Vitorino Modesto Santos, Andressa Plaça Tedeschi, Laura Campos Modesto
{"title":"Post-traumatic Stress Disorder: A Major Source of Concern Comment on \"Epidemiology of Post-traumatic Stress Disorder in Iranian Population From 2019 to 2024: A Systematic Review and Meta-analysis\".","authors":"Vitorino Modesto Santos, Andressa Plaça Tedeschi, Laura Campos Modesto","doi":"10.34172/aim.33448","DOIUrl":"10.34172/aim.33448","url":null,"abstract":"","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 2","pages":"132-133"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FIB-4 Index Can Predict Mortality in Hospitalized Patients with COVID-19 Infection, Independent of CT Severity Score.","authors":"Faeze Salahshour, Sahar Karimpour Reyhan, Kazem Zendedel, Kiana Seifouri, Monireh Sadat Seyyedsalehi, Parnian Naghavi, Mahsa Abbaszadeh, Alireza Esteghamati, Manouchehr Nakhjavani, Soghra Rabizadeh","doi":"10.34172/aim.33514","DOIUrl":"10.34172/aim.33514","url":null,"abstract":"<p><strong>Background: </strong>The fibrosis 4 (FIB-4) index is typically used in assessing liver fibrosis, and has shown potential in predicting the outcome in various diseases. This study aims to evaluate the predictive power of the FIB-4 index for mortality in COVID-19 patients admitted to a reference hospital in Tehran, Iran.</p><p><strong>Methods: </strong>In this prospective cohort study, 387 patients with COVID-19 without diabetes, were categorized into deceased and surviving groups. We compared anthropometric and demographic data, liver function tests, CT scores, and FIB-4 indices between the groups. Multivariate logistic regression assessed the independent association of FIB-4 with mortality.</p><p><strong>Results: </strong>Among the 387 patients, (all non-diabetics), 58 (15%) died, with a higher mortality rate observed in patients with a FIB-4 index≥2.6 (63.4%) compared to those with FIB-4<2.6 (29.7%). Deceased patients were considerably older and more likely to be hypertensive (<i>P</i> values<0.001). After adjustment of confounding factors, a FIB-4 index≥2.6 was found to be independently associated with increased mortality (OR: 13.511, 95% CI: 1.356-134.580, <i>P</i>=0.026).</p><p><strong>Conclusion: </strong>The FIB-4 index, calculable by routine laboratory tests, may be a valuable prognostic factor for COVID-19 mortality. This easily obtainable marker could help identify high-risk patients early, potentially allowing for more rapid intervention and treatment prioritization.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 2","pages":"88-94"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Conventional Detection to Point-of-care Tests (POCT) Method for Pediatric Respiratory Infections Diagnosis: A Systematic Review.","authors":"Reza Azizian, Setareh Mamishi, Erfaneh Jafari, Mohammad Reza Mohammadi, Fereshteh Heidari Tajabadi, Babak Pourakbari","doi":"10.34172/aim.33505","DOIUrl":"10.34172/aim.33505","url":null,"abstract":"<p><p>Bacterial respiratory infections pose significant health risks to children, particularly infants susceptible to upper respiratory tract infections (URTIs). The COVID-19 pandemic has further exacerbated the prevalence of these infections, with pathogens such as <i>Mycoplasma pneumoniae, Streptococcus pneumoniae, Legionella pneumophila, Staphylococcus aureus, Haemophilus influenzae,</i> and <i>Klebsiella species</i> commonly implicated in pediatric cases. The critical need for accurate and timely detection of these bacterial agents has highlighted the importance of advanced diagnostic techniques, including multiplex real-time PCR, in clinical practice. Multiplex real-time polymerase chain reaction (PCR) offers several advantages, including rapid results, high sensitivity, and specificity. By accelerating the diagnostic process, this approach enables early intervention and targeted treatment, ultimately improving patient outcomes. In addition to PCR technologies, rapid and point-of-care testing (POCT) play a crucial role in the prompt diagnosis of bacterial respiratory infections. These tests are designed to be user-friendly, sensitive, and deliver quick results, making them particularly valuable in urgent clinical settings. POCT tests are often categorized into two main groups: those aimed at determining the cause of infection and those focused on confirming the presence of specific pathogens. By utilizing POCT, healthcare providers can make rapid and informed treatment decisions, leading to more effective management of bacterial respiratory infections in children. As the medical community continues to explore innovative diagnostic approaches, the integration of molecular and rapid testing methods offers significant promise in the realm of bacterial respiratory infections. By adopting these cutting-edge technologies, healthcare professionals can enhance their ability to accurately diagnose these infections, tailor treatment strategies, and ultimately improve patient care.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 2","pages":"112-123"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmad Delbari, Mehrdad Farrokhi, Ahmad Mehri, Mehran Saberian, Mohadeseh Sadri, Mohammad Saatchi
