Science Progress最新文献

{"title":"Evaluation of aging impact on rheological and chemical characteristics of crumb rubber-modified warm asphalt binders.","authors":"Alaa Sukkari, Ghazi Al-Khateeb, Waleed Zeiada, Helal Ezzat","doi":"10.1177/00368504241300198","DOIUrl":"10.1177/00368504241300198","url":null,"abstract":"<p><p>Asphalt pavements are consistently subjected to environmental and loading conditions that affect their durability, such as oxidative aging. Modification of the pavements assists in reducing the aging-induced stiffness. One of these solutions is crumb rubber (CR)-modified warm mix asphalt (WMA) binders. This study aims to assess the long-term performance and effects of aging on CR-modified WMA binders through a series of physical, rheological, and chemical tests. 2% and 4% of Sasobit, a wax-based additive, and 1.5% and 3% of Zycotherm, a nano-based chemical additive, with 10%, 15%, and 20% CR, were utilized. The binders were aged using a rolling thin film oven (RTFO) and pressurized aging vessel. The unaged and long-term aged asphalt binders were tested. Rheological properties, using master curves and zero shear viscosity, physical properties measured through elastic recovery, along with chemical analysis using Fourier transform infrared (FTIR) spectroscopy, were carried out on the binders before and after aging. Based on the physical and rheological aging indices, Sasobit-modified asphalt binders exhibited superior resistance to aging and rutting compared to Zycotherm-modified binders. Specifically, the Sasobit 4% and 20% crumb rubber blend showed the highest resistance to physical aging, while Zycotherm-modified binders demonstrated improved chemical aging resistance. Adding crumb rubber significantly enhanced the stiffness and elasticity of the asphalt binders, further reducing the effects of aging. FTIR analysis confirmed that Sasobit and crumb rubber reduced oxidation and volatile component loss during aging.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241300198"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11590138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of periodic vibration-isolation piles on soil vibration in deep-buried tunnels of suburban railways.","authors":"Shusen Cao, Dong Li, Jili Yin, Qin Xu, Dongdong Qian, Chao Chen, Hongkai Wang, Lunzheng Zhang, Xiangdong Shi, Futong Wang","doi":"10.1177/00368504241282801","DOIUrl":"10.1177/00368504241282801","url":null,"abstract":"<p><p>This study aims to investigate the impact of isolation piles on soil vibrations in the environment surrounding suburban railways. Initially, a comprehensive numerical model of the train was established to simulate the wheel-rail interaction forces, which were then applied to a three-dimensional coupled track-soil model. The accuracy of the model was validated through comparison with measured data. The focus of the research is to analyze the vibration isolation effects of single-row, double-row, and triple-row piles, with particular attention to the influence of pile spacing in double-row piles on isolation effectiveness. The study found that the effectiveness of isolation piles in reducing soil vibration acceleration within a depth range of 0 m to 2 m decreases as the pile spacing increases. When the pile spacing reaches 2 times the pile radius, single-row piles exhibit the best vibration isolation effect. For reducing peak soil acceleration within a depth range of 4 m to 8 m, single-row piles are most effective when the pile spacing exceeds 1 times the pile radius. To attenuate peak soil acceleration at depths greater than 6 m, the pile spacing for single-row and double-row piles should be set at 0.5 times the pile radius, while triple-row piles should have a spacing of 1 times the pile radius. In terms of reducing peak soil velocity, single-row piles demonstrate better vibration isolation effects. To reduce peak velocity in soil at depths greater than 2 m, the pile spacing for single-row and double-row piles should be set at 0.5 times the pile radius, while triple-row piles should be spaced at 1 times the pile radius. For reducing peak soil displacement, single-row piles should be used, with optimal results achieved at a spacing of 1 times the pile radius.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241282801"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and implementation of a field robot using a parallelogram mechanism.","authors":"Thanh Phuong Nguyen, Hung Nguyen, Thinh Ngo","doi":"10.1177/00368504241291124","DOIUrl":"10.1177/00368504241291124","url":null,"abstract":"<p><p>To meet various industrial requirements such as ease of motion, scalability, and cost efficiency, it is necessary to innovate the design of robotic platforms. In this research, a novel approach, from mechanical design to control implementation, is introduced for launching a robotic platform using a parallelogram mechanism. First, a reverse engineering process is applied, progressing from kinematics to dynamics. Then, several mechanical computations are conducted to ensure the structural stability of the robot framework. Subsequently, the dynamic performance of the system is analyzed, focusing on the driving torque and moments in each link. Additionally, the electrical design and transfer function of each joint are identified to ensure practical execution. To validate the effectiveness and feasibility of the design, both numerical simulations and experimental tests are performed. Theoretical results show the dynamic response of the proposed method, particularly in terms of the driving moments of the robotic joints. In real-world tests, various trajectories, such as different rectangular paths, are demonstrated to showcase the robot's capabilities. From these results, it is clear that the proposed approach is both feasible and applicable in practical scenarios.