{"title":"Age-related patterns in self-harm and suicide methods among children and adolescents at a medical center in Taiwan.","authors":"Yu-Chin Chen, Ping-Yuan Chen, Chung-Han Ho, Tu-Hsuan Chang","doi":"10.1016/j.pedneo.2025.08.005","DOIUrl":"https://doi.org/10.1016/j.pedneo.2025.08.005","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R Guanà, E Zambaiti, M G Sacco Casamassima, S Garofalo, L Lonati, E Stanton, F Gennari
{"title":"Bilateral pleuropulmonary blastoma in an infant.","authors":"R Guanà, E Zambaiti, M G Sacco Casamassima, S Garofalo, L Lonati, E Stanton, F Gennari","doi":"10.1016/j.pedneo.2025.08.004","DOIUrl":"https://doi.org/10.1016/j.pedneo.2025.08.004","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145180058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Giant Omental Lipoma in a Child.","authors":"Hyun Beak Shin, Yeon Jun Jeong","doi":"10.1016/j.pedneo.2025.08.003","DOIUrl":"https://doi.org/10.1016/j.pedneo.2025.08.003","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing neonatal care through NAVA: A case study on optimizing respiratory support for a very low birth weight infant.","authors":"Daijiro Takahashi, Koko Goto, Kei Goto","doi":"10.1016/j.pedneo.2025.06.006","DOIUrl":"https://doi.org/10.1016/j.pedneo.2025.06.006","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eosinophil count trends during the neonatal period in infants born at 22-24 weeks of gestation compared with infants born at 25-28 weeks: A retrospective longitudinal cohort study.","authors":"Kyosuke Ibi, Naoto Takahashi","doi":"10.1016/j.pedneo.2025.07.003","DOIUrl":"https://doi.org/10.1016/j.pedneo.2025.07.003","url":null,"abstract":"<p><strong>Background: </strong>Eosinophilia is frequently observed in preterm infants. However, little is known about trends in eosinophil counts in periviable infants. This study aimed to describe eosinophil count trends in infants born at 22-24 weeks of gestation during the neonatal period compared with infants born at 25-28 weeks of gestation.</p><p><strong>Methods: </strong>This single-center retrospective cohort study included neonates born between 22 + 0 and 28 + 6 weeks of gestation without congenital anomalies from 2013 to 2022 at our hospital. We described eosinophil count trends in infants born at 22-24 weeks of gestation from birth to 12 weeks of age and compared the trend with those of infants born at 25-28 weeks of gestation. Multiple regression analysis was performed to determine the peak eosinophil counts and potential confounders.</p><p><strong>Results: </strong>A total of 124 infants were analyzed. Eosinophilia (≥700 eosinophils/mm<sup>3</sup>) was observed in 41/42 (97.6 %) infants born at 22-24 weeks of gestation. Eosinophil counts peaked when the infants were 3-4 weeks of age; this trend did not differ from that in infants born at 25-28 weeks of gestation. Peak eosinophil counts were significantly higher in infants born at 22-24 weeks of gestation. Gestational age and birth weight were negatively associated with peak eosinophil counts (Spearman's rank correlation coefficient [r] = -0.23; p = 0.011 and r = -0.30; p < 0.001, respectively). Clinical parameters were not associated with peak eosinophil counts in infants born at 22-24 weeks of gestation after adjusting for gestational age and birth weight.</p><p><strong>Conclusion: </strong>A significantly higher proportion of infants born at 22-24 weeks of gestation exhibited eosinophilia compared to infants born at 25-28 weeks of gestation; however, both groups of infants had similar peak eosinophilia timing. These results will prompt further studies exploring eosinophilia of prematurity mechanism in this population.</p>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William Rozalen, Elana F Pinchefsky, Jessica Gennaoui, Annie Veilleux, Bohdana Marandyuk, Anne-Monique Nuyt, Matsanga Leyila Kaseka, Gregory A Lodygensky, Béatrice Desnous
{"title":"Cerebral palsy predictive value of 4 months-AIMS in newborns with hypoxic-ischaemic encephalopathy.","authors":"William Rozalen, Elana F Pinchefsky, Jessica Gennaoui, Annie Veilleux, Bohdana Marandyuk, Anne-Monique Nuyt, Matsanga Leyila Kaseka, Gregory A Lodygensky, Béatrice Desnous","doi":"10.1016/j.pedneo.2025.08.001","DOIUrl":"https://doi.org/10.1016/j.pedneo.2025.08.001","url":null,"abstract":"<p><strong>Aim: </strong>Predicting motor outcomes in hypoxic-ischaemic encephalopathy (HIE) is challenging. We aimed to assess the value of the four-month Alberta Infant Motor Scale (4M-AIMS) in predicting motor development at 18 months of age.