Journals of Gerontology Series B-Psychological Sciences and Social Sciences最新文献

{"title":"Longitudinal trajectories of psychological resilience and cognitive impairment among older adults: Evidence from a national cohort study.","authors":"Peicheng Wang, Ruihua Li, Yanhua Chen","doi":"10.1093/geronb/gbaf035","DOIUrl":"https://doi.org/10.1093/geronb/gbaf035","url":null,"abstract":"<p><strong>Objectives: </strong>The relationship between resilience trajectories and cognitive health is not well understood. This study aimed to identify clusters of psychological resilience trajectories in a national sample of older adults and to examine the association with cognitive impairment over time.</p><p><strong>Methods: </strong>This study used data from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) from 2008 to 2018, and 2,788 respondents were included in this prospective analysis. Using a group-based trajectory modeling approach, we identified resilience trajectory groups over a 6-year period. Cox proportional hazards models were used to assess the relationship between the resilience trajectory groups and cognitive impairment.</p><p><strong>Results: </strong>Three distinct trajectories of psychological resilience, including decreasing resilience group (n=131, 4.7%), persistent middle resilience group (n=1,808, 64.8%), and persistent high resilience group (n=849, 30.5%). During the 6-year follow-up, compared to those with persistent high resilience, participants with persistent middle resilience (HR=1.40, 95%CI=1.11-1.75) and decreasing resilience (HR=2.31, 95%CI=1.65-3.23) remained consistently associated with a higher risk of cognitive impairment. The associations between resilience trajectories and cognitive impairment varied by lifestyle and health conditions.</p><p><strong>Discussion: </strong>Psychological resilience is a relatively stable trait among older adults in China, with most individuals maintaining a persistently high or middle level of resilience throughout the follow-up period; however, declining psychological resilience was significantly associated with the risk of cognitive impairment. Therefore, developing targeted interventions to strengthen psychological resilience in older adults is crucial for promoting cognitive health and successful aging.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racial-Ethnic Differences in Care Networks of Older Adults: Empirical Exploration of Possible Explanations.","authors":"Zhiyong Lin","doi":"10.1093/geronb/gbaf038","DOIUrl":"https://doi.org/10.1093/geronb/gbaf038","url":null,"abstract":"<p><strong>Objectives: </strong>Previous research on eldercare among minority populations often highlights the role of values, beliefs, and social expectations, placing greater emphasis on ideational factors than on sociostructural and health factors in explaining racial-ethnic differences in care arrangements. This study aims to describe the extent to which care received by older adults varies by race-ethnicity and to explore possible explanations for these variations using the behavioral model of health care use.</p><p><strong>Methods: </strong>Data were sourced from the 2018 National Health and Aging Trends Study (NHATS), a nationally representative survey of Medicare beneficiaries aged 68 and older. Latent class analyses were used to develop a care network typology with combinations of care from different sources. Multinomial regression models assessed various predisposing, enabling, and need factors associated with racial-ethnic differences in the distribution of constructed care network types. Formal mediation analysis tested potential mediators of these differences.</p><p><strong>Results: </strong>Black and Hispanic older adults tended to receive care from children and extended kin caregivers, while White older adults were more likely to receive care from their spouses and perform self-care with assistive technologies. Mediation analyses revealed that racial-ethnic differences in care networks were primarily attributable to enabling factors, including family configurations, social networks, and socioeconomic status. Limited evidence was found for the roles of predisposing factors, measured by care preferences, and need factors, measured by health conditions, in explaining these differences.</p><p><strong>Discussion: </strong>The findings highlight the need for more research and policy interventions to address the diverse challenges faced by socially disadvantaged older adults.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between social engagement frequency and the risk of depression in South Korea, the US, and the UK: Multinational evidence from longitudinal studies of aging.","authors":"Jaehyeong Cho, Tae Hyeon Kim, Jiyeon Oh, Sooji Lee, Kyeongeun Kim, Jaeyu Park, Hyesu Jo, Yi Deun Jeong, Seoyoung Park, Yejun Son, Nicola Veronese, Guillermo F López Sánchez, Louis Jacob, Selin Woo, Dong Keon Yon, Lee Smith","doi":"10.1093/geronb/gbaf036","DOIUrl":"https://doi.org/10.1093/geronb/gbaf036","url":null,"abstract":"<p><strong>Background: </strong>While greater social engagement is often associated with a reduced risk of depression, longitudinal studies that account for diverse social structures and cultural contexts among middle-aged or older are limited.