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241291124"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing the quality and consumer satisfaction of dragon fruit beverage production: The effects of geological origin and processing conditions.","authors":"Thinh Van Pham, Thuy Xuan Cao, Ngoc Thi Hong Le, Ai Minh Pham, Hung Tuan Trinh, Dat Tien Nguyen, Anh Le Tuan Hoang, Minh Quang Bui, Tung Ngoc Nguyen, Minh Ngoc Truong, Tao Minh Hoang","doi":"10.1177/00368504241300854","DOIUrl":"10.1177/00368504241300854","url":null,"abstract":"<p><strong>Objectives: </strong>In this study, the impacts of various processing parameters on the quality and consumer satisfaction of dragon fruit beverages were investigated in order to establish an informative framework for the manufacturing of commercial dragon fruit beverages, focusing on health benefits and safety for consumers, and sensory appeal of the products.</p><p><strong>Methods: </strong>This study employed various analytical methods to quantify some important phytochemical compounds in dragon fruit juice such as total and reducing sugars, vitamin C, betacyanins, anthocyanins, polyphenol, and so forth. This study also employed the Box-Behnken response surface experimental design to optimize various processing parameters for quality and consumer satisfaction, which include enzymatic pectin hydrolysis parameters and formulation for dragon fruit energy drink.</p><p><strong>Results: </strong>The results from this study indicated a causal relationship between geological origin and some important characteristics of dragon fruit juice, emphasizing the need to track the source of fruits to ensure consistent quality of juice products. This study also systematically determined the impacts of various enzymatic hydrolysis, thermal sterilization, and formulation parameters on both nutrition content and sensory aspects of dragon fruit beverages, while also successfully optimized these parameters for the best outcomes.</p><p><strong>Conclusion: </strong>This study had successfully achieved the objective of establishing a valuable framework for the manufacturing of commercial dragon fruit beverages, focusing on health benefits and safety for consumers, and sensory appeal of the products.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241300854"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A secure transaction and smart contract architecture for internet of vehicles.","authors":"Hua-Yi Lin","doi":"10.1177/00368504241296039","DOIUrl":"10.1177/00368504241296039","url":null,"abstract":"<p><p>Recently, with the popularity of Internet of vehicles (IoV), there is an increasing market demand for integrating blockchain technology and smart contracts in electric vehicles. By utilizing distributed blockchain and smart contract technology, it provides data integrity preservation, traceability, and prevention of forgery. These features can be effectively used in the automated charging system. As a result, IoV can utilize blockchain and smart contract technologies to facilitate seamless payment for charging fees, tolls, parking fees, online shopping and other associated expenses without the need for intermediaries. However, since blockchain and smart contracts operate in an open internet environment, there is a risk of tampering with transaction records. Therefore, enhancing security becomes a crucial concern. The main aim of this study is to emphasize the growing significance of securing transactions and smart contracts in an open transmission environment to prevent potential damage or alteration.In order to achieve the implementation of secure smart contracts within a resource-constrained IoV, this study investigates various cryptographic mechanisms and realizes the elliptic curve cryptosystem (ECC) is widely recognized for providing strong security with shorter key lengths compared to other public key cryptography methods. This makes it ideal for environments with limited resources. Furthermore, in order to enhance the performance of smart contracts, this study proposes a cloud server architecture for parallel storage of smart contracts to improve access speed. Additionally, we introduce an automated trading framework for smart contracts that operates without human intervention.Finally, this study uses ECC to ensure the secure transmission of transaction data among the vehicle, base station, and cloud server, as well as to provide mutual verification of identities across all entities involved in the operation. As a result, this study proposes a secure architecture for blockchain and smart contracts that can autonomously initiate transactions while ensuring secure transmission and protection in the IoV.