Hélène Thomas, Marie Zilliox, Nicolas Sananes, Julien Todeschi, Hugo Andres Coca, Isabelle Talon, Anne Sophie Weingertner
{"title":"[Limited dorsal myeloschisis: from antenatal screening to postnatal evolution. About a series of cases from the Grand Est, Bourgogne and Franche Comté].","authors":"Hélène Thomas, Marie Zilliox, Nicolas Sananes, Julien Todeschi, Hugo Andres Coca, Isabelle Talon, Anne Sophie Weingertner","doi":"10.1016/j.gofs.2025.05.004","DOIUrl":"https://doi.org/10.1016/j.gofs.2025.05.004","url":null,"abstract":"<p><strong>Introduction: </strong>Limited dorsal myeloschisis (LDM) is a rare closed neural tube defect characterized by the presence of a fibroneural rod connecting the spinal cord to the skin, and a focal closed skin defect. Distinguishing between open and closed forms of dysraphism is a major challenge, given their variable prognosis. However, the diagnosis of LDM in the ante-natal period is difficult and the prognosis of children is little studied, although these data are vital in order to establish suitable prenatal advice and provide couples with the best possible support.</p><p><strong>Material and methods: </strong>We conducted a retrospective multicenter observational study from May 2010 to March 2023 on 5 reference centers attached to a prenatal diagnosis center: the university hospital centers (CHU) of Besançon, Dijon, Nancy, Reims and Strasbourg.</p><p><strong>Results: </strong>A total of 21 cases of LDM suspected on reference ultrasonography were included. The ultrasound criteria used were standardized and corresponded to those described in the literature. In 76% of cases, MRI was performed to complement the obstetrical ultrasound. Amniocentesis was performed in over 50% of cases, and was always normal. Of the 21 cases initially suspected prenatally, there were 17 live births: 9 confirmed cases of LDM (52.9%), and 8 invalidated cases (47.1%), corresponding to another diagnosis. Of the 9 confirmed cases of LDM, 8 were isolated forms, and 1 was associated with a poly malformative syndrome (VACTERL). On reference ultrasonography, there were no significant differences in criteria between confirmed and invalidated LDM, apart from the fibroneural stalk described sonographically in 2 cases, both confirmed postnatally. Concerning the spinal level, there was a difference in involvement, with a predominance of the lumbar level in confirmed cases of LDM, whereas a sacral level was preferred among infirm cases. MRI was carried out in 76% of cases, and confirmed the diagnosis of LDM in 71% of confirmed cases in the postnatal period. Of the 5 requests for medical termination of pregnancy (MTP), 3 were accepted, but 2 were refused by the CPDPN. These two cases corresponded to a confirmed postnatal isolated LDM and a lipomyelomeningocele, both with a favorable prognosis and evolution. Post-natal follow-up averaged 32 months. No notable neurological abnormalities were noted. In terms of bladder and bowel function, urinary tract infections and constipation were common but rare (n=3/6; 50%) and not severe. No significant psychomotor retardation was reported. The 8 cases of invalidated LDM all corresponded to closed dysraphism. No diagnosis was corrected to open dysraphism.</p><p><strong>Conclusion: </strong>In contrast to myelomeningocele, our study confirms that limited dorsal myeloschisis (LDM) tends to have a good prognosis. However, given the risk of postnatal symptoms, particularly sphincter symptoms, management must be early and multidisciplinary","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julie Marcadet, Camille Legros, Guillaume Gavaudan, Vincent Balaya, Malik Boukerrou, Phuong Lien Tran