{"title":"Prevalence and Factors Associated with Kidney Stones in the Elderly Iranian Population: Findings from the Ardakan Cohort Study on Aging (ACSA).","authors":"Ahmad Delbari, Mehrdad Farrokhi, Ahmad Mehri, Mehran Saberian, Mohadeseh Sadri, Mohammad Saatchi","doi":"10.34172/aim.33337","DOIUrl":"10.34172/aim.33337","url":null,"abstract":"<p><strong>Background: </strong>The incidence of kidney stones has been rising globally, particularly among the elderly. This study aims to determine the prevalence of kidney stones and its associated factors in Iran.</p><p><strong>Methods: </strong>This cross-sectional study was conducted using the data collected in the first phase of Ardakan Cohort Study on individuals aged 50 years and above, in the Yazd province, Iran. Baseline data was collected using a comprehensive checklist and kidney stone occurrence was ascertained through participants' self-reported response to the question \"Have you ever been diagnosed with kidney stones?\" Logistic regression analysis was used due to the binary nature of the outcome.</p><p><strong>Results: </strong>Period prevalence of kidney stone was 22.79 (95% CI=19.41 to 24.12). Thus, out of the total sample of 4,884 individuals, 1113 participants had a history of kidney stones. Among these, 412 (37%) were female and 701 (63%) were male. Significant associations were observed between a history of kidney stones and factors such as self-reported poor health, alcohol consumption, dysuria, higher education level, male gender, and presence of calcium oxalate crystals.</p><p><strong>Conclusion: </strong>This study shows the high prevalence of kidney stones compared to other studies. Considering the relationship between kidney stones and some preventable disorders in the elderly, such as high blood pressure and alcohol consumption, it seems that paying attention to kidney stone disorders can be part of preventive health and treatment interventions for this population group.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 2","pages":"73-80"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tarannom Mohammadtaghi Kashi, Mohammad Taher Hojjati, Ali Asghar Ayatollahi
{"title":"Blood Product Management: A Comprehensive Analysis in a Trauma Center Hospital.","authors":"Tarannom Mohammadtaghi Kashi, Mohammad Taher Hojjati, Ali Asghar Ayatollahi","doi":"10.34172/aim.31324","DOIUrl":"10.34172/aim.31324","url":null,"abstract":"<p><strong>Background: </strong>Today, excessive demand for blood products is a common issue across various medical departments. This demand can lead to improper distribution, waste of blood products, and poor availability for emergency patients. Additionally, it increases costs and the workload of blood banks, disrupting the proper distribution of products among medical centers. Ultimately, all these factors contribute to a decrease in the quality of blood products. This study was conducted to investigate the pattern of blood requests and utilization at 5-Azar Educational Hospital in the Golestan province in 2022.</p><p><strong>Methods: </strong>This cross-sectional study was conducted from June to August 2022. The study population comprised all patients who requested blood product reservations upon admission to the hospital.</p><p><strong>Results: </strong>In the present study, 514 patients with requests for blood product reservations were included, resulting in 739 cross-matches and ultimately 677 transfusions. The cross-match to transfusion (C/T) ratio for this study was 1.09, while the probability of transfusion (T %) was 91.6%. The highest incidence of blood reservation wastage was associated with the neurosurgery department.</p><p><strong>Conclusion: </strong>By addressing the identified challenges and promoting adherence to guidelines, healthcare institutions can improve patient outcomes and ensure responsible use of blood resources.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 2","pages":"107-111"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julija Cvetković, Maja Jovičić Milentijević, Nikola Živković, Miodrag Đorđević, Jelena Grujović, Goran Radenković
{"title":"Lactating Adenoma in Pregnancy: Report of Three Cases.","authors":"Julija Cvetković, Maja Jovičić Milentijević, Nikola Živković, Miodrag Đorđević, Jelena Grujović, Goran Radenković","doi":"10.34172/aim.28751","DOIUrl":"10.34172/aim.28751","url":null,"abstract":"<p><strong>Background: </strong>Lactating adenoma is an infrequent benign stromal breast tumor mostly seen during pregnancy and lactation. This report seeks to enhance the literature by presenting three cases diagnosed with this condition, while also highlighting its histological subtypes, immunohistochemical characteristics, and differential diagnoses. <b>Case Presentation:</b> In all three patients, a circumscribed, painless, and mobile mass was found in the breast in the third trimester of pregnancy. Pathohistological examination revealed hyperplastic lobules with glandular formations in back-to-back arrangements showing more or less abundant hobnailing phenomena with intraluminal eosinophilic secretions and inconspicuous myoepithelial cell layer separated by fibrovascular stroma. The immune profile showed positive reaction for cytokeratin 14 and p40 markers, indicating the presence of myoepithelial cells and distinguishing these cases from other breast lesions.</p><p><strong>Conclusion: </strong>Pathohistological and immunohistochemical analysis should be performed to differentiate these lesions from other benign lesions and malignant tumors.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 2","pages":"124-128"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Niloofar Bazazzadegan, Mojgan Babanejad, Susan Banihashemi, Sanaz Arzhangi, Kimia Kahrizi, Kevin Ta Booth, Hossein Najmabadi
