Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology最新文献_第4页

Cellular mechanisms of ion and acid-base regulation in teleost gill ionocytes. 鱼鳃离子细胞的离子和酸碱调节细胞机制

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-10-01 Epub Date: 2024-05-18 DOI: 10.1007/s00360-024-01560-6

Anthony Kovac, Greg G Goss

引用次数: 0

Fish gill chemosensing: knowledge gaps and inconsistencies. 鱼鳃化学传感：知识差距和不一致。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-10-01 Epub Date: 2024-05-17 DOI: 10.1007/s00360-024-01553-5

Erin M Leonard, Cosima S Porteus, Deidre Brink, William K Milsom

{"title":"Fish gill chemosensing: knowledge gaps and inconsistencies.","authors":"Erin M Leonard, Cosima S Porteus, Deidre Brink, William K Milsom","doi":"10.1007/s00360-024-01553-5","DOIUrl":"10.1007/s00360-024-01553-5","url":null,"abstract":"In this review, we explore the inconsistencies in the data and gaps in our knowledge that exist in what is currently known regarding gill chemosensors which drive the cardiorespiratory reflexes in fish. Although putative serotonergic neuroepithelial cells (NEC) dominate the literature, it is clear that other neurotransmitters are involved (adrenaline, noradrenaline, acetylcholine, purines, and dopamine). And although we assume that these agents act on neurons synapsing with the NECs or in the afferent or efferent limbs of the paths between chemosensors and central integration sites, this process remains elusive and may explain current discrepancies or species differences in the literature. To date it has been impossible to link the distribution of NECs to species sensitivity to different stimuli or fish lifestyles and while the gills have been shown to be the primary sensing site for respiratory gases, the location (gills, oro-branchial cavity or elsewhere) and orientation (external/water or internal/blood sensing) of the NECs are highly variable between species of water and air breathing fish. Much of what has been described so far comes from studies of hypoxic responses in fish, however, changes in CO2, ammonia and lactate have all been shown to elicit cardio-respiratory responses and all have been suggested to arise from stimulation of gill NECs. Our view of the role of NECs is broadening as we begin to understand the polymodal nature of these cells. We begin by presenting the fundamental picture of gill chemosensing that has developed, followed by some key unanswered questions about gill chemosensing in general.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"1-33"},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ammonia excretion by the fish gill: discoveries and ideas that shaped our current understanding. 鱼鳃的氨排泄：形成我们当前认识的发现和观点。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-10-01 Epub Date: 2024-06-07 DOI: 10.1007/s00360-024-01561-5

Alex M Zimmer

{"title":"Ammonia excretion by the fish gill: discoveries and ideas that shaped our current understanding.","authors":"Alex M Zimmer","doi":"10.1007/s00360-024-01561-5","DOIUrl":"10.1007/s00360-024-01561-5","url":null,"abstract":"The fish gill serves many physiological functions, among which is the excretion of ammonia, the primary nitrogenous waste in most fishes. Although it is the end-product of nitrogen metabolism, ammonia serves many physiological functions including acting as an acid equivalent and as a counter-ion in mechanisms of ion regulation. Our current understanding of the mechanisms of ammonia excretion have been influenced by classic experimental work, clever mechanistic approaches, and modern molecular and genetic techniques. In this review, I will overview the history of the study of ammonia excretion by the gills of fishes, highlighting the important advancements that have shaped this field with a nearly 100-year history. The developmental and evolutionary implications of an ammonia and gill-dominated nitrogen regulation strategy in most fishes will also be discussed. Throughout the review, I point to areas in which more work is needed to push forward this field of research that continues to produce novel insights and discoveries that will undoubtedly shape our overall understanding of fish physiology.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"697-715"},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The multifunctional fish gill. 多功能鱼鳃

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-10-01 Epub Date: 2024-09-23 DOI: 10.1007/s00360-024-01586-w

Steve F Perry, Bernd Pelster

引用次数: 0

Causes and consequences of gas bubble trauma on fish gill function. 气泡创伤对鱼鳃功能的影响和后果

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-10-01 Epub Date: 2024-03-07 DOI: 10.1007/s00360-024-01538-4

Naomi K Pleizier, Colin J Brauner

引用次数: 0

Endocrine control of gill ionocyte function in euryhaline fishes. 极海洋鱼类鳃离子细胞功能的内分泌控制

