Neuroscience and Biobehavioral Reviews最新文献

Childhood maltreatment as a predictor of substance use/misuse among youth: A systematic review and meta-analysis. 童年虐待是青少年使用/滥用药物的预测因素：系统回顾和荟萃分析。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-09-05 DOI: 10.1016/j.neubiorev.2024.105873

Coral Rakovski, Mikayla Lalli, Jessica Gu, Madison Hobson, Bianca Wollenhaupt-Aguiar, Luciano Minuzzi, Flavio Kapczinski, Taiane de Azevedo Cardoso, Benicio N Frey

{"title":"Childhood maltreatment as a predictor of substance use/misuse among youth: A systematic review and meta-analysis.","authors":"Coral Rakovski, Mikayla Lalli, Jessica Gu, Madison Hobson, Bianca Wollenhaupt-Aguiar, Luciano Minuzzi, Flavio Kapczinski, Taiane de Azevedo Cardoso, Benicio N Frey","doi":"10.1016/j.neubiorev.2024.105873","DOIUrl":"https://doi.org/10.1016/j.neubiorev.2024.105873","url":null,"abstract":"<p><p>This systematic review and meta-analysis aimed to comprehensively describe whether experiencing a variety of childhood maltreatment types predicts a variety of substance use/misuse types among youth, beyond the narrow scope covered in previous systematic reviews on similar topics. A literature search was conducted in June, 2022 using PubMed, PsycInfo, and Embase. 58 studies (total participant n=170,749) were included. These studies were primarily organized by substance type outcomes including alcohol (n=43), cannabis (n=25), unspecified substances (n=25), and other specific substances (n=10). Results were further stratified by maltreatment type. For specific maltreatment and substance type combinations, the majority of studies indicated that childhood maltreatment was a significant predictor of substance use/misuse in youth. Of the 10 meta-analyses we conducted, significant associations were found for the majority (9/10) of maltreatment and substance type combinations. For instance, unspecified childhood maltreatment increased the probability of youth alcohol use by about four times, which was the highest relative risk found. In conclusion, this study shows that childhood maltreatment is a predictor of youth substance use/misuse.</p>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interoception in Pregnancy: Implications for Peripartum Depression. 妊娠期内分泌：对围产期抑郁症的影响。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-09-05 DOI: 10.1016/j.neubiorev.2024.105874

Paul W Savoca, Laura M Glynn, Molly M Fox, Misty C Richards, Bridget L Callaghan

引用次数: 0

Pupillary responses for social versus non-social stimuli in autism: A systematic review and meta-analysis 自闭症患者对社交与非社交刺激的瞳孔反应：系统回顾与荟萃分析。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-09-03 DOI: 10.1016/j.neubiorev.2024.105872

{"title":"Pupillary responses for social versus non-social stimuli in autism: A systematic review and meta-analysis","authors":"","doi":"10.1016/j.neubiorev.2024.105872","DOIUrl":"10.1016/j.neubiorev.2024.105872","url":null,"abstract":"<div><p>Pupillometry has gained attention as a valuable tool for assessing autonomic nervous system activity and studying phasic changes in pupil size to comprehend underlying neurocognitive mechanisms. However, knowledge regarding pupillary responses to social processing in autism is limited. We conducted a systematic review and meta-analysis, examining research studies on pupil size changes that compare social and non-social stimuli in autism. Electronic searches were performed for articles up to September 2023 and relevant studies were evaluated following PRISMA guidelines. Out of 284 articles screened, 14 studies were eligible for systematic review. The results indicated that non-autistic individuals showed larger pupil size for social compared to non-social stimuli (g = 0.54; 95 % CI [0.25, 0.82]), whereas autistic individuals seemed to exhibit no differences between the two conditions. However, high heterogeneity was observed between studies in autistic populations, compromising interpretability. Despite such limitations, pupillary responses may constitute an objective physiological marker of social processing in autism. This review emphasizes the need for further investigations into pupillary responses in autism across different life stages.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adrenocortical deviations and adverse clinical outcomes in children and adolescents exposed to interparental intimate partner violence: A systematic review 遭受父母间亲密伴侣暴力的儿童和青少年的肾上腺皮质偏差和不良临床结果：系统综述。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-09-02 DOI: 10.1016/j.neubiorev.2024.105866

