Archives De Pediatrie最新文献

筛选
英文 中文
Neonatal screening: A public health success and the ethical dilemmas it can pose. 新生儿筛查:公共卫生的成功及其可能带来的伦理困境。
IF 1.3 4区 医学
Archives De Pediatrie Pub Date : 2024-09-12 DOI: 10.1016/j.arcped.2024.07.002
Brigitte Chabrol
{"title":"Neonatal screening: A public health success and the ethical dilemmas it can pose.","authors":"Brigitte Chabrol","doi":"10.1016/j.arcped.2024.07.002","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.07.002","url":null,"abstract":"","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life of chronically ill children and adolescents: a cross-sectional study. 慢性病儿童和青少年的生活质量:一项横断面研究。
IF 1.3 4区 医学
Archives De Pediatrie Pub Date : 2024-09-12 DOI: 10.1016/j.arcped.2024.04.007
Pauline Perreard, Sarah Castets, Karine Aouchiche, Delphine Bernoux, Daniele Bruno, Mathilde Cailliez, Stéphanie Clave, Marie-Edith Coste, Cécile De Leusse, Pauline Duvant, Florentine Garaix, Laetitia Gauche, Emeline Marquant, Céline Roman, Bertrand Roquelaure, Caroline Rousset Rouvière, Julia Vergier, Michel Tsimaratos, Julie Berbis, Alexandre Fabre, Rachel Reynaud
{"title":"Quality of life of chronically ill children and adolescents: a cross-sectional study.","authors":"Pauline Perreard, Sarah Castets, Karine Aouchiche, Delphine Bernoux, Daniele Bruno, Mathilde Cailliez, Stéphanie Clave, Marie-Edith Coste, Cécile De Leusse, Pauline Duvant, Florentine Garaix, Laetitia Gauche, Emeline Marquant, Céline Roman, Bertrand Roquelaure, Caroline Rousset Rouvière, Julia Vergier, Michel Tsimaratos, Julie Berbis, Alexandre Fabre, Rachel Reynaud","doi":"10.1016/j.arcped.2024.04.007","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.04.007","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to describe the quality of life (QoL) of children with a chronic illness treated in a tertiary multidisciplinary pediatric department in comparison with the general population.</p><p><strong>Study design: </strong>A cross-sectional study was conducted in the tertiary multidisciplinary (nephrology, hepatogastroenterology, endocrinology, diabetology, transplantation) pediatric department of Timone Hospital in Marseille, France. Patients 8-17 years of age with a chronic disease were included during regular follow-up appointments. Medical and sociodemographic variables were obtained from medical records. Self-reported QoL was assessed using the VSPA (Vécu et Santé Perçu de l'Adolescent) questionnaire and parent-reported QoL was assessed using the VSPA questionnaire for parents.</p><p><strong>Results: </strong>A total of 244 patients were included. Overall QoL did not differ significantly from that of the general population. Adolescent patients' self-reported QoL scores were lower than those of the general population in the domains of physical health and leisure, and parents reported QoL scores for adolescent patients lower than those of the general population for self-esteem and physical health. Adolescents' self-reported QoL scores were higher than in the general population for relationships with parents, healthcare professionals, and teachers as well as for school achievement. Parents also reported higher QoL scores in these areas for their children.</p><p><strong>Conclusion: </strong>Children and adolescents with a variety of chronic diseases had similar overall QoL scores to the general population but with different QoL profiles; their scores in some domains were higher than those of the general population.</p>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new nonsense pathogenic variant in exon 1 of PHOX2B leads to the diagnosis of congenital central hypoventilation syndrome with intra-familial variability. PHOX2B 外显子 1 中的一个新的无义致病变异导致先天性中枢通气不足综合征的诊断,且具有家族内变异性。
IF 1.3 4区 医学
Archives De Pediatrie Pub Date : 2024-09-10 DOI: 10.1016/j.arcped.2024.06.003
Morgane Pelleter, Charlène Desaintjean, Romane Gyapay, Bruno Massenavette, Florent Baudin, Nathalie Couque, Renaud Tamisier, Benjamin Dudoignon, Patricia Franco, Antoine Mougenel-Chantereau, Laurianne Coutier
