{"title":"Bohring–Opitz syndrome: Unraveling neonatal hypoglycemia and early detection through whole exome sequencing","authors":"Ching-Ming Lin , Chien-Ming Lin , Sheng-Yuan Ho","doi":"10.1016/j.pedneo.2024.07.001","DOIUrl":"10.1016/j.pedneo.2024.07.001","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141891088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aura María Salazar-Solarte , Laura Torres-Canchala , Frank Carrera-Gil , Diana María Quimbayo-Wilches
{"title":"Pulmonary function and body composition parameters of children with cystic fibrosis from a hight complexity institution between 2015 and 2018","authors":"Aura María Salazar-Solarte , Laura Torres-Canchala , Frank Carrera-Gil , Diana María Quimbayo-Wilches","doi":"10.1016/j.pedneo.2023.11.006","DOIUrl":"10.1016/j.pedneo.2023.11.006","url":null,"abstract":"<div><h3>Background</h3><div>An adequate nutritional status in patients with cystic fibrosis correlates with higher survival and better pulmonary function. Body mass index (BMI) is an anthropometric indicator with independent association with pulmonary function, and it can hide alterations of nutritional status in cystic fibrosis.</div></div><div><h3>Objective</h3><div>To determine the relationship of lung function with BMI and body composition parameters in children with cystic fibrosis in a Hight Complexity institution between 2015 and 2018.</div></div><div><h3>Materials and methods</h3><div>It was an observational study with analytical, cross-sectional, and retrospective scope, including 33 patients between 5 and 17 years old. Spearman's test was applied to evaluate correlation of FEV1 (forced expiratory volume in first second) with BMI and five body composition parameters by bioelectrical impedance using InbodyS10 equipment. Statistical significance was considered with p < 0.05.</div></div><div><h3>Results</h3><div>Positive correlation was obtained between FEV1 and appendicular skeletal muscle mass between lung function and percentage of fat-free mass (p = 0.006) and phase angle (p = 0.001). Percent fat mass had a negative correlation with FEV1 (p = 0.007). BMI and fat free mass index did not correlate with lung function (p = 0.085).</div></div><div><h3>Conclusions</h3><div>Appendicular skeletal muscle mass correlated better than BMI with lung function in children with cystic fibrosis. It is recommended to perform anthropometric follow-up by BMI complemented with body composition study in children with cystic fibrosis. Analyses with larger populations are required to standardize its use.</div></div>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140787799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Priya Das , Subhadeep Saha , Tanu Das , Partha Das , Tamal Basu Roy
{"title":"Confluence of newborn's sex and their mother's characteristics resulting in fetal macrosomia among Indian neonates","authors":"Priya Das , Subhadeep Saha , Tanu Das , Partha Das , Tamal Basu Roy","doi":"10.1016/j.pedneo.2023.11.008","DOIUrl":"10.1016/j.pedneo.2023.11.008","url":null,"abstract":"<div><h3>Background</h3><div>A newborn's birth weight ≥4000 g is defined as fetal macrosomia, which is recognized as a reproductive and serious child health concern.</div></div><div><h3>Objectives</h3><div>Our study aims to reveal existence of any connection between maternal factors and newborn sex in giving birth to newborn ≥4000 g in an Indian context.</div></div><div><h3>Methods</h3><div>Data were drawn from the fifth round of National Family Health Survey (NFHS-5). A cross-sectional observational study was carried out with a total of 152,827 children born to women in reproductive age group (15–49) who had most recent live birth in the five years preceding the survey. Descriptive analyses, cross-tabulation, test of association and multivariate logistic regression analyses were performed.</div></div><div><h3>Results</h3><div>In India, the prevalence of macrosomia was found in 3.8% of the total study participants. Considering newborn characteristics, fetal macrosomia was more prevalent among male neonates than female (AOR: 0.730; 95% CI: 0.687–0.775). Regarding maternal characteristics, overweight (AOR: 1.468; 95% CI: 2.042–2.559) and obese (AOR: 2.764; 95% CI: 2.394–3.192) motherswith gestational diabetes (AOR: 1.731, 95% CI: 1.385–2.164) and hypertension (AOR: 1.288, 95% CI: 1.116–1.488) were more likely to giving birth of macrosomic babies. Multiparous mothers (AOR: 1.207, 95% CI: 1.128–1.293) and women who did not undergo proper antenatal care (ANC) follow up had also greater risk of developing fetal macrosomia. Muslim women (AOR: 1.223, 95% CI: 1.119–1.338), and women belonging to a tribe (AOR: 1.476, 95% CI: 0.922–2.361) were significantly associated with the risk of having newborn ≥4000 g.</div></div><div><h3>Conclusion</h3><div>Emphasis should be given on counseling for mothers for desired weight management before and during pregnancy, gestational diabetes and hypertension screening, physical activity during pregnancy, adequate ANC follow up and balanced dietary intake among pregnant women.</div></div>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140789823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hsiang-Chieh Huang , Shih-Chiang Huang , Yung-Ching Ming , Jin-Yao Lai , Yi-Lun Wang , Tang-Her Jaing
{"title":"Malignant rhabdoid tumor of the urinary bladder in a 1-year and 9-month-old girl: A case report and literature review","authors":"Hsiang-Chieh Huang , Shih-Chiang Huang , Yung-Ching Ming , Jin-Yao Lai , Yi-Lun Wang , Tang-Her Jaing","doi":"10.1016/j.pedneo.2023.12.012","DOIUrl":"10.1016/j.pedneo.2023.12.012","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141602176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fang-Ju Lin, Hsuan-Chang Kuo, Yi-Ywan M. Chen, Chih-Ho Chen
