Faiz-Ul Hassan, Muhammad Safdar, Muhammad Younus, Muhammad Asif Arain
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Regulation of energy metabolism by non-coding RNAs in livestock species: a review.
The optimisation of livestock production relies on efficient energy metabolism. This review focused on elaborate regulatory processes governed by non-coding RNAs (ncRNAs), such as microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs). It explores the complex energy metabolism processes in livestock, elucidating the functions of ncRNAs in the expression of genes and pathways. miRNAs have been identified as significant regulators of glycolysis and glucose metabolism, whereas lncRNAs are known to affect adipogenesis and mitochondrial activity. Moreover, circRNAs have a substantial influence on the regulation of energy. In addition, this is not only enriching non-coding RNA-mediated energy control but also sheds light on possible applications. It is derived from its ability to condense complex molecular systems, thereby offering crucial insights to researchers. Through a comprehensive analysis of the intricate relationship between ncRNAs and energy metabolism, the information of this review provides a valuable framework for the implementation of focused interventions that hold the potential to significantly enhance the efficiency of livestock production.
期刊介绍:
The Journal of Comparative Physiology B publishes peer-reviewed original articles and reviews on the comparative physiology of invertebrate and vertebrate animals. Special emphasis is placed on integrative studies that elucidate mechanisms at the whole-animal, organ, tissue, cellular and/or molecular levels. Review papers report on the current state of knowledge in an area of comparative physiology, and directions in which future research is needed.