Frontiers in Integrative Neuroscience最新文献

{"title":"Differential contributions of body form, motion, and temporal information to subjective action understanding in naturalistic stimuli","authors":"Vojtěch Smekal, Marta Poyo Solanas, Evelyne I. C. Fraats, Beatrice de Gelder","doi":"10.3389/fnint.2024.1302960","DOIUrl":"https://doi.org/10.3389/fnint.2024.1302960","url":null,"abstract":"<sec><title>Introduction</title><p>We investigated the factors underlying naturalistic action recognition and understanding, as well as the errors occurring during recognition failures.</p></sec><sec><title>Methods</title><p>Participants saw full-light stimuli of ten different whole-body actions presented in three different conditions: as normal videos, as videos with the temporal order of the frames scrambled, and as single static representative frames. After each stimulus presentation participants completed one of two tasks—a forced choice task where they were given the ten potential action labels as options, or a free description task, where they could describe the action performed in each stimulus in their own words.</p></sec><sec><title>Results</title><p>While generally, a combination of form, motion, and temporal information led to the highest action understanding, for some actions form information was sufficient and adding motion and temporal information did not increase recognition accuracy. We also analyzed errors in action recognition and found primarily two different types.</p></sec><sec><title>Discussion</title><p>One type of error was on the semantic level, while the other consisted of reverting to the kinematic level of body part processing without any attribution of semantics. We elaborate on these results in the context of naturalistic action perception.</p></sec>","PeriodicalId":56016,"journal":{"name":"Frontiers in Integrative Neuroscience","volume":"73 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140105040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motor imagery in autism: a systematic review","authors":"Emma Gowen, Eve Edmonds, Ellen Poliakoff","doi":"10.3389/fnint.2024.1335694","DOIUrl":"https://doi.org/10.3389/fnint.2024.1335694","url":null,"abstract":"IntroductionMotor Imagery (MI) is when an individual imagines performing an action without physically executing that action and is thought to involve similar neural processes used for execution of physical movement. As motor coordination difficulties are common in autistic individuals it is possible that these may affect MI ability. The aim of this systematic review was to assess the current knowledge around MI ability in autistic individuals.MethodsA systematic search was conducted for articles published before September 2023, following PRISMA guidance. Search engines were PsycINFO, PubMed, Web of Science, Scopus, Wiley Online Library and PsyArXiv. Inclusion criteria included: (a) Original peer-reviewed and pre-print publications; (b) Autistic and a non-autistic group (c) Implicit or explicit imagery tasks (d) Behavioral, neurophysiological or self-rating measures, (e) Written in the English language. Exclusion criteria were (a) Articles only about MI or autism (b) Articles where the autism data is not presented separately (c) Articles on action observation, recognition or imitation only (d) Review articles. A narrative synthesis of the evidence was conducted.ResultsSixteen studies across fourteen articles were included. Tasks were divided into implicit (unconscious) or explicit (conscious) MI. The implicit tasks used either hand (6) or body (4) rotation tasks. Explicit tasks consisted of perspective taking tasks (3), a questionnaire (1) and explicit instructions to imagine performing a movement (2). A MI strategy was apparent for the hand rotation task in autistic children, although may have been more challenging. Evidence was mixed and inconclusive for the remaining task types due to the varied range of different tasks and, measures conducted and design limitations. Further limitations included a sex bias toward males and the hand rotation task only being conducted in children.DiscussionThere is currently an incomplete understanding of MI ability in autistic individuals. The field would benefit from a battery of fully described implicit and explicit MI tasks, conducted across the same groups of autistic children and adults. Improved knowledge around MI in autistic individuals is important for understanding whether MI techniques may benefit motor coordination in some autistic people.","PeriodicalId":56016,"journal":{"name":"Frontiers in Integrative Neuroscience","volume":"272 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139768378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autosomal