Przeglad MenopauzalnyPub Date : 2024-03-01Epub Date: 2024-03-17DOI: 10.5114/pm.2024.136327
Ainur Donayeva, Ainur Amanzholkyzy, Ibrahim A Abdelazim, Saule Rakhyzhanova, Akzhunus Mannapova, Talgar Abilov, Zaituna Khamidullina, Karlygash Bimagambetova, Gulnara Gubasheva, Dinara Kulzhanova, Akbayan Turesheva, Samat Saparbayev
{"title":"The relationship between vitamin D and adolescents' parathyroid hormone and bone mineral density.","authors":"Ainur Donayeva, Ainur Amanzholkyzy, Ibrahim A Abdelazim, Saule Rakhyzhanova, Akzhunus Mannapova, Talgar Abilov, Zaituna Khamidullina, Karlygash Bimagambetova, Gulnara Gubasheva, Dinara Kulzhanova, Akbayan Turesheva, Samat Saparbayev","doi":"10.5114/pm.2024.136327","DOIUrl":"https://doi.org/10.5114/pm.2024.136327","url":null,"abstract":"<p><strong>Introduction: </strong>To detect the relationship between 25-hydroxy vitamin D (25(OH)D) and adolescents' parathyroid hormone (PTH) and bone mineral density (BMD).</p><p><strong>Material and methods: </strong>Two hundred adolescent girls were recruited for this cross-sectional comparative study. After detailed evaluation, a pelvic sonography was performed for the studied adolescents to rule out any pelvic pathology. Adolescents' blood samples were collected to measure the thyroid stimulating hormone, prolactin, glycosylated haemoglobin (HbA<sub>1C</sub>), PTH, and 25(OH)D. The studied adolescents' BMD and the T-score were evaluated at 2 anatomical sites. The studied adolescents were classified according to their serum 25(OH)D into 2 groups: a 25(OH)D-deficient group (study group; 25(OH)D < 20 ng/ml) and normal controls (25(OH)D > 30 ng/ml). Student's t-test was used for analysis of the studied adolescents' variables, and correlation analysis (Pearson`s correlation) was used to detect the relationship between 25(OH)D and adolescents' PTH and BMD.</p><p><strong>Results: </strong>The parathyroid hormone was statistically higher in the 25(OH)D-deficient group than in the normal controls (41.3 ±3.4 pg/ml vs. 21.1 ±2.8) (<i>p</i> = 0.02), and the BMD was statistically lower in the 25(OH)D-deficient group than in the normal controls (-1.25 ±0.5 vs. 0.3 ±0.4) (<i>p</i> = 0.01). The 25(OH)D had a significant negative correlation with the adolescents' PTH (<i>r</i> = -0.9175; p < 0.00001) and a significant positive correlation with the adolescents' BMD (<i>r</i> = 0.756; <i>p</i> < 0.00001). The parathyroid hormone had a significant negative correlation with the adolescents' BMD (<i>r</i> = -0.7006; <i>p</i> < 0.00001).</p><p><strong>Conclusions: </strong>The parathyroid hormone in this study had significant negative correlations with both 25(OH)D and BMD. The 25(OH)D had a significant positive correlation with the studied adolescents' BMD.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"23 1","pages":"1-5"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11056728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2023-12-01Epub Date: 2023-11-29DOI: 10.5114/pm.2023.133280
Ainur Donayeva, Dinara Kulzhanova, Ainur Amanzholkyzy, Ibrahim A Abdelazim, Talgar Abilov, Zhenisbek Baubekov, Ihab I Samaha
{"title":"Relationship between vitamin D and adolescents' hypothyroidism - a cross-sectional study.","authors":"Ainur Donayeva, Dinara Kulzhanova, Ainur Amanzholkyzy, Ibrahim A Abdelazim, Talgar Abilov, Zhenisbek Baubekov, Ihab I Samaha","doi":"10.5114/pm.2023.133280","DOIUrl":"10.5114/pm.2023.133280","url":null,"abstract":"<p><strong>Introduction: </strong>To detect the relationship between 25(OH)D and hypothyroidism in adolescents.</p><p><strong>Material and methods: </strong>A total of 180 adolescents were included in the current study, which was conducted in West Kazakhstan (Aktobe) over 2 years. After thorough evaluation, blood samples were collected from the studied participants to measure the thyroid stimulating hormone (TSH), free thyroxine (T4), prolactin, glycosylated haemoglobin, and 25(OH)D. Participants were classified into a 25(OH)D-deficient group (study group) and controls. MedCalc and correlation analysis (Pearson's correlation) were used to detect the odds of hypothyroidism and the relationship between 25(OH)D and adolescents' hypothyroidism, respectively.