</p><p><strong>Methods: </strong>This study utilized cohort data from the Korean Longitudinal Study of Ageing (n=11,174; 2006-2020) in South Korea (KR), the Health and Retirement Study (n=42,405; 2004-2019) in the US, and the English Longitudinal Study of Ageing (n=28,624; 2002-2019) in the UK, including a total of 29,378 individuals from the population aged ≥45 years. Social engagement frequency was categorized into infrequent, intermediate, and frequent, with changes classified as unchanged, increased, or decreased. The primary outcome was the onset of depression, assessed using the CES-D Scale. Hazard ratios (HR) and 95% confidence intervals (CI) were estimated using a Cox proportional hazards regression model.</p><p><strong>Results: </strong>In the KR cohort, increased social engagement significantly reduced depression risk only in the infrequent group (KR: HR, 0.20 [95% CI, 0.14-0.28]). However, decreased social engagement elevated depression risk in both the intermediate group (KR: 6.92 [3.73-12.83]; US: 1.44 [1.16-1.79]) and the frequent group (KR: 1.50 [1.30-1.74]; US: 1.24 [1.13-1.38]). Conversely, in the UK cohort, increased social engagement raised depression risk in the infrequent group (UK: 1.35 [1.01-1.79]) and intermediate group (UK: 1.63 [1.17-2.27]), while decreased engagement lowered depression risk only in the frequent group (UK: 0.80 [0.71-0.90]).</p><p><strong>Discussion: </strong>We observed notable national variations in the association between social engagement and depression risk, influenced by cultural and political differences.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Offspring Educational Disadvantage and Parents' Dementia Onset: Does the Educational Success of One Child Moderate the Educational Disadvantage of Another?","authors":"Jenjira J Yahirun, Jaycob S Applegate, Krysia N Mossakowski, Mark D Hayward","doi":"10.1093/geronb/gbaf033","DOIUrl":"https://doi.org/10.1093/geronb/gbaf033","url":null,"abstract":"<p><strong>Objectives: </strong>A growing body of research examines how adult children's education influences older parents' cognitive health. Whereas prior studies tend to focus on educational advantage, this study seeks to understand how various measures of educational disadvantage are associated with parents' dementia likelihood. In addition, we ask how the risks associated with one child's educational disadvantage are shaped by a sibling's educational success.</p><p><strong>Methods: </strong>Using data from the U.S. Health and Retirement Study (2000-2018) and event history analyses, comparisons are made between measures of offspring educational disadvantage and their relationships with parents' risk of dementia onset. In addition, analyses are conducted to understand whether the link between one child's educational disadvantage and parental dementia onset is influenced by a sibling's educational advantage.</p><p><strong>Results: </strong>Educational disadvantage is associated with an increased risk of parental dementia onset, with a threshold measure for whether a parent had at least one child without a high school education providing the best model fit for the data. Moreover, the heightened risks associated with one child's educational disadvantage are not offset by another sibling's educational success.</p><p><strong>Discussion: </strong>Children's educational deficits are a hidden source of health disparities among older parents. Although scholars in recent years have rightly focused on the importance of offspring education, more attention should be paid to conceptualizing how educational disadvantage matters for parents and how the educational attainment of each child shapes parents' cognitive health.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intergenerational Coresidence with Children and Grandchildren and Maternal Sleep Duration at Mid-life.","authors":"Rui Cao, Rin Reczek, Mieke Beth Thomeer","doi":"10.1093/geronb/gbaf034","DOIUrl":"https://doi.org/10.1093/geronb/gbaf034","url":null,"abstract":"<p><strong>Objectives: </strong>Mothers with young children tend to have shorter sleep durations than childfree women, but previous research has not considered heterogeneity in sleep duration among mid-life mothers who have varying coresidential patterns with their adult, minor, and grandchildren. We examine distribution of sleep duration across mothers' different intergenerational coresidential contexts (living without any children, living with any minor children, living with only adult children, and living with any grandchildren) and test how these patterns differ across racial/ethnic groups.</p><p><strong>Methods: </strong>Regression analyses estimate sleep duration among a sample of mid-life mothers with minor and adult children and grandchildren from the National Longitudinal Survey of Youth 1979 (NLSY79) data (N=3,300). Moderation analyses consider differences across racial/ethnic groups (non-Hispanic White, non-Hispanic Black, Hispanic).