François Brezin, Kanetee Busiah, Clara Leroy, Elodie Fiot, Candace Bensignor, Cyril Amouroux, Marylène Caquard, Audrey Cartault, Sarah Castets, Clémence Delcour, Marie Devernay, Eva Feigerlova, Marie Hoarau, Béatrice Lebon-Labich, Anne-Sophie Lambert, Stéphanie Rouleau, Marie-Agathe Trouvin, Vanessa Vautier, Laetitia Martinerie
{"title":"Endocrine management of transgender adolescents: Expert consensus of the french society of pediatric endocrinology and diabetology working group.","authors":"François Brezin, Kanetee Busiah, Clara Leroy, Elodie Fiot, Candace Bensignor, Cyril Amouroux, Marylène Caquard, Audrey Cartault, Sarah Castets, Clémence Delcour, Marie Devernay, Eva Feigerlova, Marie Hoarau, Béatrice Lebon-Labich, Anne-Sophie Lambert, Stéphanie Rouleau, Marie-Agathe Trouvin, Vanessa Vautier, Laetitia Martinerie","doi":"10.1016/j.arcped.2024.08.003","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.08.003","url":null,"abstract":"<p><strong>Introduction: </strong>Requests for hormonal transition in minors are increasing. To date, there is no national recommendation to guide these practices in France. Therefore, the SFEDP (French Society of Pediatric Endocrinology and Diabetology) has commissioned a group of experts to draft the first national consensus on this topic.</p><p><strong>Method: </strong>Each chapter was prepared by one to three authors who conducted a literature review, and it was then reviewed and revised by the group as many times as necessary to achieve a consensus position. The final document was reviewed by a group of external experts.</p><p><strong>Results: </strong>A consensus position was reached regarding the multi-professional nature of support for trans youth, the prescription of molecules aimed at inhibiting endogenous hormone secretion, and the use of gender-affirming hormone therapies, as well as the importance of offering gamete preservation. Non-hormonal aspects of support and various considerations, including ethical ones, were also discussed.</p><p><strong>Conclusion: </strong>This work constitutes an initial set of recommendations for professionals involved in the hormonal transition of trans youth. Additional recommendations under the auspices of the French High Authority for Health would be worthy of being drafted, involving all relevant stakeholders to establish comprehensive official national guidelines that would secure the support and rights of these young individuals, especially those under 16 years old, as well as the professionals involved in their care.</p>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigating the effect of peer-led educational intervention on behaviors related to pubertal health and its determinants in high school girls of Genaveh, Iran: Application of social cognitive theory","authors":"Khadijeh Rezvani , Mohammad Hossein Kaveh , Leila Ghahramani , Abdolrahim Asadollahi","doi":"10.1016/j.arcped.2024.05.001","DOIUrl":"10.1016/j.arcped.2024.05.001","url":null,"abstract":"<div><div><em>Background</em> Empowering adolescents in the field of puberty health is one of the important goals of public health programs. The present study was carried out with the aim of determining the effect of peer-led training on puberty-related behavior and its determinants using social cognitive theory. <em>Methods</em>: A total of 245 teenage girls were randomly divided into two groups: the intervention group and the comparison group. The questionnaire measuring puberty-related behavior and its determinants was self-administered and completed before and 2 months after training in the two groups. One session for parents, four sessions for peer educators, and four sessions for participants were conducted for 1 month. <em>Results</em>: In the intervention group, unlike the comparison group, the mean scores of knowledge, outcome expectations, self-efficacy, self-control, social support, and behavior increased significantly after training (<em>p</em> <0.05). Based on regression analysis, outcome expectations and social support were the main determinants of puberty-related behavior (adjusted <em>R</em><sup>2</sup> = 0.464). <em>Conclusion</em>: The findings of this study support the effectiveness of the peer-led educational intervention based on social cognitive theory in the improvement of puberty-related behavior and its determinants, which can be used in the design of puberty-related health promotion programs. Further research to assess the longer-term outcomes and to examine other theories of behavior change are suggested.