dye was inserted inferiorly to the lateral collateral ligament, the inferior lateral genicular nerve could be blocked in 62.5% of specimens. Because the common peroneal nerve was not involved in any specimen, motor weakness would be avoided with this method.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"36 3","pages":"328-334"},"PeriodicalIF":2.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bc/1d/kjp-36-3-328.PMC10322663.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10137204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P value, it is just not enough","authors":"B. Hong","doi":"10.3344/kjp.23173.","DOIUrl":"https://doi.org/10.3344/kjp.23173.","url":null,"abstract":"1. Govil N, Parag K, Arora P, Khandelwal H, Singh A; Ruchi. Perioperative duloxetine as part of a multimodal analgesia regime reduces postoperative pain in lumbar canal stenosis surgery: a randomized, triple blind, and placebocontrolled trial. Korean J Pain 2020; 33: 40-7. 2. Mostafa MF, Aal FAA, Ali IH, Ibrahim AK, Herdan R. Dexmedetomidine during suprazygomatic maxillary nerve block for pediatric cleft palate repair, randomized double-blind controlled study. Korean J Pain 2020; 33: 81-9. 3. Ahuja V, Thapa D, Chander A, Gombar S, Gupta R, Gupta S. Role of dexmedetomidine as adjuvant in postoperative sciatic popliteal and adductor canal analgesia in trauma patients: a randomized controlled trial. Korean J Pain 2020; 33: 166-75. 4. Şahiner Y, Yağan Ö, Akdağlı Ekici A, Ekici M, Demir E. The effect of atropine in preventing catheter-related pain and discomfort in patients undergoing transurethral resection due to bladder tumor; prospective randomized, controlled study. Korean J Pain 2020; 33: 176-82. 5. Cankurtaran D, Karaahmet OZ, Yildiz SY, Eksioglu E, Dulgeroglu D, Unlu E. Comparing the effectiveness of ultraSupplementary Table 1. Reporting of effect size and confidence interval (CI) in 23 randomized controlled studies published in the Korean Journal of Pain from January 2020 to April 2023","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"36 1","pages":"269 - 271"},"PeriodicalIF":2.8,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48311703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antisense oligodeoxynucleotides against dynamin-related protein 1 reduce remifentanil-induced hyperalgesia by modulating spinal N-methyl-D-aspartate receptor expression in rats","authors":"Songyi Zhou, Yizhao Pan, Yan Zhang, Lijun Gu, Leikai Ma, Qing-Qing Xu, Weijian Wang, Jiehao Sun","doi":"10.7910/DVN/EJ82IJ.","DOIUrl":"https://doi.org/10.7910/DVN/EJ82IJ.","url":null,"abstract":"Background Spinal N-methyl-D-aspartate (NMDA) receptor activation is attributed to remifentanil-induced hyperalgesia (RIH). However, the specific mechanism and subsequent treatment is still unknown. Previous studies have shown that the dynamin-related protein 1 (DRP1)-mitochondria-reactive oxygen species (ROS) pathway plays an important role in neuropathic pain. This study examined whether antisense oligodeoxynucleotides against DRP1 (AS-DRP1) could reverse RIH. Methods The authors first measured changes in paw withdrawal mechanical threshold (PWMT) and paw withdrawal thermal latency (PWTL) at 24 hours before remifentanil infusion and 4, 8, 24, and 48 hours after infusion. The expression levels of DRP1 and NR2B were measured after behavioral testing using Western blotting. In addition, DRP1 expression was knocked down by intrathecal administration of AS-DRP1 to investigate the effects of DRP1 on RIH. The behavioral testing, the expression levels of spinal DRP1 and NR2B, and dorsal mitochondrial superoxide were measured. Changes in mitochondrial morphology were assessed using electron microscopy. Results After remifentanil exposure, upregulation of spinal DRP1 and NR2B was observed along with a reduction in PWMT and PWTL. In addition, AS-DRP1 improved RIH-induced PWTL and PWMT (P < 0.001 and P < 0.001) and reduced remifentanil-mediated enhancement of spinal DRP1 and NR2B expression (P = 0.020 and P = 0.022). More importantly, AS-DRP1 reversed RIH-induced mitochondrial fission (P = 0.020) and mitochondrial superoxide upregulation (P = 0.031). Conclusions These results indicate that AS-DRP1 could modulate NMDA receptor expression to prevent RIH through the DRP1-mitochondria-ROS pathway.","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"36 1","pages":"316 - 327"},"PeriodicalIF":2.8,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42314069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuropathic pain feature in cancer-induced bone pain: does it matter? a prospective observational study.","authors":"Nantthasorn Zinboonyahgoon,&nbsp;Choopong Luansritisakul","doi":"10.3344/kjp.22392","DOIUrl":"https://doi.org/10.3344/kjp.22392","url":null,"abstract":"<p><strong>Background: </strong>Cancer-induced bone pain (CIBP) is considered to have both nociceptive and neuropathic components. However, the prevalence, risk factors, and impact of the neuropathic components are yet poorly understood.</p><p><strong>Methods: </strong>We estimate the prevalence of neuropathic pain (NP) features in patients with CIBP at a tertiary care pain clinic setting using the Douleur Neuropathique 4 questionnaire and evaluate their associated factors and their impact after 4 weeks of treatment using the Brief Pain Inventory questionnaire and the Edmonton Symptom Assessment System.