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-10-01 Epub Date: 2024-05-13 DOI: 10.1007/s00360-024-01555-3

Jason P Breves, Ciaran A Shaughnessy

{"title":"Endocrine control of gill ionocyte function in euryhaline fishes.","authors":"Jason P Breves, Ciaran A Shaughnessy","doi":"10.1007/s00360-024-01555-3","DOIUrl":"10.1007/s00360-024-01555-3","url":null,"abstract":"The endocrine system is an essential regulator of the osmoregulatory organs that enable euryhaline fishes to maintain hydromineral balance in a broad range of environmental salinities. Because branchial ionocytes are the primary site for the active exchange of Na+, Cl-, and Ca2+ with the external environment, their functional regulation is inextricably linked with adaptive responses to changes in salinity. Here, we review the molecular-level processes that connect osmoregulatory hormones with branchial ion transport. We focus on how factors such as prolactin, growth hormone, cortisol, and insulin-like growth-factors operate through their cognate receptors to direct the expression of specific ion transporters/channels, Na+/K+-ATPases, tight-junction proteins, and aquaporins in ion-absorptive (freshwater-type) and ion-secretory (seawater-type) ionocytes. While these connections have historically been deduced in teleost models, more recently, increased attention has been given to understanding the nature of these connections in basal lineages. We conclude our review by proposing areas for future investigation that aim to fill gaps in the collective understanding of how hormonal signaling underlies ionocyte-based processes.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"663-684"},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of structural remodelling on gill physiology. 结构重塑对鳃生理的影响

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-10-01 Epub Date: 2024-05-17 DOI: 10.1007/s00360-024-01558-0

Kathleen M Gilmour, Andy J Turko

{"title":"Effects of structural remodelling on gill physiology.","authors":"Kathleen M Gilmour, Andy J Turko","doi":"10.1007/s00360-024-01558-0","DOIUrl":"10.1007/s00360-024-01558-0","url":null,"abstract":"The complex relationships between the structure and function of fish gills have been of interest to comparative physiologists for many years. Morphological plasticity of the gill provides a dynamic mechanism to reversibly alter its structure in response to changes in the conditions experienced by the fish. The best known example of gill remodelling is the growth or retraction of cell masses between the lamellae, a rapid process that alters the lamellar surface area that is exposed to the water (i.e. the functional lamellar surface area). Decreases in environmental O2 availability and/or increases in metabolic O2 demand stimulate uncovering of the lamellae, presumably to increase the capacity for O2 uptake. This review addresses four questions about gill remodelling: (1) what types of reversible morphological changes occur; (2) how do these changes affect physiological function from the gill to the whole animal; (3) what factors regulate reversible gill plasticity; and (4) is remodelling phylogenetically widespread among fishes? We address these questions by surveying the current state of knowledge of gill remodelling in fishes, with a focus on identifying gaps in our understanding that future research should consider.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"595-609"},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The origins of gas exchange and ion regulation in fish gills: evidence from structure and function. 鱼鳃中气体交换和离子调节的起源：来自结构和功能的证据。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-10-01 Epub Date: 2024-03-26 DOI: 10.1007/s00360-024-01545-5

Michael A Sackville, J Andrew Gillis, Colin J Brauner

{"title":"The origins of gas exchange and ion regulation in fish gills: evidence from structure and function.","authors":"Michael A Sackville, J Andrew Gillis, Colin J Brauner","doi":"10.1007/s00360-024-01545-5","DOIUrl":"10.1007/s00360-024-01545-5","url":null,"abstract":"Gill function in gas exchange and ion regulation has played key roles in the evolution of fishes. In this review, we summarize data from the fields of palaeontology, developmental biology and comparative physiology for when and how the gills first acquired these functions. Data from across disciplines strongly supports a stem vertebrate origin for gas exchange structures and function at the gills with the emergence of larger, more active fishes. However, the recent discovery of putative ionocytes in extant cephalochordates and hemichordates suggests that ion regulation at gills might have originated much earlier than gas exchange, perhaps in the ciliated pharyngeal arches in the last common ancestor of deuterostomes. We hypothesize that the ancestral form of ion regulation served a filter-feeding function in the ciliated pharyngeal arches, and was later coopted in vertebrates to regulate extracellular ion and acid-base balance. We propose that future research should explore ionocyte homology and function across extant deuterostomes to test this hypothesis and others in order to determine the ancestral origins of ion regulation in fish gills.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"557-568"},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cell proliferation and regeneration in the gill. 鳃中的细胞增殖和再生 : 作者.

