Hélène Burgué , Philippe Trensz , Carole Mathelin , Anna Schohn
{"title":"Les forums de discussion dédiés au cancer du sein peuvent-ils être utiles aux soignants ? Analyse des messages initiaux du forum de la Ligue nationale contre le cancer pendant une année","authors":"Hélène Burgué , Philippe Trensz , Carole Mathelin , Anna Schohn","doi":"10.1016/j.gofs.2024.02.003","DOIUrl":"10.1016/j.gofs.2024.02.003","url":null,"abstract":"<div><h3>Objectives</h3><p>Forums are a source of health information and exchange. They can be studied to determine patients’ needs and improve caregivers’ practices. The aim of this study was to identify the needs of breast cancer patients based on messages posted on a discussion forum.</p></div><div><h3>Methods</h3><p>Initial messages posted in 2021 on the <em>Ligue nationale contre le cancer</em> (LNCC) breast cancer forum were analyzed quantitatively. Message content was classified into three categories: testimonial, request for advice or request for medical opinion. The tone of the message (positive, neutral, or negative) was recorded. The temporality of the illness during which the patient expressed herself was defined. Analysis was carried out on the initial messages using the Chi<sup>2</sup>, Fisher, and Kruskal-Wallis tests, with a significance level of<!--> <!--><<!--> <!-->0.05.</p></div><div><h3>Results</h3><p>In 2021, 640 initial messages posted on the LNCC forum dedicated to breast cancer were analyzed. Messages were posted by 312 authors, including 275 patients and 37 family members. Three main types of messages were identified: requests for medical advice (<em>n</em> <!-->=<!--> <!-->339), advice (<em>n</em> <!-->=<!--> <!-->164), and testimonials (<em>n</em> <!-->=<!--> <!-->137). Requests for medical advice elicited fewer responses than testimonials (<em>P</em> <!--><<!--> <!-->0.001). A need for supportive care was identified in 42.8% of messages, mostly concerning social (17.3%) and psychological (13%) care.</p></div><div><h3>Conclusion</h3><p>Our study revealed a need for more information especially regarding the social impact of the disease and the side-effects of treatment. The period of greatest need of information was the diagnostic waiting time. However, patients using discussion forums are not representative of all women with breast cancer and our results should not be generalized to all patients treated for breast cancer.</p></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 7","pages":"Pages 466-472"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139718095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clémence Dujardin , Thibault Balcaen , Antoine Vanoost , Denis Chatelain , Jean Gondry , Mathurin Fumery , Arthur Foulon
{"title":"Facteurs de risque de lésions malpighiennes intra-épithéliale de haut grade ou de cancer du col de l’utérus en cas de maladie inflammatoire chronique de l’intestin","authors":"Clémence Dujardin , Thibault Balcaen , Antoine Vanoost , Denis Chatelain , Jean Gondry , Mathurin Fumery , Arthur Foulon","doi":"10.1016/j.gofs.2024.01.008","DOIUrl":"10.1016/j.gofs.2024.01.008","url":null,"abstract":"<div><h3>Introduction</h3><p>Chronic inflammatory bowel disease (IBD) is thought to increase the risk of high-grade histological intraepithelial lesions (HGIL) and cervical cancer. The risk factors for developing these lesions are poorly understood.</p></div><div><h3>Materials and methods</h3><p>This is a single-center retrospective case-control study including IBD patients followed at our University Hospital Center from 2011 to 2021 who presented with HGIL or cervical cancer. Four controls were case-matched according to IBD type, age, active smoking and multiparity.</p></div><div><h3>Results</h3><p>Eighteen cases and 72 controls were included. We found no significant differences between the 2 groups with regard to mean age at IBD diagnosis, mean duration of IBD, IBD location, history of IBD-related surgery or even association with another chronic inflammatory disease. In our study, the use of immunosuppressants/biotherapies in these patients [50% (9/18) for cases vs. 56% (40/72) for controls; <em>P</em> <!-->=<!--> <!-->0.9] was not a risk factor for IGRA or cervical cancer. Similarly, neither the total duration of exposure to immunosuppressants/biotherapies (9.9<!--> <!-->±<!--> <!-->8<!--> <!-->years for cases vs. 6.6<!--> <!-->±<!--> <!-->5.3<!--> <!-->years for controls; <em>P</em> <!-->=<!--> <!-->0.1), nor combined therapies [11% (2/18) for cases vs. 6% (4/72) for controls; <em>P</em> <!-->=<!--> <!-->0.3], nor azathioprine or methotrexate use [22% (4/18) for cases vs. 11% (8/72) for controls; <em>P</em> <!-->=<!--> <!-->0.3] were found to be risk factors.</p></div><div><h3>Conclusion</h3><p>In our study, we found no risk factors for patients with IBD to develop IGRA or cervical cancer.