{"title":"A new nonsense pathogenic variant in exon 1 of PHOX2B leads to the diagnosis of congenital central hypoventilation syndrome with intra-familial variability.","authors":"Morgane Pelleter, Charlène Desaintjean, Romane Gyapay, Bruno Massenavette, Florent Baudin, Nathalie Couque, Renaud Tamisier, Benjamin Dudoignon, Patricia Franco, Antoine Mougenel-Chantereau, Laurianne Coutier","doi":"10.1016/j.arcped.2024.06.003","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.06.003","url":null,"abstract":"<p><p>Congenital central hypoventilation syndrome (CCHS) is a rare genetic disorder of the autonomic nervous system resulting in decreased brain sensitivity to hypercapnia and hypoxia characterized by a genetic abnormality in the pair-like homeobox 2B (PHOX2B) gene. Most patients have a heterozygous expansion of the polyalanine repeat in exon 3 (PARM), while 10 % of patients have non-PARM (NPARM) mutations that can span the entire gene. The majority of pathogenic variants are de novo, but variants with incomplete penetrance can be identified in the heterozygous state. In the present report, CCHS was diagnosed in a symptomatic 3-month-old infant with neonatal respiratory distress. Genetic analysis revealed a new mutation in exon 1 of the PHOX2B gene - p.Ser28* (c.83C>G) - which was further identified in two family members, one minimally symptomatic and one asymptomatic. The identification of this new mutation supports the importance of sequencing the entire gene even when the classic PARM mutation is not found and highlights the phenotypic variability of CCHS.</p>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics and predictors of outcome in children with severe acute bronchiolitis: A 10-yearexperience. 严重急性支气管炎患儿的特征和预后因素:10年的经验。
IF 1.3 4区 医学
Archives De Pediatrie Pub Date : 2024-09-10 DOI: 10.1016/j.arcped.2024.06.002
Samia Hamouda, Safa Khatrouch, Aida Borgi, Ahmed Hajji, Hanen Smaoui, Najla Ben Jaballah, Fatma Khalsi, Khadija Boussetta
{"title":"Characteristics and predictors of outcome in children with severe acute bronchiolitis: A 10-yearexperience.","authors":"Samia Hamouda, Safa Khatrouch, Aida Borgi, Ahmed Hajji, Hanen Smaoui, Najla Ben Jaballah, Fatma Khalsi, Khadija Boussetta","doi":"10.1016/j.arcped.2024.06.002","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.06.002","url":null,"abstract":"<p><strong>Background: </strong>Severe acute bronchiolitis (SAB) can be life-threatening for infants and may be responsible for the congestion of intensive care units (ICU) during epidemics. We aimed to study the clinical and paraclinical characteristics of patients with SAB requiring a transfer to the ICU in order to examine their outcomes and to identify the predictors of a stay of ≥7 days and/or death.</p><p><strong>Methods: </strong>This was a cross-sectional retrospective study including infants aged ≤12 months transferred to the ICU for their first episode of SAB between 1 January 2010 and 31 December 2019.</p><p><strong>Results: </strong>We collected data on 380 patients with a median age of 1.75 months. They had a history of prematurity (20.53 %), low birth weight (18.68 %), parental atopy (12.89 %), and comorbidity (7.37 %, mainly congenital heart disease [5 %]). The leading cause of transfer was hypoxemia and increased oxygen requirements (49.73 %). The patients required mechanical ventilation (MV) in 63.42 % of the cases and noninvasive ventilation (NIV) in 67.63 %. NIV has supplanted MV over the years. Its use has increased from 40.4 % in 2010 to 96 % in 2019 compared with 83.84 % and 42 % for MV. A total of 14 (3.68 %) patients died. The independent predictors of a stay of ≥7 days and/or death were young age ≤2 months (p = 0.002), failure to thrive (p = 0.006), apnea (p = 0.045), dehydration (p = 0.018), the presence of biological inflammatory reaction (p = 0.002), isolation of respiratory syncytial virus (p < 0.001), and bacterial coinfection (p = 0.013).NIV was a protective factor (p < 0.001). A severity score ranging from 0 to 17 was established with an optimal cut-off value of 5 points.</p><p><strong>Conclusion: </strong>Specific caution is needed in patients with these severity predictors. The generalization ofNIV in general pediatrics departments would improve SAB management and reduce transfers to the ICU.</p>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parental knowledge about respiratory syncytial virus and attitudes toward infant immunization with monoclonal antibodies in France. 法国家长对呼吸道合胞病毒的了解以及对婴儿接种单克隆抗体的态度。