{"title":"A Novel Candidate Gene <i>MACF1</i> is Associated with Autosomal Dominant Non-syndromic Hearing Loss in an Iranian Family.","authors":"Niloofar Bazazzadegan, Mojgan Babanejad, Susan Banihashemi, Sanaz Arzhangi, Kimia Kahrizi, Kevin Ta Booth, Hossein Najmabadi","doi":"10.34172/aim.31746","DOIUrl":"10.34172/aim.31746","url":null,"abstract":"<p><p>Cytoskeletal dynamics, the interplay of actin, microtubules, and septins, is a highly coordinated and tightly regulated process. Defects in the proteins involved can result in a wide range of cellular consequences. Hearing loss is the most common sensory defect and exhibits extraordinary genetic and phenotypic heterogeneity. Currently, there are more than 170 genes casually linked to non-syndromic hearing loss (NSHL), of which more than 60 are associated with autosomal dominant inheritance. Here, we add to this growing number by implicating <i>MACF1</i> (OMIM # 608271), as a novel candidate gene for autosomal dominant non-syndromic hearing loss (ADNSHL). MACF1's cytoskeleton integrator function and hair cell expression pattern lead one to believe that it is a necessary protein for hair cells. Many protein domains in MACF1 allow for dynamic interaction with the cytoskeleton. A large Iranian family segregating progressive ADNSHL was recruited for this study. The proband had bilateral mild-moderate sensorineural hearing loss and was negative for <i>GJB2</i> mutations. After applying exome sequencing on the proband, a missense mutation c.1378C>T (p.His460Tyr) was found in <i>MACF1</i> and co-segregated with the hearing loss in the extended family. We speculated that <i>MACF1</i> mutations probably cause non-syndromic hearing loss inherited in an autosomal dominant manner. The potential functional impact of the identified variant will be investigated through further analysis.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 1","pages":"63-66"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11862395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Sait Ozsoy, Cem Ilgin Erol, Muhammet Ali Aydemir, Hakan Baysal, Fatih Buyuker, Hatice Seneldir, Ozgur Ekinci, Tunc Eren, Orhan Alimoglu
{"title":"Gastroenteropancreatic Neuroendocrine Tumors: Does Tumor Location Affect Prognosis?","authors":"Mehmet Sait Ozsoy, Cem Ilgin Erol, Muhammet Ali Aydemir, Hakan Baysal, Fatih Buyuker, Hatice Seneldir, Ozgur Ekinci, Tunc Eren, Orhan Alimoglu","doi":"10.34172/aim.33366","DOIUrl":"10.34172/aim.33366","url":null,"abstract":"<p><strong>Background: </strong>Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare entities. Generally, they can be localized anywhere in the gastrointestinal or hepatobiliary tract. The purpose of our study is to evaluate the effect of tumor location on prognosis in patients with GEP-NET undergoing surgery. Our secondary objective is to examine other factors affecting the prognosis of patients with GEP-NET.</p><p><strong>Methods: </strong>We retrospectively analyzed data from 30 patients with GEP-NET who underwent surgery in the General Surgery Clinic between 2012 and 2022. The gNET group (n=18) included tumors located in the gastrointestinal tract, while the pNET group (n=12) included tumors located in the hepatopancreatobiliary system. Surgical, laboratory, radiological, and pathological findings of the patients, as well as follow-up outcomes were recorded and statistically analyzed.</p><p><strong>Results: </strong>In subgroup comparison, tumor size was found to be larger in the pNET group (<i>P</i>=0.002). The statistical analysis of recurrence (16.7% versus 33.3%) and mortality rates (16.7% versus 41.7%) between the subgroups (<i>P</i>=0.329 and <i>P</i>=0.210, respectively) did not reveal a significant difference. When all patients were evaluated, it was observed that advanced age, presence of carcinoma diagnosis, higher tumor grade, advanced TNM stage, larger tumor size, presence of lymphovascular or perineural invasion, elevated mitotic index, higher Ki-67 index, and having received adjuvant therapy increased the rates of recurrence and mortality.</p><p><strong>Conclusion: </strong>There was no statistically significant difference in survival outcomes between the GEP-NET groups located in the gastrointestinal tract and the hepatopancreatobiliary system.