Archives De Pediatrie最新文献

{"title":"Severe urological involvement in junctional epidermolysis bullosa justifying bladder enlargement by sigmoidocystoplasty and Mitrofanoff appendicovesicostomy","authors":"Marielle Ehilé-Kacou ,&nbsp;Pierre Yves Mure ,&nbsp;Delphine Demede ,&nbsp;Alice Phan ,&nbsp;Justine Bacchetta ,&nbsp;Valeska Bidault ,&nbsp;Bruno Ranchin","doi":"10.1016/j.arcped.2025.01.002","DOIUrl":"10.1016/j.arcped.2025.01.002","url":null,"abstract":"<div><div>The urological complications of junctional epidermolysis bullosa (JEB) are difficult to manage because of the fragility of the skin and mucosa, and are not the subject of any recommendations. We report on 2 cases of chronic lower urinary tract dysfunction causing chronic kidney disease, treated by bladder enlargement with sigmoidocystoplasty and Mitrofanoff appendicovesicostomy after failure of medical treatment and suprapubic catheterisation several times a day. Follow-up was favourable in both children, with kidney function preservation and significant improvement of quality of life.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 4","pages":"Pages 281-284"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anxiety disorders and major depressive disorders in 299 adolescents hospitalized for assessment of common obesity: A retrospective cohort study","authors":"Morgan Seyler ,&nbsp;Caroline Barry ,&nbsp;Alexandra Loisel ,&nbsp;Marie Rose Moro ,&nbsp;Jonathan Lachal ,&nbsp;Hervé Lefèvre","doi":"10.1016/j.arcped.2025.01.004","DOIUrl":"10.1016/j.arcped.2025.01.004","url":null,"abstract":"<div><h3>Background</h3><div>Obesity has major psychosocial impacts in adolescents. Anxiety and depression are the most common psychiatric conditions in adolescents suffering from obesity.</div></div><div><h3>Objectives</h3><div>To measure and discuss the prevalence of psychiatric disorders in adolescents hospitalized for biopsychosocial assessment of common obesity during multidisciplinary care.</div></div><div><h3>Methods</h3><div>This retrospective monocentric study describes mental disorders over a decade (2012–2021) in 299 adolescents with obesity hospitalized for a global somatic and psychiatric assessment. Patients aged 11–18 were included. Sociodemographic data, psychiatric diagnosis, self-report questionnaires (CDI, <em>Children's Depression Inventory,</em> STAIC, <em>State-Trait Anxiety Inventory for children,</em> BES, <em>Binge Eating Scale</em>) were analyzed.</div></div><div><h3>Results</h3><div>27,4 % of adolescents had an anxiety disorder (AD), 18,7 % had a major depressive disorder (MDD) and 49,2 % had no mental disorder. In multiple regression models, exposure to physical violence (<em>p</em> &lt; 0.01), and the BES score (<em>p</em> &lt; 0.05) were also associated with a risk of AD. Exposure to physical violence, year of admission and the BES score were risk factors for MDD (<em>p</em> &lt; 0.05).</div></div><div><h3>Conclusions</h3><div>Prevalence of mental disorders is high and increasing, confirming the psychological suffering in adolescent with obesity. Some present with incomplete clinical profiles. MDD and AD are associated with a personal history of violence and a high BES score, reflecting in some adolescents a phenomenon of compensatory binge eating.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 4","pages":"Pages 261-265"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse events associated with intravenous immunoglobulin infusions in pediatric patients with primary immunodeficiency: A 10-year single-center study","authors":"Murat Özer,&nbsp;Seher Tekeli,&nbsp;Selçuk Doğan,&nbsp;Sema Çetin,&nbsp;Rıdvan Selen,&nbsp;Caner Aytekin","doi":"10.1016/j.arcped.2025.01.008","DOIUrl":"10.1016/j.arcped.2025.01.008","url":null,"abstract":"<div><h3>Background</h3><div>Intravenous immunoglobulin G (IVIg) is used as a replacement therapy in primary immunodeficiency disorders (PIDs). Although IVIg is generally accepted as a safe treatment, the incidence of adverse events (AEs), most of which are mild and transient, varies between 1 % and 81 %. The aim of this study was to determine the adverse effects and influencing factors associated with IVIg replacement therapy in pediatric patients with PID.</div></div><div><h3>Materials and Methods</h3><div>Children with PID who received IVIg replacement therapy between January 1, 2012 and December 31, 2021, at Dr. Sami Ulus Children's Hospital were included in our study.