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"31 8","pages":"Pages 533-539"},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric teledermatology: Evaluation of a store-and-forward network in Ile-de-France from 2013 to 2022","authors":"Emmanuel Mahé , Béatrice Carton , Mariana Marcu-Marin , Stéphanie Muller , Fabienne Desjardins , Sarra Beizig , Véronique Hentgen , Marie-Aliette Dommergues , Yasmine Zerdani , Carla Hajj , Margot Common , Mandavi Rajguru , Adeline Rouby , Sylvie Nathanson","doi":"10.1016/j.arcped.2024.08.001","DOIUrl":"10.1016/j.arcped.2024.08.001","url":null,"abstract":"<div><h3>Background</h3><div>Teledermatology has been widely deployed over the past decade in France, becoming an indispensable tool in daily practice. Pediatric dermatology is a subspecialty of dermatology limited to a small number of specialists. In 2013, the Argenteuil Hospital developed a structured store-and-forward (SAF) service that is particularly well-suited for the field of pediatric dermatology. We report on our 10-year experience using the SAF approach in pediatric dermatology, focusing on the acceptability and efficiency of the service.</div></div><div><h3>Method</h3><div>All pediatric (<18 years) cases submitted to the SAF service from 2013 to 2022 were analyzed to evaluate SAF performance (refusals, response times, and information quality); patient demographics; pathologies (diagnostic certainty, types); and management.</div></div><div><h3>Results</h3><div>A total of 922 cases, from eight centers (six hospitals, two penitentiaries, and one health center) and 52 physicians, were analyzed. An increase in requests was noted over the years. No families refused to use the service. In 83 % and 94 % of cases, the quality of the photos and information was considered good or very good, respectively. The median response time was 1.5 h. The mean age of the children was 5 years (sex ratio: 1:1), with 26 % of cases involving newborns (<1 month). The median disease duration was 6 days (48 % <5 days). In 65 % of cases, the diagnosis was “certain,” whereas in 34 % of cases a “diagnostic hypothesis” was made. Examinations were recommended in 35 % of cases and treatment was proposed in 62 % of cases. Dermatological follow-up was proposed in 32 % of cases.</div></div><div><h3>Conclusion</h3><div>Our 10-year review of the SAF network showed that this pediatric teledermatology service has been accepted by parents and physicians. The information transmitted was of high quality, although additional clarification requests were sometimes required. The service enabled rapid responses in the majority of cases, including a wide variety of situations: one-quarter of cases involved newborns and 48 % of cases involved recently developed dermatoses (<5 days) requiring urgent management. This pediatric dermatology SAF-based tele-expertise service was therefore shown to be efficient and very well accepted, and is currently being deployed among private practitioners.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"31 8","pages":"Pages 500-507"},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the relationship between social media use, sharenting practices, and maternal psychological well-being","authors":"Betül Orhan Kılıç , Serhat Kılıç , Betul Ulukol","doi":"10.1016/j.arcped.2024.04.008","DOIUrl":"10.1016/j.arcped.2024.04.008","url":null,"abstract":"<div><h3>Background</h3><div>This study examined the correlation between social media usage, sharenting practices (sharing parenting-related content on social media), and psychological well-being among 130 mothers whose children visited Baskent University Hospital between April 2020 and January 2021.</div></div><div><h3>Methods</h3><div>The participants completed an online questionnaire that assessed their social media usage, sharenting practices on Instagram, as well as their levels of depression, life satisfaction, and psychological resilience. Additionally, the researchers created an Instagram account and followed the mothers’ social media activities.</div></div><div><h3>Results</h3><div>The findings revealed that Instagram was the most commonly used social media platform, with mothers using it an average of 5.8 times per day and spending an average of 75 min per day on the platform. Sharing privacy-violating photos of their children was positively correlated with the mothers’ own depressive symptoms (<em>r</em> = 0.285, <em>p</em> < 0.01) and negatively correlated with their life satisfaction (<em>r</em>=−0.274, <em>p</em> < 0.01). Similarly, sharing children's photos containing identifiable information was positively correlated with mothers’ depressive symptoms (<em>r</em> = 0.373, <em>p</em> < 0.01) and negatively correlated with their life satisfaction (<em>r</em>=−0.282, <em>p</em> = 0.001).