Aging MalePub Date : 2021-12-01DOI: 10.1080/13685538.2021.1948992
Selvi Dinçer, Emre Uysal, Tanju Berber, Mustafa Halil Akboru
{"title":"The efficacy and tolerability of ultra-hypofractionated radiotherapy in low-intermediate risk prostate cancer patients: single center experience.","authors":"Selvi Dinçer, Emre Uysal, Tanju Berber, Mustafa Halil Akboru","doi":"10.1080/13685538.2021.1948992","DOIUrl":"https://doi.org/10.1080/13685538.2021.1948992","url":null,"abstract":"<p><strong>Background: </strong>We aimed to investigate the efficacy and tolerability of ultra-hypofractionated radiotherapy (UHRT) in the treatment of low and intermediate-risk prostate cancer patients.</p><p><strong>Methods: </strong>This retrospective study was conducted using data derived from 44 patients who underwent UHRT, and toxicity assessment and clinical response were investigated. Treatment consisted of 35-36.25 Gy in 5 fractions using stereotactic ablative radiotherapy (SABR) with the Linac-based delivery system.</p><p><strong>Results: </strong>The median duration of follow-up was 52 months (8-68 months) and the median age was 71.5 years (54-85 years). Twenty-seven patients were assigned as intermediate-risk, whereas 17 patients had low-risk. The 5-year overall survival rate was 87.8%, while the 5-year biochemical recurrence-free survival (bRFS) rate was 97.4%. Acute grade 3 genitourinary (GU) side effect was not observed in any patient, whereas acute gastrointestinal (GI) system grade 3 side effect was seen in 6.8% of the patients. Late grade 3 GU and GI side effects were seen in 4.6% and 6.8% of the patients, respectively. In patients with planning target volume (PTV) ≥85 ml, acute grade ≥2 GU side effects were more common (<i>p</i>=.034).</p><p><strong>Conclusion: </strong>Our data demonstrated that UHRT administered with volumetric arc therapy (VMAT) can be recommended for selected patients with low-intermediate risk prostate cancer. Further prospective, multicentric, controlled trials on larger series are warranted to reach more accurate conclusions.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13685538.2021.1948992","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39161869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aging MalePub Date : 2021-12-01DOI: 10.1080/13685538.2021.1948993
Jae Joon Park, Hyun Young Lee, Sung Ryul Shim, Sang Wook Lee, Kwang Taek Kim, Jae Heon Kim
{"title":"Prostate cancer specific mortality after 5α-reductase inhibitors medication in benign prostatic hyperplasia patients: systematic review and meta-analysis.","authors":"Jae Joon Park, Hyun Young Lee, Sung Ryul Shim, Sang Wook Lee, Kwang Taek Kim, Jae Heon Kim","doi":"10.1080/13685538.2021.1948993","DOIUrl":"https://doi.org/10.1080/13685538.2021.1948993","url":null,"abstract":"<p><strong>Background: </strong>Our study was conducted to investigate the effect of 5-ARI on the death rate from prostate cancer by means of an updated meta-analysis using related data.</p><p><strong>Methods: </strong>We did comprehensive literature searches using the PubMed, Embase, and Cochrane databases through July 2019. We evaluated the risk of bias in such studies using the ROBINS-I tool and analyzed deaths from cancer and deaths from all causes using HR.</p><p><strong>Results: </strong>The meta-analysis included 11 studies. The pooled overall HRs for cancer-specific deaths between 5-ARI treatment versus non-exposed groups were 0.937 (95% CI: 0.730, 1.201). In the subgroup moderator analysis, the number of patients and additional medication variables were significantly associated with deaths from all causes (<i>p</i> = 0.022 and <i>p</i> = 0.005, respectively). For detecting the publication bias or small-study effect in the included studies, we performed Begg and Mazumdar's correlation test (0.851 and 0.573) and Egger's regression coefficient test (0.035 and 0.245) and suggested that there was no evidence of publication bias or small-study effect in this meta-analysis.</p><p><strong>Conclusions: </strong>Our study indicated that exposure to 5-ARI had no close association between the overall death rate or cancer-specific deaths. To confirm these results, well-designed prospective studies with large samples are required.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39573959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aging MalePub Date : 2021-12-01DOI: 10.1080/13685538.2020.1786047
Wei Shen Tan, Anton Wong, Wasim Mahmalji, Asif Raza
