Gynecologie Obstetrique Fertilite & Senologie最新文献

{"title":"[Let's continue to differentiate VaIN 2 from VaIN 3: a study on the progression of a series of 54 cases of VaIN 2].","authors":"Paul Hag, Victor Gabriele, Camille Martel, Massimo Lodi, Jean Jacques Baldauf, Lise Lecointre","doi":"10.1016/j.gofs.2026.09.006","DOIUrl":"https://doi.org/10.1016/j.gofs.2026.09.006","url":null,"abstract":"<p><p>Objective : Vaginal intraepithelial neoplasias (VaIN) are rare pre-cancerous lesions of the female genital tract caused by human papillomaviruses (HPV) (1). Their risk of progression to actual vaginal cancer is estimated between 3% and 12% (2, 5). Since the new 2020 terminology of the World Health Organization (WHO) on high-grade VaIN, gathering VaIN 2 and 3, the recommended management is the same (6). However, the progression of these histopathological entities would be very different, which is why we wanted to study the outcome of VaIN 2 cases followed in our department, depending on whether the management was active through laser destruction, Imiquimod, or surgical excision, or if close monitoring was preferred. Materials and Methods : We conducted a retrospective monocentric study between 1990 and 2024. All patients diagnosed with VaIN 2 and followed for at least 2 years were included. Results : Fifty-four patients were included, one-third of whom were initially monitored, and the average follow-up duration was 54.8 ± 26.8 months. The average age at diagnosis was 52.6 ± 15.9 years, with a history of smoking found in 40% of the patients, immunosuppression in a quarter of them, and 22% of the patients had an HPV 16 or 18 infection. A favorable outcome was found in 66.7% of the monitored cases and in 81.8% of the actively treated cases. There was no significant difference in the progression profiles with p equal to 0.14. There was also no significant difference in event-free survival with p equal to 0.10. Conclusion : Expectant management does not appear to be associated with an increased risk of unfavorable progression compared with ablative treatment. It therefore seems reasonable to propose an appropriate initial surveillance strategy. VaIN 2 lesions appear to have a predominant rate of spontaneous regression, which may call into question the relevance of grouping all high-grade VaIN lesions together.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149149830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Quality and reliability of YouTube videos on induction of labour: a descriptive crosssectional study].","authors":"Elodie Vignozzi, Faustine Tellier, Astrid Eckman-Lacroix, Camille Nallet, Romaine Bassi, Louise Lucot-Royer, Nicolas Mottet, Marine Lallemant","doi":"10.1016/j.gofs.2026.10.001","DOIUrl":"https://doi.org/10.1016/j.gofs.2026.10.001","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the quality and reliability of French-language YouTube videos on induction of labour, and to investigate whether their quality is related to their popularity.</p><p><strong>Methods: </strong>Descriptive cross-sectional study conducted from May to August 2023. The first 30 videos returned for each of four non-technical keywords were assessed independently and blindly by two reviewers using the DISCERN score (range 16-80), the primary outcome. Popularity was assessed by the number of views and the Video Power Index (VPI).</p><p><strong>Results: </strong>Of the 120 videos identified, 17% (n = 20) were included. A healthcare professional appeared in 75% of the videos (n = 15). The median DISCERN score was 54.3 [47.3-59.8]: 65% of the videos (n = 13) were of good or excellent quality and 20% (n = 4) of poor quality. Inter-rater reliability was excellent (intraclass correlation coefficient: 0.92). Sources and the date of the information were rarely mentioned. The DISCERN score was correlated neither with the number of views (p = 0.97) nor with the VPI (p = 0.83). Good-quality videos more often described the indications for induction (92% vs 43%; p = 0.03).</p><p><strong>Conclusion: </strong>These videos are scarce and of heterogeneous quality, and their popularity does not reflect their quality. Healthcare professionals should direct patients towards identified content, all the more so as the rise of artificial intelligence reinforces the need for certified sources.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[CO2 utilization in minimally invasive surgery].","authors":"Luane Grondin, Clemence Lolon, Julie Marcadet, Victoria Fontaine, Malik Boukerrou, Vincent Balaya, Phuong Lien Tran","doi":"10.1016/j.gofs.2026.09.011","DOIUrl":"https://doi.org/10.1016/j.gofs.2026.09.011","url":null,"abstract":"<p><strong>Objective: </strong>Over the course of a year, in a medium-sized operating theatre, the amount of CO₂ used to create an intra-abdominal pneumoperitoneum during minimally invasive surgical procedures is equivalent to the emissions produced by driving round the world along the equator. The aim of this study was to determine the factors influencing CO₂ consumption.</p><p><strong>Materials and methods: </strong>We conducted a single-centre, retrospective observational study at the CHU Sud Réunion, aimed at analysing the factors influencing CO₂ consumption in the operating theatre during minimally invasive surgery. This was supplemented by a descriptive prospective analysis carried out over a one-week period across all operating theatres, during which CO₂ consumption of each minimally invasive intervention was recorded every two minutes from the time of incision until closure, whilst noting any complications arising during the procedure.