Archives of Iranian Medicine最新文献

{"title":"Challenges and Prospects for Surrogacy in Iran as a Pioneer Islamic Country in this Field.","authors":"Mohammad Haddadi, Sedigheh Hantoushzadeh, Parisa Hajari, Roya Rashid Pouraie, Mir Yasha Hadiani, Gholam Reza Habibi, Nasim Eshraghi, Marjan Ghaemi","doi":"10.34172/aim.33920","DOIUrl":"10.34172/aim.33920","url":null,"abstract":"","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 4","pages":"252-254"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12085801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144096037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weight Management Processes and Individual Differences: A Validation Study of P-Weight and S-Weight in Farsi.","authors":"Zahra Gohari Dezfuli, Minoo Hasan Rashedi, Mina Araminejad, Keyvan Karimi, Ensieh Sadat Mansouri, Tohid Seif Barghi, Amir-Hossein Memari","doi":"10.34172/aim.33513","DOIUrl":"https://doi.org/10.34172/aim.33513","url":null,"abstract":"<p><strong>Background: </strong>The obesity epidemic is a growing public health concern, making weight management a crucial aspect of overall health and well-being. Indeed, effective tools to facilitate behavior change are essential for achieving long-term success in managing weight. This study aimed to validate the Farsi versions of the S-weight and P-weight questionnaires to support personalized weight management by assessing specific aspects of psychological readiness, including motivation, self-regulation, emotional reappraisal (EmR), and environmental restructuring (EnR).</p><p><strong>Methods: </strong>A cross-sectional study using self-administered questionnaires was conducted. The study included 455 adults aged 17-65, excluding those undergoing invasive weight-loss interventions. The measured variables included EmR, weight consequence evaluation (WCE), weight management actions (WMA), and EnR, which were assessed using structured Likert-scale questionnaires. Exploratory and confirmatory factor analyses were performed, with reliability evaluated via Cronbach's alpha and intraclass correlation coefficient (ICC). Statistical significance was set at <i>P</i><0.05.</p><p><strong>Results: </strong>The questionnaires showed strong validity and reliability (KMO=0.91; Bartlett's test χ²=3999.75; <i>P</i><0.001). Overweight and obese participants scored significantly higher in change processes than normal-weight participants (<i>P</i><0.001).</p><p><strong>Conclusion: </strong>The validated instruments provide a reliable means of tailoring weight management strategies based on psychological readiness, potentially improving long-term outcomes.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 3","pages":"162-170"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Induced Lactation in Non-gestational Mothers in Iran: Outcomes and Predictors of Breastfeeding Success.","authors":"Seyed Alireza Marandi, Nahid Ezzeddin Zanjani, Mahmood Ravari, Mojgan Mazloom, Ziba Mohammad Khanlou, Amir Kasaeian","doi":"10.34172/aim.33516","DOIUrl":"https://doi.org/10.34172/aim.33516","url":null,"abstract":"<p><strong>Background: </strong>Induced lactation allows non-gestational mothers, such as those adopting or using surrogacy, to breastfeed their children. While widely practiced in various contexts, little research exists on its application in Iran. This study aimed to assess the success and duration of induced lactation in Iranian mothers without prior pregnancy.</p><p><strong>Methods: </strong>This descriptive-analytical study was conducted between 2013 and 2021, recruiting mothers who became parents through surrogacy or adoption. Participants followed a protocol using hormonal (combined oral contraceptives, domperidone) and non-hormonal methods (breast stimulation). Data on breastfeeding duration, exclusivity, and reasons for cessation were collected through regular follow-up. Chi-square tests and multivariable logistic regression were used to assess factors influencing breastfeeding duration.</p><p><strong>Results: </strong>Of the 117 mothers, 100 breastfed for<180 days and 17 for≥180 days. The median breastfeeding duration was significantly longer in the≥180 days group (240 days vs. 30 days, <i>P</i><0.001). Exclusive breastfeeding up to 120 days was much more common in the≥180 days group (70.60% vs. 24%, <i>P</i><0.001) while biological reasons were the primary cause of cessation in both groups but with different frequencies (100% vs. 75%, <i>P</i>=0.022). The results of logistic regression showed that exclusive breastfeeding for 120 days increased the likelihood of successful breastfeeding for≥180 days (OR: 5.72 (1.76‒18.61), <i>P</i>=0.004) adjusting for mother's age (1.02 (0.92‒1.12), <i>P</i>=0.755), duration of Domperidone use (1.01 (0.98‒1.04), <i>P</i>=0.536), duration of LD use (1.04 (0.95‒1.15), <i>P</i>=0.366), and reason for stopping breastfeeding (7.02 (0.39‒125.30), <i>P</i>=0.185).