Science Progress最新文献

{"title":"Advance in the pathogenesis of otitis media with effusion induced by platelet-activating factor.","authors":"Wei Liu, Lin Shi, Ya Feng","doi":"10.1177/00368504241265171","DOIUrl":"10.1177/00368504241265171","url":null,"abstract":"<p><p>A non-suppurative inflammatory disease of the middle ear with middle ear effusion and conductive hearing loss is called otitis media with effusion. Poor eustachian tube function, immunological factors, viral factors, and other factors are primarily involved in its pathophysiology, which has not yet been completely understood. Several researcher scholars have recently studied platelet-activating factor and they found that platelet-activating factor is closely associated to the occurrence, development, and outcome of otitis media with effusion. Platelet-activating factor is a significant element contributing to the extension of otitis media with effusion. In order to give a reference for further investigation into the mechanism and clinical management of this illness, the research status of platelet-activating factor and otitis media with effusion during the past two decades is reviewed in this study, along with the mechanisms of otitis media with effusion leading to otitis media with effusion.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241265171"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dengue outbreak 2023 in Bangladesh: From a local concern to a global public health issue.","authors":"Sumaiya Binte Reza, Md Masuk-Ur-Rahman Shoukhin, Sakif Ahamed Khan, Syed Masudur Rahman Dewan","doi":"10.1177/00368504241289462","DOIUrl":"10.1177/00368504241289462","url":null,"abstract":"<p><p>Dengue, a viral infection transmitted by mosquitoes, has become a substantial public health issue in Bangladesh. The high population density and subtropical-tropical climate of the nation create conducive environments for the transmission of the virus. The recent increase in dengue cases in Bangladesh prompts an inquiry into the potential for the virus to progress into an epidemic manifestation. Bangladesh is prone to dengue outbreaks due to a multitude of contributing factors. To commence, the virus is endemic to tropical and subtropical regions, and climate change is contributing to the expansion of its range. Additionally, the high population density in Bangladesh amplifies the vulnerability to dengue transmission. Intimate human proximity elevates the probability of contracting mosquito stings and transmitting viruses. The escalating incidence of dengue in Bangladesh is substantiated by the growing count of documented cases. The emergence of severe dengue is a contributing aspect that raises concerns about the potential worldwide consequences of the disease. It could potentially head from Bangladesh to neighboring nations via an infected individual. There exist apprehensions due to the substantial employment of Bangladeshi laborers overseas, compounded by the presence of foreign laborers within Bangladesh. The endeavor to control dengue in Bangladesh continues to face ongoing challenges. This review addresses the complexities of dengue transmission, assesses Bangladesh's readiness for managing epidemics, analyzes risk factors associated with dengue, and suggests preventive measures to mitigate the possibility of worldwide consequences of dengue originating within the nation.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241289462"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142373630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital economy and green transformation of regional industries: New insights from sustainability.","authors":"Xiaoxing Wang, Jiqiang Huang, Kengcheng Zheng, Baoliu Liu","doi":"10.1177/00368504241291351","DOIUrl":"10.1177/00368504241291351","url":null,"abstract":"<p><p>Studying the impact of the digital economy on carbon emissions in the distribution industry is of great significance for realizing sustainable development goals and coping with climate change. This study finds that increasing the level of digital economy development can reduce the carbon emission intensity of the circulation industry through fixed-effects modeling. Moreover, the effect is different in different geographic regions, and the improvement of the digital economy development level in the east and central regions can significantly reduce the carbon emission intensity of the distribution industry. The digital economy can simultaneously reduce the carbon emission intensity of the circulation industry by reducing the degree of labor factor mismatch in the circulation industry and improving the regional green innovation capacity. Therefore, in order to promote the green development of the distribution industry, it is also necessary to make efforts to improve the construction of network infrastructure, accelerate the process of research and development and cultivation of green technology, and break down the barriers of cross-regional mobility of talents.