IF 1.3 4区 医学
Archives De Pediatrie Pub Date : 2024-09-10 DOI: 10.1016/j.arcped.2024.07.003
Gitte Lee Mortensen, Marie-Laure Charkaluk
{"title":"Parental knowledge about respiratory syncytial virus and attitudes toward infant immunization with monoclonal antibodies in France.","authors":"Gitte Lee Mortensen, Marie-Laure Charkaluk","doi":"10.1016/j.arcped.2024.07.003","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.07.003","url":null,"abstract":"<p><strong>Background and aim: </strong>Respiratory syncytial virus (RSV) is a leading cause of hospitalization of infants with respiratory infections. A new immunization using monoclonal antibodies (mAbs) may offer protection against RSV infections. A study was conducted across eight countries to gain insight into parental awareness of RSV, their sources of child health information, and attitudes toward infant immunization against RSV using mAbs. This paper presents the findings from France.</p><p><strong>Methods: </strong>In 2021, a survey was conducted in eight countries among expecting and current parents with children younger than 24 months of age. Eligible respondents included parents who were open to childhood immunizations, i.e., they had given or planned to give their children \"all,\" \"most,\" or \"some\" immunizations.</p><p><strong>Results: </strong>In France, the survey respondents had high adoption rates for childhood immunizations. Key drivers behind these high rates were the desire to protect their children from severe diseases and adherence to mandatory immunizations, whereas concerns about safety were the main barriers. While general practitioners and pediatricians were key sources of advice on child health, many parents also requested information about immunizations from health authorities and nurses. Sources of advice varied with parental age, gender, educational level, and income. The majority of parents had no knowledge about mAbs or passive immunization, and the overall awareness of RSV was low. When informed about RSV and mAbs, most parents held neutral to positive attitudes toward nirsevimab for their infants if recommended by a healthcare professional and/or included in the immunization program. These findings were further confirmed by the 60 %-80 % uptake rates of nirsevimab following the introduction in September 2023.</p>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between chronotype and mental toughness in adolescents: Is resilience a mediator? 青少年的时间型与心理韧性之间的关系:复原力是中介吗?
IF 1.3 4区 医学
Archives De Pediatrie Pub Date : 2024-09-10 DOI: 10.1016/j.arcped.2024.06.001
Esra Uslu, Hülya Çelik Özdemir, Türkan Peşkirci
{"title":"The relationship between chronotype and mental toughness in adolescents: Is resilience a mediator?","authors":"Esra Uslu, Hülya Çelik Özdemir, Türkan Peşkirci","doi":"10.1016/j.arcped.2024.06.001","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.06.001","url":null,"abstract":"<p><strong>Objective: </strong>This study was designed to examine the mediator role of resilience in the relationship between chronotype and mental toughness in adolescents.</p><p><strong>Methods: </strong>The descriptive correlational study was completed with 342 high school students from one school in Türkiye (mean age 17.25±1.11 years). Data were collected with the Morningness-Eveningness Scale for Children, Child and Youth Resilience Measure, and Mental Toughness Scale for Adolescents. Hierarchical regression analyses with PROCESS Model 4 were used to evaluate the mediator effect.</p><p><strong>Results: </strong>It was observed that the morning chronotype tendency increased resilience (p < 0.001) mental toughness (p < 0.001). Higher resilience led to increased mental toughness. When the mediation effect was examined, resilience was a full mediator in the relationship between chronotype characteristics and mental toughness (β=0.396; p = 0.000).