Pediatrics and Neonatology最新文献_第10页

Quality improvement of pediatric colonoscopy by application of bundle and centralization: A single-center review 通过捆绑和集中化应用提高儿科结肠镜检查的质量：单中心回顾

IF 2.1 4区医学

Pediatrics and Neonatology Pub Date : 2024-05-01 DOI: 10.1016/j.pedneo.2023.05.009

Shu-Chao Weng , Hung-Chang Lee , Chun-Yan Yeung , Wai-Tao Chan , Hsuan-Chih Lao , Chuen-Bin Jiang

{"title":"Quality improvement of pediatric colonoscopy by application of bundle and centralization: A single-center review","authors":"Shu-Chao Weng , Hung-Chang Lee , Chun-Yan Yeung , Wai-Tao Chan , Hsuan-Chih Lao , Chuen-Bin Jiang","doi":"10.1016/j.pedneo.2023.05.009","DOIUrl":"10.1016/j.pedneo.2023.05.009","url":null,"abstract":"<div><h3>Background</h3><p>To assess the quality change of our single-center pediatric colonoscopy after applying bundle for bowel preparation and general anesthesia and centralize the procedure using terminal ileum (TI) intubation rate as the main indicator.</p></div><div><h3>Methods</h3><p>All elective colonoscopies performed for patients younger than 18 years old in MacKay Memorial Hospital from July 2015 through June 2020 (assigned to group 1, before bundle) and from August 2020 through July 2021 (assigned to group 2, after bundle) were retrospectively reviewed for demographic characteristics, indications, bowel preparation agent and cleansing level, diagnostic and therapeutic procedures, maximum intestinal level reached, and cecal intubation and total procedure time. Statistical analysis was done using <em>P</em> value < 0.05 considered to be significant.</p></div><div><h3>Results</h3><p>Analysis included 45 and 32 colonoscopies in group 1 and 2, respectively. Bloody stool was the most frequent indication in both groups. Both TI intubation rate (42.2 % vs. 75.0 %, <em>P</em> = 0.004) and biopsy rate (45.0 % vs. 75.9 %, <em>P</em> = 0.01) increased significantly from group 1 to group 2. The narrower standard deviation of bowel preparation score <strong>(</strong>1.93 vs. 1.15) and total procedure time (37.71 vs. 22.29) in group 2 indicated a more stable quality, although the mean showed no difference. There was no statistical difference in age, gender, body weight, cecal intubation rate, or cecal intubation time.</p></div><div><h3>Conclusion</h3><p>A higher TI intubation rate and biopsy rate indicated an improved quality of pediatric colonoscopy after applying bundle including bowel preparation and general anesthesia, with additional centralization.</p></div>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1875957223001754/pdfft?md5=a1207a20552cfc353e8625f542b0b56a&pid=1-s2.0-S1875957223001754-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136009918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Encephalocele as a rare complication of conservatively managed cranial aplasia cutis in a boy with Adams–Oliver syndrome 一名患有亚当斯-奥利弗综合征的男孩因颅骨切口增生症接受保守治疗后出现的罕见并发症--脑积水。

IF 2.1 4区医学

Pediatrics and Neonatology Pub Date : 2024-05-01 DOI: 10.1016/j.pedneo.2023.10.006

Julia Elrod , Miriam Fattouh , Christian Hagemann , Ingo Königs

引用次数: 0

Serum lactate and lactate clearance as early predictors of mortality in preterm neonates 血清乳酸和乳酸清除率是早产新生儿死亡率的早期预测指标

IF 2.1 4区医学

Pediatrics and Neonatology Pub Date : 2024-05-01 DOI: 10.1016/j.pedneo.2023.10.004

Vinay Kulkarni , Shiv Sajan Saini , Venkataseshan Sundaram , Kanya Mukhopadhay , Sourabh Dutta , Praveen Kumar

引用次数: 0

Association between sleeping position and cardiac output compromise in neonates: Current evidence and future research 新生儿睡眠姿势与心输出量受损之间的关系：当前证据与未来研究。

IF 2.1 4区医学

Pediatrics and Neonatology Pub Date : 2024-05-01 DOI: 10.1016/j.pedneo.2024.04.002

