Lisa Joulot, Jeanne Sibiude, Pierre Delorme, Anne Pinton
{"title":"Dépistage et prise en charge de la glycosurie mensuelle dans le suivi de la grossesse : étude des pratiques en France","authors":"Lisa Joulot, Jeanne Sibiude, Pierre Delorme, Anne Pinton","doi":"10.1016/j.gofs.2026.06.007","DOIUrl":"10.1016/j.gofs.2026.06.007","url":null,"abstract":"<div><h3>Objective</h3><div>Historically used for screening gestational diabetes, testing for glycosuria during pregnancy is now controversial. Despite the low diagnostic performance of this test, the “Haute Autorité de Santé” (HAS) recommends performing it at each prenatal visit. However, this practice represents an estimated annual cost of 2 million euros in France. The aim of this study was to evaluate French practices regarding glycosuria prescription and the management adopted by practitioners in case of a positive result.</div></div><div><h3>Materials and methods</h3><div>An observational study was conducted using a questionnaire distributed to healthcare professionals in France between August 31, 2024, and April 1, 2025. A univariate comparative analysis was performed according to whether glycosuria was prescribed or not, and according to the management implemented in cases of positive glycosuria.</div></div><div><h3>Results</h3><div>A total of 1132 responses were collected. Glycosuria was prescribed by 62% of respondents during pregnancy follow-up. In the event of a positive result, 45% of practitioners took no action, 45% prescribed screening for gestational diabetes using fasting blood glucose or an oral glucose tolerance test (OGTT), and 10% reinforced dietary and lifestyle advice during the consultation. Glycosuria prescription was significantly more frequent among midwives (<em>P</em> <!-->=<!--> <!-->0.04), practitioners working in private practice (<em>P</em> <!-->=<!--> <!-->0.01), in private healthcare facilities (<em>P</em> <!-->=<!--> <!-->0.04), and in type 1 maternity units (<em>P</em> <!-->=<!--> <!-->0.01).</div></div><div><h3>Conclusion</h3><div>Glycosuria continues to be prescribed by the majority of practitioners, but with highly heterogeneous practices across France and without evaluation of its effectiveness. Glycosuria testing is costly, and its performance in screening for gestational diabetes has not been demonstrated. Reassessment of its role in prenatal care in France appears necessary.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"54 10","pages":"Pages 470-474"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148406996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Willemart, Clémence Bongrand, Vincent Balaya, Julie Marcadet, Malik Boukerrou, Phuong Lien Tran
{"title":"Évaluer et améliorer la surveillance post-thérapeutique des lésions précancéreuses du col à La Réunion","authors":"Martin Willemart, Clémence Bongrand, Vincent Balaya, Julie Marcadet, Malik Boukerrou, Phuong Lien Tran","doi":"10.1016/j.gofs.2026.06.003","DOIUrl":"10.1016/j.gofs.2026.06.003","url":null,"abstract":"<div><h3>Objective</h3><div>Cervical cancer affects nearly 3000 women each year in mainland France and is responsible for over 1000 deaths. In Reunion Island, the incidence and mortality rates are higher than in mainland France. The National Cancer Institute recommends an HPV test 6<!--> <!-->months after treatment of a precancerous lesion. This study evaluates the practices of healthcare professionals in Reunion Island regarding these recommendations.</div></div><div><h3>Methods</h3><div>This retrospective study included all women who underwent surgery for a precancerous lesion between October 2019 and February 2021 in Reunion Island. Data were collected from several centers and included patient characteristics, treatment methods, and follow-up protocols. The primary objective was to assess the rate of HPV testing 6<!--> <!-->months post-treatment. The secondary objective was to evaluate HPV clearance.</div></div><div><h3>Results</h3><div>Among the 760 patients, 38.3% were lost to follow-up. Of the 469 patients who were followed, 46.9% underwent an HPV test, with 79.5% completing the test at 6<!--> <!-->months. HPV clearance at 6<!--> <!-->months after conization was 52.9%.</div></div><div><h3>Conclusion</h3><div>Post-treatment follow-up of patients in Reunion Island needs improvement. Less than half of the patients underwent HPV testing at 6<!--> <!-->months. Strict implementation of the recommendations could reduce the incidence and mortality rates of cervical cancer, which remain higher than in mainland France.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"54 10","pages":"Pages 475-479"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148279956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myolyse des fibromes utérins : efficacité et impact sur la qualité de vie","authors":"Julie Lafourcade, Jean-Philippe Lucot, Estelle Declas, Cassandra Chaldaureille, Romain Detchev","doi":"10.1016/j.gofs.2026.05.006","DOIUrl":"10.1016/j.gofs.2026.05.006","url":null,"abstract":"<div><h3>Objective</h3><div>Uterine fibroids are a common benign condition that causes pelvic symptoms and impairs quality of life. Myolysis, a minimally invasive technique for thermal destruction of fibroids, is a conservative alternative.