Archives of Iranian Medicine最新文献

{"title":"Effect of Music on Anxiety and Fatigue in Cancer Patients Undergoing Chemotherapy: A Randomized Controlled Trial.","authors":"Havva Gezgin Yazıcı, Çiğdem Ökten, Esra Karabulut, Mehmet Aliustaoğlu","doi":"10.34172/aim.31258","DOIUrl":"10.34172/aim.31258","url":null,"abstract":"<p><strong>Background: </strong>Anxiety and fatigue are symptoms typically experienced by cancer patients undergoing chemotherapy. In dealing with these symptoms, listening to music may help patients.</p><p><strong>Methods: </strong>The randomized controlled study was conducted between May 1, 2022 and November 10, 2022 with 60 patients treated in the outpatient chemotherapy unit. The data were gathered using a patient information form, Brief Fatigue Inventory, and the State Trait Anxiety Inventory. In addition to standard treatment and care, 30-minute music was played with a passive listening method in a total of three cycles of chemotherapy in the intervention group patients who completed the first cycle and visited for the second cycle of chemotherapy.</p><p><strong>Results: </strong>According to the analysis of covariance (ANCOVA) findings, the group variable significantly affected the post-test state anxiety scores when an adjustment was made for pre-test state anxiety scores (F=240.398, <i>P</i><0.001, η²=0.808). In addition, pre-test state anxiety scores affected post-test results (F=7.925, <i>P</i>=0.007, η²=0.122). According to the ANCOVA findings, the group variable significantly affected the post-test trait anxiety scores (F=235.243, <i>P</i><0.001, η²=0.805). In addition, pre-test trait anxiety scores affected post-test results (F=34.977, <i>P</i><0.001, η²=0.380). According to ANCOVA results, the group variable significantly affected post-test fatigue scores (F=79.201, <i>P</i><0.001, η²=0.582). In addition, pre-test scores affected post-test scores (F=11.082, <i>P</i>=0.002, η²=0.163).</p><p><strong>Conclusion: </strong>We observed that music had positive effects on fatigue and anxiety levels in cancer patients undergoing chemotherapy. It may be recommended to include music intervention in nursing practices for cancer patients during chemotherapy. The study results demonstrated that music intervention can be used in nursing practices for cancer patients during chemotherapy. Its low-cost and non-invasive nature also provide ease of application. Therefore, we can recommend the application of music intervention in outpatient chemotherapy units.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 11","pages":"611-617"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toll-Like Receptors Agonists: First-Line Defense Tools in the Pandemic Preparedness Arsenal?","authors":"Farrokh Habibzadeh, Parham Habibzadeh, Mihai G Netea, Mahboobeh Yadollahie","doi":"10.34172/aim.31792","DOIUrl":"10.34172/aim.31792","url":null,"abstract":"","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 11","pages":"629-632"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of AI in Competency-Based Medical Education: Using EPA as the Magicbox.","authors":"Ali Dabbagh, Firoozeh Madadi, Bagher Larijani","doi":"10.34172/aim.31795","DOIUrl":"10.34172/aim.31795","url":null,"abstract":"","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 11","pages":"633-635"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hairy Cell Leukemia Following Acute Myeloid Leukemia, Concomitant or Secondary?","authors":"Zhang Bingyao, Fu Zhaoqiang, Zhang Xuxi, Yang Qian, Qin Youwen","doi":"10.34172/aim.28846","DOIUrl":"10.34172/aim.28846","url":null,"abstract":"<p><p>A 62-year-old man diagnosed with acute myeloid leukemia (AML) showed limited responses to two courses of azacitidine (AZA)+Venetoclax (VEN) therapy. Twenty days after being transferred to our hospital, flow cytometry with broad antigen coverage and mutation analysis confirmed the presence of a second malignancy, hairy cell leukemia (HCL). Following haploidentical combined umbilical cord blood transplantation, the patient achieved complete remission (CR) for both AML and HCL. This CR has been maintained for the past 14 months. Patients with dual hematologic malignancies may not respond well to conventional therapy regimens. Early initiation of hematopoietic stem cell transplantation is beneficial for improving prognosis and extending overall survival.