</p><p><strong>Conclusions: </strong>According to these results, a morning chronotype tendency in adolescents increases their resilience and, therefore, mental toughness. These results suggest that effective methods for enhancing mental toughness in adolescents should be multifaceted. Additionally, it highlights the importance of identifying and regulating chronotype tendencies among adolescents, while also emphasizing the need to increase resilience in this demographic.</p>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vaginal screening for group B streptococcus using PCR in pregnant women with unknown colonization status: Impact on newborn monitoring for early-onset sepsis. 使用 PCR 对定植状况不明的孕妇进行 B 群链球菌阴道筛查:对新生儿早期败血症监测的影响。
IF 1.3 4区 医学
Archives De Pediatrie Pub Date : 2024-09-10 DOI: 10.1016/j.arcped.2024.05.002
Anne Laure Blanquart, Fabien Garnier, Thomas Lauvray, Perrine Coste Mazeau, Sophie Martinez, Cyrille Catalan, Vincent Guigonis, Antoine Bedu, Fabienne Mons, Laure Ponthier
{"title":"Vaginal screening for group B streptococcus using PCR in pregnant women with unknown colonization status: Impact on newborn monitoring for early-onset sepsis.","authors":"Anne Laure Blanquart, Fabien Garnier, Thomas Lauvray, Perrine Coste Mazeau, Sophie Martinez, Cyrille Catalan, Vincent Guigonis, Antoine Bedu, Fabienne Mons, Laure Ponthier","doi":"10.1016/j.arcped.2024.05.002","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.05.002","url":null,"abstract":"<p><strong>Background: </strong>Early-onset neonatal sepsis represents a diagnostic challenge, as it is a cause of neonatal mortality and morbidity. Guidelines for the prevention of group B streptococcus (GBS) infection recommend that all pregnant women must be screened for GBS carriage at the end of pregnancy, with intrapartum antibiotic prophylaxis being provided for GBS carriers. If vaginal culture is not available, GBS polymerase chain reaction (GBS-PCR) is an alternative option for this type of screening. In our unit, GBS-PCR is performed when pregnant women present to the delivery room with ongoing labor and with no results of culture GBS screening available. The main objective of this study was to evaluate the impact of the results of GBS-PCR on monitoring modifications in newborns of mothers with unknown GBS status. The secondary objectives were to confirm the feasibility of a GBS-PCR-based screening method in everyday practice and to evaluate the impact of GBS-PCR results on the modification of intrapartum antibiotic therapy in pregnant women.</p><p><strong>Method: </strong>A retrospective, single-center, observational study was conducted for 1 year. For dyads with GBS-PCR performed, changes concerning intrapartum antibiotic therapy and the newborn's monitoring were recorded. The feasibility of the method was evaluated by the delay between the GBS-PCR realization and the availability of the result; in addition, the number of GBS-PCR tests that could not be realized were collected.</p><p><strong>Results: </strong>Overall, 60 GBS-PCR samples were tested for 60 pregnant women. Results were obtained for all samples, and the median duration to obtaining the GBS-PCR results was 70 min (60.8-87.2). These results were positive for 11 (18.3 %) women and led to monitoring modifications for two infants. In total, 27 pregnant women (45 %) had modifications in their antibiotic therapy due to the GBS-PCR results.</p><p><strong>Conclusion: </strong>GBS-PCR was quickly available and the results led to changes in maternal antibiotic prophylaxis and in the monitoring level of the newborns.</p>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disordered eating behaviors and associated factors in children and adolescents with type 1 diabetes. 1 型糖尿病儿童和青少年的饮食紊乱行为及相关因素。
IF 1.3 4区 医学
Archives De Pediatrie Pub Date : 2024-08-29 DOI: 10.1016/j.arcped.2024.04.006
Ebru Barsal Çetiner, Zeynep Donbaloğlu, Aynur İnan Yüksel, Berna Singin, Bilge Aydın Behram, Aynur Bedel, Mesut Parlak, Hale Tuhan