{"title":"Is there still a role for digital rectal examination in the prostate cancer diagnostic pathway in the COVID-19 and post COVID-19 era?","authors":"Wei Shen Tan, Anton Wong, Wasim Mahmalji, Asif Raza","doi":"10.1080/13685538.2020.1786047","DOIUrl":"https://doi.org/10.1080/13685538.2020.1786047","url":null,"abstract":"<p><p>Digital rectal examination (DRE) is routinely performed as part of a urology clinical assessment in patients with a clinical suspicion of prostate cancer. An abnormal DRE or a raised prostate specific antigen (PSA) level are part of the criteria for primary care referral to secondary care due to a suspicion of prostate cancer. The current Coronavirus-19 (COVID-19) pandemic has resulted in the rapid adoption of virtual consultations in the form of telephone or video consultations making clinical examination difficult. In the case of prostate cancer diagnostic pathways, often clinicians now rely on PSA measurements and MRI, where radiological services are available, without the requirement for a DRE. We discuss the limited role DRE has in the modern prostate cancer diagnostic pathway due to the widespread adoption of MRI particularly in the COVID-19 era.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13685538.2020.1786047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39230666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and associated factors of metabolic syndrome in Chinese middle-aged and elderly population: a national cross-sectional study.","authors":"Yang Xiong, Yangchang Zhang, Fuxun Zhang, Changjing Wu, Feng Qin, Jiuhong Yuan","doi":"10.1080/13685538.2021.1998432","DOIUrl":"https://doi.org/10.1080/13685538.2021.1998432","url":null,"abstract":"<p><strong>Background: </strong>Currently, China has an increasingly aging population. However, the prevalence of metabolic syndrome (MetS) in this high-risk population for metabolic diseases remains unknown. This study investigates the age- and gender-specific prevalence and associated factors of MetS in the middle-aged and elderly Chinese population.</p><p><strong>Methods: </strong>Data were collected and subjected to descriptive statistics. Further, univariate logistic regression was used to evaluate the relevant factors, and then multivariate logistic regression was selected to construct the final model.</p><p><strong>Results: </strong>A total of 10,834 participants were included in the present study. The overall prevalence of MetS is 32.97% as defined by International Diabetes Federation (IDF) and 29.75% under National Cholesterol Education Program-The Adult Treatment Panel III (NCEP-ATP III) criteria. With aging, the prevalence of MetS descends in males while ascends in females. In the >70 years old group, the prevalence of MetS is three times higher in females than that in males (50.43% versus 16.03%). Across all age groups and sexes, the prevalence of MetS in urban areas is significantly higher than in rural areas. Besides, regardless of gender, the prevalence of MetS is the highest for those living in the north region (28.41% for males and 51.74% for females) and the lowest for those living in the southwest region (13.91% for males and 31.58% for females). Finally, an afternoon nap has been identified as a positively associated factor, while blood urea nitrogen (BUN) has been identified as a negatively associated factor (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>The prevalence of MetS varies in different age groups, sexes, living areas, and regions. An afternoon nap is positively associated with the prevalence of MetS, while BUN is negatively associated with MetS.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39602724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aging MalePub Date : 2021-12-01DOI: 10.1080/13685538.2021.1936482
Dursun Hakan Delibaş, Neslihan Eşkut, Birkan İlhan, Esin Erdoğan, Dilek Top Kartı, Özge Yılmaz Küsbeci, Gülistan Bahat
{"title":"Clarifying the relationship between sarcopenia and depression in geriatric outpatients.","authors":"Dursun Hakan Delibaş, Neslihan Eşkut, Birkan İlhan, Esin Erdoğan, Dilek Top Kartı, Özge Yılmaz Küsbeci, Gülistan Bahat","doi":"10.1080/13685538.2021.1936482","DOIUrl":"https://doi.org/10.1080/13685538.2021.1936482","url":null,"abstract":"<p><strong>Objective: </strong>We investigate the relationship between sarcopenia components and depression in geriatric outpatients, considering the effects of potential confounding factors.</p><p><strong>Methods: </strong>Adults ≥60 years of age were selected from outpatient clinics. Muscle strength was assessed using handgrip strength (HGS) measured using a hydraulic hand dynamometer and chair stand test (CSST). Physical performance was evaluated by usual gait speed (UGS), nutritional status, and frailty were screened by mini-nutritional assessment (MNA) questionnaire and FRAIL scale. Depression was diagnosed through a psychiatric interview and the administration of the Geriatric Depression Scale (GDS).</p><p><strong>Results: </strong>Participants with depression were similar to participants without depression regarding age (<i>p</i> = .055), education (<i>p</i> = .095), frailty (<i>p</i> = .857), and HGS scores (<i>p</i> = .053). The group with depression had longer CSST duration (<i>p</i> = .023), slower UGS (<i>p</i> = .027), and more malnutrition (<i>p</i> = .001). Multivariate regression analysis revealed that only the malnutrition was independently associated factor with depression after adjusting for confounding factors.</p><p><strong>Conclusions: </strong>Depression is associated with malnutrition and some components of sarcopenia in geriatric outpatients. Our results revealed that sarcopenia might be associated with depression through malnutrition. If malnutrition lasts for a long time, sarcopenia may become evident in the later stages of depression.