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Factors influencing surgical outcomes of laparoscopic myomectomy. A propensity-score matched analysis. 影响腹腔镜子宫肌瘤切除术效果的因素。倾向分数匹配分析。
IF 1.8
Przeglad Menopauzalny Pub Date : 2022-09-01 DOI: 10.5114/pm.2022.118970
Amedeo Catanese, Gabriele Siesto, Gaspare Cucinella, Vito Chiantera, Silvia Culmone, Antonio Schiattarella, Gloria Calagna, Domenico Vitobello
{"title":"Factors influencing surgical outcomes of laparoscopic myomectomy. A propensity-score matched analysis.","authors":"Amedeo Catanese,&nbsp;Gabriele Siesto,&nbsp;Gaspare Cucinella,&nbsp;Vito Chiantera,&nbsp;Silvia Culmone,&nbsp;Antonio Schiattarella,&nbsp;Gloria Calagna,&nbsp;Domenico Vitobello","doi":"10.5114/pm.2022.118970","DOIUrl":"https://doi.org/10.5114/pm.2022.118970","url":null,"abstract":"<p><strong>Introduction: </strong>To evaluate factors influencing surgical choice in performing uterine myomectomy by comparing laparoscopic and open approach surgery.</p><p><strong>Material and methods: </strong>We analyzed women undergoing uterine myomectomy in our hospital. Patients were divided into two groups: patients who underwent laparoscopic myomectomy (group A) and patients who underwent laparotomic myomectomy (group B). We matched 1 : 1 women in these two groups to compare the effects of the procedures on each outcome according to a propensity-matched score analysis.</p><p><strong>Results: </strong>460 myomectomies were performed in the study period: 361 cases by laparoscopy (group A) and 99 cases by laparotomy (group B). We found lower estimated intraoperative blood loss (200 ml group A vs. 300 ml group B, < 0.0001) and a smaller decrease in hemoglobin value on the first postoperative day (1.7 g/dl group A vs. 2.2 g/dl group B, < 0.0001) with the laparoscopic approach. The propensity score matching estimated that to obtain an equivalent outcome, we required an average of 2 myomas and an average diameter of 8 cm in laparoscopy and 10 cm in laparotomy. Moreover, the variables mostly associated with a laparotomic conversion were the presence of a myoma > 8 cm and association with the presence of more than 2 myomas.</p><p><strong>Conclusions: </strong>Despite some proposals from previous studies, there are no specific guidelines regarding the best surgical procedure for myomectomy. Our data confirm that the choice of surgical technique should consider the patient characteristics and the surgeon experience to reduce longer operating times and more significant blood loss.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":" ","pages":"149-156"},"PeriodicalIF":1.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/67/04/MR-21-47689.PMC9551366.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40321531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ectopic breast carcinoma. 异位乳腺癌。
IF 1.8
Przeglad Menopauzalny Pub Date : 2022-09-01 Epub Date: 2022-09-14 DOI: 10.5114/pm.2022.119528
Georgios-Ioannis Verras, Francesk Mulita, Levan Tchabashvili, Panagiotis Perdikaris, Ioannis Perdikaris, Maria-Ioanna Argentou
{"title":"Ectopic breast carcinoma.","authors":"Georgios-Ioannis Verras,&nbsp;Francesk Mulita,&nbsp;Levan Tchabashvili,&nbsp;Panagiotis Perdikaris,&nbsp;Ioannis Perdikaris,&nbsp;Maria-Ioanna Argentou","doi":"10.5114/pm.2022.119528","DOIUrl":"https://doi.org/10.5114/pm.2022.119528","url":null,"abstract":"<p><p>Carcinoma of the accessory breast tissue (CABT) is an extremely rare occurrence, representing 0.3% of all breast malignancies. A 65-year-old, postmenopausal woman was referred to our Breast Clinic complaining of a palpable, growing, and painful mass in her right axilla. Physical examination revealed a palpable tender mass, approximately 3 cm in size, visibly infiltrating the overlying skin area, while physical examination of the breast revealed no palpable lesions. Core biopsy of the mass was promptly scheduled, and the histological report came back positive for Nottingham Grade II NST invasive carcinoma of the breast. The patient underwent breast-conserving surgery and concomitant axillary lymph node dissection (ALND) for removal of the malignant mass. Care was taken to preserve the axillary vein and the long thoracic nerve. Closure of the axillary incision required mobilization of skin flaps to ensure optimal cosmetic results. Despite the ectopic breast tissue being a largely benign and infrequent occurrence, the breast surgeon must remain vigilant for the possibility of CABT development. At any rate, further epidemiological studies incorporating as many patients as possible are required in order to formulate recommendations on the management and prognosis of CABT. Until such guidelines exist, excision of the carcinoma, along with ALND performance, is a reasonable and justified approach to the surgical treatment of CABT.