Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology最新文献_第3页

Regulation of energy metabolism by non-coding RNAs in livestock species: a review. 非编码rna对家畜能量代谢的调控研究进展

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2025-02-01 Epub Date: 2024-12-06 DOI: 10.1007/s00360-024-01596-8

Faiz-Ul Hassan, Muhammad Safdar, Muhammad Younus, Muhammad Asif Arain

{"title":"Regulation of energy metabolism by non-coding RNAs in livestock species: a review.","authors":"Faiz-Ul Hassan, Muhammad Safdar, Muhammad Younus, Muhammad Asif Arain","doi":"10.1007/s00360-024-01596-8","DOIUrl":"10.1007/s00360-024-01596-8","url":null,"abstract":"The optimisation of livestock production relies on efficient energy metabolism. This review focused on elaborate regulatory processes governed by non-coding RNAs (ncRNAs), such as microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs). It explores the complex energy metabolism processes in livestock, elucidating the functions of ncRNAs in the expression of genes and pathways. miRNAs have been identified as significant regulators of glycolysis and glucose metabolism, whereas lncRNAs are known to affect adipogenesis and mitochondrial activity. Moreover, circRNAs have a substantial influence on the regulation of energy. In addition, this is not only enriching non-coding RNA-mediated energy control but also sheds light on possible applications. It is derived from its ability to condense complex molecular systems, thereby offering crucial insights to researchers. Through a comprehensive analysis of the intricate relationship between ncRNAs and energy metabolism, the information of this review provides a valuable framework for the implementation of focused interventions that hold the potential to significantly enhance the efficiency of livestock production.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"1-12"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of elevated incubation temperatures on learning and brain anatomy of hatchling and juvenile lizards. 升高孵化温度对幼蜥和幼蜥学习和脑解剖的影响。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2025-02-01 Epub Date: 2024-12-08 DOI: 10.1007/s00360-024-01595-9

Iván Beltrán, Catarina Vila-Pouca, Rebecca Loiseleur, Jonathan K Webb, Suzana Herculano-Houzel, Martin J Whiting

{"title":"Effect of elevated incubation temperatures on learning and brain anatomy of hatchling and juvenile lizards.","authors":"Iván Beltrán, Catarina Vila-Pouca, Rebecca Loiseleur, Jonathan K Webb, Suzana Herculano-Houzel, Martin J Whiting","doi":"10.1007/s00360-024-01595-9","DOIUrl":"10.1007/s00360-024-01595-9","url":null,"abstract":"Global warming is a major threat to reptiles because temperature strongly affects their development. High incubation temperatures reduce hatchling body size and physiological performance; however, its effects on brain development and learning abilities are less well understood. In particular, it remains unclear if the effects of elevated temperatures on learning are restricted to hatchlings or instead will persist later in life. To address this gap, we examined the effect of 'current' and 'future' (end-of-century, + 4 °C) incubation temperatures on hatchling and juvenile geckos Amalosia lesueurii, to test: (1) if elevated temperatures affect hatchling learning ability; (2) if the effects on learning persist in juvenile lizards, and (3) if and how elevated temperatures affect hatchling and juvenile brain anatomy and neuronal count. We found that fewer future-incubated hatchlings succeeded in the learning tasks. Nonetheless, the successful ones needed fewer trials to learn compared to current-incubated hatchlings, possibly due to a higher motivation. Reduced learning ability was still observed at the juvenile stage, but it did not differ between treatments due to a reduced cognitive performance of current-incubated juveniles. Future-incubated hatchlings had a smaller telencephalon, but this pattern was not found in juveniles. Neuron number and density in hatchlings or juveniles from both treatments were not different. Our results suggest that global warming will affect hatchling survival in the wild but it remains unclear if future-incubated lizards could compensate for the harmful effects of elevated temperatures. Further testing beyond the laboratory is required to understand whether phenotypic plasticity in lizards is sufficient to track global warming.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"67-79"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic differentiation of brushtail possum populations resistant and susceptible to plant toxins revealed via differential gene expression. 通过基因表达差异揭示对植物毒素有抵抗力和易感性的刷尾负鼠种群的代谢分化。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2025-02-01 Epub Date: 2024-11-04 DOI: 10.1007/s00360-024-01591-z