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241296039"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11590135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of walking performance between individuals with and without asymptomatic peripheral artery disease using the six-minute walk test and the incremental shuttle walk test.","authors":"Sothida Nantakool, Busaba Chuatrakoon, Cattaleeya Sittichoke, Supatcha Konghakote, Kittipan Rerkasem, Supawan Buranapin, Sawat Kanlayanee, Natthaset Pothaya, Jitbergbarn Kidarn","doi":"10.1177/00368504241305822","DOIUrl":"10.1177/00368504241305822","url":null,"abstract":"<p><strong>Objective: </strong>Two walking tests including the six-minute walk test (6MWT) and the incremental shuttle walk test (ISWT) are widely used to evaluate functional ability in individuals with disease conditions. However, it remains unclear whether these walking tests effectively manifest clinical impairment in individuals with asymptomatic peripheral artery disease (PAD). We aimed (i) to compare the walking performance of individuals with and without asymptomatic PAD using the 6MWT and ISWT, and (ii) to investigate the correlation between ankle-brachial index and toe-brachial index (ABI-TBI) and the walking distance.</p><p><strong>Methods: </strong>A cross-sectional, crossover, matched pairs design was employed in this study. Asymptomatic PAD was diagnosed using ABI-TBI measurements. Seventy-six participants (38 with asymptomatic PAD and 38 without PAD) were randomly ordered to perform the walking tests. During the 6MWT, participants walked along the 30-meter corridor at their self-selected pace for six minutes, and the six-minute walk distance (6MWD) covered was recorded. In the ISWT, participants walked at a 12 prescribed speed level, and the incremental shuttle walk distance (ISWD) covered was recorded.</p><p><strong>Results: </strong>Result revealed no difference in 6MWD between individuals with asymptomatic PAD and without PAD (mean distance: 501.6 m vs 516.8 m, p = 0.24). Asymptomatic PAD individuals exhibited a significantly shorter ISWD than those without PAD (median distance: 270 m vs 340 m, p = 0.003). No participants reported any leg pain symptoms during the 6MWT and ISWT. A statistically significant positive correlation was observed between the right leg TBI and ISWD in all participants (r = 0.23, p = 0.04).</p><p><strong>Conclusions: </strong>Individuals with asymptomatic PAD demonstrated poorer walking performance than those without PAD when assessed using ISWT but not the 6MWT. Asymptomatic PAD is also associated with diminished walking performance during the ISWT. Thus, ISWT may show the clinical impairment in this population.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241305822"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical and diffusion property and multi-objective optimization of rubber seals exposed to high-pressure hydrogen gas.","authors":"Yi Ma, Xuhang Wu, Xiaoling Deng, Xudong Peng, Xiangkai Meng","doi":"10.1177/00368504241304197","DOIUrl":"10.1177/00368504241304197","url":null,"abstract":"<p><p>As the critical components in hydrogen refueling, storage, and transportation systems, the degradation and failure of rubber O-ring seals under a high-pressure (HP) hydrogen environment (up to 100 MPa) directly affect hydrogen energy safety. Clarifying the interaction mechanism of hydrogen diffusion and the mechanical properties of rubber seals is essential for HP hydrogen infrastructure. A hydrogen diffusion-mechanical sequential numerical model is built to investigate the sealing performance and hydrogen diffusion behaviors of rubber seals using ABAQUS software. The effects of hydrogen swelling environmental pressure (5∼100 MPa) and stress-concentration gradient on mechanical and contact characteristics and hydrogen concentration distribution are analyzed for the rubber seals with/without backup rings, respectively. Furthermore, the orthogonal experimental and comprehensive frequency analysis methods are employed to evaluate the significance of the main structural and assembly parameters and obtain the optimal schemes of the rubber seals under the HP environment. The results show that the stress concentration and rubber extrusion easily occur at the sealing clearance of the O-rings with swelling after pre-compression and pressurization. The hydrogen diffusion of the O-ring is mainly driven by the concentration difference and stress gradient, with the former being the dominant factor. With the increase in the hydrogen pressure, the effective sealing rate along the sealing surface decreases sharply, and the non-uniformity of hydrogen concentration and the possibility of fatigue damage in the rubber O-rings increase. Two multi-objective optimization schemes (Ⅰ and Ⅱ) for the main structural and assembly parameters of rubber seals are obtained by intuitive analysis and comprehensive frequency analysis to improve the extrusion tendency and sealing reliability of rubber seals in the HP hydrogen environment.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241304197"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on surface roughness of high-speed milling 7075-T6 aluminum alloy using nanofluid/ultrasonic atomization minimal quantity lubrication system.","authors":"Wen-Hsien Ho, Jinn-Tsong Tsai, Wei-Tai Huang","doi":"10.1177/00368504241284823","DOIUrl":"10.1177/00368504241284823","url":null,"abstract":"<p><p>This study employed a self-developed nanofluid/ultrasonic atomization minimal quantity lubrication system. The use of ultrasonic cavitation can effectively improve the accumulation of nanofluids via van der Waals force bonding and enhance their efficiency. This system is a high-speed milling manufacturing innovation in lubrication technology. Two types of nanoparticles (multiwalled carbon nanotubes and MoS₂ nanoparticles) were used to facilitate the mixing of nanofluids and their lubrication in the high-speed milling of 7075-T6 