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 11","pages":"636-638"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scalp Lesion as the First Manifestation of Pancreatic Adenocarcinoma, A Very Rare Case.","authors":"Luis Posado-Domínguez, Jonnathan Roldan-Ruiz, María Martin-Galache, Alejandra Ruiz-Villanueva, Maria L Perez-García","doi":"10.34172/aim.31235","DOIUrl":"10.34172/aim.31235","url":null,"abstract":"<p><p>Pancreatic adenocarcinoma is one of the most aggressive tumors. Its diagnosis is usually made in locally advanced or metastatic disease and survival is less than one year. The most frequent sites of metastatic involvement are the liver, peritoneum and lungs. Other organs such as the bones or the brain may be affected to a lesser extent. Cutaneous involvement of pancreatic adenocarcinoma is extremely rare with less than 150 cases reported in the literature since 1960. Most cases with cutaneous involvement involve the periumbilical region, in a lesion known as \"Sister Mary Joseph's Node\". Scalp metastases are very rare and their diagnosis suggests advanced disease and the prognosis will be dismal. It is very important to perform a complete physical examination and a global anamnesis to guide the request for diagnostic tests. Once the diagnosis of pancreatic adenocarcinoma has been made, a global assessment will be necessary, involving different medical specialists, nurses, psychologists and social workers among others. In many cases, supportive care is the mainstay of treatment.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 11","pages":"639-642"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling Macrosomia Risks of Non-Diabetic Women: Insights from Second Trimester Maternal Lipid Profiles.","authors":"Ahkam Göksel Kanmaz, Yasemin Alan, Murat Alan, Emrah Töz","doi":"10.34172/aim.31914","DOIUrl":"10.34172/aim.31914","url":null,"abstract":"<p><strong>Background: </strong>Macrosomia, characterized by excessive fetal growth, is common in infants born to women with pre-gestational diabetes and gestational diabetes mellitus (GDM). However, macrosomia, which leads to birth-related maternal and fetal complications and metabolic complications in the adolescence of the affected fetuses, also occurs in the pregnancies of non-diabetic women. This study aims to identify the association between second-trimester lipid profiles and macrosomia in non-diabetic pregnant women to aid in early diagnosis.</p><p><strong>Methods: </strong>This retrospective cohort study included 8,956 patients who delivered at a tertiary care center between 2017 and 2019. Exclusion criteria encompassed pre-existing diabetes, GDM, preeclampsia (PE), intrahepatic cholestasis of pregnancy, obesity, fetal chromosomal or genetic abnormalities, tobacco, alcohol, or drug use affecting lipid metabolism. Participants were divided into two groups: 621 with macrosomia and 873 controls. Second trimester maternal lipid profiles and demographic variables such as age, pregnancy week, and gender were assessed.</p><p><strong>Results: </strong>In the study cohort, maternal age (<i>P</i>=0.002), gestational week (<i>P</i>=0.003), and cesarean section rate (<i>P</i><0.001) were higher in the macrosomic group. High-density lipoprotein-cholesterol (HDL-C) was significantly lower, while total cholesterol (TC), triglycerides (TG), and low-density lipoprotein-cholesterol (LDL-C) were significantly higher in the macrosomic group (<i>P</i><0.001). Univariate analysis revealed positive associations between second-trimester TG (OR 1.023, 95% CI: 1.020‒1.033, <i>P</i><0.001), TC (OR 1.023, 95% CI: 1.016‒1.030, <i>P</i><0.001) and LDL-C (OR 1.036, 95% CI: 1.018-1.054, <i>P</i><0.001) with macrosomia and a negative association with HDL-C (OR 0.954, 95% CI: 0.923‒0.976, <i>P</i><0.001). However, after adjusted multivariable logistic analysis, only TG remained statistically significantly associated with macrosomia (OR 1.054, 95% CI: 1.033‒1.076, <i>P</i><0.001).</p><p><strong>Conclusion: </strong>Our study emphasizes the importance of early recognition and prevention of macrosomia. Structured prospective studies are needed to enhance macrosomia prediction and implement preventive measures, such as dietary modifications. These strategies will be crucial in preventing birth-related complications and long-term health risks, including diabetes, obesity, and cardiovascular diseases, associated with macrosomia.