Trends in the prescription of opioids and gabapentinoids in patients with failed back surgery syndrome in Korea: a population-based study.

IF 3.4 3区医学 Q2 CLINICAL NEUROLOGY

Korean Journal of Pain Pub Date : 2024-01-01 Epub Date: 2023-12-22 DOI:10.3344/kjp.23246

Jinyoung Oh, Jinseok Yeo

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引用次数: 0

Abstract

Background: Failed back surgery syndrome (FBSS) is a chronic condition that is characterized by persistent back pain following one or more spinal surgeries. Pharmacological interventions, such as the use of opioids and gabapentinoids, are frequently used in the treatment of FBSS. However, prolonged and excessive use of these medications can lead to dependence and adverse effects. This study investigates trends in opioid and gabapentinoid prescriptions among patients with FBSS in Korea from 2016 to 2020.

Methods: Data from the Health Insurance and Review Agency were analyzed, and claims listing FBSS were selected for the study. Prescription patterns of opioids and gabapentinoids were classified based on the number of days prescribed per year.

Results: Of the 390,095 patients diagnosed with FBSS, 41.6% of the patients were prescribed gabapentinoids, and 42.0% of them were prescribed opioids, while 10.6% of the patients were classified as long-term gabapentinoid users, 11.4% as long-term opioid users, and 7.4% of the patients were found to have long-term prescriptions for both drugs. The proportion of patients who received both gabapentinoid and opioid prescriptions increased annually. The doses of opioids prescribed have also increased along with the increase in the number of patients receiving opioid prescriptions.

Conclusions: The prescription rates of opioids and gabapentinoids among patients with FBSS in Korea continue to increase steadily, posing potential risks of addiction and adverse effects. Further research is needed to better understand the actual status of addiction in patients with FBSS.

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韩国背部手术失败综合征患者阿片类药物和加巴喷丁类药物的处方趋势：一项基于人群的研究。

背景：：背部手术失败综合征（FBSS）是一种慢性疾病，其特征是在一次或多次脊柱手术后出现持续性背部疼痛。阿片类药物和加巴喷丁类药物等药物干预措施常用于治疗 FBSS。然而，长期和过度使用这些药物会导致依赖性和不良反应。本研究调查了 2016 年至 2020 年韩国 FBSS 患者阿片类药物和加巴喷丁类药物的处方趋势：分析了健康保险和审查局的数据，并选择了列出 FBSS 的索赔作为研究对象。根据每年的处方天数对阿片类药物和加巴喷丁类药物的处方模式进行分类：在390,095名确诊为FBSS的患者中，41.6%的患者被处方加巴喷丁类药物，42.0%的患者被处方阿片类药物，10.6%的患者被归类为加巴喷丁类药物长期使用者，11.4%的患者被归类为阿片类药物长期使用者，7.4%的患者被发现同时长期处方两种药物。同时接受加巴喷丁诺类和阿片类药物处方的患者比例逐年增加。阿片类药物的处方剂量也随着阿片类药物处方患者人数的增加而增加：结论：在韩国，FBSS 患者的阿片类药物和加巴喷丁类药物处方率继续稳步上升，带来了成瘾和不良反应的潜在风险。要更好地了解 FBSS 患者成瘾的实际情况，还需要进一步的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Korean Journal of Pain Medicine-Anesthesiology and Pain Medicine

CiteScore

5.40

自引率

7.10%

发文量

审稿时长

16 weeks

期刊介绍： Korean Journal of Pain (Korean J Pain, KJP) is the official journal of the Korean Pain Society, founded in 1986. It has been published since 1988. It publishes peer reviewed original articles related to all aspects of pain, including clinical and basic research, patient care, education, and health policy. It has been published quarterly in English since 2009 (on the first day of January, April, July, and October). In addition, it has also become the official journal of the International Spinal Pain Society since 2016. The mission of the Journal is to improve the care of patients in pain by providing a forum for clinical researchers, basic scientists, clinicians, and other health professionals. The circulation number per issue is 50.