Archives of Iranian Medicine最新文献_第5页

Dr. Ahmad Madani (1946-2024), Eminent Medical Teacher at the Shiraz School of Medicine. 艾哈迈德-马达尼博士（1946-2024 年），设拉子医学院著名医学教师。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2024-08-01 DOI: 10.34172/aim.31286

Mohammad Hossein Azizi

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Prevalence of Certain Corneal Conditions and their Demographic Risk Factors; Tehran Geriatric Eye Study. 某些角膜疾病的患病率及其人口风险因素；德黑兰老年眼科研究。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2024-08-01 DOI: 10.34172/aim.28831

Alireza Hashemi, Hassan Hashemi, Mohammadreza Aghamirsalim, Alireza Jamali, Mehdi Khabazkhoob

{"title":"Prevalence of Certain Corneal Conditions and their Demographic Risk Factors; Tehran Geriatric Eye Study.","authors":"Alireza Hashemi, Hassan Hashemi, Mohammadreza Aghamirsalim, Alireza Jamali, Mehdi Khabazkhoob","doi":"10.34172/aim.28831","DOIUrl":"10.34172/aim.28831","url":null,"abstract":"Background: Corneal abnormalities are one of the important reasons for visual impairment. There is little evidence of the prevalence of different types of corneal abnormalities. The aim of this study was to assess the prevalence of various corneal abnormalities and identify the key risk factors associated with these abnormalities in an elderly population residing in Tehran.Methods: The Tehran Geriatric Eye Study (TGES) was conducted as a cross-sectional study, utilizing a population-based approach and employing stratified cluster random sampling. The study focused on individuals aged 60 years and above residing in Tehran. An ophthalmologist performed a slit lamp examination to evaluate the eyelid, cornea, and crystalline lens.Results: The prevalence of posterior embryotoxon (PE), punctate epithelial defect (PED), pigment on endothelium (POE), corneal dystrophy (CDys), corneal vascularization (CV), and corneal degeneration (CDeg) were estimated to be 0.08% (95% confidence interval [CI]: 0.02 to 0.40), 8.77% (95% CI: 6.64 to 11.51), 0.57% (95% CI: 0.33 to 0.98), 0.53% (95% CI: 0.33 to 0.82), 0.95% (95% CI: 0.60 to 1.52), and 44.87% (95% CI: 41.80 to 47.98), respectively. Overall, approximately 49.08% of the participants exhibited some form of corneal abnormality in at least one eye. The multiple logistic regression model revealed that increasing age was significantly associated with PED, CV, and CD. Furthermore, illiterate participants had a significantly higher prevalence of PE.Conclusion: The findings of this study indicate that approximately half of the elderly population aged 60 years and above in Tehran have at least one corneal abnormality, with corneal degeneration being the most prevalent. Age was identified as the primary determinant of corneal abnormalities.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 8","pages":"414-420"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11416701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Pheochromocytoma/Paraganglioma Syndrome Type 1 Presenting with Atypical Symptoms and a Novel Pathogenic Variant in the SDHD Gene: A Case Report. 表现为非典型症状和 SDHD 基因新型致病变异的嗜铬细胞瘤/巴拉干酪瘤综合征 1 型：病例报告。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2024-08-01 DOI: 10.34172/aim.28810

Elham Zohrehvand, Nastaran Injinari, Maryam Kiani Feyzabadi, Kazem Aghili, Farahnaz Ghaemi, Reyhaneh Azizi

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Comments on "Effects of Patient and Tumor Characteristics on Central Lymph Node Metastasis in Papillary Thyroid Cancer: a Guide for Selective Node Dissection". 就 "患者和肿瘤特征对甲状腺乳头状癌中央淋巴结转移的影响：选择性结节切除指南 "发表评论。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2024-08-01 DOI: 10.34172/aim.27317

Hadi Raeisi Shahraki

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Potentiation of Imipramine-Induced Anti-hyperalgesic and Anti-Nociceptive Effects by Citicoline in the Sciatic Nerve Ligated Mice. 西替考林对坐骨神经结扎小鼠中丙咪嗪诱导的抗过痛和抗痛觉效应的增效作用

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2024-08-01 DOI: 10.34172/aim.28772

Negar Raissi-Dehkordi, Nastaran Raissi-Dehkordi, Bardia Hajikarimloo, Fatemeh Khakpai, Moammad-Reza Zarrindast