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13685538.2021.1936482","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39252515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Low free testosterone level as a predictor of cardiovascular events in Japanese men with coronary risk factors.","authors":"Yuki Kato, Kazuyoshi Shigehara, Takahiro Inaba, Jiro Sakamoto, Masashi Iijima, Shohei Kawaguchi, Kouji Izumi, Yoshifumi Kadono, Mikio Namiki, Atsushi Mizokami","doi":"10.1080/13685538.2021.1920912","DOIUrl":"https://doi.org/10.1080/13685538.2021.1920912","url":null,"abstract":"<p><p><b>Aim:</b> We investigated whether low plasma free testosterone (FT) levels could predict cardiovascular events (CVE) in Japanese men with coronary risk factors.<b>Methods:</b> Male patients with classical coronary risk factors who had undergone serum FT testing were enrolled. New incidences of CVE were retrospectively investigated among all eligible participants based on their medical records.<b>Results:</b> Overall, 466 male outpatients with coronary risk factors without a previous history of CVE were identified. Throughout the follow-up period (median = 92 months), 126 CVE occurred. The Kaplan-Meier survival analysis according to the tertiles of plasma FT levels revealed that patients with the lowest FT tertile (<6.5 pg/mL) had a higher likelihood of developing CVE than those with the highest tertile (>9.3 pg/mL) (<i>p</i><.01). Multivariate analysis showed that increased frequency of CVE was observed with lower FT tertiles, independent of other coronary risk factors, with hazard ratios of 0.617 (95% CI, 0.389-0.976; <i>p</i>=.030) and 0.524 (95% CI, 0.309-0.887; <i>p</i>=.016) for the second and highest tertile relative to the lowest FT tertile, respectively.<b>Conclusion:</b> Among Japanese men with coronary risk factors, a lower FT level was a predictor for the development of cardiovascular diseases independent of other coronary risk factors and age.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13685538.2021.1920912","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38992937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aging MalePub Date : 2021-12-01DOI: 10.1080/13685538.2020.1817368
Caner Ediz, Serkan Akan, Hasan Huseyin Tavukcu, Muhammed Esad Kayhan, Omer Yilmaz
{"title":"Prognosis of primary or metachronous prostate cancer in multiple primary genitourinary cancers; a single center experience with long-term results.","authors":"Caner Ediz, Serkan Akan, Hasan Huseyin Tavukcu, Muhammed Esad Kayhan, Omer Yilmaz","doi":"10.1080/13685538.2020.1817368","DOIUrl":"https://doi.org/10.1080/13685538.2020.1817368","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to analyze the challenges, approaches and long-term results of primary or metachronous prostate cancer (PCa) in cases with multiple primary genitourinary cancers.</p><p><strong>Methodology: </strong>A total of 17 patients were included in the study. Patients with multiple primary genitourinary cancers were divided into two groups according to the diagnosis of primary or metachronous PCa as group 1 and group 2.</p><p><strong>Results: </strong>The median age of patients was similar in both groups. The median smoking status (pack-years) was higher in group 2 than group 1. The median prostate-specific antigen (PSA) level was higher in group 1 than group 2. The median follow-up time from primary to the metachronous tumour was higher in group 1 than group 2. The rate of recurrence in PCa was higher in group 1 than group 2. No statistically significant difference was observed in terms of patients' age, smoking status, PSA levels at diagnosis of PCa and biochemical recurrence or metastasis between the two groups (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>Primary PCa cases may progress more aggressively than metachronous PCa cases. Biochemical recurrence and metastasis may be less threatening in metachronous PCa cases than primary cases. Therefore, aggressive treatment can be avoided for metachronous PCa cases.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39267660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aging MalePub Date : 2021-12-01DOI: 10.1080/13685538.2021.1944085
Yaqiong Wang, Zili Wang, Xiaokun Gang, Guixia Wang
{"title":"Liquid biopsy in prostate cancer: current status and future challenges of clinical application.","authors":"Yaqiong Wang, Zili Wang, Xiaokun Gang, Guixia Wang","doi":"10.1080/13685538.2021.1944085","DOIUrl":"https://doi.org/10.1080/13685538.2021.1944085","url":null,"abstract":"<p><strong>Purpose: </strong>Liquid biopsy refers to the detection and analysis of the components from biological fluids non-invasively, including circulating tumor cells, nucleic acids, and extracellular vesicles (EVs). It is necessary to review the clinical value of liquid biopsy assays in PC and explore its potential application.</p><p><strong>Materials and methods: </strong>We systematically reviewed of PubMed was performed to identify relevant literature on potential clinical applications of circulating tumor cells, circulating nucleic acids, and EVs in prostate cancer (PC).