Przeglad MenopauzalnyPub Date : 2025-09-01Epub Date: 2025-10-04DOI: 10.5114/pm.2025.154679
Brandon E Guillen-Calle, John Barja-Ore, Dafne Gutierrez-Santos, Nicole Rodriguez-Clemente, Bertha Landa-Maturrano, Mayra Cerda-Sanchez
{"title":"Knowledge and beliefs about HIV/AIDS among perimenopausal women: Are there urban-rural differences?","authors":"Brandon E Guillen-Calle, John Barja-Ore, Dafne Gutierrez-Santos, Nicole Rodriguez-Clemente, Bertha Landa-Maturrano, Mayra Cerda-Sanchez","doi":"10.5114/pm.2025.154679","DOIUrl":"10.5114/pm.2025.154679","url":null,"abstract":"<p><strong>Introduction: </strong>HIV/AIDS remains a major public health issue, with social and cultural dimensions often underestimated. Middle-aged women, particularly in rural settings, represent a vulnerable and frequently overlooked population in prevention strategies, despite remaining sexually active during this life stage.</p><p><strong>Material and methods: </strong>A quantitative, cross-sectional, and analytical study was conducted using data from Peru's 2024 Demographic and Health Survey (ENDES). A total of 6,314 women aged 40 to 49 years with complete data were included: 4,176 from urban areas and 2,138 from rural areas. An additive index of adequate HIV/AIDS knowledge and beliefs was constructed (range: 0-9), along with sociodemographic and health information access variables. Statistical analysis was performed using Stata v17, and geographic visualization using RStudio.</p><p><strong>Results: </strong>Rural women reported lower exposure to HIV/AIDS information and less awareness of vertical transmission and asymptomatic HIV transmission (p < 0.001). Preventive beliefs were more frequent in urban areas, while misbeliefs, such as mosquito transmission, were more common in rural areas. Geographic analysis revealed a clear territorial gap, with higher index scores in urban zones. Nevertheless, some rural regions exhibited unexpectedly high scores.</p><p><strong>Discussion: </strong>Findings highlight informational and cultural disparities that hinder HIV prevention among rural women. These disparities underscore the need for tailored interventions that consider sociocultural and territorial specificities.</p><p><strong>Conclusions: </strong>Middle-aged women should be explicitly targeted by sexual health strategies. Regionalized interventions are essential to address territorial and sociocultural inequities in HIV/AIDS knowledge and beliefs.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"24 3","pages":"191-198"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12529530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2025-09-01Epub Date: 2025-10-04DOI: 10.5114/pm.2025.154674
Brandon E Guillen-Calle, John Barja-Ore, Nicole Rodriguez-Clemente, Alexandra Liñan-Bermudez, Zaida Zagaceta-Guevara
{"title":"Prevalence, intention to use, and factors associated with the decision to use contraceptives among Peruvian women aged 40 to 49 years.","authors":"Brandon E Guillen-Calle, John Barja-Ore, Nicole Rodriguez-Clemente, Alexandra Liñan-Bermudez, Zaida Zagaceta-Guevara","doi":"10.5114/pm.2025.154674","DOIUrl":"10.5114/pm.2025.154674","url":null,"abstract":"<p><strong>Introduction: </strong>The use of contraceptive methods (CM) in women aged 40 to 49 years is often underestimated, despite the risk of unplanned pregnancies. This study aimed to estimate the prevalence and associated factors of CM use among Peruvian women in this age group.</p><p><strong>Material and methods: </strong>An analytical, cross-sectional study was conducted based on secondary data from the 2023 Demographic and Family Health Survey (ENDES). Women aged 40 to 49 years who were neither pregnant nor menopausal were included. Sociodemographic, gynecologic-obstetric, and intimate partner violence variables were analyzed with adjustments for complex survey design.</p><p><strong>Results: </strong>The prevalence of CM use was 63.06%. The most commonly used methods were female sterilization (26.73%) and injectable contraceptives (15.46%). Contraceptive method use was higher among women aged 40-44 years, those who were married or cohabiting, and those with more children. Lower use was associated with the desire for more children, lack of knowledge about the ovulatory cycle, and a history of intimate partner violence. Among women not using CM, 54.22% expressed an intention to use them in the future, mainly favoring injectable methods or condoms. The most frequent reasons for non-use were infrequent sexual activity, perceived infertility, and not being in a relationship.</p><p><strong>Discussion: </strong>Contraceptive methods used in this group are influenced by personal, relational, and contextual factors. Violence and limited partner involvement negatively affect its adoption.