{"title":"Adrenocortical deviations and adverse clinical outcomes in children and adolescents exposed to interparental intimate partner violence: A systematic review","authors":"","doi":"10.1016/j.neubiorev.2024.105866","DOIUrl":"10.1016/j.neubiorev.2024.105866","url":null,"abstract":"<div><p>Childhood exposure to interparental intimate partner violence (i-IPV) is a pervasive form of child maltreatment, posing major public health concerns and elevating risks for enduring adverse clinical and developmental consequences. However, assessing the full spectrum of clinical effects is challenging, potentially leading to inconsistent identification of children in need of early intervention. This systematic review aimed to identify hypothalamic-pituitary-adrenocortical axis dysfunction following i-IPV exposure, elucidating the underlying biopsychobehavioural mechanisms and predicting adverse outcomes. We searched Embase, MEDLINE, and PsycINFO for peer-reviewed studies from infancy through adolescence, screened reference lists and conducted forward searches. Analysis of 23 publications (<em>N</em> = 1848) revealed associations between i-IPV and altered adrenocortical function from early childhood, influenced by FKBP5 haplotype, parental caregiving and offspring emotional insecurity. Results showed that the adrenocortical stress response may predict internalising and externalising problems, childhood asthma, impaired executive function and poor academic performance. Nonetheless, inconsistencies in findings between studies suggest methodological heterogeneity and potential bias. Identifying biomarkers such as cortisol can enhance prediction and mechanism-based intervention efforts but long-term studies with a common theoretical and methodological framework are needed for comprehensive understanding. Integrating biological, emotional, and behavioural assessments could potentiate trauma services and research, ultimately improving outcomes for affected children.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S014976342400335X/pdfft?md5=16c3bedbdfc082d5405134debddda0e2&pid=1-s2.0-S014976342400335X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Commentary on adult and juvenile play in humans and other social primates 评述人类和其他社会灵长类动物的成年和少年游戏。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-08-31 DOI: 10.1016/j.neubiorev.2024.105871

引用次数: 0

Complement 3a induces the synapse loss via C3aR in mitochondria-dependent NLRP3 activating mechanisms during the development and progression of Alzheimer’s disease 在阿尔茨海默病的发生和发展过程中，补体 3a 通过线粒体依赖性 NLRP3 激活机制中的 C3aR 诱导突触丧失。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-08-30 DOI: 10.1016/j.neubiorev.2024.105868

{"title":"Complement 3a induces the synapse loss via C3aR in mitochondria-dependent NLRP3 activating mechanisms during the development and progression of Alzheimer’s disease","authors":"","doi":"10.1016/j.neubiorev.2024.105868","DOIUrl":"10.1016/j.neubiorev.2024.105868","url":null,"abstract":"<div><p>As a central molecule in complement system (CS), complement (C) 3 is upregulated in the patients and animal models of Alzheimer’s disease (AD). C3 will metabolize to iC3b and C3a. iC3b is responsible for clearing β-amyloid protein (Aβ). In this scenario, C3 exerts neuroprotective effects against the disease via iC3b. However, C3a will inhibit microglia to clear the Aβ, leading to the deposition of Aβ and impair the functions of synapses. To their effects on AD, activation of C3a and C3a receptor (C3aR) will impair the mitochondria, leading to the release of reactive oxygen species (ROS), which activates the NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasomes. The overloading of NLRP3 inflammasomes activate microglia, leading to the formation of inflammatory environment. The inflammatory environment will facilitate the deposition of Aβ and abnormal synapse pruning, which results in the progression of AD. Therefore, the current review will decipher the mechanisms of C3a inducing the synapse loss via C3aR in mitochondria-dependent NLRP3 activating mechanisms, which facilitates the understanding the AD.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interoception, network physiology and the emergence of bodily self-awareness 互感、网络生理学和身体自我意识的出现。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-08-30 DOI: 10.1016/j.neubiorev.2024.105864

{"title":"Interoception, network physiology and the emergence of bodily self-awareness","authors":"","doi":"10.1016/j.neubiorev.2024.105864","DOIUrl":"10.1016/j.neubiorev.2024.105864","url":null,"abstract":"<div><p>The interplay between the brain and interoceptive signals is key in maintaining internal balance and orchestrating neural dynamics, encompassing influences on perceptual and self-awareness. Central to this interplay is the differentiation between the external world, others and the self, a cornerstone in the construction of bodily self-awareness. This review synthesizes physiological and behavioral evidence illustrating how interoceptive signals can mediate or influence bodily self-awareness, by encompassing interactions with various sensory modalities. To deepen our understanding of the basis of bodily self-awareness, we propose a network physiology perspective. This approach explores complex neural computations across multiple nodes, shifting the focus from localized areas to large-scale neural networks. It examines how these networks operate in parallel with and adapt to changes in visceral activities. Within this framework, we propose to investigate physiological factors that disrupt bodily self-awareness, emphasizing the impact of interoceptive pathway disruptions, offering insights across several clinical contexts. This integrative perspective not only can enhance the accuracy of mental health assessments but also paves the way for targeted interventions.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424003336/pdfft?md5=dcf80a4ff30ca582e1069d46a4c7eeaf&pid=1-s2.0-S0149763424003336-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatial attention in three-dimensional space: A meta-analysis for the near advantage in target detection and localization 三维空间中的空间注意力：目标检测和定位中近距离优势的元分析。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-08-29 DOI: 10.1016/j.neubiorev.2024.105869