aluminum alloy. The surface roughness of each group of experimental results was used as the characteristic index. The surface roughness obtained from the optimization of the experimental results was 0.51 μm, while the worst group, which was based on the original orthogonal table, had a surface roughness of 1.05 μm, demonstrating an improvement of 51.43% in the quality characteristics. Results of comparative experiments demonstrated that using a nanofluid mixed with multiwalled carbon nanotubes and MoS₂ nanoparticles exerted better effects on surface roughness, tool wear, and workpiece burrs than using only nanofluids with single nanoparticles. This finding can be attributed to the mixed nanofluid, which simultaneously possesses the good grinding capability of MoS₂ and the excellent heat transfer property of multiwalled carbon nanotubes.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241284823"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"YOLO-Faster: An efficient remote sensing object detection method based on AMFFN.","authors":"Yicheng Tong, Guan Yue, Longfei Fan, Guosen Lyu, Deya Zhu, Yan Liu, Boyuan Meng, Shu Liu, Xiaokai Mu, Congling Tian","doi":"10.1177/00368504241280765","DOIUrl":"10.1177/00368504241280765","url":null,"abstract":"<p><p>As a pivotal task within computer vision, object detection finds application across a diverse spectrum of industrial scenarios. The advent of deep learning technologies has significantly elevated the accuracy of object detectors designed for general-purpose applications. Nevertheless, in contrast to conventional terrestrial environments, remote sensing object detection scenarios pose formidable challenges, including intricate and diverse backgrounds, fluctuating object scales, and pronounced interference from background noise, rendering remote sensing object detection an enduringly demanding task. In addition, despite the superior detection performance of deep learning-based object detection networks compared to traditional counterparts, their substantial parameter and computational demands curtail their feasibility for deployment on mobile devices equipped with low-power processors. In response to the aforementioned challenges, this paper introduces an enhanced lightweight remote sensing object detection network, denoted as YOLO-Faster, built upon the foundation of YOLOv5. Firstly, the lightweight design and inference speed of the object detection network is augmented by incorporating the lightweight network as the foundational network within YOLOv5, satisfying the demand for real-time detection on mobile devices. Moreover, to tackle the issue of detecting objects of different scales in large and complex backgrounds, an adaptive multiscale feature fusion network is introduced, which dynamically adjusts the large receptive field to capture dependencies among objects of different scales, enabling better modeling of object detection scenarios in remote sensing scenes. At last, the robustness of the object detection network under background noise is enhanced through incorporating a decoupled detection head that separates the classification and regression processes of the detection network. The results obtained from the public remote sensing object detection dataset DOTA show that the proposed method has a mean average precision of 71.4% and a detection speed of 38 frames per second.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241280765"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements of metallic nanoparticles: A promising frontier in cancer treatment.","authors":"Ali Al-Samydai, Maha N Abu Hajleh, Farah Al-Sahlawi, Hamdi Nsairat, Arwa Al Khatib, Moath Alqaraleh, Alia K Ibrahim","doi":"10.1177/00368504241274967","DOIUrl":"10.1177/00368504241274967","url":null,"abstract":"<p><p>The incidence of cancer is increasing and evolving as a major source of mortality. Nanotechnology has garnered considerable scientific interest in recent decades and can offer a promising solution to the challenges encountered with traditional chemotherapy. Nanoparticle utilization holds promise in combating cancer and other diseases, offering exciting prospects for drug delivery systems and medicinal applications. Metallic nanoparticles exhibit remarkable physical and chemical properties, such as their minute size, chemical composition, structure, and extensive surface area, rendering them versatile and cost-effective. Research has demonstrated their significant and beneficial impact on cancer treatment, characterized by enhanced targeting abilities, gene activity suppression, and improved drug delivery efficiency. By incorporating targeting ligands, functionalized metal nanoparticles ensure precise energy deposition within tumors, thereby augmenting treatment accuracy. Moreover, beyond their therapeutic efficacy, metal nanoparticles serve as valuable tools for cancer cell visualization, contributing to diagnostic techniques. Utilizing metal nanoparticles in therapeutic systems allows for simultaneous cancer diagnosis and treatment, while also facilitating controlled drug release, thus revolutionizing cancer care. This narrative review investigates the advancements of metal nanoparticles in cancer treatment, types and mechanisms in targeting cancer cells, application in clinical scenarios, and potential toxicity in medicine.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241274967"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11459474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}