recessive cerebellar ataxias: a diagnostic classification approach according to ocular features","authors":"Diego Lopergolo, Francesca Rosini, Elena Pretegiani, Alessia Bargagli, Valeria Serchi, Alessandra Rufa","doi":"10.3389/fnint.2023.1275794","DOIUrl":"https://doi.org/10.3389/fnint.2023.1275794","url":null,"abstract":"Autosomal recessive cerebellar ataxias (ARCAs) are a heterogeneous group of neurodegenerative disorders affecting primarily the cerebellum and/or its afferent tracts, often accompanied by damage of other neurological or extra-neurological systems. Due to the overlap of clinical presentation among ARCAs and the variety of hereditary, acquired, and reversible etiologies that can determine cerebellar dysfunction, the differential diagnosis is challenging, but also urgent considering the ongoing development of promising target therapies. The examination of afferent and efferent visual system may provide neurophysiological and structural information related to cerebellar dysfunction and neurodegeneration thus allowing a possible diagnostic classification approach according to ocular features. While optic coherence tomography (OCT) is applied for the parametrization of the optic nerve and macular area, the eye movements analysis relies on a wide range of eye-tracker devices and the application of machine-learning techniques. We discuss the results of clinical and eye-tracking oculomotor examination, the OCT findings and some advancing of computer science in ARCAs thus providing evidence sustaining the identification of robust eye parameters as possible markers of ARCAs.","PeriodicalId":56016,"journal":{"name":"Frontiers in Integrative Neuroscience","volume":"99 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139768400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioelectronic Medicine: a multidisciplinary roadmap from biophysics to precision therapies","authors":"María Alejandra González-González, Silvia V. Conde, Ramon Latorre, Stéphanie C. Thébault, Marta Pratelli, Nicholas C. Spitzer, Alexei Verkhratsky, Marie-Ève Tremblay, Cuneyt G. Akcora, Ana G. Hernández-Reynoso, Melanie Ecker, Jayme Coates, Kathleen L. Vincent, Brandy Ma","doi":"10.3389/fnint.2024.1321872","DOIUrl":"https://doi.org/10.3389/fnint.2024.1321872","url":null,"abstract":"<p>Bioelectronic Medicine stands as an emerging field that rapidly evolves and offers distinctive clinical benefits, alongside unique challenges. It consists of the modulation of the nervous system by precise delivery of electrical current for the treatment of clinical conditions, such as post-stroke movement recovery or drug-resistant disorders. The unquestionable clinical impact of Bioelectronic Medicine is underscored by the successful translation to humans in the last decades, and the long list of preclinical studies. Given the emergency of accelerating the progress in new neuromodulation treatments (i.e., drug-resistant hypertension, autoimmune and degenerative diseases), collaboration between multiple fields is imperative. This work intends to foster multidisciplinary work and bring together different fields to provide the fundamental basis underlying Bioelectronic Medicine. In this review we will go from the biophysics of the cell membrane, which we consider the inner core of neuromodulation, to patient care. We will discuss the recently discovered mechanism of neurotransmission switching and how it will impact neuromodulation design, and we will provide an update on neuronal and glial basis in health and disease. The advances in biomedical technology have facilitated the collection of large amounts of data, thereby introducing new challenges in data analysis. We will discuss the current approaches and challenges in high throughput data analysis, encompassing big data, networks, artificial intelligence, and internet of things. Emphasis will be placed on understanding the electrochemical properties of neural interfaces, along with the integration of biocompatible and reliable materials and compliance with biomedical regulations for translational applications. Preclinical validation is foundational to the translational process, and we will discuss the critical aspects of such animal studies. Finally, we will focus on the patient point-of-care and challenges in neuromodulation as the ultimate goal of bioelectronic medicine. This review is a call to scientists from different fields to work together with a common endeavor: accelerate the decoding and modulation of the nervous system in a new era of therapeutic possibilities.