David Carmelet-Rescan, Mary Morgan-Richards, Steven A Trewick

{"title":"Metabolic differentiation of brushtail possum populations resistant and susceptible to plant toxins revealed via differential gene expression.","authors":"David Carmelet-Rescan, Mary Morgan-Richards, Steven A Trewick","doi":"10.1007/s00360-024-01591-z","DOIUrl":"10.1007/s00360-024-01591-z","url":null,"abstract":"The Australian brushtail possum (Trichosurus vulpecula) is adapted to a wide range of food plants across its range and is exposed to numerous physiological challenges. Populations that are resistant to the plant toxin sodium fluoroacetate are of particular interest as this compound has been used since the 1940s for vertebrate pest management around the world. Candidate gene identification is an important first step in understanding how spatial populations have responded to local selection resulting in local physiological divergence. We employ differential gene expression of liver samples from wild-caught brushtail possums from toxin-resistant and toxin-susceptible populations to identify candidate genes that might be involved in metabolic pathways associated with toxin-resistance. This allowed us to identify genetic pathways involved in resistance to the plant toxin sodium fluoroacetate in Western Australian possums but not those originally from south eastern Australia. We identified differentially expressed genes in the liver that are associated with cell signalling, encapsulating structure, cell mobility, and tricarboxylic acid cycle. The gene expression differences detected indicate which metabolic pathways are most likely to be associated with sodium fluoroacetate resistance in these marsupials and we provide a comprehensive list of candidate genes and pathways to focus on for future studies.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"103-121"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Entropy generation and water conservation in the mammalian nephron. 哺乳动物肾元的熵产和水分保存。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2025-02-01 Epub Date: 2025-01-03 DOI: 10.1007/s00360-024-01599-5

Pedro Goes Nogueira-de-Sá, José Eduardo Pereira Wilken Bicudo, José Guilherme Chaui-Berlinck

{"title":"Entropy generation and water conservation in the mammalian nephron.","authors":"Pedro Goes Nogueira-de-Sá, José Eduardo Pereira Wilken Bicudo, José Guilherme Chaui-Berlinck","doi":"10.1007/s00360-024-01599-5","DOIUrl":"10.1007/s00360-024-01599-5","url":null,"abstract":"During the transition from fresh waters to terrestrial habitats, significant adaptive changes occurred in kidney function of vertebrates to cope with varying osmotic challenges. We investigated the mechanisms driving water conservation in the mammalian nephron, focusing on the relative contributions of active ion transport and Starling forces. We constructed a thermodynamic model to estimate the entropy generation associated with different processes within the nephron, and analyzed their relative importance in urine formation. We demonstrate that active ionic reabsorption exerts a pressure above 15,000 torr, a value more than 500 times greater than Starling forces. The entropy generation of the reabsorption process is found to be 20-fold higher than that of renal blood perfusion. These findings imply that the evolutionary history of vertebrates, particularly terrestrial mammals, has shaped the renal architecture to prioritize water conservation by means of an entropically costly process. This approach to the nephron function provides insights into the physiological adaptations of terrestrial vertebrates to conserve water and sheds light on the intricate interplay between environmental conditions and evolutionary responses in renal physiology.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"81-89"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differential fatty acids utilization across life stages in a Vespa species. 一种 Vespa 物种在不同生命阶段对脂肪酸的利用存在差异。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2025-02-01 Epub Date: 2024-10-10 DOI: 10.1007/s00360-024-01589-7