</p><p><strong>Conclusions: </strong>It is necessary to strengthen personalized counseling strategies, reduce gender inequalities, and promote shared contraceptive responsibility among women of advanced reproductive age.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"24 3","pages":"163-169"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12529528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The association between chemerin expression in breast cancer cells and aggressiveness.","authors":"Levan Tchabashvili, Vasileios Leivaditis, Konstantina-Soultana Kitsou, Francesk Mulita, Helen Papadaki, Maria-Ioanna Argentou","doi":"10.5114/pm.2025.152474","DOIUrl":"10.5114/pm.2025.152474","url":null,"abstract":"<p><strong>Introduction: </strong>Breast cancer (BC), the most prevalent cancer amongst women globally, exhibits a complex relationship with obesity and its associated factors. Chemerin, an adipokine linked to both inflammatory and metabolic processes, has emerged as a potential player in tumor development and progression. This study delves into the potential role of chemerin in breast cancer by analyzing its expression patterns in tumor cells, fibroblasts, and adipocytes alongside corresponding clinico-pathological parameters.</p><p><strong>Material and methods: </strong>Encompassing 77 patients with invasive ductal carcinoma, the study revealed an interesting interplay between chemerin and disease characteristics.</p><p><strong>Results: </strong>While chemerin expression itself did not associate with established markers like BC stage, oestrogen receptor, or progesterone receptor status, its presence is elevated in patients with lymph node metastasis. Despite these insightful findings, the study acknowledges limitations inherent to its design. The absence of a healthy control group necessitates further controlled studies to solidify the observed associations. Additionally, external factors like diet and exercise, known to influence chemerin levels, were not accounted for, requiring more comprehensive patient history and examination data in future investigations.</p><p><strong>Conclusions: </strong>While chemerin expression did not correlate with traditional BC markers, its apparent associations with lymph node metastasis, c-ERB2 expression, and involvement within the tumour microenvironment warrant further exploration. This study paves the way for future research to elucidate the precise role of chemerin in BC development and progression, potentially paving the path for the development of novel diagnostic and prognostic tools.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"24 3","pages":"183-190"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12529533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2025-09-01Epub Date: 2025-10-04DOI: 10.5114/pm.2025.154684
Michele Palisciano, Matteo Terrinoni, Elisa Napoleoni, Federica Adinolfi, Dario Rossetti, Gian Carlo Di Renzo
{"title":"Benign serous cystadenofibroma with multimodal imaging suggestive of malignancy in a symptomatic postmenopausal patient.","authors":"Michele Palisciano, Matteo Terrinoni, Elisa Napoleoni, Federica Adinolfi, Dario Rossetti, Gian Carlo Di Renzo","doi":"10.5114/pm.2025.154684","DOIUrl":"10.5114/pm.2025.154684","url":null,"abstract":"<p><strong>Introduction: </strong>Adnexal masses in postmenopausal women often present a diagnostic challenge, especially when imaging reveals complex features such as solid components, papillary projections, and ascites. Accurate preoperative characterization is crucial to guide surgical management and avoid unnecessary extensive procedures. Multimodal imaging combined with serum tumor markers and validated risk prediction models such as the IOTA ADNEX (International Ovarian Tumor Analysis) model, enhances diagnostic accuracy in differentiating benign from malignant ovarian lesions.</p><p><strong>Case presentation: </strong>A 49-year-old postmenopausal woman presented to the Emergency Department with severe pelvic pain. Initial evaluation revealed a left adnexal mass with a total size of 13 cm, composed of an 8 cm cystic portion and a 5 cm solid component. Transvaginal ultrasound demonstrated three vascularized papillary projections. Computed tomography and magnetic resonance imaging confirmed the suspicious morphology and ascitic fluid. The preoperative risk of malignancy, calculated using the IOTA ADNEX model via freely accessible online tools, was 81.2%. Due to the severity of symptoms and high suspicion of malignancy, the patient underwent urgent diagnostic laparoscopy. Intraoperatively, the mass appeared partially torsed with external surface papillary excrescences. A left salpingo-oophorectomy was performed, and peritoneal and cystic fluids were collected for cytological analysis.