Neuroscience and Biobehavioral Reviews最新文献_第3页

The role of enteric nervous system and GDNF in depression: Conversation between the brain and the gut 肠道神经系统和 GDNF 在抑郁症中的作用：大脑与肠道之间的对话。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-10-23 DOI: 10.1016/j.neubiorev.2024.105931

Chuoyi Liang , Sijia Wei , Yelin Ji , Jiayi Lin , Wenli Jiao , Zhiying Li , Fengxia Yan , Xi Jing

{"title":"The role of enteric nervous system and GDNF in depression: Conversation between the brain and the gut","authors":"Chuoyi Liang , Sijia Wei , Yelin Ji , Jiayi Lin , Wenli Jiao , Zhiying Li , Fengxia Yan , Xi Jing","doi":"10.1016/j.neubiorev.2024.105931","DOIUrl":"10.1016/j.neubiorev.2024.105931","url":null,"abstract":"<div><div>Depression is a debilitating mental disorder that causes a persistent feeling of sadness and loss of interest. Approximately 280 million individuals worldwide suffer from depression by 2023. Despite the heavy medical and social burden imposed by depression, pathophysiology remains incompletely understood. Emerging evidence indicates various bidirectional interplay enable communication between the gut and brain. These interplays provide a link between intestinal and central nervous system as well as feedback from cortical and sensory centers to enteric activities, which also influences physiology and behavior in depression. This review aims to overview the significant role of the enteric nervous system (ENS) in the pathophysiology of depression and gut-brain axis’s contribution to depressive disorders. Additionally, we explore the alterations in enteric glia cells (EGCs) and glial cell line-derived neurotrophic factor (GDNF) in depression and their involvement in neuronal support, intestinal homeostasis maintains and immune response activation. Modulating ENS function, EGCs and GDNF level could serve as novel strategies for future antidepressant therapy.</div></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":"167 ","pages":"Article 105931"},"PeriodicalIF":7.5,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postmortem findings of organ damage in novel psychoactive substances users: A comprehensive review 新型精神活性物质使用者器官损伤的尸检结果：综述。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-10-22 DOI: 10.1016/j.neubiorev.2024.105927

Beatrice Benedetti , Celeste Conte , Eva Bergamin , Riccardo Di Santo , Gabriele Ciasca , John M. Corkery , Marta Bassi , Giorgia Corli , Sabrine Bilel , Fabrizio Schifano , Matteo Marti , Fabio De-Giorgio

{"title":"Postmortem findings of organ damage in novel psychoactive substances users: A comprehensive review","authors":"Beatrice Benedetti , Celeste Conte , Eva Bergamin , Riccardo Di Santo , Gabriele Ciasca , John M. Corkery , Marta Bassi , Giorgia Corli , Sabrine Bilel , Fabrizio Schifano , Matteo Marti , Fabio De-Giorgio","doi":"10.1016/j.neubiorev.2024.105927","DOIUrl":"10.1016/j.neubiorev.2024.105927","url":null,"abstract":"<div><h3>Introduction</h3><div>Despite the rising number of NPS-related deaths, comprehensive data on their prevalence, identification, and associated organ damage remain scarce.</div></div><div><h3>Materials and methods</h3><div>A literature search was conducted. Predefined inclusion and exclusion criteria were applied, resulting in the identification of 197 articles.</div></div><div><h3>Results</h3><div>We identified 446 cases of NPS-related deaths, involving a total of 176 different substances. Synthetic opioids were the most prevalent class (34 %), followed by synthetic cannabinoids (22 %) and cathinones (21 %). Co-ingestion of NPS with other substances occurred in 77 % of cases. Macroscopic findings varied across organs, with congestion and edema most observed in the brain (23 %) and lung (56 %), respectively.</div></div><div><h3>Discussion</h3><div>The existing literature lacks comprehensive descriptions of organs subjected to autopsy and histological examination in NPS-positive subjects. Despite this limitation, our findings underscore the prominence of lung pathology. Moreover, the prevalence of normal organs in cases of acute intoxication is a significant observation. We advocate for future research to provide more detailed insights to enhance our understanding of the multifaceted landscape of NPS-related deaths.</div></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":"167 ","pages":"Article 105927"},"PeriodicalIF":7.5,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Charting the neuroscience of interpersonal trust: A bibliographic literature review 描绘人际信任的神经科学：文献综述。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-10-20 DOI: 10.1016/j.neubiorev.2024.105930