</div></div><div><h3>Results</h3><div>Overall, 69 (52 male, 17 female) patients who received a total of 2,025 IVIg infusions were evaluated. AEs were observed in 40.6 % of the patients and in 8.9 % of the infusions. All AEs encountered in the study were mild to moderate. Immediate-onset AEs were observed in 3.5 % of the infusions and delayed-onset AEs in 5.4 %. Late-onset AEs were not observed. The most commonly observed AEs were headache (<em>n</em> = 50, 2.5 %), fever (<em>n</em> = 37, 1.8 %), and malaise (<em>n</em> = 19, 0.9 %). The most common immediate AE was fever (<em>n</em> = 28, 1.4 %), while the most common delayed AE was headache (<em>n</em> = 44, 2.2 %).</div></div><div><h3>Conclusion</h3><div>AEs encountered in patients with PID receiving IVIg infusions are mild to moderate. Pediatric patients should be followed up for delayed AEs by contacting their families after the infusion is completed and should be questioned before the next infusion. IVIg replacement is a safe treatment when given with an appropriate premedication and infusion rate.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 4","pages":"Pages 231-237"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of early MRI in predicting the risk of hippocampal sclerosis in children with febrile status epilepticus","authors":"Rose Germain ,&nbsp;Mathilde Le Floch ,&nbsp;Marine Dubois ,&nbsp;Pauline Cloarec ,&nbsp;Raphaël Chouteau ,&nbsp;Bertrand Bruneau","doi":"10.1016/j.arcped.2024.12.007","DOIUrl":"10.1016/j.arcped.2024.12.007","url":null,"abstract":"<div><h3>Background</h3><div>Epilepsy is the main complication of febrile status epilepticus (FSE) in children. The association between FSE and the development of hippocampal sclerosis (HS) and mesial temporal lobe epilepsy (MTLE) is controversial.</div></div><div><h3>Objectives</h3><div>This study primarily aimed to evaluate the role of magnetic resonance imaging (MRI) in diffusion-weighted imaging (DWI) sequence during the acute phase of FSE in predicting long-term development of HS and epilepsy. The secondary objective was to assess the value of arterial spin labeling (ASL) perfusion MRI in the acute phase of FSE.</div></div><div><h3>Methods and settings</h3><div>Patients with a first episode of FSE between 6 months and 5 years of age who underwent early MRI were retrospectively included. MRI analysis focused on the DWI signal and the presence of perfusion abnormalities on ASL imaging. We also examined the first electroencephalogram (EEG) during the acute phase. Long-term follow-up analysis assessed the occurrence of HS on MRI scans and the development of epilepsy.</div></div><div><h3>Results</h3><div>A total of 15 children were included. The presence of restricted diffusion areas on MRIs performed in the acute phase after FSE was significantly associated with the later development of HS. However, the association between restricted diffusion areas on early MRIs and the development of pharmaco-resistant epilepsy on follow-up, found in 3 patients, was not statistically significant. There was a trend for an association between early ASL perfusion MRI changes and EEG findings when both examinations were performed closely.</div></div><div><h3>Conclusion</h3><div>Early DWI-MRI seems to play a major role in the prognostic evaluation of FSE in children. It may help to determine hippocampal involvement and assess the risk of subsequent HS. However, the study data are insufficient to conclude on the association between diffusion abnormalities and the development of MTLE. Although ASL perfusion may provide additional insight, more data are needed.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 4","pages":"Pages 244-254"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioral parenting intervention for parents of preschool-aged children born moderately and late preterm: An experimental study","authors":"Géraldine Maigret,&nbsp;Edouard Gentaz,&nbsp;Fleur Lejeune","doi":"10.1016/j.arcped.2025.03.001","DOIUrl":"10.1016/j.arcped.2025.03.001","url":null,"abstract":"<div><h3>Background</h3><div>Prematurity can be associated with difficulties in emotional and behavioral regulation in children, leading to short- and long-term impacts on parental dynamics. However, moderate-late preterm children and their parents rarely receive follow-up care.