</p></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 7","pages":"Pages 460-465"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468718924000126/pdfft?md5=6571d35b3659fdf91bc30a791741452e&pid=1-s2.0-S2468718924000126-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139547761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence de l’immersion dans l’eau sur le recours à la péridurale pendant le travail","authors":"Nesrine Kacha , Gwendoline Dorel , Paul Frappé , Céline Chauleur , Tiphaine Raia-Barjat","doi":"10.1016/j.gofs.2024.01.016","DOIUrl":"10.1016/j.gofs.2024.01.016","url":null,"abstract":"<div><h3>Objective</h3><p>Immersion in water during labor could reduce pain and use of epidural anesthesia during childbirth. The main objective of this study was to evaluate the influence of immersion in water during labor on the use of epidural anesthesia in a midwife care setting.</p></div><div><h3>Methods</h3><p>We conducted a single-center retrospective study of all women who gave birth in the physiological ward of Saint-Étienne University Hospital between October 2020 and December 2022.</p></div><div><h3>Results</h3><p>The study did not find difference between immersion group and control group concerning the use of epidural anesthesia (<em>P</em> <!-->=<!--> <!-->0.49). The immersion group counted more women with a duration of labor greater than 6<!--> <!-->hours than in the control group. The multivariate analysis adjusted for parity and duration of labor did not find difference between both groups [OR 0.58; 95% CI (0.30; 1.09)].</p></div><div><h3>Conclusion</h3><p>Even if it does not seem to modify the use of epidurals, immersion in water does not seem to increase maternal and neonatal morbidity and mortality. It represents a therapeutic alternative with reasonable cost to offer for pregnant women who wish to give birth without epidural anesthesia.</p></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 7","pages":"Pages 454-459"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139693640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Accouchement voie basse spontané compliqué d’un abcès du muscle ilio-psoas. À propos d’un cas et revue de la littérature","authors":"Asma Dali , Bilel Guidara , Jean-Daniel Hini","doi":"10.1016/j.gofs.2024.01.013","DOIUrl":"10.1016/j.gofs.2024.01.013","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 7","pages":"Pages 490-491"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139681950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emmanuelle Bodin , Romane Sainte-Rose , Claire Petit , Marion Cornuau , Fabrice Guérif
{"title":"Devenir clinique après transfert de blastocystes vitrifiés selon l’indication de congélation","authors":"Emmanuelle Bodin , Romane Sainte-Rose , Claire Petit , Marion Cornuau , Fabrice Guérif","doi":"10.1016/j.gofs.2024.06.002","DOIUrl":"10.1016/j.gofs.2024.06.002","url":null,"abstract":"<div><h3>Objectives</h3><div>In France, embryo thawing concern 45.8% of attempts at assisted reproductive technologies excluding artificial inseminations. This proportion is constantly increasing for various reasons. The main objective of this study is to compare the live birth rate following frozen blastocyst transfer (FBT) according to the initial indication for freezing.</div></div><div><h3>Methods</h3><div>This is a retrospective study including patients who underwent FBT between 01/01/2020 and 06/30/2022 at the Regional University Hospital Center of Tours. The results were compared (univariate and multivariate analyses) between the three main indications for freezing: freezing of the complete cohort of blastocysts for risk of ovarian hyperstimulation (=OHS), freezing of supernumerary blastocysts after fresh blastocyst transfer (BT) with pregnancy (=second request) or without pregnancy (=BT failure). Results have also been described for other indications.</div></div><div><h3>Results</h3><div>Among the 963 FBT cycles selected, 28% of live births by thawing were obtained, all indications of freezing combined. A significantly lower rate was identified in the FBT failure group compared to the OHS group. However, after adjustment, the results remained significant for the age of the patient on the freezing cycle but not for the indication for freezing.</div></div><div><h3>Conclusions</h3><div>The outcome of a FBT does not seem significantly impacted by the indication of freezing considering the confounding factors. The prospective analysis of more data from a multicenter study would be necessary to confirm these results.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 12","pages":"Pages 690-696"},"PeriodicalIF":0.6,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"La nouvelle version du site internet du Centre de référence sur les agents tératogènes et ses fonctionnalités optimisées","authors":"Bénédicte Coulm , Delphine Beghin , Mathilde Latour , Bilal Majed , Catherine Vauzelle , Elisabeth Elefant , Benoît Marin","doi":"10.1016/j.gofs.2024.05.005","DOIUrl":"10.1016/j.gofs.2024.05.005","url":null,"abstract":"<div><div>The Centre de Référence sur les Agents Tératogènes (CRAT) is a unique French national reference center involved in the risk assessment of exogenous agents (mainly drugs, but also medical imaging and addictions) on pregnancy, breastfeeding and fertility. To help improve patient care, CRAT makes its expertise available to healthcare professionals via its website (<span><span>www.lecrat.fr</span><svg><path></path></svg></span>), a free, independent and public online resource regularly updated by its multidisciplinary team. In December 2023, a new version was launched, based on the evolutions desired by the CRAT team and on a satisfaction survey of website's users. A predictive search bar integrated into the home page now enables users to find the specific information they are looking for more quickly. To optimize the access via smartphones, a mobile version is now available.