</p><p><strong>Results: </strong>Thyroid-stimulating hormone was statistically higher in the 25(OH)D-deficient group than in the normal controls (3.71 ±1.4 mIU/ml vs. 2.67 ±0.99) (<i>p</i> = 0.0006), and the free T4 was statistically lower in the 25(OH)D-deficient group than in normal controls (1.4 ±0.56 ng/ml vs. 1.5 ±0.4) (<i>p</i> = 0.0008). The 25(OH)D deficient group had higher odds of subclinical (OR 4.89; <i>p</i> = 0.016), and clinical hypothyroidism (OR 4.3; <i>p</i> = 0.013) compared to controls. A significant negative correlation between the 25(OH)D and TSH (<i>r</i> = -0.793; <i>p</i> < 0.00001), and a significant positive correlation between the 25(OH)D and free T4 (<i>r</i> 0.55; <i>p</i> < 0.00001) were detected in this study.</p><p><strong>Conclusions: </strong>The thyroid-stimulating hormone was statistically higher and the free T4 was statistically lower in the 25(OH)D-deficient group than in normal controls. The 25(OH)D-deficient group had higher odds of both subclinical and clinical hypothyroidism compared to controls. A significant negative correlation between the 25(OH)D and TSH, and a significant positive correlation between the 25(OH)D and the free T4 were detected in this study.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"22 4","pages":"186-190"},"PeriodicalIF":1.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10793608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A survey of the psychosocial impact of the COVID-19 pandemic on pregnant women attending a tertiary care centre of Eastern India - a cross-sectional study.","authors":"Abhipsa Rath, Pallabi Nayak, Jasmina Begum, Subarna Mitra","doi":"10.5114/pm.2023.133593","DOIUrl":"10.5114/pm.2023.133593","url":null,"abstract":"<p><strong>Introduction: </strong>The COVID-19 pandemic presented an unprecedented challenge, and, as during the SARS outbreak in 2002, there was scope of overestimation of risk by pregnant women, leading to increased fear and anxiety. The aim of this study was to assess the psychosocial impact of the pandemic on pregnant women so better-informed decisions can be taken to spread awareness and alleviate their anxieties.</p><p><strong>Material and methods: </strong>This was a cross-sectional study in a single tertiary care centre of Eastern India including 292 participants. The inclusion criteria were all pregnant women of any gestational age attending the All India Institute of Medical Sciences, Bhubaneswar for antenatal check-up or delivery. The exclusion criteria were patients with severe morbidities and patients not willing to participate. The primary outcome was to determine the psychosocial impact of the COVID-19 pandemic on pregnant women and to measure the anxiety level of pregnant women during the COVID-19 crisis. The secondary outcome was to determine the correlation between demographic aspects and psychosocial impact of COVID-19 pandemic on pregnant women.</p><p><strong>Results: </strong>A self-designed questionnaire was used. Anxiety was scored using the generalised anxiety disorder scale. More than half the participants (57.9%) were not at all worried about acquiring the infection. Of all, 99.3% were scored to have no anxiety and 0.7% had moderate anxiety. Significant association of the level of anxiety was found with living with people at high risk of contracting the disease (<i>p</i> = 0.002).</p><p><strong>Conclusions: </strong>The widespread awareness activities were effective and successful, as the pregnant women at the grassroots level faced minimal anxiety and were aware and assured. Studies like this help to provide feedback and formulate educational activities in future pandemics. The change in the effect on people, from panic in the previous pandemics to assurance in the current one, as found in our study, indicates the commendable work done to spread well founded information far and wide by the government, health care institutions, and workers.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"22 4","pages":"196-201"},"PeriodicalIF":1.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10793613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2023-12-01Epub Date: 2023-12-11DOI: 10.5114/pm.2023.133594
