Archives of Iranian Medicine最新文献

{"title":"Clinicopathological Pattern of Endometrial Specimens in Women with Abnormal Uterine Bleeding and Ultrasonography Correlation.","authors":"Mohadeseh Karimi, Anahita Alizadeh, Masoumeh Mahmoodi","doi":"10.34172/aim.2024.31","DOIUrl":"10.34172/aim.2024.31","url":null,"abstract":"<p><strong>Background: </strong>Abnormal uterine bleeding (AUB) refers to any symptomatic deviation from normal menstruation. AUB is a common gynecological disorder in non-pregnant women of reproductive age, accounting for approximately 33% of gynecological outpatient visits. The early diagnosis and management cause of AUB is important because of increased incidence of endometrial carcinoma with rapid growth. Transvaginal ultrasound is non-invasive imaging technique used to find endometrial carcinoma before referring patients for invasive techniques. Dilatation and curettage (D&C) and endometrial biopsy are surgical procedures that scrape the endometrial lining of the uterus for diagnosis and treatment. The aim of this study is to describe the clinicopathologic pattern of endometrial specimens in women with AUB and ultrasonographic correlation.</p><p><strong>Methods: </strong>Tissues from endometrial biopsy and curettage of 411 patients with AUB who referred to Shahid Mohammadi hospital were prospectively selected from 2021 to 2023. Patients were divided into three groups based on age and menstrual status including: premenopausal (18-39 years), perimenopausal (40-49 years) and postmenopausal (≥50 years). The results were correlated to patient's age and other data and evaluated with statistical analysis.</p><p><strong>Results: </strong>During the two-year study period, a total of 411 endometrial specimens with clinical diagnosis of AUB were submitted and the results were analyzed. The youngest patient presenting with AUB was 21 years old, while the oldest was 77 years old. The most common complaint was menorrhagia in 201 (48.0%) out of 411 patients. The most common pathology finding in three groups was polyp in 100 (24.3%) cases. Hormonal effect was the next commonly observed pattern seen in 70 (17.0%) cases. P value was calculated as 0.003 which was significant using chi-square for the trend seen in age.</p><p><strong>Conclusion: </strong>Endometrial sampling is a useful tool for evaluation of women with AUB and referring patients for treatment. Histopathological evaluation of the endometrium is very useful in detecting the etiology of AUB. Transvaginal sonography has high sensitivity in detecting polyps.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 4","pages":"216-222"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Phenotype and Disease Course of Inflammatory Bowel Disease in Iran: Results of the Iranian Registry of Crohn's and Colitis (IRCC).","authors":"Bahar Saberzadeh-Ardestani, Amir Ali Khosravi, Fariborz Mansour-Ghanaei, Homayoon Vahedi, Nadieh Baniasadi, Mohammadreza Seyyedmajidi, Baran Parhizkar, Ahmad Hormati, Sayed Jalalledin Naghshbandi, Somaieh Matin, Amir Abbas Hassan Zadeh, Tarang Taghvaei, Mohsen Bahrami, Mandana Rafeey, Mitra Ahadi, Hassan Vossoughinia, Hashem Muosavi, Shahsanam Gheibi, Roya-Sadat Hosseini-Hemmatabadi, Abbas Yazdanbod, Saied Matinkhah, Farshad Sheikh Esmaeili, Hafez Fakheri, Seyed Hamid Moosavy, Iradj Maleki, Siavosh Nasseri-Moghaddam, Bardia Khosravi, Fatemeh Farahmand, Mehri Najafi, Hosein Alimadadi, Masoud Malekzadeh, Amir Anushiravani, Amir Kasaeian, Sudabeh Alatab, Anahita Sadeghi, Amir Reza Radmard, Shadi Kolahdoozan, Zeynab Rajabi, Ali Reza Sima","doi":"10.34172/aim.2024.27","DOIUrl":"10.34172/aim.2024.27","url":null,"abstract":"<p><strong>Background: </strong>Data on the epidemiology of inflammatory bowel disease (IBD) in the Middle East are scarce. We aimed to describe the clinical phenotype, disease course, and medication usage of IBD cases from Iran in the Middle East.</p><p><strong>Methods: </strong>We conducted a cross-sectional study of registered IBD patients in the Iranian Registry of Crohn's and Colitis (IRCC) from 2017 until 2022. We collected information on demographic characteristics, past medical history, family history, disease extent and location, extra-intestinal manifestations, IBD medications, and activity using the IBD-control-8 questionnaire and the Manitoba IBD index, admissions history, history of colon cancer, and IBD-related surgeries.