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 11","pages":"624-628"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Correlates of Probable Nonalcoholic Steatohepatitis (NASH) in Pars Cohort Study.","authors":"Amin Nakhostin-Ansari, Iman Menbari Oskouie, Reyhaneh Aghajani, Mohammad Mehdi Khadembashiri, Mohammad Ahmadi, Abdollah Gandomkar, Fatemeh Malekzadeh, Hossein Poustchi, Mohammad Reza Fattahi, Amir Anushiravani, Reza Malekzadeh","doi":"10.34172/aim.30020","DOIUrl":"10.34172/aim.30020","url":null,"abstract":"<p><strong>Background: </strong>Studies on the prevalence of nonalcoholic steatohepatitis (NASH) and the factors associated with its high prevalence among Iranian people are limited. This study evaluated the prevalence of NASH and its associated factors among Iranian adults using Pars Cohort Study (PCS) data.</p><p><strong>Methods: </strong>This cross-sectional study was conducted based on PCS, which includes 40-75-year-old adults from the Valashahr area. NASH was defined as alanine aminotransferase (ALT) higher than 40 U/L without evidence of hepatitis B or C infections. The prevalence of NASH and its associations with basic and demographic characteristics, socioeconomic characteristics, medical history, gastrointestinal symptoms, and laboratory tests were evaluated.</p><p><strong>Results: </strong>Overall, 8734 patients, including 3917 men (44.8%), were enrolled in this study. The mean age of participants was 52.62 years (SD=9.68), and 605 individuals had NASH (6.9%). In the regression analysis, in contrast to female gender (OR=0.31, 95% CI=0.249‒0.386, <i>P</i><0.001) and age (OR=0.951, 95% CI=0.941‒0.962, <i>P</i><0.001), history of heart disease (OR=1.499, 95% CI=1.146‒1.962, <i>P</i>=0.003), history of diabetes (OR=1.523, 95% CI=1.162‒1.995, <i>P</i>=0.002), hypertension (OR=1.241, 95% CI=1.023‒1.506, <i>P</i>=0.029), being overweight or obese (OR=2.192, 95% CI=1.755‒2.737, <i>P</i><0.001), being in the richest or second richest wealth index quantiles (OR=1.315, 95% CI=1.107‒1.156, <i>P</i>=0.002), and increased waist circumference (OR=1.409, 95% CI=1.107‒1.793, <i>P</i><0.005) were independently associated with a higher risk of having NASH.</p><p><strong>Conclusion: </strong>In this study, we determined the prevalence of NASH and found male gender, younger age, history of heart disease, history of diabetes, hypertension, socioeconomic status, and obesity as possible factors associated with a higher risk of NASH among Iranians.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 11","pages":"598-605"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Normal Value of Perfusion Index in Healthy Neonates Born in Iran.","authors":"Maryam Saeedi, Razieh Sangsari, Kayvan Mirnia, Monireh Ghanbari","doi":"10.34172/aim.31293","DOIUrl":"10.34172/aim.31293","url":null,"abstract":"<p><strong>Background: </strong>Perfusion index is a dependable indicator for assessing the perfusion status of newborns. A low perfusion index indicates compromised hemodynamic function. The study aims to investigate perfusion index in asymptomatic newborns aged 35 to 41 weeks who did not require medical support.</p><p><strong>Methods: </strong>Healthy neonates born in four major maternity hospitals of Tehran University from 2019 to 2021 were selected. To ensure consistency and reliability in data collection, a detailed manual was developed and distributed, along with comprehensive training sessions for all personnel involved.</p><p><strong>Results: </strong>A total of 994 newborns entered the study. Among them, echocardiography was adversely affected in 218 neonates due to abnormal screening pulse oximetry. Of these 218 neonates, 53 were found to have abnormal echocardiography results. The median perfusion index value in healthy neonates was 1.6%, and the median oxygen saturation was 97%. A percentile perfusion index curve was developed for healthy neonates to establish a normal reference range.</p><p><strong>Conclusion: </strong>Developing a percentile perfusion index curve specific to healthy neonates provides a useful reference range for healthcare providers to assess perfusion status in this population, but further research is needed to confirm its accuracy.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 11","pages":"606-610"},"PeriodicalIF":1.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Gap Between the Actual Cost and Tariffs of Global Surgical Procedures: A Retrospective Cross-sectional Study in Qazvin Province, Iran.","authors":"Ehsan Zarei, Maedehsadat Hashemi, Pouria Farrokhi","doi":"10.34172/aim.31106","DOIUrl":"10.34172/aim.31106","url":null,"abstract":"<p><strong>Background: </strong>Iran's healthcare system has a significant discrepancy between the national tariff and the cost of global surgical procedures (GSPs). This study aimed to compare the actual costs of GSPs with national tariffs in Iran's public hospitals.