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241291351"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11504114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of three evolutionary algorithms for group scheduling in theme parks with multitype facilities.","authors":"Yi-Chih Hsieh, Peng-Sheng You","doi":"10.1177/00368504241278424","DOIUrl":"https://doi.org/10.1177/00368504241278424","url":null,"abstract":"<p><p>During the peak tourist season, large theme parks often experience a simultaneous influx of visitors, resulting in prolonged waiting times for popular attractions. This extended waiting significantly reduces tourists' satisfaction and may negatively impact their willingness to revisit the theme park. In Taiwan, schools at all levels often plan graduation trips to theme parks for their students. Students are divided into groups and must enter and exit the theme park at the same time. This article presents a new theme park problem with multitype facilities (TPP-MTF) for student groups. Based on the group's preference for theme park facilities, multitype reserved tickets with popular facilities are designed for groups, so groups do not need to wait for the reserved facilities. Since the waiting time for groups can be reduced, the theme park can also obtain ticket fees in advance and estimate the number of visitors to the theme park, so the theme park and the group can achieve a win-win situation. This article proposes a new decoding approach for a random permutation of integer sequence and embeds it into an immune-based algorithm, genetic algorithm, and particle swarm optimization algorithm to solve the TPP-MTF problem. A theme park in Taiwan was taken as an example and numerical results of the three algorithms were analyzed and compared to verify the effectiveness of the proposed algorithms.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241278424"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11483685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How green governance empowers high-quality development: An EKC framework-based analysis of ESG and green total factor productivity.","authors":"Zhe You, Dandan Chen, Chuandi Fang, Mengjie Gao, Jinhua Cheng","doi":"10.1177/00368504241288782","DOIUrl":"https://doi.org/10.1177/00368504241288782","url":null,"abstract":"<p><p>High-quality development represents a fundamental shift in China's economy from scale and speed to quality and efficiency. In this transition, environmental, social, and governance (ESG) practices are not only closely integrated with China's development strategy but have also become a core standard for measuring development quality. Nevertheless, research on how ESG practices specifically promote high-quality development in Chinese enterprises remains limited. Based on the environmental Kuznets curve (EKC) theory framework, this study uses data from the Huazheng ESG Index from 2009 to 2022 and employs fixed effect models, mediation effect models, and heterogeneity analysis to examine the specific impact of China's ESG practices on corporate high-quality development from multiple dimensions. The results show that there is a \"U-shaped\" relationship between the ESG practices of Chinese listed companies and green total factor productivity (GTFP). Initially, improving ESG practices may temporarily suppress GTFP, but as ESG levels further improve, they exhibit a significant positive impact on GTFP. Corporations significantly boost productivity by alleviating financing constraints and promoting green technological innovation, although the direct impact on technological advancement remains relatively limited. In China's western regions and industries such as manufacturing, electricity, heat, gas, and water production and supply, wholesale and retail, and information transmission, software, and information technology services, the positive effects of ESG on GTFP are particularly evident. Based on these findings, it is recommended that governments and financial institutions collaborate to promote green credit policies and increase support for the research and development of green technologies. Additionally, environmental education and resource use optimization should be strengthened, especially in industries such as agriculture, forestry, animal husbandry, and fisheries, and the exchange of ESG technologies and experiences between industries should be encouraged.