</p><p><strong>Results: </strong>In total, 9746 patients with ulcerative colitis (UC) (n=7793), and Crohn's disease (CD) (n=1953) were reported. The UC to CD ratio was 3.99. The median age at diagnosis was 29.2 (IQR: 22.6,37.6) and 27.6 (IQR: 20.6,37.6) for patients with UC and CD, respectively. The male-to-female ratio was 1.28 in CD patients. A positive family history was observed in 17.9% of UC patients. The majority of UC patients had pancolitis (47%). Ileocolonic involvement was the most common type of involvement in CD patients (43.7%), and the prevalence of stricturing behavior was 4.6%. A prevalence of 0.3% was observed for colorectal cancer among patients with UC. Moreover,15.2% of UC patients and 38.4% of CD patients had been treated with anti-tumor necrosis factor (anti-TNF).</p><p><strong>Conclusion: </strong>In this national registry-based study, there are significant differences in some clinical phenotypes such as the prevalence of extra-intestinal manifestations and treatment strategies such as biological use in different geographical locations.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 4","pages":"183-190"},"PeriodicalIF":2.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Global Road Traffic Death Rate and Human Development Index from 2000 to 2019: A Trend Analysis.","authors":"Mohammad Sayari, Mohammad Reza Rahmanian Haghighi, Kamran Bagheri Lankarani, Sulmaz Ghahramani, Behnam Honarvar","doi":"10.34172/aim.2024.18","DOIUrl":"10.34172/aim.2024.18","url":null,"abstract":"<p><strong>Background: </strong>Numerous studies on the association between the human development index (HDI) and road traffic death rate (RTDR) merely focus on developed countries, not reflecting the relationship between the HDI components and RTDR in a time-trend analysis. Accordingly, this study analyzes the trends of RTDR and their association with the HDI and its components from 2000 to 2019.</p><p><strong>Methods: </strong>The RTDR data of 154 countries were imported into the unconditional latent growth model (LGM) to assess the RTDR trends. The impact of the HDI and its components (viz., education, income, and life expectancy [LE viz]) on the trajectory of RTDR was also evaluated using the conditional LGM.</p><p><strong>Results: </strong>The results of the unconditional LGM indicated an overall decreasing trend in RTDR. The conditional LGM results revealed the negative effect of the HDI and its components on the model parameters. The findings of random forests indicated that education and LE were the most crucial variables.</p><p><strong>Conclusion: </strong>Overall, this study emphasizes the significance of HDI and its components, particularly education and LE, in lowering the number of traffic fatalities. In this sense, improving formal education and LE could be one of the main policies that policymakers could consider to reduce RTDR.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 3","pages":"113-121"},"PeriodicalIF":2.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Mental Disorders Among Families of ISIS Captives Residing in Sulaymaniyah With the Native Population in 2023: A Cross-sectional Study.","authors":"Bakhtyar Zrar Rahman, Mansour Bayrami, Khalil Esmaielpour","doi":"10.34172/aim.2024.21","DOIUrl":"10.34172/aim.2024.21","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to compare the level of mental disorders among families of ISIS captives residing in Sulaymaniyah with the native population in 2023.</p><p><strong>Methods: </strong>In the present descriptive-analytical cross-sectional study, a total of 383 ISIS captives by census aged 18-60 years were selected, along with an equal number of matched native individuals from Sulaymaniyah in terms of demographic characteristics. The data collection tool was the SCL-90 questionnaire. The 90-R-SCL interview and test were used to assess the level of symptoms related to mental disorders.</p><p><strong>Results: </strong>The results showed statistically significant differences between ISIS captives and the native population in terms of the total psychological disorder mean score (2.54±0.30 vs. 1.52±0.16; <i>P</i><0.001), Global Severity Index (GSI) (253.40±32.82 vs. 137.03±14.74; <i>P</i><0.001) and the mean scores of the dimensions of psychological disorder including: physical complaint (2.52±0.45 vs. 1.67±0.54; <i>P</i><0.001), obsessive compulsive disorder (2.51±0.43 vs. 1.50±0.44; <i>P</i><0.001), disorder in interpersonal relationships (2.55±0.44 vs. 19.10±0.29; <i>P</i><0.001), depressive disorder (2.60±0.41 vs. 1.60±0.55; <i>P</i><0.001), anxiety disorder (2.50±0.41 vs. 12.10±0.29; <i>P</i><0.001), aggression disorder (2.55±0.49 vs. 19.10±0.40; <i>P</i><0.001), morbid fear disorder (2.55±0.45 vs. 1.48±0.45; <i>P</i><0.001), paranoid ideation disorder (2.49±0.55 vs. 1.39±0.40; <i>P</i><0.001), and psychotic disorder (2.47±0.43 vs. 1.52±0.57; <i>P</i><0.001).