</div></div><div><h3>Conclusion</h3><div>These findings indicate a significant relationship between social media usage, sharenting practices, and the psychological well-being of mothers. The study underscores the importance of raising awareness about the potential risks associated with social media use, particularly among mothers who engage in sharenting practices.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"31 8","pages":"Pages 519-526"},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Parental knowledge about respiratory syncytial virus and attitudes toward infant immunization with monoclonal antibodies in France","authors":"Gitte Lee Mortensen , Marie-Laure Charkaluk","doi":"10.1016/j.arcped.2024.07.003","DOIUrl":"10.1016/j.arcped.2024.07.003","url":null,"abstract":"<div><h3>Background and aim</h3><div>Respiratory syncytial virus (RSV) is a leading cause of hospitalization of infants with respiratory infections. A new immunization using monoclonal antibodies (mAbs) may offer protection against RSV infections. A study was conducted across eight countries to gain insight into parental awareness of RSV, their sources of child health information, and attitudes toward infant immunization against RSV using mAbs. This paper presents the findings from France.</div></div><div><h3>Methods</h3><div>In 2021, a survey was conducted in eight countries among expecting and current parents with children younger than 24 months of age. Eligible respondents included parents who were open to childhood immunizations, i.e., they had given or planned to give their children “all,” “most,” or “some” immunizations.</div></div><div><h3>Results</h3><div>In France, the survey respondents had high adoption rates for childhood immunizations. Key drivers behind these high rates were the desire to protect their children from severe diseases and adherence to mandatory immunizations, whereas concerns about safety were the main barriers.</div><div>While general practitioners and pediatricians were key sources of advice on child health, many parents also requested information about immunizations from health authorities and nurses. Sources of advice varied with parental age, gender, educational level, and income. The majority of parents had no knowledge about mAbs or passive immunization, and the overall awareness of RSV was low. When informed about RSV and mAbs, most parents held neutral to positive attitudes toward nirsevimab for their infants if recommended by a healthcare professional and/or included in the immunization program. These findings were further confirmed by the 60 %–80 % uptake rates of nirsevimab following the introduction in September 2023.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"31 8","pages":"Pages 484-492"},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehtap Eroglu , Nese Yaksi , Aysun Tekeli Taskomur , Gokce Yagmur Efendi , Didem Behice Oztop
{"title":"Effect of perceived social support, comorbid psychiatric disorders, and pregnancy complications on adaptation to pregnancy in adolescents: A comparison study from southeastern Turkey","authors":"Mehtap Eroglu , Nese Yaksi , Aysun Tekeli Taskomur , Gokce Yagmur Efendi , Didem Behice Oztop","doi":"10.1016/j.arcped.2024.08.002","DOIUrl":"10.1016/j.arcped.2024.08.002","url":null,"abstract":"<div><h3>Objective</h3><div>Adolescent pregnancies are categorized as high risk due to their adverse obstetric and neonatal outcomes. The aim of our study was to investigate the well-being of pregnant adolescents by assessing pregnancy complications, depression, anxiety, social support, and adaptation to pregnancy.</div></div><div><h3>Methods</h3><div>Pregnant adolescents who presented to the Obstetrics and Gynecology Outpatient Clinic of Hatay Training and Research Hospital between July 2022 and January 2023 were included in the study. Pregnant adults were also included as a control group during the same period. All participants were assessed using the Beck Depression Inventory, Multidimensional Scale of Perceived Social Support, Perinatal Anxiety Screening Scale, and Prenatal Self-Evaluation Questionnaire.