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":" ","pages":"218-221"},"PeriodicalIF":1.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fa/a3/MR-21-47798.PMC9551358.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40321533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The accuracy of the calcium-creatinine ratio in a spot urine sample for predicting preeclampsia. 预测先兆子痫的尿样钙-肌酐比值的准确性。
IF 1.8
Przeglad Menopauzalny Pub Date : 2022-09-01 Epub Date: 2022-09-23 DOI: 10.5114/pm.2022.119755
Ahmed M Hagras, Ibrahim A Abdelazim, Nareman Elhamamy
{"title":"The accuracy of the calcium-creatinine ratio in a spot urine sample for predicting preeclampsia.","authors":"Ahmed M Hagras,&nbsp;Ibrahim A Abdelazim,&nbsp;Nareman Elhamamy","doi":"10.5114/pm.2022.119755","DOIUrl":"https://doi.org/10.5114/pm.2022.119755","url":null,"abstract":"<p><strong>Introduction: </strong>Preeclampsia (PE) is a major cause of foetal and maternal morbidity. Currently, there is no reliable diagnostic test to predict PE.To evaluate the accuracy of the calcium-creatinine ratio (CCR) in a spot urine sample for the prediction of PE.</p><p><strong>Material and methods: </strong>Two hundred and forty-six pregnant women, attending the ante-natal clinic after 20 weeks` gestation were included in this study. After exclusion of pre-existing chronic renal disease affecting calcium and/or creatinine excretion, spot urine samples were taken from participants to detect the CCR. Participants were followed up until delivery; the women who developed PE were included in the PE group and compared with normotensive controls to evaluate the accuracy of CCR in a spot urine sample for the prediction of PE.</p><p><strong>Results: </strong>The gestational age at delivery and parity were significantly lower in the studied PE group compared to normotensive controls (36.1 ±4.3 weeks and 1.7 ±2.6 vs. 39.1 ±3.1 and 3.4 ±1.9; respectively), (<i>p</i> = 0.0002 and 0.0003; respectively). The body mass index (BMI) was significantly higher in the studied PE group compared to normotensive controls (29.3 ±4.1 vs. 24.6 ±3.3 kg/m<sup>2</sup>; respectively), (<i>p</i> = 0.01). The calcium-creatinine ratio ≤ 0.04 had 79.3% sensitivity, 96.3% specificity, 91.5% positive predictive value (PPV), 90.3% negative predictive value (NPV), and 90.7% overall accuracy in prediction of PE.</p><p><strong>Conclusions: </strong>The calcium-creatinine ratio ≤ 0.04 had 79.3% sensitivity, 96.3% specificity, 91.5% PPV, 90.3% NPV, and 90.7% overall accuracy in predicting PE. This study suggests the use of CCR in spot urine sample for screening and early detection of PE.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":" ","pages":"191-196"},"PeriodicalIF":1.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/24/MR-21-47864.PMC9551360.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40321627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Severity of climacteric symptomatology related to depression and sexual function in women from a private clinic. 私立诊所妇女更年期症状与抑郁和性功能的关系。
IF 1.8
Przeglad Menopauzalny Pub Date : 2022-09-01 Epub Date: 2022-09-28 DOI: 10.5114/pm.2022.119787
Alexandra Lińan-Bermudez, Jhony Chafloque-Chavesta, Pamela Leon Pastuso, Kiaraliz Huambachano Pinedo, John Barja-Ore
{"title":"Severity of climacteric symptomatology related to depression and sexual function in women from a private clinic.","authors":"Alexandra Lińan-Bermudez,&nbsp;Jhony Chafloque-Chavesta,&nbsp;Pamela Leon Pastuso,&nbsp;Kiaraliz Huambachano Pinedo,&nbsp;John Barja-Ore","doi":"10.5114/pm.2022.119787","DOIUrl":"https://doi.org/10.5114/pm.2022.119787","url":null,"abstract":"<p><strong>Introduction: </strong>The climacteric is a natural transition stage in women, in which hormonal changes occur that affect the physical and psychological well-being. Therefore, the objective was to determine the relationship of the severity of climacteric symptomatology with depression and sexual function in women.</p><p><strong>Materials and methods: </strong>It was a descriptive, cross-sectional study, with a sample of 60 women between 40 and 65 years old. The Female Sexual Function Questionnaire-2, the Menopause Rating Scale, and the Beck Depression Inventory were used.