{"title":"Spatial attention in three-dimensional space: A meta-analysis for the near advantage in target detection and localization","authors":"","doi":"10.1016/j.neubiorev.2024.105869","DOIUrl":"10.1016/j.neubiorev.2024.105869","url":null,"abstract":"<div><p>Studies have explored how human spatial attention appears allocated in three-dimensional (3D) space. It has been demonstrated that target distance from the viewer can modulate performance in target detection and localization tasks: reaction times are shorter when targets appear nearer to the observer compared to farther distances (i.e., near advantage). Times have reached to quantitatively analyze this literature. In the current meta-analysis, 29 studies (n = 1260 participants) examined target detection and localization across 3-D space. Moderator analyses included: detection vs localization tasks, spatial cueing vs uncued tasks, control of retinal size across depth, central vs peripheral targets, real-space vs stereoscopic vs monocular depth environments, and inclusion of in-trial motion. The analyses revealed a near advantage for spatial attention that was affected by the moderating variables of controlling for retinal size across depth, the use of spatial cueing tasks, and the inclusion of in-trial motion. Overall, these results provide an up-to-date quantification of the effect of depth and provide insight into methodological differences in evaluating spatial attention.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424003385/pdfft?md5=66e6d1044a63a76e5debf26d1ad2c0df&pid=1-s2.0-S0149763424003385-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of lipid droplets in neurodegenerative diseases: From pathogenesis to therapeutics 脂滴在神经退行性疾病中的作用：从发病机制到治疗方法

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-08-27 DOI: 10.1016/j.neubiorev.2024.105867

{"title":"Role of lipid droplets in neurodegenerative diseases: From pathogenesis to therapeutics","authors":"","doi":"10.1016/j.neubiorev.2024.105867","DOIUrl":"10.1016/j.neubiorev.2024.105867","url":null,"abstract":"<div><p>Neurodegenerative diseases (NDDs) are a series of disorders characterized by the progressive loss of specific neurons, leading to cognitive and locomotor impairment. NDDs affect millions of patients worldwide but lack effective treatments. Dysregulation of lipids, particularly the accumulation of lipid droplets (LDs), is strongly implicated in the pathogenesis of NDDs. How LDs contribute to the occurrence and development of NDDs, and their potential as therapeutic targets remain to be addressed. In present review, we first introduce the processes of LDs formation, transportation and degradation. We then highlight how the accumulation of LDs contributes to the pathogenesis of NDDs in a cell type-specific manner. Moreover, we discuss currently available methods for detecting LDs and elaborate on LDs-based therapeutic strategies for NDDs. Lastly, we identify gaps that need to be filled to better leverage LD-based theranostics in NDDs and other diseases. We hope this review could shed light on the role of LDs in NDDs and facilitate the development of novel therapeutic strategies for NDDs.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424003361/pdfft?md5=2beb34dd61d451f214d9079f652bc67b&pid=1-s2.0-S0149763424003361-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142099067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Real-time fMRI-based neurofeedback to restore brain function in substance use disorders: A systematic review of the literature 基于实时 fMRI 的神经反馈，用于恢复药物使用障碍患者的大脑功能：文献系统回顾。

IF 7.5 1区医学

Neuroscience and Biobehavioral Reviews Pub Date : 2024-08-27 DOI: 10.1016/j.neubiorev.2024.105865

{"title":"Real-time fMRI-based neurofeedback to restore brain function in substance use disorders: A systematic review of the literature","authors":"","doi":"10.1016/j.neubiorev.2024.105865","DOIUrl":"10.1016/j.neubiorev.2024.105865","url":null,"abstract":"<div><h3>Introduction</h3><p>Real-time functional magnetic resonance based-neurofeedback (fMRI-neurofeedback) is a neuromodulation tool where individuals self-modulate brain function based on real-time feedback of their brain activity. fMRI-neurofeedback has been used to target brain dysfunction in substance use disorders (SUDs) and to reduce craving, but a systematic synthesis of up-to-date literature is lacking.</p></div><div><h3>Method</h3><p>Following PRISMA guidelines, we conducted a systematic review of all the literature that examined the effects of fMRI-neurofeedback on individuals with regular psychoactive substance use (PROSPERO pre-registration = CRD42023401137).</p></div><div><h3>Results</h3><p>The literature included 16 studies comprising 446 participants with SUDs involving alcohol, tobacco, and cocaine. There is consistent <em>between-condition</em> (e.g., fMRI-neurofeedback versus control), less consistent <em>pre-to-post</em> fMRI-neurofeedback, and little <em>intervention-by-time</em> effects on brain function in prefrontal-striatal regions and craving.</p></div><div><h3>Conclusion</h3><p>The evidence for changes in brain function/craving was early and inconsistent. More rigorous experiments including repeated measure designs with placebo control conditions, are required to confirm the efficacy of fMRI-neurofeedback in reducing brain alterations and craving in SUDs.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424003348/pdfft?md5=834f476923b080e12c674981a79a33a1&pid=1-s2.0-S0149763424003348-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142094248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0