</p><p><strong>Results: </strong>The observational study involved 521 patients who underwent surgery during the study period in the operating theatre of the CHU Sud de Saint-Pierre. The volume of CO₂ insufflated ranged from 21 L to 50 L for a vNOTEs salpingectomy up to 903 L for a robotic hysterectomy. CO₂ consumption was strongly associated with operative time (p < 0.001) and intra-abdominal insufflation pressure (p = 0.004). The descriptive study of 23 patients revealed avoidable CO₂ consumption, mainly due to valves not being fully closed or to the continuation of insufflation when it was no longer necessary for the procedure to continue.</p><p><strong>Conclusion: </strong>CO₂ consumption in the operating theatre depends mainly on technical and organisational factors, rather than on patient characteristics. The entire operating theatre team must be made aware of environmental issues, as every action counts towards reducing our carbon footprint.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149119018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[How I do … partial breast reconstruction with the LICAP flap in five steps].","authors":"Lou Donval, Anne Sabaila","doi":"10.1016/j.gofs.2026.09.009","DOIUrl":"https://doi.org/10.1016/j.gofs.2026.09.009","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149119066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Does the SOLENCE application improve the quality of life of patients with polyendocrine metabolic ovarian syndrome?]","authors":"Clarisse Outreman, Violette Heems, Camille Ternynck, Anne-Laure Rolland, Pauline Plouvier, Geoffroy Robin, Sophie Catteau-Jonard","doi":"10.1016/j.gofs.2026.09.010","DOIUrl":"https://doi.org/10.1016/j.gofs.2026.09.010","url":null,"abstract":"<p><strong>Objective: </strong>A digital health application dedicated to polyendocrine metabolic ovarian syndrome (PMOS), the SOLENCE application, was offered to patients diagnosed with PMOS according to the Rotterdam criteria at a University Hospital. We seek to evaluate the impact of the SOLENCE application on patients' quality of life. METHODS : Questionnaires assessing the quality of life of PMOS patients, their anxiety, depression, and sexual satisfaction before and after 6 months of using the app were compared. The inclusion period was from November 2023 to December 2024. The questionnaire consisted of four validated sub-questionnaires: PCOSQOL (Polycystic Ovary Syndrome Quality of Life), HADS (Hospital Anxiety and Depression Scale), ASEX (Arizona Sexual Experience Scale), and FACT-G7 (Functional Assessment of Cancer Therapy - General - 7 Item Version).</p><p><strong>Results: </strong>A total of 54 patients were included. After comparing the questionnaires before and after using the app, only the FACT-G7 questionnaire, which assesses overall quality of life in the monitoring of chronic diseases showed a statistically significant worsening. The lack of statistical power due to the small sample size may partially explain these results. In addition, the patients who logged in most frequently felt that the SOLENCE app could have a place in the medical monitoring of PMOS patients. CONCLUSION : The SOLENCE app does not appear to provide any benefit to our patients with PMOS. Further studies are needed to investigate the improvement in PMOS symptoms between users and non-users of the app, which has since been updated to offer more personalized content.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149119042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment je fais… l’analyse du chiasma et des voies optiques en prénatal ?","authors":"Marie Brasseur-Daudruy,&nbsp;Clémence Klapczynski,&nbsp;Eric Verspyck","doi":"10.1016/j.gofs.2026.03.004","DOIUrl":"10.1016/j.gofs.2026.03.004","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"54 10","pages":"Pages 513-516"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147494855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effets hémodynamiques et cliniques du système intra-utérin au lévonorgestrel dans l’adénomyose symptomatique : étude prospective par écho-Doppler","authors":"Eda Adeviye Şahin,&nbsp;Turan Şahin,&nbsp;Hanifi Şahin,&nbsp;Tuncay Küçüközkan","doi":"10.1016/j.gofs.2026.05.005","DOIUrl":"10.1016/j.gofs.2026.05.005","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate clinical, hematological, and uterine hemodynamic outcomes after levonorgestrel-releasing intrauterine system (LNG-IUS) insertion in women with symptomatic adenomyosis associated with heavy menstrual bleeding.</div></div><div><h3>Methods</h3><div>This prospective observational study included premenopausal women aged<!--> <!-->≥<!--> <!-->30 years with sonographically diagnosed adenomyosis based on recognized sonographic features consistent with descriptors later formalized in the revised MUSA consensus statement. Menstrual blood loss assessed by the Pictorial Blood Loss Assessment Chart (PBAC), pain severity assessed by Visual Analog Scale (VAS), hematological parameters, uterine volume, and uterine artery Doppler indices — including resistance index (RI) and pulsatility index (PI) — were evaluated before LNG-IUS insertion and after 12 months of follow-up. Pre- and post-treatment comparisons were performed using paired statistical tests.