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 12","pages":"Pages 725-729"},"PeriodicalIF":0.6,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141285400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Les pièges de l’analyse dichotomique d’une variable biologique continue : l’exemple de la taille maternelle et du pronostic de l’accouchement d’un enfant de plus de 4,0 kg","authors":"Jeremy Boujenah , Anne Wahnich , Diane Korb","doi":"10.1016/j.gofs.2024.01.009","DOIUrl":"10.1016/j.gofs.2024.01.009","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 6","pages":"Pages 425-426"},"PeriodicalIF":0.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139547758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perrine Coste-Mazeau , Magali Hamon , Élodie Ribot , Sébastien Hantz , Sophie Alain
{"title":"Mise en place du dépistage de l’infection congénitale à cytomégalovirus dans une maternité française de type 3","authors":"Perrine Coste-Mazeau , Magali Hamon , Élodie Ribot , Sébastien Hantz , Sophie Alain","doi":"10.1016/j.gofs.2024.01.010","DOIUrl":"10.1016/j.gofs.2024.01.010","url":null,"abstract":"<div><h3>Objectives</h3><p>Congenital cytomegalovirus (CMV) infection is the most common congenital infection and the leading cause of infectious neurosensorial disability in newborns. We wanted to organize the management of women from the beginning of pregnancy allowing access to antenatal treatment with valaciclovir, recognized since 2020 as limiting materno-fetal transmission. To this end, we set up and evaluated the interest of systematic screening for CMV infection in our maternity. We wanted to organize care for women from the very start of pregnancy.</p></div><div><h3>Methods</h3><p>Retrospective and comparative descriptive study carried out at the <em>CHRU de Limoges</em> from July 2017 to December 2019 (targeted screening), then from January 2020 to June 2022, during which period we implemented systematized screening by iterative serologies at the 3rd, 6th, 8th months and before delivery. Our main evaluation criteria were the seroprevalence of CMV infection and the rate of congenital infection. We then described our cases of infection (primary or secondary) during pregnancy.</p></div><div><h3>Results</h3><p>CMV seroprevalence in our pregnant women increased significantly from 52.7% (779/1478 women screened) to 58.4% (3852/6599 women screened) between the 2 study periods (<em>P</em> <!-->=<!--> <!-->0.04). We diagnosed 11 infections during the first part of the study vs. 27 during the second, with a significant increase in primary infections from 0.14% (9/6524 births) to 0.37% (24/6426 births) (<em>P</em> <!-->=<!--> <!-->0.008). Only 3 secondary infections were diagnosed during the second study period. The rate of congenital infections remained stable between the 2 study periods (6 children/6524<!--> <!-->=<!--> <!-->0.09% vs. 8 children/6426<!--> <!-->=<!--> <!-->0.12%; <em>P</em> <!-->=<!--> <!-->0.57).</p></div><div><h3>Conclusion</h3><p>Our results confirmed the interest of screening for CMV infection, while modifying the screening strategy we had initiated.</p></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 6","pages":"Pages 403-409"},"PeriodicalIF":0.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139565258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vaccination contre la varicelle, grossesse et allaitement : un état des lieux","authors":"Catherine Vauzelle , Elisabeth Elefant , Bénédicte Coulm , Mathilde Latour , Delphine Beghin , Benoît Marin","doi":"10.1016/j.gofs.2024.01.012","DOIUrl":"10.1016/j.gofs.2024.01.012","url":null,"abstract":"<div><p>The varicella vaccine is recommended for women with no history of varicella who are planning to become pregnant, as well as for post-pregnancy women, to prevent the occurrence of this illness and its severe complications, especially an embryopathy, when it occurs in a pregnant woman (congenital varicella syndrome). This live attenuated vaccine should not be administered during pregnancy, nor in the month preceding it. However, when this occurs inadvertently, the data collected on the outcomes of exposed pregnancies, although few in women seronegative at the time of vaccination, allow to reassure the patients to date, as no congenital varicella syndrome has been reported to date following accidental vaccination in early pregnancy. On the other hand, during breastfeeding, a woman may be vaccinated if there is an expected short- or medium-term benefit (varicella exposure, planned pregnancy…).</p></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"52 6","pages":"Pages 432-435"},"PeriodicalIF":0.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139681951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}