</p><p><strong>Results: </strong>The final histopathology revealed a benign serous cystadenofibroma. Cytological evaluation of the fluids was negative for malignant cells. Postoperative recovery was uneventful.</p><p><strong>Conclusions: </strong>This case highlights the importance of comprehensive diagnostic evaluation in adnexal masses. Even when multimodal imaging and risk models suggest malignancy, benign lesions may mimic malignant features. Integrating clinical, radiologic, and intraoperative findings is essential to avoid overtreatment.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"24 3","pages":"221-224"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12529526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2025-09-01Epub Date: 2025-10-04DOI: 10.5114/pm.2025.154680
Aleksandra I Kamińska, Karolina Piecak, Paweł Milart, Piotr Czuczwar, Tomasz Paszkowski
{"title":"Tamoxifen treatment in breast cancer: diagnostic methods for endometrial changes.","authors":"Aleksandra I Kamińska, Karolina Piecak, Paweł Milart, Piotr Czuczwar, Tomasz Paszkowski","doi":"10.5114/pm.2025.154680","DOIUrl":"10.5114/pm.2025.154680","url":null,"abstract":"<p><p>The aim of the study was to review publications on the early, most accurate diagnosis of pathological changes in the endometrium, which occur during and after tamoxifen (TAM) therapy for breast cancer (BC). Accurate diagnosis of potential endometrial lesions is essential to make correct decisions regarding the necessity of adjuvant therapy with TAM. MEDLINE (http://www.ncbi.nlm.nih.gov/pubmed), EMBASE (http://www.embase.com) and Scopus (http://www.scopus.com) databases were searched using the following MeSH terms in titles and abstracts: (\"tamoxifen endometrial hyperplasia\" OR \"tamoxifen endometrial pathology\" OR \"endometrial pathology tamoxifen\"). No language restriction was used in the literature search. The search was limited to studies in humans. The results of an ultrasound investigation of the endometrium in asymptomatic BC patients receiving TAM should be interpreted with caution. An overdiagnosis of endometrial abnormalities, and the consequent unnecessary invasive diagnostic procedures could discourage some patients from continuing the adjuvant treatment with TAM, putting them at increased risk of recurrent BC. There is no evidence that patients receiving adjuvant TAM therapy could benefit from a screening program based on the ultrasound examination alone. Asymptomatic BC patients on adjuvant TAM-treatment should not be submitted routinely to ultrasound examination or biopsy, but encouraged to report any abnormal vaginal bleeding promptly.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"24 3","pages":"199-205"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12529531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2025-09-01Epub Date: 2025-10-04DOI: 10.5114/pm.2025.154673
Anna M Cybulska, Barbara Wesołowska, Aleksandra Derezińska, Przemysław Ustianowski, Kamila Rachubińska, Elżbieta Grochans, Daria Schneider-Matyka
{"title":"Associations between menopause and body image.","authors":"Anna M Cybulska, Barbara Wesołowska, Aleksandra Derezińska, Przemysław Ustianowski, Kamila Rachubińska, Elżbieta Grochans, Daria Schneider-Matyka","doi":"10.5114/pm.2025.154673","DOIUrl":"10.5114/pm.2025.154673","url":null,"abstract":"<p><strong>Introduction: </strong>Menopause significantly impacts a woman's life, marked by changes in sex hormone levels. Many perimenopausal women experience weight gain and other physical changes affecting their mental state and body image. The aim of the study was to evaluate the association between postmenopausal women's body image and the severity of menopausal symptoms.</p><p><strong>Material and methods: </strong>This survey-based study involved 271 postmenopausal female residents of the West Pomeranian Voivodeship. It was performed using the author questionnaire and Menopause Rating Scale, the Body Image Questionnaire by Alicja Głębocka, the Body Parts Satisfaction Scale and the Patient Health Questionnaire-9.</p><p><strong>Results: </strong>The participants had moderate menopause severity and were generally neutral about their appearance. No depressive symptoms were found in 31.37% of the women. Factors such as place of residence, education, onset of menopausal symptoms, and hormone replacement therapy influenced body image criticism scores. Education and employment status significantly affected depressive symptoms severity. The severity of menopausal symptoms was closely related to depressive symptoms and body image dissatisfaction.</p><p><strong>Conclusions: </strong>The severity of menopausal symptoms had a significant effect on body image and the level of depressive symptoms among the postmenopausal women.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"24 3","pages":"170-182"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12529535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2025-06-01Epub Date: 2025-06-16DOI: 10.5114/pm.2025.152126