Yan Wu , Frank Krueger

{"title":"Charting the neuroscience of interpersonal trust: A bibliographic literature review","authors":"Yan Wu , Frank Krueger","doi":"10.1016/j.neubiorev.2024.105930","DOIUrl":"10.1016/j.neubiorev.2024.105930","url":null,"abstract":"<div><div>Interpersonal trust is essential for societal well-being, underpinning relationships from individuals to institutions. Neuroscience research on trust has advanced swiftly since 2001. While quantitative reviews, meta-analyses, and theoretical frameworks have effectively synthesized trust neuroscience research, bibliometric analysis remains underutilized. Our bibliometric analysis aimed to provide a comprehensive overview of trust neuroscience's current state and future directions by examining its historical development, key contributors, geographic distribution, methodological paradigms, influential works, thematic trends, and overall impact. This field has been characterized by the input of a few key contributors through international collaboration, with significant contributions from the U.S., China, the Netherlands, and Germany. Research predominantly utilizes the trust game and fMRI, with a rising focus on neural networks, general trust, and differentiating behavioral from attitudinal trust. Integrating insights from psychology, economics, and sociology, this interdisciplinary field holds promise for advancing our understanding of trust through a neurobiological lens. In conclusion, our bibliographic literature review provides valuable insights and guidance for scholars, spotlighting potential avenues for further investigation in this fast-growing field.</div></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":"167 ","pages":"Article 105930"},"PeriodicalIF":7.5,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic and meta-analytic review of the impact of sleep restriction on memory formation 关于睡眠限制对记忆形成的影响的系统性和荟萃分析综述。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-10-19 DOI: 10.1016/j.neubiorev.2024.105929

Rebecca Crowley , Eleanor Alderman , Amir-Homayoun Javadi , Jakke Tamminen

{"title":"A systematic and meta-analytic review of the impact of sleep restriction on memory formation","authors":"Rebecca Crowley , Eleanor Alderman , Amir-Homayoun Javadi , Jakke Tamminen","doi":"10.1016/j.neubiorev.2024.105929","DOIUrl":"10.1016/j.neubiorev.2024.105929","url":null,"abstract":"<div><div>Modern life causes a quarter of adults and half of teenagers to sleep for less than is recommended (Kocevska et al., 2021). Given well-documented benefits of sleep on memory, we must understand the cognitive costs of short sleep. We analysed 125 sleep restriction effect sizes from 39 reports involving 1234 participants. Restricting sleep (3–6.5 hours) compared to normal sleep (7–11 hours) negatively affects memory formation with a small effect size (Hedges’ <em>g</em> = 0.29, 95 % CI = [0.13, 0.44]). We detected no evidence for publication bias. When sleep restriction effect sizes were compared with 185 sleep deprivation effect sizes (Newbury et al., 2021) no statistically significant difference was found, suggesting that missing some sleep has similar consequences for memory as not sleeping at all. When the analysis was restricted to post-encoding, rather than pre-encoding, sleep loss, sleep deprivation was associated with larger memory impairment than restriction. Our findings are best accounted for by the sequential hypothesis which emphasises complementary roles of slow-wave sleep and REM sleep for memory.</div></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":"167 ","pages":"Article 105929"},"PeriodicalIF":7.5,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of the locus coeruleus-noradrenergic system in stress-related psychopathology and resilience: Clinical and pre-clinical evidences 脑室-去甲肾上腺素能系统在压力相关精神病理学和复原力中的作用：临床和临床前证据。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-10-18 DOI: 10.1016/j.neubiorev.2024.105925

Déa Slavova , Vanesa Ortiz , Maud Blaise , Marya Bairachnaya , Bruno Giros , Elsa Isingrini

{"title":"Role of the locus coeruleus-noradrenergic system in stress-related psychopathology and resilience: Clinical and pre-clinical evidences","authors":"Déa Slavova , Vanesa Ortiz , Maud Blaise , Marya Bairachnaya , Bruno Giros , Elsa Isingrini","doi":"10.1016/j.neubiorev.2024.105925","DOIUrl":"10.1016/j.neubiorev.2024.105925","url":null,"abstract":"<div><div>Stressful events, from daily stressors to traumatic experiences, are common and occur at any age. Despite the high prevalence of trauma, not everyone develops stress-related disorders like major depressive disorder (MDD) and post-traumatic stress disorder (PTSD), a variation attributed to resilience, the ability to adapt and avoid negative consequences of significant stress. This review examines the locus coeruleus-norepinephrine (LC-NE) system, a critical component in the brain's stress response. It discusses the LC-NE system's anatomical and functional complexity and its role in individual variability in stress responses. How different etiological factors and stress modalities affect the LC-NE system, influencing both adaptive stress responses and psychopathologies, are discussed and supported by evidence from human and animal studies. It also explores molecular and cellular adaptations in the LC that contribute to resilience, including roles of neuropeptide, inflammatory cytokines, and genetic modulation, and addresses developmental and sex differences in stress vulnerability. The need for a multifaceted approach to understand stress-induced psychopathologies is emphasized and pave the way for more personalized interventions for stress-related disorders.</div></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":"167 ","pages":"Article 105925"},"PeriodicalIF":7.5,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between self-reported interoception and anxiety: A systematic review and meta-analysis 自我感知与焦虑之间的关系：系统回顾与元分析》。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-10-18 DOI: 10.1016/j.neubiorev.2024.105923