Sofia Bouchebti, Eran Levin

{"title":"Differential fatty acids utilization across life stages in a Vespa species.","authors":"Sofia Bouchebti, Eran Levin","doi":"10.1007/s00360-024-01589-7","DOIUrl":"10.1007/s00360-024-01589-7","url":null,"abstract":"Dietary fatty acids (FAs) are essential macronutrients affecting animal fitness, growth, and development. While the degree of saturation of FAs usually determines the level of absorption and allocation within the body, the utilization of dietary FAs across the life stages of individuals remains unknown. We used three different 13 C labeled FAs, with a different saturation level (linoleic acid (18:2), oleic acid (18:1), and palmitic acid (16:0)), to investigate the absorption and allocation of dietary FAs across the life stages of the Oriental hornet. Our results show that only larvae utilized all tested FAs as metabolic fuel, with palmitic acid being oxidized at the highest rate. Oleic and palmitic acids were predominantly incorporated into larval tissues, while oleic acid dominated pupal tissues. In contrast, linoleic and oleic acids were predominantly incorporated into adult tissues. These findings highlight a life stage-dependent shift in certain FAs utilization, with palmitic acid mostly utilized in early stages and linoleic acid in adulthood, while oleic acid remained consistently utilized across all life stages. This study emphasizes the importance of considering FA saturation and life stage dynamics in understanding FA utilization patterns.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"23-29"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterisation of intestinal amino acid and oleic acid absorption and their interaction in the Pacific spiny dogfish (Squalus suckleyi). 太平洋角鲨肠道氨基酸和油酸吸收特征及其相互作用。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2025-02-01 Epub Date: 2025-01-16 DOI: 10.1007/s00360-024-01601-0

Alyssa M Weinrauch, Tamzin A Blewett, W Gary Anderson

{"title":"Characterisation of intestinal amino acid and oleic acid absorption and their interaction in the Pacific spiny dogfish (Squalus suckleyi).","authors":"Alyssa M Weinrauch, Tamzin A Blewett, W Gary Anderson","doi":"10.1007/s00360-024-01601-0","DOIUrl":"10.1007/s00360-024-01601-0","url":null,"abstract":"Elasmobranchs are commonly carnivores and are important in energy transfer across marine ecosystems. Despite this, relatively few studies have examined the physiological underpinnings of nutrient acquisition in these animals. Here, we investigated the mechanisms of uptake at the spiral valve intestine for two representative amino acids (L-alanine, L-leucine) and one representative fatty acid (oleic acid), each common to the diet of a carnivore, the Pacific spiny dogfish (Squalus suckleyi). Transport was saturable for all three nutrients, depending upon transport calculation metric (i.e., mucosal disappearance, serosal appearance, or tissue accumulation). Over 0-10 mM range of amino acids the concentration at which ½ maximal transport occurred (Km; a measure of transporter affinity) was 11.9 and 11.2 mM for tissue accumulation of alanine and leucine, respectively. Oleic acid transport was measured at lower concentrations (0-200 µM) and tissue accumulation did not reach saturation. Putative amino acid transport systems were delineated upon confirmation of sodium dependence and competitive inhibition with threonine, glycine, and lysine. The interplay of nutrient combinations on the modulation of nutrient acquisition rates, which better mimics the complex composition of both a meal and the internal osmolytes, was next investigated. Here, the application of serosal oleic acid led to diminished mucosal disappearance of leucine. Feeding did not significantly alter transport rates, perhaps indicative of maximal transport of these energy sources whenever the substrate is available given their importance both as metabolic fuels and precursors to the osmolyte urea.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"53-65"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Apneic uptake of atmospheric O₂ by deeply hypothermic nestlings of the white-footed mouse (Peromyscus leucopus): circulation and lungs. 体温极低的白足鼠雏鼠对大气中氧气的窒息性吸收：循环和肺部。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2025-02-01 Epub Date: 2024-10-08 DOI: 10.1007/s00360-024-01585-x