{"title":"Potentiation of Imipramine-Induced Anti-hyperalgesic and Anti-Nociceptive Effects by Citicoline in the Sciatic Nerve Ligated Mice.","authors":"Negar Raissi-Dehkordi, Nastaran Raissi-Dehkordi, Bardia Hajikarimloo, Fatemeh Khakpai, Moammad-Reza Zarrindast","doi":"10.34172/aim.28772","DOIUrl":"10.34172/aim.28772","url":null,"abstract":"Background: Peripheral neuropathic pain is a result of damage/illness of the peripheral nerves. The mechanisms caused by its pathophysiology are not completely understood.Methods: Imipramine is a tricyclic antidepressant that is sometimes used to treat neuropathic pain. Moreover, citicoline is considered a novel adjuvant for painful disorders such as neuropathic pain. So, a possible interaction between imipramine and citicoline on pain behavior was examined in nerve-ligated mice using tail-flick and hot plate tests.Results: The results indicated that induction of neuropathic pain by sciatic nerve ligation caused hyperalgesia in nerve-ligated mice. On the other hand, intraperitoneal (i.p.) administration of citicoline (50, 75, and 100 mg/kg), and imipramine (2.5 and 5 mg/kg) induced anti-hyperalgesic and anti-nociceptive effects in nerve-ligated mice. Furthermore, citicoline potentiated the anti-hyperalgesic and anti-nociceptive effects of imipramine when they were co-administrated in nerve-ligated mice. Interestingly, there was an additive effect between imipramine and citicoline upon induction of anti-hyperalgesic and anti-nociceptive effects in nerve-ligated mice.Conclusion: Therefore, it can be concluded that citicoline (as an adjuvant substance) enhanced the efficacy of imipramine for the modulation of pain behavior in nerve-ligated mice.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 8","pages":"456-464"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11416695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Pattern of Participation in Colorectal Cancer Screening from a Population-Based Screening Program in Iran. 伊朗民众参与大肠癌筛查计划的模式。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2024-08-01 DOI: 10.34172/aim.31072

Farimah Rahimi, Reza Rezayatmand, Elaheh Najafi, Zahra Ravankhah, Elham Tabesh, Peyman Adibi

{"title":"Pattern of Participation in Colorectal Cancer Screening from a Population-Based Screening Program in Iran.","authors":"Farimah Rahimi, Reza Rezayatmand, Elaheh Najafi, Zahra Ravankhah, Elham Tabesh, Peyman Adibi","doi":"10.34172/aim.31072","DOIUrl":"10.34172/aim.31072","url":null,"abstract":"Background: In Isfahan, the fecal immunochemical test (FIT) has been used since January 2016 as part of the Iran's Package of Essential Non-communicable Diseases (IraPEN) program for colorectal cancer (CRC) screening. The test is recommended for people who are 50-70 years old. Then, those with positive results would be referred for colonoscopy. This study aims to describe the uptake of the program and its outcome.Methods: A retrospective observational study was performed by collecting data from Isfahan Vice-Chancellor for Health database for this study purpose. The number of participators, the number of positive FIT, and the number of detected polyps or cancers were determined.Results: Between 2016 and 2019, the number of participants in the program reached 345 207 individuals (nearly 40% of the eligible population of 874 674). Totally, 21 264 participants (6.1%) had positive tests, of whom about 20% underwent the recommended colonoscopy with available reports, and 971 (24%) and 110 (3%) patients were diagnosed with polyps and CRC, respectively.Conclusion: Over four years of screening with FIT in Isfahan, 40% of the eligible population participated. Among those with positive FIT results, 20% underwent colonoscopy, and approximately 26% of these individuals were identified as having polyps or cancer. This study provides valuable insights into the uptake and outcomes of a population-based CRC screening program in Isfahan, Iran. The findings highlight the need for targeted interventions to increase participation rates and improve the detection of polyps and CRC cases.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 8","pages":"407-413"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11416694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing the Predictive Value of SOFA and SIRS for Mortality in the Early Hours of Hospitalization of Sepsis Patients: A Systematic Review and Meta-analysis. 比较 SOFA 和 SIRS 对败血症患者住院早期死亡率的预测价值：系统回顾与元分析》。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2024-08-01 DOI: 10.34172/aim.28567

Mahdi Majidazar, Farzaneh Hamidi, Nazanin Masoudi, Zahra Vand-Rajabpour, Seyed Pouya Paknezhad