</p><p><strong>Results: </strong>The mean age of the women was 49.1 ±5.6 years. 21.7% of the women had severe depression, 28.3% moderate, and 50% mild/minimal. Changes in sleep habits (1.73 ±0.88) and in appetite (1.63 ±0.73) were the most severe manifestations. Difficulty sleeping (1.05 ±0.99), physical and mental fatigue (1.48 ±0.98), and vaginal sequelae (1.45 ±1.26) were the most serious complaints in the somatic, psychological, and urogenital domains, respectively. 60% presented severe sexual dysfunction regarding genital pain and 55% in vaginal penetration. Communicating sexual preferences to the partner was common in 75% of women. 88.3% had frequent sexual activity, but 63.3% had zero or low sexual satisfaction.</p><p><strong>Conclusions: </strong>Climacteric symptomatology is related to depression but not to women's sexual function.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":" ","pages":"165-169"},"PeriodicalIF":1.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8a/cf/MR-21-47886.PMC9551357.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40321624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The influence of body mass index and smoking on the age of onset of menopause in women in Bosnia and Herzegovina: a cross-sectional multicentric study. 体重指数和吸烟对波斯尼亚和黑塞哥维那妇女绝经年龄的影响:一项横断面多中心研究。
IF 1.8
Przeglad Menopauzalny Pub Date : 2022-09-01 DOI: 10.5114/pm.2022.119605
Mirzeta Rizvanović, Zumra Begić, Lejla Kamerić, Anis Cerovac, Selma Rizvanović, Merjem Begić, Dubravko Habek
{"title":"The influence of body mass index and smoking on the age of onset of menopause in women in Bosnia and Herzegovina: a cross-sectional multicentric study.","authors":"Mirzeta Rizvanović,&nbsp;Zumra Begić,&nbsp;Lejla Kamerić,&nbsp;Anis Cerovac,&nbsp;Selma Rizvanović,&nbsp;Merjem Begić,&nbsp;Dubravko Habek","doi":"10.5114/pm.2022.119605","DOIUrl":"https://doi.org/10.5114/pm.2022.119605","url":null,"abstract":"<p><strong>Introduction: </strong>Menopause is the last physiological menstrual period and is a complex process involving the following: endocrine, genitourinary, cardiovascular, and locomotor system, and it leads to vasomotor symptoms and psychological complaints. This study aims to investigate the influence of smoking and body mass index (BMI) as risk factors on the age of onset of menopause in women in Bosnia and Herzegovina.</p><p><strong>Material and methods: </strong>This study included 460 women in natural menopause. The study was conducted in 2 phases: interview and measurement of BMI. Each patient underwent an interview based on the questionnaire, following the verbal consent of the patient, who had previously been explained the nature of the research.</p><p><strong>Results: </strong>The age at which menopause occurs increases with the BMI increase, and it can be described by the regression equation: age = 0.096 × BMI + 45.7, which has statistical significance. The mean age of menopause occurrence in current smokers was lower (47.5 ±0.4 years) than in non-smokers (48.8 ±0.2 years) (<i>p</i> = 0.010).</p><p><strong>Conclusions: </strong>Our study confirmed the statistically significant correlation between smoking, BMI, and age of onset of menopause.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"21 3","pages":"180-184"},"PeriodicalIF":1.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c5/8f/MR-21-47810.PMC9551356.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10278532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of venous thromboembolism during the use of oral estrogen-progestogen hormone therapies in light of most recent research findings. 根据最近的研究结果,口服雌激素-孕激素治疗期间静脉血栓栓塞的风险。
IF 1.8
Przeglad Menopauzalny Pub Date : 2022-09-01 Epub Date: 2022-10-01 DOI: 10.5114/pm.2022.119861
Małgorzata Bińkowska, Artur Jakimiuk, Tomasz Paszkowski, Leszek Pawelczyk, Violetta Skrzypulec-Plinta