Omnia B Bakr, Alaa H El-Feky, Ibrahim A Abdelazim, Rania G El-Skaan
{"title":"Menstrual changes after the thrombo-prophylaxis or anticoagulants used during the COVID-19 infection.","authors":"Omnia B Bakr, Alaa H El-Feky, Ibrahim A Abdelazim, Rania G El-Skaan","doi":"10.5114/pm.2023.133594","DOIUrl":"10.5114/pm.2023.133594","url":null,"abstract":"<p><strong>Introduction: </strong>To detect the menstrual changes after the thrombo-prophylaxis or anticoagulants used during the COVID-19 infection.</p><p><strong>Material and methods: </strong>A total of 176 diagnosed with COVID-19 infection, were included in this retrospective study after giving informed consent. Participants were asked to complete an online questionnaire, and the collected participants` data were analysed using the χ<sup>2</sup> test to detect the menstrual changes after the thrombo-prophylaxis or anticoagulants used during the COVID-19 infection.</p><p><strong>Results: </strong>The number of participants` number who reported menstrual flow for 2 to < 5 days, and menstrual flow > 7 days after the COVID-19 infection [31/176 (17.6%), and 42/176 (23.9%), respectively] was significantly higher compared to the number of participants` who reported menstrual flow for 2 to < 5 days, and menstrual flow > 7 days before the COVID-19 infection [12/176 (6.8%), and 15/176 (8.5%), respectively], (<i>p</i> = 0.005, and 0.0009, respectively). The use of thrombo-prophylaxis or anticoagulants during the COVID-19 infection was also associated with significant menstrual pattern changes (37.8% increased menstrual flow, 18.5% menstrual flow for 2 to < 5 days, 59.7% menstrual flow > 7 days, 5.9% contact bleeding, and 6.7% abnormal menstrual pattern for one cycle).</p><p><strong>Conclusions: </strong>Significant menstrual changes were observed in this study after the COVID-19 infection infection (17.6% reported menstrual flow for 2 to < 5 days, and 23.9% reported menstrual flow > 7 days). The use of thrombo-prophylaxis or anticoagulants during the COVID-19 infection infection was associated with significant menstrual changes (37.8% increased menstrual flow, 18.5% menstrual flow for 2 to < 5 days, 59.7% menstrual flow > 7 days, 5.9% contact bleeding, and 6.7% abnormal menstrual pattern for one cycle).</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"22 4","pages":"179-185"},"PeriodicalIF":1.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10793612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2023-12-01Epub Date: 2023-12-21DOI: 10.5114/pm.2023.133883
Ainur Amanzholkyzy, Ainur Donayeva, Dinara Kulzhanova, Ibrahim A Abdelazim, Talgar Abilov, Zhenisbek Baubekov, Ihab I Samaha
{"title":"Relation between vitamin D and adolescents' serum prolactin.","authors":"Ainur Amanzholkyzy, Ainur Donayeva, Dinara Kulzhanova, Ibrahim A Abdelazim, Talgar Abilov, Zhenisbek Baubekov, Ihab I Samaha","doi":"10.5114/pm.2023.133883","DOIUrl":"10.5114/pm.2023.133883","url":null,"abstract":"<p><strong>Introduction: </strong>To detect whether there is a relation between vitamin D (Vit. D) and adolescents' serum prolactin (PRL) or not.</p><p><strong>Material and methods: </strong>Hundred and seventy-six adolescent girls were recruited for the current study, which was conducted in West Kazakhstan (Aktobe) over two years. After thorough evaluation, blood samples were taken from adolescents to measure thyroid stimulating hormone (TSH), free thyroxine (T4), PRL, glycosylated hemoglobin and 25(OH)D. The studied adolescents were classified into study group [25(OH)D deficient] and controls [normal 25(OH)D]. The acquired adolescents' variables were analyzed using the Student <i>t</i>-test and Pearson's correlation.