</p><p><strong>Conclusion: </strong>This first Iranian study on induced lactation underscores the role of early exclusive breastfeeding in extending breastfeeding duration. Pharmacological support aids in initiating lactation, but long-term success relies on consistent breastfeeding practices. These findings highlight the need for culturally tailored guidelines and support for non-gestational mothers in Iran.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 3","pages":"135-139"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retro-orbital Metastasis in Chromophobe Renal Cell Carcinoma: A Case Report and Review.","authors":"Tanju Kapagan, Nilufer Bulut, Mehmet Halıcı, Gokmen Umut Erdem","doi":"10.34172/aim.31231","DOIUrl":"https://doi.org/10.34172/aim.31231","url":null,"abstract":"<p><p>Chromophobe renal cell carcinoma (ChRCC) is a rare subtype of renal cell carcinoma (RCC). We present a case of a 61-year-old male with ChRCC who exhibited unusual metastasis to the retro-orbital area, a site rarely affected by RCC. The patient experienced diplopia and proptosis, prompting treatment with sunitinib and palliative radiotherapy. Remarkably, rapid improvement in ocular symptoms was observed following radiotherapy. Despite this localized response, the patient's overall condition deteriorated, highlighting the aggressive nature of ChRCC. This case underscores the importance of considering ChRCC in metastatic presentations and the potential efficacy of local palliative interventions.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 3","pages":"171-173"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Workplace Violence Against Healthcare Professionals in Iran: A Tragic Wake-Up Call.","authors":"Maryam Modabber, Ehsan Shamsi Gooshki","doi":"10.34172/aim.33548","DOIUrl":"https://doi.org/10.34172/aim.33548","url":null,"abstract":"","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 3","pages":"177-179"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Idiopathic Intracranial Hypertension.","authors":"Chun-Chieh Huang, Yu-Fen Wang","doi":"10.34172/aim.33110","DOIUrl":"https://doi.org/10.34172/aim.33110","url":null,"abstract":"","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 3","pages":"174-176"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Risk of Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Among High-risk Deferred Blood Donors, Based on Deferral Reasons.","authors":"Sara Riyahi, Amir Teimourpour, Sedigheh Amini-Kafiabad, Mahtab Maghsudlu, Zohreh Sharifi, Dariush Minai-Tehrani","doi":"10.34172/aim.33374","DOIUrl":"https://doi.org/10.34172/aim.33374","url":null,"abstract":"<p><strong>Background: </strong>Blood donor selection is a crucial stage in reducing the risk of transfusion-transmissible infections (TTIs) and ensuring the safety of blood components. The objective of this study is to evaluate the impact of each question regarding deferral reasons on the risk of TTIs.</p><p><strong>Methods: </strong>This study was conducted in twenty blood transfusion centers between March 1, 2018, and September 30, 2019, including high-risk deferred volunteers from seven different groups. All samples from deferral volunteers were screened for HBsAg, anti-HCV, and HIVAg/Ab. Negative samples were pooled and tested for HBVDNA and HCVRNA. The results were compared with those of eligible donors. The association between high-risk behaviors and TTIs was analyzed using risk ratios and 95% confidence intervals.</p><p><strong>Results: </strong>Out of 2525 high-risk deferred volunteers, the risk of TTIs based on deferral reasons was as follows: a history of positive results of infectious tests RR: 401.6 ( 95% CI : 276.7‒582.8), drug abuse RR: 133.3 (61.9‒287.0), exposure to someone else's blood RR:39.8 (5.7‒275.3), high-risk procedures RR:14.3 (7.9‒25.9), unsafe sexual behaviors RR:9.03 (4.1‒20.1), imprisonment and medical interventions RR=0.0. The deferred group had significantly higher rates of viral markers compared to eligible donors. Furthermore, one reactive HCV RNA was detected in anti-HCV negative samples.</p><p><strong>Conclusion: </strong>This study showed that deferring blood donations based on a history of positive results from infectious tests, drug abuse, unsafe sexual behaviors, exposure to someone else's blood, and high-risk procedures is effective for ensuring blood safety. These deferral practices should be maintained. We recommend that other deferral criteria should be regularly evaluated for effectiveness.