</p><p><strong>Results: </strong>A total of 133 patients were recruited. The estimated prevalence of NP was 30.8% (95% confidence interval: 23.6%-39.1%). Initially, the patients with NP had significantly higher average pain scores (6.00 vs. 5.05, <i>P</i> = 0.006), higher total interference scores (5.84 vs. 4.89, <i>P</i> = 0.033), and symptom distress scores (35.88 vs. 26.52, <i>P</i> = 0.002). After 4 weeks of treatment, patients in both groups reported significantly decreased pain intensity and improved quality of life. However, the patients with NP still reported significantly higher average pain (4.61 vs. 3.58, <i>P</i> = 0.048), trending toward higher total interference scores (3.52 vs. 2.99, <i>P</i> = 0.426), and symptom distress scores (23.30 vs. 20.77, <i>P</i> = 0.524). From multivariate analysis, the independent risk factors for NP were younger age, pain in the extremities, and higher average pain scores.</p><p><strong>Conclusions: </strong>NP are common in patients with CIBP. These conditions negatively affect pain intensity and the patient's quality of life before and after treatment.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"36 2","pages":"253-267"},"PeriodicalIF":2.8,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/13/0a/kjp-36-2-253.PMC10043784.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9227877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of three different exercise trainings in patients with chronic neck pain: a randomized controlled study.","authors":"Besta Hazal Gumuscu,&nbsp;Eylul Pinar Kisa,&nbsp;Begum Kara Kaya,&nbsp;Rasmi Muammer","doi":"10.3344/kjp.22371","DOIUrl":"https://doi.org/10.3344/kjp.22371","url":null,"abstract":"<p><strong>Background: </strong>Neck pain is a common problem in the general population and second only to low back pain in musculoskeletal problems. The aim of this study is to compare three different types of exercise training in patients with chronic neck pain.</p><p><strong>Methods: </strong>This study was conducted on 45 patients with neck pain. Patients were divided into 3 groups: Group 1 (conventional treatment), Group 2 (conventional treatment plus deep cervical flexor training), and Group 3 (conventional treatment plus stabilization of the neck and core region). The exercise programs were applied for four weeks, three days a week. The demographic data, pain intensity (verbal numeric pain scale), posture (Reedco's posture scale), cervical range of motion ([ROM] goniometer), and disability (Neck Disability Index [NDI]) were evaluated.</p><p><strong>Results: </strong>In all groups, a significant improvement was found in terms of pain, posture, ROM, and NDI values in all groups (<i>P</i> < 0.001). Between the groups, analyses showed that the pain and posture improved more in Group 3, while the ROM and NDI improved more in Group 2.</p><p><strong>Conclusions: </strong>In addition to conventional treatment, applying core stabilization exercises or deep cervical flexor muscle training to patients with neck pain may be more effective in reducing pain and disability and increasing ROM than conventional treatment alone.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"36 2","pages":"242-252"},"PeriodicalIF":2.8,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b9/15/kjp-36-2-242.PMC10043788.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9196237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term consistency of clinical sensory testing measures for pain assessment.","authors":"Pablo Bellosta-López,&nbsp;Víctor Doménech-García,&nbsp;Thorvaldur Skuli Palsson,&nbsp;Pablo Herrero,&nbsp;Steffan Wittrup Mcphee Christensen","doi":"10.3344/kjp.23011","DOIUrl":"https://doi.org/10.3344/kjp.23011","url":null,"abstract":"<p><strong>Background: </strong>Understanding the stability of quantitative sensory tests (QSTs) over time is important to aid clinicians in selecting a battery of tests for assessing and monitoring patients. This study evaluated the short- and long-term reliability of selected QSTs.</p><p><strong>Methods: </strong>Twenty healthy women participated in three experimental sessions: Baseline, 2 weeks, and 6 months. Measurements included pressure pain thresholds (PPT) in the neck, upper back, and leg; Pressure-cuff pain tolerance around the upper-arm; conditioned pain modulation during a pressure-cuff stimulus; and referred pain following a suprathreshold pressure stimulation. Intraclass correlation coefficients (ICC) and minimum detectable change (MDC) were calculated.</p><p><strong>Results: </strong>Reliability for PPT was excellent for all sites at 2 weeks (ICC, 0.96-0.99; MDC, 22-55 kPa) and from good to excellent at 6 months (ICC, 0.88-0.95; MDC, 47-91 kPa). ICC for pressure-cuff pain tolerance indicated excellent reliability at both times (0.91-0.97). For conditioned pain modulation, reliability was moderate for all sites at 2 weeks (ICC, 0.57-0.74; MDC, 24%-35%), while it was moderate at the neck (ICC, 0.54; MDC, 27%) and poor at the upper back and leg at 6 months. ICC for referred pain areas was excellent at 2 weeks (0.90) and good at 6 months (0.86).</p><p><strong>Conclusions: </strong>PPT, pressure pain tolerance, and pressure-induced referred pain should be considered reliable procedures to assess the pain-sensory profile over time. In contrast, conditioned pain modulation was shown to be unstable. Future studies prospectively analyzing the pain-sensory profile will be able to better calculate appropriate sample sizes.