{"title":"Comparing the Predictive Value of SOFA and SIRS for Mortality in the Early Hours of Hospitalization of Sepsis Patients: A Systematic Review and Meta-analysis.","authors":"Mahdi Majidazar, Farzaneh Hamidi, Nazanin Masoudi, Zahra Vand-Rajabpour, Seyed Pouya Paknezhad","doi":"10.34172/aim.28567","DOIUrl":"10.34172/aim.28567","url":null,"abstract":"Background: Sepsis, a deadly infection causing organ failure and Systemic Inflammatory Response Syndrome (SIRS), is detected early in hospitalization using the SIRS criteria, while sequential organ failure (SOFA) assesses organ failure severity. A systematic review and meta-analysis was evaluated to investigate the predictive value of the SIRS criteria and the SOFA system for mortality in early hospitalization of sepsis patients.Methods: Inclusion criteria were full reports in peer-reviewed journals with data on sepsis assessment using SOFA and SIRS, and their relationship with outcomes. For quality assessment, we considered study population, sepsis diagnosis criteria, and outcomes. The area under the curve (AUC) of these criteria was extracted for separate meta-analysis and forest plots.Results: Twelve studies met the inclusion criteria. The studies included an average of 56.1% males and a mean age of 61.9 (±6.1) among 32,979 patients. The pooled AUC was 0.67 (95% CI: 0.60-0.73) for SIRS and 0.79 (95% CI: 0.73-0.84) for SOFA. Significant heterogeneity between studies was indicated by an I2 above 50%, leading to a meta-regression analysis. This analysis, with age and patient number as moderators, revealed age as the major cause of heterogeneity in comparing the predictive value of the SOFA score with SIRS regarding the in-hospital mortality of sepsis patients (P<0.05).Conclusion: The SOFA score outperformed the SIRS criteria in predicting mortality, emphasizing the need for a holistic approach that combines clinical judgment and other diagnostic tools for better patient management and outcomes.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 8","pages":"439-446"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11416697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Affecting Brain Drain and a Solution to Reduce it in Iran's Health System: A Qualitative Study. 影响伊朗卫生系统人才流失的因素及减少人才流失的解决方案：定性研究。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2024-08-01 DOI: 10.34172/aim.28863

Mohadeseh Ghanbari-Jahromi, Milad Ahmadi Marzaleh

{"title":"Factors Affecting Brain Drain and a Solution to Reduce it in Iran's Health System: A Qualitative Study.","authors":"Mohadeseh Ghanbari-Jahromi, Milad Ahmadi Marzaleh","doi":"10.34172/aim.28863","DOIUrl":"10.34172/aim.28863","url":null,"abstract":"Background: Brain drain is an issue of concern in developing countries. Many factors are involved in this issue, and their identification can be a good guide for decision-makers at different management levels. Therefore, the present study was carried out to identify the factors affecting brain drain and solutions to reduce it in Iran's health system.Methods: The data for this qualitative study was collected in 2023 through 15 semi-structured interviews with Iranian health experts and emigrant elites. Interviews were collected both face-to-face and virtually (on Skype and Google Meet) and analyzed using the thematic content analysis method.Results: Data analysis of the factors affecting brain drain in Iran's health system yielded seven main categories and 45 subcategories. The main categories were \"individual factors,\" \"economic factors,\" \"social and cultural factors,\" \"organizational and administrative factors,\" \"political factors,\" \"attraction factors for destination countries,\" and \"attraction factors of destination countries for elites.\" Also, the solutions were divided into four categories of \"economic,\" \"social,\" \"organizational and scientific,\" and \"political\" factors and 19 subcategories.Conclusion: Due to the increase in brain drain in recent years, it is necessary to make a serious decision in dealing with this issue. Solutions such as creating stable economic conditions, creating an atmosphere of hope, increasing respect and dignity for elite students by politicians, using the elites in macro-decisions, and creating the job rank for honorary professors can lead to reducing brain drain and decreasing the costs of the health system.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 8","pages":"427-438"},"PeriodicalIF":1.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11416693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Data Consistency of Two National Registries in Iran: A Preliminary Assessment to Health Information Exchange. 伊朗两个国家登记处的数据一致性：对健康信息交换的初步评估。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2024-07-01 DOI: 10.34172/aim.30023

Mohammad Dashtkoohi, Mohammad Poursalehian, Zahra Azadmanjir, Masoomeh Vaeidi, Mahdi Mohammadzadeh, Mahdi Sharif-Alhoseini, Khatereh Naghdi, Marzieh Moniri Asl, James Harrop, Vafa Rahimi-Movaghar