{"title":"[Operating room: two concrete actions for a lasting impact on environment].","authors":"Julie Marcadet, Camille Legros, Guillaume Gavaudan, Vincent Balaya, Malik Boukerrou, Phuong Lien Tran","doi":"10.1016/j.gofs.2025.05.002","DOIUrl":"https://doi.org/10.1016/j.gofs.2025.05.002","url":null,"abstract":"<p><strong>Introduction: </strong>The management of medical waste is critical for hospitals and environmental authorities, particularly in isolated regions like Réunion Island. In 2022, the CHU Sud Réunion generated over 147.5 tons of infectious medical waste (DASRI) and 1,203 tons of industrial waste. The study investigates the effect of awareness campaigns and pricing transparency in reducing waste production in operating rooms.</p><p><strong>Materials and methods: </strong>This prospective intervention study involved healthcare professionals from 14 operating rooms at CHU Sud. Two interventions were implemented: posters educating on waste segregation and labels displaying the cost of medical devices (MD) to reduce overuse. Waste was weighed, and the quality of sorting assessed at four time points.</p><p><strong>Results: </strong>The quality of waste sorting improved, particularly for DAOM (non-infectious waste), where compliance increased from 52.8% at baseline to 79% after three months. However, sorting for DASRI remained challenging, with a decrease in compliance from 54.2% to 36%. Waste volume decreased by 38.2% after the second intervention.</p><p><strong>Conclusion: </strong>While awareness improved sorting, DASRI management requires further action. Training and regular audits are needed. The inclusion of MD prices helped reduce waste, mirroring findings in other studies. Simple interventions led to better waste management and reduced total waste in operating rooms. Continued efforts, including long-term training and specialized waste committees, are essential for ongoing improvement.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Optimization of cervical cancer screening in France: A prospective multicenter clinical study].","authors":"Ameline Bénard, Shukofa Alipour, Frédéric Mauny, Marine Grillot, Marion Bonvalot, José-Philippe Moreno","doi":"10.1016/j.gofs.2025.05.001","DOIUrl":"10.1016/j.gofs.2025.05.001","url":null,"abstract":"<p><strong>Objectives: </strong>In France, the rate of cervical cancer screening (CCS) coverage is estimated to be 53.4% in 2022 with a target of 80%. This study assessed the effectiveness of a strategy involving telephone reminders by general practitioners (GPs) to increase participation.</p><p><strong>Methods: </strong>This prospective, descriptive multicenter study was conducted in France in 2023. Eight hundred and thirty-one women aged between 25 and 65 years did not undergo up-to-date screening according to French recommendations and were contacted by a healthcare professional in the medical practices where they were followed up to schedule a screening appointment. The rate of patient participation in CCS for each GP was recorded before and after the inclusion period using the website (www.amelipro.fr). This study was approved by the French Data Protection Authority (Commission Nationale de l'Informatique et des Libertés) under No. 2227553 v. 0.</p><p><strong>Results: </strong>The rate of participation in CCS increased from 53.4 to 63.8% following telephone calls of eligible patients who were not up-to-date with their screening. After receiving a telephone call, patients over 50 years of age had an acceptance rate similar to that of patients under 50 years of age despite their lower screening coverage.</p><p><strong>Conclusions: </strong>This study highlights the importance of personalized medicine for reducing inequalities. This measure is complementary to preexisting measures, such as organized screening, or planned measures, such as vaginal self-sampling.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucas Cacciatore, Chris Minella, Bruno Langer, Anne-Sophie Weingertner, Virginie Collin-Bund
{"title":"[Left ventricular hypertrabeculation discovered during pregnancy simultaneously in the mother and the fetus].","authors":"Lucas Cacciatore, Chris Minella, Bruno Langer, Anne-Sophie Weingertner, Virginie Collin-Bund","doi":"10.1016/j.gofs.2025.04.005","DOIUrl":"10.1016/j.gofs.2025.04.005","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mathilde Bourdon, Camille Artru, Anna Molto, Mathilde Barrois, Chloé Maignien, Catherine Patrat, Charles Chapron, Pietro Santulli
