Archives of Iranian Medicine最新文献

Voices from the Frontline: Healthcare Workers' Perspectives on Government Health Reforms in Iran. 来自前线的声音：医疗工作者对伊朗政府医疗改革的看法。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2025-07-01 DOI: 10.34172/aim.34341

Ali Dabbagh, Firoozeh Madadi, Mina Fakhrzadegan

{"title":"Voices from the Frontline: Healthcare Workers' Perspectives on Government Health Reforms in Iran.","authors":"Ali Dabbagh, Firoozeh Madadi, Mina Fakhrzadegan","doi":"10.34172/aim.34341","DOIUrl":"10.34172/aim.34341","url":null,"abstract":"Background: The healthcare system is a crucial indicator of government performance, especially in developing countries like the Islamic Republic of Iran, which has seen significant reforms in recent decades. This study explores healthcare workers' perceptions of recent government health policies.Methods: This study was conducted as a national survey. An anonymous questionnaire containing 22 key challenges facing the healthcare sector was distributed via social media to healthcare employees. The aim was to gather insights on the challenges confronting Iran's healthcare system. After collecting the responses, we evaluated and analyzed the data.Results: Over one week, we received responses from 805 healthcare workers. The findings revealed that the following issues were considered as the most important priorities across various categories: the healthcare system's entitlement from the gross national product; addressing the problems of doctors, including their income; preventing migration; combating non-scientific health practices; the challenges of medical education for future healthcare providers (such as reduced career hopes, desires to emigrate, drug use, and mental health issues like suicide); and tackling corruption in the country's pharmaceutical market.Conclusion: The most significant challenges identified were economic issues and the medical education process, from admission to graduation. Notably, as people's ages increased, the scores related to economic challenges and job burnout also rose.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 7","pages":"398-403"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the Clinical and Genetic Spectrum of PMM2-CDG: Insights from a Family with a Novel Variant and Previous Studies. PMM2-CDG临床和遗传谱的研究：来自一个新变异家族和先前研究的见解。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2025-07-01 DOI: 10.34172/aim.34187

Parnian Alagha, Tara Akhtarkhavari, Ebrahim Shokouhian, Fatemeh Ghodratpour, Sanaz Arzhangi, Hossein Najmabadi, Kimia Kahrizi

{"title":"Investigation of the Clinical and Genetic Spectrum of PMM2-CDG: Insights from a Family with a Novel Variant and Previous Studies.","authors":"Parnian Alagha, Tara Akhtarkhavari, Ebrahim Shokouhian, Fatemeh Ghodratpour, Sanaz Arzhangi, Hossein Najmabadi, Kimia Kahrizi","doi":"10.34172/aim.34187","DOIUrl":"10.34172/aim.34187","url":null,"abstract":"Background: PMM2-CDG, also known as congenital disorder of glycosylation type 1a, is the most common N-linked glycosylation disorder, characterized by a wide range of neurological and multisystem manifestations. Understanding the genotype-phenotype correlations is essential for accurate diagnosis and patient management. This study aims to identify the genetic cause of PMM2-CDG in an Iranian family with multiple affected members, and to analyze the genetic and clinical spectrum of the disorder through a comprehensive literature review.Methods: Exome sequencing re-analysis was performed to detect disease-causing variants in three affected siblings. Additionally, a literature review was conducted, analyzing 91 previously reported cases of PMM2-CDG to determine the most prevalent variants and associated clinical features.Results: A novel splice site variant (c.640-9T>A) was identified alongside a previously reported missense mutation (c.647A>T; p.N216I) in the affected individuals. The literature review revealed that the most frequent PMM2 variants were p.R141H (28.8%), p.V231M (12.8%), p.N216I (6.4%), and p.V129M (5.8%), with 77.6% of mutations occurring in exons 5 and 8. The most common clinical findings included developmental delay, ocular abnormalities (hypertelorism, strabismus), muscular system defects (hypotonia, muscle weakness), neurological symptoms (abnormal MRI findings), cardiovascular involvement (pericarditis, pericardial effusion), and clotting disorders.Conclusion: We expect that our detailed clinical study will improve the genotype-phenotype interpretation of causal PMM2-CDG variants and the analysis of next-generation sequencing data, leading to clarification of the cause of complicated cases of rare diseases.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 7","pages":"387-397"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reevaluating Authorship in the Age of AI: The Case Against ChatGPT as a Scientific Co-Author. 在人工智能时代重新评估作者身份：反对ChatGPT作为科学合著者的案例。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2025-07-01 DOI: 10.34172/aim.34214