</div></div><div><h3>Materials and methods</h3><div>Retrospective single-center study including 49 patients operated on at Saint-Vincent de Paul Hospital (Lille) between August 2021 and December 2024 for symptomatic fibroids (FIGO 2 to 6). Patients were treated with laparoscopic or vaginal myolysis under ultrasound guidance. The primary endpoint was the reduction in fibroid volume on MRI at 6<!--> <!-->months. Secondary endpoints included changes in VAS, HIGHAM, UFS-QOL (HRQL, SSS) scores.</div></div><div><h3>Results</h3><div>A total of 93 fibroids were treated. The median reduction in fibroid volume was significant: −15<!--> <!-->cm<sup>3</sup> [−29.3; −1.4], or −38.78% [−62.14; −6.02] of their volume (<em>P</em> <!--><<!--> <!-->0.0001). The VAS, HIGHAM, and SSS scores improved significantly, with a concomitant increase in HRQL (+24.46 points, <em>P</em> <!--><<!--> <!-->0.0001). The overall complication rate was 20.4%, including two major complications (grade 3B). Nine patients (18.4%) required repeat surgery for additional treatment.</div></div><div><h3>Conclusion</h3><div>Radiofrequency myolysis is a promising minimally invasive alternative for uterine fibroids, improving symptoms and quality of life, but prospective studies are needed to confirm its efficacy and safety and standardize its indications.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"54 10","pages":"Pages 465-469"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148220977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chorioamniotite et neurodéveloppement à long terme chez les enfants nés prématurés : que nous apprennent les données de la cohorte EPIPAGE-2 ?","authors":"Fanny Salmon, Mathilde Letouzey, Emeline Maisonneuve, Gilles Kayem","doi":"10.1016/j.gofs.2026.04.004","DOIUrl":"10.1016/j.gofs.2026.04.004","url":null,"abstract":"<div><div>In cases of premature birth, intrauterine inflammation is common and may be harmful to the developing brain. Three analyses from the EPIPAGE-2 national prospective population-based cohort were recently published. This review provides an overview of recent data on the association between birth in the context of clinical and/or histological chorioamnionitis and long-term neurodevelopment in preterm infants. A major strength of this work lies in the examination of neurodevelopment within a homogeneous birth context, in contrast to the majority of previous studies. Indeed, the various causes of prematurity are based on distinct pathophysiological mechanisms that may influence a child's neurodevelopment differently. This limitation may partially account for the divergence observed with previous publications. These three studies included, from the EPIPAGE-2 cohort, children born alive between 24 and 34 weeks of gestation, following spontaneous labor or premature rupture of membranes. Clinical chorioamnionitis and histological chorioamnionitis, diagnosed after a standardized placental examination, were studied separately. The children's neurodevelopment was assessed at 2 and 5 years of age using standardized tools. At 2 years of age, clinical chorioamnionitis was associated with an increased risk of cerebral palsy (aOR<!--> <!-->=<!--> <!-->2.1; 95% CI: 1.1–4.1). In contrast, no significant association was observed between clinical chorioamnionitis and moderate-to-severe neurodevelopmental disorders at 5 years of age. Similarly, isolated histological chorioamnionitis was not associated with neurodevelopmental disorders at 2 or 5 years of age. Among children born prematurely following spontaneous labor or preterm rupture of membranes, exposure to clinical or histological chorioamnionitis does not appear to be associated with adverse neurodevelopmental outcomes at 5 years of age.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"54 10","pages":"Pages 495-500"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147824012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prise de paracétamol pendant la grossesse et troubles du neurodéveloppement de l’enfant : ce que les études de fratrie apportent, et les limites qui imposent une triangulation causale","authors":"Jérémy Boujenah","doi":"10.1016/j.gofs.2026.07.004","DOIUrl":"10.1016/j.gofs.2026.07.004","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"54 10","pages":"Pages 509-512"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucie Delaroche, Thomas Molher, Nicolas Le Fleuter, Thomas Fréour
{"title":"[ART laboratory networks: benefits, limitations and challenges].","authors":"Lucie Delaroche, Thomas Molher, Nicolas Le Fleuter, Thomas Fréour","doi":"10.1016/j.gofs.2026.09.007","DOIUrl":"https://doi.org/10.1016/j.gofs.2026.09.007","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149076754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susie Brousse, Lucas Freton, Katia Mahiou, Elisabeth Russ, Yann Delpech, Vincent Lavoué, Charlotte Vaysse, Carole Mathelin