</p>","PeriodicalId":56016,"journal":{"name":"Frontiers in Integrative Neuroscience","volume":"11 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139902849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurophysiological markers of asymmetric emotional contagion: implications for organizational contexts","authors":"Sarah Boukarras, Donato Ferri, Laura Borgogni, Salvatore Maria Aglioti","doi":"10.3389/fnint.2024.1321130","DOIUrl":"https://doi.org/10.3389/fnint.2024.1321130","url":null,"abstract":"<p>Emotions play a vital role within organizations, impacting various crucial aspects of work such as job satisfaction, performance, and employee well-being. Understanding how emotional states spread in organizational settings is therefore essential. Recent studies have highlighted that a leader’s emotional state can influence their followers, with significant consequences on job performance. Leaders thus possess the ability to influence their employees’ psychological state and, consequently, their well-being. However, the biological underpinnings of emotional contagion from leaders to followers remain unexplored. The field of interpersonal (neuro)physiology, which involves recording brain and peripheral activity of multiple individuals during interactions, holds great potential for investigating this phenomenon. Analyzing the time-lagged synchronization of neurophysiological activity during interactions may serve as a measure of the leader’s influence on their followers in organizational contexts. In this “mini review,” we examine empirical studies that have employed interpersonal (neuro)physiology to quantify the asymmetrical contagion of emotions in different contexts. Asymmetrical contagion was operationalized as the unidirectional influence exerted by one individual (i.e., the “sender”) to another one (i.e., the “receiver”), whereby the receiver’s state can be predicted by the sender’s one. The reviewed literature reveals that delayed synchronization of physiological states is a widespread phenomenon that may underpin the transmission of emotions. These findings have significant implications for various aspects of organizational life, including leader-to-employee communication, and could drive the development of effective leadership training programs. We propose that Organizational Neuroscience may benefit from including interpersonal neurophysiology in its methodological toolkit for laboratory and field studies of leader-follower dynamics.</p>","PeriodicalId":56016,"journal":{"name":"Frontiers in Integrative Neuroscience","volume":"4 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139579184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lasting mesothalamic dopamine imbalance and altered exploratory behavior in rats after a mild neonatal hypoxic event","authors":"Barbara Nikolic, Sara Trnski-Levak, Kristina Kosic, Matea Drlje, Ivan Banovac, Dubravka Hranilovic, Natasa Jovanov-Milosevic","doi":"10.3389/fnint.2023.1304338","DOIUrl":"https://doi.org/10.3389/fnint.2023.1304338","url":null,"abstract":"<sec><title>Introduction</title><p>Adversities during the perinatal period can decrease oxygen supply to the fetal brain, leading to various hypoxic brain injuries, which can compromise the regularity of brain development in different aspects. To examine the catecholaminergic contribution to the link between an early-life hypoxic insult and adolescent behavioral aberrations, we used a previously established rat model of perinatal hypoxia but altered the hypobaric to normobaric conditions.</p></sec><sec><title>Methods</title><p>Exploratory and social behavior and learning abilities were tested in 70 rats of both sexes at adolescent age. Inherent vertical locomotion, sensory-motor functions and spatial learning abilities were explored in a subset of animals to clarify the background of altered exploratory behavior. Finally, the concentrations of dopamine (DA) and noradrenaline in midbrain and pons, and the relative expression of genes for DA receptors D1 and D2, and their down-stream targets (DA- and cAMP-regulated phosphoprotein, Mr 32 kDa, the regulatory subunit of protein kinase A, and inhibitor-5 of protein phosphatase 1) in the hippocampus and thalamus were investigated in 31 rats.</p></sec><sec><title>Results</title><p>A lesser extent of alterations in exploratory and cognitive aspects of behavior in the present study suggests that normobaric conditions mitigate the hypoxic injury compared to the one obtained under hypobaric conditions. Increased exploratory rearing was the most prominent consequence, with impaired spatial learning in the background. In affected rats, increased midbrain/pons DA content, as well as mRNA levels for DA receptors and their down-stream elements in the thalamus, but not the hippocampus, were found.