Dio Andriamanjay , Pierre Castel , Claude D’Ercole , Florence Bretelle , Aubert Agostini , Julie Berbis , Julie Blanc
{"title":"Développement d’un outil d’évaluation de l’anxiété de performance en obstétrique","authors":"Dio Andriamanjay , Pierre Castel , Claude D’Ercole , Florence Bretelle , Aubert Agostini , Julie Berbis , Julie Blanc","doi":"10.1016/j.gofs.2024.01.007","DOIUrl":"10.1016/j.gofs.2024.01.007","url":null,"abstract":"<div><h3>Objective</h3><p>Developing a measuring tool for physician's performance anxiety during obstetrical procedures, as a self-administered questionnaire.</p></div><div><h3>Methods</h3><p>We used the Delphi method. First, we did a literature review to identify the items to submit for the first round. A panel of experts was asked to rate the relevance of items from one to six. For the first round of Delphi, items were retained if more than 70% of respondents assigned a five or six rating. Items were excluded if more than 70% of respondents assigned a one or two rating. All the other items, plus those suggested by the panel, were submitted to a second round of Delphi. The same item selection conditions were applied to the second round.</p></div><div><h3>Results</h3><p>The overall response rate to the Delphi was 79% (19 respondents). At the end of the first round, 14 items were consensually relevant, no item was consensually irrelevant. For the second round, the 18 items that did not find consensus and seven new items suggested by the experts in the first round were submitted. At the end of the second round, nine items were retained by consensus as relevant.</p></div><div><h3>Conclusion</h3><p>This study defined by consensus 23 items for a self-questionnaire to measure specific performance anxiety in obstetrics divided into five dimensions: perceived stress, assessment of the risk of complications, medico-legal risk, impact of the healthcare team and peers, self-confidence and decision-making confidence. We intend to validate this tool in real population.</p></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 6","pages":"Pages 384-390"},"PeriodicalIF":0.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468718924000114/pdfft?md5=898766396e723d182e3fff741c0c498a&pid=1-s2.0-S2468718924000114-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oxytocine et neuroprotection en période néonatale : évidences conceptuelles et précliniques","authors":"Olivier Baud , Marit Knoop","doi":"10.1016/j.gofs.2023.12.005","DOIUrl":"10.1016/j.gofs.2023.12.005","url":null,"abstract":"<div><h3>Objectif</h3><p>La prématurité et le retard de croissance utérin sont responsables de lésions cérébrales associées à l’apparition de troubles neurocognitifs et comportementaux chez plus de 9 millions d’enfants chaque année. Le bénéfice clinique de la plupart des stratégies pharmacologiques visant à prévenir les lésions cérébrales périnatales reste à confirmer. En revanche, l’enrichissement de l’environnement du nouveau-né induit des effets positifs sur la structure et la fonction du cerveau, influence les réponses hormonales du nouveau-né et semble avoir des conséquences neurocomportementales durables pendant la petite enfance et à l’âge adulte. L’ocytocine (OT), un neuropeptide libéré par l’hypothalamus, pourrait représenter la base hormonale de ces effets à long terme.</p></div><div><h3>Méthode</h3><p>Cette revue de la littérature fait le point sur les connaissances concernant l’effet de l’OT chez le nouveau-né et les données précliniques suggérant son effet neuroprotecteur.</p></div><div><h3>Résultats</h3><p>L’OT joue un rôle pendant la période périnatale, dans l’attachement parents-enfant et dans le comportement social. En outre, des études précliniques suggèrent fortement que l’OT endogène et synthétique est capable de réguler la réponse inflammatoire du système nerveux central en réponse aux situations de prématurité ou plus généralement d’agressions du cerveau en développement. L’effet à long terme de l’adminsitration d’OT synthétique au cours du travail est également abordé.</p></div><div><h3>Conclusion</h3><p>L’ensemble des données conceptuelles et expérimentales converge pour indiquer que l’OT serait un acteur clé dans la neuroprotection néonatale, notamment par la régulation de la neuroinflammation.</p></div><div><h3>Objective</h3><p>Prematurity and intra-uterine growth retardation are responsible for brain damage associated with various neurocognitive and behavioral disorders in more than 9 million children each year. Most pharmacological strategies aimed at preventing perinatal brain injury have not demonstrated substantial clinical benefits so far. In contrast, enrichment of the newborn's environment appears to have positive effects on brain structure and function, influences newborn hormonal responses, and has lasting neurobehavioral consequences during infancy and adulthood. Oxytocin (OT), a neuropeptide released by the hypothalamus, may represent the hormonal basis for these long-term effects.