{"title":"[Updated overview of transgender issues in France and beyond our borders].","authors":"Susie Brousse, Lucas Freton, Katia Mahiou, Elisabeth Russ, Yann Delpech, Vincent Lavoué, Charlotte Vaysse, Carole Mathelin","doi":"10.1016/j.gofs.2026.09.005","DOIUrl":"https://doi.org/10.1016/j.gofs.2026.09.005","url":null,"abstract":"<p><strong>Objectives: </strong>Transgender identity, defined as a lack of identification with the gender assigned at birth, has always existed, across different cultures and throughout history. While greater acceptance has led to an increase in the number of people identifying as transgender, training for healthcare professionals has not kept pace with this societal change. Our review aims to answer the main questions asked by healthcare professionals who have to care for trans and/or non-binary people.</p><p><strong>Materials and methods: </strong>We conducted a critical analysis of data from international literature, focusing mainly on the last five years. Based on the 55 publications selected, we sought to answer the six most frequently asked questions by healthcare professionals about transgender identity.</p><p><strong>Results: </strong>We reviewed 1) the essential definitions of biological sex, gender, sexual orientation, and different gender identities, 2) the evolution of the recognition of transgender people and their depathologization in the International Classification of Diseases, 3) the evolution of comprehensive care (including the introduction of ALD 31) and legislative changes, 4) geographical and temporal variations in transgender identities, 5) possible medical and surgical treatments (gender-affirming hormone therapy, various surgical treatments, fertility preservation, psychological support), 6) the need to address the lack of training for healthcare professionals on the subject of transgender identities.</p><p><strong>Conclusion: </strong>A good understanding of transgender identities and their epidemiological, legislative, medical, and psychological developments is essential to improve the quality of their care. Providing information to specialized healthcare professionals, gynecologists, and midwives on the reception and care of transgender people should lead to less discrimination and more appropriate and widespread therapies and preventive measures than are currently available.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anaïs de Crevoisier, Thibault Thubert, Maxime Chaillot
{"title":"[Prescribing menopausal hormone therapy by general practice residents: knowledge and training].","authors":"Anaïs de Crevoisier, Thibault Thubert, Maxime Chaillot","doi":"10.1016/j.gofs.2026.09.002","DOIUrl":"https://doi.org/10.1016/j.gofs.2026.09.002","url":null,"abstract":"<p><p>Objective - Menopausal hormone therapy (MHT) is currently the first-line treatment for vasomotor symptoms and for the prevention of bone loss in recently menopausal women at risk of fracture, according to current CNGOF/GEMVi recommendations. Despite this, its use remains limited in France. The primary objective of this study is to assess the frequency of MHT prescription among medical residents in general practice and to identify the factors associated with this prescription. Materials and methods- Cross-sectional descriptive and analytical study conducted from April to November 2023 among two GPR cohorts (2019-2022 and 2020-2023) at Nantes Faculty of Medicine (n=215). Data were collected using an anonymous online questionnaire (26 items) assessing gynecological training, MHT knowledge, self-reported prescription practices, and training needs. Statistical analyses were descriptive with between-group comparisons using non-parametric tests (χ², Mann-Whitney, p<0.05). Results- Sixty-two GPRs responded (29% response rate), 79% female. Eighty-four percent anticipated future gynecological activity in practice. Only 19.4% prescribed MHT first-line when indicated and without contraindications. Mean MHT knowledge score was 67%, with major gaps in indications (45%), contraindications (38%), and initial assessment (47%). Main prescription barriers were perceived lack of mastery (78%) and unfavorable benefit-risk perception (13%). MHT prescription was significantly more frequent among GPRs with gynecology rotations (40% vs 5%, p=0.001), specific theoretical training (32% vs 12%, p=0.06), or mentors favoring MHT (46% vs 12%, p=0.006). Ninety-eight percent reported insufficient menopause training. Conclusion- Limited MHT prescription propensity among GPRs, primarily linked to training deficits and mentor influence. Strengthening initial gynecological education and general practitioner-gynecologist collaboration appears essential to optimize menopause care in primary care.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}