{"title":"Data Consistency of Two National Registries in Iran: A Preliminary Assessment to Health Information Exchange.","authors":"Mohammad Dashtkoohi, Mohammad Poursalehian, Zahra Azadmanjir, Masoomeh Vaeidi, Mahdi Mohammadzadeh, Mahdi Sharif-Alhoseini, Khatereh Naghdi, Marzieh Moniri Asl, James Harrop, Vafa Rahimi-Movaghar","doi":"10.34172/aim.30023","DOIUrl":"10.34172/aim.30023","url":null,"abstract":"Background: The National Spinal Cord Injury Registry of Iran (NSCIR-IR) and the National Trauma Registry of Iran (NTRI) were established to meet the data needs for research and assessing trauma status in Iran. These registries have a group of patients shared by both registries, and it is expected that some identical data will be collected about them. A general question arises whether the spinal cord injury registry can receive part of the common data from the trauma registry and not collect them independently.Methods: We examined variables captured in both registries based on structure and concept, identified the overlapping period during which both systems recorded data in the same centers and extracted relevant data from both registries. Further, we evaluated the data for any discrepancies in amount or nature and pinpointed the underlying reasons for any inconsistencies.Results: Out of all the variables in the NSCIR-IR database, 18.6% of variables were similar to the NTRI in terms of concept and structure. Although four hospitals participated in both registries, only two (Sina and Beheshti Hospitals) had common cases. Patient names, prehospital intubation, ambulance arrival time, ICU length of stay, and admission time were consistent across both registries with no differences. Other common data variables had significant discrepancies.Conclusion: This study highlights the potential for health information exchange (HIE) between NSCIR-IR and NTRI and serves as a starting point for stakeholders and policymakers to understand the differences between the two registries and work toward the successful adoption of HIE.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 7","pages":"357-363"},"PeriodicalIF":1.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Trans-Anal Endorectal Pull-Through Outcomes in Hirschsprung's Disease in Different Age Groups: A Comprehensive Systematic Review. 不同年龄组经肛门直肠牵拉术治疗赫氏胃肠病的效果评估：全面系统回顾。

IF 1 4区医学

Archives of Iranian Medicine Pub Date : 2024-07-01 DOI: 10.34172/aim.28183

Farshid Ghasemi Meidansar, Mohammad Moradi, Seyed Ali Nabipoorashrafi, Seyyed Javad Nasiri, Tahereh Chavoshi, Mohammad Aldraji, Fariba Jahangiri

{"title":"Evaluation of Trans-Anal Endorectal Pull-Through Outcomes in Hirschsprung's Disease in Different Age Groups: A Comprehensive Systematic Review.","authors":"Farshid Ghasemi Meidansar, Mohammad Moradi, Seyed Ali Nabipoorashrafi, Seyyed Javad Nasiri, Tahereh Chavoshi, Mohammad Aldraji, Fariba Jahangiri","doi":"10.34172/aim.28183","DOIUrl":"10.34172/aim.28183","url":null,"abstract":"Background: The timing of trans-anal endorectal pull-through (TAEPT) for Hirschsprung's disease (HD) is controversial. Early endorectal pull-through avoids the occurrence of preoperative enterocolitis. However, delayed pull-through (≥31 days) enables postnatal maturation of the anal canal and sphincter complex. The aim of this study was to identify the best age to perform trans-anal pull-through according to the literature.Methods: This is a comprehensive systematic review. All articles published from 2010 to 2022 were searched in the Web of Science, Ovid Medline, PubMed, CINAHIL, and Embase databases, using the keywords HD, delayed or early treatment, trans-anal pull-through surgery, age, sex or gender, complications and outcomes. Articles that met the inclusion criteria with good to fair quality according to the Newcastle-Ottawa quality assessment and low bias score in the Cochran collaboration tool were reviewed.Results: Sixteen studies were eligible to be reviewed. The overall results of this study showed that due to more common short-term complications at neonatal period and lower contrast enema diagnostic accuracy in determining the transition zone, it seems to be reasonable decision to postpone surgery until the child is several months old. There was also no difference in terms of complications and outcomes of trans-anal pull-through surgery between females and males.Conclusion: It is not recommended to delay surgery too much for ages over 1 year. Ages between 3 and 12 months can be a good time for interventional treatment for HD.","PeriodicalId":55469,"journal":{"name":"Archives of Iranian Medicine","volume":"27 7","pages":"392-399"},"PeriodicalIF":1.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0