Masoud Keikha

引用次数: 0

Challenges Faced by Talented Students in Medical Sciences Education: A Phenomenological Study. 医学人才教育面临的挑战：现象学研究

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2025-07-01 DOI: 10.34172/aim.34288

Houra Ashrafifard, Hossein Karimi Moonaghi, Raheleh Gharibnavaz, Eshagh Ildarabadi

{"title":"Challenges Faced by Talented Students in Medical Sciences Education: A Phenomenological Study.","authors":"Houra Ashrafifard, Hossein Karimi Moonaghi, Raheleh Gharibnavaz, Eshagh Ildarabadi","doi":"10.34172/aim.34288","DOIUrl":"10.34172/aim.34288","url":null,"abstract":"Background: Talented students are among the key human resources in society, and educational and university authorities bear the responsibility of addressing the potential challenges they face. Therefore, identifying these challenges is essential. Objective: This research aimed to identify the challenges experienced by talented students and to propose possible solutions to help managers and planners design effective interventions.Methods: The participants were 50 talented students from healthcare sciences. A phenomenological approach was employed using Colaizzi's seven steps method for data collection and analysis. Structured interviews were conducted with the students selected through purposive sampling.Results: Data analysis revealed the central theme of the \"narrow alley of talents\" accompanied by six main themes: \"motivational slope\", \"striving for improvement\", \"uneven university path\", \"social lens\", \"family umbrella\", and \"the bright side of talents\", each comprising several subthemes.Conclusion: The challenges faced by talented students can be mitigated and their competencies enhanced through tailored educational opportunities and services, counseling, and engagement of external motivational and support resources.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 7","pages":"404-411"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global, Regional, and National Burden of Aortic Aneurysm and Its Attributable Risk Factors from 1990 to 2021: An Analysis of the Global Burden of Disease Study 2021. 1990年至2021年全球、地区和国家主动脉瘤负担及其归因风险因素：2021年全球疾病负担研究分析

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2025-07-01 DOI: 10.34172/aim.34264

Huanan Liu, Xiaoshen Zhang, Hua Lu

{"title":"Global, Regional, and National Burden of Aortic Aneurysm and Its Attributable Risk Factors from 1990 to 2021: An Analysis of the Global Burden of Disease Study 2021.","authors":"Huanan Liu, Xiaoshen Zhang, Hua Lu","doi":"10.34172/aim.34264","DOIUrl":"10.34172/aim.34264","url":null,"abstract":"Background: Aortic aneurysm (AA) remains a significant global cause of mortality. This study aimed at systematically revealing the distribution of AA burden and its attributable risk factors from 1990 to 2021.Methods: Data of AA-related deaths, disability-adjusted life years (DALYs), and corresponding age-standardized rates (ASRs) were extracted from the Global Burden of Disease (GBD) 2021 study. Estimated annual percentage change (EAPC) was calculated to assess trends in the AA burden at global, regional, and national levels. The temporal trends of AA burden were analyzed, and key attributable risk factors were identified. Population attributable fractions (PAFs) were calculated to assess the impact of these risk factors.Results: From 1990 to 2021, global AA-related deaths increased by 74.218% (95% UI: 83090‒93492 to 138413‒165739), while age-standardized death rates (ASDR) declined by 26.772% (95% UI: 2.538 to 1.861 per 100000). DALYs rose by 64.944% (95% UI: 1784177‒2006704 to 2857320‒3353858), with ASDALYR falling by 25.1% (95% UI: 48.789 to 36.543 per 100000). Regions with high or middle-high socio-demographic index (SDI) scores experienced higher AA burdens compared to lower SDI regions. Males had higher burdens, peaking at ages 70‒74 (deaths) and 65‒69 (DALYs). In regions with an SDI above 0.75, the ASRs of AA burden exhibited a downward trend. Smoking was identified as the most significant attributable risk factor.Conclusion: From 1990 to 2021, declining trends were observed in the ASRs of AA-related deaths and DALYs, although males reported a higher AA burden than females. Efforts to control tobacco use should be prioritized as a key preventive strategy.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 7","pages":"374-386"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dr. Badri Teymourtash (1908-1995), and her Key Role in Foundation of Mashhad Dental School in Northeastern Iran. Badri Teymourtash博士（1908-1995），她在伊朗东北部马什哈德牙科学校的建立中发挥了关键作用。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2025-07-01 DOI: 10.34172/aim.34229