</p></div><div><h3>Method</h3><p>This review of the literature summarizes the knowledge concerning the effect of OT in the newborn and the preclinical data supporting its neuroprotective effect.</p></div><div><h3>Results</h3><p>OT plays a role during the perinatal period, in parent-child attachment and in social behavior. Furthermore, preclinical studies strongly suggest that endogenous and synthetic OT is capable of regulating the inflammatory response of the central nervous system in response to situations of prematurity or more g","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 6","pages":"Pages 418-424"},"PeriodicalIF":0.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S246871892300257X/pdfft?md5=30ced80001e5d926c8aa3d21fea46062&pid=1-s2.0-S246871892300257X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139038182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"L’accouchement des femmes enceintes de jumeaux : les enseignements de l’étude nationale observationnelle prospective comparative JUMODA","authors":"Thomas Schmitz , François Goffinet","doi":"10.1016/j.gofs.2023.11.005","DOIUrl":"10.1016/j.gofs.2023.11.005","url":null,"abstract":"<div><h3>Objectives</h3><p>To summerize the results of the JUMODA study (JUmeaux MODe d’Accouchement) on the planned mode of delivery of twin pregnancy and the management of second twin delivery.</p></div><div><h3>Methods</h3><p>JUMODA was a national observational prospective comparative study that took place between february 2014 and march 2015 in 176 french maternity units performing more than 1500 deliveries per year. Its main objectives were the comparison of neonatal and maternal morbidity according to the planned mode of delivery and the determination of the managements of second twin delivery associated with the best neonatal outcomes. To control for potential confounding factors and indication biases, statistical analyses comprized multivariate logistic regressions and matching on propensity scores.</p></div><div><h3>Results</h3><p>The JUMODA study recruited 8823 women with twin delivery at or beyond 22 weeks of gestation. For twin pregnancies with a cephalic first twin at 32 weeks of gestation and beyond, severe neonatal morbidity was higher in the planned cesarean (150/2908 (5.2 %) than in the planned vaginal delivery group (199/8922 (2.2 %), aOR 1.56, 95 % CI 1.19-2.04). Increased neonatal morbidity in the planned cesarean delivery group was explained by higher severe morbidity in neonates born preterm (aOR 1.64, 95 % CI 1.13-2.39, for deliveries between 32<sup>+0</sup> and 34<sup>+6</sup> weeks of gestation, aOR 2.04, 95 % CI 1.22-3.41, for deliveries between 35<sup>+0</sup> SA and 36<sup>+6</sup> weeks of gestation) but not in neonates born at term (aOR 1.19, 95 % CI 0.58-2.44). In comparison with planned cesarean delivery, planned vaginal delivery was not associated with increased severe neonatal morbidity in case of breech presenting first twin after 32 weeks of gestation or with decreased survival witout severe neonatal morbidity in case of delivery before 32 weeks of gestation whatever the first twin presentation. In comparison with planned vaginal delivery, planned cesarean delivery was associated with increased severe maternal morbidity only in women aged 35 and higher. Delivery of non cephalic second twin was associated with similar severe neonatal morbidity rate than delivery of cephalic second twin. Finally, in case of cephalic second twin, internal version followed by total breech extraction was associated with less cesarean for the second twin but with higher severe neonatal morbidity in case of preterm birth in comparison with pushing efforts, ocytocin perfusion and artificial rupture of membranes.</p></div><div><h3>Conclusions</h3><p>Planned vaginal delivery is the planned mode of delivery to encourage for the majority of pregnant women with twins, whatever first twin presentation and gestational age at delivery. No management of cephalic second twin appears better than an other, its choice will rest on obstetrician preferences.</p></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 6","pages":"Pages 410-417"},"PeriodicalIF":0.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Geoffroy Robin (Coordonnateur national de la FST Médecine et Biologie de la Reproduction – Andrologie)
{"title":"Conséquences de la réforme du 3e cycle des études médicales sur l’accès à la formation en médecine de la reproduction","authors":"Geoffroy Robin (Coordonnateur national de la FST Médecine et Biologie de la Reproduction – Andrologie)","doi":"10.1016/j.gofs.2024.05.003","DOIUrl":"https://doi.org/10.1016/j.gofs.2024.05.003","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 6","pages":"Pages 381-383"},"PeriodicalIF":0.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141294570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"La cholestase gravidique : pour une vision holistique de la femme. À propos des examens complémentaires lors du diagnostic","authors":"Jeremy Boujenah","doi":"10.1016/j.gofs.2024.02.023","DOIUrl":"10.1016/j.gofs.2024.02.023","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 6","pages":"Page 427"},"PeriodicalIF":0.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139974756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karima Mekni , Meriam Baba , Ines Haddad , Monia Aaraar , Oumayma Mejri , Chiraz ElFekih
