Journal of Stomatology Oral and Maxillofacial Surgery最新文献

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Radiographic evaluation of nasopalatine canal and its relationship with infraorbital foramen and foramen palatinum majus. 鼻腭管的影像学评价及其与眶下孔和腭大孔的关系。
IF 2.2 3区 医学
Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-07-08 DOI: 10.1016/j.jormas.2025.102492
Kübra Cam, Tuna Sumer, A Zeynep Zengin
{"title":"Radiographic evaluation of nasopalatine canal and its relationship with infraorbital foramen and foramen palatinum majus.","authors":"Kübra Cam, Tuna Sumer, A Zeynep Zengin","doi":"10.1016/j.jormas.2025.102492","DOIUrl":"10.1016/j.jormas.2025.102492","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study is to compare the morphological and dimensional characteristics of the nasopalatine canal (NPC) with those of the infraorbital foramen (IOF) and foramen palatinum majus (FPM) using cone beam computed tomography (CBCT).</p><p><strong>Material and methods: </strong>In CBCT images, the morphological characteristics and dimensional measurements of the three anatomical structures (NPC, bilateral IOF, and FPM) were retrospectively analyzed. In the axial section, the widest diameter of the NPC was measured and categorized based on imaging; normal NPC: (≤6 mm), enlarged NPC (>6 mm and ≤10 mm) and pathology-suspected group, (>10 mm), radiographically suggestive of nasopalatine canal cysts (NPCC). This grouping was purely based on imaging findings and does not equate to a confirmed diagnosis of NPCC, as no histopathological verification was performed.</p><p><strong>Results: </strong>70 patients were included in the normal NPC group, 70 patients in the enlarged NPC group, and 20 patients in the pathology-suspected NPC group. No statistically significant relationship was found between age, sex, and dentition status across the normal, enlarged, and pathology-suspected groups. The vertical diameter of the IOF was significantly higher in the enlarged and pathology-suspected groups. For the FPM, although an increasing tendency was observed bilaterally, statistically significant increases in A-P and M-L diameters were found only on the right side. (p < 0.001).</p><p><strong>Conclusion: </strong>The results indicated that NPC enlargement is associated with increased dimensions of the IOF and FPM. Based on these findings, it can be suggested that individuals with a wider NPC, especially when accompanied by enlarged IOF and FPM, may have a higher radiographic risk profile for NPCC development.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102492"},"PeriodicalIF":2.2,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extensive and delayed necrosis of a free flap following subtotal glossectomy and adjuvant radiotherapy. 舌大部切除及辅助放射治疗后游离皮瓣广泛及迟发性坏死。
IF 2.2 3区 医学
Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-07-08 DOI: 10.1016/j.jormas.2025.102491
Sophie Dugast, Langé Martin, Nadia Benmoussa, Mélanie Doré, Julie Longis, Helios Bertin
{"title":"Extensive and delayed necrosis of a free flap following subtotal glossectomy and adjuvant radiotherapy.","authors":"Sophie Dugast, Langé Martin, Nadia Benmoussa, Mélanie Doré, Julie Longis, Helios Bertin","doi":"10.1016/j.jormas.2025.102491","DOIUrl":"10.1016/j.jormas.2025.102491","url":null,"abstract":"<p><p>Oral tongue squamous cell carcinoma is the most common malignancy of the oral cavity. Treatment of this tumor is based on surgical removal with a centimeter margin, which can be combined with radiotherapy. This case report details a late necrosis of an anterolateral thigh flap used for oncological reconstruction of a subtotal glossectomy requiring comprehensive management. A 61-year-old patient, with no medical history, was treated for a large squamous cell carcinoma with subtotal glossectomy combined with adjuvant radiotherapy. During radiotherapy, radiomucositis appeared on the lateral sides of the flap. The ulcerations continued to progress for several months after the end of treatment, eventually leading to complete necrosis of two-thirds of the flap three months after radiotherapy Our findings suggest that late septic necrosis can develop on severe radiomucositis in patients without significant comorbidities or traditional risk factors. This evolution may also suggest an intrinsic radiosensitivity of the patient.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102491"},"PeriodicalIF":2.2,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stensen' s duct penetration and sialolith formation: a rare complication of thread lifting surgery. 斯坦森导管穿透和帆石形成:提线手术中一种罕见的并发症。
IF 2.2 3区 医学
Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-07-05 DOI: 10.1016/j.jormas.2025.102489
Dan-Ni Zheng, Xiao-Yun Xu, Xiao-Tong Ling, Deng-Gao Liu