Hediyeh Toutouni, Shirin Taraz Jamshidi, Ali Emadzadeh

引用次数: 0

Risk Factors and Causes of Inpatient Falls in a Tertiary Care Hospital in Tehran, Iran; A Retrospective Study. 伊朗德黑兰三级医院住院病人跌倒的危险因素和原因回顾性研究。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2025-07-01 DOI: 10.34172/aim.33365

Maryam Ameri, Foroozan Faress, Siamak Soltani, Abbas Aghabiklooei, Leyla Abdolkarimi, Amirmohammad Babaeigoharrizi

{"title":"Risk Factors and Causes of Inpatient Falls in a Tertiary Care Hospital in Tehran, Iran; A Retrospective Study.","authors":"Maryam Ameri, Foroozan Faress, Siamak Soltani, Abbas Aghabiklooei, Leyla Abdolkarimi, Amirmohammad Babaeigoharrizi","doi":"10.34172/aim.33365","DOIUrl":"10.34172/aim.33365","url":null,"abstract":"Inpatient falls are a significant health concern, leading to increased hospital stays, costs, and potential severe injuries or death. This study aims to investigate the incidence, risk factors, and challenges of inpatient falls in Firoozgar hospital . This cross-sectional study was conducted in a tertiary care hospital in Tehran, Iran. The study included all patients who experienced a fall incident in Firoozgar hospital between April 2023 and March 2024. We included 90 patients with an average age of 57.49 years. Falls were more prevalent among men, older patients, and individuals with lower education levels. Underlying conditions such as diabetes, heart disease, and addiction significantly increased the risk of falls. Identifying the specific causes of falls in each hospital ward can facilitate the development of targeted preventive strategies. Implementing environmental modifications and fall prevention measures could substantially reduce fall risks, enhance patient safety, and lower healthcare costs.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 7","pages":"412-415"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial Intelligence in Research: A Double-Edged Sword in Evidence Generation. 研究中的人工智能：证据生成的双刃剑。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2025-07-01 DOI: 10.34172/aim.34419

Seyyed Muhammad Mahdi Mahdavinoor, Seyyed Hatam Mahdavinoor

引用次数: 0

Challenges of Egg, Sperm, and Embryo Donation from the Perspective of Iranian Experts: A Qualitative Study. 从伊朗专家的角度看卵子、精子和胚胎捐赠的挑战：一项定性研究。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2025-06-01 DOI: 10.34172/aim.33938

Mostafa Saeedinia, Shirin Shahbazi Sighaldeh, Kobra Joodaki, Sedigheh Hantoushzadeh, Fedyeh Haghollahi, Saghar Salehpour, Majid Zaki-Dizaji, Nikzad Isazadeh, Zohreh Heidary

{"title":"Challenges of Egg, Sperm, and Embryo Donation from the Perspective of Iranian Experts: A Qualitative Study.","authors":"Mostafa Saeedinia, Shirin Shahbazi Sighaldeh, Kobra Joodaki, Sedigheh Hantoushzadeh, Fedyeh Haghollahi, Saghar Salehpour, Majid Zaki-Dizaji, Nikzad Isazadeh, Zohreh Heidary","doi":"10.34172/aim.33938","DOIUrl":"10.34172/aim.33938","url":null,"abstract":"Background: Assisted reproductive technologies (ARTs) have been implemented in Iran for nearly thirty years. However, except for embryo donation, none of the other cases, including embryo and sperm donation have not yet been legalized through parliamentary resolutions. This study aims to explore the challenges of these three types of donations from the perspective of fertility experts.Methods: This qualitative exploratory research was conducted in Tehran in 2024. Participants consisted of 12 specialists with experience in infertility treatment or other fields related to embryo, sperm and egg donation, who were selected through purposive sampling. Data were collected via focus group discussions and analyzed based on conventional content analysis using MAXQDA 20.Results: Data were classified into 12 categories. Eight categories describe the challenges and problems of egg, sperm, and embryo donation and 4 categories describe the solutions recommended by experts.Conclusion: According to the study findings, sperm donation faces the most legal and medical challenges compared to egg and embryo donation. Designing a comprehensive national protocol could be the best solution proposed to Iranian health policymakers. Conducting more qualitative and mixed methods studies related to sperm, egg, and embryo donation could confirm and strengthen the findings of this study.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 6","pages":"356-366"},"PeriodicalIF":1.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144769404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Candida albicans Aortic Fungus Ball in a Behçet's Disease Patient. 白念珠菌主动脉弓真菌球1例behalet病患者。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2025-06-01 DOI: 10.34172/aim.34305

Murat Tasci, Hasan Tahsin Gozdas, Yunus Yilmazsoy, Songul Peltek Ozer, Kemalettin Erdem

引用次数: 0