</div></div><div><h3>Objectives</h3><div>The aim of this current study was to evaluate a Behavioral Parenting Intervention (BPI) specifically developed for parents of preschool-aged moderate-late preterm children, to prevent their potential difficulties in emotional and behavioral regulation.</div></div><div><h3>Method</h3><div>Thirty-eight families participated in a program consisting of 7 therapy sessions. Each experimental group was matched with a control group; the control group would become the experimental group in the following session. Parents completed questionnaires one week before the start of the program (T1) and at the end of the 7th therapy session to measure immediate effects (T2). Social validity measures were also added to this study to assess the feasibility and acceptability of our program.</div></div><div><h3>Results</h3><div>We primarily observed positive effects on the Parental Stress Index total (PSI) in the population 1. For the control group, there was no significant difference between PSI Total scores at T1 <em>(M</em> <em>=</em> <em>101.1, SD = 22.2)</em> and T2 <em>(M</em> <em>=</em> <em>101.5, SD = 19.8).</em> In contrast, the experimental group showed a significant reduction in PSI total scores from T1 <em>(M</em> <em>=</em> <em>105, SD = 23.2)</em> to T2 <em>(M</em> <em>=</em> <em>93.3, SD = 21.3),</em> with <em>p</em> &lt; .001. Similar effects were observed for both the Parent Distress and the Difficult Child subscales.</div></div><div><h3>Conclusion</h3><div>While our results are modest, the measures of social validity and our high satisfaction rates indicate the importance and necessity of a parenting intervention aimed at moderately preterm children beyond the initial phase of early development. Future research should aim to facilitate access and increase family engagement to improve the effectiveness of this type of intervention.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 4","pages":"Pages 223-230"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical ventilation in pediatric hospitals in Senegal","authors":"Amadou Sow ,&nbsp;Aliou Thiongane ,&nbsp;Abou Ba ,&nbsp;Younoussa Kéita ,&nbsp;Papa M. Faye ,&nbsp;Amadou L. Fall ,&nbsp;Djibril Boiro ,&nbsp;Ndeye Fatou Sow ,&nbsp;Aliou A. Ndongo ,&nbsp;Assane Sylla ,&nbsp;Ousmane Ndiaye","doi":"10.1016/j.arcped.2025.01.007","DOIUrl":"10.1016/j.arcped.2025.01.007","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Mechanical ventilation (MV) requires an efficient technical platform and experienced staff. The objective of this study was to evaluate the practice of MV in a pediatric intensive care unit in Senegal.</div></div><div><h3>Methods</h3><div>A total of 102 patients were included. The indications for intubation were respiratory failure in 51% of cases, circulatory failure in 29%, septic shock in 13%, and other indications in 5%. The average delay to intubation after admission was 1.86 days (1 h to 5 days). The mortality rate was 43%.</div></div><div><h3>Conclusion</h3><div>The construction of new and dedicated infrastructures, the training of personnel, and the improvement of the technical platform can lead to a reduction in the infant and child morbidity and mortality associated with MV.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 4","pages":"Pages 278-280"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementing an antibiotic stewardship program to reduce the duration of antibiotics in community-acquired pneumonia: Experience in a French pediatric hospital","authors":"Lise Martin Perceval ,&nbsp;Matthieu Wargny ,&nbsp;Myriam Benhamida ,&nbsp;Morgane Dumortier ,&nbsp;Christèle Gras-Le Guen ,&nbsp;Dominique Navas ,&nbsp;Elise Launay","doi":"10.1016/j.arcped.2025.02.002","DOIUrl":"10.1016/j.arcped.2025.02.002","url":null,"abstract":"<div><h3>Objective</h3><div>This work used a before–after study to evaluate the impact of a multifaceted stewardship intervention on the recommended duration of antibiotic treatment (5 vs 10 days) for non-severe community-acquired pneumonia (CAP) in pediatrics.</div></div><div><h3>Methods</h3><div>Children under age 15 years and 3 months who consulted for CAP in the emergency care unit of Nantes University Hospital from November 2019 to January 2020 and from December 2020 to April 2021 were included. Before the second period, the updated protocol was presented at a local meeting, sent by e-mail, and added to the internal network; physicians’ knowledge was tested through clinical situations and answers to the questionnaire as well as pocket cards were distributed. The main outcome was the absolute and relative difference in prescription adequacy according to the recommended duration of antibiotic therapy (5 days) before and after the intervention.