{"title":"Stensen' s duct penetration and sialolith formation: a rare complication of thread lifting surgery.","authors":"Dan-Ni Zheng, Xiao-Yun Xu, Xiao-Tong Ling, Deng-Gao Liu","doi":"10.1016/j.jormas.2025.102489","DOIUrl":"10.1016/j.jormas.2025.102489","url":null,"abstract":"<p><p>Sialolithiasis is a relatively frequent occurrence, but the etiology of sialoliths remains unclear. Foreign bodies might enter the salivary duct and induce sialoliths by retrograde migration or penetrating trauma. Several reports have involved salivary duct stones formed around a foreign body, such as fishbone, vegetable seed, grass blade, et al. However, an iatrogenic foreign body-induced sialolith is scarcely reported. Thread lifting is a minimally invasive technique for facial rejuvenation with the advantages of short recovery, good-lifting and high satisfaction rate. The injury of the Stensen's duct was scarcely found in the complications of thread lifting. This paper reports three cases of sialoliths formed by the thread penetrating the Stensen's duct after facial thread lifting. These cases were treated successfully under endoscopy, though the lifting thread was not extracted in one case. The etiology of sialoliths is reviewed, and the complications of thread lifting are discussed.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102489"},"PeriodicalIF":2.2,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of photobiomodulation on rat parotid gland cells after ionizing radiation - an experimental study in animal model - Part 1. 电离辐射后光生物调节对大鼠腮腺细胞的影响-动物模型的实验研究-第一部分。
IF 2.2 3区 医学
Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-07-03 DOI: 10.1016/j.jormas.2025.102485
Cristina Paixão Durães, Larissa Lopes Fonseca, Sérgio Henrique Sousa Santos, Arlen de Paulo Santiago Filho, Marise Fagundes Silveira, Lorena Dos Reis Pereira Queiroz, Allysson Steve Mota Lacerda, Alfredo Maurício Batista de Paula, Lucyana Conceição Farias, André Luiz Sena Guimarães
{"title":"Effect of photobiomodulation on rat parotid gland cells after ionizing radiation - an experimental study in animal model - Part 1.","authors":"Cristina Paixão Durães, Larissa Lopes Fonseca, Sérgio Henrique Sousa Santos, Arlen de Paulo Santiago Filho, Marise Fagundes Silveira, Lorena Dos Reis Pereira Queiroz, Allysson Steve Mota Lacerda, Alfredo Maurício Batista de Paula, Lucyana Conceição Farias, André Luiz Sena Guimarães","doi":"10.1016/j.jormas.2025.102485","DOIUrl":"10.1016/j.jormas.2025.102485","url":null,"abstract":"<p><strong>Background: </strong>Radiotherapy for head and neck cancers often impairs salivary gland function. Photobiomodulation (PBM) has emerged as a potential intervention to mitigate radiation-induced tissue damage. This study aimed to evaluate the effects of PBM on the parotid glands of Wistar rats subjected to ionizing radiation.</p><p><strong>Methods: </strong>Forty-two male Wistar rats (7-8 weeks old) were randomly assigned to seven groups (n = 6). G1: control; G2: radiotherapy only (20 Gy); G3: PBM only; G4-G7: PBM combined with radiotherapy. PBM was applied using the Laser Duo (MMOptics®) with 660 nm and/or 808 nm wavelengths, varying in dose and number of application points. The histological analysis focused on preserving the acinar area. Receiver operating characteristic (ROC) curve analysis was used to determine the threshold for preserved acinar architecture.</p><p><strong>Results: </strong>The group receiving combined PBM (660 nm + 808 nm, 54 J per gland; G5) demonstrated the highest preservation of acinar morphology, closely resembling the control. Groups receiving isolated red or infrared wavelengths (G4, G6) showed moderate protection. The lowest dose group (G7, 1.8 J) was ineffective.</p><p><strong>Conclusion: </strong>PBM significantly reduced RT-induced damage to the parotid glands in a dose-dependent manner. The red laser protocol at 27 J per gland showed the highest level of tissue preservation. These findings support the potential of PBM as a protective adjunct during radiation therapy (RT) and justify further studies to standardize optimal clinical parameters.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102485"},"PeriodicalIF":2.2,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144565469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphometric assessment of greater palatine canal and foramen variations in cleft lip and palate patients using CBCT. 用CBCT评价唇腭裂患者腭大管及腭孔的形态变化。
IF 2.2 3区 医学
Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-07-03 DOI: 10.1016/j.jormas.2025.102487
Rabia Duman Tepe, Beliz Guray, Sukriye Neslihan Senel, Hulya Cakir Karabas