Rhea Clemente , Amanda Murphy , Jennifer Murphy

{"title":"The relationship between self-reported interoception and anxiety: A systematic review and meta-analysis","authors":"Rhea Clemente , Amanda Murphy , Jennifer Murphy","doi":"10.1016/j.neubiorev.2024.105923","DOIUrl":"10.1016/j.neubiorev.2024.105923","url":null,"abstract":"<div><div>Interoception, the processing of internal bodily sensations, is associated with various mental health conditions. In particular, anxiety is often considered to be the prototypical interoceptive disorder. However, empirical evidence is mixed, with meta-analytic work reporting no relationship between anxiety and cardiac interoceptive accuracy. Less explored, however, are the mixed results relating to anxiety and self-reported interoception. This meta-analysis of 71 studies explored the relationship between self-report measures of interoception and anxiety. Across 12 measures (20 subscales), anxiety was associated with increased negative evaluations of, frequency of, and sensitivity to, bodily signals. Anxiety was also associated with greater (negative) attention to bodily signals, and difficulties describing bodily signals and emotions. However, anxiety was not associated with the use of bodily signals to inform emotions (e.g., noticing emotionally induced bodily signals). Results are discussed considering the overlap between anxiety and interoception questionnaires, the lack of specificity of certain measures, and the potential confound of individual differences in questionnaire interpretation. We also discuss limitations of anxiety measures and the clinical relevance of findings.</div></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":"167 ","pages":"Article 105923"},"PeriodicalIF":7.5,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toward neuroscientific understanding in posttraumatic growth: Scoping review identifying electrophysiological neurofeedback training targets for brain-based research 创伤后成长中的神经科学理解：为基于大脑的研究确定电生理神经反馈训练目标的范围审查。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-10-18 DOI: 10.1016/j.neubiorev.2024.105926

AJ Glazebrook , Jane Shakespeare-Finch , Brooke Andrew , Johan van der Meer

{"title":"Toward neuroscientific understanding in posttraumatic growth: Scoping review identifying electrophysiological neurofeedback training targets for brain-based research","authors":"AJ Glazebrook , Jane Shakespeare-Finch , Brooke Andrew , Johan van der Meer","doi":"10.1016/j.neubiorev.2024.105926","DOIUrl":"10.1016/j.neubiorev.2024.105926","url":null,"abstract":"<div><div>Improved neural understanding of posttraumatic growth (PTG) is required for effective trauma care. PTG is the advantageous psychological change some individuals derive from their struggle to overcome trauma. This comprehensive review critically examined the limited neural PTG research, to identify electrophysiological training targets for future research examining neurofeedback to enhance PTG, and provides novel insights into the emerging neural theory of PTG. PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) informed the process. Findings from the studies <em>N</em>=8 (participants <em>N</em>=765) revealed PTG was correlated with left-lateralised alpha frequency power patterns. Specifically, PTG was associated with lower left frontal alpha power, higher left central alpha power, and lower parietal alpha power. Differences between studies may identify different components of PTG-related neural circuitry, or represent variations in PTG and sub-factor strength, mechanistic differences between studies, or the potential confounding presence of posttraumatic stress disorder (PTSD). While lower alpha power has been associated with higher PTSD in existing literature, higher left central alpha power was associated with lower PTSD. Therefore, alpha upregulation neurofeedback delivered over the sensorimotor cortices of the brain, around left central EEG electrode C3, presented the most promising neurofeedback target.</div></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":"167 ","pages":"Article 105926"},"PeriodicalIF":7.5,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From prodromal stages to clinical trials: The promise of digital speech biomarkers in Parkinson's disease 从前驱期到临床试验：帕金森病数字语音生物标记的前景。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-10-18 DOI: 10.1016/j.neubiorev.2024.105922