</p><p><strong>Results: </strong>The serum TSH and PRL were statistically higher in the study group than normal controls (3.73 ±1.45 mIU/ml and 47.5 ±7.6 ng/ml vs. 2.67 ±1.0 and 10.8 ±5.1, respectively), (<i>p</i> = 0.0003 and <i>p</i> = 0.0001, respectively). The free T4 was statistically lower in the study group than normal controls (1.4 ±0.6 ng/ml vs. 1.5 ±0.4), (<i>p</i> = 0.0001). Strong negative associations between the serum PRL and 25(OH)D [<i>r</i> = -0.803 (<i>p</i> < 0.00001)], and between the serum PRL and free T4 [<i>r</i> = -0.6959 (<i>p</i> < 0.00001)] were detected in this study. Additionally, there was a strong positive association between the serum PRL and TSH [<i>r</i> = 0.8137 (<i>p</i> < 0.00001)].</p><p><strong>Conclusions: </strong>A strong negative association between the serum PRL and 25(OH)D and a strong positive association between the serum PRL and TSH were detected in this study. This study recommends further studies to confirm the relation between Vit. D and PRL and screening Vit. D deficient adolescents for PRL and thyroid disorders.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"22 4","pages":"202-206"},"PeriodicalIF":1.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10793607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2023-12-01Epub Date: 2023-12-21DOI: 10.5114/pm.2023.133847
Ihab I Samaha, Zaituna Khamidullina, Ibrahim A Abdelazim
{"title":"Relationship between routine urinary catheterization and postoperative urinary symptoms and urinary tract infections in women undergoing elective caesarean section.","authors":"Ihab I Samaha, Zaituna Khamidullina, Ibrahim A Abdelazim","doi":"10.5114/pm.2023.133847","DOIUrl":"10.5114/pm.2023.133847","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the study was to detect the relationship between routine urinary catheterization and postoperative urinary symptoms and urinary tract infections (UTIs) in women undergoing elective caesarean sections (ECSs).</p><p><strong>Material and methods: </strong>One hundred women undergoing ECSs were included in this observational study and randomized into a catheterized (C) group, including women who underwent ECS after insertion of indwelling Foley's catheter, and a non-catheterized (NC) group, including women who underwent ECS without Foley's catheter. The Foley's catheters were removed from all participants in the C group once they were freely ambulant and had recovered from the effect of the spinal anaesthesia. Participants were asked about any abnormal postoperative urinary symptoms (dysuria, frequency, urgency, and/or urinary retention), and to collect urine samples (mid-stream) once they were freely ambulant for urine cultures.</p><p><strong>Results: </strong>The postoperative dysuria, frequency, and urgency were significantly higher in the C group compared to the NC group [36% (18/50), 40% (20/50), and 34% (17/50) vs. 8% (4/50), 6% (3/50), and 6% (3/50), respectively], (<i>p</i> = 0.006, 0.001 and 0.004, respectively). The urinary tract infections and the postoperative antimicrobials used were significantly higher in the C group compared to the NC group [40% (20/50) and 40% (20/50) vs. 6% (3/50) and 6% (3/50), respectively], (<i>p</i> = 0.001 and 0.001, respectively). The postoperative hospital-stay after the ECSs was significantly higher in the C group compared to the NC group (5.4 ±1.8 days vs. 3.8 ±1.15, respectively), (<i>p</i> = 0.001).</p><p><strong>Conclusions: </strong>Routine urinary catheterizations in women undergoing ECS significantly increase the odds of postoperative dysuria, frequency, urgency, UTIs, and the postoperative antimicrobials used.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"22 4","pages":"207-212"},"PeriodicalIF":2.