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241288782"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11489975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Text-image multimodal fusion model for enhanced fake news detection.","authors":"Szu-Yin Lin, Yen-Chiu Chen, Yu-Han Chang, Shih-Hsin Lo, Kuo-Ming Chao","doi":"10.1177/00368504241292685","DOIUrl":"https://doi.org/10.1177/00368504241292685","url":null,"abstract":"<p><p>In the era of rapid internet expansion and technological progress, discerning real from fake news poses a growing challenge, exposing users to potential misinformation. The existing literature primarily focuses on analyzing individual features in fake news, overlooking multimodal feature fusion recognition. Compared to single-modal approaches, multimodal fusion allows for a more comprehensive and enriched capture of information from different data modalities (such as text and images), thereby improving the performance and effectiveness of the model. This study proposes a model using multimodal fusion to identify fake news, aiming to curb misinformation. The framework integrates textual and visual information, using early fusion, joint fusion and late fusion strategies to combine them. The proposed framework processes textual and visual information through data cleaning and feature extraction before classification. Fake news classification is accomplished through a model, achieving accuracy of 85% and 90% in the Gossipcop and Fakeddit datasets, with F1-scores of 90% and 88%, showcasing its performance. The study presents outcomes across different training periods, demonstrating the effectiveness of multimodal fusion in combining text and image recognition for combating fake news. This research contributes significantly to addressing the critical issue of misinformation, emphasizing a comprehensive approach for detection accuracy enhancement.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241292685"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11500224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review of the influence mechanisms of climate-induced events on groundwater microplastic contamination: A focus on aquifer vulnerabilities and mitigation strategies.","authors":"Naing Aung Khant, Regina Martha Lumongsod, Sim Namkoong, Heejung Kim","doi":"10.1177/00368504241306270","DOIUrl":"10.1177/00368504241306270","url":null,"abstract":"<p><p>Climate change and plastic pollution are two main issues that our world is currently facing, and they are mainly linked through various processes, mechanisms, and chemical blueprint. Emerging issues related to microplastic (MP) contamination in freshwater are expanding and diverse research is being carried out globally. Factors causing climate change are increasing the frequency of extreme weather phenomena such as floods, drought, sea level rise, and heat waves, which can directly or indirectly influence the plastic/MP contamination in various ecosystems including groundwater environments. Here, we review the impacts of extreme weather events on MP contamination in freshwater with a specific focus on groundwater environments. This narrative review shows that flooding can have the most adverse effect on the MP pollution in groundwater environments through recharge events. Drought can also have major effects on MP pollution. Karst, alluvial, and coastal aquifers exhibit the highest levels of MP contamination among various aquifer types. Climate change's impact on different types of aquifers can vary depending on hydrogeological conditions and other factors in the groundwater environment. Prevention and comprehensive solutions are crucial for addressing MPs in the environment, with downstream measures being supplementary to upstream ones.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241306270"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11635876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting and evaluating settlement of shallow foundation using machine learning approach.","authors":"Thi Thanh Huong Ngo, Van Quan Tran","doi":"10.1177/00368504241302972","DOIUrl":"10.1177/00368504241302972","url":null,"abstract":"<p><p>This study presents a novel approach to accurately predict the settlement of shallow foundations using advanced machine learning techniques while assessing the influence of key variables. Four machine learning models Gradient Boosting (GB), Random Forest (RF), Support Vector Machine (SVM), and K-Nearest Neighbor (KNN) are enhanced with Particle Swarm Optimization (PSO) for hyperparameter tuning, resulting in hybrid models GB-PSO, RF-PSO, SVM-PSO, and KNN-PSO. The experimental dataset comprises 189 samples, and model performance is rigorously evaluated through K-Fold Cross-Validation alongside R², RMSE, MAE, and MAPE metrics. The results indicate that PSO tuning does not consistently improve the prediction accuracy, with the original models, particularly GB and RF, outperforming their PSO-optimized counterparts. Sensitivity analysis via Shapley Additive Explanation (SHAP) highlights average Standard Penetration Test blow count (SPT) and footing width (B) as the most influential variables, with footing embedment ratio (D_f/B) and net applied pressure (q) also significantly impacting settlement predictions. The study offers a new Excel tool based on the GB model, facilitating practical applications for civil engineers, and providing a dependable, user-friendly tool to predict shallow foundation settlement.