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-10-01 Epub Date: 2024-03-30 DOI: 10.1007/s00360-024-01548-2

Michael G Jonz

{"title":"Cell proliferation and regeneration in the gill.","authors":"Michael G Jonz","doi":"10.1007/s00360-024-01548-2","DOIUrl":"10.1007/s00360-024-01548-2","url":null,"abstract":"Seminal studies from the early 20th century defined the structural changes associated with development and regeneration of the gills in goldfish at the gross morphological and cellular levels using standard techniques of light and electron microscopy. More recently, investigations using cell lineage tracing, molecular biology, immunohistochemistry and single-cell RNA-sequencing have pushed the field forward and have begun to reveal the cellular and molecular processes that orchestrate cell proliferation and regeneration in the gills. The gill is a multifunctional organ that mediates an array of important physiological functions, including respiration, ion regulation and excretion of waste products. It is comprised of unique cell types, such as pavement cells, ionocytes, chemoreceptors and undifferentiated stem or progenitor cells that regulate growth and replenish cell populations. The gills develop from the embryonic endoderm and are rich in cell types derived from the neural crest. The gills have the capacity to remodel themselves in response to environmental change, such as in the case of ionocytes, chemoreceptors and the interlamellar cell mass, and can completely regenerate gill filaments and lamellae. Both processes of remodeling and regeneration invariably involve cell proliferation. Although gill regeneration has been reported in only a limited number of fish species, the process appears to have many similarities to regeneration of other organs in fish and amphibians. The present article reviews the studies that have described gill development and growth, and that demonstrate a suite of genes, transcription factors and other proteins involved in cell proliferation and regeneration in the gills.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"583-593"},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140330322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trace metals in the teleost fish gill: biological roles, uptake regulation, and detoxification mechanisms. 远洋鱼鳃中的痕量金属：生物作用、吸收调节和解毒机制。

IF 1.7 3区生物学

Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology Pub Date : 2024-10-01 Epub Date: 2024-06-25 DOI: 10.1007/s00360-024-01565-1

Raymond W M Kwong

{"title":"Trace metals in the teleost fish gill: biological roles, uptake regulation, and detoxification mechanisms.","authors":"Raymond W M Kwong","doi":"10.1007/s00360-024-01565-1","DOIUrl":"10.1007/s00360-024-01565-1","url":null,"abstract":"In fish, the gill plays a vital role in regulating the absorption of trace metals and is also highly susceptible to metal toxicity. Trace metals such as iron (Fe), copper (Cu), zinc (Zn), and manganese (Mn) are involved in various catalytic activities and molecular binding within the gill, thereby supporting a range of physiological processes in this organ. While beneficial at normal levels, these metals can become toxic when present in excess. Conversely, nonessential metals like cadmium (Cd) and lead (Pb) can gain entry into gill cells through similar metal transport pathways, potentially interfering with various cellular processes. The transepithelial transport of these metals across the gill epithelium is governed by a variety of metal transport and metal binding proteins. These include the Cu transporter 1 (CTR1), divalent metal transporter 1 (DMT1), and members of the Zrt-/Irt-like protein (ZIP) and zinc transport (ZnT) families. Additionally, some of these metals can compete with major ions (e.g., calcium, sodium) for absorption sites in the gill. This complex crosstalk suggests an interdependent mechanism that balances metal uptake to meet physiological needs while preventing excessive accumulation. In this article, I review the roles of trace metals in proteins/enzymes that support the different functions in the gill of teleost fish. I also discuss current understanding of the pathways involved in regulating the branchial uptake of metals and their influence on ionic regulation, and the potential detoxification mechanisms in the gill. Finally, I summarize knowledge gaps and potential areas for further investigation.","PeriodicalId":56033,"journal":{"name":"Journal of Comparative Physiology B-Biochemical Systems and Environmental Physiology","volume":" ","pages":"749-763"},"PeriodicalIF":1.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141447667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0