</p><p><strong>Conclusion: </strong>The findings of this study suggest that ISIS captives suffer from multiple psychological disorders, and the presence of more severe mental disorders among this population necessitates comprehensive psychiatric and psychological services for them.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 3","pages":"135-141"},"PeriodicalIF":2.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing Hepatotoxicity Caused by Anti-tuberculosis Drugs: A Comparative Study of Approaches.","authors":"Faeze Abbaspour, Malihe Hasannezhad, Hossein Khalili, SeyedAhmad SeyedAlinaghi, Sirous Jafari","doi":"10.34172/aim.2024.19","DOIUrl":"10.34172/aim.2024.19","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) is one of the oldest and most well-known diseases that has been associated with humans for many years and remains a global health challenge today. Timely diagnosis and proper treatment are crucial for controlling and preventing the spread of the disease. While anti-TB drugs offer many benefits, inadequate monitoring can lead to a range of side effects, including hepatotoxicity, which is a major concern and can cause treatment discontinuation. The aim of this study was to determine the approach to the hepatotoxicity of anti-TB drugs and to investigate potential relationships between demographic factors, underlying medical conditions, and successful retreatment outcomes for hepatotoxicity induced by anti-TB drugs.</p><p><strong>Methods: </strong>For this study, we reviewed the medical records of patients who experienced hepatotoxicity due to anti-TB treatment and were admitted to the infectious ward of Imam Khomeini Hospital between April 2015 and February 2019. The data were collected using a questionnaire.</p><p><strong>Results: </strong>The findings indicated that the female gender, weight loss at the beginning of hospitalization, <i>hepatitis C virus</i>, <i>hepatitis B virus (HBV)</i>, heart disease, and high levels of aspartate aminotransferase (AST) and alanine transaminase (ALT) at the beginning of hepatotoxicity are risk factors for failure to the retreatment of hepatotoxicity. There were two different approaches to the anti-TB retreatment regimen. The first approach involved gradually starting the drugs in full dose, while the second approach encompassed starting the drugs in the minimum dose and then increasing to the maximum dose. The results demonstrated no significant difference between the two approaches to managing hepatotoxicity induced by anti-TB drugs.</p><p><strong>Conclusion: </strong>Drug-induced hepatotoxicity is a common occurrence that often results in treatment discontinuation. Understanding the prevalence of this complication and identifying appropriate methods of rechallenge treatment is crucial to reducing complications and mortality rates.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 3","pages":"122-126"},"PeriodicalIF":2.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Outbreak of Home Distillation Methanol Poisoning in Turkey During the COVID-19 Pandemic: A Single Center Experience.","authors":"Sertaç Güler, Dilber Üçöz Kocaşaban","doi":"10.34172/aim.2024.23","DOIUrl":"10.34172/aim.2024.23","url":null,"abstract":"<p><strong>Background: </strong>Causes of methanol poisoning may include accidental or suicidal use, as well as self home-distillation. In this study, it was aimed to evaluate clinical characteristics, laboratory findings, and outcomes of home-distillation methanol poisoning in two different time periods as an outbreak during the pandemic. The source of the methanol poisoning in all patients was home-brewing or distillation of methanol.</p><p><strong>Methods: </strong>The study was a single-center, retrospective, and observational case-control study. Patients over 18 years of age, in 2 different periods in the form of an outbreak due to home-distillation of methanol between April 1, 2020, and April 1, 2022, when the coronavirus disease 19 pandemic was intensely experienced in Turkey, were included in this study.</p><p><strong>Results: </strong>A total of 43 patients were included in the study. Of these patients, 22 were exposed to methanol between July and August 2020, and 21 patients were exposed to methanol in December 2021. Overall, 20 patients (46.5%) died, while 23 (53.5%) out of 43 patients recovered with or without sequelae. Patients with low blood pressure, oxygen saturation values, Glasgow Coma Scale (GCS) scores, high blood glucose levels, metabolic acidosis (pH<7.11), and high lactate levels (lactate>4.50 mmol/L) at admission had a statistically significantly worse prognosis.