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10793614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A very rare case of echinococcus granulosus arising in the ovary and the uterus.","authors":"Angel Yordanov, Rosen Boncev, Stoyan Kostov, Yavor Kornovski, Yonka Ivanova, Stanislav Slavchev, Venelina Todorova, Konstantina Karakadieva, Lazar Tranchev, Mariela Vasileva-Slaveva","doi":"10.5114/pm.2023.133791","DOIUrl":"10.5114/pm.2023.133791","url":null,"abstract":"<p><p>Hydatidosis is a zoonosis caused by the larval form of a cestode of the species Echinococcus granulosus, the canine tapeworm. It can affect any organ of the human body except nails, hair, and cornea. It most often involves the liver, lungs, muscles, and bones. Involvement of organs in the small pelvis is extremely rare, mainly secondary to dissemination of hydatidosis from another organ, and the ovaries are most often involved, followed by the uterus. We present a 41-year-old Caucasian woman with complaints of mild pain, heaviness in the small pelvis, and a fibroid detected by ultrasound examination. She had reported for 2 previous operations for echinococcus cysts, and we found cystic formations in the liver and pelvis by computed tomography. It was decided that it is a recurrence of echinococcosis with a new cyst both in ovary and uterus. A hysterectomy with adnexectomy was performed, and one year later there is no evidence of recurrence of echinococcosis. In the presence of a formation in the small pelvis, one should always think about echinococcosis, especially if there is evidence of previous manifestations of the disease. Diagnosing this disease is extremely important for proper treatment. As rare as uterine involvement is, this possibility should not be overlooked.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"22 4","pages":"236-239"},"PeriodicalIF":1.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10793605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2023-12-01Epub Date: 2023-12-21DOI: 10.5114/pm.2023.133867
Lavanya N, Sathyaprabha B
{"title":"Physical activity, anthropometric measurements, quality of life and menopausal symptoms among South-Indian women.","authors":"Lavanya N, Sathyaprabha B","doi":"10.5114/pm.2023.133867","DOIUrl":"10.5114/pm.2023.133867","url":null,"abstract":"<p><strong>Introduction: </strong>Menopause is the period when the reproductive capacity ceases in women's life. A wide range of symptoms occur as a consequence of estrogen decrease during menopause. Evidence suggests that physically active women have a better quality of life (QoL) and fewer menopausal symptoms. The aim of the study was to analyze the relationship between physical activity (PA), anthropometric measurements, QoL and menopausal symptoms.</p><p><strong>Material and method: </strong>A cross-sectional study was conducted online through WhatsApp and Facebook and via email among menopausal women (April 2021 - June 2021). In total 168 responses were received; 153 responses were included in the study based on the inclusion criteria. Participants were asked to complete the details of anthropometric measurements, the Menopause Rating Scale (MRS), the International Physical Activity Questionnaire and the Menopause-Specific Quality of Life Questionnaire (MENQOL).</p><p><strong>Results: </strong>The majority of menopausal women complained of one or more symptoms in the MRS. A statistically significant difference was noted between the body mass index (BMI) and the menopausal symptoms such as irritability and depressive mood. There was an association between PA and MENQOL physical and sexual domains (<i>p</i>-value ≤ 0.05).</p><p><strong>Conclusions: </strong>There was an association between PA, menopausal symptoms, BMI and MENQOL physical and sexual domains. Hence, moderate PA promotion is recommended among middle aged women to have a healthy menopausal transition.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"22 4","pages":"191-195"},"PeriodicalIF":1.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10793610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2023-12-01Epub Date: 2023-12-18DOI: 10.5114/pm.2023.133828
Oksana Pavlovska, Olga Savelyeva, Kateryna Pavlovska