</p><p><strong>Results: </strong>Liquid biopsy has emerged as a powerful tool to elucidate dynamic genomic, transcriptomic, and epigenomic tumor profiling in real-time. Here, the potential clinical applications of liquid biopsy include early detection, prognosis of survival, assessment of treatment response, and mechanisms of drug resistance in PC.</p><p><strong>Conclusions: </strong>Liquid biopsy provides great value in diagnosis, prognosis, and treatment response in PC. Characterization of liquid biopsy components provides benefits both to unravel underlying resistance mechanisms and to exploit novel clinically actionable targets in PC. In addition, we suggest that analysis of multiparametric liquid biopsies should be analyzed comprehensively, assisting in monitoring tumor characteristics in real-time, guiding therapeutic selection, and early therapeutic switching during disease progression.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39681075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aging MalePub Date : 2021-12-01DOI: 10.1080/13685538.2021.1911990
Abdullah Sisik, Ilyas Kudas, Fatih Basak, Mustafa Hasbahceci
{"title":"Is the increased incidence of pathologically proven acute appendicitis more likely seen in elderly patients? A retrospective cohort study.","authors":"Abdullah Sisik, Ilyas Kudas, Fatih Basak, Mustafa Hasbahceci","doi":"10.1080/13685538.2021.1911990","DOIUrl":"https://doi.org/10.1080/13685538.2021.1911990","url":null,"abstract":"<p><strong>Aim: </strong>Although appendicitis is a disease of the young, it has been speculated that its incidence has increased among the elderly people. In this study, it was aimed to evaluate annual changes of appendicitis seen in older patients (≥60 years) throughout a 10-year period.</p><p><strong>Methods: </strong>All adult patients who were surgically treated for acute appendicitis were retrospectively analyzed with respect to pathological analysis, gender, age and proportion of the patients aged 60 or over in an annual base. Variability in the mean age and proportion of the older patients aged 60 or over throughout the study years were regarded as the main outcomes.</p><p><strong>Results: </strong>There were 3296 patients with a mean age of 30.42 ± 12 years. Distribution of gender was similar (<i>p</i> = 0.636). There was a significant positive correlation in the mean age of the patients throughout the study years (<i>p</i> = 0.043). Stratification by the age of 60 yielded a significant increase in percent of the older patients, from 0.93% at 2007 to 4.28% at 2016 (<i>p</i> = 0.019).</p><p><strong>Conclusions: </strong>The mean age of the patients with acute appendicitis is going to increase. Therefore, it is expected that all surgeons are more likely to be confronted with elderly patients with appendicitis in the near-future.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13685538.2021.1911990","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38824928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Holmium laser enucleation <i>versus</i> bipolar transurethral enucleation for treating benign prostatic hyperplasia, which one is better?","authors":"Jinze Li, Dehong Cao, Yin Huang, Chunyang Meng, Lei Peng, Zhongyou Xia, Yunxiang Li, Qiang Wei","doi":"10.1080/13685538.2021.2014807","DOIUrl":"https://doi.org/10.1080/13685538.2021.2014807","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the overall efficacy and safety between holmium laser enucleation of the prostate (HoLEP) and bipolar transurethral enucleation of the prostate (B-TUEP) for the treatment of benign prostatic hyperplasia (BPH).</p><p><strong>Method: </strong>We systematically searched electronic databases (PubMed, Scopus, Web of Science, and Cochrane Library) to identify eligible comparative studies as of July 2021. The parameters including perioperative results, complications, and functional outcomes were evaluated. RevMan version 5.4 was used for the analysis.</p><p><strong>Results: </strong>A total of 10 studies involving 1725 patients were included. HoLEP had lower operative time (<i>p</i> = .03), shorter catheterization time (<i>p</i> = .007), lower bladder irrigation time (<i>p</i> = .01), and higher enucleation weight (<i>p</i> = .01) compared with B-TUEP. However, there were no significant differences between the techniques regarding the length of stay (LOS), hemoglobin drop, transfusion rates, and complications. Furthermore, no significant differences were also observed in postoperative functional outcomes at 1, 3, 6, 12, or 24 months.</p><p><strong>Conclusions: </strong>HoLEP has more advantages in perioperative parameters compared with B-TUEP, but no significant differences are found regarding functional outcomes and complications. Large-scale studies with long-term follow-up are required to compare the outcomes of these two techniques.</p>","PeriodicalId":55542,"journal":{"name":"Aging Male","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39715268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}