Lidia Olszewska, Piotr Merks, Urszula Religioni, Ewa Jakubek, Grażyna Jarząbek-Bielecka, Monika Englert-Golon, Witold Kędzia, Katarzyna Plagens-Rotman
{"title":"Analysis of the reasons for removal of vascular ports in patients treated in chemotherapy and gynecological oncology departments - preliminary investigations.","authors":"Lidia Olszewska, Piotr Merks, Urszula Religioni, Ewa Jakubek, Grażyna Jarząbek-Bielecka, Monika Englert-Golon, Witold Kędzia, Katarzyna Plagens-Rotman","doi":"10.5114/pm.2025.152126","DOIUrl":"10.5114/pm.2025.152126","url":null,"abstract":"<p><strong>Introduction: </strong>The use of vascular ports in oncology patients for the administration of irritating and chemotherapeutic drugs clearly solves the problem of peripheral vascular damage caused by oncological drugs, and at the same time provides a comfortable way of treating patients in the long term. Although there are risks associated with the long-term maintenance of implanted ports, any risk factors for infection associated with an implantable intravenous port should be minimized.</p><p><strong>Material and methods: </strong>The main purpose of the study was to investigate the reasons for removal of vascular ports in patients undergoing systemic treatment at the wards of the University Clinical Hospital. Patients who had a vascular port implanted for the duration of their therapy were monitored for complications that had become the reason for removing the implants within 24 months of implantation.</p><p><strong>Results: </strong>The main reason for removing a vascular port was the conclusion of therapy (82.7%). The second reason for removing the ports was infection (13.5%), which, despite the use of rigorous procedures, could not be avoided due to the significant reduction in immunity in patients treated with oncological drugs.</p><p><strong>Conclusions: </strong>Despite their limitations in oncological treatment, ports have no alternatives, and thus further technological progress is essential. Education of staff working with patients with implants allows an increase in the benefits of therapy in the long run and significantly improves the quality of life of oncological patients. The education of patients and their families, as well as frequent re-training of staff, provides greater opportunities to minimize the side effects of therapy and reduce the number of adverse reactions related to infections.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"24 2","pages":"102-112"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An original exercise programme reduced stress urinary incontinence in pre- and postmenopausal women.","authors":"Agata Wojtczak, Bartosz Aniśko, Idzi Siatkowski, Małgorzata Wójcik","doi":"10.5114/pm.2025.152174","DOIUrl":"10.5114/pm.2025.152174","url":null,"abstract":"<p><strong>Introduction: </strong>Urinary incontinence has a negative impact on women's quality of life. One way to treat this may be to perform pelvic floor muscle exercises. This study evaluated the effects of an original exercise programme performed for 6 weeks.</p><p><strong>Material and methods: </strong>The study involved premenopausal (before-menopause group exercise - BMGE) and postmenopausal (post-menopause group exercise - PMGE) groups of women. Postural pattern, pelvic type were determined prior to exercise. A 1-day subpubic test was used to determine the amount of urine lost before and after exercise. The Kruskal-Wallis test, Dunn test and Wilcoxon test were used.</p><p><strong>Results: </strong>The results indicate that the original exercise programme had the effect of reducing urine loss in both groups, <i>p</i> < 0.0001. In the study groups, the number of deliveries had no effect on urinary incontinence, <i>p</i> = 0. 7021 (BMGE) and <i>p</i> = 0.4073 (PMGE), nor did route of delivery, <i>p</i> = 0.713 (BMGE) and <i>p</i> = 0.3613 (PMGE), pelvic type, <i>p</i> = 0.5079 (BMGE) and <i>p</i> = 0.4885 (PMGE), or postural pattern, <i>p</i> = 0.7331 (BMGE) and <i>p</i> = 0.7331 (PMGE).</p><p><strong>Conclusions: </strong>The original exercise programme reduced stress urinary incontinence in both groups women. Postural pattern, pelvic type, number of deliveries and route of delivery had no effect on the incidence of urinary incontinence in both groups of women.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"24 2","pages":"85-93"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2025-06-01Epub Date: 2025-06-23DOI: 10.5114/pm.2025.152241
Małgorzata Bińkowska, Tomasz Paszkowski, Violetta Skrzypulec-Plinta, Wojciech Zgliczyński