</div></div><div><h3>Results</h3><div>A total of 61 pregnant adolescents were enrolled in the study and were compared with 116 adults. Our findings indicate that pregnant adolescents tend to exhibit a higher rate of pregnancy complications in comparison with pregnant adults, with complication rates of 14.8 % and 6.1 %, respectively (<em>p</em> = 0.057). The presence of complications had a negative impact on the acceptance of pregnancy in adolescents unlike in adults (<em>p</em> = 0.022). The relationship of pregnant adolescents with their partners was negatively affected by pregnancy complications (<em>p</em> = 0.046). Perceived social support (especially that of a partner) significantly reduced depression and anxiety scores in pregnant adolescents during the prenatal period (<em>p</em> = 0.002)</div></div><div><h3>Conclusion</h3><div>Adolescent pregnancies have negative psychiatric consequences even in traditional societies where child marriage is accepted. Future studies should consider variables that may reduce the impact of sociocultural factors on adolescent pregnancy.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"31 8","pages":"Pages 513-518"},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maeva Jego , Camille De Lapeyrière , Mohamed Belhachemi , Didier Théry , Aurélie Janczewski
{"title":"Managing child abuse or suspected child abuse in primary care: Results from a qualitative study of general practitioners trained in detecting child abuse","authors":"Maeva Jego , Camille De Lapeyrière , Mohamed Belhachemi , Didier Théry , Aurélie Janczewski","doi":"10.1016/j.arcped.2024.07.006","DOIUrl":"10.1016/j.arcped.2024.07.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Identifying and alerting suspected child abuse enables its investigation and management. In France, anyone can report the situation to child services when child abuse is suspected. However, the number of reports of concern received from physicians is low, and lack of knowledge is a frequent obstacle. This study aimed to explore the practices of trained general practitioners (GPs) regarding the identification and management of suspected child abuse.</div></div><div><h3>Method</h3><div>We led a qualitative study from February to November 2021 based on a grounded theory approach. We conducted semi-structured interviews with GPs working in the south of France who had received training in identifying child abuse. We performed an inductive analysis using NVivo software.</div></div><div><h3>Results</h3><div>We interviewed 10 GPs (data saturation with seventh GP). Despite the training, obstacles seemed to persist, such as apprehension of the parents’ reaction, the technical difficulties of the process, and the lack of feedback after making a report. Being accompanied by a professional who can be directly contacted would facilitate the communication of worrying information. Without direct links to a single referent, doctors would prefer alternative ways of referring their patients to organizations they were familiar with.</div></div><div><h3>Discussion and conclusion</h3><div>GPs expressed a need for easy access to childcare professionals to support them in the decision to file a report of suspected child abuse. A multidisciplinary approach and a dedicated point of contact seemed to help the process. Nominating a child protection referent doctor per department and creating specific units in hospitals for children at risk would help GPs get effectual contacts for reporting worrying information and better care for children at risk of abuse.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"31 8","pages":"Pages 508-512"},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gilles Cambonie, Florence Masson, Renaud Mesnage, Arthur Gavotto
{"title":"Management of patent ductus arteriosus in preterm infants: Abundant literature, low certainty of evidence for clinicians","authors":"Gilles Cambonie, Florence Masson, Renaud Mesnage, Arthur Gavotto","doi":"10.1016/j.arcped.2024.10.001","DOIUrl":"10.1016/j.arcped.2024.10.001","url":null,"abstract":"<div><div>Management of patent ductus arteriosus (PDA) in preterm newborns has been debated extensively for more than six decades. Some authors affirm that PDA is only an innocent mirror of infant immaturity, without specific health consequences. They also underline the futility, even danger, of treating it. Others are concerned about the hemodynamic effects of this left-right shunt, resulting in high pulmonary blood flow and low systemic output, which can contribute to the occurrence of severe morbidities — including pulmonary hemorrhage, intraventricular hemorrhage, bronchopulmonary dysplasia and necrotizing enterocolitis —and may increase the risk of death. Many management strategies have been described, ranging from expectant management to nontargeted prophylaxis, but there is currently no consensus about who to treat, when, and how.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"31 8","pages":"Pages 473-479"},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lelia Abad, Denise Antona, Candice Roudier, Vincent Auvigne, Jonathan Bastard, Clara Blondel, Julien Durand, Myriam Fayad, Cécile Forgeot, Julie Figoni, Alexandra Mailles, Frédéric Moisan, Guillaume Spaccaferri, Didier Che, Daniel Levy-Bruhl, Marion Hulin