Richard W Hill, Jacob J Manteuffel, Bradley A White

{"title":"Apneic uptake of atmospheric O2 by deeply hypothermic nestlings of the white-footed mouse (Peromyscus leucopus): circulation and lungs.","authors":"Richard W Hill, Jacob J Manteuffel, Bradley A White","doi":"10.1007/s00360-024-01585-x","DOIUrl":"10.1007/s00360-024-01585-x","url":null,"abstract":"Nestling white-footed mice (Peromyscus leucopus) are born in the earliest days of spring in cold climates. If the nestlings are by accident exposed to ambient temperatures near freezing (0-7 °C) at early ages (2-10 days old), they may experience body temperatures (Tbs) equally low. During such hypothermia, although their heart keeps beating, they become apneic (cease inhaling and exhaling). However, they have an exceptional ability (e.g., compared to Mus musculus) to tolerate these conditions for at least several hours, after which they revive if rewarmed by parents. This paper addresses the physiology of the apneic period. We show that apneic, hypothermic nestlings undergo physiologically important exchanges of gases with the atmosphere. These gas exchanges do not occur across the skin. Instead they occur via the trachea and lungs even though the animals are apneic. Most significantly, when hypothermic neonates are in apnea in ordinary air, they take up O2 steadily from the atmosphere throughout the apneic period, and the evidence available indicates that this O2 uptake is essential for the nestlings' survival. At Tbs of 2-7 °C, the nestlings' rate of O2 consumption varies quasi-exponentially with Tb and averages 0.04 mL O2 g- 1 h- 1, closely similar to the rate expressed by adult mammalian hibernators in hibernation at similar Tbs. Morphometric analysis indicates that, at all focal ages, O2 transport along the full length of the trachea can take place by diffusion at rates adequate to meet the measured rates of metabolic O2 consumption.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"123-139"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Whether hypoxia tolerance improved after short-term fasting is closely related to phylogeny but not to foraging mode in freshwater fish species. 淡水鱼类短期禁食后耐缺氧能力是否提高与系统发育密切相关，但与觅食模式无关。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-12-01 Epub Date: 2024-09-30 DOI: 10.1007/s00360-024-01588-8

Ke-Ren Huang, Qian-Ying Liu, Yong-Fei Zhang, Yu-Lian Luo, Cheng Fu, Xu Pang, Shi-Jian Fu

{"title":"Whether hypoxia tolerance improved after short-term fasting is closely related to phylogeny but not to foraging mode in freshwater fish species.","authors":"Ke-Ren Huang, Qian-Ying Liu, Yong-Fei Zhang, Yu-Lian Luo, Cheng Fu, Xu Pang, Shi-Jian Fu","doi":"10.1007/s00360-024-01588-8","DOIUrl":"10.1007/s00360-024-01588-8","url":null,"abstract":"The combined stresses of fasting and hypoxia are common events during the life history of freshwater fish species. Hypoxia tolerance is vital for survival in aquatic environments, which requires organisms to down-regulate their maintenance energetic expenditure while simultaneously preserving physiological features such as oxygen supply capacity under conditions of food deprivation. Generally, infrequent-feeding species who commonly experience food shortages might evolve more adaptive strategies to cope with food deprivation than frequent-feeding species. Thus, the present study aimed to test whether the response of hypoxia tolerance in fish to short-term fasting (2 weeks) varied with different foraging modes. Fasting resulted in similar decreases in maintenance energetic expenditure and similar decreases in Pcrit and Ploe between fishes with different foraging modes, whereas it resulted in decreased oxygen supply capacity only in frequent-feeding fishes. Furthermore, independent of foraging mode, fasting decreased Pcrit and Ploe in all Cypriniformes and Siluriformes species but not in Perciformes species. The mechanism for decreased Pcrit and Ploe in Cypriniformes and Siluriformes species is at least partially due to the downregulated metabolic demand and/or the maintenance of a high oxygen supply capacity while fasting. The present study found that the effect of fasting on hypoxia tolerance depends upon phylogeny in freshwater fish species. The information acquired in the present study is highly valuable in aquaculture industries and can be used for species conservation in the field.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"843-853"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic effects of physical exercise on zebrafish (Danio rerio) fed a high-fat diet. 体育锻炼对喂食高脂肪食物的斑马鱼（Danio rerio）的代谢影响。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-12-01 Epub Date: 2024-07-31 DOI: 10.1007/s00360-024-01577-x

Moises Silvestre de Azevedo Martins, William Franco Carneiro, Kianne Silva Monteiro, Stefania Priscilla de Souza, André Rodrigues da Cunha Barreto Vianna, Luis David Solis Murgas