</p><p><strong>Methods: </strong>This retrospective cross-sectional study was conducted in 2017. Using the census method, 6126 GSPs performed in three public hospitals were investigated in this study. Additionally, national tariffs from the Supreme Council of Health Insurance were obtained. The tariff-cost gap was the discrepancy between a GSP's actual costs and tariff. Multiple linear regression analysis determined factors affecting the tariff-cost gap.</p><p><strong>Results: </strong>The average actual cost of GSPs was 637 USD, while the average tariff was 495 USD. The reimbursement covered only 78% of the costs. The gap was higher in older (B=1.05, 95% CI: 0.76-1.35, <i>P</i><0.001), females (B=26.7, 95% CI: 15.5-37.9, <i>P</i><0.001), patients with a longer stay (B=81.2, 95% CI: 77.5-84.8, <i>P</i><0.001), and procedures performed by full-time surgeons (B=67.3, 95% CI: 56.9-77.5, <i>P</i><0.001). Furthermore, neurosurgery had the highest effect on forecasting the gap between actual costs and tariffs among surgical specialties (B=346.9, 95% CI: 214.3-479.5, <i>P</i><0.001).</p><p><strong>Conclusion: </strong>Public hospitals suffer from large financial losses due to the national tariff for many GSPs not covering their actual costs. It is suggested that tariffs be increased for certain customer segments that can bear higher costs and global tariffs be adjusted to match actual service delivery costs.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 10","pages":"580-587"},"PeriodicalIF":1.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11532652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Research Trends on Colorectal Cancer (2014-2023): A Scientometric and Visualized Study.","authors":"Iman Menbari Oskouie, Hediyeh Alemi, Naghmeh Khavandgar, Heydar Ali Mardani-Fard, Azadeh AleTaha, Amir-Hossein Mousavian, Ali Rahimi, Mohammad Abdollahi, Akbar Soltani, Amir Kasaeian, Majid Sorouri","doi":"10.34172/aim.31944","DOIUrl":"10.34172/aim.31944","url":null,"abstract":"<p><strong>Background: </strong>Colorectal cancer (CRC) ranks as the third most common cancer worldwide, significantly contributing to cancer-related deaths and increasingly affecting younger populations. Although its impact on patients' quality of life is profound, scientometric studies on CRC remain underexplored. The objective of this study was to evaluate the scientific literature on CRC from 2014 to 2023, employing a range of scientometric and statistical approaches.</p><p><strong>Methods: </strong>This study obtained CRC-related publications from the Scopus database. The analyses of the collaboration and co-occurrence among countries/regions, institutions, journals, references, authors, and keywords were conducted utilizing VOSviewer, facilitating the identification of key research trends and emergent subjects.</p><p><strong>Results: </strong>A review of Scopus entries yielded 200,385 papers on CRC in the last decade, noting a yearly increase in publications from 2014 to 2023. China emerged as the most prolific contributor with 46,674 documents. A positive correlation was identified between a country's CRC research output and gross domestic product (GDP; <i>r</i>=0.961, <i>P</i><0.001). The journal \"Cancers\" led to 3006 articles, and H. Brenner stood out as the foremost author with 452 publications. However, the Ministry of Education of the People's Republic of China led institutional contributions to 3094 papers.</p><p><strong>Conclusion: </strong>With a leading count of 46674 articles, China dominated CRC research, particularly highlighted by the Ministry of Education of the People's Republic of China. The primarily obtained keywords were CRC, cancer, prognosis, rectal cancer, and colon cancer. Despite the presence of global collaborations, there is a pressing need for increased research funding and support in the CRC, especially within developing nations. This study is a navigational tool for medical professionals, researchers, and surgical assistants to grasp the international progress and directions in CRC research.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 10","pages":"563-572"},"PeriodicalIF":1.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11532657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}