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 1","pages":"29-39"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11862391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prognostic Features for Overall Survival in Male Diabetic Patients Undergoing Hemodialysis Using Elastic Net Penalized Cox Regression; A Machine Learning Approach.","authors":"Mehrdad Sharifi, Razieh Sadat Mousavi-Roknabadi, Vahid Ebrahimi, Robab Sadegh, Afsaneh Dehbozorgi, Seyed Rouhollah Hosseini-Marvast, Mojtaba Mokdad","doi":"10.34172/aim.27746","DOIUrl":"10.34172/aim.27746","url":null,"abstract":"<p><strong>Background: </strong>Diabetics constitute a significant percentage of hemodialysis (HD) patients with higher mortality, especially among male patients. A machine learning algorithm was used to optimize the prediction of time to death in male diabetic hemodialysis (MDHD) patients.</p><p><strong>Methods: </strong>This multicenter retrospective study was conducted on adult MDHD patients (2011-2019) from 34 HD centers affiliated with Shiraz University of Medical Sciences. As a special type of machine learning approach, an elastic net penalized Cox proportional hazards (EN-Cox) regression was used to optimize a predictive regression model of time to death. To maximize the generalizability and simplicity of the final model, the backward elimination method was used to reduce the estimated predictive model to its core covariates.</p><p><strong>Results: </strong>Out of 442 patients, 308 eligible cases were used in the final analysis. Their death proportion was estimated to be 28.2%. The estimated overall one-, two-, three-, and eight-year survival rates were 87.6%, 74.4%, 67.2%, and 53.9%, respectively. The EN-Cox regression model retained 14 (out of 35) candidate predictors of death. Five variables were excluded through backward elimination technique in the next step. Only 6 of the remaining 9 variables were statistically significant at the level of 5%. Body mass index (BMI)<25 kg/m<sup>2</sup> (HR=2.75, <i>P</i><0.001), vascular access type (HR=2.60, <i>P</i><0.001), systolic blood pressure (1.02, <i>P</i>=0.003), hemoglobin (11≤Hb≤12.5 g/dL: HR=3.00, <i>P</i>=0.028 and Hb<11 g/dL: HR=2.95, <i>P</i>=0.021), dialysis duration in each session≥4hour (HR=2.95, <i>P</i><0.001), and serum high-density lipoprotein cholesterol (HDL-C) (HR=1.02, <i>P</i>=0.022) had significant effects on the overall survival (OS) time.</p><p><strong>Conclusion: </strong>Anemia, hypotension, hyperkalemia, having central venous catheter (CVC) as vascular access, a longer dialysis duration in each session, lower BMI and HDL-C were associated with lower mortality in MDHD patients.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 1","pages":"9-17"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11862393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prognostic Impact of Right Ventricular Diastolic Dysfunction in Patients Undergoing Isolated Coronary Artery Bypass Grafting.","authors":"Tahereh Davarpasand, Arezoo Zoroufian, Rezvan Ahmadi Roknabadi, Mohammad Sadeq Najafi, Zahra Karimi, Soheil Mansourian, Amirhossein Poopak, Roozbeh Narimani-Javid","doi":"10.34172/aim.28830","DOIUrl":"10.34172/aim.28830","url":null,"abstract":"<p><strong>Background: </strong>Right ventricular diastolic dysfunction (RVDD) increases the volume load on the right ventricle. We aimed to evaluate the association of RVDD with perioperative outcomes in patients undergoing isolated coronary artery bypass graft surgery (CABG).</p><p><strong>Methods: </strong>This single-center observational study included all consecutive isolated CABG patients with a left ventricular ejection fraction (LVEF)>40% from May 2022 to May 2023 who were evaluated for RV diastolic function by transthoracic echocardiography. We divided patients into two groups, with and without RVDD, and then compared the two groups in terms of the primary outcomes of the duration of hospitalization, intensive care unit (ICU) stay, and intubation time, and the secondary outcome composed of postoperative in-hospital complications.</p><p><strong>Results: </strong>Our study found that 49.1% of patients suffered from RVDD, and patients with RVDD had significantly lower systolic blood pressure and were more likely to take angiotensin-converting enzyme inhibitors than those without RVDD. There was no association between RVDD and primary outcomes of hospitalization time (β=-0.01; 95% CI -0.05, 0.04; <i>P</i> value=0.717), ICU stay (β=0.01; 95% CI -0.18, 0.17; <i>P</i> value=0.984) and intubation time ([β=0.06; 95% CI -0.05, 0.17; <i>P</i> value=0.309). However, more postoperative complications occurred in patients with RVDD (90% vs. 85%). After adjustment for confounding factors, RVDD was not independently associated with primary and secondary outcomes.</p><p><strong>Conclusion: </strong>Preexisting RVDD in CABG patients with LVEF>40% increased postoperative complications but not significantly. More extensive studies are needed to evaluate RV diastolic function before cardiac surgery to identify high-risk patients and optimize their perioperative management.</p>","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"28 1","pages":"18-23"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11862402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}