{"title":"Metabolic effects of physical exercise on zebrafish (Danio rerio) fed a high-fat diet.","authors":"Moises Silvestre de Azevedo Martins, William Franco Carneiro, Kianne Silva Monteiro, Stefania Priscilla de Souza, André Rodrigues da Cunha Barreto Vianna, Luis David Solis Murgas","doi":"10.1007/s00360-024-01577-x","DOIUrl":"10.1007/s00360-024-01577-x","url":null,"abstract":"The present study aimed to establish zebrafish as an experimental model for investigations into obesity and physical exercise, as well as to assess the effects of these factors on metabolism. The experiment spanned twelve weeks, comprising a feeding trial during which the last four weeks incorporated a physical exercise protocol. This protocol involved placing fifteen animals in a five-liter aquarium, where they were subjected to swimming at an approximate speed of 0.08 m/s for 30 min daily. Throughout the experiment, histological analyses of visceral, subcutaneous, and hepatic adipose tissues were conducted, along with biochemical analyses of total cholesterol and its fractions, triglycerides, glucose, lactate, and alanine aminotransferase (ALT) levels. Additionally, oxidative stress markers, such as reactive oxygen species (ROS) levels, superoxide dismutase (SOD) activity, and catalase activity and the formation of thiobarbituric acid-reactive substances, were investigated. The results revealed that the group fed a high-fat diet exhibited an increase in ROS production and SOD activity. In contrast, the group administered the high-fat diet and subjected to physical exercise demonstrated a notable reduction in visceral adipocyte area, hepatic steatosis levels, ALT levels, and SOD activity. These findings indicate that physical exercise has a positive effect on obesity and oxidative stress in zebrafish, providing promising evidence for future investigations in this field.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"793-804"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic rate and saliva cortisol concentrations in socially housed adolescent guinea pigs. 社会饲养的青少年豚鼠的代谢率和唾液皮质醇浓度。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-12-01 Epub Date: 2024-07-17 DOI: 10.1007/s00360-024-01576-y

Matthias Nemeth, Susanna Fritscher, Klara Füreder, Bernard Wallner, Eva Millesi

{"title":"Metabolic rate and saliva cortisol concentrations in socially housed adolescent guinea pigs.","authors":"Matthias Nemeth, Susanna Fritscher, Klara Füreder, Bernard Wallner, Eva Millesi","doi":"10.1007/s00360-024-01576-y","DOIUrl":"10.1007/s00360-024-01576-y","url":null,"abstract":"An individual's energetic demands and hence metabolic rate can strongly change during adolescence, a phase characterized by profound morphological, physiological, and endocrine changes. Glucocorticoid hormones (e.g. cortisol) are released in response to hypothalamic-pituitary-adrenal-axis activity, modulate several metabolic processes, and can also be linked to increased metabolic rate. In domestic guinea pigs (Cavia aperea f. porcellus) housed in same-sex groups, cortisol concentrations increase during adolescence in males but remain stable in females, which was suggested to be related to different energetic demands by age. We therefore measured metabolic rate through oxygen (O2) consumption over 2.5 h in male and female guinea pigs housed in same-sex groups during adolescence at ages of 60, 120, and 180 days, which was paralleled by analyses of saliva cortisol concentrations before and after the measurement. The statistical analyses involved whole body metabolic rate (ml O2/h), body mass-corrected metabolic rate (ml O2/h/kg), and body mass-independent metabolic rate (ml O2/h statistically corrected for body mass). We found increasing cortisol concentrations with age in males only, but none of the three metabolic rate analyses revealed a sex difference by age. On the individual level, repeatability across ages was found in metabolic rate as well as in body mass and cortisol concentrations after the measurement, but not in \"basal\" cortisol concentrations. Our results suggest no sex-specific changes in metabolic rate and hence equal energetic demands in male and female guinea pigs during adolescence. Moreover, metabolic rate clearly represents a highly stable physiological trait already early in a guinea pig's life irrespective of rather fluctuating cortisol concentrations.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"925-933"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11511739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141629379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0