Jan Rusz , Paul Krack , Elina Tripoliti

{"title":"From prodromal stages to clinical trials: The promise of digital speech biomarkers in Parkinson's disease","authors":"Jan Rusz , Paul Krack , Elina Tripoliti","doi":"10.1016/j.neubiorev.2024.105922","DOIUrl":"10.1016/j.neubiorev.2024.105922","url":null,"abstract":"<div><div>Speech impairment is a common and disabling symptom in Parkinson's disease (PD), affecting communication and quality of life. Advances in digital speech processing and artificial intelligence have revolutionized objective speech analysis. Given the complex nature of speech impairment, acoustic speech analysis offers unique biomarkers for neuroprotective treatments from the prodromal stages of PD. Digital speech biomarkers can monitor levodopa-induced motor complications, detect the effects of deep brain stimulation, and provide feedback for behavioral speech therapy. This review updates the mechanisms underlying speech impairment, the impact of speech phenotypes, and the effects of interventions on speech. We evaluate the strengths, potential weaknesses, and suitability of promising digital speech biomarkers in PD for capturing disease progression and treatment efficacy. Additionally, we explore the translational potential of PD speech biomarkers to other neuropsychiatric diseases, offering insights into motion, cognition, and emotion. Finally, we highlight knowledge gaps and suggest directions for future research to enhance the use of quantitative speech measures in disease-modifying clinical trials. The findings demonstrate that one year is sufficient to detect disease progression in early PD through speech biomarkers. Voice quality, pitch, loudness, and articulation measures appear to capture the efficacy of treatment interventions most effectively. Certain speech features, such as loudness and articulation rate, behave oppositely in different neurological diseases, offering valuable insights for differential diagnosis. In conclusion, this review highlights speech as a biomarker in tracking disease progression, especially in the prodromal stages of PD, and calls for further longitudinal studies to establish its efficacy across diverse populations.</div></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":"167 ","pages":"Article 105922"},"PeriodicalIF":7.5,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain and cognition: The need for a broader biological perspective to overcome old biases 大脑与认知：需要更广泛的生物学视角来克服旧的偏见。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-10-18 DOI: 10.1016/j.neubiorev.2024.105928

Jiří Dvořáček , Dalibor Kodrík

{"title":"Brain and cognition: The need for a broader biological perspective to overcome old biases","authors":"Jiří Dvořáček , Dalibor Kodrík","doi":"10.1016/j.neubiorev.2024.105928","DOIUrl":"10.1016/j.neubiorev.2024.105928","url":null,"abstract":"<div><div>Even with accumulating knowledge, no consensus regarding the understanding of intelligence or cognition exists, and the universal brain bases for these functions remain unclear. Traditionally, our understanding of cognition is based on self-evident principles that appear indisputable when looking only at our species; however, this can distance us from understanding its essence (anthropocentrism, corticocentrism, intellectocentrism, neurocentrism, and idea of orthogenesis of brain evolution). Herein, we use several examples from biology to demonstrate the usefulness of comparative ways of thinking in relativizing these biases. We discuss the relationship between the number of neurons and cognition and draw attention to the highly developed cognitive performance of animals with small brains, to some \"tricks\" of evolution, to how animals cope with small hardware, to some animals with high-quality brains with an alternative architecture to vertebrates, and to surprising basal cognitive skills in aneural, unicellular organisms. Cognition can be supplemented by the idea of a multicellular organism as a continuum, with many levels of cognitive function, including the possible basal learning in single cells.</div></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":"167 ","pages":"Article 105928"},"PeriodicalIF":7.5,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival in a world of complex dangers 在充满复杂危险的世界中生存。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-10-16 DOI: 10.1016/j.neubiorev.2024.105924

Dean Mobbs , Toby Wise , Sarah Tashjian , JiaJin Zhang , Karl Friston , Drew Headley

{"title":"Survival in a world of complex dangers","authors":"Dean Mobbs , Toby Wise , Sarah Tashjian , JiaJin Zhang , Karl Friston , Drew Headley","doi":"10.1016/j.neubiorev.2024.105924","DOIUrl":"10.1016/j.neubiorev.2024.105924","url":null,"abstract":"<div><div>How did our nomadic ancestors continually adapt to the seemingly limitless and unpredictable number of dangers in the natural world? We argue that human defensive behaviors are dynamically constructed to facilitate survival in capricious and itinerant environments. We first hypothesize that internal and external states result in state constructions that combine to form a meta-representation. When a threat is detected, it triggers the action construction. Action constructions are formed through two contiguous survival strategies: generalization strategies, which are used when encountering new threats and ecologies. Generalization strategies are associated with cognitive representations that have high dimensionality and which furnish flexible psychological constructs, including relations between threats, and imagination, and which converge through the construction of defensive states. We posit that generalization strategies drive ‘explorative’ behaviors including information seeking, where the goal is to increase knowledge that can be used to mitigate current and future threats. Conversely, specialization strategies entail lower dimensional representations, which underpin specialized, sometimes reflexive, or habitual survival behaviors that are ‘exploitative’. Together, these strategies capture a central adaptive feature of human survival systems: self-preservation in response to a myriad of threats.</div></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":"167 ","pages":"Article 105924"},"PeriodicalIF":7.5,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0