{"title":"Position paper of the expert panel of the Polish Society of Menopause and Andropause on the use of Oestrogel<sup>®</sup> in menopausal hormone therapy<sup />.","authors":"Małgorzata Bińkowska, Tomasz Paszkowski, Violetta Skrzypulec-Plinta, Wojciech Zgliczyński","doi":"10.5114/pm.2025.152241","DOIUrl":"10.5114/pm.2025.152241","url":null,"abstract":"<p><p>This position paper of the expert panel presents a comprehensive review of the efficacy, safety, and clinical application of bioidentical hormone replacement therapy (HRT), with particular focus on transdermal 17β-oestradiol gel (Oestrogel<sup>®</sup>). Bioidentical hormones - chemically identical to endogenous human hormones - are increasingly recognised as the preferred option in modern HRT, consistent with current international guidelines. Based on a review of randomised clinical trials and observational studies (sourced primarily from PubMed and Medline), transdermal oestradiol demonstrates a superior safety profile compared to oral formulations. Benefits include stable serum oestradiol levels without supraphysiological fluctuations; minimal impact on hepatic synthesis of procoagulant factors, triglycerides, hormone-binding proteins (SHBG, TBG, CBG), and inflammatory mediators (e.g. C-reactive protein); no increased risk of venous thromboembolism or ischaemic stroke; and the ability to use lower doses while maintaining efficacy. Additional advantages are a more physiological E2/E1 ratio, reduced inter-individual variability, and the option to monitor serum oestradiol levels. Oestrogel<sup>®</sup> supports dose flexibility and personalisation, allowing treatment to be tailored according to patient needs and guideline-based therapeutic schemes. When combined with micronised progesterone - the gold-standard progestogen for endometrial protection and the preferred option due to its favourable overall safety profile - this form of HRT offers a modern, well-tolerated, and individualised approach to the management of menopausal symptoms and osteoporosis prevention.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"24 2","pages":"131-136"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144801003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Przeglad MenopauzalnyPub Date : 2025-06-01Epub Date: 2025-06-12DOI: 10.5114/pm.2025.152085
Andrzej Jaworowski, Julia Jurga, Hubert Huras, Aleksander Gałaś, Gabriela Mierzwa, Aleksandra Stasiak, Magdalena Kołak
{"title":"Pregnancy outcomes following history- and ultrasound-indicated cervical cerclage: a 10-year retrospective cohort study from a tertiary center.","authors":"Andrzej Jaworowski, Julia Jurga, Hubert Huras, Aleksander Gałaś, Gabriela Mierzwa, Aleksandra Stasiak, Magdalena Kołak","doi":"10.5114/pm.2025.152085","DOIUrl":"10.5114/pm.2025.152085","url":null,"abstract":"<p><strong>Introduction: </strong>Cervical cerclage is a method used to prevent preterm delivery in pregnant women diagnosed with cervical insufficiency or a short cervix. This study aimed to compare pregnancy outcomes between cervical cerclage procedures performed due to history- and ultrasound-based indications.</p><p><strong>Material and methods: </strong>This retrospective cohort study was conducted at the Department of Obstetrics and Perinatology of the University Hospital in Cracow, Poland, a tertiary healthcare center. The study included women with singleton pregnancies who underwent cervical cerclage placement and subsequently gave birth in our department between 2013-2023.</p><p><strong>Results: </strong>Among 136 participants, 89 (65.4%) received history-indicated cerclage, and 47 (34.6%) underwent an ultrasound-indicated procedure. No statistically significant differences were found regarding miscarriage rates (3.4% vs. 2.1%) or preterm birth rates before 32 (9.0% vs. 14.9%), 34 (11.2% vs. 14.9%), and 37 (22.5% vs. 38.3%) gestational weeks between the history- and ultrasound-indicated groups (<i>p</i> ≥ 0.05). The median gestational age at delivery was 38.4 weeks for history-indicated cerclage and 38.3 weeks for ultrasound-indicated cerclage (<i>p</i> ≥ 0.05).</p><p><strong>Conclusions: </strong>Pregnancy outcomes following history-indicated cervical cerclage are comparable to those of ultrasound-indicated procedures. Consequently, emphasis should shift from predominantly performing prophylactic procedures to systematic cervical length screening and selective cerclage placement in cases of cervical shortening. Cervical cerclage remains an effective intervention for prolonging pregnancy in women with cervical insufficiency and a short cervix.</p>","PeriodicalId":55643,"journal":{"name":"Przeglad Menopauzalny","volume":"24 2","pages":"113-119"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144801004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}