{"title":"[Chronic inflammatory rheumatic diseases and female fertility].","authors":"Mathilde Bourdon, Camille Artru, Anna Molto, Mathilde Barrois, Chloé Maignien, Catherine Patrat, Charles Chapron, Pietro Santulli","doi":"10.1016/j.gofs.2025.04.004","DOIUrl":"https://doi.org/10.1016/j.gofs.2025.04.004","url":null,"abstract":"<p><p>Chronic inflammatory rheumatic diseases (CIRDs) are a group of diseases responsible for inflammatory joint pains and can affect young women with a desire to conceive. CIRDs can impact female fertility, although the exact effects are still not fully understood. Some studies report reduced fertility, particularly due to prolonged conception delays, which are related to multiple factors. Among these, sexual dysfunction is common due to pain and chronic fatigue. The impact of CIRDs on ovarian reserve remains controversial. Regarding treatments, disease-modifying drugs have not shown a deleterious effect on fertility, but certain teratogenic treatments should be avoided in women who wish to conceive. Furthermore, there appears to be an association between CIRDs and some gynecological conditions known causes of infertility. For patients with CIRDs, early discussion about fertility is necessary. In the case of a desire for pregnancy, preconception consultation is essential to adjust treatments, manage risks, and prepare for pregnancy under the best possible conditions. In cases of proven infertility, assisted reproductive technology is a therapeutic option. Some studies suggest that success rates may be lower than those observed in the general population. A multidisciplinary approach involving rheumatologists, gynecologists, and reproductive specialists, as well as therapeutic optimization during the preconception period, is crucial to improve the chances of conception and provide appropriate follow-up for these patients.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Obstetrical and neonatal outcomes of women intending to give birth in a Birth Center: A single-center retrospective study].","authors":"Manon Verdin, Julien Simon, Emilie Gauchotte, Olivier Morel, Gaëlle Ambroise Grandjean, Matthieu Dap","doi":"10.1016/j.gofs.2025.04.003","DOIUrl":"https://doi.org/10.1016/j.gofs.2025.04.003","url":null,"abstract":"<p><strong>Objectives: </strong>The main objective is to describe the obstetric and pediatric outcomes of patients intending to give birth at the Nancy Birth Center (BC).</p><p><strong>Methods: </strong>This was a single-center retrospective study including all women who intended to give birth at the BC between 2020 and 2022. Outcomes were described according to the place of birth and the timing of transfer: the groups \"antepartum transfer\" and \"intended birth at the BC\". The latter group consisted of the subgroups \"birth at the BC » and \"intrapartum transfer\". Obstetric and neonatal outcomes were described using composite morbidity scores.</p><p><strong>Results: </strong>Out of 383 women, 33.9% (n=13/383) were transferred antepartum, 39.1% (n=150/383) were monitored at the BC and gave birth there without transfer, 16.1% (n=62/383) were transferred intrapartum, and 10.7% (n=41/383) were transferred postpartum. The maternal morbidity rate was 46.1% in the antepartum transfer group, 61.3% in the intrapartum transfer group, and 1.5% in the birth at the BC group. Neonatal morbidity rates were 8.4%, 11.3%, and 0.5%, respectively.</p><p><strong>Conclusion: </strong>The defined eligibility criteria help to select women at lower obstetric risk. However, maternal and neonatal complications remain possible. Collaboration and proximity between the BC and the obstetric unit are essential.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Artificial intelligence and civil liability in cancerology: The breast cancer example].","authors":"Marine Bricout, Camilo Adem, Remy J Salmon","doi":"10.1016/j.gofs.2025.04.002","DOIUrl":"https://doi.org/10.1016/j.gofs.2025.04.002","url":null,"abstract":"<p><p>For some years now, artificial intelligence has been investing in the field of healthcare, in both technical and clinical disciplines. While this technological advance represents a real opportunity for the doctors of today and tomorrow, the fact remains that it is a new entity that needs to be understood, supervised and tested before it can become a real ally. Through a few examples drawn from our clinical practice in senology, we have identified the issues that artificial intelligence could raise in terms of civil liability, during legal procedures. How can we deal with claims arising from the use of artificial intelligence, and how can we clearly identify those who will bear responsibility for any damage caused?</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}