{"title":"Disordered eating behaviors and associated factors in children and adolescents with type 1 diabetes.","authors":"Ebru Barsal Çetiner, Zeynep Donbaloğlu, Aynur İnan Yüksel, Berna Singin, Bilge Aydın Behram, Aynur Bedel, Mesut Parlak, Hale Tuhan","doi":"10.1016/j.arcped.2024.04.006","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.04.006","url":null,"abstract":"<p><strong>Object: </strong>As part of their treatment, patients with type 1 diabetes mellitus (DM) have to be very careful with what they eat and with their insulin doses. Therefore, the risk of eating disorders increases in this patient group. In this study, we aimed to determine the disordered eating behaviors of patients with type 1 DM and to evaluate the sociodemographic characteristics, diabetes care behaviors, and quality-of-life scale results that these behaviors may be related to.</p><p><strong>Method: </strong>The sociodemographic characteristics and diabetes treatment data of 191 patients aged 9-18 years with type 1 DM were analyzed. The Pediatric Quality of Life Inventory (PedsQL), the PedsQL 3.0 Diabetes Module, and the Diabetes Eating Problem Survey-Revised (DEPS-R) were applied.</p><p><strong>Results: </strong>The median DEPS-R score of the patients was 18 (19.00), and 44.5 % had a DEPS-R score above 20. A significant correlation was found between age, duration of diabetes, frequency of blood glucose measurement, hemoglobin A<sub>1c</sub> (HbA<sub>1c</sub>) level, body mass index standard deviation score (BMI-SDS), and DEPS-R score. There was no significant difference between girls and boys. Patients with a high DEPS-R score had low scores on the PedsQL and on the PedsQL 3.0 Diabetes Module.</p><p><strong>Conclusion: </strong>The DEPS-R scale is a diabetes-specific, easy-to-use, and effective method for screening patients with type 1 DM for disordered eating behaviors. It can help prevent the progression of disordered eating behaviors to clinical eating disorders in patients with type 1 DM. It would be beneficial to use this scale as a routine screening, especially in clinics where access to a psychologist is not possible.</p>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors of radiographic pneumonia in febrile children with cancer presenting to the emergency department 急诊科癌症发热患儿放射性肺炎的预测因素。
IF 1.3 4区 医学
Archives De Pediatrie Pub Date : 2024-08-01 DOI: 10.1016/j.arcped.2024.04.003
{"title":"Predictors of radiographic pneumonia in febrile children with cancer presenting to the emergency department","authors":"","doi":"10.1016/j.arcped.2024.04.003","DOIUrl":"10.1016/j.arcped.2024.04.003","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;&lt;span&gt;Fever is a common presenting complaint to the pediatric&lt;span&gt; emergency department (PED), especially among &lt;/span&gt;&lt;/span&gt;oncology&lt;span&gt;&lt;span&gt;&lt;span&gt; patients. While bacteremia has been extensively studied in this population, pneumonia has not. Some studies suggest that chest X-ray (CXR) does not have a role in the investigation of &lt;/span&gt;neutropenic fever in the &lt;/span&gt;absence of respiratory symptoms, yet non-neutropenic pediatric oncology patients were excluded from these studies.&lt;/span&gt;&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;We aimed to determine the incidence of CXRs ordered for febrile pediatric oncology patients, irrespective of their absolute neutrophil count (ANC), and to evaluate the rates of radiographic pneumonia as well as predictors of the latter in this group.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Method&lt;/h3&gt;&lt;div&gt;&lt;span&gt;&lt;span&gt;&lt;span&gt;&lt;span&gt;This study was conducted in the PED at the American University of Beirut Medical Center (AUBMC), an Eastern Mediterranean tertiary-care hospital. We conducted a retrospective cohort study of acutely febrile &lt;/span&gt;pediatric cancer patients, younger than 18 years, presenting to a tertiary center from 2014 to 2018. We included one randomly selected febrile visit per patient. Fever was defined as a single oral temperature ≥38 °C within 24 h of presentation. We collected data on &lt;/span&gt;patient characteristics and outcomes. Our primary outcome was radiographic pneumonia; our secondary outcome was whether a CXR was done or not. We defined radiographic pneumonia as a consolidation, &lt;/span&gt;pleural effusion, infiltrate, pneumonia, “infiltrate vs. &lt;/span&gt;atelectasis,” or possible pneumonia mentioned by the radiologist. SPSS was used for the statistical analysis.