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"36 2","pages":"173-183"},"PeriodicalIF":2.8,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0f/70/kjp-36-2-173.PMC10043786.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9227876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The analgesic effect of programmed cell death protein-1.","authors":"Jong Yeon Park","doi":"10.3344/kjp.23082","DOIUrl":"https://doi.org/10.3344/kjp.23082","url":null,"abstract":"mental research paper about the heparanase and cancer pain progression was presented [1]. Heparanase treatment aggravated mechanical allodynia, cold response, and spontaneous pain. Additionally, the contents of inflammatory cytokines (TNF-α, NF-κB, IL-1β, and IL-6) was increased, and programmed death-ligand 1 (PD-L1) level was decreased in tumor tissue. Inversely, the heparanase inhibitor (SST0001) exhibited opposite results [1]. Programmed cell death protein 1, also known as PD-1, is a type I transmembrane glycoprotein and a cell surface receptor. PD-1 is broadly presented on cytotoxic T cells, regulatory T cells, B cells, natural killer cells, microglia, macrophages, and certain types of neurons [2–4]. PD-1 has a role in suppressing the inflammatory actions of T cells. Therefore, the immune system is downregulated, self-tolerance is promoted, autoimmune diseases are attenuated, and killing actions against cancer cells by the immune system could be prevented [5]. PD-1 is an essential and negatively acting regulator related to diverse biological effects and diseases, such as cancer immunotherapy, brain tumors, Alzheimer’s disease, stroke, multiple sclerosis and cognitive dysfunctions [6,7]. PD-1 signaling modulates synaptic plasticity, synaptic transmission, and neuronal excitability in neurons [2]. The neuronal signaling of PD-1 regulates pain by modulating dephosphorylating transient receptor potential subtype V1 (TRPV1) [8], GABAergic neurotransmission [4], and sodium/potassium channels [3]. In an experiment with Pd1 knockout mice, Pd1 knockout mice were more sensitive to pain stimulation than wild type mice, and it presented that PD-1 performs a crucial role in the modulation of pain [3]. Additionally, the activation of PD-1 signaling by PD-L1 is related to the regulations of μ-opioid receptor signals in the nociceptive neurons, and it enhances the antinociceptive actions of morphine [9]. Therefore, small molecular peptides targeting PD-1 could be an alternative medicine for treating chronic pain. On the other hand, PD-1 inhibitors, a newly developed class of anticancer medicine that block PD-1, could activate the immune system to attack cancer cells and could be used to treat special types of cancers [5]. For example, Pembrolizumab is a humanized IgG4 isotype antibody, and it blocks a protective mechanism of cancer cells and allows the immune system to destroy cancer cells. It targets the PD-1 receptor of lymphocytes and acts by targeting the cellular pathway of proteins, known as PD-1/PDL1, found on the immune cells and certain cancer cells. Pembrolizumab is used as an immunotherapy medicine","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"36 2","pages":"147-148"},"PeriodicalIF":2.8,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/5f/kjp-36-2-147.PMC10043789.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9234577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of chronic pain and contributing factors: a cross-sectional population-based study among 2,379 Iranian adolescents.","authors":"Maryam Shaygan,&nbsp;Azita Jaberi,&nbsp;Marziehsadat Razavizadegan,&nbsp;Zainab Shayegan","doi":"10.3344/kjp.22336","DOIUrl":"https://doi.org/10.3344/kjp.22336","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to determine the prevalence of chronic pain and its contributing factors among teenagers aged 12-21 years in Shiraz, Iran.</p><p><strong>Methods: </strong>This cross-sectional study was conducted on adolescents aged 12-21 years. Demographic variables of the adolescents and their parents as well as the pain characteristics were assessed. Descriptive statistics, multinomial logistic regression, and regression models were used to describe the characteristics of the pain and its predictive factors.</p><p><strong>Results: </strong>The prevalence of chronic pain was 23.7%. The results revealed no significant difference between the male and female participants regarding the pain characteristics, except for the home medications used for pain relief. The results of a chi-square test showed that the mother's pain, education, and occupation, and the father's education were associated significantly with chronic pain in adolescents (<i>P</i> < 0.05). Multinomial logistic regression also showed the mother's history of pain played a significant role in the incidence of adolescents' chronic pain.</p><p><strong>Conclusions: </strong>The prevalence of chronic pain was relatively high in these adolescents. The results also provided basic and essential information about the contributing factors in this area. However, consideration of factors such as anxiety, depression, school problems, sleep, and physical activity are suggested in future longitudinal studies.</p>","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"36 2","pages":"230-241"},"PeriodicalIF":2.8,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/48/b2/kjp-36-2-230.PMC10043785.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9234580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}