{"title":"Morphometric assessment of greater palatine canal and foramen variations in cleft lip and palate patients using CBCT.","authors":"Rabia Duman Tepe, Beliz Guray, Sukriye Neslihan Senel, Hulya Cakir Karabas","doi":"10.1016/j.jormas.2025.102487","DOIUrl":"10.1016/j.jormas.2025.102487","url":null,"abstract":"<p><strong>Objectives: </strong>Anatomical variation of the greater palatine canal (GPC) is critical for safe regional anesthesia and posterior maxillary surgery. This study aimed to evaluate GPC anatomy in cleft lip and palate (CLP) patients using cone-beam computed tomography (CBCT) to support safer clinical interventions.</p><p><strong>Methods: </strong>Anatomical comparisons were performed between CLP patients and non-cleft controls using CBCT scans. Evaluated parameters included greater palatine foramen (GPF) width, linear distances from the GPF to surrounding anatomical landmarks (such as the pterygoid canal (PC), infraorbital foramen (IOF), occlusal plane, and midsagittal plane), angular measurements of the GPC (transverse and vertical angles, and the angle toward the pterygopalatine fossa), the number of lesser palatine foramina, and the position of the GPF relative to maxillary molars. Subgroup analyses were conducted within the CLP group based on cleft type (unilateral cleft side, non-cleft side, bilateral), age (≤16 vs. >16 years), and sex.</p><p><strong>Results: </strong>The study included 118 patients with CLP and 118 healthy controls. CLP patients demonstrated significantly longer PC-IOF distances and significantly shorter GPF-PC distances compared to controls (P < 0.001 for both). In addition, both transverse and vertical GPC angles were significantly greater in the CLP group (P < 0.001). Subgroup analysis revealed that bilateral CLP patients had lower PC-IOF distances and smaller vertical GPC angles compared to those with unilateral clefts (p = 0.018, p = 0.011).</p><p><strong>Conclusions: </strong>CLP patients demonstrate anatomical variations in GPC morphology that may affect anesthetic access and surgical safety. These findings highlight the value of individualized CBCT-based planning in maxillary procedures.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102487"},"PeriodicalIF":2.2,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral inferiorly based nasolabial flaps for full-thickness reconstruction of large lower lip defects following tumour resection. 双侧下基底鼻唇瓣在肿瘤切除后大面积下唇缺损全层重建中的应用。
IF 2.2 3区 医学
Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-07-03 DOI: 10.1016/j.jormas.2025.102488
Mansour Elmoatasembellah, Omar Hamdy, Mohammad Attia, Ibrahim Nazif, Shadi Awny
{"title":"Bilateral inferiorly based nasolabial flaps for full-thickness reconstruction of large lower lip defects following tumour resection.","authors":"Mansour Elmoatasembellah, Omar Hamdy, Mohammad Attia, Ibrahim Nazif, Shadi Awny","doi":"10.1016/j.jormas.2025.102488","DOIUrl":"10.1016/j.jormas.2025.102488","url":null,"abstract":"<p><strong>Objective: </strong>To report on the feasibility and outcomes of using inferiorly based nasolabial flaps for the reconstruction of large lower lip defects following tumour resection.</p><p><strong>Methods: </strong>Using a retrospective cohort study design, we enrolled a cohort of patients with large lower lip squamous cell carcinoma who underwent ablative tumour resection and full-thickness reconstruction with bilateral nasolabial flaps at Mansoura University Oncology Centre and Mansoura Health Insurance Hospital between June 2023 and August 2024. The predictor variables were categorized as preoperative, operative, or postoperative variables. The outcomes of interest were oral competence, wound dehiscence, flap necrosis, reoperation, and tumour recurrence. Appropriate statistics were computed using a cut-off value of 0.05.</p><p><strong>Results: </strong>The study included six patients with a mean age of 62.5 ± 10.3 years and a mean body mass index (BMI) of 29.93 ± 1.7 kg/m<sup>2</sup>. The average tumour size was 4.7 ± 0.8 cm. All patients were male smokers who smoked more than twenty cigarettes per day. Two operations were complicated with partial flap necrosis (33.3 %), and three patients (50 %) experienced minimal drooling, which improved over time. Only BMI and tumor grade showed a significant relationship with the incidence of postoperative complications (P = 0.009, 0.006, respectively). A good aesthetic outcome was observed in all cases.</p><p><strong>Conclusion: </strong>Based on this small cohort, the bilateral inferiorly based nasolabial flap technique is a safe and easily harvested option that provides acceptable functional and cosmetic outcomes, with minimal donor site morbidity, for the reconstruction of large lower lip defects following tumour resection. It could be an alternative to other longer or more aggressive treatment methods, such as microsurgery, for elderly patients or those with medical comorbidities.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102488"},"PeriodicalIF":2.2,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haploinsufficiency of SF3B2 revealed by a craniofacial microsomia with atypical presentation: a case report. 不典型表现的颅面小畸形显示SF3B2单倍不足1例。