{"title":"Risk of venous thromboembolism during the use of oral estrogen-progestogen hormone therapies in light of most recent research findings.","authors":"Małgorzata Bińkowska,&nbsp;Artur Jakimiuk,&nbsp;Tomasz Paszkowski,&nbsp;Leszek Pawelczyk,&nbsp;Violetta Skrzypulec-Plinta","doi":"10.5114/pm.2022.119861","DOIUrl":"https://doi.org/10.5114/pm.2022.119861","url":null,"abstract":"<p><p>Two important studies evaluating the safety profile of oral estrogen-progestogen hormonal therapies conducted in standard clinical practice with respect to the venous system were recently published. A large prospective controlled cohort study (PRO-E2) based on the non-inferiority design has shown that the relative risk of developing venous thrombosis (VTE) in women using combined oral hormonal contraceptives (COHC) containing 17β-estradiol (1.5 mg) and nomegestrol acetate (2.5 mg) (E2/NOMAC) was not statistically different from that in users of COHC containing ethinylestradiol and levonorgestrel (EE/LNG). The aim of the recently presented study was to compare the risk of VTE in patients treated with a product for oral continuous combined menopausal hormone therapy containing 1 mg of 17ß-estradiol and 100 mg of micronized progesterone (1 mgE2/100 mgP4) with patients taking conjugated equine estrogens and medroxyprogesterone acetate (CEE/MPA). The study was based on an analysis of records retrieved from a US health insurance database, and was therefore concerned the real-life clinical practice. The hazard ratio of VTE when comparing 1 mgE2/100 mgP4 with CEE/MPA was 0.70 (95% CI: 0.53-0.92). The difference was found to be statistically significant (<i>p</i> < 0.05). The rewieved studies provide further evidence that the use of hormones bioidentical with endogenous steroids in oral contraception and menopausal hormone therapy creates an opportunity to combine high efficacy with a favorable safety profile.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":" ","pages":"197-199"},"PeriodicalIF":1.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/35/12/MR-21-47897.PMC9551365.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40321532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Sentinel lymph node mapping in endometrial cancer to reduce surgical morbidity: always, sometimes, or never. 子宫内膜癌前哨淋巴结定位以减少手术发病率:总是,有时,或从不。
IF 1.8
Przeglad Menopauzalny Pub Date : 2022-09-01 Epub Date: 2022-10-01 DOI: 10.5114/pm.2022.119862
Angelos Daniilidis, Chrysoula Margioula-Siarkou, Georgia Margioula-Siarkou, Panagiotis Papandreou, Alexios Papanikolaou, Konstantinos Dinas, Stamatios Petousis
{"title":"Sentinel lymph node mapping in endometrial cancer to reduce surgical morbidity: always, sometimes, or never.","authors":"Angelos Daniilidis,&nbsp;Chrysoula Margioula-Siarkou,&nbsp;Georgia Margioula-Siarkou,&nbsp;Panagiotis Papandreou,&nbsp;Alexios Papanikolaou,&nbsp;Konstantinos Dinas,&nbsp;Stamatios Petousis","doi":"10.5114/pm.2022.119862","DOIUrl":"https://doi.org/10.5114/pm.2022.119862","url":null,"abstract":"<p><strong>Introduction: </strong>Surgical staging of nodal status is of utmost significance to determine the stage of endometrial cancer and construct a targeted treatment plan. Systematic lymphadenectomy has for years been the procedure of choice for staging purposes, enabling thorough assessment of lymph nodes. Nevertheless, it is associated with increased morbidity and severe postoperative complications. In an attempt to avoid the disadvantages of lymphadenectomy, the use of sentinel lymph node (SLN) biopsy has been examined as an alternative staging procedure.The purpose of the present review is to summarize and provide up-to-date evidence about the role of SLN biopsy in the staging and management of endometrial cancer cases in the terms of optimal technique, efficacy, safety, and postoperative morbidity, as an alternative approach to regional lymphadenectomy.</p><p><strong>Material and methods: </strong>A thorough literature search was conducted in MEDLINE and SCOPUS to identify recent primary research and previous review articles that explore the use of SLN mapping as a staging procedure in patients with endometrial cancer.</p><p><strong>Results: </strong>There is increasing evidence that SLN mapping is efficient in identifying metastatic nodal disease without compromising oncological safety, achieving comparable or even superior detection rates to those of lymphadenectomy, when optimal technique and careful intraoperative nodal assessment are applied.</p><p><strong>Conclusions: </strong>Sentinel lymph node mapping can safely replace lymphadenectomy as an acceptable alternative staging method for endometrial cancer; however, future research might further strengthen this suggestion by resolving potential areas of doubt and debate, especially for high-risk endometrial cancer cases.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":" ","pages":"207-213"},"PeriodicalIF":1.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8f/b9/MR-21-47898.PMC9551362.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40321625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Morphological parameters of ovarian masses and accuracy of the risk of malignancy index in diagnosing ovarian malignancy. 卵巢肿块的形态学参数和恶性肿瘤风险指数诊断卵巢恶性肿瘤的准确性。