{"title":"Keeping schools open during the emergence of the COVID-19 alpha variant: Impact on the circulation of SARS-CoV-2 among children during the 2020–2021 school year","authors":"Lelia Abad, Denise Antona, Candice Roudier, Vincent Auvigne, Jonathan Bastard, Clara Blondel, Julien Durand, Myriam Fayad, Cécile Forgeot, Julie Figoni, Alexandra Mailles, Frédéric Moisan, Guillaume Spaccaferri, Didier Che, Daniel Levy-Bruhl, Marion Hulin","doi":"10.1016/j.arcped.2024.07.005","DOIUrl":"10.1016/j.arcped.2024.07.005","url":null,"abstract":"<div><h3>Background</h3><div>During 2020–2021, in the context of increasing SARS-CoV-2 transmission in the general population, French authorities made the decision to keep schools open and set up massive screening campaigns for students. Here, we describe the impact of this strategy on the circulation of SARS-COV-2 among children and adolescents during this period.</div></div><div><h3>Methods</h3><div>We analyzed SARS-COV-2 surveillance data provided by the French National Public Health Agency for the 2020–2021 school year along with the results of school-based screening campaigns implemented by the Ministry of National Education.</div></div><div><h3>Results</h3><div>The proportion of 0–17-year-olds among confirmed cases and tested individuals increased throughout the school year, with children and adolescents reaching a maximum of 24 % of confirmed cases in 2021 week (W) 22. During the first semester of 2021 (W3–W22), >2.6 million tests were performed in schools, with a positivity rate of 0.32 % among students. Considering only symptomatic cases, higher incidence rates occurred among children and adolescents during the 2021 wave from W9 to W17 compared with that in 2020 from W40 to W48. The incidence rate did not significantly change following the school closure periods.</div></div><div><h3>Conclusion</h3><div>The higher contribution of children and adolescents to viral circulation during the 2020–2021 school year seems more related to the emergence of the alpha variant than to France's decision to keep schools open. Considering the negative impact of school closures on children's mental health, these results support the decision to keep schools open when accompanied by appropriate control measures.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"31 8","pages":"Pages 493-499"},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Stocker , Laura Fillistorf , Giorgia Carra , Eric Giannoni
{"title":"Early detection of neonatal sepsis and reduction of overall antibiotic exposure: Towards precision medicine","authors":"Martin Stocker , Laura Fillistorf , Giorgia Carra , Eric Giannoni","doi":"10.1016/j.arcped.2024.10.003","DOIUrl":"10.1016/j.arcped.2024.10.003","url":null,"abstract":"<div><div>Infections claim the lives of over half a million newborns annually and expose survivors to the risk of lifelong disability. The challenge to clinicians is to identify newborns with invasive infections rapidly, promptly initiate antimicrobial treatment, and take measures to prevent and treat organ dysfunction. Moreover, excessive antibiotic use is a global public health problem. Despite considerable research on clinical and laboratory markers of neonatal sepsis, the effective translation into clinical practice remains limited. There is no single clinical or laboratory marker, nor any combination of markers that definitively confirms or rules out neonatal sepsis. The interpretation of these markers should take into account their diagnostic value for a given patient, along with their added value to the clinical decision-making process. The digitalization of health care systems, combined with increased computational power and advances in machine learning, offers the possibility of developing accurate predictive algorithms for early detection of neonatal sepsis.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"31 8","pages":"Pages 480-483"},"PeriodicalIF":1.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}