IF 2.2 3区 医学
Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-07-03 DOI: 10.1016/j.jormas.2025.102486
Antoine Octau, Cindy Colson, Joel Ferri
{"title":"Haploinsufficiency of SF3B2 revealed by a craniofacial microsomia with atypical presentation: a case report.","authors":"Antoine Octau, Cindy Colson, Joel Ferri","doi":"10.1016/j.jormas.2025.102486","DOIUrl":"10.1016/j.jormas.2025.102486","url":null,"abstract":"<p><p>Otomandibular syndrome is primarily characterised by craniofacial microsomia (CFM). Pathogenic loss-of-function variants of the SF3B2 gene, which encodes the U2 subunit of the spliceosome, can cause CFM through a haploinsufficiency mechanism. This study aims to present the clinical phenotype and maxillofacial management of a patient carrying a novel SF3B2 gene variant. We present the case of a patient with a heterozygous de novo pathogenic variant of the SF3B2 gene who presented with an otomandibular syndrome accompanied by progressive camptodactyly of the extremities, which had not been described previously. Particularly low maxillary and mandibular bone density was observed during bimaxillary osteotomy, necessitating adaptation of the surgical protocol. This case expands the phenotypic spectrum of anomalies associated with the SF3B2 gene by indicating potential subclinical acral and bone involvement. It also emphasises the importance of genetic analysis in complex craniofacial malformations.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102486"},"PeriodicalIF":2.2,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144565470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stress distribution in implant-supported conometric single crown restorations: A finite element analysis. 种植体支持单冠修复体的应力分布:有限元分析。
IF 2.2 3区 医学
Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-07-02 DOI: 10.1016/j.jormas.2025.102484
Sinem Vural, Buket Evren, Coşkun Yıldız
{"title":"Stress distribution in implant-supported conometric single crown restorations: A finite element analysis.","authors":"Sinem Vural, Buket Evren, Coşkun Yıldız","doi":"10.1016/j.jormas.2025.102484","DOIUrl":"10.1016/j.jormas.2025.102484","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the present study was to evaluate the effect of connection, restorative material type, and loading forces on the stress distribution in implant-supported conometric single crown restorations using a three-dimensional finite element analysis method.</p><p><strong>Methods: </strong>Restorations are produced using two different all-ceramic materials used in maxillary right premolar conometric abutments and caps (Conometeric abutment EV, Conometeric Final Cap, Dentsply Implants, Sweden) on implants with three different types of connection: morse taper connection (MTC) (Ankylos, Dentsply Implants, Sweden), conical connection (CC) (Astra-Tech OsseoSpeed EV, Dentsply Implants, Sweden), and internal flat connection (IFC) (Xive, Dentsply, Sweden). Three-dimensional finite element analysis was used to evaluate the amount and distribution of stress around implants under different vertical and oblique loading conditions.</p><p><strong>Results: </strong>The maximum stress distribution in the implant abutment contact area in the IFC was 565.44 MPa and screw peak stress values were determined to be 518.96 MPa in the transition zone for MTC. MTC caused the lowest bone stress, although there was no significant difference between the connection systems in terms of material type. The LDS material exhibited the greatest stress on the conometric cap for IFC (447.52 MPa) under oblique loading conditions.</p><p><strong>Conclusion: </strong>Stress on the bone surface and implant abutment contact was higher in the IFC group. IFC has a disadvantage in term of increases the possibility of bone destruction.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102484"},"PeriodicalIF":2.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144565471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-linked hyaluronic acid enriched with amino acids used for bone filler defect: a histological and histomorphometry study in rabbit tibiae. 富含氨基酸的交联透明质酸用于骨填充物缺损:兔胫骨的组织学和组织形态学研究。
IF 2.2 3区 医学
Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-06-30 DOI: 10.1016/j.jormas.2025.102435
Antonio Scarano, Erda Qorri, Sergio Alexandre Gehrke, Gianluca Nicolai, Sergio Rexhep Tari