</div></div><div><h3>Results</h3><div>Sixty-five patients completed the 12-month follow-up. PBAC scores decreased significantly (169.6<!--> <!-->±<!--> <!-->49.6 vs. 42.4<!--> <!-->±<!--> <!-->20.6; <em>P</em> <!-->&lt;<!--> <!-->0.001) as did VAS pain scores (4.2<!--> <!-->±<!--> <!-->1.8 vs. 2.4<!--> <!-->±<!--> <!-->0.8; <em>P</em> <!-->&lt;<!--> <!-->0.001). Hemoglobin and hematocrit levels increased significantly (<em>P</em> <!-->&lt;<!--> <!-->0.001). A significant reduction in uterine volume was observed (161.3<!--> <!-->±<!--> <!-->33.5<!--> <!-->mL vs. 123.0<!--> <!-->±<!--> <!-->28.0<!--> <!-->mL; <em>P</em> <!-->&lt;<!--> <!-->0.001). Uterine artery PI values did not change significantly, whereas RI values increased significantly on both sides (<em>P</em> <!-->&lt;<!--> <!-->0.001). No significant correlations were identified between RI changes, PBAC score reduction, and uterine volume reduction. Amenorrhea occurred in 21.5% of patients at 12 months. No cases of pelvic inflammatory disease or ovarian cyst formation were observed.</div></div><div><h3>Conclusions</h3><div>In women with symptomatic adenomyosis, LNG-IUS treatment is associated with significant clinical and hematological improvement together with reduction in uterine volume at 12 months. The observed increase in uterine artery resistance indices suggests that hemodynamic alterations may contribute to bleeding reduction in addition to endometrial suppression, although this relationship remains exploratory. LNG-IUS appears to be an effective, well-tolerated, and uterus-preserving treatment option for symptomatic adenomyosis.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"54 10","pages":"Pages 487-494"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148037877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profils des marqueurs sériques maternels de la trisomie 21 : révision des commentaires et des conduites à tenir","authors":"Gilles Renom,&nbsp;Magali Pettazzoni,&nbsp;Jean Guibourdenche,&nbsp;Corinne Sault,&nbsp;Valérie Moal,&nbsp;Alain Liquier,&nbsp;Safouane Hamdi,&nbsp;Simon Samaan,&nbsp;Étienne Voirin-Mathieu,&nbsp;Fabienne Artur,&nbsp;Jérôme Massardier,&nbsp;Véronique Debarge,&nbsp;ABA","doi":"10.1016/j.gofs.2026.04.002","DOIUrl":"10.1016/j.gofs.2026.04.002","url":null,"abstract":"<div><div>In France, for the vast majority of patients, screening for Down syndrome using circulating cell-free fetal DNA is contingent upon prior assessment of maternal serum markers and calculation of a specific risk estimate for this aneuploidy. Certain marker profiles may also suggest other fetal or maternal pathologies. This article therefore aims: (i) to clarify and explain any comments that may appear in laboratory reports; (ii) to propose a clinical interpretation and a procedure to be followed for the monitoring of the considered pregnancy. It updates a first article published in 2014 and, like its predecessor, reflects broad consensus among the biologists authorised to perform this screening.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"54 10","pages":"Pages 501-508"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact de la prise en charge ambulatoire sur le taux de transfusion pour hématomes post-mastectomies","authors":"Valentine Cordonnier,&nbsp;Frédérique Forestier,&nbsp;Marie Gilles-Baray,&nbsp;Dragos Georgescu,&nbsp;Marie Ottaviani","doi":"10.1016/j.gofs.2026.07.002","DOIUrl":"10.1016/j.gofs.2026.07.002","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study is to evaluate the impact of outpatient management on the transfusion rate of blood products for post-mastectomy hematoma since the implementation of the Nursing Support and Post Ambulatory Follow-up Device at Home (DIASPAD).</div></div><div><h3>Method</h3><div>This is a retrospective monocentric observational study carried out January 1, 2011 and December 31, 2022, at the Henri Becquerel Center. It covers all adult women undergoing total mastectomy with or without associated axillary surgery, without breast reconstruction, who developed a hematoma requiring drainage within 30 days of the initial surgery. The study assesses the use of blood products during hematoma management and compares their use according to two distinct hospitalization modes: conventional hospitalization versus outpatient hospitalization.</div></div><div><h3>Results</h3><div>During the study period, 80 patients required revision surgery for post-mastectomy hematoma. Twenty-eight of them received a transfusion, i.e. 35%; with no significant difference between the two hospitalization groups: 37.1% in the outpatient group and 33.3% in the conventional group (<em>P</em> <!-->=<!--> <!-->0.72).</div></div><div><h3>Conclusion</h3><div>Performing mastectomies on an outpatient basis does not appear to have an impact on the utilization rate of blood products when complicated by hematoma.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"54 10","pages":"Pages 480-486"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148498560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sommaire","authors":"","doi":"10.1016/S2468-7189(26)00229-1","DOIUrl":"10.1016/S2468-7189(26)00229-1","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"54 10","pages":"Pages iii-iv"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149072019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}