</p><p><strong>Conclusion: </strong>In methanol poisoning due to home brewing, low blood pressure, oxygen saturation, and impaired consciousness at the time of admission were clinical findings associated with mortality. In terms of laboratory findings, especially severe metabolic acidosis and lactate elevation were observed in the group that was mortal despite treatment.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 3","pages":"151-158"},"PeriodicalIF":2.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140855664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synchronous Double Primary Angiosarcoma Originating from the Stomach and Rectum: A Case Report and a Literature Review.","authors":"Tanju Kapagan, Nilufer Bulut, Gokmen Umut Erdem, Suleyman Yıldırım, Zeynep Betul Erdem, Halil Sahin","doi":"10.34172/aim.2024.25","DOIUrl":"10.34172/aim.2024.25","url":null,"abstract":"<p><p>Angiosarcomas originating from the gastrointestinal tract are rare but highly aggressive tumors with poor prognosis. These tumors can be misdiagnosed as benign and malignant gastrointestinal tract lesions. The definitive histological diagnosis of angiosarcomasis made by pathologists based on immunohistochemical analysis demonstrating cluster of differentiation 31 (CD31), factor VIII-related antigen (FVIIIRAg), erythroblast transformation specific related gene (ERG), and cluster of differentiation 34 (CD34). Angiosarcomas are treated with a single or multimodality approach that may include resection, radiotherapy, chemotherapy, and palliative care, depending on the stage of disease and the condition of the patient. No matter the treatment option, metastasis and death rates are substantially highin patients with angiosarcoma. In this context, a 59-year-old male with synchronous double primary angiosarcoma arising from the gastric and rectum who presented with the complaint of abdominal pain and distention to the outpatient clinic is presented in this case report, along with a brief literature review.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 3","pages":"168-173"},"PeriodicalIF":2.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Confounding Role of Graft-Versus-Host Disease in Animal Models of Cancer Immunotherapy: A Systematic Review.","authors":"Hami Ashraf, Mohammad Heydarnejad, Farid Kosari","doi":"10.34172/aim.2024.24","DOIUrl":"10.34172/aim.2024.24","url":null,"abstract":"<p><strong>Background: </strong>Cancer immunotherapy has emerged as a transformative approach for treating various malignancies, including melanoma, lung cancer, breast cancer, and leukemia. Animal models have been instrumental in elucidating the mechanisms and potential of these therapies. However, graft-versus-host disease (GVHD) is an inherent challenge in these studies, primarily because the introduction of foreign immune cells or tissues often triggers immune responses.</p><p><strong>Methods: </strong>A detailed systematic search was conducted across various scientific databases, including PubMed, Scopus, Embase, and Web of Science. The search aimed to identify peer-reviewed articles published in English from January 2000 to September 2023. Keywords and phrases used in the search included \"Graft-versus-Host Disease\", \"GVHD\", \"animal models\", \"cancer immunotherapy\", and combinations thereof. Boolean operators (AND/OR) were employed to refine the search. Finally, 6 articles were included in this systematic review, which is registered on PROSPERO (ID number CRD42024488544).</p><p><strong>Results: </strong>Our systematic review identified several mechanisms employed in animal studies to mitigate the confounding effects of GVHD. These included genetically modified mouse models, immunosuppressive drugs, and humanized mice. Furthermore, the review highlights innovative approaches such as selective T-cell depletion and the use of specific cytokine inhibitors.</p><p><strong>Conclusion: </strong>By systematically identifying and mitigating the confounding effects of GVHD, we can significantly improve the predictive validity of preclinical trials, obtain broadly applicable findings, improve the efficiency of drugs, enhance safety profiling, and develop better therapeutic strategies. This approach is crucial in ensuring that the immunotherapeutic strategies developed in the laboratory are reflective of the human physiological response, thereby bridging a critical translational gap in oncological research.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 3","pages":"159-167"},"PeriodicalIF":2.