Kai-Hsiang Hsu, Ming-Chou Chiang

引用次数: 0

Corrigendum to “Peritoneal lymphomatosis presented with acute intermittent abdominal pain in a child” [Pediatr Neonatol 64 (3) (2023) 362–363] 腹膜淋巴瘤病在一名儿童中表现为急性间歇性腹痛》[Pediatr Neonatol 64 (3) (2023) 362-363]的更正。

IF 2.1 4区医学

Pediatrics and Neonatology Pub Date : 2024-05-01 DOI: 10.1016/j.pedneo.2024.04.001

Pei-Chun Lin , Shu-Huey Chen , Chin-Hung Wei , Shu-Sing Kong , Shih-Yen Chen

引用次数: 0

Effect of sleeping position on cardiac output, pulmonary pressure, and superior vena cava flow in healthy term infants 睡眠姿势对健康足月婴儿心输出量、肺动脉压力和上腔静脉流量的影响

IF 2.1 4区医学

Pediatrics and Neonatology Pub Date : 2024-05-01 DOI: 10.1016/j.pedneo.2023.09.003

Muhammed Karabulut , Hasan Sinan Uslu

{"title":"Effect of sleeping position on cardiac output, pulmonary pressure, and superior vena cava flow in healthy term infants","authors":"Muhammed Karabulut , Hasan Sinan Uslu","doi":"10.1016/j.pedneo.2023.09.003","DOIUrl":"10.1016/j.pedneo.2023.09.003","url":null,"abstract":"<div><h3>Background</h3><p>Although the mechanism of action in newborns is unknown, sleep positioning is associated with many pathophysiological events. This study aimed to compare the effects of supine and prone sleeping positions on cardiac output (CO), systolic pulmonary arterial pressure (SPAP), and superior vena cava (SVC) flow in healthy newborns.</p></div><div><h3>Methods</h3><p>In the first 24–72 h of life, 40 healthy term newborns born in the same hospital were included in this prospective, cross-sectional, observational study. CO, SVC flow, and SPAP values of newborns in the supine and prone sleeping positions were calculated using echocardiographic examination. The measurements were statistically compared.</p></div><div><h3>Results</h3><p>In the supine sleeping position, CO, SVC flow, and SPAP were 235.00 (193.07–283.30) ml/kg/min, 92.80 (77.82–121.87) ml/kg/min, and 27.85 (24.70–30.48) mmHg. In the prone sleeping position, CO, SVC flow, and SPAP were measured as 195.35 (166.00–229.40) ml/kg/min, 67.25 (51.82–96.66) ml/kg/min, 31.60 (28.45–37.20) mmHg, respectively. Depending on sleeping position, these variables were significantly different between the groups.</p></div><div><h3>Conclusion</h3><p>SVC flow and CO decreased in the prone sleeping position compared to the supine sleeping position in healthy newborns, whereas SPAP increased. The different hemodynamic effects of sleeping position on the cardiac, pulmonary, and nervous systems should be considered as flow and pressure changes are important in newborns.</p></div>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1875957223001845/pdfft?md5=4567b39cfbcfbcfa79bf92b900eb26a4&pid=1-s2.0-S1875957223001845-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136009278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastric foveolar hyperplasia and gastric outlet obstruction caused by long-term prostaglandin use 长期使用前列腺素导致的胃窝增生和胃出口梗阻

IF 2.1 4区医学

Pediatrics and Neonatology Pub Date : 2024-05-01 DOI: 10.1016/j.pedneo.2024.02.002

Başak Kaya, Hasan Akduman, Dilek Dilli

引用次数: 0

Invasive lactobacillus infection in pediatric patients in a tertiary center in Taiwan – 16 years’ experience and literature review 台湾一家三级医疗中心儿科患者的侵袭性乳酸杆菌感染--16 年的经验和文献综述

IF 2.1 4区医学

Pediatrics and Neonatology Pub Date : 2024-05-01 DOI: 10.1016/j.pedneo.2023.05.013

Wei-Hung Wu , Chien-Chung Lee , Yi-Ching Chen , Ming-Chou Chiang , Cheng-Hsun Chiu