{"title":"Applicabilité de l’Adnex score dans la prédiction de la malignité des kystes ovariens","authors":"Karima Mekni , Meriam Baba , Ines Haddad , Monia Aaraar , Oumayma Mejri , Chiraz ElFekih","doi":"10.1016/j.gofs.2023.12.001","DOIUrl":"10.1016/j.gofs.2023.12.001","url":null,"abstract":"<div><h3>Objective</h3><p>Ovarian cancer screening is a difficult problem due to the anatomy of the ovaries. Only histology allows a definite diagnosis. Our objective was to study the contribution of the Adnex score in the histological characterization of adnexal images for adequate management.</p></div><div><h3>Methods</h3><p>It was a retrospective, mono-center, descriptive and analytical. Sixty-five patients were included, those operated for an ovarian cyst and meeting the Adnex criteria: clinical, ultrasound and laboratory.</p></div><div><h3>Results</h3><p>The mean age of the patients was 38.6 years. They were nulliparous in 43 % of cases, and only four had a history of operation on ovarian cyst. Abdominal pelvic pain was the most frequent reason for consultation in 48 % of cases. An abdominopelvic mass was found on abdominal examination in 11 % of cases. Pelvic ultrasound made it possible to objectify the presence of an ovarian mass in all cases, with an average size of 79.66<!--> <!-->mm and a reassuring appearance in 66 % of cases. The calculation of the Adnex score was done in all patients preoperatively, for a 10 % cut-off, the model showed an 86 % chance of benignity for tumors proven to be histologically benign. The main route of entry was laparoscopy, in 61 % of cases. The treatment was in most cases conservative consisting essentially of a cystectomy.</p></div><div><h3>Conclusion</h3><p>The Adnex score discriminated well between benign and malignant masses, allowing for a better diagnosis preoperatively. It thus deserves its applicability in the clinical setting.</p></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 6","pages":"Pages 398-402"},"PeriodicalIF":0.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138812318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aurélie Reitz , Marion Rouzaire , Romain Cahierc , Bruno Pereira , Richard Lemal , Cyril Garrouste , Denis Gallot
{"title":"Devenir obstétrical des patientes transplantées rénales suivies dans une maternité de type III. Étude rétrospective de 2000 à 2020","authors":"Aurélie Reitz , Marion Rouzaire , Romain Cahierc , Bruno Pereira , Richard Lemal , Cyril Garrouste , Denis Gallot","doi":"10.1016/j.gofs.2024.01.011","DOIUrl":"10.1016/j.gofs.2024.01.011","url":null,"abstract":"<div><h3>Aim</h3><p>To describe pregnancy outcome of kidney transplant patients till 1 year postpartum.</p></div><div><h3>Methods</h3><p>This retrospective, monocentric study included 15 kidney transplant patients who presented 18 pregnancies, between January 2000 and January 2020. For each of them, we searched for possible obstetrical, fetal and renal complications and we evaluated renal function before, during and after pregnancy.</p></div><div><h3>Results</h3><p>The live birth rate was 84% (16/19) with an average gestational age at delivery of 37 weeks of gestation. The rate of prematurity was 50% (8/16), gestational diabetes was 16.6% (3/18) and preeclampsia was 27.7% (5/18). Cesarean section was performed in 61.1% (11/18) of cases including, 81.8% (9/11) unplanned surgery. The average birth weight was 2635 grams and 37.5% (6/16) of the newborn were small for gestational age. All patients had stable renal function before conception of pregnancy. We noticed two acute graft rejection during pregnancy with only one resulting in graft loss. Four patients had a reduced graft function in 12<!--> <!-->months of the postpartum.</p></div><div><h3>Conclusion</h3><p>Risk of maternal, fetal and renal complications remained high in kidney transplant recipients. Pregnancy should be carefully planned in transplanted women associated with adequate follow-up according to clinical guidelines (normal renal function and blood pressure without proteinuria before pregnancy, no recent graft rejection, period of one year after transplant respected and no teratogenic treatment in the month before pregnancy).</p></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 6","pages":"Pages 391-397"},"PeriodicalIF":0.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139687813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}