</p><p><strong>Method: </strong>A retrospective cohort study was conducted at Sainte-Justine University Hospital Centre (Canada), including patients with hypoxic-ischemic encephalopathy (HIE) who underwent therapeutic hypothermia between 2009 and 2016. Neurodevelopmental follow-ups were conducted at two and four months with the AIMS, and motor outcomes were classified at 18 months according to the Gross Motor Function Classification System. Ordinal regression was used to assess the predictive value of AIMS scores and brain MRI for motor outcome.</p><p><strong>Results: </strong>Of the 52 newborns included: 16 children (31 %) had normal motor development, 25 (48 %) displayed motor delays, and 11 patients (21 %) had cerebral palsy. Forty-one (79 %) infants had an abnormal 4M-AIMS score (below the 10th percentile). Early brain MRI and 4M-AIMS scores were both predictive of altered motor outcomes (χ<sup>2</sup> = 6.1, p-value = 0.013 and χ<sup>2</sup> = 4.9, p-value = 0.029, respectively). A normal four-month AIMS assessment is considered a reliable indicator for excluding a future cerebral palsy.</p><p><strong>Interpretation: </strong>Complementary assessment with brain MRI and 4M-AIMS with a score below the 0th percentile provides accurate prediction of motor outcomes at 18 months.</p><p><strong>Short title: </strong>Cerebral Palsy predictive value of AIMS.</p>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Weekly vitamin D supplementation during early infancy as a potential strategy to prevent vitamin D insufficiency: A two-center retrospective study.","authors":"Kaori Hara-Isono, Kazumi Morisawa, Mariko Hida, Shintaro Iwamoto, Kazushige Ikeda","doi":"10.1016/j.pedneo.2025.08.002","DOIUrl":"https://doi.org/10.1016/j.pedneo.2025.08.002","url":null,"abstract":"<p><strong>Background: </strong>For preventing Vitamin D (VD) insufficiency, several VD supplementation guidelines were established worldwide. In Japan, no nationwide guidelines for preventing VD insufficiency have been implemented, whereas guidelines for preventing vitamin K (VK) deficiency-related bleeding recommend weekly supplementation of VK. The aim of this study is to clarify whether weekly VD plus VK supplementation during the early neonatal period prevents VD insufficiency at one month of age.</p><p><strong>Methods: </strong>We retrospectively analyzed serum 25-hydroxyvitamin D (25(OH)D) levels of 555 one-month-old infants born between 2017 and 2023. Infants were classified into the control group (not supplemented), weekly group (1000 IU/week), and daily group (240 IU/day). We compared serum 25(OH)D levels among the three groups. Multivariable logistic regression analyses adjusted for formula intake and BMI were performed to better estimate the effect of VD supplementation on the prevention of VD insufficiency.</p><p><strong>Results: </strong>We included 414, 55, and 86 infants in the control, weekly, and daily groups, respectively. All infants received weekly supplementation of VK. Serum 25(OH)D levels in the weekly and daily groups were higher than those in the control group (median (ng/mL): control 9.7 vs weekly 22.2, P < 0.001; control vs daily 23.0, P < 0.001). The frequencies of VD insufficiency were 370/414 (89.4 %), 11/55 (20.0 %), and 22/86 (25.6 %) in the control, weekly, and daily groups, respectively. Adjusted odds ratios of VD insufficiency compared to the control were 0.038 (95 % confidence intervals (95 %CI): 0.017, 0.085) and 0.036 (95 %CI: 0.019, 0.067) in the weekly and daily groups, respectively. No infant with VD excess was observed.</p><p><strong>Conclusion: </strong>Our results demonstrated that combined weekly supplementation of VD and VK during early infancy can prevent VD insufficiency at one month of age without causing VD excess. This finding may provide evidence for the development of nationwide prophylaxis for VD insufficiency in regions lacking specific guidelines.</p>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144862737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring stickler syndrome through a familial case: Beyond Robin sequence.","authors":"Hsin-Ru Wu, Fuu-Jen Tsai","doi":"10.1016/j.pedneo.2025.03.011","DOIUrl":"https://doi.org/10.1016/j.pedneo.2025.03.011","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catarina Freitas, Liliana Teixeira, Ana Cristina Freitas, Luísa Neiva-Araújo
{"title":"Congenital neck mass - What approach?","authors":"Catarina Freitas, Liliana Teixeira, Ana Cristina Freitas, Luísa Neiva-Araújo","doi":"10.1016/j.pedneo.2023.12.015","DOIUrl":"https://doi.org/10.1016/j.pedneo.2023.12.015","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145002032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Type II reversible splenial lesion syndrome in a 6-year-old boy similar to adrenoleukodystrophy on imaging: A case report.","authors":"Baoyun Liang, Jing Liu, Lian Gu","doi":"10.1016/j.pedneo.2025.05.009","DOIUrl":"https://doi.org/10.1016/j.pedneo.2025.05.009","url":null,"abstract":"","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}