</p></sec><sec><title>Conclusion</title><p>We can conclude that a mild hypoxic event induced long-lasting disbalances in mesothalamic DA signaling, contributing to the observed behavioral alterations. The thalamus was thereby indicated as another structure, besides the well-established striatum, involved in mediating hypoxic effects on behavior through DA signaling.</p></sec>","PeriodicalId":56016,"journal":{"name":"Frontiers in Integrative Neuroscience","volume":"11 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139481225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrinsic functional clustering of the macaque insular cortex","authors":"Lotte Sypré, Saloni Sharma, Dante Mantini, Koen Nelissen","doi":"10.3389/fnint.2023.1272529","DOIUrl":"https://doi.org/10.3389/fnint.2023.1272529","url":null,"abstract":"<p>The functional organization of the primate insula has been studied using a variety of techniques focussing on regional differences in either architecture, connectivity, or function. These complementary methods offered insights into the complex organization of the insula and proposed distinct parcellation schemes at varying levels of detail and complexity. The advent of imaging techniques that allow non-invasive assessment of structural and functional connectivity, has popularized data-driven connectivity-based parcellation methods to investigate the organization of the human insula. Yet, it remains unclear if the subdivisions derived from these data-driven clustering methods reflect meaningful descriptions of the functional specialization of the insula. In this study, we employed hierarchical clustering to examine the cluster parcellations of the macaque insula. As our aim was exploratory, we examined parcellations consisting of two up to ten clusters. Three different cluster validation methods (fingerprinting, silhouette, elbow) converged on a four-cluster solution as the most optimal representation of our data. Examining functional response properties of these clusters, in addition to their brain-wide functional connectivity suggested a functional specialization related to processing gustatory, somato-motor, vestibular and social visual cues. However, a more detailed functional differentiation aligning with previous functional investigations of insula subfields became evident at higher cluster numbers beyond the proposed optimal four clusters. Overall, our findings demonstrate that resting-state-based hierarchical clustering can provide a meaningful description of the insula’s functional organization at some level of detail. Nonetheless, cluster parcellations derived from this method are best combined with data obtained through other modalities, to provide a more comprehensive and detailed account of the insula’s complex functional organization.</p>","PeriodicalId":56016,"journal":{"name":"Frontiers in Integrative Neuroscience","volume":"19 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139104170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brain structure and function: a multidisciplinary pipeline to study hominoid brain evolution","authors":"Angela D. Friederici, Roman M. Wittig, Alfred Anwander, Cornelius Eichner, Tobias Gräßle, Carsten Jäger, Evgeniya Kirilina, Ilona Lipp, Ariane Düx, Luke J. Edwards, Cédric Girard-Buttoz, Anna Jauch, Kathrin S. Kopp, Michael Paquette, Kerrin J. Pine, Steve Unwin, Daniel B. M. Haun, Fabian H. Leendertz, Richard McElreath, Markus Morawski, Philipp Gunz, Nikolaus Weiskopf, Catherine Crockford, EBC Consortium, Daniel Ashoff, Karoline Albig, Bala Amarasekaran, Sam Angedakin, Alfred Anwander, Caroline Asiimwe, Christian Bock, Birgit Blazey, Andreas Bernhard, Jacinta C Beehner, Laurent Bailanda, Raphael Belais, Thore J Bergman, Denny Böttcher, Tatiana Bortolato, Penelope Carlier, Julian Chantrey, Catherine Crockford, Daniela Denk, Tobias Deschner, Ariane Düx, Luke J. Edwards, Cornelius Eichner, Dag Encke, Gelardine Escoubas, Malak Ettaj, Pawel Fedurek, Karina Flores, Alejandra Romero Florero, Richard Franke, Angela D Friederici, Cedric Girard-Buttoz, Jorge Gomez Fortun, Tobias Gräßle, Eva Gruber-Dujardin, Philipp Gunz, Susan Hambrecht, Florian Hansmann, Jess Hartel, Daniel BM Haun, Michael Henshall, Catherine Hobaiter, Noémie Hofman, Jennifer E Jaffe, Carsten Jäger, Anna Jauch, Stomy Karhemere, Evgenya Kirilina, Robert Klopfleisch, Tobias Knauf-Witzens, Kathrin Kopp, Bastian Lange, Kevin E Langergraber, Arne Lawrenz, Kevin Lee, Fabian H Leendertz, Illona Lipp, Matyas Liptovszky, Christelle Patricia Lumbu, Patrice Makouloutou Nzassi, Guy Landry Mamboundou Kouima, Kerstin Mätz-Rensing, Richard McElreath, Zoltan Mezö, Fanny Minesi, Sophie Moittie, Torsten Møller, Markus Morawski, Dave Morgan, Mathias Müller, Timothy Mugabe, Martin Muller, Karin Olofsson-Sannö, Alain Ondzie, Emily Otali, Michael Paquette, Simone