{"title":"Genitourinary syndrome of menopause and intestinal microbiota.","authors":"Oksana Pavlovska, Olga Savelyeva, Kateryna Pavlovska","doi":"10.5114/pm.2023.133828","DOIUrl":"10.5114/pm.2023.133828","url":null,"abstract":"<p><strong>Introduction: </strong>Genitourinary syndrome of menopause (GSM) is one of the pathological symptoms of menopause, which causes significant physical, psycho-emotional, and sexual discomfort to a woman.</p><p><strong>Material and methods: </strong>The study describes an examination of 65 middle-aged women, who were divided into 2 groups. Group I included 39 patients with GSM, who, depending on the duration of symptoms (3-5 years, more than 7 years), were divided into subgroups Ia and Ib. Group II included 26 patients who did not have clinical manifestations of GSM. All patients underwent general clinical studies. Bacteriological examination of faeces was used to assess the state of the intestinal microbiota.</p><p><strong>Results: </strong>It was found that menopause occurred in women with GSM earlier, compared with patients without manifestations of urogenital disorders. Also, the women with GSM were more likely to be diagnosed with type 2 diabetes mellitus, metabolic syndrome, overweight, and iron deficiency anaemia. When analysing the results of a bacteriological study in this group of patients, a statistically significant decrease in the colonization of <i>Bifidobacterium</i> and <i>Lactobacillus</i>, as well as excessive bacterial growth of such conditionally pathogenic bacteria as <i>Escherichia coli</i> with reduced enzymatic activity, and <i>Klebsiella</i> and <i>Streptococcus</i> was revealed. Conclusions: Conducting a fundamental study on the characteristics of the intestinal microbiota in menopausal disorders will be an important step towards understanding the pathogenetic mechanisms of their formation, and correction of intestinal metabolism can become an important condition for effective prevention and treatment.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"22 4","pages":"213-219"},"PeriodicalIF":1.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10793611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139492719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2023-12-01Epub Date: 2023-12-11DOI: 10.5114/pm.2023.133570
Danielly Yani Fausto, Julia Beatriz Bocchi Martins, Juliana da Silveira, Fernando Luiz Cardoso, Adriana Coutinho de Azevedo Guimarães
{"title":"Association between menopausal symptoms, sexual function, and sexual activity - a cross-sectional study.","authors":"Danielly Yani Fausto, Julia Beatriz Bocchi Martins, Juliana da Silveira, Fernando Luiz Cardoso, Adriana Coutinho de Azevedo Guimarães","doi":"10.5114/pm.2023.133570","DOIUrl":"10.5114/pm.2023.133570","url":null,"abstract":"<p><strong>Introduction: </strong>To analyse the possible association between menopausal symptoms (somatic-vegetative, psychological, and urogenital) and sexual function with the maintenance of the sexual activity of women in menopause.</p><p><strong>Material and methods: </strong>This cross-sectional study comprised 96 menopausal women aged 40-59 (52.88 ±4.05) years, who presented a positive score to the menopause rating scale (MRS) and had serum levels of follicle stimulating hormone ≥ 25 IU/ml. Participants who used hormone replacement therapy were excluded.</p><p><strong>Results: </strong>It was observed that participants who had an active sexual life had lower medians in the somatic-vegetative (p < 0.001) and psychological symptoms (p = 0.006), as well as in the general score (p = 0.001) at the MRS; in addition, they had better sexual function in 4 domains (p < 0.005): excitement, lubrication, orgasm, and pain, as well as in the total score of the female sexual function index questionnaire (p < 0.005). It was also found that, regardless of the type of menopause (surgical or natural), women who did not engage in sexual activity had a score of 5.651 points more in the MRS (p = 0.004), demonstrating that the practice of sexual activity predicts in 10.4% the variation in the symptom score.</p><p><strong>Conclusions: </strong>Menopausal women who maintain sexual activity had a lower score on the menopause symptom score and better sexual function compared to those who did not perform sexual activity.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"22 4","pages":"220-226"},"PeriodicalIF":1.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10793606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139493035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}