IF 2.5
Przeglad Menopauzalny Pub Date : 2022-06-01 Epub Date: 2022-05-24 DOI: 10.5114/pm.2022.116402
Akmaral S Adilgereyeva, Ibrahim A Abdelazim, Gulmira A Zhurabekova, Tamer E El-Ghazaly
{"title":"Morphological parameters of ovarian masses and accuracy of the risk of malignancy index in diagnosing ovarian malignancy.","authors":"Akmaral S Adilgereyeva, Ibrahim A Abdelazim, Gulmira A Zhurabekova, Tamer E El-Ghazaly","doi":"10.5114/pm.2022.116402","DOIUrl":"10.5114/pm.2022.116402","url":null,"abstract":"<p><strong>Introduction: </strong>To detect the morphological parameters of ovarian masses and the accuracy of the risk of mali-gnancy index (RMI) in diagnosing ovarian malignancy.</p><p><strong>Material and methods: </strong>264 women in 3 groups (reproductive, premenopausal, and postmenopausal) presented with ovarian masses and scheduled for surgery were included in this study. The participants' preoperative RMI was compared to the postoperative histology (gold standard) to detect the accuracy of RMI in diagnosing ovarian malignancy.</p><p><strong>Results: </strong>The incidence of malignant and benign ovarian tumours in the reproductive group was 9.1% and 90.9%, respectively, while it was 35.2% and 64.8%, respectively, in the premenopausal group, and 35.2%, and 64.8%, respectively, in the postmenopausal group. The incidence of malignant ovarian tumours was significantly higher in the premenopausal (35.2%) and postmenopausal (35.2%) groups compared to the reproductive group (9.1%), (<i>p</i> = 0.0008, and <i>p</i> = 0.0008, respectively).The receiver operating characteristic curve showed that RMI at cut-off value > 247.5 had 82.9% sensitivity, 100% specificity, 100% positive predictive value (PPV), and 98.1% negative predictive value (NPV) in diagnosing ovarian malignancy in the 3 studied groups (AUC 0.955, <i>p</i> < 0.001). There was significant positive correlation between the participants' age, and RMI (<i>p</i> = 0.001), and between participants' cancer antigen-125 (CA-125) and RMI (<i>p</i> < 0.0001) in the ovarian malignancy group.</p><p><strong>Conclusions: </strong>The multimodal RMI is an effective tool for primary evaluation of suspected ovarian masses. Risk malignancy index at cut-off value > 247.5 had the best performance (82.9% sensitivity, 100% specificity, 100% PPV, and 98.1% NPV) in diagnosing ovarian malignancy in the 3 studied groups. There was significant positive correlation between participants' age, and RMI, and between participants' CA-125 and RMI, in the studied malignant ovarian tumours.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"21 2","pages":"81-91"},"PeriodicalIF":2.5,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/a0/MR-21-47064.PMC9528815.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33490847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ghrelin, glucagon-like peptide-1, and peptide YY secretion in patients with and without weight regain during long-term follow-up after bariatric surgery: a cross-sectional study. 减肥手术后长期随访中体重恢复和未恢复患者胃饥饿素、胰高血糖素样肽-1和肽YY分泌的横断面研究
IF 1.8
Przeglad Menopauzalny Pub Date : 2022-06-01 Epub Date: 2022-06-08 DOI: 10.5114/pm.2022.116492
Charalampos Lampropoulos, Francesk Mulita, Theodoros Alexandrides, Dimitrios Kehagias, Dimitra Kalavrizioti, Konstantinos Albanopoulos, Neoklis Georgopoulos, Evangelos Papachristou, Ioannis Kehagias
{"title":"Ghrelin, glucagon-like peptide-1, and peptide YY secretion in patients with and without weight regain during long-term follow-up after bariatric surgery: a cross-sectional study.","authors":"Charalampos Lampropoulos,&nbsp;Francesk Mulita,&nbsp;Theodoros Alexandrides,&nbsp;Dimitrios Kehagias,&nbsp;Dimitra Kalavrizioti,&nbsp;Konstantinos Albanopoulos,&nbsp;Neoklis Georgopoulos,&nbsp;Evangelos Papachristou,&nbsp;Ioannis Kehagias","doi":"10.5114/pm.2022.116492","DOIUrl":"https://doi.org/10.5114/pm.2022.116492","url":null,"abstract":"<p><strong>Introduction: </strong>Weight loss after bariatric surgery is attributed, at least in part, to the altered gastrointestinal (GI) hormone secretion, which is thought to be responsible for a number of beneficial metabolic effects.