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 3","pages":"155-161"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haplogroup Structure and Genetic Variation Analyses of Mitochondrial Genome SNPs in the Iranian Population.","authors":"Masoumeh Ghasemi, Marzieh Mohseni, Zohreh Fattahi, Masoud Edizadeh, Maryam Beheshtian, Fatemeh Keshavarzi, Khadijeh Jalalvand, Mohammadamin Omrani, Ali Khanbazi, Yasser Riazalhosseini, Mohammad Reza Akbari, Kimia Kahrizi, Hossein Najmabadi","doi":"10.34172/aim.33639","DOIUrl":"https://doi.org/10.34172/aim.33639","url":null,"abstract":"<p><strong>Background: </strong>Mitochondrial DNA (mtDNA) is a valuable marker for population studies and forensic investigations. Recent advancements in massively parallel sequencing technologies enable whole mitochondrial genome sequencing. This study collected blood samples from unrelated Iranian participants from four ethnic groups: Persian, Kurd, Lur, and Azeri. We mapped mtDNA haplogroups according to genetic ancestry and investigated the ethnic similarities within the Iranian population.</p><p><strong>Methods: </strong>Complete mtDNA sequences were generated with targeted mtDNA sequencing method and haplogroups were determined on the base of mitogenome polymorphisms. Additionally, we used data from the whole exome sequencing (WES) of the current samples to compare the variants identified by two different mitochondrial testing methods. Principal component analysis (PCA) calculations were performed using the R software to determine diversity between unrelated individuals of various ethnicities.</p><p><strong>Results: </strong>A total of 129 sub-haplogroups were identified in 15 main haplogroups. The findings revealed high frequencies of haplogroups U and H (22.4% and 20.3%, respectively) in the Iranian population. The PCA scatter plots revealed overlapping diversity, with no distinct trends separating the groups in these four groups within the Iranian population. In the present samples, the WES method identified only 57.8% of the variants detected by the targeted mtDNA sequencing method.</p><p><strong>Conclusion: </strong>Variant studies do not show much difference, which indicate a small genetic difference between the central ethnic groups of Iran. Furthermore, comparing the targeted whole mitochondrial genome to mitochondrial data from WES in our study samples highlights the notion that targeted entire mitochondrial genome is a gold standard method for variant detection.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 3","pages":"140-148"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Effects of Norepinephrine and Phenylephrine Infusion in Preventing Hypotension during Spinal Anesthesia for Cesarean Delivery: A Randomized, Double-Blind Clinical Trial.","authors":"Saeed Jalili, Mitra Hojatansari, Somaye Abdollahi Sabet","doi":"10.34172/aim.33931","DOIUrl":"https://doi.org/10.34172/aim.33931","url":null,"abstract":"<p><strong>Background: </strong>Hypotension following spinal anesthesia is one of the most common complications of cesarean delivery, posing significant risks to both maternal and fetal health. The use of vasopressors is a primary method for the prevention and management of hypotension. <b>Objective:</b> This study aimed to compare the efficacy of norepinephrine and phenylephrine infusion in preventing hypotension in patients undergoing cesarean section under spinal anesthesia.</p><p><strong>Methods: </strong>In this randomized, double-blind clinical trial, 90 pregnant women at 37 weeks of gestation scheduled for elective cesarean delivery were randomly assigned to receive either norepinephrine (n=47) or phenylephrine (n=43). The initial infusion rate was set at 5 µg/min for norepinephrine (up to a maximum of 60 mL/min) and 0.5 mg/min for phenylephrine (up to a maximum of 60 mL/min). Hemodynamic parameters, including systolic blood pressure (SBP) and diastolic blood pressure (DBP), mean arterial pressure (MAP), and heart rate, were assessed. Additionally, umbilical cord blood gas values (PACO₂ and pH) at the time of birth were measured. Statistical analysis was performed using SPSS version 18 with descriptive statistics and independent t-tests or Mann-Whitney U tests (<i>P</i>≤0.05).</p><p><strong>Results: </strong>The findings revealed no statistically significant differences between the norepinephrine and phenylephrine groups regarding SBP and DBP, MAP, heart rate, and umbilical cord blood gas values (PACO₂ and pH) at delivery (<i>P</i>≥0.05).</p><p><strong>Conclusion: </strong>Norepinephrine and phenylephrine appear to have similar efficacy in preventing hypotension during cesarean delivery. Clinicians may select either drug based on the patient's clinical conditions and preferences.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 3","pages":"149-154"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rhazes on the Rejection of \"Emission Theory\" of Vision.","authors":"Mojtaba Heydari, Mohammad Reza Talebnejad, Narges Tajik","doi":"10.34172/aim.31205","DOIUrl":"https://doi.org/10.34172/aim.31205","url":null,"abstract":"","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 3","pages":"180-181"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038803/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}