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;&lt;span&gt;&lt;span&gt;We reviewed a total of 664 medical charts and included data from 342 febrile pediatric patients in our analysis. Of these, 64 (18.7%) had a CXR performed. Overall, 16 (25%) had radiographic pneumonia while 48 (75%) did not. Patients were significantly more likely to have a CXR performed if they presented with upper respiratory tract symptoms, &lt;/span&gt;cough (&lt;/span&gt;&lt;em&gt;p&lt;/em&gt;&lt;span&gt; &lt; 0.001 for both), or abnormal lung auscultation at the bedside (&lt;/span&gt;&lt;em&gt;p&lt;/em&gt; = 0.004). Patients were also less likely to have a CXR done if they were asymptomatic upon admission to the PED (&lt;em&gt;p&lt;/em&gt; &lt; 0.001). However, neither cough nor shortness of breath nor abnormal lung examinations were significant predictors of a positive CXR (&lt;em&gt;p&lt;/em&gt; = 0.17, 0.43, and 0.669, respectively). Patients with radiographic pneumonia were found to be significantly younger (4.29 vs. 6 years, &lt;em&gt;p&lt;/em&gt; = 0.03), with a longer time since their last chemotherapy (15 vs. 7 days, &lt;em&gt;p&lt;/em&gt; = 0.005), and were given intravenous (IV) bolus in the PED (87.5% vs. 56.3%, &lt;em&gt;p&lt;/em&gt; = 0.02). Interestingly, patients with higher white blood cell (WBC) counts were more likely to have radiographic pneumonia (4850 vs. 1750, &lt;em&gt;p&lt;/e","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in the prevalence of language disorders in 4-year-old children: Comparison of health assessment data in nursery schools in Val-de-Marne between the academic years 2018–2019 and 2021–2022 4 岁儿童语言障碍的流行趋势:瓦尔-德-马恩省幼儿园2018-2019学年和2021-2022学年健康评估数据比较。
IF 1.3 4区 医学
Archives De Pediatrie Pub Date : 2024-08-01 DOI: 10.1016/j.arcped.2024.01.001
{"title":"Trends in the prevalence of language disorders in 4-year-old children: Comparison of health assessment data in nursery schools in Val-de-Marne between the academic years 2018–2019 and 2021–2022","authors":"","doi":"10.1016/j.arcped.2024.01.001","DOIUrl":"10.1016/j.arcped.2024.01.001","url":null,"abstract":"<div><h3>Background</h3><div>In the Val-de-Marne department, health check-ups for children in the middle section of nursery school are carried out by the Maternal and Child Protection Service, and allow for the early detection of possible anomalies. Language is evaluated using the ERTL-4 test, which helps to identify a language disorder<span>. Using data collected from health check-ups, the objective of our work was to compare the rates of children referred for language disorder assessment between the academic years 2018–2019 and 2021–2022 as well as the associated risk factors.</span></div></div><div><h3>Method</h3><div>Children who underwent a health check-up during 2018–2019 and 2021–2022 were included. After a descriptive analysis, a logistic regression model was constructed with referral or no referral for a language disorder as a function of the academic year and possible risk or protective factors.</div></div><div><h3>Results</h3><div>Among the 36,816 health check-ups analyzed, the proportion of children referred for language disorder check-ups increased significantly by 3.3 % (<em>p</em> &lt; 0.001). The factors associated with this were male gender ([odds ratio] OR = 1.60, <em>p</em> &lt; 2.2e-16) and schooling in a priority education network (REP), (OR = 1.54, <em>p</em> &lt; 2.2e-16) or REP+ (OR = 2.76, <em>p</em> &lt; 2.2e-16). An association with other disorders was identified (<em>p</em> &lt; 2.2e-16).</div></div><div><h3>Conclusion</h3><div>This study shows that the proportion of children referred for language disorders has increased between the 2 academic years.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信