</p><p><strong>Material and methods: </strong>We conducted a cross-sectional study. Twelve patients who underwent laparoscopic sleeve gastrectomy (SG) and 20 patients who underwent a variant of biliopancreatic diversion with Roux-en-Y gastric bypass and long limbs (BPD/RYGB-LL) were evaluated ≥ 7 years postoperatively. Ghrelin, glucagon-like peptide-1 (GLP-1), and peptide YY (PYY) secretion were compared between patients with successful weight loss maintenance (WM group) and patients with weight regain (WR group).</p><p><strong>Results: </strong>In both types of surgery, standard liquid mixed meal (SLMM) ingestion did not result in significant changes in fasting GI hormone levels. Fasting ghrelin levels did not differ between the WM group and the WR group in both types of surgery. In SG patients, SLMM ingestion elicited greater suppression of ghrelin levels in the WM group (p = 0.032). No difference in GLP-1 secretion was observed between the 2 groups of patients in both types of surgery. When patients were examined, regardless of the type of bariatric surgery they had undergone, postprandial PYY levels were lower in the WM group (p < 0.05), while fasting and postprandial PYY levels were correlated positively with an increase in body mass index (BMI) in the evaluation (Spearman's rho ≥ 0.395, p < 0.03).</p><p><strong>Conclusions: </strong>Our data do not support the hypothesis that long-term weight regain after bariatric surgery is associated with an unfavourable GI hormone secretion pattern.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"21 2","pages":"97-105"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a7/13/MR-21-47092.PMC9528819.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33490895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Factor affecting the activities of daily living among aging people during the COVID-19 pandemic - a structural equation modelling. COVID-19大流行期间影响老年人日常生活活动的因素——结构方程模型
IF 1.8
Przeglad Menopauzalny Pub Date : 2022-06-01 Epub Date: 2022-06-20 DOI: 10.5114/pm.2022.117183
Elham Nejadsadeghi, Shahab Papi, Maria Cheraghi, Samaneh Norouzi, Fatemeh Hosseini, Ghodratollah Shakeri Nejad
{"title":"Factor affecting the activities of daily living among aging people during the COVID-19 pandemic - a structural equation modelling.","authors":"Elham Nejadsadeghi,&nbsp;Shahab Papi,&nbsp;Maria Cheraghi,&nbsp;Samaneh Norouzi,&nbsp;Fatemeh Hosseini,&nbsp;Ghodratollah Shakeri Nejad","doi":"10.5114/pm.2022.117183","DOIUrl":"https://doi.org/10.5114/pm.2022.117183","url":null,"abstract":"<p><strong>Introduction: </strong>The activities of daily living (ADLs) are a set of basic skills necessary for self-care. The inability of elderly people to perform ADLs leads to dependence, insecure conditions, and poor quality of life. The COVID-19 pandemic has affected all aspects of the daily life of the elderly. This study aimed to determine the factors associated with ADLs among elderly people during the COVID-19 pandemic using structural equation modelling/path analysis.</p><p><strong>Material and methods: </strong>It was a descriptive-analytical study which had conducted on 487 elderly people who were selected randomly to participate in the study. Data collection tools included a demographic information questionnaire, an activities of daily living questionnaire, a knee pain and personal performance questionnaire Western Ontario and McMaster Universities Osteoarthritis (WOMAC), and the falls efficacy scale, which were completed by interview and self-report methods. SPSS-22 and AMOS software were used for data analysis.</p><p><strong>Results: </strong>Two structures of the fear of falling (FOF) and knee pain and personal performance questionnaire WOMAC had a significant role in explaining the ADL variance among the studied elderly people (<i>p</i> < 0.001, root mean square error of approximation = 0.063). These variables explained 64% of the ADL variance.</p><p><strong>Conclusions: </strong>The structures of this model (FOF and WOMAC) can be used as a reference framework to design effective interventions for improving ADLs among elderly people during the COVID-19 epidemic. It is also recommended that a multi-component program be provided, which includes exercise and psychological strategies for this population during the COVID-19 pandemic through online videos, distance health programs, etc.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"21 2","pages":"111-116"},"PeriodicalIF":1.8,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/06/fa/MR-21-47254.PMC9528812.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33490896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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