{"title":"Invasive lactobacillus infection in pediatric patients in a tertiary center in Taiwan – 16 years’ experience and literature review","authors":"Wei-Hung Wu , Chien-Chung Lee , Yi-Ching Chen , Ming-Chou Chiang , Cheng-Hsun Chiu","doi":"10.1016/j.pedneo.2023.05.013","DOIUrl":"10.1016/j.pedneo.2023.05.013","url":null,"abstract":"<div><h3>Background</h3><p><em>Lactobacilli</em> are common microorganisms in the human body. Some species were used as probiotics supplement for many purposes such as preventing necrotizing enterocolitis, or improving allergic diseases or diarrhea. Previously, <em>Lactobacillus</em> infection was thought of as contamination due to its low pathogenicity. However, there have been reports of invasive <em>Lactobacillus</em> infection in immunocompromised patients or patients with comorbidities. The purpose of this study was to analyze the clinical characteristics, antibiotic treatment and outcomes of pediatric patients with invasive <em>Lactobacillus</em> infection.</p></div><div><h3>Methods</h3><p>We retrospectively reviewed pediatric patients diagnosed with invasive <em>Lactobacillus</em> infection between 2004 and 2020. Invasive <em>Lactobacillus</em> infection was diagnosed if sterile sites yielded <em>Lactobacillus</em> spp. Clinical manifestations, chronic diseases, potential predisposing factors, medical treatments, antimicrobial susceptibility tests and outcomes were recorded.</p></div><div><h3>Results</h3><p>Fifteen pediatric patients were diagnosed with invasive <em>Lactobacillus</em> infection, accounting for 2.4% of total invasive <em>Lactobacillus</em> infections during the 16-year period. Eleven infections were bacteremia, two were intra-abdominal infections, and two were biliary tract infections. Fever was the most common symptom. Potential predisposing factors were immunocompromised status, central venous device, prolonged antibiotics use and receiving supplemented probiotics for at least one week. All patients survived with favorable outcomes. Most pathogens were identified as <em>Lactobacillus</em> spp<em>,</em> and two were <em>Lactobacillus rhamnosus</em>, which were related to supplemented probiotics. The antimicrobial susceptibility tests showed that <em>Lactobacilli</em> were all sensitive to ampicillin but resistant to glycopeptides.</p></div><div><h3>Conclusion</h3><p>Invasive <em>Lactobacillus</em> infections in pediatric patients were rare. Despite its low pathogenicity, <em>Lactobacillus</em> could cause invasive infection in those immunocompromised patients.</p></div>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S187595722300205X/pdfft?md5=db1fa5baa922f34385d70a3dd1518bc2&pid=1-s2.0-S187595722300205X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135410647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Specialty follow -up care after hospital discharge of patients with multisystem inflammatory syndrome in children associated with COVID-19 from a rural tertiary-care hospital 农村地区护理医院新冠肺炎相关儿童多系统炎症综合征患者出院后的专业随访护理。

IF 2.1 4区医学

Pediatrics and Neonatology Pub Date : 2024-05-01 DOI: 10.1016/j.pedneo.2023.05.011

Inga Aikman , Brandon Wright , Stacey Applegate , Andrea Whitfield , Kamel Alachraf , Sruthipriya Sridhar , Dmitry Tumin , Salma Syed

{"title":"Specialty follow -up care after hospital discharge of patients with multisystem inflammatory syndrome in children associated with COVID-19 from a rural tertiary-care hospital","authors":"Inga Aikman , Brandon Wright , Stacey Applegate , Andrea Whitfield , Kamel Alachraf , Sruthipriya Sridhar , Dmitry Tumin , Salma Syed","doi":"10.1016/j.pedneo.2023.05.011","DOIUrl":"10.1016/j.pedneo.2023.05.011","url":null,"abstract":"<div><h3>Background</h3><p>The clinical features of Multisystem Inflammatory Syndrome in Children (MIS-C) have been well documented, but there is limited data regarding the short term and longitudinal outcomes of children living in rural areas. We report the demographic and clinical features, as well as the multi-specialty follow-up of patients with MIS-C served by a large tertiary care rural health system.</p></div><div><h3>Methods</h3><p>Patients that met the Centers for Disease Control (CDC) case definition of MIS-C admitted between March 1, 2020, and March 31, 2021, were included in this case series. Manual chart review was used to report demographic characteristics, clinical, laboratory and radiologic features during acute hospitalization and multispecialty follow-up, and adherence to follow-up 6–10 weeks after hospital discharge.</p></div><div><h3>Results</h3><p>Twenty-one patients with MIS-C were admitted at our center during the review period. Ninety percent of the cohort required intensive care during hospitalization. Of 19 patients with measured ejection fractions, 52 % had some degree of left ventricular dysfunction on admission; nine patients had electrocardiogram changes on admission. The majority of patients had elevated inflammatory markers during hospitalization. Most patients had resolution of symptoms, improvement in inflammatory markers, and normal cardiac function at the time of discharge. Follow-up with pediatric cardiology, hematology-oncology and infectious disease was indicated for most patients at discharge. Of these, 100 % of patients kept initial follow-up appointments with pediatric cardiology and infectious disease, while 94 % kept initial follow-up appointments with pediatric hematology-oncology.</p></div><div><h3>Conclusion</h3><p>Though most patients were critically ill during hospitalization, the majority had resolution of cardiac abnormalities and inflammatory markers at discharge and timely follow-up with multiple subspecialists after admission with MIS-C.</p></div>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1875957223001778/pdfft?md5=a8234e7af5ed0cf08d8f05640726c3bd&pid=1-s2.0-S1875957223001778-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postnatal longitudinal analysis of serum nitric oxide and eosinophil counts in extremely preterm infants 极早产儿血清一氧化氮和嗜酸性粒细胞计数的产后纵向分析