</p><p><strong>Results: </strong>Relative to the mothers with no coresiding children or grandchildren, mothers with coresiding minor or adult children reported less sleep. However, this gap varies across racial/ethnic groups; specifically, the lower sleep duration for mothers with coresidential children is only significant for White and Black mothers, not Hispanic mothers.</p><p><strong>Discussion: </strong>Sleep is a critical health indicator across the life course and a contributor to other health outcomes later in life. Thus, it is important to identify whose sleep is most vulnerable-especially in mid-life when sleep trajectories are the groundwork for later-life well-being. We demonstrate the importance of coresidential status with adult and minor children and grandchildren on the sleep of mothers in mid-life, drawing specific attention to the differences across racial/ethnic groups.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Loneliness links Adverse Childhood Experiences to Mortality Risk across 26 years.","authors":"Aisling Curtis, Emma Kirwan, Martina Luchetti, Ann-Marie Creaven, Nicholas Turiano, Máire McGeehan, Eileen K Graham, Páraic S O'Súilleabháin","doi":"10.1093/geronb/gbaf016","DOIUrl":"https://doi.org/10.1093/geronb/gbaf016","url":null,"abstract":"<p><strong>Objectives: </strong>Adverse Childhood Experiences (ACEs) are associated with increased mortality risk. Individuals with a history of certain adversity during childhood tend to report higher levels of loneliness in later life. In our pre-registered study, we examined whether loneliness mediates the ACEs to mortality risk relation.</p><p><strong>Methods: </strong>Participants were from the Midlife in the United States Survey (N = 4963; M [SD] 46.44 [12.52] years, 53.3% female). Follow-up period spanned 26 years. A comprehensive measure of ACEs was employed consisting of 20 ACEs from five categories: physical abuse, emotional abuse, socioeconomic disadvantage, adverse family structure, and poor health at age 16 years.</p><p><strong>Results: </strong>ACEs was a significant predictor of mortality risk. Loneliness mediated the ACEs-mortality risk relation. In other words, loneliness in adulthood accounted for the relation between ACEs and future death. These effects withstood a range of sensitivity checks and adjustments for important factors, such as social isolation.</p><p><strong>Discussion: </strong>Loneliness appears to be a central mechanism in the long-term impact of ACEs on longevity, such that, for adversity during childhood, loneliness experienced during adulthood may be a toxic pathway to future death.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overconfidence and Financial Risk Tolerance in Older Age.","authors":"Colleen C Frank, Gary R Mottola, Meiru Chen, Lei Yu, Patricia A Boyle, Gregory R Samanez-Larkin, Kendra L Seaman","doi":"10.1093/geronb/gbaf032","DOIUrl":"https://doi.org/10.1093/geronb/gbaf032","url":null,"abstract":"<p><strong>Objectives: </strong>Excessive financial risk taking in older age can have harmful consequences as opportunities to recover lost wealth are limited. Understanding financial risk taking in older age is important for identifying vulnerabilities and developing interventions to empower aging investors to make wise financial choices. In this paper, we explore how overconfidence in financial knowledge affects financial risk-taking among older adults.</p><p><strong>Methods: </strong>We examine this research question in older adults aged 58-101 (N = 1242) using data from the Rush Memory and Aging Project (MAP).</p><p><strong>Results: </strong>After controlling for demographics, overconfidence was associated with self-reported financial risk tolerance such that those who were more overconfident reported tolerating more financial risks. Moreover, this relationship emerged for both healthy older adults and those diagnosed with mild cognitive impairment (MCI). However, overconfidence did not predict performance on a behavioral measure of risk aversion.</p><p><strong>Discussion: </strong>The present results suggest that overconfidence may partially contribute to financial risk-taking in older adults, regardless of cognitive status. Thus, interventions aimed at calibrating confidence to actual levels of financial knowledge could be an impactful target for intervention.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Machine Learning and Environmental and Genetic Risk Factors for the Early Detection of Preclinical Alzheimer's Disease.","authors":"Noor Al-Hammadi, Mahmoud Abouelyazid, David C Brown, Pooja Lalwani, Hannes Devos, David B Carr, Ganesh M Babulal","doi":"10.1093/geronb/gbaf023","DOIUrl":"https://doi.org/10.1093/geronb/gbaf023","url":null,"abstract":"<p><strong>Objective: </strong>This study classified preclinical Alzheimer's disease (AD) using cognitive screening, neighborhood deprivation via the Area Deprivation Index (ADI), and sociodemographic and genetic risk factors. Additionally, it compared the predictive accuracy of multiple machine learning algorithms and examined model performance with two bootstrapping procedures.