</div></div><div><h3>Results</h3><div>We included 134 children: 71 and 63 before and after the intervention respectively. The proportion of adequate duration of antibiotic therapy prescribed was increased: 27 (38.0 %) children in the “before” group versus 50 (79.4 %) in the “after” group (<em>p</em> &lt; 0.0001). The prescription adequacy ratio (after/before) was 2.09 (95 %CI, 1.51–2.88). The mean treatment duration was significantly higher in the “before” than “after” group: 7.3 versus 5.7 days (<em>p</em> &lt; 0.0001). A total of 155 days of treatment per 100 treated children was avoided. The proportion of correctly prescribed dosages was higher in the “after” than the “before” group: + 18 % (<em>p</em> = 0.03). The proportion of nasopharyngeal PCR tests performed was significantly higher after than before the intervention (<em>p</em> &lt; 0.0001). Chest X-rays were performed in almost all children in both groups.</div></div><div><h3>Conclusion</h3><div>This multifaceted stewardship intervention demonstrated clinically and statistically significant results concerning the prescribed antibiotic therapy duration at individual and population levels and could be extended to other care centers and other situations.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 4","pages":"Pages 217-222"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growth response to medical intervention in an observational real-life cohort of children with growth delay: A causal inference methods study","authors":"Mathea Gjoertz ,&nbsp;Alexis Rybak ,&nbsp;Alessio Picco ,&nbsp;Michael Hauschild ,&nbsp;Julien Sauser ,&nbsp;Kanetee Busiah","doi":"10.1016/j.arcped.2024.12.004","DOIUrl":"10.1016/j.arcped.2024.12.004","url":null,"abstract":"<div><h3>Background</h3><div>Studies on growth response to medical interventions in children with growth delay are mainly randomized controlled trials (RCTs) and observational studies. RCTs establish cause-effect relationships under controlled conditions but limited generalizability to real-life. Conversely, observational studies reflect real-life conditions but are subject to confounding factors and bias. Data regarding catch-up growth and associated factors in children who do not benefit from medical treatment are lacking.</div></div><div><h3>Objectives</h3><div>To evaluate the causal impact of etiological treatment (ET) versus a wait-and-see approach (WS) on one-year catch-up growth in children with growth delay of different etiologies and to identify factors associated with good catch-up growth independent of the intervention.</div></div><div><h3>Study design</h3><div>Retrospective cohort of children referred for growth delay, defined by height &lt; -2 SD, height &lt; -2 SD from target height, or growth velocity &lt; 0 SD.</div><div>Causal inference methods, including inverse probability treatment weighting (IPTW), and weighted Poisson regression with robust variance, were used to estimate the average treatment effect in the treated and relative risk, respectively. A variable selection procedure was applied using backward selection by Akaike Information Criterion.</div></div><div><h3>Results</h3><div>We included 198 children: 100 with ET and 98 with WS. Main diagnosis was secondary growth failure (42.4 %). Good catch-up growth was more frequent with ET versus WS (31.31% vs. 3.54 %, <em>p</em> &lt; 0.05). Patients in the ET group had a 10.3 times higher chance of achieving one-year good catch-up growth. Young age and low growth velocity at baseline were associated with better catch-up growth, independently of the intervention.</div></div><div><h3>Conclusion</h3><div>ET significantly improves growth catch-up in children with growth delay. Young age and low growth velocity are associated with good catch-up growth, regardless of intervention. The use of IPTW strengthen the validity of the findings in a real-world setting, despite the retrospective study design. This approach highlights the effectiveness of interventions and the robustness of findings through advanced statistical adjustments.