{"title":"Cross-linked hyaluronic acid enriched with amino acids used for bone filler defect: a histological and histomorphometry study in rabbit tibiae.","authors":"Antonio Scarano, Erda Qorri, Sergio Alexandre Gehrke, Gianluca Nicolai, Sergio Rexhep Tari","doi":"10.1016/j.jormas.2025.102435","DOIUrl":"10.1016/j.jormas.2025.102435","url":null,"abstract":"<p><strong>Background: </strong>Today we have numerous bone substitutes with different chemical and physical properties and with different sizes, quantities and porosity. The biomaterials are available in particles, gel, blocks, and cement pastes. The aim of this study is to evaluate the influence of hyaluronic acid gel enriched with amino acids on bone healing in a rabbit artificial bone defect.</p><p><strong>Methods: </strong>Six rabbits were used in this study, for each tibia, a 3 mm bilateral non critical-size circular defect was produced. The drilling was performed on cortical bone with no invasion of the medullary component. The bone defect was filled with Hyaluronic acid enriched with amino acid while the second defect was used as empty control. The HA filling enriched with amino acid was positioned into the bone defect with no pushing into the medullary space. No covering membranes were applied on top of the bone defect. The rabbits were euthanized by an intravenous pentobarbital overdose after 4 weeks and a total of 36 biopsies (6 for each group) were retrieved. The samples were processed to obtain histological sections.</p><p><strong>Results: </strong>In the control sites, newly formed tissues in the defects were characterized by 25 ± 3 % of lamellar bone, 25 ± 1 % of woven bone and 50 ± 3 % of medullary spaces. The osteoblast count in the bone defect was 15±3 and 1 ± 2 vessel. In the test sites the morphometry findings were characterized by 28 ± 3 % of lamellar bone, 73 ± 1 % of woven bone and 0 % of marrow spaces. The osteoblast and vessel count was 87±3 and 6 ± 2 vessels per field. Statistical differences were found for the number of osteoblasts, vessels and new bone. (p < 0.05).</p><p><strong>Conclusions: </strong>The efficacy of the present investigation revealed that HA increases the new vessel and bone formation and induces a more rapid healing in rabbit bone defects if compared to the control.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102435"},"PeriodicalIF":2.2,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vascularized iliac crest flap with double musculocutaneous skin islands for reconstruction of composite buccal and mandibular defects after gingival squamous cell carcinoma resection: A case report. 带血管的髂嵴瓣联合双肌皮岛修复龈鳞癌术后颊、下颌复合缺损1例。
IF 2.2 3区 医学
Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-06-29 DOI: 10.1016/j.jormas.2025.102483
Bang Zeng, Hao Lin, Diarra Drissa, Renbin Zhou, Lei Ma, Xinyi Zhao, Jialiang Chen, Tianfu Wu, Bing Liu
{"title":"Vascularized iliac crest flap with double musculocutaneous skin islands for reconstruction of composite buccal and mandibular defects after gingival squamous cell carcinoma resection: A case report.","authors":"Bang Zeng, Hao Lin, Diarra Drissa, Renbin Zhou, Lei Ma, Xinyi Zhao, Jialiang Chen, Tianfu Wu, Bing Liu","doi":"10.1016/j.jormas.2025.102483","DOIUrl":"10.1016/j.jormas.2025.102483","url":null,"abstract":"<p><p>Mandibular gingival squamous cell carcinoma (GSCC) is a challenging malignancy often requiring extensive surgical resection and complex reconstruction. This study presents a 69-year-old male with left mandibular GSCC, treated with segmental mandibulectomy and selective neck dissection, followed by reconstruction using a deep circumflex iliac artery (DCIA) vascularized iliac crest flap with double musculocutaneous skin islands. Preoperative virtual surgical planning and 3D-printed surgical guides facilitated precise osteotomy and optimal flap design. The harvested iliac flap provided robust vascularization, adequate bone volume for mandibular continuity, and dual skin paddles for intraoral and extraoral soft tissue coverage. Postoperative evaluation demonstrated excellent functional and aesthetic outcomes, with stable osseous integration, viable soft tissue reconstruction, and no recurrence. This case underscores the versatility of the DCIA iliac crest flap in restoring both mandibular structure and oral function, highlighting advancements in microvascular surgery, 3D planning, and patient-specific reconstruction strategies. This case highlights the potential of the DCIA flap in addressing complex maxillofacial defects. However, it is critical to note that these findings are exclusively derived from a single-case analysis. Therefore, a larger cohort study is needed in future research to validate its applicability in practical scenarios.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102483"},"PeriodicalIF":2.2,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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