Pika, Kerrin J. Pine, Andrea Pizarro, Kamilla Pleh, Sandra Reichler-Danielowski, Jessica Rendel, Martha M Robbins, Konstantin Ruske, Liran Samuni, Crickette Sanz, Jan Schinköthe, André Schüle, Ingo Schwabe, Katarina Schwalm, Anistan Sebastiampillai, Lara Southern, Sheri Speede, Jonas Steiner, Mark F Stidworthy, Martin Surbeck, Claudia A. Szentiks, Tanguy Tanga, Tobias Loubser Theron, Reiner Ulrich, Steve Unwin, Erica van de Waal, Sue Walker, Nikolaus Weiskopf, Gudrun Wibbelt, Navena Widulin, Hermann Will, Roman M Wittig, Kim Wood, Emiliano Zaccarella, Klaus Zuberbühler","doi":"10.3389/fnint.2023.1299087","DOIUrl":"https://doi.org/10.3389/fnint.2023.1299087","url":null,"abstract":"<p>To decipher the evolution of the hominoid brain and its functions, it is essential to conduct comparative studies in primates, including our closest living relatives. However, strong ethical concerns preclude <italic>in vivo</italic> neuroimaging of great apes. We propose a responsible and multidisciplinary alternative approach that links behavior to brain anatomy in non-human primates from diverse ecological backgrounds. The brains of primates observed in the wild or in captivity are extracted and fixed shortly after natural death, and then studied using advanced MRI neuroimaging and histology to reveal macro- and microstructures. By linking detailed neuroanatomy with observed behavior within and across primate species, our approach provides new perspectives on brain evolution. Combined with endocranial brain imprints extracted from computed tomographic scans of the skulls these data provide a framework for decoding evolutionary changes in hominin fossils. This approach is poised to become a key resource for investigating the evolution and functional differentiation of hominoid brains.</p>","PeriodicalId":56016,"journal":{"name":"Frontiers in Integrative Neuroscience","volume":"22 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139396440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential uses of auditory nerve stimulation to modulate immune responses in the inner ear and auditory brainstem","authors":"Benjamin J. Seicol, Zixu Guo, Katy Garrity, Ruili Xie","doi":"10.3389/fnint.2023.1294525","DOIUrl":"https://doi.org/10.3389/fnint.2023.1294525","url":null,"abstract":"<p>Bioelectronic medicine uses electrical stimulation of the nervous system to improve health outcomes throughout the body primarily by regulating immune responses. This concept, however, has yet to be applied systematically to the auditory system. There is growing interest in how cochlear damage and associated neuroinflammation may contribute to hearing loss. In conjunction with recent findings, we propose here a new perspective, which could be applied alongside advancing technologies, to use auditory nerve (AN) stimulation to modulate immune responses in hearing health disorders and following surgeries for auditory implants. In this article we will: (1) review the mechanisms of inflammation in the auditory system in relation to various forms of hearing loss, (2) explore nerve stimulation to reduce inflammation throughout the body and how similar neural-immune circuits likely exist in the auditory system (3) summarize current methods for stimulating the auditory system, particularly the AN, and (4) propose future directions to use bioelectronic medicine to ameliorate harmful immune responses in the inner ear and auditory brainstem to treat refractory conditions. We will illustrate how current knowledge from bioelectronic medicine can be applied to AN stimulation to resolve inflammation associated with implantation and disease. Further, we suggest the necessary steps to get discoveries in this emerging field from bench to bedside. Our vision is a future for AN stimulation that includes additional protocols as well as advances in devices to target and engage neural-immune circuitry for therapeutic benefits.</p>","PeriodicalId":56016,"journal":{"name":"Frontiers in Integrative Neuroscience","volume":"90 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138630053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Bridging the gap: implementing building blocks of the nervous system to simulate neuronal functions at different levels.","authors":"Yasuhito Watanabe, Yutaka Sakaguchi, Janet L Paluh","doi":"10.3389/fnint.2023.1335723","DOIUrl":"https://doi.org/10.3389/fnint.2023.1335723","url":null,"abstract":"","PeriodicalId":56016,"journal":{"name":"Frontiers in Integrative Neuroscience","volume":"17 ","pages":"1335723"},"PeriodicalIF":3.5,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10716425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138812297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}