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 4","pages":"Pages 238-243"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment outcome of diabetic ketoacidosis and its determinants among children admitted to hospitals in northwest Ethiopia in 2021: A retrospective cross-sectional study","authors":"Mequanint Ayehu Akele ,&nbsp;Rajalakshmi Murugan ,&nbsp;Feven Mulugeta ,&nbsp;Tamalew Alemie Tegegne","doi":"10.1016/j.arcped.2024.11.011","DOIUrl":"10.1016/j.arcped.2024.11.011","url":null,"abstract":"<div><h3>Background</h3><div>Diabetic ketoacidosis (DKA) remains a leading cause of death among children in developing countries.</div></div><div><h3>Objectives</h3><div>To assess the treatment outcome of DKA and its determinants among children admitted to hospitals in northwest Ethiopia.</div></div><div><h3>Methods</h3><div>An institutional-based, retrospective cross-sectional study was conducted among 240 children with DKA. We collected 5-year data by reviewing patient charts using a checklist. Bivariate and multivariate models were used to determine the association of the independent variables with the outcome variable. After multivariate regression, a value of <em>p</em> &lt; 0.05 was considered statistically significant.</div></div><div><h3>Result</h3><div>Of the 240 children with DKA included in the study, 86.7 % recovered and 13.3 % died. Respiratory tract infections (adjusted odds ratio [AOR] = 3.5; 95 % confidence interval [CI]: 1.2–10), sepsis (AOR = 4.9; 95 % CI: 1.45–16.57), cerebral edema (AOR = 5.89; 95 % CI: 1.56–22.3), renal failure (AOR = 3.6; 95 % CI:1.06–12.45), hyponatremia (AOR = 4; 95 % CI:1.02–16.1), hypernatremia (AOR = 7.4; 95 % CI:1.29–42.08), dehydration (AOR = 4; 95 % CI: 1.15–14.03), and not receiving potassium replacement therapy (AOR = 7.4; 95 % CI: 1.29–42.08) were factors significantly associated with death.</div></div><div><h3>Conclusion</h3><div>In this study, the overall mortality of children with DKA was 13.3 %. The major factors associated with death were dehydration, hyponatremia or hypernatremia, respiratory tract infections, sepsis, renal failure, and cerebral edema. Thus, early diagnosis and treatment of these factors are necessary to decrease mortality in children with DKA.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 4","pages":"Pages 266-271"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eating disorders in children under 4 years of age with autism spectrum disorder: Description and determinants","authors":"Clémentine Socie ,&nbsp;Alexandre Descamps ,&nbsp;Béatrice Thouvenin ,&nbsp;Catherine du Fraysseix Peigné ,&nbsp;Véronique Abadie ,&nbsp;Lisa Ouss","doi":"10.1016/j.arcped.2025.02.001","DOIUrl":"10.1016/j.arcped.2025.02.001","url":null,"abstract":"<div><h3>Background</h3><div>Eating disorders in children with autism spectrum disorder (ASD) are multifactorial and complex, and impair their quality of life. The link between eating difficulties and ASD is still controversial, and few studies have focused on very young children with ASD.</div></div><div><h3>Objectives</h3><div>Our objectives were: 1) to characterize the eating disorders of ASD children under 4 years; 2) to study the links between these eating disorders and the characteristics of the child (symptoms and severity of ASD, level of development).</div></div><div><h3>Methods</h3><div>33 ASD children (18 months to 4 years) were included. Their developmental level was assessed by the Brunet-Lézine Revised test (BL-R) and characteristics of ASD by the Autism Diagnosis Interview-Revised (ADI-R). We used a new questionnaire on eating disorders of children between 9 months and 6 years of age that covered 4 dimensions: eating behavior, oro-motor skills, oral and bodily sensory characteristics, and parental impacts and strategies.</div></div><div><h3>Results</h3><div>70 % of parents declared eating disorders in their child, with an early frequent onset beyond 12 months of age. These disorders caused significant parental suffering and worries about the future in two-thirds of parents, and more than half of the parents implemented strategies to handle them. We found two striking results: 1) No statistical link was observed between the severity of an eating disorder and the severity of ASD symptoms or the child's developmental level; 2) Children with better communication and socialization levels had more eating disorders.</div></div><div><h3>Conclusion</h3><div>These results show that eating disorders in our population are probably linked with the relational nature of the act of eating.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 4","pages":"Pages 255-260"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}