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241302972"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From trauma to chronicity: Understanding the incidence and early immune changes of chronic complications in polytrauma patients.","authors":"Cong Zhang, Deng Chen, Qian Wan, Gang Yin, Yang Liu, Jialiu Luo, Shunyao Chen, Zhiqiang Lin, Shuaipeng Gu, Hui Li, Teding Chang, Liming Dong, Peidong Zhang, Zhaohui Tang","doi":"10.1177/00368504241305901","DOIUrl":"10.1177/00368504241305901","url":null,"abstract":"<p><strong>Objective: </strong>Polytrauma is a complex condition associated with poor outcomes and high mortality rates resulting from severe damage and complicated complications. This study sought to ascertain the incidence of chronic complications in polytrauma patients, as well as the early immune changes and risk factors.</p><p><strong>Methods: </strong>A multicenter, prospective and observational cohort study was conducted at the emergency surgery or traumatic intensive care unit (TICU) of the Advanced Trauma Center from August 2020 to July 2023. A total of 2033 consecutive trauma patients were included in the study. In the first 1, 7, and 14 days after admission, flow cytometry and immunoassay kits were used to examine cytokine release and lymphocyte count.</p><p><strong>Results: </strong>Trauma patients were reported 33.8% (687/2033) chronic complication rates, with monotrauma patients reported 8.1% (55/683) and polytrauma patients reported 59.4% (802/1350). And the four most frequent chronic complications in polytrauma patients were chronic musculoskeletal pain (30.4%), post-traumatic osteoarthritis (27.2%), chronic wound (21.6%), and chronic lung injury (14.1.%) .There were significant differences in lymphocyte ratios and cytokine levels, at 1, 7, and 14 day of admission between chronic complication groups (CCP) and not chronic complication groups (N-CCP) in polytrauma. Polytrauma patients with characteristics of higher ratio of Ts_7d ratio (95% CI: 2.01-6.21), Treg_14d (95% CI: 1.12-5.43) and level of IL-6_7d (95% CI: 1.22-4.43), TNF-α_7d (95% CI: 1.05-3.83), IL-10_14d (95% CI: 2.01-6.84) were found to have a higher likelihood of experiencing a chronic complication. Conversely, a higher ratio of Tc_1d (95% CI: 0.53-0.86), Th_1d (95% CI: 0.64-0.95) and Th/Ts_14d (95% CI: 0.21-0.64) were identified as independent protective factors against a chronic complication event.</p><p><strong>Conclusion: </strong>Polytrauma patients exhibit a notable prevalence of chronic complications. Some immune and inflammatory indicators can be observed early in combination after injury to predict the risk of chronic complications after polytrauma.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241305901"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benzodiazepine use and incident risk of sudden cardiac arrest in patients with cardiovascular diseases.","authors":"Chunbao Mo, Shuang Wang, Xia Li, Furong Li, Cheng Jin, Bo Bai, Haolong Pei, Jing Zheng, Fengchao Liang","doi":"10.1177/00368504241295325","DOIUrl":"10.1177/00368504241295325","url":null,"abstract":"<p><strong>Background: </strong>Benzodiazepines (BZDs) are commonly prescribed as adjunctive drugs for patients with cardiovascular diseases (CVDs), particularly those who experience anxiety or insomnia. However, the relationship between the use of BZDs and incident risk of sudden cardiac arrest (SCA) has not been well investigated. In this study, we aimed to examine the association between the use of BZDs and the incident risk of SCA among patients with CVD.</p><p><strong>Method: </strong>In this retrospective cohort study, a total of 74,715 eligible patients with new-onset CVD as a primary cause of hospitalization between July 2016 and August 2022 were included from the health information platform in Shenzhen, China. Among them, 61,761 BZD non-initiators were identified and matched to 12,954 BZD initiators by propensity score at a maximum ratio of 5:1. Propensity score-matched Cox proportional hazard models were used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Over a 12-month follow-up period, 29 (2.24 per 1000 person-years) and 137 (2.22 per 1000 person-years) SCA cases occurred among propensity score-matched BZD initiators and non-initiators, respectively. Patients who initiated BZD treatment were associated with a 101% increased risk of SCA incidence compared with patients without BZD treatment (adjusted HR: 2.01, 95% CI: 1.42, 2.83). Furthermore, compared with the non-use (0 defined daily dose, DDD), the adjusted HR was 1.43 (95% CI: 1.32, 1.56) for the BZD consumption of ≤1 DDD and 2.58 (95% CI: 2.37, 2.81) for the BZD consumption of >1 DDD (<i>P</i> for trend < 0.001) within a 12-month follow-up period.</p><p><strong>Conclusion: </strong>This study provides evidence that BZD initiation may be associated with an increased incident risk of SCA in patients with CVD. Our finding highlights the importance of cautious prescribing BZDs in the health management of patients with CVD.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"107 4","pages":"368504241295325"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}