</p><p><strong>Methods: </strong>Data were drawn from a longitudinal cohort that required participants to be age 65 or older, cognitively normal at baseline, and active drivers, defined as taking at least one trip a week. Naturalistic driving data were collected using a commercial datalogger. Biomarker positivity was determined via amyloid pathology using cerebrospinal fluid and positron emission tomography imaging. ADI was captured based on geocoding latitude and longitude to derive a national ranking for the specific location (home or unique destination). Machine learning algorithms classified preclinical AD. Each individual model's predictive ability was confirmed in a 20% testing dataset with 100 rounds of resampling with and without replacement.</p><p><strong>Results: </strong>Among 292 participants (n = 2,792 observations), including ADI of trip destinations, participants' home ADI, and frequency of trips to the same ADI led to a slight but notable improvement in predicting preclinical AD. The ensemble model demonstrated superior predictive performance, highlighting the potential of integrating multiple models for early AD detection.</p><p><strong>Discussion: </strong>Our findings underscore the importance of incorporating socioeconomic and environmental variables, such as neighborhood deprivation, in predicting preclinical AD. Addressing socioeconomic disparities through public health strategies is crucial for mitigating AD risk and enhancing the quality of life for older adults.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How often and why do people manage their emotions in older adulthood?","authors":"Tabea Springstein, Tammy English","doi":"10.1093/geronb/gbaf031","DOIUrl":"https://doi.org/10.1093/geronb/gbaf031","url":null,"abstract":"<p><strong>Objectives: </strong>Prominent theories of adult development suggest individuals increasingly prioritize emotional goals and social relationships as they age. Accordingly, older adults are expected to invest more in maintaining their emotional well-being compared to younger adults. Prior work suggests older adults may accomplish this goal by structuring their lives in ways that reduce the need to actively manage unwanted emotion. We tested the hypotheses that (1) older adults regulate their emotions less often in daily life compared to younger adults, and (2) when emotion regulation occurs, older adults are more motivated than younger adults by pro-hedonic and social concerns.</p><p><strong>Method: </strong>Using experience sampling (7x/day for 9 days), we assessed emotion regulation frequency and motives in younger adults (n=75), cognitively normal older adults (n=93), and older adults with mild cognitive impairment (MCI; n=63).</p><p><strong>Results: </strong>Emotion regulation was less frequent for older adults with MCI (16%) and without MCI (18%) compared to younger adults (43%), even when controlling for emotional experience. However, few differences in emotion regulation motives emerged and they were not robust to controlling for age group differences in emotion.</p><p><strong>Discussion: </strong>These findings extend previous work on emotion regulation in aging, which largely has focused on strategies, by documenting age differences in how often, but not why, people regulate. Future work is needed to explore how age-related differences in life contexts might result in less need for emotion regulation in older adults. Conserving effort directed towards emotion regulation could be particularly beneficial among older adults with more limited cognitive resources.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computational phenotyping of cognitive decline with retest learning.","authors":"Zita Oravecz, Joachim Vandekerckhove, Jonathan G Hakun, Sharon H Kim, Mindy J Katz, Cuiling Wang, Richard B Lipton, Carol A Derby, Nelson A Roque, Martin J Sliwinski","doi":"10.1093/geronb/gbaf030","DOIUrl":"https://doi.org/10.1093/geronb/gbaf030","url":null,"abstract":"<p><strong>Objectives: </strong>Cognitive change is a complex phenomenon encompassing both retest-related performance gains and potential cognitive decline. Disentangling these dynamics is necessary for effective tracking of subtle cognitive change and risk factors for Alzheimer's Disease and Related Dementias (ADRD).</p><p><strong>Method: </strong>We applied a computational cognitive model of learning and forgetting to data from Einstein Aging Study (EAS; n = 316). EAS participants completed multiple bursts of ultra-brief, high-frequency cognitive assessments on smartphones. Analyzing response time data from a measure of visual short-term working memory, the Color Shapes task, and from a measure of processing speed, the Symbol Search task, we extracted several key cognitive markers: short-term intraindividual variability in performance, within-burst retest learning and asymptotic (peak) performance, across-burst change in asymptote and forgetting of retest gains.</p><p><strong>Results: </strong>Asymptotic performance was related to both mild cognitive impairment (MCI) and age, and there was evidence of asymptotic slowing over time. Long-term forgetting, learning rate, and within-person variability uniquely signified MCI, irrespective of age.</p><p><strong>Discussion: </strong>Computational cognitive markers hold promise as sensitive and specific indicators of preclinical cognitive change, aiding risk identification and targeted interventions.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}