IF 2.1 4区医学

Pediatrics and Neonatology Pub Date : 2024-05-01 DOI: 10.1016/j.pedneo.2023.08.006

Hirokazu Watanabe , Yosuke Washio , Kei Tamai , Daisaku Morimoto , Tomoka Okamura , Junko Yoshimoto , Hidehiko Nakanishi , Misao Kageyama , Atsushi Uchiyama , Hirokazu Tsukahara , Satoshi Kusuda

{"title":"Postnatal longitudinal analysis of serum nitric oxide and eosinophil counts in extremely preterm infants","authors":"Hirokazu Watanabe , Yosuke Washio , Kei Tamai , Daisaku Morimoto , Tomoka Okamura , Junko Yoshimoto , Hidehiko Nakanishi , Misao Kageyama , Atsushi Uchiyama , Hirokazu Tsukahara , Satoshi Kusuda","doi":"10.1016/j.pedneo.2023.08.006","DOIUrl":"10.1016/j.pedneo.2023.08.006","url":null,"abstract":"<div><h3>Background</h3><p>Nitric oxide (NO) may be related to the pathogenesis of several morbidities in extremely preterm infants, including late-onset adrenal insufficiency. However, eosinophilia is observed under pathological conditions with adrenal insufficiency. Therefore, this study explored postnatal changes in NO levels and eosinophil counts in extremely preterm infants with and without morbidities.</p></div><div><h3>Methods</h3><p>Nineteen extremely preterm infants with a median gestational age of 27.0 weeks and median birth weight of 888 g were enrolled in this study. Serum levels of nitrogen oxides (NOx) and peripheral blood eosinophil counts were measured at birth and every 2 weeks thereafter. Morbidities of the study group were diagnosed using a single criterion.</p></div><div><h3>Results</h3><p>Serum NOx levels (mean ± standard deviation) were 22.5 ± 14.9 μmol/L, 51.2 ± 23.7 μmol/L, 42.4 ± 15.2 μmol/L, and 33.8 ± 9.4 μmol/L at birth and 2, 4, and 6 weeks of age, respectively. The serum NOx level at 2 weeks of age was significantly higher than that at birth and 6 weeks of age. Eosinophil counts, which increase with adrenal insufficiency, were measured simultaneously and were 145 ± 199/μL, 613 ± 625/μL, 466 ± 375/μL, and 292 ± 228/μL at birth and 2, 4, and 6 weeks of age, respectively. These values showed that the eosinophil count was significantly higher at 2 weeks of age than at birth and 6 weeks of age. The serum NOx level of infants without chorioamnionitis was significantly increased at 4 weeks of age, and the eosinophil count of infants with necrotizing enterocolitis was significantly increased at 2 weeks of age. No correlation with the NOx level or eosinophil count was observed in infants with late-onset circulatory collapse.</p></div><div><h3>Conclusion</h3><p>The postnatal serum NOx level and eosinophil count were significantly correlated with each other and peaked at 2 weeks of age.</p></div>","PeriodicalId":56095,"journal":{"name":"Pediatrics and Neonatology","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1875957223001730/pdfft?md5=032a37dda9de15f68857bc57c98501b4&pid=1-s2.0-S1875957223001730-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136009778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0