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognosis of Methanol Poisoning in a Developing Setting.","authors":"Mohammad Reza Sasani, Hossein Molavi Vardanjani, Zahra Mehdipour Namdar, Marjan Jeddi, Shiva Seif, Sogol Sedighi, Seyed Amirreza Akhlagh, Dena Firouzabadi, Amirreza Dehghanian","doi":"10.34172/aim.2024.20","DOIUrl":"10.34172/aim.2024.20","url":null,"abstract":"<p><strong>Background: </strong>Methanol-poisoning can be a challenging cause of mortality. Identifying the epidemiological, clinical, and para-clinical determinants of outcome in methanol-poisoning patients could be a step forward to its management.</p><p><strong>Methods: </strong>In this hospital-based cohort study, 123 methanol-poisoning patients were included. Data on background variables, details of methanol consumption, and laboratory assessments were recorded for each patient. Patients underwent brain CT scans without contrast. We evaluated the association of all gathered clinical and para-clinical data with patients' outcome and length of hospital stay (LOS). Independent association of potential determinants of death, and LOS were modeled applying multivariable logistic, and Ordinary Least Square regressions, respectively. Odds ratio (OR), and regression coefficient (RC), and their 95% confidence intervals (CIs) were estimated.</p><p><strong>Results: </strong>Most of the study population were male (n=107/123). The mean age of the participants was 30.3±9.1 years. Ninety patients (73.2%) were reported as being conscious on admission, and 34.3% of patients were identified with at least one abnormality in their CT scan. Level of consciousness (LOC) (OR: 42.2; 95% CI: 2.35-756.50), and blood pH (OR: 0.37; 95% CI: 0.22-0.65) were associated with death. Supratentorial edema (RC: 17.55; 95% CI: 16.95-18.16) were associated with LOS.</p><p><strong>Conclusion: </strong>Besides LOC, patients with any abnormality in their brain CT scan on admission were found to be at higher risk of death, and patients with supratentorial edema were at risk of longer LOS. Brain CT-scan on admission should be considered as a part of the routine procedure during the management of methanol-poisoning.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 3","pages":"127-134"},"PeriodicalIF":2.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the Emergency Care of Iranian and Afghan Patients During the COVID-19 Pandemic.","authors":"Milad Ahmadi Gohari, Maryam Chegeni, Mohammad Hossein Mehrolhassani, Ali Akbar Haghdoost, Moghaddameh Mirzaee","doi":"10.34172/aim.2024.22","DOIUrl":"10.34172/aim.2024.22","url":null,"abstract":"<p><strong>Background: </strong>This study investigated the quality of inpatient care provided to Afghan immigrants in Iran during the COVID-19 pandemic (February 2019 to March 2021). For this purpose, the services received by Afghan immigrants were compared with those received by Iranian citizens.</p><p><strong>Methods: </strong>Two emergency services (traumas with 8080 victims and 8,686 patients hospitalized with severe COVID-19 infection) were taken into consideration. The records of all patients, including the Afghan immigrants, in two referral hospitals in Kerman were reviewed, and the main variables were the length of hospitalization (LoH), intensive care unit (ICU) admission rate, and death rate. Quantile regression, multiple logistic regression, and Cox regression were used to analyze the data.</p><p><strong>Results: </strong>The median and interquartile range of LoH for Afghan and Iranian nationals admitted due to traumas were 3.0±4.0 and 2.0±4.0, respectively (<i>P</i><0.01). Moreover, the chance of Afghan nationals being admitted to the ICU (38%, odds ratio=1.38; 95% confidence interval [CI]=1.12; 1.69) and the hazard of death (60%, hazard rate=1.60; 95% CI=1.03; 2.49) were higher compared to Iranian nationals, which is statistically significant. However, no significant differences were observed between the COVID-19 patients from the two nationalities in terms of the median LoH, the odds of being admitted to the ICU, and the hazard of death due to COVID-19.</p><p><strong>Conclusion: </strong>Afghan nationals admitted to the hospital due to traumas were more likely to be admitted to ICUs or die compared to Iranian citizens. It seems that Afghan patients who had traumas went to the hospitals with more serious injuries. There was no difference between Afghan and Iranian patients in terms of COVID-19 consequences. Following the findings of this study, it seems that justice in treatment has been fully established for Afghan patients in Iran.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 3","pages":"142-150"},"PeriodicalIF":2.1,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}