{"title":"Polycyclic annular skin rashes in a patient with streptococcal bacteremia caused by Streptococcus anginosus","authors":"Fang-Ju Lin, Hsuan-Chang Kuo, Yi-Ywan M. Chen, Chih-Ho Chen","doi":"10.1016/j.pedneo.2024.02.011","DOIUrl":"10.1016/j.pedneo.2024.02.011","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142057417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eleonora Fontani , Elena Branda , Marco Denina , Luca Baroero , Carlotta Canavese , Federica Mignone , Pamela Giordano , Margherita Conrieri , Antonia Versace , Claudia Bondone
{"title":"Abducens nerve palsy in a young girl with otorrhea: A case of Gradenigo's syndrome","authors":"Eleonora Fontani , Elena Branda , Marco Denina , Luca Baroero , Carlotta Canavese , Federica Mignone , Pamela Giordano , Margherita Conrieri , Antonia Versace , Claudia Bondone","doi":"10.1016/j.pedneo.2024.06.005","DOIUrl":"10.1016/j.pedneo.2024.06.005","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141617736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Voice treatment of school-aged children with vocal nodules with ABCLOVE rehabilitation","authors":"Yanrui Bian, Jingmiao Wang, Haizhong Zhang, Xiaoyan Yin, Yubo Zhang","doi":"10.1016/j.pedneo.2023.09.015","DOIUrl":"10.1016/j.pedneo.2023.09.015","url":null,"abstract":"<div><h3>Background</h3><div>This study was to explore the effectiveness of the ABCLOVE exercise on school-aged children with vocal nodules after the treatment of budesonide.</div></div><div><h3>Methods</h3><div>Eighty-six school-aged children with vocal nodules were divided into control and ABCLOVE therapy groups. Subjective voice assessment and dysphonia severity index (DSI) assessment were performed before and after the 3-month of therapy.</div></div><div><h3>Results</h3><div>A significant improvement was observed in the ABCLOVE therapy group as compared with the control group (<em>p</em> = 0.035). ABCLOVE therapy significantly reduced the hoarseness and roughness scores in school-aged children with vocal nodules. Additionally, a significant reduction in functional score, physical score, emotional score, and total pVHI score was observed in the ABCLOVE therapy group. Moreover, acoustic parameters including jitter (%) and shimmer (%) were significantly reduced, whereas MPT and DSI were increased in school-aged children with vocal nodules who received 3 months of ABCLOVE treatment.</div></div><div><h3>Conclusion</h3><div>ABCLOVE therapy displayed effectiveness on school-aged children with vocal nodules after the treatment of budesonide.</div></div>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140308025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictive factors of progression to chronic glomerulonephritis in pediatric patients with post streptococcal acute glomerulonephritis","authors":"Ida Ayu Laksmi Arnita Utari , Surya Adhi , Kristia Hermawan , Eggi Arguni","doi":"10.1016/j.pedneo.2023.11.005","DOIUrl":"10.1016/j.pedneo.2023.11.005","url":null,"abstract":"<div><h3>Background</h3><div>Post streptococcal acute glomerulonephritis (PSAGN) patients have favorable prognosis, in which most patients showed full recovery in terms of kidney function. However, there is a slight chance ranging from 3 to 6% that PSAGN patients develop chronic kidney diseasewhich may progress into end-stage kidney disease in later life. It is important to identify the factors that can predict the development of chronic glomerulonephritis following PSAGN. Therefore, early intervention can be performed to halt the progression of chronic kidney disease. This study aimed to determine the predictive factors of chronic glomerulonephritis in pediatric patients with PSAGN.</div></div><div><h3>Methods</h3><div>This study was an analytical observational study with retrospective cohort design. The accessible population was children within the age of 2–18 years old who were admitted with PSAGN between January 2015 and December 2020 in Dr. Sardjito General Hospital Yogyakarta. All anonymized patient data were evaluated for demographic variables, clinical features, laboratory profiles and outcome. Multivariate analysis was performed with multivariate logistic regression method.</div></div><div><h3>Results</h3><div>A total of 124 patients with PSAGN were obtained from medical record data. There were 65 patients (52.4%) with chronic glomerulonephritis. Bivariate analysis was performed on assumed predictive factors with the results indicating massive proteinuria with hypoalbuminemia (OR 1.670, 95%CI 1.199–2.326; <em>p</em> = 0.003), oliguria (OR 1.517, 95%CI 1.101–2.089; <em>p</em> = 0.028) and macroscopic hematuria (OR 1.647, 95%CI:1.061–2.555; <em>p</em> = 0.013) were significantly higher in the PSAGN group with chronic glomerulonephritis compared to those without. Results of the multivariate logistic regression analysis showed massive proteinuria with hypoalbuminemia (OR 2.896, 95%CI 1.177–7.123, <em>p</em> = 0.021) and macroscopic hematuria (OR 2.457, 95%CI ,1.018–5.933, <em>p</em> = 0.046) would highly predict chronic glomerulonephritis in subjects with PSAGN.</div></div><div><h3>Conclusion</h3><div>We concluded that massive proteinuria with hypoalbuminemia and macroscopic hematuria are the predictive factors which highly predict chronic glomerulonephritis in PSAGN.</div></div>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140784208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}